PMC:3727638 / 66084-67203 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3727638","sourcedb":"PMC","sourceid":"3727638","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3727638","text":"However, in the current prospective study a number of results suggest that these patients are living longer than reported in many previous series. First, during the long follow-up (mean, 15.5 yr from MEN1 diagnosis; 24.5 yr from MEN1 onset), 23% of the 106 NIH MEN1/ZES patients died, which is comparable to the 28% ± 3% reported in 12 of the general MEN1 series in the literature that reported mortality percentages (1386 patients, see Table 12). However, the deaths in the NIH MEN1/ZES patients occurred over more than twice as long a follow-up period as the follow-up period reported in the literature cases (15.5 [NIH] vs 7.7 ± 1.0 yr from diagnosis of MEN1, n = 6 series]. Similarly for the 227 MEN1/PET deceased patients from the pooled literature, whose data came from 108 separate reports, they represented 18.8% ± 1.9% (data: 36 reports) of the total MEN1 patients being followed in these reports. However, similar to the 12 general MEN1 literature series, the percentage of patients that died in the pooled literature series occurred over less than half of the follow-up time (6.9 ± 1.3 yr) of the NIH series.","tracks":[]}