PMC:3656366 / 15623-16311 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3656366","sourcedb":"PMC","sourceid":"3656366","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3656366","text":"NAcb-DBS Reduced Anxiety-Related Behavior in HAB, but not NAB Mice\nGiven that HAB mice are characterized by enhanced anxiety-related behavior (Kromer et al, 2005), we also studied possible effects of NAcb-DBS on emotionality in HABs. In comparison with NAcb-sham HAB controls, four repetitions of NAcb-DBS greatly reduced the latency to eat a preferred food offered in the center of the testing area of the novelty suppressed feeding paradigm (t=3.064, P=0.007; Figure 3c), indicating a clear anxiolytic effect in HAB mice. In contrast, there was no significant anxiolytic effect of repeated NAcb-DBS as compared with NAcb-sham in NAB animals (t=1.684, P=0.111; Supplementary Figure S2B).","divisions":[{"label":"Title","span":{"begin":0,"end":66}}],"tracks":[{"project":"2_test","denotations":[{"id":"23325324-15858064-76171898","span":{"begin":157,"end":161},"obj":"15858064"}],"attributes":[{"subj":"23325324-15858064-76171898","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ec93e2","default":true}]}]}}