PMC:3727988 / 12339-13358 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3727988","sourcedb":"PMC","sourceid":"3727988","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3727988","text":"Whereas the presence of inflammatory processes during migraine attacks, serum levels of different proinflammatory molecules have been investigated. Several studies have found elevated levels of C-Reactive Protein (CRP), a marker of chronic low-grade inflammation, in patients with migraine [33,34]. Also the procalcitonin levels were investigated as indicators of inflammation in migraine patients with and without aura. Turan et al. found significantly high levels of PCT in patients with migraine during the attack compared to the interictal period (0.0485 vs 0.0298 ng/ml) [35]. An interesting fact was found by Guldiken et al. about the increase of soluble CD40 ligand (sCD40L). In this study, sCD40L amount was higher in the subgroup of migraineurs with aura than in those without aura and in rare attacks rather than in the frequent ones. In both comparisons the difference in the levels of sCD40L was not significant but these data may be related to the association of migraine with cardiovascular diseases [36].","tracks":[{"project":"2_test","denotations":[{"id":"23815568-17668468-60545014","span":{"begin":291,"end":293},"obj":"17668468"},{"id":"23815568-16492227-60545015","span":{"begin":294,"end":296},"obj":"16492227"},{"id":"23815568-21156441-60545016","span":{"begin":577,"end":579},"obj":"21156441"},{"id":"23815568-21331754-60545017","span":{"begin":1015,"end":1017},"obj":"21331754"}],"attributes":[{"subj":"23815568-17668468-60545014","pred":"source","obj":"2_test"},{"subj":"23815568-16492227-60545015","pred":"source","obj":"2_test"},{"subj":"23815568-21156441-60545016","pred":"source","obj":"2_test"},{"subj":"23815568-21331754-60545017","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#9399ec","default":true}]}]}}