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{"project":"simple1","denotations":[{"id":"T9051","span":{"begin":484,"end":492},"obj":"Protein"},{"id":"T9050","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T9049","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T9048","span":{"begin":47,"end":55},"obj":"Protein"}],"text":"When RAW264.7 macrophages were exposed to LPS, SerpinB2 mRNA was detectable as early as 30 min following LPS challenge, reaching maximal levels at 24 hrs (Fig. 1A). A similar strong induction of LPS-inducible SerpinB2 mRNA expression has been reported previously in murine peritoneal macrophages and human peripheral blood mononuclear cells [4]; [32]. LPS-induced SerpinB2 expression involves both an increase in gene transcription and stabilization of the mRNA [5]; [29]; [42]–[44]. SerpinB2 protein expression was also induced as has been reported in other cell types [31], and detectable after 8 hrs of LPS treatment (Fig. 1)."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T9193","span":{"begin":521,"end":528},"obj":"Positive_regulation"},{"id":"T9192","span":{"begin":501,"end":511},"obj":"Gene_expression"},{"id":"T9191","span":{"begin":352,"end":363},"obj":"Positive_regulation"},{"id":"T9190","span":{"begin":373,"end":383},"obj":"Gene_expression"},{"id":"T9189","span":{"begin":182,"end":191},"obj":"Positive_regulation"},{"id":"T9188","span":{"begin":223,"end":233},"obj":"Transcription"},{"id":"T9187","span":{"begin":195,"end":208},"obj":"Positive_regulation"},{"id":"T9186","span":{"begin":65,"end":75},"obj":"Transcription"},{"id":"T9185","span":{"begin":484,"end":492},"obj":"Protein"},{"id":"T9184","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T9183","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T9182","span":{"begin":47,"end":55},"obj":"Protein"}],"relations":[{"id":"R6740","pred":"themeOf","subj":"T9182","obj":"T9186"},{"id":"R6741","pred":"themeOf","subj":"T9183","obj":"T9188"},{"id":"R6742","pred":"themeOf","subj":"T9184","obj":"T9190"},{"id":"R6743","pred":"themeOf","subj":"T9185","obj":"T9192"},{"id":"R6744","pred":"themeOf","subj":"T9188","obj":"T9189"},{"id":"R6745","pred":"themeOf","subj":"T9188","obj":"T9187"},{"id":"R6746","pred":"themeOf","subj":"T9190","obj":"T9191"},{"id":"R6747","pred":"themeOf","subj":"T9192","obj":"T9193"}],"text":"When RAW264.7 macrophages were exposed to LPS, SerpinB2 mRNA was detectable as early as 30 min following LPS challenge, reaching maximal levels at 24 hrs (Fig. 1A). A similar strong induction of LPS-inducible SerpinB2 mRNA expression has been reported previously in murine peritoneal macrophages and human peripheral blood mononuclear cells [4]; [32]. LPS-induced SerpinB2 expression involves both an increase in gene transcription and stabilization of the mRNA [5]; [29]; [42]–[44]. SerpinB2 protein expression was also induced as has been reported in other cell types [31], and detectable after 8 hrs of LPS treatment (Fig. 1)."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T9232","span":{"begin":521,"end":528},"obj":"Positive_regulation"},{"id":"T9231","span":{"begin":501,"end":511},"obj":"Gene_expression"},{"id":"T9230","span":{"begin":352,"end":363},"obj":"Positive_regulation"},{"id":"T9229","span":{"begin":373,"end":383},"obj":"Gene_expression"},{"id":"T9228","span":{"begin":223,"end":233},"obj":"Transcription"},{"id":"T9227","span":{"begin":195,"end":208},"obj":"Positive_regulation"},{"id":"T9226","span":{"begin":182,"end":191},"obj":"Positive_regulation"},{"id":"T9225","span":{"begin":484,"end":492},"obj":"Protein"},{"id":"T9224","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T9223","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T9222","span":{"begin":47,"end":55},"obj":"Protein"}],"relations":[{"id":"R6760","pred":"themeOf","subj":"T9223","obj":"T9228"},{"id":"R6761","pred":"themeOf","subj":"T9224","obj":"T9229"},{"id":"R6762","pred":"themeOf","subj":"T9225","obj":"T9231"},{"id":"R6763","pred":"themeOf","subj":"T9228","obj":"T9226"},{"id":"R6764","pred":"themeOf","subj":"T9228","obj":"T9227"},{"id":"R6765","pred":"themeOf","subj":"T9229","obj":"T9230"},{"id":"R6766","pred":"themeOf","subj":"T9231","obj":"T9232"}],"text":"When RAW264.7 macrophages were exposed to LPS, SerpinB2 mRNA was detectable as early as 30 min following LPS challenge, reaching maximal levels at 24 hrs (Fig. 1A). A similar strong induction of LPS-inducible SerpinB2 mRNA expression has been reported previously in murine peritoneal macrophages and human peripheral blood mononuclear cells [4]; [32]. LPS-induced SerpinB2 expression involves both an increase in gene transcription and stabilization of the mRNA [5]; [29]; [42]–[44]. SerpinB2 protein expression was also induced as has been reported in other cell types [31], and detectable after 8 hrs of LPS treatment (Fig. 1)."}

{"project":"DLUT931","denotations":[{"id":"T9212","span":{"begin":521,"end":528},"obj":"Positive_regulation"},{"id":"T9211","span":{"begin":501,"end":511},"obj":"Gene_expression"},{"id":"T9210","span":{"begin":352,"end":363},"obj":"Positive_regulation"},{"id":"T9209","span":{"begin":373,"end":383},"obj":"Gene_expression"},{"id":"T9208","span":{"begin":195,"end":208},"obj":"Positive_regulation"},{"id":"T9207","span":{"begin":182,"end":191},"obj":"Positive_regulation"},{"id":"T9206","span":{"begin":223,"end":233},"obj":"Transcription"},{"id":"T9205","span":{"begin":56,"end":60},"obj":"Transcription"},{"id":"T9203","span":{"begin":484,"end":492},"obj":"Protein"},{"id":"T9202","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T9201","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T9200","span":{"begin":47,"end":55},"obj":"Protein"}],"relations":[{"id":"R6749","pred":"themeOf","subj":"T9200","obj":"T9205"},{"id":"R6750","pred":"themeOf","subj":"T9201","obj":"T9206"},{"id":"R6751","pred":"themeOf","subj":"T9202","obj":"T9209"},{"id":"R6752","pred":"themeOf","subj":"T9203","obj":"T9211"},{"id":"R6753","pred":"themeOf","subj":"T9206","obj":"T9207"},{"id":"R6754","pred":"themeOf","subj":"T9206","obj":"T9208"},{"id":"R6755","pred":"themeOf","subj":"T9209","obj":"T9210"},{"id":"R6756","pred":"themeOf","subj":"T9211","obj":"T9212"}],"text":"When RAW264.7 macrophages were exposed to LPS, SerpinB2 mRNA was detectable as early as 30 min following LPS challenge, reaching maximal levels at 24 hrs (Fig. 1A). A similar strong induction of LPS-inducible SerpinB2 mRNA expression has been reported previously in murine peritoneal macrophages and human peripheral blood mononuclear cells [4]; [32]. LPS-induced SerpinB2 expression involves both an increase in gene transcription and stabilization of the mRNA [5]; [29]; [42]–[44]. SerpinB2 protein expression was also induced as has been reported in other cell types [31], and detectable after 8 hrs of LPS treatment (Fig. 1)."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T9282","span":{"begin":398,"end":431},"obj":"Positive_regulation"},{"id":"T9281","span":{"begin":192,"end":233},"obj":"Gene_expression"},{"id":"T9280","span":{"begin":352,"end":383},"obj":"Gene_expression"},{"id":"T9279","span":{"begin":410,"end":431},"obj":"Transcription"},{"id":"T9277","span":{"begin":105,"end":108},"obj":"Entity"},{"id":"T9276","span":{"begin":300,"end":340},"obj":"Entity"},{"id":"T9275","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T9274","span":{"begin":450,"end":461},"obj":"Protein"},{"id":"T9273","span":{"begin":484,"end":492},"obj":"Protein"},{"id":"T9272","span":{"begin":352,"end":363},"obj":"Entity"},{"id":"T9271","span":{"begin":56,"end":60},"obj":"Protein"},{"id":"T9269","span":{"begin":413,"end":417},"obj":"Protein"},{"id":"T9268","span":{"begin":553,"end":575},"obj":"Entity"},{"id":"T9267","span":{"begin":484,"end":531},"obj":"Protein"},{"id":"T9266","span":{"begin":606,"end":609},"obj":"Entity"},{"id":"T9265","span":{"begin":266,"end":295},"obj":"Entity"},{"id":"T9264","span":{"begin":580,"end":628},"obj":"Protein"},{"id":"T9263","span":{"begin":147,"end":163},"obj":"Protein"},{"id":"T9262","span":{"begin":47,"end":90},"obj":"Protein"},{"id":"T9261","span":{"begin":209,"end":222},"obj":"Protein"},{"id":"T9260","span":{"begin":5,"end":25},"obj":"Entity"},{"id":"T9259","span":{"begin":42,"end":46},"obj":"Entity"},{"id":"T9257","span":{"begin":209,"end":217},"obj":"Protein"}],"relations":[{"id":"R6781","pred":"themeOf","subj":"T9261","obj":"T9281"},{"id":"R6782","pred":"themeOf","subj":"T9269","obj":"T9279"},{"id":"R6783","pred":"themeOf","subj":"T9275","obj":"T9280"},{"id":"R6784","pred":"themeOf","subj":"T9279","obj":"T9282"}],"text":"When RAW264.7 macrophages were exposed to LPS, SerpinB2 mRNA was detectable as early as 30 min following LPS challenge, reaching maximal levels at 24 hrs (Fig. 1A). A similar strong induction of LPS-inducible SerpinB2 mRNA expression has been reported previously in murine peritoneal macrophages and human peripheral blood mononuclear cells [4]; [32]. LPS-induced SerpinB2 expression involves both an increase in gene transcription and stabilization of the mRNA [5]; [29]; [42]–[44]. SerpinB2 protein expression was also induced as has been reported in other cell types [31], and detectable after 8 hrs of LPS treatment (Fig. 1)."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T9244","span":{"begin":521,"end":528},"obj":"Positive_regulation"},{"id":"T9243","span":{"begin":501,"end":511},"obj":"Gene_expression"},{"id":"T9242","span":{"begin":484,"end":500},"obj":"Protein"},{"id":"T9241","span":{"begin":352,"end":363},"obj":"Positive_regulation"},{"id":"T9240","span":{"begin":373,"end":383},"obj":"Gene_expression"},{"id":"T9239","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T9238","span":{"begin":182,"end":191},"obj":"Positive_regulation"},{"id":"T9237","span":{"begin":195,"end":208},"obj":"Positive_regulation"},{"id":"T9236","span":{"begin":223,"end":233},"obj":"Gene_expression"},{"id":"T9235","span":{"begin":209,"end":222},"obj":"Protein"},{"id":"T9234","span":{"begin":47,"end":60},"obj":"Protein"}],"relations":[{"id":"R6767","pred":"themeOf","subj":"T9235","obj":"T9236"},{"id":"R6768","pred":"themeOf","subj":"T9236","obj":"T9237"},{"id":"R6769","pred":"themeOf","subj":"T9237","obj":"T9238"},{"id":"R6770","pred":"themeOf","subj":"T9239","obj":"T9240"},{"id":"R6771","pred":"themeOf","subj":"T9240","obj":"T9241"},{"id":"R6772","pred":"themeOf","subj":"T9242","obj":"T9243"},{"id":"R6773","pred":"themeOf","subj":"T9243","obj":"T9244"}],"text":"When RAW264.7 macrophages were exposed to LPS, SerpinB2 mRNA was detectable as early as 30 min following LPS challenge, reaching maximal levels at 24 hrs (Fig. 1A). A similar strong induction of LPS-inducible SerpinB2 mRNA expression has been reported previously in murine peritoneal macrophages and human peripheral blood mononuclear cells [4]; [32]. LPS-induced SerpinB2 expression involves both an increase in gene transcription and stabilization of the mRNA [5]; [29]; [42]–[44]. SerpinB2 protein expression was also induced as has been reported in other cell types [31], and detectable after 8 hrs of LPS treatment (Fig. 1)."}

{"project":"testone","denotations":[{"id":"T8993","span":{"begin":501,"end":511},"obj":"Gene_expression"},{"id":"T8992","span":{"begin":356,"end":363},"obj":"Positive_regulation"},{"id":"T8991","span":{"begin":218,"end":233},"obj":"Transcription"},{"id":"T8990","span":{"begin":199,"end":208},"obj":"Positive_regulation"},{"id":"T8989","span":{"begin":182,"end":191},"obj":"Positive_regulation"},{"id":"T8988","span":{"begin":95,"end":104},"obj":"Positive_regulation"},{"id":"T8987","span":{"begin":484,"end":492},"obj":"Protein"},{"id":"T8986","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T8985","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T8984","span":{"begin":47,"end":55},"obj":"Protein"}],"relations":[{"id":"R6588","pred":"themeOf","subj":"T8985","obj":"T8991"},{"id":"R6589","pred":"themeOf","subj":"T8987","obj":"T8993"},{"id":"R6590","pred":"themeOf","subj":"T8991","obj":"T8990"},{"id":"R6591","pred":"themeOf","subj":"T8991","obj":"T8989"}],"text":"When RAW264.7 macrophages were exposed to LPS, SerpinB2 mRNA was detectable as early as 30 min following LPS challenge, reaching maximal levels at 24 hrs (Fig. 1A). A similar strong induction of LPS-inducible SerpinB2 mRNA expression has been reported previously in murine peritoneal macrophages and human peripheral blood mononuclear cells [4]; [32]. LPS-induced SerpinB2 expression involves both an increase in gene transcription and stabilization of the mRNA [5]; [29]; [42]–[44]. SerpinB2 protein expression was also induced as has been reported in other cell types [31], and detectable after 8 hrs of LPS treatment (Fig. 1)."}

{"project":"test3","denotations":[{"id":"T9011","span":{"begin":521,"end":528},"obj":"Positive_regulation"},{"id":"T9010","span":{"begin":501,"end":511},"obj":"Gene_expression"},{"id":"T9009","span":{"begin":484,"end":492},"obj":"Protein"},{"id":"T9008","span":{"begin":373,"end":383},"obj":"Gene_expression"},{"id":"T9007","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T9006","span":{"begin":356,"end":363},"obj":"Positive_regulation"},{"id":"T9005","span":{"begin":218,"end":233},"obj":"Transcription"},{"id":"T9004","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T9003","span":{"begin":199,"end":208},"obj":"Positive_regulation"},{"id":"T9002","span":{"begin":182,"end":191},"obj":"Positive_regulation"},{"id":"T9001","span":{"begin":95,"end":104},"obj":"Positive_regulation"},{"id":"T9000","span":{"begin":47,"end":55},"obj":"Protein"},{"id":"T8998","span":{"begin":484,"end":492},"obj":"Protein"},{"id":"T8997","span":{"begin":364,"end":372},"obj":"Protein"},{"id":"T8996","span":{"begin":209,"end":217},"obj":"Protein"},{"id":"T8995","span":{"begin":47,"end":55},"obj":"Protein"}],"relations":[{"id":"R6592","pred":"themeOf","subj":"T9004","obj":"T9005"},{"id":"R6593","pred":"themeOf","subj":"T9005","obj":"T9003"},{"id":"R6594","pred":"themeOf","subj":"T9005","obj":"T9002"},{"id":"R6595","pred":"themeOf","subj":"T9007","obj":"T9008"},{"id":"R6596","pred":"themeOf","subj":"T9008","obj":"T9006"},{"id":"R6597","pred":"themeOf","subj":"T9009","obj":"T9010"},{"id":"R6598","pred":"themeOf","subj":"T9010","obj":"T9011"}],"text":"When RAW264.7 macrophages were exposed to LPS, SerpinB2 mRNA was detectable as early as 30 min following LPS challenge, reaching maximal levels at 24 hrs (Fig. 1A). A similar strong induction of LPS-inducible SerpinB2 mRNA expression has been reported previously in murine peritoneal macrophages and human peripheral blood mononuclear cells [4]; [32]. LPS-induced SerpinB2 expression involves both an increase in gene transcription and stabilization of the mRNA [5]; [29]; [42]–[44]. SerpinB2 protein expression was also induced as has been reported in other cell types [31], and detectable after 8 hrs of LPS treatment (Fig. 1)."}