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bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T24139 1855-1856 . denotes .
T24138 1844-1855 NNS denotes experiments
T24137 1832-1843 JJ denotes independent
T24136 1830-1831 CD denotes 7
T24135 1828-1829 CD denotes 4
T24134 1825-1827 IN denotes of
T24133 1821-1824 NNP denotes SEM
T24132 1817-1820 CC denotes and
T24071 1469-1470 , denotes ,
T24070 1462-1469 NNS denotes primers
T24069 1444-1461 JJ denotes promoter-specific
T24131 1812-1816 NN denotes mean
T24130 1808-1811 DT denotes the
T24129 1798-1807 VB denotes represent
T24128 1794-1797 CC denotes and
T24127 1784-1793 NN denotes treatment
T24126 1780-1783 NNP denotes LPS
T24125 1770-1779 VBG denotes following
T24124 1761-1769 NN denotes activity
T24123 1750-1760 NN denotes luciferase
T24122 1741-1749 JJ denotes relative
T24121 1736-1740 VBP denotes show
T24120 1728-1735 NNS denotes results
T24119 1724-1727 DT denotes The
T24118 1722-1723 . denotes .
T24117 1719-1722 NNS denotes hrs
T24116 1716-1718 CD denotes 16
T24115 1712-1715 IN denotes for
T24114 1708-1711 NNP denotes LPS
T24113 1702-1707 JJ denotes ng/ml
T24112 1698-1701 CD denotes 100
T24111 1693-1697 IN denotes with
T24110 1685-1692 VBN denotes treated
T24109 1682-1684 CC denotes or
T24108 1672-1681 JJ denotes untreated
T24107 1667-1671 VBD denotes left
T24106 1660-1666 RB denotes either
T24105 1656-1659 CC denotes and
T24104 1645-1655 NNS denotes constructs
T24103 1636-1644 NN denotes reporter
T24102 1616-1635 JJ denotes promoter-luciferase
T24101 1607-1615 NNP denotes SerpinB2
T24100 1600-1606 NN denotes murine
T24099 1590-1599 VBN denotes indicated
T24098 1586-1589 DT denotes the
T24097 1581-1585 IN denotes with
T24096 1569-1580 VBN denotes transfected
T24095 1557-1568 RB denotes transiently
T24094 1552-1556 VBD denotes were
T24093 1540-1551 NNS denotes macrophages
T24092 1534-1539 CD denotes 264.7
T24091 1530-1533 NNP denotes RAW
T24090 1528-1529 -RRB- denotes )
T24089 1527-1528 NNP denotes B
T24088 1526-1527 -LRB- denotes (
T24087 1524-1525 . denotes .
T24086 1515-1524 VBN denotes indicated
T24085 1511-1514 VBP denotes are
T24084 1504-1510 NNS denotes assays
T24083 1499-1503 NNP denotes ChIP
T24082 1496-1498 IN denotes in
T24081 1491-1495 VBN denotes used
T24080 1487-1490 CD denotes +19
T24079 1486-1487 NN denotes /
T24078 1485-1486 CD denotes 5
T24077 1484-1485 CD denotes −
T24076 1480-1483 CC denotes and
T24075 1476-1479 CD denotes 315
T24074 1475-1476 NN denotes −
T24073 1474-1475 CD denotes /
T24072 1471-1474 CD denotes 338
T24068 1435-1443 JJ denotes proximal
T24067 1426-1434 CD denotes SerpinB2
T24066 1419-1425 NN denotes murine
T24065 1416-1418 IN denotes of
T24064 1406-1415 NNS denotes Positions
T24063 1404-1405 . denotes .
T24062 1399-1404 VBN denotes shown
T24061 1394-1398 RB denotes also
T24060 1391-1393 VBZ denotes is
T24059 1380-1390 NNS denotes constructs
T24058 1371-1379 NN denotes reporter
T24057 1368-1370 CD denotes 87
T24056 1367-1368 CD denotes −
T24055 1363-1366 CC denotes and
T24054 1359-1362 CD denotes 189
T24053 1358-1359 CD denotes −
T24052 1356-1357 , denotes ,
T24051 1353-1356 CD denotes 539
T24050 1352-1353 NN denotes −
T24049 1348-1351 DT denotes the
T24048 1345-1347 IN denotes of
T24047 1340-1344 NNS denotes ends
T24046 1338-1339 NN denotes ′
T24045 1337-1338 CD denotes 5
T24044 1333-1336 DT denotes the
T24043 1330-1332 IN denotes of
T24042 1321-1329 NN denotes location
T24041 1317-1320 DT denotes The
T24040 1315-1316 . denotes .
T24039 1310-1315 NNS denotes boxes
T24038 1305-1309 IN denotes with
T24037 1295-1304 VBD denotes indicated
T24036 1286-1294 NNS denotes elements
T24035 1275-1285 JJ denotes regulatory
T24034 1264-1274 JJ denotes cis-acting
T24033 1254-1263 NN denotes candidate
T24032 1251-1253 IN denotes of
T24031 1242-1250 NN denotes location
T24030 1238-1241 DT denotes the
T24029 1233-1237 IN denotes with
T24028 1224-1232 NN denotes promoter
T24027 1215-1223 NNP denotes SerpinB2
T24026 1208-1214 NN denotes murine
T24025 1204-1207 DT denotes the
T24024 1201-1203 IN denotes of
T24023 1194-1200 NN denotes region
T24022 1190-1193 CD denotes +92
T24021 1189-1190 NN denotes /
T24020 1186-1189 CD denotes 539
T24019 1185-1186 NN denotes −
T24018 1181-1184 DT denotes the
T24017 1178-1180 IN denotes of
T24016 1163-1177 NN denotes representation
T24015 1153-1162 JJ denotes Schematic
T24014 1151-1152 -RRB- denotes )
T24013 1150-1151 NN denotes A
T24012 1149-1150 -LRB- denotes (
T24011 1147-1148 . denotes .
T24010 1139-1147 NN denotes promoter
T24009 1130-1138 NNP denotes SerpinB2
T24008 1123-1129 NN denotes murine
T24007 1119-1122 DT denotes the
T24006 1116-1118 IN denotes of
T24005 1097-1115 NN denotes LPS-responsiveness
T24004 1093-1096 DT denotes the
T24003 1089-1092 IN denotes for
T24002 1080-1088 VBN denotes required
T24001 1071-1079 NNS denotes elements
T24000 1060-1070 JJ denotes cis-acting
T23999 1057-1059 IN denotes of
T23998 1042-1056 NN denotes Identification
T12297 2261-2262 CD denotes −
T12296 2258-2260 IN denotes at
T12295 2254-2257 NNP denotes CRE
T12294 2250-2253 DT denotes the
T12293 2247-2249 IN denotes of
T12292 2238-2246 NN denotes mutation
T12291 2236-2237 , denotes ,
T12290 2234-2236 NNP denotes 4B
T12289 2229-2233 NNP denotes Fig.
T12288 2226-2228 IN denotes in
T12287 2220-2225 VBN denotes shown
T12286 2217-2219 IN denotes As
T12285 2215-2216 . denotes .
T12284 2207-2215 NN denotes promoter
T12283 2198-2206 NNP denotes SerpinB2
T12282 2191-2197 NN denotes murine
T12281 2187-2190 DT denotes the
T12280 2184-2186 IN denotes of
T12279 2175-2183 NN denotes response
T12278 2171-2174 NNP denotes LPS
T12277 2167-2170 DT denotes the
T12276 2164-2166 IN denotes in
T12275 2159-2163 NN denotes role
T12274 2157-2158 DT denotes a
T12273 2150-2156 VBD denotes played
T12272 2145-2149 PRP denotes they
T12271 2137-2144 IN denotes whether
T12270 2125-2136 VB denotes investigate
T12269 2122-2124 TO denotes to
T12268 2109-2121 NN denotes substitution
T12267 2098-2108 NN denotes nucleotide
T12266 2095-2097 IN denotes by
T12265 2087-2094 VBN denotes mutated
T12264 2082-2086 RB denotes also
T12263 2077-2081 VBD denotes were
T12262 2071-2076 NNS denotes sites
T12261 2065-2070 DT denotes these
T12260 2063-2064 , denotes ,
T12259 2062-2063 NNP denotes ]
T12258 2060-2062 CD denotes 37
T12257 2059-2060 NNP denotes [
T12256 2050-2058 NN denotes promoter
T12255 2041-2049 NNP denotes SERPINB2
T12254 2035-2040 JJ denotes human
T12253 2031-2034 DT denotes the
T12252 2028-2030 IN denotes of
T12251 2009-2027 NN denotes PMA-responsiveness
T12250 2005-2008 DT denotes the
T12249 2002-2004 IN denotes in
T12248 1990-2001 NN denotes involvement
T12247 1977-1989 VBN denotes demonstrated
T12246 1971-1976 PRP$ denotes their
T12245 1967-1970 CC denotes and
T12244 1958-1966 NN denotes promoter
T12243 1949-1957 NNP denotes SerpinB2
T12242 1942-1948 NN denotes murine
T12241 1938-1941 DT denotes the
T12240 1935-1937 IN denotes in
T12239 1929-1934 NNS denotes sites
T12238 1924-1928 JJ denotes AP-1
T12237 1920-1923 CD denotes two
T12236 1916-1919 CC denotes and
T12235 1912-1915 NNP denotes CRE
T12234 1908-1911 DT denotes the
T12233 1905-1907 IN denotes of
T12232 1896-1904 NN denotes position
T12231 1892-1895 CC denotes and
T12230 1883-1891 NN denotes sequence
T12229 1873-1882 JJ denotes conserved
T12228 1869-1872 DT denotes the
T12227 1857-1868 VBG denotes Considering
T12226 996-997 . denotes .
T12225 995-996 NNP denotes ]
T12224 993-995 CD denotes 58
T12223 992-993 NNP denotes [
T12222 987-991 NN denotes gene
T12221 978-986 NNP denotes SerpinB2
T12220 974-977 DT denotes the
T12219 971-973 IN denotes of
T12218 960-970 NN denotes activation
T12217 948-959 JJ denotes LPS-induced
T12216 945-947 IN denotes in
T12215 940-944 NN denotes site
T12214 934-939 NNP denotes C/EBP
T12213 929-933 DT denotes this
T12212 918-928 VBN denotes implicated
T12211 909-917 RB denotes recently
T12210 904-908 RB denotes also
T12209 899-903 VBP denotes have
T12208 892-898 NNS denotes Others
T12207 890-891 . denotes .
T12206 881-890 VBP denotes construct
T12205 872-880 NN denotes deletion
T12204 863-871 NN denotes promoter
T12203 854-862 CD denotes SerpinB2
T12202 850-853 CD denotes 189
T12201 849-850 NN denotes −
T12200 845-848 DT denotes the
T12199 841-844 IN denotes for
T12198 832-840 VBD denotes observed
T12197 825-831 NNS denotes levels
T12196 821-824 DT denotes the
T12195 818-820 TO denotes to
T12194 810-817 JJ denotes similar
T12193 808-809 , denotes ,
T12192 800-808 NN denotes activity
T12191 791-799 NN denotes promoter
T12190 780-790 VBN denotes eliminated
T12189 769-779 RB denotes completely
T12188 767-768 -RRB- denotes )
T12187 764-767 CD denotes 192
T12186 763-764 NN denotes −
T12185 762-763 CD denotes /
T12184 759-762 CD denotes 203
T12183 758-759 FW denotes −
T12182 757-758 -LRB- denotes (
T12181 752-756 NN denotes site
T12180 746-751 NNP denotes C/EBP
T12179 742-745 DT denotes the
T12178 739-741 IN denotes of
T12177 730-738 NN denotes mutation
T12176 728-729 , denotes ,
T12175 720-728 NN denotes contrast
T12174 717-719 IN denotes In
T12173 715-716 . denotes .
T12172 707-715 NN denotes activity
T12171 698-706 NN denotes promoter
T12170 686-697 JJ denotes LPS-induced
T12169 677-685 VB denotes decrease
T12168 673-676 RB denotes not
T12167 669-672 VBD denotes did
T12166 664-668 NN denotes site
T12165 662-663 -RRB- denotes )
T12164 659-662 CD denotes 288
T12163 658-659 NN denotes −
T12162 657-658 CD denotes /
T12161 654-657 CD denotes 296
T12160 653-654 FW denotes −
T12159 652-653 -LRB- denotes (
T12158 646-651 NN denotes Oct-1
T12157 638-645 JJ denotes variant
T12156 634-637 DT denotes the
T12155 631-633 CC denotes or
T12154 629-630 , denotes ,
T12153 628-629 -RRB- denotes )
T12152 625-628 CD denotes 407
T12151 624-625 NN denotes −
T12150 623-624 CD denotes /
T12149 620-623 CD denotes 412
T12148 619-620 NN denotes −
T12147 618-619 -LRB- denotes (
T12146 615-617 CD denotes .1
T12145 613-615 NNP denotes PU
T12144 611-612 , denotes ,
T12143 610-611 -RRB- denotes )
T12142 607-610 CD denotes 533
T12141 606-607 NN denotes −
T12140 605-606 CD denotes /
T12139 602-605 CD denotes 538
T12138 601-602 FW denotes −
T12137 600-601 -LRB- denotes (
T12136 596-599 NN denotes box
T12135 594-595 NNP denotes E
T12134 584-593 NN denotes consensus
T12133 580-583 DT denotes the
T12132 577-579 IN denotes of
T12131 568-576 NN denotes mutation
T12130 566-567 , denotes ,
T12129 564-566 NNP denotes 4B
T12128 559-563 NNP denotes Fig.
T12127 556-558 IN denotes in
T12126 550-555 VBN denotes shown
T12125 547-549 IN denotes As
T12124 545-546 . denotes .
T12123 544-545 -RRB- denotes )
T12122 542-544 NNP denotes 4A
T12121 537-541 NNP denotes Fig.
T12120 536-537 -LRB- denotes (
T12119 526-535 VBP denotes construct
T12118 521-525 NN denotes gene
T12117 512-520 NN denotes reporter
T12116 492-511 JJ denotes promoter-luciferase
T12115 483-491 NNP denotes SerpinB2
T12114 476-482 NN denotes murine
T12113 466-475 JJ denotes pGLmP-539
T12112 462-465 DT denotes the
T12111 459-461 TO denotes to
T12110 451-458 JJ denotes binding
T12109 444-450 NN denotes factor
T12108 430-443 NN denotes transcription
T12107 422-429 VB denotes disrupt
T12106 419-421 TO denotes to
T12105 410-418 VBN denotes designed
T12104 397-409 NN denotes substitution
T12103 386-396 NN denotes nucleotide
T12102 383-385 IN denotes by
T12101 374-382 VBN denotes targeted
T12100 369-373 VBD denotes were
T12099 367-368 NNP denotes ]
T12098 365-367 CD denotes 57
T12097 364-365 NNP denotes [
T12096 358-363 NNS denotes genes
T12095 352-357 JJ denotes other
T12094 349-351 IN denotes in
T12093 335-348 NN denotes transcription
T12092 321-334 JJ denotes LPS-inducible
T12091 313-320 VB denotes mediate
T12090 310-312 TO denotes to
T12089 301-309 VBD denotes reported
T12088 290-300 RB denotes previously
T12087 282-289 NNS denotes factors
T12086 268-281 NN denotes transcription
T12085 264-267 IN denotes for
T12084 258-263 NNS denotes sites
T12083 250-257 JJ denotes binding
T12082 240-249 NN denotes candidate
T12363 2607-2608 . denotes .
T12362 2599-2607 NN denotes promoter
T12361 2590-2598 JJ denotes proximal
T12360 2581-2589 NNP denotes SerpinB2
T12359 2577-2580 DT denotes the
T12358 2572-2576 IN denotes from
T12357 2558-2571 NN denotes transcription
T12356 2544-2557 JJ denotes LPS-inducible
T12355 2540-2543 IN denotes for
T12354 2531-2539 JJ denotes critical
T12353 2527-2530 VBP denotes are
T12352 2518-2526 NNS denotes elements
T12351 2507-2517 JJ denotes cis-acting
T12350 2502-2506 JJ denotes AP-1
T12349 2497-2501 DT denotes both
T12348 2493-2496 CC denotes and
T12347 2489-2492 NNP denotes CRE
T12346 2485-2488 DT denotes the
T12345 2482-2484 IN denotes as
T12344 2477-2481 RB denotes well
T12343 2474-2476 RB denotes as
T12342 2472-2473 , denotes ,
T12341 2465-2472 NN denotes element
T12340 2459-2464 NNP denotes C/EBP
T12339 2455-2458 DT denotes the
T12338 2450-2454 IN denotes that
T12337 2445-2449 VBP denotes show
T12336 2440-2444 NNS denotes data
T12335 2434-2439 DT denotes These
T12334 2432-2433 . denotes .
T12333 2424-2432 NN denotes promoter
T12332 2415-2423 NNP denotes SerpinB2
T12331 2408-2414 NN denotes murine
T12330 2404-2407 DT denotes the
T12329 2399-2403 IN denotes from
T12328 2390-2398 NN denotes activity
T12327 2379-2389 NN denotes luciferase
T12326 2365-2378 JJ denotes LPS-inducible
T12325 2357-2364 VBN denotes reduced
T12324 2343-2356 RB denotes significantly
T12323 2340-2342 CC denotes or
T12322 2329-2339 RB denotes completely
T12321 2327-2328 , denotes ,
T12320 2325-2327 CD denotes 88
T12319 2324-2325 NN denotes −
T12318 2323-2324 NN denotes /
T12317 2321-2323 CD denotes 94
T12316 2320-2321 CD denotes −
T12315 2316-2319 CC denotes and
T12314 2312-2315 CD denotes 100
T12313 2311-2312 NN denotes −
T12312 2310-2311 NN denotes /
T12311 2307-2310 CD denotes 106
T12310 2306-2307 CD denotes −
T12309 2303-2305 IN denotes at
T12308 2297-2302 NNS denotes sites
T12307 2292-2296 JJ denotes AP-1
T12306 2288-2291 CD denotes two
T12305 2284-2287 DT denotes the
T12304 2281-2283 IN denotes of
T12303 2274-2280 DT denotes either
T12302 2271-2273 CC denotes or
T12301 2267-2270 CD denotes 172
T12300 2266-2267 NN denotes −
T12299 2265-2266 NN denotes /
T12298 2262-2265 CD denotes 177
T12081 232-239 JJ denotes several
T12080 230-231 , denotes ,
T12079 217-230 NN denotes transcription
T12078 203-216 JJ denotes LPS-inducible
T12077 199-202 IN denotes for
T12076 189-198 JJ denotes essential
T12075 185-188 CD denotes 189
T12074 184-185 CD denotes −
T12073 180-183 CC denotes and
T12072 176-179 CD denotes 539
T12071 175-176 CD denotes −
T12070 167-174 IN denotes between
T12069 158-166 NNS denotes elements
T12068 147-157 JJ denotes regulatory
T12067 135-146 VB denotes investigate
T12066 132-134 TO denotes To
T12065 118-131 NNP denotes Transcription
T12064 104-117 NNP denotes LPS-inducible
T12063 96-103 NNP denotes Optimal
T12062 92-95 IN denotes for
T12061 82-91 JJ denotes Essential
T12060 78-81 VBP denotes are
T12059 69-77 NNP denotes Promoter
T12058 60-68 NNP denotes Proximal
T12057 55-59 NNP denotes Gene
T12056 46-54 NNP denotes SerpinB2
T12055 39-45 NNP denotes Murine
T12054 35-38 DT denotes the
T12053 32-34 IN denotes in
T12052 26-31 NNS denotes Sites
T12051 21-25 JJ denotes AP-1
T12050 17-20 CD denotes Two
T12049 13-16 CC denotes and
T12048 9-12 NNP denotes CRE
T12047 7-8 , denotes ,
T12046 2-7 NNP denotes C/EBP
T12045 0-1 DT denotes A
R8845 T12045 T12052 det A,Sites
R8846 T12046 T12052 nmod C/EBP,Sites
R8847 T12047 T12046 punct ",",C/EBP
R8848 T12048 T12046 conj CRE,C/EBP
R8849 T12049 T12048 cc and,CRE
R8850 T12050 T12052 nummod Two,Sites
R8851 T12051 T12052 amod AP-1,Sites
R8852 T12052 T12052 ROOT Sites,Sites
R8853 T12053 T12052 prep in,Sites
R8854 T12054 T12056 det the,SerpinB2
R8855 T12055 T12056 compound Murine,SerpinB2
R8856 T12056 T12053 pobj SerpinB2,in
R8857 T12057 T12058 compound Gene,Proximal
R8858 T12058 T12056 appos Proximal,SerpinB2
R8859 T12059 T12060 nsubj Promoter,are
R8860 T12060 T12060 ROOT are,are
R8861 T12061 T12060 acomp Essential,are
R8862 T12062 T12067 mark for,investigate
R8863 T12063 T12065 compound Optimal,Transcription
R8864 T12064 T12065 compound LPS-inducible,Transcription
R8865 T12065 T12067 nsubj Transcription,investigate
R8866 T12066 T12067 aux To,investigate
R8867 T12067 T12101 advcl investigate,targeted
R8868 T12068 T12069 amod regulatory,elements
R8869 T12069 T12067 dobj elements,investigate
R8870 T12070 T12069 prep between,elements
R8871 T12071 T12070 pobj −,between
R8872 T12072 T12071 conj 539,−
R8873 T12073 T12072 cc and,539
R8874 T12074 T12072 conj −,539
R8875 T12075 T12076 nummod 189,essential
R8876 T12076 T12071 conj essential,−
R8877 T12077 T12076 prep for,essential
R8878 T12078 T12079 amod LPS-inducible,transcription
R8879 T12079 T12077 pobj transcription,for
R8880 T12080 T12069 punct ",",elements
R8881 T12081 T12084 amod several,sites
R8882 T12082 T12084 nmod candidate,sites
R8883 T12083 T12084 amod binding,sites
R8884 T12084 T12069 conj sites,elements
R8885 T12085 T12084 prep for,sites
R8886 T12086 T12087 compound transcription,factors
R8887 T12087 T12085 pobj factors,for
R8888 T12088 T12089 advmod previously,reported
R8889 T12089 T12067 conj reported,investigate
R8890 T12090 T12091 aux to,mediate
R8891 T12091 T12089 xcomp mediate,reported
R8892 T12092 T12093 compound LPS-inducible,transcription
R8893 T12093 T12091 dobj transcription,mediate
R8894 T12094 T12093 prep in,transcription
R8895 T12095 T12096 amod other,genes
R8896 T12096 T12094 pobj genes,in
R8897 T12097 T12099 nmod [,]
R8898 T12098 T12099 nummod 57,]
R8899 T12099 T12101 nsubjpass ],targeted
R8900 T12100 T12101 auxpass were,targeted
R8901 T12101 T12101 ROOT targeted,targeted
R8902 T12102 T12101 agent by,targeted
R8903 T12103 T12104 compound nucleotide,substitution
R8904 T12104 T12102 pobj substitution,by
R8905 T12105 T12104 acl designed,substitution
R8906 T12106 T12107 aux to,disrupt
R8907 T12107 T12105 xcomp disrupt,designed
R8908 T12108 T12109 compound transcription,factor
R8909 T12109 T12107 dobj factor,disrupt
R8910 T12110 T12107 advmod binding,disrupt
R8911 T12111 T12110 prep to,binding
R8912 T12112 T12118 det the,gene
R8913 T12113 T12118 amod pGLmP-539,gene
R8914 T12114 T12118 nmod murine,gene
R8915 T12115 T12118 nmod SerpinB2,gene
R8916 T12116 T12118 amod promoter-luciferase,gene
R8917 T12117 T12118 compound reporter,gene
R8918 T12118 T12111 pobj gene,to
R8919 T12119 T12101 csubj construct,targeted
R8920 T12120 T12101 punct (,targeted
R8921 T12121 T12122 compound Fig.,4A
R8922 T12122 T12101 appos 4A,targeted
R8923 T12123 T12101 punct ),targeted
R8924 T12124 T12060 punct .,are
R8925 T12125 T12126 mark As,shown
R8926 T12126 T12169 advcl shown,decrease
R8927 T12127 T12126 prep in,shown
R8928 T12128 T12129 compound Fig.,4B
R8929 T12129 T12127 pobj 4B,in
R8930 T12130 T12129 punct ",",4B
R8931 T12131 T12129 appos mutation,4B
R8932 T12132 T12131 prep of,mutation
R8933 T12133 T12136 det the,box
R8934 T12134 T12136 compound consensus,box
R8935 T12135 T12136 compound E,box
R8936 T12136 T12132 pobj box,of
R8937 T12137 T12136 punct (,box
R8938 T12138 T12169 dep −,decrease
R8939 T12139 T12169 dep 538,decrease
R8940 T12140 T12169 dep /,decrease
R8941 T12141 T12169 dep −,decrease
R8942 T12142 T12141 nummod 533,−
R8943 T12143 T12141 punct ),−
R8944 T12144 T12146 punct ",",.1
R8945 T12145 T12146 compound PU,.1
R8946 T12146 T12141 appos .1,−
R8947 T12147 T12169 punct (,decrease
R8948 T12148 T12169 nsubj −,decrease
R8949 T12149 T12169 dep 412,decrease
R8950 T12150 T12169 dep /,decrease
R8951 T12151 T12169 nsubj −,decrease
R8952 T12152 T12151 nummod 407,−
R8953 T12153 T12151 punct ),−
R8954 T12154 T12151 punct ",",−
R8955 T12155 T12151 cc or,−
R8956 T12156 T12158 det the,Oct-1
R8957 T12157 T12158 compound variant,Oct-1
R8958 T12158 T12151 conj Oct-1,−
R8959 T12159 T12158 punct (,Oct-1
R8960 T12160 T12166 nmod −,site
R8961 T12161 T12162 compound 296,/
R8962 T12162 T12166 nummod /,site
R8963 T12163 T12166 nmod −,site
R8964 T12164 T12163 nummod 288,−
R8965 T12165 T12163 punct ),−
R8966 T12166 T12158 appos site,Oct-1
R8967 T12167 T12169 aux did,decrease
R8968 T12168 T12169 neg not,decrease
R8969 T12169 T12169 ROOT decrease,decrease
R8970 T12170 T12172 amod LPS-induced,activity
R8971 T12171 T12172 compound promoter,activity
R8972 T12172 T12169 dobj activity,decrease
R8973 T12173 T12169 punct .,decrease
R8974 T12174 T12206 prep In,construct
R8975 T12175 T12174 pobj contrast,In
R8976 T12176 T12206 punct ",",construct
R8977 T12177 T12206 nsubj mutation,construct
R8978 T12178 T12177 prep of,mutation
R8979 T12179 T12181 det the,site
R8980 T12180 T12181 compound C/EBP,site
R8981 T12181 T12178 pobj site,of
R8982 T12182 T12181 punct (,site
R8983 T12183 T12206 dep −,construct
R8984 T12184 T12206 nummod 203,construct
R8985 T12185 T12206 nummod /,construct
R8986 T12186 T12206 npadvmod −,construct
R8987 T12187 T12186 nummod 192,−
R8988 T12188 T12186 punct ),−
R8989 T12189 T12190 advmod completely,eliminated
R8990 T12190 T12206 amod eliminated,construct
R8991 T12191 T12192 compound promoter,activity
R8992 T12192 T12190 dobj activity,eliminated
R8993 T12193 T12192 punct ",",activity
R8994 T12194 T12192 amod similar,activity
R8995 T12195 T12194 prep to,similar
R8996 T12196 T12197 det the,levels
R8997 T12197 T12195 pobj levels,to
R8998 T12198 T12197 acl observed,levels
R8999 T12199 T12198 prep for,observed
R9000 T12200 T12205 det the,deletion
R9001 T12201 T12205 nmod −,deletion
R9002 T12202 T12201 nummod 189,−
R9003 T12203 T12205 nummod SerpinB2,deletion
R9004 T12204 T12205 compound promoter,deletion
R9005 T12205 T12199 pobj deletion,for
R9006 T12206 T12206 ROOT construct,construct
R9007 T12207 T12206 punct .,construct
R9008 T12208 T12212 nsubj Others,implicated
R9009 T12209 T12212 aux have,implicated
R9010 T12210 T12212 advmod also,implicated
R9011 T12211 T12212 advmod recently,implicated
R9012 T12212 T12212 ROOT implicated,implicated
R9013 T12213 T12215 det this,site
R9014 T12214 T12215 compound C/EBP,site
R9015 T12215 T12212 dobj site,implicated
R9016 T12216 T12212 prep in,implicated
R9017 T12217 T12218 amod LPS-induced,activation
R9018 T12218 T12216 pobj activation,in
R9019 T12219 T12218 prep of,activation
R9020 T12220 T12222 det the,gene
R9021 T12221 T12222 compound SerpinB2,gene
R9022 T12222 T12219 pobj gene,of
R9023 T12223 T12225 nmod [,]
R9024 T12224 T12225 nummod 58,]
R9025 T12225 T12212 npadvmod ],implicated
R9026 T12226 T12212 punct .,implicated
R9027 T12227 T12265 advcl Considering,mutated
R9028 T12228 T12230 det the,sequence
R9029 T12229 T12230 amod conserved,sequence
R9030 T12230 T12227 dobj sequence,Considering
R9031 T12231 T12230 cc and,sequence
R9032 T12232 T12230 conj position,sequence
R9033 T12233 T12232 prep of,position
R9034 T12234 T12235 det the,CRE
R9035 T12235 T12233 pobj CRE,of
R9036 T12236 T12232 cc and,position
R9037 T12237 T12239 nummod two,sites
R9038 T12238 T12239 amod AP-1,sites
R9039 T12239 T12232 conj sites,position
R9040 T12240 T12239 prep in,sites
R9041 T12241 T12244 det the,promoter
R9042 T12242 T12244 compound murine,promoter
R9043 T12243 T12244 compound SerpinB2,promoter
R9044 T12244 T12240 pobj promoter,in
R9045 T12245 T12244 cc and,promoter
R9046 T12246 T12248 poss their,involvement
R9047 T12247 T12248 amod demonstrated,involvement
R9048 T12248 T12232 conj involvement,position
R9049 T12249 T12248 prep in,involvement
R9050 T12250 T12251 det the,PMA-responsiveness
R9051 T12251 T12249 pobj PMA-responsiveness,in
R9052 T12252 T12251 prep of,PMA-responsiveness
R9053 T12253 T12256 det the,promoter
R9054 T12254 T12256 amod human,promoter
R9055 T12255 T12256 compound SERPINB2,promoter
R9056 T12256 T12252 pobj promoter,of
R9057 T12257 T12256 appos [,promoter
R9058 T12258 T12259 nummod 37,]
R9059 T12259 T12256 appos ],promoter
R9060 T12260 T12265 punct ",",mutated
R9061 T12261 T12262 det these,sites
R9062 T12262 T12265 nsubjpass sites,mutated
R9063 T12263 T12265 auxpass were,mutated
R9064 T12264 T12265 advmod also,mutated
R9065 T12265 T12265 ROOT mutated,mutated
R9066 T12266 T12265 agent by,mutated
R9067 T12267 T12268 compound nucleotide,substitution
R9068 T12268 T12266 pobj substitution,by
R9069 T12269 T12270 aux to,investigate
R9070 T12270 T12265 advcl investigate,mutated
R9071 T12271 T12273 mark whether,played
R9072 T12272 T12273 nsubj they,played
R9073 T12273 T12270 ccomp played,investigate
R9074 T12274 T12275 det a,role
R9075 T12275 T12273 dobj role,played
R9076 T12276 T12275 prep in,role
R9077 T12277 T12279 det the,response
R9078 T12278 T12279 compound LPS,response
R9079 T12279 T12276 pobj response,in
R9080 T12280 T12279 prep of,response
R9081 T12281 T12284 det the,promoter
R9082 T12282 T12284 compound murine,promoter
R9083 T12283 T12284 compound SerpinB2,promoter
R9084 T12284 T12280 pobj promoter,of
R9085 T12285 T12265 punct .,mutated
R9086 T12286 T12287 mark As,shown
R9087 T12287 T12325 advcl shown,reduced
R9088 T12288 T12287 prep in,shown
R9089 T12289 T12290 compound Fig.,4B
R9090 T12290 T12288 pobj 4B,in
R9091 T12291 T12290 punct ",",4B
R9092 T12292 T12290 appos mutation,4B
R9093 T12293 T12292 prep of,mutation
R9094 T12294 T12295 det the,CRE
R9095 T12295 T12293 pobj CRE,of
R9096 T12296 T12292 prep at,mutation
R9097 T12297 T12301 nummod −,172
R9098 T12298 T12300 nummod 177,−
R9099 T12299 T12300 compound /,−
R9100 T12300 T12301 nummod −,172
R9101 T12301 T12296 pobj 172,at
R9102 T12302 T12301 cc or,172
R9103 T12303 T12301 conj either,172
R9104 T12304 T12303 prep of,either
R9105 T12305 T12308 det the,sites
R9106 T12306 T12308 nummod two,sites
R9107 T12307 T12308 amod AP-1,sites
R9108 T12308 T12304 pobj sites,of
R9109 T12309 T12303 prep at,either
R9110 T12310 T12325 punct −,reduced
R9111 T12311 T12313 nummod 106,−
R9112 T12312 T12313 compound /,−
R9113 T12313 T12325 nsubj −,reduced
R9114 T12314 T12313 nummod 100,−
R9115 T12315 T12313 cc and,−
R9116 T12316 T12319 meta −,−
R9117 T12317 T12319 nummod 94,−
R9118 T12318 T12319 compound /,−
R9119 T12319 T12313 conj −,−
R9120 T12320 T12319 nummod 88,−
R9121 T12321 T12319 punct ",",−
R9122 T12322 T12325 advmod completely,reduced
R9123 T12323 T12322 cc or,completely
R9124 T12324 T12322 conj significantly,completely
R9125 T12325 T12325 ROOT reduced,reduced
R9126 T12326 T12328 amod LPS-inducible,activity
R9127 T12327 T12328 compound luciferase,activity
R9128 T12328 T12325 dobj activity,reduced
R9129 T12329 T12325 prep from,reduced
R9130 T12330 T12333 det the,promoter
R9131 T12331 T12333 compound murine,promoter
R9132 T12332 T12333 compound SerpinB2,promoter
R9133 T12333 T12329 pobj promoter,from
R9134 T12334 T12325 punct .,reduced
R9135 T12335 T12336 det These,data
R9136 T12336 T12337 nsubj data,show
R9137 T12337 T12337 ROOT show,show
R9138 T12338 T12353 mark that,are
R9139 T12339 T12341 det the,element
R9140 T12340 T12341 compound C/EBP,element
R9141 T12341 T12353 nsubj element,are
R9142 T12342 T12341 punct ",",element
R9143 T12343 T12345 advmod as,as
R9144 T12344 T12345 advmod well,as
R9145 T12345 T12341 cc as,element
R9146 T12346 T12347 det the,CRE
R9147 T12347 T12341 conj CRE,element
R9148 T12348 T12347 cc and,CRE
R9149 T12349 T12352 det both,elements
R9150 T12350 T12352 amod AP-1,elements
R9151 T12351 T12352 amod cis-acting,elements
R9152 T12352 T12347 conj elements,CRE
R9153 T12353 T12337 ccomp are,show
R9154 T12354 T12353 acomp critical,are
R9155 T12355 T12354 prep for,critical
R9156 T12356 T12357 amod LPS-inducible,transcription
R9157 T12357 T12355 pobj transcription,for
R9158 T12358 T12357 prep from,transcription
R9159 T12359 T12362 det the,promoter
R9160 T12360 T12362 nmod SerpinB2,promoter
R9161 T12361 T12362 amod proximal,promoter
R9162 T12362 T12358 pobj promoter,from
R9163 T12363 T12337 punct .,show
R17240 T23998 T23998 ROOT Identification,Identification
R17241 T23999 T23998 prep of,Identification
R17242 T24000 T24001 amod cis-acting,elements
R17243 T24001 T23999 pobj elements,of
R17244 T24002 T24001 acl required,elements
R17245 T24003 T24002 prep for,required
R17246 T24004 T24005 det the,LPS-responsiveness
R17247 T24005 T24003 pobj LPS-responsiveness,for
R17248 T24006 T24005 prep of,LPS-responsiveness
R17249 T24007 T24010 det the,promoter
R17250 T24008 T24010 compound murine,promoter
R17251 T24009 T24010 compound SerpinB2,promoter
R17252 T24010 T24006 pobj promoter,of
R17253 T24011 T23998 punct .,Identification
R17254 T24012 T24013 punct (,A
R17255 T24013 T24016 nmod A,representation
R17256 T24014 T24013 punct ),A
R17257 T24015 T24016 amod Schematic,representation
R17258 T24016 T24037 nsubj representation,indicated
R17259 T24017 T24016 prep of,representation
R17260 T24018 T24023 det the,region
R17261 T24019 T24023 nmod −,region
R17262 T24020 T24019 nummod 539,−
R17263 T24021 T24023 amod /,region
R17264 T24022 T24023 nummod +92,region
R17265 T24023 T24017 pobj region,of
R17266 T24024 T24023 prep of,region
R17267 T24025 T24028 det the,promoter
R17268 T24026 T24028 compound murine,promoter
R17269 T24027 T24028 compound SerpinB2,promoter
R17270 T24028 T24024 pobj promoter,of
R17271 T24029 T24028 prep with,promoter
R17272 T24030 T24031 det the,location
R17273 T24031 T24029 pobj location,with
R17274 T24032 T24031 prep of,location
R17275 T24033 T24036 nmod candidate,elements
R17276 T24034 T24036 amod cis-acting,elements
R17277 T24035 T24036 amod regulatory,elements
R17278 T24036 T24032 pobj elements,of
R17279 T24037 T24037 ROOT indicated,indicated
R17280 T24038 T24037 prep with,indicated
R17281 T24039 T24038 pobj boxes,with
R17282 T24040 T24037 punct .,indicated
R17283 T24041 T24042 det The,location
R17284 T24042 T24062 nsubjpass location,shown
R17285 T24043 T24042 prep of,location
R17286 T24044 T24047 det the,ends
R17287 T24045 T24046 nummod 5,′
R17288 T24046 T24047 compound ′,ends
R17289 T24047 T24043 pobj ends,of
R17290 T24048 T24047 prep of,ends
R17291 T24049 T24050 det the,−
R17292 T24050 T24048 pobj −,of
R17293 T24051 T24050 nummod 539,−
R17294 T24052 T24042 punct ",",location
R17295 T24053 T24054 nummod −,189
R17296 T24054 T24042 conj 189,location
R17297 T24055 T24054 cc and,189
R17298 T24056 T24054 conj −,189
R17299 T24057 T24059 nummod 87,constructs
R17300 T24058 T24059 compound reporter,constructs
R17301 T24059 T24042 appos constructs,location
R17302 T24060 T24062 auxpass is,shown
R17303 T24061 T24062 advmod also,shown
R17304 T24062 T24062 ROOT shown,shown
R17305 T24063 T24062 punct .,shown
R17306 T24064 T24086 nsubjpass Positions,indicated
R17307 T24065 T24064 prep of,Positions
R17308 T24066 T24070 nmod murine,primers
R17309 T24067 T24066 nummod SerpinB2,murine
R17310 T24068 T24070 amod proximal,primers
R17311 T24069 T24070 amod promoter-specific,primers
R17312 T24070 T24065 pobj primers,of
R17313 T24071 T24086 punct ",",indicated
R17314 T24072 T24086 nsubjpass 338,indicated
R17315 T24073 T24086 nsubjpass /,indicated
R17316 T24074 T24086 nsubjpass −,indicated
R17317 T24075 T24074 nummod 315,−
R17318 T24076 T24074 cc and,−
R17319 T24077 T24080 nummod −,+19
R17320 T24078 T24079 nummod 5,/
R17321 T24079 T24080 compound /,+19
R17322 T24080 T24074 conj +19,−
R17323 T24081 T24080 acl used,+19
R17324 T24082 T24081 prep in,used
R17325 T24083 T24084 compound ChIP,assays
R17326 T24084 T24082 pobj assays,in
R17327 T24085 T24086 auxpass are,indicated
R17328 T24086 T24086 ROOT indicated,indicated
R17329 T24087 T24086 punct .,indicated
R17330 T24088 T24091 punct (,RAW
R17331 T24089 T24091 nmod B,RAW
R17332 T24090 T24091 punct ),RAW
R17333 T24091 T24096 nsubjpass RAW,transfected
R17334 T24092 T24091 nummod 264.7,RAW
R17335 T24093 T24096 nsubjpass macrophages,transfected
R17336 T24094 T24096 auxpass were,transfected
R17337 T24095 T24096 advmod transiently,transfected
R17338 T24096 T24096 ROOT transfected,transfected
R17339 T24097 T24096 prep with,transfected
R17340 T24098 T24104 det the,constructs
R17341 T24099 T24100 amod indicated,murine
R17342 T24100 T24104 compound murine,constructs
R17343 T24101 T24103 nmod SerpinB2,reporter
R17344 T24102 T24103 amod promoter-luciferase,reporter
R17345 T24103 T24104 compound reporter,constructs
R17346 T24104 T24097 pobj constructs,with
R17347 T24105 T24096 cc and,transfected
R17348 T24106 T24107 preconj either,left
R17349 T24107 T24096 conj left,transfected
R17350 T24108 T24107 oprd untreated,left
R17351 T24109 T24108 cc or,untreated
R17352 T24110 T24108 conj treated,untreated
R17353 T24111 T24110 prep with,treated
R17354 T24112 T24114 nummod 100,LPS
R17355 T24113 T24114 compound ng/ml,LPS
R17356 T24114 T24111 pobj LPS,with
R17357 T24115 T24110 prep for,treated
R17358 T24116 T24117 nummod 16,hrs
R17359 T24117 T24115 pobj hrs,for
R17360 T24118 T24096 punct .,transfected
R17361 T24119 T24120 det The,results
R17362 T24120 T24121 nsubj results,show
R17363 T24121 T24121 ROOT show,show
R17364 T24122 T24124 amod relative,activity
R17365 T24123 T24124 compound luciferase,activity
R17366 T24124 T24121 dobj activity,show
R17367 T24125 T24124 prep following,activity
R17368 T24126 T24127 compound LPS,treatment
R17369 T24127 T24125 pobj treatment,following
R17370 T24128 T24121 cc and,show
R17371 T24129 T24121 conj represent,show
R17372 T24130 T24131 det the,mean
R17373 T24131 T24129 dobj mean,represent
R17374 T24132 T24131 cc and,mean
R17375 T24133 T24131 conj SEM,mean
R17376 T24134 T24133 prep of,SEM
R17377 T24135 T24134 pobj 4,of
R17378 T24136 T24138 nummod 7,experiments
R17379 T24137 T24138 amod independent,experiments
R17380 T24138 T24133 appos experiments,SEM
R17381 T24139 T24121 punct .,show

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T23936 1844-1855 NN denotes experiments
T23935 1832-1843 JJ denotes independent
T23934 1828-1831 CD denotes 4–7
T23933 1825-1827 IN denotes of
T23932 1821-1824 NN denotes SEM
T23931 1817-1820 CC denotes and
T23930 1812-1816 NN denotes mean
T23929 1808-1811 DT denotes the
T23928 1798-1807 VB denotes represent
T23927 1794-1797 CC denotes and
T23926 1784-1793 NN denotes treatment
T23925 1780-1783 NN denotes LPS
T23924 1770-1779 VB denotes following
T23923 1761-1769 NN denotes activity
T23922 1750-1760 NN denotes luciferase
T23921 1741-1749 JJ denotes relative
T23920 1736-1740 VB denotes show
T23919 1728-1735 NN denotes results
T23918 1724-1727 DT denotes The
T23917 1719-1722 NN denotes hrs
T23916 1716-1718 CD denotes 16
T23915 1712-1715 IN denotes for
T23914 1708-1711 NN denotes LPS
T23913 1702-1707 NN denotes ng/ml
T23912 1698-1701 CD denotes 100
T23911 1693-1697 IN denotes with
T23910 1685-1692 VB denotes treated
T23909 1682-1684 CC denotes or
T23908 1672-1681 JJ denotes untreated
T23907 1667-1671 JJ denotes left
T23906 1660-1666 CC denotes either
T23905 1656-1659 CC denotes and
T23904 1645-1655 NN denotes constructs
T23903 1636-1644 NN denotes reporter
T23902 1616-1635 NN denotes promoter-luciferase
T23901 1607-1615 NN denotes SerpinB2
T23885 1504-1510 NN denotes assays
T23884 1499-1503 NN denotes ChIP
T23883 1496-1498 IN denotes in
T23882 1491-1495 VB denotes used
T23881 1484-1490 CD denotes −5/+19
T23880 1480-1483 CC denotes and
T23879 1471-1479 CD denotes 338/−315
T23878 1469-1470 -COMMA- denotes ,
T23877 1462-1469 NN denotes primers
T23876 1444-1461 JJ denotes promoter-specific
T23875 1435-1443 JJ denotes proximal
T23874 1426-1434 NN denotes SerpinB2
T23873 1419-1425 JJ denotes murine
T23872 1416-1418 IN denotes of
T23871 1406-1415 NN denotes Positions
T23870 1399-1404 VB denotes shown
T23869 1394-1398 RB denotes also
T23868 1391-1393 VB denotes is
T23867 1380-1390 NN denotes constructs
T23866 1371-1379 NN denotes reporter
T23865 1367-1370 CD denotes −87
T23864 1363-1366 CC denotes and
T23863 1358-1362 CD denotes −189
T23862 1356-1357 -COMMA- denotes ,
T23861 1352-1356 CD denotes −539
T23860 1348-1351 DT denotes the
T23859 1345-1347 IN denotes of
T23858 1340-1344 NN denotes ends
T23857 1337-1339 CD denotes 5′
T23856 1333-1336 DT denotes the
T23855 1330-1332 IN denotes of
T23854 1321-1329 NN denotes location
T23853 1317-1320 DT denotes The
T23852 1310-1315 NN denotes boxes
T23851 1305-1309 IN denotes with
T23850 1295-1304 VB denotes indicated
T23849 1286-1294 NN denotes elements
T23848 1275-1285 JJ denotes regulatory
T23847 1264-1274 JJ denotes cis-acting
T23846 1254-1263 NN denotes candidate
T23845 1251-1253 IN denotes of
T23844 1242-1250 NN denotes location
T23843 1238-1241 DT denotes the
T23842 1233-1237 IN denotes with
T23841 1224-1232 NN denotes promoter
T23840 1215-1223 NN denotes SerpinB2
T23839 1208-1214 JJ denotes murine
T23838 1204-1207 DT denotes the
T23837 1201-1203 IN denotes of
T23836 1194-1200 NN denotes region
T23835 1185-1193 NN denotes −539/+92
T23834 1181-1184 DT denotes the
T23833 1178-1180 IN denotes of
T23832 1163-1177 NN denotes representation
T23831 1153-1162 JJ denotes Schematic
T23830 1151-1152 -RRB- denotes )
T23829 1150-1151 NN denotes A
T23828 1149-1150 -LRB- denotes (
T23827 1139-1147 NN denotes promoter
T23826 1130-1138 NN denotes SerpinB2
T23825 1123-1129 JJ denotes murine
T23824 1119-1122 DT denotes the
T23823 1116-1118 IN denotes of
T23822 1097-1115 NN denotes LPS-responsiveness
T23821 1093-1096 DT denotes the
T23820 1089-1092 IN denotes for
T23819 1080-1088 VB denotes required
T23818 1071-1079 NN denotes elements
T23817 1060-1070 JJ denotes cis-acting
T23816 1057-1059 IN denotes of
T23815 1042-1056 NN denotes Identification
T23900 1600-1606 JJ denotes murine
T23899 1590-1599 VB denotes indicated
T23898 1586-1589 DT denotes the
T23897 1581-1585 IN denotes with
T23896 1569-1580 VB denotes transfected
T23895 1557-1568 RB denotes transiently
T23894 1552-1556 VB denotes were
T23893 1540-1551 NN denotes macrophages
T23892 1534-1539 CD denotes 264.7
T23891 1530-1533 NN denotes RAW
T23890 1528-1529 -RRB- denotes )
T23889 1527-1528 NN denotes B
T23888 1526-1527 -LRB- denotes (
T23887 1515-1525 VB denotes indicated.
T23886 1511-1514 VB denotes are
T11843 2599-2607 NN denotes promoter
T11842 2590-2598 JJ denotes proximal
T11841 2581-2589 NN denotes SerpinB2
T11840 2577-2580 DT denotes the
T11839 2572-2576 IN denotes from
T11838 2558-2571 NN denotes transcription
T11837 2544-2557 JJ denotes LPS-inducible
T11836 2540-2543 IN denotes for
T11835 2531-2539 JJ denotes critical
T11834 2527-2530 VB denotes are
T11833 2518-2526 NN denotes elements
T11832 2507-2517 JJ denotes cis-acting
T11831 2502-2506 NN denotes AP-1
T11830 2497-2501 DT denotes both
T11829 2493-2496 CC denotes and
T11828 2489-2492 NN denotes CRE
T11827 2485-2488 DT denotes the
T11826 2482-2484 IN denotes as
T11825 2477-2481 RB denotes well
T11824 2474-2476 RB denotes as
T11823 2472-2473 -COMMA- denotes ,
T11822 2465-2472 NN denotes element
T11821 2459-2464 NN denotes C/EBP
T11820 2455-2458 DT denotes the
T11819 2450-2454 IN denotes that
T11818 2445-2449 VB denotes show
T11817 2440-2444 NN denotes data
T11816 2434-2439 DT denotes These
T11815 2424-2432 NN denotes promoter
T11814 2415-2423 NN denotes SerpinB2
T11813 2408-2414 JJ denotes murine
T11812 2404-2407 DT denotes the
T11811 2399-2403 IN denotes from
T11810 2390-2398 NN denotes activity
T11809 2379-2389 NN denotes luciferase
T11808 2365-2378 JJ denotes LPS-inducible
T11807 2357-2364 VB denotes reduced
T11806 2343-2356 RB denotes significantly
T11805 2340-2342 CC denotes or
T11804 2329-2339 RB denotes completely
T11803 2327-2328 -COMMA- denotes ,
T11802 2320-2327 CD denotes −94/−88
T11801 2316-2319 CC denotes and
T11800 2306-2315 CD denotes −106/−100
T11799 2303-2305 IN denotes at
T11798 2297-2302 NN denotes sites
T11797 2292-2296 NN denotes AP-1
T11796 2288-2291 CD denotes two
T11795 2284-2287 DT denotes the
T11794 2281-2283 IN denotes of
T11793 2274-2280 DT denotes either
T11792 2271-2273 CC denotes or
T11791 2261-2270 CD denotes −177/−172
T11790 2258-2260 IN denotes at
T11789 2254-2257 NN denotes CRE
T11788 2250-2253 DT denotes the
T11787 2247-2249 IN denotes of
T11786 2238-2246 NN denotes mutation
T11785 2236-2237 -COMMA- denotes ,
T11784 2234-2236 NN denotes 4B
T11783 2229-2233 NNP denotes Fig.
T11782 2226-2228 IN denotes in
T11781 2220-2225 VB denotes shown
T11780 2217-2219 IN denotes As
T11779 2207-2215 NN denotes promoter
T11778 2198-2206 NN denotes SerpinB2
T11777 2191-2197 JJ denotes murine
T11776 2187-2190 DT denotes the
T11775 2184-2186 IN denotes of
T11774 2175-2183 NN denotes response
T11773 2171-2174 NN denotes LPS
T11772 2167-2170 DT denotes the
T11771 2164-2166 IN denotes in
T11770 2159-2163 NN denotes role
T11769 2157-2158 DT denotes a
T11768 2150-2156 VB denotes played
T11767 2145-2149 PRP denotes they
T11766 2137-2144 IN denotes whether
T11765 2125-2136 VB denotes investigate
T11764 2122-2124 TO denotes to
T11763 2109-2121 NN denotes substitution
T11762 2098-2108 NN denotes nucleotide
T11761 2095-2097 IN denotes by
T11760 2087-2094 VB denotes mutated
T11759 2082-2086 RB denotes also
T11758 2077-2081 VB denotes were
T11757 2071-2076 NN denotes sites
T11756 2065-2070 DT denotes these
T11755 2063-2064 -COMMA- denotes ,
T11754 2062-2063 -RRB- denotes ]
T11753 2060-2062 CD denotes 37
T11752 2059-2060 -LRB- denotes [
T11751 2050-2058 NN denotes promoter
T11750 2041-2049 NN denotes SERPINB2
T11749 2035-2040 JJ denotes human
T11748 2031-2034 DT denotes the
T11747 2028-2030 IN denotes of
T11746 2009-2027 NN denotes PMA-responsiveness
T11745 2005-2008 DT denotes the
T11744 2002-2004 IN denotes in
T11743 1990-2001 NN denotes involvement
T11742 1977-1989 VB denotes demonstrated
T11741 1971-1976 PRP-DOLLAR- denotes their
T11740 1967-1970 CC denotes and
T11739 1958-1966 NN denotes promoter
T11738 1949-1957 NN denotes SerpinB2
T11737 1942-1948 JJ denotes murine
T11736 1938-1941 DT denotes the
T11735 1935-1937 IN denotes in
T11734 1929-1934 NN denotes sites
T11733 1924-1928 NN denotes AP-1
T11732 1920-1923 CD denotes two
T11731 1916-1919 CC denotes and
T11730 1912-1915 NN denotes CRE
T11729 1908-1911 DT denotes the
T11728 1905-1907 IN denotes of
T11727 1896-1904 NN denotes position
T11726 1892-1895 CC denotes and
T11725 1883-1891 NN denotes sequence
T11724 1873-1882 VB denotes conserved
T11723 1869-1872 DT denotes the
T11722 1857-1868 VB denotes Considering
T11721 995-996 -RRB- denotes ]
T11720 993-995 CD denotes 58
T11719 992-993 -LRB- denotes [
T11718 987-991 NN denotes gene
T11717 978-986 NN denotes SerpinB2
T11716 974-977 DT denotes the
T11715 971-973 IN denotes of
T11714 960-970 NN denotes activation
T11713 948-959 JJ denotes LPS-induced
T11712 945-947 IN denotes in
T11711 940-944 NN denotes site
T11710 934-939 NN denotes C/EBP
T11709 929-933 DT denotes this
T11708 918-928 VB denotes implicated
T11707 909-917 RB denotes recently
T11706 904-908 RB denotes also
T11705 899-903 VB denotes have
T11704 892-898 NN denotes Others
T11703 881-890 NN denotes construct
T11702 872-880 NN denotes deletion
T11701 863-871 NN denotes promoter
T11700 854-862 NN denotes SerpinB2
T11699 849-853 CD denotes −189
T11698 845-848 DT denotes the
T11697 841-844 IN denotes for
T11696 832-840 VB denotes observed
T11695 825-831 NN denotes levels
T11694 821-824 DT denotes the
T11693 818-820 TO denotes to
T11692 810-817 JJ denotes similar
T11691 808-809 -COMMA- denotes ,
T11690 800-808 NN denotes activity
T11689 791-799 NN denotes promoter
T11688 780-790 VB denotes eliminated
T11687 769-779 RB denotes completely
T11686 767-768 -RRB- denotes )
T11685 758-767 NN denotes −203/−192
T11684 757-758 -LRB- denotes (
T11683 752-756 NN denotes site
T11682 746-751 NN denotes C/EBP
T11681 742-745 DT denotes the
T11680 739-741 IN denotes of
T11679 730-738 NN denotes mutation
T11678 728-729 -COMMA- denotes ,
T11677 720-728 NN denotes contrast
T11676 717-719 IN denotes In
T11675 707-715 NN denotes activity
T11674 698-706 NN denotes promoter
T11673 686-697 JJ denotes LPS-induced
T11672 677-685 VB denotes decrease
T11671 673-676 RB denotes not
T11670 669-672 VB denotes did
T11669 664-668 NN denotes site
T11668 662-663 -RRB- denotes )
T11667 653-662 CD denotes −296/−288
T11666 652-653 -LRB- denotes (
T11665 646-651 NN denotes Oct-1
T11664 638-645 JJ denotes variant
T11663 634-637 DT denotes the
T11662 631-633 CC denotes or
T11661 629-630 -COMMA- denotes ,
T11660 628-629 -RRB- denotes )
T11659 619-628 CD denotes −412/−407
T11658 618-619 -LRB- denotes (
T11657 613-617 NN denotes PU.1
T11656 611-612 -COMMA- denotes ,
T11655 610-611 -RRB- denotes )
T11654 601-610 CD denotes −538/−533
T11653 600-601 -LRB- denotes (
T11652 596-599 NN denotes box
T11651 594-595 NN denotes E
T11650 584-593 NN denotes consensus
T11649 580-583 DT denotes the
T11648 577-579 IN denotes of
T11647 568-576 NN denotes mutation
T11646 566-567 -COMMA- denotes ,
T11645 564-566 NN denotes 4B
T11644 559-563 NNP denotes Fig.
T11643 556-558 IN denotes in
T11642 550-555 VB denotes shown
T11641 547-549 IN denotes As
T11640 544-545 -RRB- denotes )
T11639 542-544 NN denotes 4A
T11638 537-541 NN denotes Fig.
T11637 536-537 -LRB- denotes (
T11636 526-535 NN denotes construct
T11635 521-525 NN denotes gene
T11634 512-520 NN denotes reporter
T11633 492-511 NN denotes promoter-luciferase
T11632 483-491 NN denotes SerpinB2
T11631 476-482 JJ denotes murine
T11630 466-475 NN denotes pGLmP-539
T11629 462-465 DT denotes the
T11628 459-461 TO denotes to
T11627 451-458 VB denotes binding
T11626 444-450 NN denotes factor
T11625 430-443 NN denotes transcription
T11624 422-429 VB denotes disrupt
T11623 419-421 TO denotes to
T11622 410-418 VB denotes designed
T11621 397-409 NN denotes substitution
T11620 386-396 NN denotes nucleotide
T11619 383-385 IN denotes by
T11618 374-382 VB denotes targeted
T11617 369-373 VB denotes were
T11616 367-368 -RRB- denotes ]
T11615 365-367 CD denotes 57
T11614 364-365 -LRB- denotes [
T11613 358-363 NN denotes genes
T11612 352-357 JJ denotes other
T11611 349-351 IN denotes in
T11610 335-348 NN denotes transcription
T11609 321-334 JJ denotes LPS-inducible
T11608 313-320 VB denotes mediate
T11607 310-312 TO denotes to
T11606 301-309 VB denotes reported
T11605 290-300 RB denotes previously
T11604 282-289 NN denotes factors
T11603 268-281 NN denotes transcription
T11602 264-267 IN denotes for
T11601 258-263 NN denotes sites
T11600 250-257 NN denotes binding
T11599 240-249 NN denotes candidate
T11598 232-239 JJ denotes several
T11597 230-231 -COMMA- denotes ,
T11596 217-230 NN denotes transcription
T11595 203-216 JJ denotes LPS-inducible
T11594 199-202 IN denotes for
T11593 189-198 JJ denotes essential
T11592 184-188 CD denotes −189
T11591 180-183 CC denotes and
T11590 175-179 CD denotes −539
T11589 167-174 IN denotes between
T11588 158-166 NN denotes elements
T11587 147-157 JJ denotes regulatory
T11586 135-146 VB denotes investigate
T11585 132-134 TO denotes To
T11584 118-131 NN denotes Transcription
T11583 104-117 JJ denotes LPS-inducible
T11582 96-103 JJ denotes Optimal
T11581 92-95 IN denotes for
T11580 82-91 JJ denotes Essential
T11579 78-81 VB denotes are
T11578 69-77 NNP denotes Promoter
T11577 60-68 NNP denotes Proximal
T11576 55-59 NNP denotes Gene
T11575 46-54 NNP denotes SerpinB2
T11574 39-45 NNP denotes Murine
T11573 35-38 DT denotes the
T11572 32-34 IN denotes in
T11571 26-31 NN denotes Sites
T11570 21-25 NN denotes AP-1
T11569 17-20 CD denotes Two
T11568 13-16 CC denotes and
T11567 9-12 NN denotes CRE
T11566 7-8 -COMMA- denotes ,
T11565 2-7 NN denotes C/EBP
T11564 0-1 DT denotes A
R8509 T11565 T11566 arg1Of C/EBP,","
R8510 T11566 T11568 arg1Of ",",and
R8511 T11567 T11566 arg2Of CRE,","
R8512 T11569 T11568 arg2Of Two,and
R8513 T11571 T11564 arg1Of Sites,A
R8514 T11571 T11565 arg1Of Sites,C/EBP
R8515 T11571 T11567 arg1Of Sites,CRE
R8516 T11571 T11569 arg1Of Sites,Two
R8517 T11571 T11570 arg1Of Sites,AP-1
R8518 T11571 T11572 arg1Of Sites,in
R8519 T11571 T11579 arg1Of Sites,are
R8520 T11571 T11580 arg1Of Sites,Essential
R8521 T11578 T11572 arg2Of Promoter,in
R8522 T11578 T11573 arg1Of Promoter,the
R8523 T11578 T11574 arg1Of Promoter,Murine
R8524 T11578 T11575 arg1Of Promoter,SerpinB2
R8525 T11578 T11576 arg1Of Promoter,Gene
R8526 T11578 T11577 arg1Of Promoter,Proximal
R8527 T11580 T11579 arg2Of Essential,are
R8528 T11580 T11581 arg1Of Essential,for
R8529 T11584 T11581 arg2Of Transcription,for
R8530 T11584 T11582 arg1Of Transcription,Optimal
R8531 T11584 T11583 arg1Of Transcription,LPS-inducible
R8532 T11586 T11585 arg1Of investigate,To
R8533 T11588 T11586 arg2Of elements,investigate
R8534 T11588 T11587 arg1Of elements,regulatory
R8535 T11588 T11589 arg1Of elements,between
R8536 T11590 T11591 arg1Of −539,and
R8537 T11591 T11589 arg2Of and,between
R8538 T11591 T11593 arg1Of and,essential
R8539 T11592 T11591 arg2Of −189,and
R8540 T11593 T11594 arg1Of essential,for
R8541 T11596 T11594 arg2Of transcription,for
R8542 T11596 T11595 arg1Of transcription,LPS-inducible
R8543 T11601 T11598 arg1Of sites,several
R8544 T11601 T11599 arg1Of sites,candidate
R8545 T11601 T11600 arg1Of sites,binding
R8546 T11601 T11602 arg1Of sites,for
R8547 T11601 T11617 arg1Of sites,were
R8548 T11601 T11618 arg2Of sites,targeted
R8549 T11604 T11602 arg2Of factors,for
R8550 T11604 T11603 arg1Of factors,transcription
R8551 T11604 T11606 arg2Of factors,reported
R8552 T11604 T11608 arg1Of factors,mediate
R8553 T11606 T11605 arg1Of reported,previously
R8554 T11608 T11606 arg3Of mediate,reported
R8555 T11608 T11607 arg1Of mediate,to
R8556 T11608 T11614 arg1Of mediate,[
R8557 T11610 T11608 arg2Of transcription,mediate
R8558 T11610 T11609 arg1Of transcription,LPS-inducible
R8559 T11610 T11611 arg1Of transcription,in
R8560 T11613 T11611 arg2Of genes,in
R8561 T11613 T11612 arg1Of genes,other
R8562 T11615 T11614 arg2Of 57,[
R8563 T11616 T11614 arg3Of ],[
R8564 T11618 T11585 modOf targeted,To
R8565 T11618 T11597 arg1Of targeted,","
R8566 T11618 T11617 arg2Of targeted,were
R8567 T11621 T11618 arg1Of substitution,targeted
R8568 T11621 T11619 arg2Of substitution,by
R8569 T11621 T11620 arg1Of substitution,nucleotide
R8570 T11621 T11622 arg2Of substitution,designed
R8571 T11622 T11623 modOf designed,to
R8572 T11624 T11623 arg1Of disrupt,to
R8573 T11626 T11624 arg2Of factor,disrupt
R8574 T11626 T11625 arg1Of factor,transcription
R8575 T11626 T11627 arg1Of factor,binding
R8576 T11627 T11628 arg1Of binding,to
R8577 T11636 T11628 arg2Of construct,to
R8578 T11636 T11629 arg1Of construct,the
R8579 T11636 T11630 arg1Of construct,pGLmP-539
R8580 T11636 T11631 arg1Of construct,murine
R8581 T11636 T11632 arg1Of construct,SerpinB2
R8582 T11636 T11633 arg1Of construct,promoter-luciferase
R8583 T11636 T11634 arg1Of construct,reporter
R8584 T11636 T11635 arg1Of construct,gene
R8585 T11636 T11637 arg1Of construct,(
R8586 T11639 T11637 arg2Of 4A,(
R8587 T11639 T11638 arg1Of 4A,Fig.
R8588 T11640 T11637 arg3Of ),(
R8589 T11642 T11641 arg2Of shown,As
R8590 T11642 T11643 arg1Of shown,in
R8591 T11645 T11643 arg2Of 4B,in
R8592 T11645 T11644 arg1Of 4B,Fig.
R8593 T11647 T11648 arg1Of mutation,of
R8594 T11647 T11656 arg1Of mutation,","
R8595 T11652 T11648 arg2Of box,of
R8596 T11652 T11649 arg1Of box,the
R8597 T11652 T11650 arg1Of box,consensus
R8598 T11652 T11651 arg1Of box,E
R8599 T11652 T11653 arg1Of box,(
R8600 T11654 T11653 arg2Of −538/−533,(
R8601 T11655 T11653 arg3Of ),(
R8602 T11656 T11662 arg1Of ",",or
R8603 T11657 T11656 arg2Of PU.1,","
R8604 T11657 T11658 arg1Of PU.1,(
R8605 T11659 T11658 arg2Of −412/−407,(
R8606 T11660 T11658 arg3Of ),(
R8607 T11662 T11661 arg1Of or,","
R8608 T11662 T11670 arg1Of or,did
R8609 T11662 T11672 arg1Of or,decrease
R8610 T11665 T11663 arg1Of Oct-1,the
R8611 T11665 T11664 arg1Of Oct-1,variant
R8612 T11665 T11666 arg1Of Oct-1,(
R8613 T11667 T11666 arg2Of −296/−288,(
R8614 T11668 T11666 arg3Of ),(
R8615 T11669 T11662 arg2Of site,or
R8616 T11669 T11665 arg1Of site,Oct-1
R8617 T11672 T11641 arg1Of decrease,As
R8618 T11672 T11646 arg1Of decrease,","
R8619 T11672 T11670 arg2Of decrease,did
R8620 T11672 T11671 arg1Of decrease,not
R8621 T11675 T11672 arg2Of activity,decrease
R8622 T11675 T11673 arg1Of activity,LPS-induced
R8623 T11675 T11674 arg1Of activity,promoter
R8624 T11677 T11676 arg2Of contrast,In
R8625 T11679 T11680 arg1Of mutation,of
R8626 T11679 T11688 arg1Of mutation,eliminated
R8627 T11683 T11680 arg2Of site,of
R8628 T11683 T11681 arg1Of site,the
R8629 T11683 T11682 arg1Of site,C/EBP
R8630 T11683 T11684 arg1Of site,(
R8631 T11685 T11684 arg2Of −203/−192,(
R8632 T11686 T11684 arg3Of ),(
R8633 T11688 T11676 arg1Of eliminated,In
R8634 T11688 T11678 arg1Of eliminated,","
R8635 T11688 T11687 arg1Of eliminated,completely
R8636 T11690 T11688 arg2Of activity,eliminated
R8637 T11690 T11689 arg1Of activity,promoter
R8638 T11690 T11691 arg1Of activity,","
R8639 T11690 T11692 arg1Of activity,similar
R8640 T11692 T11693 arg1Of similar,to
R8641 T11695 T11693 arg2Of levels,to
R8642 T11695 T11694 arg1Of levels,the
R8643 T11695 T11696 arg2Of levels,observed
R8644 T11696 T11697 arg1Of observed,for
R8645 T11703 T11697 arg2Of construct,for
R8646 T11703 T11698 arg1Of construct,the
R8647 T11703 T11699 arg1Of construct,−189
R8648 T11703 T11700 arg1Of construct,SerpinB2
R8649 T11703 T11701 arg1Of construct,promoter
R8650 T11703 T11702 arg1Of construct,deletion
R8651 T11704 T11705 arg1Of Others,have
R8652 T11704 T11708 arg1Of Others,implicated
R8653 T11708 T11705 arg2Of implicated,have
R8654 T11708 T11706 arg1Of implicated,also
R8655 T11708 T11707 arg1Of implicated,recently
R8656 T11708 T11719 arg1Of implicated,[
R8657 T11711 T11708 arg2Of site,implicated
R8658 T11711 T11709 arg1Of site,this
R8659 T11711 T11710 arg1Of site,C/EBP
R8660 T11711 T11712 arg1Of site,in
R8661 T11714 T11712 arg2Of activation,in
R8662 T11714 T11713 arg1Of activation,LPS-induced
R8663 T11714 T11715 arg1Of activation,of
R8664 T11718 T11715 arg2Of gene,of
R8665 T11718 T11716 arg1Of gene,the
R8666 T11718 T11717 arg1Of gene,SerpinB2
R8667 T11720 T11719 arg2Of 58,[
R8668 T11721 T11719 arg3Of ],[
R8669 T11725 T11726 arg1Of sequence,and
R8670 T11726 T11722 arg2Of and,Considering
R8671 T11726 T11723 arg1Of and,the
R8672 T11726 T11724 arg2Of and,conserved
R8673 T11726 T11728 arg1Of and,of
R8674 T11726 T11744 arg1Of and,in
R8675 T11727 T11726 arg2Of position,and
R8676 T11730 T11731 arg1Of CRE,and
R8677 T11732 T11731 arg2Of two,and
R8678 T11734 T11728 arg2Of sites,of
R8679 T11734 T11729 arg1Of sites,the
R8680 T11734 T11730 arg1Of sites,CRE
R8681 T11734 T11732 arg1Of sites,two
R8682 T11734 T11733 arg1Of sites,AP-1
R8683 T11734 T11735 arg1Of sites,in
R8684 T11739 T11736 arg1Of promoter,the
R8685 T11739 T11737 arg1Of promoter,murine
R8686 T11739 T11738 arg1Of promoter,SerpinB2
R8687 T11739 T11740 arg1Of promoter,and
R8688 T11740 T11735 arg2Of and,in
R8689 T11743 T11740 arg2Of involvement,and
R8690 T11743 T11741 arg1Of involvement,their
R8691 T11743 T11742 arg2Of involvement,demonstrated
R8692 T11746 T11744 arg2Of PMA-responsiveness,in
R8693 T11746 T11745 arg1Of PMA-responsiveness,the
R8694 T11746 T11747 arg1Of PMA-responsiveness,of
R8695 T11751 T11747 arg2Of promoter,of
R8696 T11751 T11748 arg1Of promoter,the
R8697 T11751 T11749 arg1Of promoter,human
R8698 T11751 T11750 arg1Of promoter,SERPINB2
R8699 T11751 T11752 arg1Of promoter,[
R8700 T11753 T11752 arg2Of 37,[
R8701 T11754 T11752 arg3Of ],[
R8702 T11757 T11756 arg1Of sites,these
R8703 T11757 T11758 arg1Of sites,were
R8704 T11757 T11760 arg2Of sites,mutated
R8705 T11757 T11765 arg1Of sites,investigate
R8706 T11760 T11722 modOf mutated,Considering
R8707 T11760 T11755 arg1Of mutated,","
R8708 T11760 T11758 arg2Of mutated,were
R8709 T11760 T11759 arg1Of mutated,also
R8710 T11760 T11764 modOf mutated,to
R8711 T11763 T11760 arg1Of substitution,mutated
R8712 T11763 T11761 arg2Of substitution,by
R8713 T11763 T11762 arg1Of substitution,nucleotide
R8714 T11765 T11764 arg1Of investigate,to
R8715 T11767 T11768 arg1Of they,played
R8716 T11768 T11765 arg2Of played,investigate
R8717 T11768 T11766 arg1Of played,whether
R8718 T11768 T11771 arg1Of played,in
R8719 T11770 T11768 arg2Of role,played
R8720 T11770 T11769 arg1Of role,a
R8721 T11774 T11771 arg2Of response,in
R8722 T11774 T11772 arg1Of response,the
R8723 T11774 T11773 arg1Of response,LPS
R8724 T11774 T11775 arg1Of response,of
R8725 T11779 T11775 arg2Of promoter,of
R8726 T11779 T11776 arg1Of promoter,the
R8727 T11779 T11777 arg1Of promoter,murine
R8728 T11779 T11778 arg1Of promoter,SerpinB2
R8729 T11781 T11780 arg2Of shown,As
R8730 T11781 T11782 arg1Of shown,in
R8731 T11784 T11782 arg2Of 4B,in
R8732 T11784 T11783 arg1Of 4B,Fig.
R8733 T11786 T11787 arg1Of mutation,of
R8734 T11786 T11790 arg1Of mutation,at
R8735 T11786 T11803 arg1Of mutation,","
R8736 T11786 T11807 arg1Of mutation,reduced
R8737 T11789 T11787 arg2Of CRE,of
R8738 T11789 T11788 arg1Of CRE,the
R8739 T11793 T11790 arg2Of either,at
R8740 T11793 T11791 arg1Of either,−177/−172
R8741 T11793 T11792 arg1Of either,or
R8742 T11793 T11794 arg1Of either,of
R8743 T11798 T11794 arg2Of sites,of
R8744 T11798 T11795 arg1Of sites,the
R8745 T11798 T11796 arg1Of sites,two
R8746 T11798 T11797 arg1Of sites,AP-1
R8747 T11798 T11799 arg1Of sites,at
R8748 T11800 T11801 arg1Of −106/−100,and
R8749 T11801 T11799 arg2Of and,at
R8750 T11802 T11801 arg2Of −94/−88,and
R8751 T11804 T11805 arg1Of completely,or
R8752 T11806 T11805 arg2Of significantly,or
R8753 T11807 T11780 arg1Of reduced,As
R8754 T11807 T11785 arg1Of reduced,","
R8755 T11807 T11804 arg1Of reduced,completely
R8756 T11807 T11806 arg1Of reduced,significantly
R8757 T11810 T11807 arg2Of activity,reduced
R8758 T11810 T11808 arg1Of activity,LPS-inducible
R8759 T11810 T11809 arg1Of activity,luciferase
R8760 T11810 T11811 arg1Of activity,from
R8761 T11815 T11811 arg2Of promoter,from
R8762 T11815 T11812 arg1Of promoter,the
R8763 T11815 T11813 arg1Of promoter,murine
R8764 T11815 T11814 arg1Of promoter,SerpinB2
R8765 T11817 T11816 arg1Of data,These
R8766 T11817 T11818 arg1Of data,show
R8767 T11822 T11820 arg1Of element,the
R8768 T11822 T11821 arg1Of element,C/EBP
R8769 T11822 T11826 arg1Of element,as
R8770 T11826 T11823 arg1Of as,","
R8771 T11826 T11824 arg1Of as,as
R8772 T11826 T11825 arg1Of as,well
R8773 T11826 T11829 arg1Of as,and
R8774 T11828 T11826 arg2Of CRE,as
R8775 T11828 T11827 arg1Of CRE,the
R8776 T11829 T11834 arg1Of and,are
R8777 T11829 T11835 arg1Of and,critical
R8778 T11833 T11829 arg2Of elements,and
R8779 T11833 T11830 arg1Of elements,both
R8780 T11833 T11831 arg1Of elements,AP-1
R8781 T11833 T11832 arg1Of elements,cis-acting
R8782 T11834 T11818 arg2Of are,show
R8783 T11834 T11819 arg1Of are,that
R8784 T11835 T11834 arg2Of critical,are
R8785 T11835 T11836 arg1Of critical,for
R8786 T11838 T11836 arg2Of transcription,for
R8787 T11838 T11837 arg1Of transcription,LPS-inducible
R8788 T11838 T11839 arg1Of transcription,from
R8789 T11843 T11839 arg2Of promoter,from
R8790 T11843 T11840 arg1Of promoter,the
R8791 T11843 T11841 arg1Of promoter,SerpinB2
R8792 T11843 T11842 arg1Of promoter,proximal
R17112 T23815 T23816 arg1Of Identification,of
R17113 T23818 T23816 arg2Of elements,of
R17114 T23818 T23817 arg1Of elements,cis-acting
R17115 T23818 T23819 arg2Of elements,required
R17116 T23819 T23820 arg1Of required,for
R17117 T23822 T23820 arg2Of LPS-responsiveness,for
R17118 T23822 T23821 arg1Of LPS-responsiveness,the
R17119 T23822 T23823 arg1Of LPS-responsiveness,of
R17120 T23827 T23823 arg2Of promoter,of
R17121 T23827 T23824 arg1Of promoter,the
R17122 T23827 T23825 arg1Of promoter,murine
R17123 T23827 T23826 arg1Of promoter,SerpinB2
R17124 T23829 T23828 arg2Of A,(
R17125 T23830 T23828 arg3Of ),(
R17126 T23832 T23828 arg1Of representation,(
R17127 T23832 T23831 arg1Of representation,Schematic
R17128 T23832 T23833 arg1Of representation,of
R17129 T23832 T23842 arg1Of representation,with
R17130 T23836 T23833 arg2Of region,of
R17131 T23836 T23834 arg1Of region,the
R17132 T23836 T23835 arg1Of region,−539/+92
R17133 T23836 T23837 arg1Of region,of
R17134 T23841 T23837 arg2Of promoter,of
R17135 T23841 T23838 arg1Of promoter,the
R17136 T23841 T23839 arg1Of promoter,murine
R17137 T23841 T23840 arg1Of promoter,SerpinB2
R17138 T23844 T23842 arg2Of location,with
R17139 T23844 T23843 arg1Of location,the
R17140 T23844 T23845 arg1Of location,of
R17141 T23849 T23845 arg2Of elements,of
R17142 T23849 T23846 arg1Of elements,candidate
R17143 T23849 T23847 arg1Of elements,cis-acting
R17144 T23849 T23848 arg1Of elements,regulatory
R17145 T23849 T23850 arg2Of elements,indicated
R17146 T23850 T23851 arg1Of indicated,with
R17147 T23852 T23851 arg2Of boxes,with
R17148 T23854 T23853 arg1Of location,The
R17149 T23854 T23855 arg1Of location,of
R17150 T23854 T23868 arg1Of location,is
R17151 T23854 T23870 arg2Of location,shown
R17152 T23858 T23855 arg2Of ends,of
R17153 T23858 T23856 arg1Of ends,the
R17154 T23858 T23857 arg1Of ends,5′
R17155 T23858 T23859 arg1Of ends,of
R17156 T23863 T23864 arg1Of −189,and
R17157 T23865 T23864 arg2Of −87,and
R17158 T23867 T23859 arg2Of constructs,of
R17159 T23867 T23860 arg1Of constructs,the
R17160 T23867 T23861 arg1Of constructs,−539
R17161 T23867 T23862 arg1Of constructs,","
R17162 T23867 T23863 arg1Of constructs,−189
R17163 T23867 T23865 arg1Of constructs,−87
R17164 T23867 T23866 arg1Of constructs,reporter
R17165 T23870 T23868 arg2Of shown,is
R17166 T23870 T23869 arg1Of shown,also
R17167 T23871 T23872 arg1Of Positions,of
R17168 T23871 T23886 arg1Of Positions,are
R17169 T23871 T23887 arg2Of Positions,indicated.
R17170 T23877 T23872 arg2Of primers,of
R17171 T23877 T23873 arg1Of primers,murine
R17172 T23877 T23874 arg1Of primers,SerpinB2
R17173 T23877 T23875 arg1Of primers,proximal
R17174 T23877 T23876 arg1Of primers,promoter-specific
R17175 T23877 T23878 arg1Of primers,","
R17176 T23879 T23880 arg1Of 338/−315,and
R17177 T23880 T23878 arg2Of and,","
R17178 T23880 T23882 arg2Of and,used
R17179 T23881 T23880 arg2Of −5/+19,and
R17180 T23882 T23883 arg1Of used,in
R17181 T23885 T23883 arg2Of assays,in
R17182 T23885 T23884 arg1Of assays,ChIP
R17183 T23887 T23886 arg2Of indicated.,are
R17184 T23889 T23888 arg2Of B,(
R17185 T23890 T23888 arg3Of ),(
R17186 T23893 T23888 arg1Of macrophages,(
R17187 T23893 T23891 arg1Of macrophages,RAW
R17188 T23893 T23892 arg1Of macrophages,264.7
R17189 T23893 T23894 arg1Of macrophages,were
R17190 T23893 T23896 arg2Of macrophages,transfected
R17191 T23896 T23886 modOf transfected,are
R17192 T23896 T23894 arg2Of transfected,were
R17193 T23896 T23895 arg1Of transfected,transiently
R17194 T23896 T23897 arg1Of transfected,with
R17195 T23904 T23898 arg1Of constructs,the
R17196 T23904 T23899 arg2Of constructs,indicated
R17197 T23904 T23900 arg1Of constructs,murine
R17198 T23904 T23901 arg1Of constructs,SerpinB2
R17199 T23904 T23902 arg1Of constructs,promoter-luciferase
R17200 T23904 T23903 arg1Of constructs,reporter
R17201 T23904 T23905 arg1Of constructs,and
R17202 T23905 T23897 arg2Of and,with
R17203 T23908 T23906 arg1Of untreated,either
R17204 T23908 T23907 arg1Of untreated,left
R17205 T23908 T23909 arg1Of untreated,or
R17206 T23910 T23909 arg2Of treated,or
R17207 T23910 T23911 arg1Of treated,with
R17208 T23912 T23913 arg1Of 100,ng/ml
R17209 T23914 T23911 arg2Of LPS,with
R17210 T23914 T23912 arg1Of LPS,100
R17211 T23917 T23905 arg2Of hrs,and
R17212 T23917 T23908 arg1Of hrs,untreated
R17213 T23917 T23910 arg2Of hrs,treated
R17214 T23917 T23915 arg1Of hrs,for
R17215 T23917 T23916 arg1Of hrs,16
R17216 T23919 T23918 arg1Of results,The
R17217 T23919 T23920 arg1Of results,show
R17218 T23919 T23928 arg1Of results,represent
R17219 T23920 T23924 arg1Of show,following
R17220 T23920 T23927 arg1Of show,and
R17221 T23923 T23920 arg2Of activity,show
R17222 T23923 T23921 arg1Of activity,relative
R17223 T23923 T23922 arg1Of activity,luciferase
R17224 T23926 T23924 arg2Of treatment,following
R17225 T23926 T23925 arg1Of treatment,LPS
R17226 T23928 T23927 arg2Of represent,and
R17227 T23930 T23931 arg1Of mean,and
R17228 T23931 T23928 arg2Of and,represent
R17229 T23931 T23929 arg1Of and,the
R17230 T23931 T23933 arg1Of and,of
R17231 T23932 T23931 arg2Of SEM,and
R17232 T23936 T23933 arg2Of experiments,of
R17233 T23936 T23934 arg1Of experiments,4–7
R17234 T23936 T23935 arg1Of experiments,independent

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T11520 2065-2076 Antecedent denotes these sites
T11519 2145-2149 Anaphor denotes they
T11518 1971-1976 Antecedent denotes their
T11517 2065-2076 Anaphor denotes these sites
R8507 T11517 T11518 boundBy these sites,their
R8508 T11519 T11517 boundBy they,these sites

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T23799 1750-1760 Protein denotes luciferase
T23798 1607-1644 Protein denotes SerpinB2 promoter-luciferase reporter
T23797 1426-1434 Protein denotes SerpinB2
T23796 1215-1223 Protein denotes SerpinB2
T23795 1130-1138 Protein denotes SerpinB2
T11530 2581-2589 Protein denotes SerpinB2
T11529 2415-2423 Protein denotes SerpinB2
T11528 2379-2389 Protein denotes luciferase
T11527 2198-2206 Protein denotes SerpinB2
T11526 2041-2049 Protein denotes SERPINB2
T11525 1949-1957 Protein denotes SerpinB2
T11524 978-986 Protein denotes SerpinB2
T11523 854-862 Protein denotes SerpinB2
T11522 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene
T11521 46-54 Protein denotes SerpinB2

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T23954 1750-1760 http://www.uniprot.org/uniprot/P08659 denotes luciferase
T23953 1625-1635 http://www.uniprot.org/uniprot/P08659 denotes luciferase
T23952 1607-1615 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T23951 1426-1434 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T23950 1215-1223 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T23949 1130-1138 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T11888 613-617 http://www.uniprot.org/uniprot/P17947 denotes PU.1
T11887 2379-2389 http://www.uniprot.org/uniprot/P08659 denotes luciferase
T11886 501-511 http://www.uniprot.org/uniprot/P08659 denotes luciferase
T11885 2041-2049 http://www.uniprot.org/uniprot/P05120 denotes SERPINB2
T11884 2415-2423 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T11883 2198-2206 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T11882 1949-1957 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T11881 978-986 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T11880 854-862 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T11879 483-491 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T11878 46-54 http://www.uniprot.org/uniprot/P05120 denotes SerpinB2
T11877 2502-2506 http://www.uniprot.org/uniprot/P05412 denotes AP-1
T11876 2292-2296 http://www.uniprot.org/uniprot/P05412 denotes AP-1
T11875 1924-1928 http://www.uniprot.org/uniprot/P05412 denotes AP-1
T11874 21-25 http://www.uniprot.org/uniprot/P05412 denotes AP-1

GO-BP

Id Subject Object Predicate Lexical cue
T23804 1750-1769 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activity
T23803 1750-1769 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activity
T23802 1750-1769 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activity
T23801 1750-1769 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activity
T23800 1750-1769 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activity
T11542 2379-2398 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activity
T11541 2379-2398 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activity
T11540 2379-2398 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activity
T11539 2379-2398 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activity
T11538 2379-2398 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activity
T11537 2171-2183 http://purl.obolibrary.org/obo/GO_0032496 denotes LPS response
T11536 2558-2571 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11535 430-443 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11534 335-348 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11533 268-281 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11532 217-230 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11531 118-131 http://purl.obolibrary.org/obo/GO_0006351 denotes Transcription

GO-MF

Id Subject Object Predicate Lexical cue
T23809 1750-1769 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activity
T23808 1750-1769 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activity
T23807 1750-1769 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activity
T23806 1750-1769 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activity
T23805 1750-1769 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activity
T11553 2379-2398 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activity
T11552 2379-2398 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activity
T11551 2379-2398 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activity
T11550 2379-2398 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activity
T11549 2379-2398 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activity
T11548 430-458 http://purl.obolibrary.org/obo/GO_0070491 denotes transcription factor binding
T11547 430-458 http://purl.obolibrary.org/obo/GO_0043425 denotes transcription factor binding
T11546 430-458 http://purl.obolibrary.org/obo/GO_0033613 denotes transcription factor binding
T11545 430-458 http://purl.obolibrary.org/obo/GO_0008134 denotes transcription factor binding
T11544 451-458 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T11543 250-257 http://purl.obolibrary.org/obo/GO_0005488 denotes binding

sentences

Id Subject Object Predicate Lexical cue
T23785 1724-1856 Sentence denotes The results show relative luciferase activity following LPS treatment and represent the mean and SEM of 4–7 independent experiments.
T23784 1406-1723 Sentence denotes Positions of murine SerpinB2 proximal promoter-specific primers, 338/−315 and −5/+19 used in ChIP assays are indicated. (B) RAW 264.7 macrophages were transiently transfected with the indicated murine SerpinB2 promoter-luciferase reporter constructs and either left untreated or treated with 100 ng/ml LPS for 16 hrs.
T23783 1317-1405 Sentence denotes The location of the 5′ ends of the −539, −189 and −87 reporter constructs is also shown.
T23782 1149-1316 Sentence denotes (A) Schematic representation of the −539/+92 region of the murine SerpinB2 promoter with the location of candidate cis-acting regulatory elements indicated with boxes.
T23781 1042-1148 Sentence denotes Identification of cis-acting elements required for the LPS-responsiveness of the murine SerpinB2 promoter.
T11450 2434-2608 Sentence denotes These data show that the C/EBP element, as well as the CRE and both AP-1 cis-acting elements are critical for LPS-inducible transcription from the SerpinB2 proximal promoter.
T11449 2217-2433 Sentence denotes As shown in Fig. 4B, mutation of the CRE at −177/−172 or either of the two AP-1 sites at −106/−100 and −94/−88, completely or significantly reduced LPS-inducible luciferase activity from the murine SerpinB2 promoter.
T11448 1857-2216 Sentence denotes Considering the conserved sequence and position of the CRE and two AP-1 sites in the murine SerpinB2 promoter and their demonstrated involvement in the PMA-responsiveness of the human SERPINB2 promoter [37], these sites were also mutated by nucleotide substitution to investigate whether they played a role in the LPS response of the murine SerpinB2 promoter.
T11447 892-997 Sentence denotes Others have also recently implicated this C/EBP site in LPS-induced activation of the SerpinB2 gene [58].
T11446 717-891 Sentence denotes In contrast, mutation of the C/EBP site (−203/−192) completely eliminated promoter activity, similar to the levels observed for the −189 SerpinB2 promoter deletion construct.
T11445 547-716 Sentence denotes As shown in Fig. 4B, mutation of the consensus E box (−538/−533), PU.1 (−412/−407), or the variant Oct-1 (−296/−288) site did not decrease LPS-induced promoter activity.
T11444 132-546 Sentence denotes To investigate regulatory elements between −539 and −189 essential for LPS-inducible transcription, several candidate binding sites for transcription factors previously reported to mediate LPS-inducible transcription in other genes [57] were targeted by nucleotide substitution designed to disrupt transcription factor binding to the pGLmP-539 murine SerpinB2 promoter-luciferase reporter gene construct (Fig. 4A).
T11443 0-131 Sentence denotes A C/EBP, CRE and Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter are Essential for Optimal LPS-inducible Transcription
T158 0-131 Sentence denotes A C/EBP, CRE and Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter are Essential for Optimal LPS-inducible Transcription
T159 132-546 Sentence denotes To investigate regulatory elements between −539 and −189 essential for LPS-inducible transcription, several candidate binding sites for transcription factors previously reported to mediate LPS-inducible transcription in other genes [57] were targeted by nucleotide substitution designed to disrupt transcription factor binding to the pGLmP-539 murine SerpinB2 promoter-luciferase reporter gene construct (Fig. 4A).
T160 547-716 Sentence denotes As shown in Fig. 4B, mutation of the consensus E box (−538/−533), PU.1 (−412/−407), or the variant Oct-1 (−296/−288) site did not decrease LPS-induced promoter activity.
T161 717-891 Sentence denotes In contrast, mutation of the C/EBP site (−203/−192) completely eliminated promoter activity, similar to the levels observed for the −189 SerpinB2 promoter deletion construct.
T162 892-997 Sentence denotes Others have also recently implicated this C/EBP site in LPS-induced activation of the SerpinB2 gene [58].
T163 998-1148 Sentence denotes 10.1371/journal.pone.0057855.g004 Figure 4 Identification of cis-acting elements required for the LPS-responsiveness of the murine SerpinB2 promoter.
T164 1149-1316 Sentence denotes (A) Schematic representation of the −539/+92 region of the murine SerpinB2 promoter with the location of candidate cis-acting regulatory elements indicated with boxes.
T165 1317-1405 Sentence denotes The location of the 5′ ends of the −539, −189 and −87 reporter constructs is also shown.
T166 1406-1723 Sentence denotes Positions of murine SerpinB2 proximal promoter-specific primers, 338/−315 and −5/+19 used in ChIP assays are indicated. (B) RAW 264.7 macrophages were transiently transfected with the indicated murine SerpinB2 promoter-luciferase reporter constructs and either left untreated or treated with 100 ng/ml LPS for 16 hrs.
T167 1724-1856 Sentence denotes The results show relative luciferase activity following LPS treatment and represent the mean and SEM of 4–7 independent experiments.
T168 1857-2216 Sentence denotes Considering the conserved sequence and position of the CRE and two AP-1 sites in the murine SerpinB2 promoter and their demonstrated involvement in the PMA-responsiveness of the human SERPINB2 promoter [37], these sites were also mutated by nucleotide substitution to investigate whether they played a role in the LPS response of the murine SerpinB2 promoter.
T169 2217-2433 Sentence denotes As shown in Fig. 4B, mutation of the CRE at −177/−172 or either of the two AP-1 sites at −106/−100 and −94/−88, completely or significantly reduced LPS-inducible luciferase activity from the murine SerpinB2 promoter.
T170 2434-2608 Sentence denotes These data show that the C/EBP element, as well as the CRE and both AP-1 cis-acting elements are critical for LPS-inducible transcription from the SerpinB2 proximal promoter.

simple1

Id Subject Object Predicate Lexical cue
T23814 1750-1760 Protein denotes luciferase
T23813 1607-1644 Protein denotes SerpinB2 promoter-luciferase reporter
T23812 1426-1434 Protein denotes SerpinB2
T23811 1215-1223 Protein denotes SerpinB2
T23810 1130-1138 Protein denotes SerpinB2
T11554 46-54 Protein denotes SerpinB2
T11563 2581-2589 Protein denotes SerpinB2
T11562 2415-2423 Protein denotes SerpinB2
T11561 2379-2389 Protein denotes luciferase
T11560 2198-2206 Protein denotes SerpinB2
T11559 2041-2049 Protein denotes SERPINB2
T11558 1949-1957 Protein denotes SerpinB2
T11557 978-986 Protein denotes SerpinB2
T11556 854-862 Protein denotes SerpinB2
T11555 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T23948 1097-1115 Regulation denotes LPS-responsiveness
T23947 1080-1088 Positive_regulation denotes required
T23946 1750-1760 Protein denotes luciferase
T23945 1607-1644 Protein denotes SerpinB2 promoter-luciferase reporter
T23944 1426-1434 Protein denotes SerpinB2
T23943 1215-1223 Protein denotes SerpinB2
T23942 1130-1138 Protein denotes SerpinB2
T11873 2544-2557 Positive_regulation denotes LPS-inducible
T11872 2531-2539 Positive_regulation denotes critical
T11871 2558-2571 Transcription denotes transcription
T11870 2357-2364 Negative_regulation denotes reduced
T11869 2365-2378 Positive_regulation denotes LPS-inducible
T11868 2175-2183 Positive_regulation denotes response
T11867 2159-2163 Regulation denotes role
T11866 2009-2027 Positive_regulation denotes PMA-responsiveness
T11865 960-970 Positive_regulation denotes activation
T11864 948-959 Positive_regulation denotes LPS-induced
T11863 2581-2589 Protein denotes SerpinB2
T11862 2415-2423 Protein denotes SerpinB2
T11861 2379-2389 Protein denotes luciferase
T11860 2198-2206 Protein denotes SerpinB2
T11859 2041-2049 Protein denotes SERPINB2
T11858 1949-1957 Protein denotes SerpinB2
T11857 978-986 Protein denotes SerpinB2
T11856 854-862 Protein denotes SerpinB2
T11855 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene
T11854 46-54 Protein denotes SerpinB2
R8794 T11857 T11865 themeOf SerpinB2,activation
R8795 T11859 T11866 themeOf SERPINB2,PMA-responsiveness
R8796 T11860 T11867 themeOf SerpinB2,role
R8797 T11860 T11868 themeOf SerpinB2,response
R8798 T11861 T11870 themeOf luciferase,reduced
R8799 T11861 T11869 themeOf luciferase,LPS-inducible
R8800 T11862 T11870 themeOf SerpinB2,reduced
R8801 T11863 T11871 themeOf SerpinB2,transcription
R8802 T11865 T11864 themeOf activation,LPS-induced
R8803 T11869 T11870 themeOf LPS-inducible,reduced
R8804 T11871 T11872 themeOf transcription,critical
R8805 T11871 T11873 themeOf transcription,LPS-inducible
R17235 T23942 T23947 themeOf SerpinB2,required
R17236 T23942 T23948 themeOf SerpinB2,LPS-responsiveness

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T11930 2357-2364 Negative_regulation denotes reduced
T11929 960-970 Positive_regulation denotes activation
T11928 451-458 Binding denotes binding
T11927 2581-2589 Protein denotes SerpinB2
T11926 2415-2423 Protein denotes SerpinB2
T11925 2379-2389 Protein denotes luciferase
T11924 2198-2206 Protein denotes SerpinB2
T11923 2041-2049 Protein denotes SERPINB2
T11922 1949-1957 Protein denotes SerpinB2
T11921 978-986 Protein denotes SerpinB2
T11920 854-862 Protein denotes SerpinB2
T11919 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene
T11918 46-54 Protein denotes SerpinB2
T23970 1569-1580 Gene_expression denotes transfected
T23969 1750-1760 Protein denotes luciferase
T23968 1607-1644 Protein denotes SerpinB2 promoter-luciferase reporter
T23967 1426-1434 Protein denotes SerpinB2
T23966 1215-1223 Protein denotes SerpinB2
T23965 1130-1138 Protein denotes SerpinB2
R8816 T11919 T11928 themeOf SerpinB2 promoter-luciferase reporter gene,binding
R8817 T11921 T11929 themeOf SerpinB2,activation
R8818 T11925 T11930 themeOf luciferase,reduced
R17237 T23968 T23970 themeOf SerpinB2 promoter-luciferase reporter,transfected

DLUT931

Id Subject Object Predicate Lexical cue
T11917 2365-2378 Positive_regulation denotes LPS-inducible
T11916 2357-2364 Negative_regulation denotes reduced
T11915 948-959 Positive_regulation denotes LPS-induced
T11914 960-970 Positive_regulation denotes activation
T11913 451-458 Binding denotes binding
T11912 2581-2589 Protein denotes SerpinB2
T11911 2415-2423 Protein denotes SerpinB2
T11910 2379-2389 Protein denotes luciferase
T11909 2198-2206 Protein denotes SerpinB2
T11908 2041-2049 Protein denotes SERPINB2
T11907 1949-1957 Protein denotes SerpinB2
T11906 978-986 Protein denotes SerpinB2
T11905 854-862 Protein denotes SerpinB2
T11904 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene
T11903 46-54 Protein denotes SerpinB2
T23959 1750-1760 Protein denotes luciferase
T23958 1607-1644 Protein denotes SerpinB2 promoter-luciferase reporter
T23957 1426-1434 Protein denotes SerpinB2
T23956 1215-1223 Protein denotes SerpinB2
T23955 1130-1138 Protein denotes SerpinB2
R8809 T11904 T11913 themeOf SerpinB2 promoter-luciferase reporter gene,binding
R8810 T11906 T11914 themeOf SerpinB2,activation
R8811 T11910 T11916 themeOf luciferase,reduced
R8812 T11910 T11917 themeOf luciferase,LPS-inducible
R8813 T11911 T11916 themeOf SerpinB2,reduced
R8814 T11914 T11915 themeOf activation,LPS-induced
R8815 T11917 T11916 themeOf LPS-inducible,reduced

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T23997 1201-1232 Entity denotes of the murine SerpinB2 promoter
T23996 1426-1434 Protein denotes SerpinB2
T23995 1750-1760 Protein denotes luciferase
T23994 1499-1510 Entity denotes ChIP assays
T23993 1310-1315 Entity denotes boxes
T23992 1716-1722 Protein denotes 16 hrs
T23991 1116-1147 Entity denotes of the murine SerpinB2 promoter
T23990 1416-1510 Entity denotes of murine SerpinB2 proximal promoter-specific primers, 338/−315 and −5/+19 used in ChIP assays
T23989 1130-1138 Protein denotes SerpinB2
T23988 1416-1510 Entity denotes of murine SerpinB2 proximal promoter-specific primers, 338/−315 and −5/+19 used in ChIP assays
T23987 1264-1267 Protein denotes cis
T23986 1530-1551 Entity denotes RAW 264.7 macrophages
T23985 1702-1722 Entity denotes ng/ml LPS for 16 hrs
T23984 1215-1223 Protein denotes SerpinB2
T23983 1093-1147 Entity denotes the LPS-responsiveness of the murine SerpinB2 promoter
T23982 1780-1783 Entity denotes LPS
T23981 1600-1655 Protein denotes murine SerpinB2 promoter-luciferase reporter constructs
T12044 899-991 Gene_expression denotes have also recently implicated this C/EBP site in LPS-induced activation of the SerpinB2 gene
T12043 2-131 Regulation denotes C/EBP, CRE and Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter are Essential for Optimal LPS-inducible Transcription
T12042 2-131 Regulation denotes C/EBP, CRE and Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter are Essential for Optimal LPS-inducible Transcription
T12041 2-131 Regulation denotes C/EBP, CRE and Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter are Essential for Optimal LPS-inducible Transcription
T12040 258-368 Regulation denotes sites for transcription factors previously reported to mediate LPS-inducible transcription in other genes [57]
T12039 948-991 Positive_regulation denotes LPS-induced activation of the SerpinB2 gene
T12038 854-862 Protein denotes SerpinB2
T12037 2379-2389 Protein denotes luciferase
T12036 845-880 Entity denotes the −189 SerpinB2 promoter deletion
T12035 577-611 Entity denotes of the consensus E box (−538/−533)
T12034 978-986 Protein denotes SerpinB2
T12033 2292-2296 Protein denotes AP-1
T12032 2041-2049 Protein denotes SERPINB2
T12031 17-77 Entity denotes Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter
T12030 2544-2547 Entity denotes LPS
T12029 791-799 Entity denotes promoter
T12028 2171-2174 Entity denotes LPS
T12027 1908-1915 Protein denotes the CRE
T12026 2485-2492 Protein denotes the CRE
T12025 35-77 Entity denotes the Murine SerpinB2 Gene Proximal Promoter
T12024 934-939 Protein denotes C/EBP
T12023 948-959 Entity denotes LPS-induced
T12022 2065-2076 Entity denotes these sites
T12021 462-471 Protein denotes the pGLmP
T12020 2404-2432 Entity denotes the murine SerpinB2 promoter
T12019 2415-2423 Protein denotes SerpinB2
T12018 646-663 Protein denotes Oct-1 (−296/−288)
T12017 2502-2506 Protein denotes AP-1
T12016 2581-2589 Protein denotes SerpinB2
T12015 2274-2315 Entity denotes either of the two AP-1 sites at −106/−100
T12014 2198-2206 Protein denotes SerpinB2
T12013 971-991 Protein denotes of the SerpinB2 gene
T12012 2187-2215 Entity denotes the murine SerpinB2 promoter
T12011 352-368 Protein denotes other genes [57]
T12010 698-706 Entity denotes promoter
T12009 1924-1928 Protein denotes AP-1
T12008 2-7 Protein denotes C/EBP
T12007 9-12 Protein denotes CRE
T12006 2459-2464 Protein denotes C/EBP
T12005 1949-1957 Protein denotes SerpinB2
T12004 2247-2257 Protein denotes of the CRE
T12003 21-25 Protein denotes AP-1
T12002 1938-1966 Entity denotes the murine SerpinB2 promoter
T12001 929-944 Entity denotes this C/EBP site
T12000 537-540 Protein denotes Fig
T11999 613-629 Protein denotes PU.1 (−412/−407)
T11998 46-54 Protein denotes SerpinB2
T11997 2098-2108 Entity denotes nucleotide
T11996 664-668 Entity denotes site
T11995 1920-1934 Entity denotes two AP-1 sites
T11994 2002-2063 Entity denotes in the PMA-responsiveness of the human SERPINB2 promoter [37]
T11993 386-396 Entity denotes nucleotide
T11992 746-751 Protein denotes C/EBP
T11991 577-611 Entity denotes of the consensus E box (−538/−533)
T11990 2028-2063 Entity denotes of the human SERPINB2 promoter [37]
T11989 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene
T11988 2281-2315 Entity denotes of the two AP-1 sites at −106/−100
T11987 739-756 Entity denotes of the C/EBP site
T11986 35-77 Protein denotes the Murine SerpinB2 Gene Proximal Promoter
T11985 2229-2232 Protein denotes Fig
T11984 258-368 Entity denotes sites for transcription factors previously reported to mediate LPS-inducible transcription in other genes [57]
T11983 2577-2607 Entity denotes the SerpinB2 proximal promoter
R8839 T11984 T12040 causeOf sites for transcription factors previously reported to mediate LPS-inducible transcription in other genes [57],sites for transcription factors previously reported to mediate LPS-inducible transcription in other genes [57]
R8840 T12007 T12043 causeOf CRE,"C/EBP, CRE and Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter are Essential for Optimal LPS-inducible Transcription"
R8841 T12008 T12041 causeOf C/EBP,"C/EBP, CRE and Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter are Essential for Optimal LPS-inducible Transcription"
R8842 T12013 T12039 themeOf of the SerpinB2 gene,LPS-induced activation of the SerpinB2 gene
R8843 T12024 T12044 themeOf C/EBP,have also recently implicated this C/EBP site in LPS-induced activation of the SerpinB2 gene
R8844 T12031 T12042 causeOf Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter,"C/EBP, CRE and Two AP-1 Sites in the Murine SerpinB2 Gene Proximal Promoter are Essential for Optimal LPS-inducible Transcription"
R17238 T23991 T23989 partOf of the murine SerpinB2 promoter,SerpinB2
R17239 T23997 T23984 partOf of the murine SerpinB2 promoter,SerpinB2

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T11956 2531-2539 Positive_regulation denotes critical
T11955 2558-2571 Transcription denotes transcription
T11954 2581-2607 Protein denotes SerpinB2 proximal promoter
T11953 2459-2472 Protein denotes C/EBP element
T11952 2357-2364 Negative_regulation denotes reduced
T11951 2369-2378 Positive_regulation denotes inducible
T11950 2408-2432 Protein denotes murine SerpinB2 promoter
T11949 2379-2389 Protein denotes luciferase
T11948 2365-2368 Protein denotes LPS
T11947 2292-2302 Protein denotes AP-1 sites
T11946 2229-2232 Protein denotes Fig
T11945 2159-2163 Regulation denotes role
T11944 2175-2183 Positive_regulation denotes response
T11943 2191-2215 Protein denotes murine SerpinB2 promoter
T11942 1942-1966 Protein denotes murine SerpinB2 promoter
T11941 1924-1934 Protein denotes AP-1 sites
T11940 934-944 Protein denotes C/EBP site
T11939 746-756 Protein denotes C/EBP site
T11938 646-651 Protein denotes Oct-1
T11937 559-562 Protein denotes Fig
T11936 451-458 Binding denotes binding
T11935 537-544 Protein denotes Fig. 4A
T11934 501-511 Protein denotes luciferase
T11933 466-500 Protein denotes pGLmP-539 murine SerpinB2 promoter
T11932 118-131 Transcription denotes Transcription
T11931 2-7 Protein denotes C/EBP
T23975 1750-1760 Protein denotes luciferase
T23974 1625-1635 Protein denotes luciferase
T23973 1600-1624 Protein denotes murine SerpinB2 promoter
T23972 1208-1232 Protein denotes murine SerpinB2 promoter
T23971 1123-1147 Protein denotes murine SerpinB2 promoter
R8819 T11931 T11932 themeOf C/EBP,Transcription
R8820 T11934 T11936 themeOf luciferase,binding
R8821 T11943 T11944 themeOf murine SerpinB2 promoter,response
R8822 T11944 T11945 themeOf response,role
R8823 T11948 T11951 causeOf LPS,inducible
R8824 T11949 T11951 themeOf luciferase,inducible
R8825 T11951 T11952 themeOf inducible,reduced
R8826 T11953 T11956 causeOf C/EBP element,critical
R8827 T11954 T11955 themeOf SerpinB2 proximal promoter,transcription
R8828 T11955 T11956 themeOf transcription,critical

testone

Id Subject Object Predicate Lexical cue
T23769 1750-1760 Protein denotes luciferase
T23768 1607-1644 Protein denotes SerpinB2 promoter-luciferase reporter
T23767 1426-1434 Protein denotes SerpinB2
T23766 1215-1223 Protein denotes SerpinB2
T23765 1130-1138 Protein denotes SerpinB2
T11416 2369-2378 Positive_regulation denotes inducible
T11415 2357-2364 Negative_regulation denotes reduced
T11414 952-959 Positive_regulation denotes induced
T11413 752-756 Entity denotes site
T11412 451-458 Binding denotes binding
T11411 2581-2589 Protein denotes SerpinB2
T11410 2415-2423 Protein denotes SerpinB2
T11409 2379-2389 Protein denotes luciferase
T11408 2198-2206 Protein denotes SerpinB2
T11407 2041-2049 Protein denotes SERPINB2
T11406 1949-1957 Protein denotes SerpinB2
T11405 978-986 Protein denotes SerpinB2
T11404 854-862 Protein denotes SerpinB2
T11403 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene
T11402 46-54 Protein denotes SerpinB2
R8428 T11403 T11412 themeOf SerpinB2 promoter-luciferase reporter gene,binding
R8429 T11409 T11416 themeOf luciferase,inducible
R8430 T11416 T11415 themeOf inducible,reduced

test3

Id Subject Object Predicate Lexical cue
T23780 1770-1779 Positive_regulation denotes following
T23779 1750-1760 Protein denotes luciferase
T23778 1607-1644 Protein denotes SerpinB2 promoter-luciferase reporter
T23777 1426-1434 Protein denotes SerpinB2
T23776 1215-1223 Protein denotes SerpinB2
T23775 1130-1138 Protein denotes SerpinB2
T23774 1750-1760 Protein denotes luciferase
T23773 1607-1644 Protein denotes SerpinB2 promoter-luciferase reporter
T23772 1426-1434 Protein denotes SerpinB2
T23771 1215-1223 Protein denotes SerpinB2
T23770 1130-1138 Protein denotes SerpinB2
T11442 2581-2589 Protein denotes SerpinB2
T11441 2415-2423 Protein denotes SerpinB2
T11440 2379-2389 Protein denotes luciferase
T11439 2369-2378 Positive_regulation denotes inducible
T11438 2357-2364 Negative_regulation denotes reduced
T11437 2198-2206 Protein denotes SerpinB2
T11436 2041-2049 Protein denotes SERPINB2
T11435 1949-1957 Protein denotes SerpinB2
T11434 1926-1927 Entity denotes -
T11433 978-986 Protein denotes SerpinB2
T11432 960-970 Positive_regulation denotes activation
T11431 952-959 Positive_regulation denotes induced
T11430 854-862 Protein denotes SerpinB2
T11429 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene
T11428 451-458 Binding denotes binding
T11427 46-54 Protein denotes SerpinB2
T11426 2581-2589 Protein denotes SerpinB2
T11425 2415-2423 Protein denotes SerpinB2
T11424 2379-2389 Protein denotes luciferase
T11423 2198-2206 Protein denotes SerpinB2
T11422 2041-2049 Protein denotes SERPINB2
T11421 1949-1957 Protein denotes SerpinB2
T11420 978-986 Protein denotes SerpinB2
T11419 854-862 Protein denotes SerpinB2
T11418 483-525 Protein denotes SerpinB2 promoter-luciferase reporter gene
T11417 46-54 Protein denotes SerpinB2
R8431 T11429 T11428 themeOf SerpinB2 promoter-luciferase reporter gene,binding
R8432 T11432 T11431 themeOf activation,induced
R8433 T11433 T11432 themeOf SerpinB2,activation
R8434 T11439 T11438 themeOf inducible,reduced
R8435 T11440 T11439 themeOf luciferase,inducible
R17106 T23779 T23780 themeOf luciferase,following