PMC:3724972 / 22201-22463 JSONTXT

{"project":"2_test","denotations":[{"id":"23673515-20972839-63233658","span":{"begin":147,"end":149},"obj":"20972839"},{"id":"23673515-22584716-63233659","span":{"begin":151,"end":153},"obj":"22584716"},{"id":"23673515-20496311-63233660","span":{"begin":193,"end":195},"obj":"20496311"}],"text":"Temozolomide, an oral alkylating agent typically used in chemotherapeutic treatment of astrocytoma and melanoma, has shown promise as monotherapy [62, 63], and in combination with pasireotide [64], as a treatment for aggressive pituitary adenomas and carcinomas."}