PMC:3711907 / 11542-12581 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3711907","sourcedb":"PMC","sourceid":"3711907","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3711907","text":"Statistical analysis\nThe reported time to onset for different drugs with angioedema and hepatitis was visualized in box plots, using the “bwplot” function in the lattice package of R [18]. In these plots, the box demarks the interquartile range, the medians are marked with a dot, and whiskers extend to the most extreme data point that falls within 1.5 times the interquartile range of either end of the box; outliers beyond the whiskers are not displayed. Comparisons between long- and short-term treatments in the reported time-to-onset for each ADR were made with non-parametric Mann-Whitney tests. The null hypothesis is that there is no difference in reported time-to-onset between the two groups of drugs, for each respective ADR. The “wilcox. test” R function for a two-tailed and unpaired Wilcoxon rank sum test [19] was used, which is equivalent to the Mann-Whitney test [20]. Formal survival analysis was not possible, lacking information on the number of patients at risk at a given point in time after initiation of treatment.","divisions":[{"label":"Title","span":{"begin":0,"end":20}}],"tracks":[{"project":"NEUROSES","denotations":[{"id":"T246","span":{"begin":34,"end":38},"obj":"PATO_0001309"},{"id":"T247","span":{"begin":526,"end":530},"obj":"PATO_0001309"},{"id":"T248","span":{"begin":666,"end":670},"obj":"PATO_0001309"},{"id":"T249","span":{"begin":1004,"end":1008},"obj":"PATO_0001309"},{"id":"T250","span":{"begin":34,"end":38},"obj":"PATO_0000165"},{"id":"T251","span":{"begin":526,"end":530},"obj":"PATO_0000165"},{"id":"T252","span":{"begin":666,"end":670},"obj":"PATO_0000165"},{"id":"T253","span":{"begin":1004,"end":1008},"obj":"PATO_0000165"},{"id":"T254","span":{"begin":706,"end":711},"obj":"CHEBI_23888"},{"id":"T255","span":{"begin":146,"end":154},"obj":"PATO_0000173"},{"id":"T256","span":{"begin":759,"end":767},"obj":"PATO_0000173"},{"id":"T257","span":{"begin":262,"end":268},"obj":"PATO_0000465"},{"id":"T258","span":{"begin":313,"end":320},"obj":"PATO_0000390"},{"id":"T259","span":{"begin":478,"end":482},"obj":"PATO_0000573"},{"id":"T260","span":{"begin":488,"end":493},"obj":"PATO_0000574"},{"id":"T261","span":{"begin":488,"end":493},"obj":"PATO_0000569"},{"id":"T262","span":{"begin":778,"end":784},"obj":"PATO_0001880"},{"id":"T263","span":{"begin":887,"end":893},"obj":"CHEBI_48341"}],"attributes":[{"subj":"T246","pred":"source","obj":"NEUROSES"},{"subj":"T247","pred":"source","obj":"NEUROSES"},{"subj":"T248","pred":"source","obj":"NEUROSES"},{"subj":"T249","pred":"source","obj":"NEUROSES"},{"subj":"T250","pred":"source","obj":"NEUROSES"},{"subj":"T251","pred":"source","obj":"NEUROSES"},{"subj":"T252","pred":"source","obj":"NEUROSES"},{"subj":"T253","pred":"source","obj":"NEUROSES"},{"subj":"T254","pred":"source","obj":"NEUROSES"},{"subj":"T255","pred":"source","obj":"NEUROSES"},{"subj":"T256","pred":"source","obj":"NEUROSES"},{"subj":"T257","pred":"source","obj":"NEUROSES"},{"subj":"T258","pred":"source","obj":"NEUROSES"},{"subj":"T259","pred":"source","obj":"NEUROSES"},{"subj":"T260","pred":"source","obj":"NEUROSES"},{"subj":"T261","pred":"source","obj":"NEUROSES"},{"subj":"T262","pred":"source","obj":"NEUROSES"},{"subj":"T263","pred":"source","obj":"NEUROSES"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"NEUROSES","color":"#e8ec93","default":true}]}]}}