PMC:3660126 / 3385-4973 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3660126","sourcedb":"PMC","sourceid":"3660126","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3660126","text":"Literature search\nA search of the PubMed, Medline, Google Scholar, and Quertile databases was done using the key phrases “complementary and alternative medicine” and “integrative medicine combined with mood disorders and major depression”, and relevant articles published over the past two decades (1992–2012) in the peer-reviewed English language journals were retrieved. Other keywords, including “botanicals”, “phytomedicine”, “nutrients”, “herbs”, “dietary supplements”, “vitamins”, “fatty acids”, “folate”, “hormones”, “exercise”, “meditation”, “yoga”, “Ayurveda”, “homeopathy”, and “mind-body-spirit” were combined with “major depression” and “mood disorders” for more specific searches. More than 30,000 articles were retrieved using this method. Many articles were excluded, including articles without abstracts (n = 529), papers not published in the English language (n = 840), full articles not being available (n = 215), and duplication of articles across searches (n = 12,120), along with many papers unrelated to the topic under consideration (n = 16,046). Only 250 papers were retained for further review. Thirty-seven articles that described single cases and small case series (less than five subjects) were also excluded. In total, the authors selected 213 articles, which included open-label clinical trials, randomized controlled trials, systematic reviews, and meta-analyses addressing use of CAM in the management of major depression and other mood disorders. Eight references were added during revisions of this manuscript and one citation was deleted (see Figure 1).","divisions":[{"label":"Title","span":{"begin":0,"end":17}}],"tracks":[{"project":"NEUROSES","denotations":[{"id":"T96","span":{"begin":179,"end":187},"obj":"CHEBI_23888"},{"id":"T97","span":{"begin":1174,"end":1179},"obj":"PATO_0000587"},{"id":"T98","span":{"begin":1298,"end":1302},"obj":"PATO_0000610"},{"id":"T99","span":{"begin":1303,"end":1308},"obj":"CHEBI_35209"},{"id":"T100","span":{"begin":1443,"end":1453},"obj":"PM3425"},{"id":"T101","span":{"begin":1443,"end":1453},"obj":"PM3425"}],"attributes":[{"subj":"T96","pred":"source","obj":"NEUROSES"},{"subj":"T97","pred":"source","obj":"NEUROSES"},{"subj":"T98","pred":"source","obj":"NEUROSES"},{"subj":"T99","pred":"source","obj":"NEUROSES"},{"subj":"T100","pred":"source","obj":"NEUROSES"},{"subj":"T101","pred":"source","obj":"NEUROSES"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"NEUROSES","color":"#a1ec93","default":true}]}]}}