PMC:3660126 / 44199-46297 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3660126","sourcedb":"PMC","sourceid":"3660126","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3660126","text":"Hormones in mood disorders\nDehydroepiandrosterone (DHEA) is an androgen produced by the adrenal glands, levels of which tend to decrease during mid-life in men and women. Lower levels of DHEA have been reported in patients with major depression, and use of DHEA has been associated with improved mood. An increase in DHEA sulfate, the primary metabolite of DHEA, has also been associated with improvement in depression and dysthymia.156–157 In a randomized controlled trial, 23 men and 23 women with major or minor mid-life depression were given DHEA 90 mg/day for three weeks, then 450 mg/day for a further three weeks, or placebo for six weeks. A 50% or greater reduction in baseline Hamilton Depression Rating scores was observed in the 23 subjects who took DHEA and in 13 subjects who took placebo. Patients taking DHEA also showed improvement in sexual function.158 DHEA has been used effectively in patients with human immunodeficiency virus/acquired immune deficiency syndrome and subsyndromal depression or chronic dysthymia. Of 145 such patients given DHEA 100–400 mg/day for 8 weeks, 64% showed a more than 50% reduction in depression scores compared with 38% of those given placebo.159 The response was maintained for 8 months of follow-up, and was higher among those with increased levels of DHEA sulfate.159 Arguably, subsyndromal depression and dysthymia are not the same as major depression. In a recent study, DHEA 100 mg/day or placebo was administered to 26 patients with anorexia nervosa, whose assessment included mood symptoms. Patients receiving DHEA experienced significant improvement in mood and body mass index, although there was no difference in bone marrow density. Thus, comorbid depression in patients with eating disorders may benefit from the use of DHEA.160 DHEA should be used in low doses in bipolar patients because it may induce manic-like symptoms, irritation, and bouts of aggression, and increase testosterone and estrogen levels, resulting in an elevated risk of uterine or breast cancer, vaginal bleeding, endometrial hyperplasia, and venous thrombosis.57","divisions":[{"label":"Title","span":{"begin":0,"end":26}}],"tracks":[{"project":"NEUROSES","denotations":[{"id":"T1831","span":{"begin":27,"end":49},"obj":"CHEBI_28689"},{"id":"T1832","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1833","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1834","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1835","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1836","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1837","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1838","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1839","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1840","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1841","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1842","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1843","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1844","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1845","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1846","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1847","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1848","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1849","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1850","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1851","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1852","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1853","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1854","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1855","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1856","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1857","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1858","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1859","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1860","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1861","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1862","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1863","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1864","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1865","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1866","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1867","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1868","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1869","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1870","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1871","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1872","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1873","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1874","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1875","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1876","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1877","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1878","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1879","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1880","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1881","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1882","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1883","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1884","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1885","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1886","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1887","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1888","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1889","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1890","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1891","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1892","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1893","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1894","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1895","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1896","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1897","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1898","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1899","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1900","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1901","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1902","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1903","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1904","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1905","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1906","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1907","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1908","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1909","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1910","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1911","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1912","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1913","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1914","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1915","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1916","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1917","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1918","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1919","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1920","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1921","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1922","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1923","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1924","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1925","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1926","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1927","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1928","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1929","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1930","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1931","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1932","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1933","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1934","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1935","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1936","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1937","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1938","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1939","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1940","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1941","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1942","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1943","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1944","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1945","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1946","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1947","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1948","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1949","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1950","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1951","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1952","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1953","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1954","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1955","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1956","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1957","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1958","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1959","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1960","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1961","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1962","span":{"begin":51,"end":55},"obj":"CHEBI_28689"},{"id":"T1963","span":{"begin":187,"end":191},"obj":"CHEBI_28689"},{"id":"T1964","span":{"begin":257,"end":261},"obj":"CHEBI_28689"},{"id":"T1965","span":{"begin":357,"end":361},"obj":"CHEBI_28689"},{"id":"T1966","span":{"begin":546,"end":550},"obj":"CHEBI_28689"},{"id":"T1967","span":{"begin":761,"end":765},"obj":"CHEBI_28689"},{"id":"T1968","span":{"begin":819,"end":823},"obj":"CHEBI_28689"},{"id":"T1969","span":{"begin":871,"end":875},"obj":"CHEBI_28689"},{"id":"T1970","span":{"begin":1061,"end":1065},"obj":"CHEBI_28689"},{"id":"T1971","span":{"begin":1426,"end":1430},"obj":"CHEBI_28689"},{"id":"T1972","span":{"begin":1568,"end":1572},"obj":"CHEBI_28689"},{"id":"T1973","span":{"begin":1783,"end":1787},"obj":"CHEBI_28689"},{"id":"T1974","span":{"begin":1792,"end":1796},"obj":"CHEBI_28689"},{"id":"T1975","span":{"begin":234,"end":244},"obj":"PM3425"},{"id":"T1976","span":{"begin":408,"end":418},"obj":"PM3425"},{"id":"T1977","span":{"begin":524,"end":534},"obj":"PM3425"},{"id":"T1978","span":{"begin":695,"end":705},"obj":"PM3425"},{"id":"T1979","span":{"begin":1001,"end":1011},"obj":"PM3425"},{"id":"T1980","span":{"begin":1134,"end":1144},"obj":"PM3425"},{"id":"T1981","span":{"begin":1344,"end":1354},"obj":"PM3425"},{"id":"T1982","span":{"begin":1395,"end":1405},"obj":"PM3425"},{"id":"T1983","span":{"begin":1710,"end":1720},"obj":"PM3425"},{"id":"T1984","span":{"begin":925,"end":941},"obj":"PM4584"},{"id":"T1985","span":{"begin":925,"end":941},"obj":"PM4584"},{"id":"T1986","span":{"begin":234,"end":244},"obj":"PM3425"},{"id":"T1987","span":{"begin":408,"end":418},"obj":"PM3425"},{"id":"T1988","span":{"begin":524,"end":534},"obj":"PM3425"},{"id":"T1989","span":{"begin":695,"end":705},"obj":"PM3425"},{"id":"T1990","span":{"begin":1001,"end":1011},"obj":"PM3425"},{"id":"T1991","span":{"begin":1134,"end":1144},"obj":"PM3425"},{"id":"T1992","span":{"begin":1344,"end":1354},"obj":"PM3425"},{"id":"T1993","span":{"begin":1395,"end":1405},"obj":"PM3425"},{"id":"T1994","span":{"begin":1710,"end":1720},"obj":"PM3425"}],"attributes":[{"subj":"T1831","pred":"source","obj":"NEUROSES"},{"subj":"T1832","pred":"source","obj":"NEUROSES"},{"subj":"T1833","pred":"source","obj":"NEUROSES"},{"subj":"T1834","pred":"source","obj":"NEUROSES"},{"subj":"T1835","pred":"source","obj":"NEUROSES"},{"subj":"T1836","pred":"source","obj":"NEUROSES"},{"subj":"T1837","pred":"source","obj":"NEUROSES"},{"subj":"T1838","pred":"source","obj":"NEUROSES"},{"subj":"T1839","pred":"source","obj":"NEUROSES"},{"subj":"T1840","pred":"source","obj":"NEUROSES"},{"subj":"T1841","pred":"source","obj":"NEUROSES"},{"subj":"T1842","pred":"source","obj":"NEUROSES"},{"subj":"T1843","pred":"source","obj":"NEUROSES"},{"subj":"T1844","pred":"source","obj":"NEUROSES"},{"subj":"T1845","pred":"source","obj":"NEUROSES"},{"subj":"T1846","pred":"source","obj":"NEUROSES"},{"subj":"T1847","pred":"source","obj":"NEUROSES"},{"subj":"T1848","pred":"source","obj":"NEUROSES"},{"subj":"T1849","pred":"source","obj":"NEUROSES"},{"subj":"T1850","pred":"source","obj":"NEUROSES"},{"subj":"T1851","pred":"source","obj":"NEUROSES"},{"subj":"T1852","pred":"source","obj":"NEUROSES"},{"subj":"T1853","pred":"source","obj":"NEUROSES"},{"subj":"T1854","pred":"source","obj":"NEUROSES"},{"subj":"T1855","pred":"source","obj":"NEUROSES"},{"subj":"T1856","pred":"source","obj":"NEUROSES"},{"subj":"T1857","pred":"source","obj":"NEUROSES"},{"subj":"T1858","pred":"source","obj":"NEUROSES"},{"subj":"T1859","pred":"source","obj":"NEUROSES"},{"subj":"T1860","pred":"source","obj":"NEUROSES"},{"subj":"T1861","pred":"source","obj":"NEUROSES"},{"subj":"T1862","pred":"source","obj":"NEUROSES"},{"subj":"T1863","pred":"source","obj":"NEUROSES"},{"subj":"T1864","pred":"source","obj":"NEUROSES"},{"subj":"T1865","pred":"source","obj":"NEUROSES"},{"subj":"T1866","pred":"source","obj":"NEUROSES"},{"subj":"T1867","pred":"source","obj":"NEUROSES"},{"subj":"T1868","pred":"source","obj":"NEUROSES"},{"subj":"T1869","pred":"source","obj":"NEUROSES"},{"subj":"T1870","pred":"source","obj":"NEUROSES"},{"subj":"T1871","pred":"source","obj":"NEUROSES"},{"subj":"T1872","pred":"source","obj":"NEUROSES"},{"subj":"T1873","pred":"source","obj":"NEUROSES"},{"subj":"T1874","pred":"source","obj":"NEUROSES"},{"subj":"T1875","pred":"source","obj":"NEUROSES"},{"subj":"T1876","pred":"source","obj":"NEUROSES"},{"subj":"T1877","pred":"source","obj":"NEUROSES"},{"subj":"T1878","pred":"source","obj":"NEUROSES"},{"subj":"T1879","pred":"source","obj":"NEUROSES"},{"subj":"T1880","pred":"source","obj":"NEUROSES"},{"subj":"T1881","pred":"source","obj":"NEUROSES"},{"subj":"T1882","pred":"source","obj":"NEUROSES"},{"subj":"T1883","pred":"source","obj":"NEUROSES"},{"subj":"T1884","pred":"source","obj":"NEUROSES"},{"subj":"T1885","pred":"source","obj":"NEUROSES"},{"subj":"T1886","pred":"source","obj":"NEUROSES"},{"subj":"T1887","pred":"source","obj":"NEUROSES"},{"subj":"T1888","pred":"source","obj":"NEUROSES"},{"subj":"T1889","pred":"source","obj":"NEUROSES"},{"subj":"T1890","pred":"source","obj":"NEUROSES"},{"subj":"T1891","pred":"source","obj":"NEUROSES"},{"subj":"T1892","pred":"source","obj":"NEUROSES"},{"subj":"T1893","pred":"source","obj":"NEUROSES"},{"subj":"T1894","pred":"source","obj":"NEUROSES"},{"subj":"T1895","pred":"source","obj":"NEUROSES"},{"subj":"T1896","pred":"source","obj":"NEUROSES"},{"subj":"T1897","pred":"source","obj":"NEUROSES"},{"subj":"T1898","pred":"source","obj":"NEUROSES"},{"subj":"T1899","pred":"source","obj":"NEUROSES"},{"subj":"T1900","pred":"source","obj":"NEUROSES"},{"subj":"T1901","pred":"source","obj":"NEUROSES"},{"subj":"T1902","pred":"source","obj":"NEUROSES"},{"subj":"T1903","pred":"source","obj":"NEUROSES"},{"subj":"T1904","pred":"source","obj":"NEUROSES"},{"subj":"T1905","pred":"source","obj":"NEUROSES"},{"subj":"T1906","pred":"source","obj":"NEUROSES"},{"subj":"T1907","pred":"source","obj":"NEUROSES"},{"subj":"T1908","pred":"source","obj":"NEUROSES"},{"subj":"T1909","pred":"source","obj":"NEUROSES"},{"subj":"T1910","pred":"source","obj":"NEUROSES"},{"subj":"T1911","pred":"source","obj":"NEUROSES"},{"subj":"T1912","pred":"source","obj":"NEUROSES"},{"subj":"T1913","pred":"source","obj":"NEUROSES"},{"subj":"T1914","pred":"source","obj":"NEUROSES"},{"subj":"T1915","pred":"source","obj":"NEUROSES"},{"subj":"T1916","pred":"source","obj":"NEUROSES"},{"subj":"T1917","pred":"source","obj":"NEUROSES"},{"subj":"T1918","pred":"source","obj":"NEUROSES"},{"subj":"T1919","pred":"source","obj":"NEUROSES"},{"subj":"T1920","pred":"source","obj":"NEUROSES"},{"subj":"T1921","pred":"source","obj":"NEUROSES"},{"subj":"T1922","pred":"source","obj":"NEUROSES"},{"subj":"T1923","pred":"source","obj":"NEUROSES"},{"subj":"T1924","pred":"source","obj":"NEUROSES"},{"subj":"T1925","pred":"source","obj":"NEUROSES"},{"subj":"T1926","pred":"source","obj":"NEUROSES"},{"subj":"T1927","pred":"source","obj":"NEUROSES"},{"subj":"T1928","pred":"source","obj":"NEUROSES"},{"subj":"T1929","pred":"source","obj":"NEUROSES"},{"subj":"T1930","pred":"source","obj":"NEUROSES"},{"subj":"T1931","pred":"source","obj":"NEUROSES"},{"subj":"T1932","pred":"source","obj":"NEUROSES"},{"subj":"T1933","pred":"source","obj":"NEUROSES"},{"subj":"T1934","pred":"source","obj":"NEUROSES"},{"subj":"T1935","pred":"source","obj":"NEUROSES"},{"subj":"T1936","pred":"source","obj":"NEUROSES"},{"subj":"T1937","pred":"source","obj":"NEUROSES"},{"subj":"T1938","pred":"source","obj":"NEUROSES"},{"subj":"T1939","pred":"source","obj":"NEUROSES"},{"subj":"T1940","pred":"source","obj":"NEUROSES"},{"subj":"T1941","pred":"source","obj":"NEUROSES"},{"subj":"T1942","pred":"source","obj":"NEUROSES"},{"subj":"T1943","pred":"source","obj":"NEUROSES"},{"subj":"T1944","pred":"source","obj":"NEUROSES"},{"subj":"T1945","pred":"source","obj":"NEUROSES"},{"subj":"T1946","pred":"source","obj":"NEUROSES"},{"subj":"T1947","pred":"source","obj":"NEUROSES"},{"subj":"T1948","pred":"source","obj":"NEUROSES"},{"subj":"T1949","pred":"source","obj":"NEUROSES"},{"subj":"T1950","pred":"source","obj":"NEUROSES"},{"subj":"T1951","pred":"source","obj":"NEUROSES"},{"subj":"T1952","pred":"source","obj":"NEUROSES"},{"subj":"T1953","pred":"source","obj":"NEUROSES"},{"subj":"T1954","pred":"source","obj":"NEUROSES"},{"subj":"T1955","pred":"source","obj":"NEUROSES"},{"subj":"T1956","pred":"source","obj":"NEUROSES"},{"subj":"T1957","pred":"source","obj":"NEUROSES"},{"subj":"T1958","pred":"source","obj":"NEUROSES"},{"subj":"T1959","pred":"source","obj":"NEUROSES"},{"subj":"T1960","pred":"source","obj":"NEUROSES"},{"subj":"T1961","pred":"source","obj":"NEUROSES"},{"subj":"T1962","pred":"source","obj":"NEUROSES"},{"subj":"T1963","pred":"source","obj":"NEUROSES"},{"subj":"T1964","pred":"source","obj":"NEUROSES"},{"subj":"T1965","pred":"source","obj":"NEUROSES"},{"subj":"T1966","pred":"source","obj":"NEUROSES"},{"subj":"T1967","pred":"source","obj":"NEUROSES"},{"subj":"T1968","pred":"source","obj":"NEUROSES"},{"subj":"T1969","pred":"source","obj":"NEUROSES"},{"subj":"T1970","pred":"source","obj":"NEUROSES"},{"subj":"T1971","pred":"source","obj":"NEUROSES"},{"subj":"T1972","pred":"source","obj":"NEUROSES"},{"subj":"T1973","pred":"source","obj":"NEUROSES"},{"subj":"T1974","pred":"source","obj":"NEUROSES"},{"subj":"T1975","pred":"source","obj":"NEUROSES"},{"subj":"T1976","pred":"source","obj":"NEUROSES"},{"subj":"T1977","pred":"source","obj":"NEUROSES"},{"subj":"T1978","pred":"source","obj":"NEUROSES"},{"subj":"T1979","pred":"source","obj":"NEUROSES"},{"subj":"T1980","pred":"source","obj":"NEUROSES"},{"subj":"T1981","pred":"source","obj":"NEUROSES"},{"subj":"T1982","pred":"source","obj":"NEUROSES"},{"subj":"T1983","pred":"source","obj":"NEUROSES"},{"subj":"T1984","pred":"source","obj":"NEUROSES"},{"subj":"T1985","pred":"source","obj":"NEUROSES"},{"subj":"T1986","pred":"source","obj":"NEUROSES"},{"subj":"T1987","pred":"source","obj":"NEUROSES"},{"subj":"T1988","pred":"source","obj":"NEUROSES"},{"subj":"T1989","pred":"source","obj":"NEUROSES"},{"subj":"T1990","pred":"source","obj":"NEUROSES"},{"subj":"T1991","pred":"source","obj":"NEUROSES"},{"subj":"T1992","pred":"source","obj":"NEUROSES"},{"subj":"T1993","pred":"source","obj":"NEUROSES"},{"subj":"T1994","pred":"source","obj":"NEUROSES"}]},{"project":"2_test","denotations":[{"id":"23700366-10376113-76000714","span":{"begin":433,"end":436},"obj":"10376113"},{"id":"23700366-10200751-76000714","span":{"begin":433,"end":436},"obj":"10200751"},{"id":"23700366-15699292-76000715","span":{"begin":867,"end":870},"obj":"15699292"},{"id":"23700366-16390890-76000716","span":{"begin":1193,"end":1196},"obj":"16390890"},{"id":"23700366-16390890-76000717","span":{"begin":1317,"end":1320},"obj":"16390890"},{"id":"23700366-22858403-76000718","span":{"begin":1788,"end":1791},"obj":"22858403"}],"attributes":[{"subj":"23700366-10376113-76000714","pred":"source","obj":"2_test"},{"subj":"23700366-10200751-76000714","pred":"source","obj":"2_test"},{"subj":"23700366-15699292-76000715","pred":"source","obj":"2_test"},{"subj":"23700366-16390890-76000716","pred":"source","obj":"2_test"},{"subj":"23700366-16390890-76000717","pred":"source","obj":"2_test"},{"subj":"23700366-22858403-76000718","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"NEUROSES","color":"#ecd393","default":true},{"id":"2_test","color":"#b993ec"}]}]}}