PMC:3713832 / 3163-3988 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3713832","sourcedb":"PMC","sourceid":"3713832","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3713832","text":"We conducted complete genome comparison and phylogenetic analysis on the basis of polymerase and spike protein. Pairwise genome sequence alignment was conducted by using EMBOSS Needle software (www.ebi.ac.uk/Tools/psa/emboss_needle/) with default parameters. The overall nucleotide sequences between Bat Rp-coronavirus/Shaanxi2011 and Bat Cp-coronavirus/Yunnan2011 indicated 88.7% nt identity. They shared 87.4%–89.5% nt identity with SARS-CoV, 88%–89.9% nt identity with the bat SARS-like CoV (bat SARS-CoV Rm1), and 87.6%–89.6% nt identity with the civet SARS-like CoV (civet SARS-CoV SZ16). On the other hand, comparison between the betacoronavirus genomes and human betacoronavirus (HCoV-OC43) showed only 49.9%–50.4% nt overall identity, whereas the betacoronavirus genomes and HCoV-EMC showed 52.1% nt overall identity.","tracks":[]}