PMC:3589482 / 36632-36874 JSONTXT

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T16214","span":{"begin":74,"end":83},"obj":"VBN"},{"id":"T16213","span":{"begin":60,"end":73},"obj":"RB"},{"id":"T16212","span":{"begin":56,"end":59},"obj":"VBD"},{"id":"T16211","span":{"begin":47,"end":55},"obj":"NN"},{"id":"T16210","span":{"begin":38,"end":46},"obj":"NN"},{"id":"T16209","span":{"begin":29,"end":37},"obj":"JJ"},{"id":"T16208","span":{"begin":14,"end":28},"obj":"JJ"},{"id":"T16207","span":{"begin":9,"end":13},"obj":"IN"},{"id":"T16206","span":{"begin":3,"end":8},"obj":"VBD"},{"id":"T16205","span":{"begin":0,"end":2},"obj":"PRP"},{"id":"T16248","span":{"begin":241,"end":242},"obj":"."},{"id":"T16247","span":{"begin":233,"end":241},"obj":"NN"},{"id":"T16246","span":{"begin":224,"end":232},"obj":"NN"},{"id":"T16245","span":{"begin":215,"end":223},"obj":"JJ"},{"id":"T16244","span":{"begin":206,"end":214},"obj":"JJ"},{"id":"T16243","span":{"begin":194,"end":205},"obj":"JJ"},{"id":"T16242","span":{"begin":190,"end":193},"obj":"IN"},{"id":"T16241","span":{"begin":181,"end":189},"obj":"VBN"},{"id":"T16240","span":{"begin":178,"end":180},"obj":"VBZ"},{"id":"T16239","span":{"begin":176,"end":177},"obj":"NN"},{"id":"T16238","span":{"begin":175,"end":176},"obj":":"},{"id":"T16237","span":{"begin":170,"end":175},"obj":"NNP"},{"id":"T16236","span":{"begin":159,"end":169},"obj":"JJ"},{"id":"T16235","span":{"begin":154,"end":158},"obj":"IN"},{"id":"T16234","span":{"begin":143,"end":153},"obj":"VBG"},{"id":"T16233","span":{"begin":141,"end":142},"obj":","},{"id":"T16232","span":{"begin":140,"end":141},"obj":"-RRB-"},{"id":"T16231","span":{"begin":138,"end":140},"obj":"NNP"},{"id":"T16230","span":{"begin":133,"end":137},"obj":"NNP"},{"id":"T16229","span":{"begin":132,"end":133},"obj":"-LRB-"},{"id":"T16228","span":{"begin":127,"end":131},"obj":"NNS"},{"id":"T16227","span":{"begin":125,"end":126},"obj":"CD"},{"id":"T16226","span":{"begin":124,"end":125},"obj":"VBD"},{"id":"T16225","span":{"begin":123,"end":124},"obj":"NNP"},{"id":"T16224","span":{"begin":118,"end":123},"obj":"NNP"},{"id":"T16223","span":{"begin":115,"end":117},"obj":"IN"},{"id":"T16222","span":{"begin":105,"end":114},"obj":"VBD"},{"id":"T16221","span":{"begin":101,"end":104},"obj":"CC"},{"id":"T16220","span":{"begin":96,"end":100},"obj":"NNS"},{"id":"T16219","span":{"begin":94,"end":95},"obj":"CD"},{"id":"T16218","span":{"begin":93,"end":94},"obj":"VBD"},{"id":"T16217","span":{"begin":92,"end":93},"obj":"NNP"},{"id":"T16216","span":{"begin":87,"end":92},"obj":"NNP"},{"id":"T16215","span":{"begin":84,"end":86},"obj":"IN"}],"relations":[{"id":"R11906","pred":"nsubj","subj":"T16205","obj":"T16206"},{"id":"R11907","pred":"ROOT","subj":"T16206","obj":"T16206"},{"id":"R11908","pred":"mark","subj":"T16207","obj":"T16214"},{"id":"R11909","pred":"amod","subj":"T16208","obj":"T16211"},{"id":"R11910","pred":"amod","subj":"T16209","obj":"T16211"},{"id":"R11911","pred":"compound","subj":"T16210","obj":"T16211"},{"id":"R11912","pred":"nsubjpass","subj":"T16211","obj":"T16214"},{"id":"R11913","pred":"auxpass","subj":"T16212","obj":"T16214"},{"id":"R11914","pred":"advmod","subj":"T16213","obj":"T16214"},{"id":"R11915","pred":"ccomp","subj":"T16214","obj":"T16206"},{"id":"R11916","pred":"prep","subj":"T16215","obj":"T16214"},{"id":"R11917","pred":"compound","subj":"T16216","obj":"T16217"},{"id":"R11918","pred":"pobj","subj":"T16217","obj":"T16215"},{"id":"R11919","pred":"advcl","subj":"T16218","obj":"T16214"},{"id":"R11920","pred":"nummod","subj":"T16219","obj":"T16220"},{"id":"R11921","pred":"dobj","subj":"T16220","obj":"T16218"},{"id":"R11922","pred":"cc","subj":"T16221","obj":"T16218"},{"id":"R11923","pred":"conj","subj":"T16222","obj":"T16218"},{"id":"R11924","pred":"prep","subj":"T16223","obj":"T16222"},{"id":"R11925","pred":"compound","subj":"T16224","obj":"T16225"},{"id":"R11926","pred":"pobj","subj":"T16225","obj":"T16223"},{"id":"R11927","pred":"conj","subj":"T16226","obj":"T16218"},{"id":"R11928","pred":"nummod","subj":"T16227","obj":"T16228"},{"id":"R11929","pred":"dobj","subj":"T16228","obj":"T16226"},{"id":"R11930","pred":"punct","subj":"T16229","obj":"T16228"},{"id":"R11931","pred":"compound","subj":"T16230","obj":"T16231"},{"id":"R11932","pred":"appos","subj":"T16231","obj":"T16228"},{"id":"R11933","pred":"punct","subj":"T16232","obj":"T16228"},{"id":"R11934","pred":"punct","subj":"T16233","obj":"T16226"},{"id":"R11935","pred":"advcl","subj":"T16234","obj":"T16226"},{"id":"R11936","pred":"mark","subj":"T16235","obj":"T16241"},{"id":"R11937","pred":"amod","subj":"T16236","obj":"T16239"},{"id":"R11938","pred":"compound","subj":"T16237","obj":"T16239"},{"id":"R11939","pred":"punct","subj":"T16238","obj":"T16239"},{"id":"R11940","pred":"nsubjpass","subj":"T16239","obj":"T16241"},{"id":"R11941","pred":"auxpass","subj":"T16240","obj":"T16241"},{"id":"R11942","pred":"ccomp","subj":"T16241","obj":"T16234"},{"id":"R11943","pred":"prep","subj":"T16242","obj":"T16241"},{"id":"R11944","pred":"amod","subj":"T16243","obj":"T16247"},{"id":"R11945","pred":"amod","subj":"T16244","obj":"T16247"},{"id":"R11946","pred":"amod","subj":"T16245","obj":"T16247"},{"id":"R11947","pred":"compound","subj":"T16246","obj":"T16247"},{"id":"R11948","pred":"pobj","subj":"T16247","obj":"T16242"},{"id":"R11949","pred":"punct","subj":"T16248","obj":"T16206"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"pmc-enju-pas","denotations":[{"id":"T15906","span":{"begin":233,"end":241},"obj":"NN"},{"id":"T15905","span":{"begin":224,"end":232},"obj":"NN"},{"id":"T15904","span":{"begin":215,"end":223},"obj":"JJ"},{"id":"T15903","span":{"begin":206,"end":214},"obj":"NN"},{"id":"T15902","span":{"begin":194,"end":205},"obj":"JJ"},{"id":"T15901","span":{"begin":190,"end":193},"obj":"IN"},{"id":"T15900","span":{"begin":181,"end":189},"obj":"VB"},{"id":"T15899","span":{"begin":178,"end":180},"obj":"VB"},{"id":"T15898","span":{"begin":170,"end":177},"obj":"NN"},{"id":"T15897","span":{"begin":159,"end":169},"obj":"JJ"},{"id":"T15896","span":{"begin":154,"end":158},"obj":"IN"},{"id":"T15895","span":{"begin":143,"end":153},"obj":"VB"},{"id":"T15894","span":{"begin":141,"end":142},"obj":"-COMMA-"},{"id":"T15893","span":{"begin":140,"end":141},"obj":"-RRB-"},{"id":"T15892","span":{"begin":138,"end":140},"obj":"NN"},{"id":"T15891","span":{"begin":133,"end":137},"obj":"NNP"},{"id":"T15890","span":{"begin":132,"end":133},"obj":"-LRB-"},{"id":"T15889","span":{"begin":127,"end":131},"obj":"NN"},{"id":"T15888","span":{"begin":118,"end":126},"obj":"NN"},{"id":"T15887","span":{"begin":115,"end":117},"obj":"IN"},{"id":"T15886","span":{"begin":105,"end":114},"obj":"VB"},{"id":"T15885","span":{"begin":101,"end":104},"obj":"CC"},{"id":"T15884","span":{"begin":96,"end":100},"obj":"NN"},{"id":"T15883","span":{"begin":87,"end":95},"obj":"JJ"},{"id":"T15882","span":{"begin":84,"end":86},"obj":"IN"},{"id":"T15881","span":{"begin":74,"end":83},"obj":"VB"},{"id":"T15880","span":{"begin":60,"end":73},"obj":"RB"},{"id":"T15879","span":{"begin":56,"end":59},"obj":"VB"},{"id":"T15878","span":{"begin":47,"end":55},"obj":"NN"},{"id":"T15877","span":{"begin":38,"end":46},"obj":"NN"},{"id":"T15876","span":{"begin":29,"end":37},"obj":"NN"},{"id":"T15875","span":{"begin":14,"end":28},"obj":"JJ"},{"id":"T15874","span":{"begin":9,"end":13},"obj":"IN"},{"id":"T15873","span":{"begin":3,"end":8},"obj":"VB"},{"id":"T15872","span":{"begin":0,"end":2},"obj":"PRP"}],"relations":[{"id":"R11704","pred":"arg1Of","subj":"T15872","obj":"T15873"},{"id":"R11705","pred":"arg1Of","subj":"T15873","obj":"T15894"},{"id":"R11706","pred":"modOf","subj":"T15873","obj":"T15895"},{"id":"R11707","pred":"arg1Of","subj":"T15878","obj":"T15875"},{"id":"R11708","pred":"arg1Of","subj":"T15878","obj":"T15876"},{"id":"R11709","pred":"arg1Of","subj":"T15878","obj":"T15877"},{"id":"R11710","pred":"arg1Of","subj":"T15878","obj":"T15879"},{"id":"R11711","pred":"arg2Of","subj":"T15878","obj":"T15881"},{"id":"R11712","pred":"arg1Of","subj":"T15878","obj":"T15886"},{"id":"R11713","pred":"arg2Of","subj":"T15881","obj":"T15879"},{"id":"R11714","pred":"arg1Of","subj":"T15881","obj":"T15880"},{"id":"R11715","pred":"arg1Of","subj":"T15881","obj":"T15882"},{"id":"R11716","pred":"arg1Of","subj":"T15881","obj":"T15885"},{"id":"R11717","pred":"arg2Of","subj":"T15884","obj":"T15882"},{"id":"R11718","pred":"arg1Of","subj":"T15884","obj":"T15883"},{"id":"R11719","pred":"arg2Of","subj":"T15885","obj":"T15873"},{"id":"R11720","pred":"arg1Of","subj":"T15885","obj":"T15874"},{"id":"R11721","pred":"arg2Of","subj":"T15886","obj":"T15885"},{"id":"R11722","pred":"arg1Of","subj":"T15886","obj":"T15887"},{"id":"R11723","pred":"arg2Of","subj":"T15889","obj":"T15887"},{"id":"R11724","pred":"arg1Of","subj":"T15889","obj":"T15888"},{"id":"R11725","pred":"arg2Of","subj":"T15892","obj":"T15886"},{"id":"R11726","pred":"arg2Of","subj":"T15892","obj":"T15890"},{"id":"R11727","pred":"arg1Of","subj":"T15892","obj":"T15891"},{"id":"R11728","pred":"arg3Of","subj":"T15893","obj":"T15890"},{"id":"R11729","pred":"arg1Of","subj":"T15898","obj":"T15897"},{"id":"R11730","pred":"arg1Of","subj":"T15898","obj":"T15899"},{"id":"R11731","pred":"arg2Of","subj":"T15898","obj":"T15900"},{"id":"R11732","pred":"arg2Of","subj":"T15900","obj":"T15895"},{"id":"R11733","pred":"arg1Of","subj":"T15900","obj":"T15896"},{"id":"R11734","pred":"arg2Of","subj":"T15900","obj":"T15899"},{"id":"R11735","pred":"arg1Of","subj":"T15900","obj":"T15901"},{"id":"R11736","pred":"arg2Of","subj":"T15906","obj":"T15901"},{"id":"R11737","pred":"arg1Of","subj":"T15906","obj":"T15902"},{"id":"R11738","pred":"arg1Of","subj":"T15906","obj":"T15903"},{"id":"R11739","pred":"arg1Of","subj":"T15906","obj":"T15904"},{"id":"R11740","pred":"arg1Of","subj":"T15906","obj":"T15905"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T15768","span":{"begin":206,"end":214},"obj":"Protein"},{"id":"T15767","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T15766","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T15765","span":{"begin":87,"end":92},"obj":"Protein"},{"id":"T15764","span":{"begin":29,"end":37},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T15961","span":{"begin":206,"end":214},"obj":"http://www.uniprot.org/uniprot/P05120"},{"id":"T15960","span":{"begin":29,"end":37},"obj":"http://www.uniprot.org/uniprot/P05120"},{"id":"T15954","span":{"begin":118,"end":123},"obj":"http://www.uniprot.org/uniprot/P28033"},{"id":"T15953","span":{"begin":87,"end":92},"obj":"http://www.uniprot.org/uniprot/P28033"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"sentences","denotations":[{"id":"T15713","span":{"begin":0,"end":242},"obj":"Sentence"},{"id":"T222","span":{"begin":0,"end":242},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"simple1","denotations":[{"id":"T15788","span":{"begin":206,"end":214},"obj":"Protein"},{"id":"T15787","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T15786","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T15785","span":{"begin":87,"end":92},"obj":"Protein"},{"id":"T15784","span":{"begin":29,"end":37},"obj":"Protein"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T15934","span":{"begin":29,"end":37},"obj":"Protein"},{"id":"T15946","span":{"begin":14,"end":28},"obj":"Positive_regulation"},{"id":"T15945","span":{"begin":105,"end":114},"obj":"Negative_regulation"},{"id":"T15944","span":{"begin":194,"end":205},"obj":"Positive_regulation"},{"id":"T15943","span":{"begin":181,"end":189},"obj":"Positive_regulation"},{"id":"T15942","span":{"begin":74,"end":83},"obj":"Positive_regulation"},{"id":"T15938","span":{"begin":206,"end":214},"obj":"Protein"},{"id":"T15937","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T15936","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T15935","span":{"begin":87,"end":92},"obj":"Protein"}],"relations":[{"id":"R11747","pred":"themeOf","subj":"T15934","obj":"T15942"},{"id":"R11748","pred":"themeOf","subj":"T15934","obj":"T15945"},{"id":"R11749","pred":"themeOf","subj":"T15934","obj":"T15946"},{"id":"R11750","pred":"themeOf","subj":"T15935","obj":"T15942"},{"id":"R11751","pred":"causeOf","subj":"T15937","obj":"T15943"},{"id":"R11752","pred":"causeOf","subj":"T15937","obj":"T15943"},{"id":"R11753","pred":"themeOf","subj":"T15938","obj":"T15943"},{"id":"R11754","pred":"themeOf","subj":"T15938","obj":"T15944"},{"id":"R11755","pred":"themeOf","subj":"T15944","obj":"T15943"},{"id":"R11756","pred":"themeOf","subj":"T15946","obj":"T15942"},{"id":"R11757","pred":"themeOf","subj":"T15946","obj":"T15945"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T16025","span":{"begin":181,"end":189},"obj":"Positive_regulation"},{"id":"T16024","span":{"begin":74,"end":83},"obj":"Positive_regulation"},{"id":"T16023","span":{"begin":105,"end":114},"obj":"Negative_regulation"},{"id":"T16022","span":{"begin":194,"end":205},"obj":"Positive_regulation"},{"id":"T16019","span":{"begin":206,"end":214},"obj":"Protein"},{"id":"T16018","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T16017","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T16016","span":{"begin":87,"end":92},"obj":"Protein"},{"id":"T16015","span":{"begin":29,"end":37},"obj":"Protein"}],"relations":[{"id":"R11775","pred":"themeOf","subj":"T16016","obj":"T16024"},{"id":"R11776","pred":"themeOf","subj":"T16017","obj":"T16023"},{"id":"R11777","pred":"causeOf","subj":"T16018","obj":"T16025"},{"id":"R11778","pred":"themeOf","subj":"T16019","obj":"T16025"},{"id":"R11779","pred":"themeOf","subj":"T16019","obj":"T16022"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"DLUT931","denotations":[{"id":"T15985","span":{"begin":194,"end":205},"obj":"Positive_regulation"},{"id":"T15984","span":{"begin":105,"end":114},"obj":"Negative_regulation"},{"id":"T15983","span":{"begin":74,"end":83},"obj":"Positive_regulation"},{"id":"T15978","span":{"begin":206,"end":214},"obj":"Protein"},{"id":"T15977","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T15976","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T15975","span":{"begin":87,"end":92},"obj":"Protein"},{"id":"T15974","span":{"begin":29,"end":37},"obj":"Protein"}],"relations":[{"id":"R11763","pred":"themeOf","subj":"T15974","obj":"T15983"},{"id":"R11764","pred":"themeOf","subj":"T15974","obj":"T15984"},{"id":"R11765","pred":"themeOf","subj":"T15978","obj":"T15985"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T16104","span":{"begin":14,"end":55},"obj":"Positive_regulation"},{"id":"T16095","span":{"begin":224,"end":232},"obj":"Entity"},{"id":"T16090","span":{"begin":96,"end":100},"obj":"Protein"},{"id":"T16089","span":{"begin":133,"end":136},"obj":"Protein"},{"id":"T16087","span":{"begin":14,"end":28},"obj":"Entity"},{"id":"T16086","span":{"begin":29,"end":37},"obj":"Protein"},{"id":"T16084","span":{"begin":154,"end":177},"obj":"Protein"},{"id":"T16083","span":{"begin":127,"end":131},"obj":"Protein"},{"id":"T16081","span":{"begin":194,"end":241},"obj":"Protein"},{"id":"T16079","span":{"begin":194,"end":205},"obj":"Entity"},{"id":"T16077","span":{"begin":29,"end":46},"obj":"Entity"},{"id":"T16076","span":{"begin":118,"end":124},"obj":"Protein"}],"relations":[{"id":"R11802","pred":"partOf","subj":"T16077","obj":"T16086"},{"id":"R11803","pred":"causeOf","subj":"T16087","obj":"T16104"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T16048","span":{"begin":181,"end":189},"obj":"Positive_regulation"},{"id":"T16047","span":{"begin":105,"end":114},"obj":"Negative_regulation"},{"id":"T16046","span":{"begin":74,"end":83},"obj":"Positive_regulation"},{"id":"T16045","span":{"begin":206,"end":232},"obj":"Protein"},{"id":"T16044","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T16043","span":{"begin":87,"end":100},"obj":"Protein"},{"id":"T16042","span":{"begin":29,"end":46},"obj":"Protein"}],"relations":[{"id":"R11786","pred":"themeOf","subj":"T16042","obj":"T16047"},{"id":"R11787","pred":"themeOf","subj":"T16043","obj":"T16046"},{"id":"R11788","pred":"causeOf","subj":"T16044","obj":"T16048"},{"id":"R11789","pred":"themeOf","subj":"T16045","obj":"T16048"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"testone","denotations":[{"id":"T15670","span":{"begin":105,"end":114},"obj":"Negative_regulation"},{"id":"T15663","span":{"begin":206,"end":214},"obj":"Protein"},{"id":"T15662","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T15661","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T15660","span":{"begin":87,"end":92},"obj":"Protein"},{"id":"T15659","span":{"begin":29,"end":37},"obj":"Protein"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}

{"project":"test3","denotations":[{"id":"T15686","span":{"begin":206,"end":214},"obj":"Protein"},{"id":"T15685","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T15684","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T15683","span":{"begin":87,"end":92},"obj":"Protein"},{"id":"T15682","span":{"begin":29,"end":37},"obj":"Protein"},{"id":"T15709","span":{"begin":206,"end":214},"obj":"Protein"},{"id":"T15708","span":{"begin":198,"end":205},"obj":"Positive_regulation"},{"id":"T15707","span":{"begin":170,"end":177},"obj":"Protein"},{"id":"T15706","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T15705","span":{"begin":87,"end":92},"obj":"Protein"},{"id":"T15704","span":{"begin":29,"end":37},"obj":"Protein"},{"id":"T15703","span":{"begin":18,"end":28},"obj":"Positive_regulation"}],"text":"We found that LPS-stimulated SerpinB2 promoter activity was significantly increased in Cebpb+/+ MEFs and abrogated in Cebpb−/− MEFs (Fig. 8A), indicating that endogenous C/EBP-β is required for LPS-induced SerpinB2 proximal promoter activity."}