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PMC:3586680 / 89-1077 JSONTXT

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test3

Id Subject Object Predicate Lexical cue
T78 899-902 Protein denotes p53
T77 856-860 Protein denotes WWOX
T76 823-827 Protein denotes WWOX
T75 770-773 Protein denotes p53
T74 704-708 Protein denotes WWOX
T73 696-699 Protein denotes p53
T72 633-636 Protein denotes p53
T71 604-608 Binding denotes bind
T70 576-580 Protein denotes WWOX
T69 571-574 Protein denotes p53
T68 488-492 Protein denotes WWOX
T67 293-297 Protein denotes WWOX
T66 285-289 Negative_regulation denotes Loss
T65 212-216 Protein denotes WOX1
T64 205-208 Protein denotes FOR
T63 199-203 Protein denotes WWOX
T62 163-198 Protein denotes WW domain-containing oxidoreductase
T61 17-20 Protein denotes p53
T58 899-902 Protein denotes p53
T57 856-860 Protein denotes WWOX
T56 823-827 Protein denotes WWOX
T55 770-773 Protein denotes p53
T54 704-708 Protein denotes WWOX
T53 696-699 Protein denotes p53
T52 633-636 Protein denotes p53
T51 576-580 Protein denotes WWOX
T50 571-574 Protein denotes p53
T49 488-492 Protein denotes WWOX
T48 293-297 Protein denotes WWOX
T47 212-216 Protein denotes WOX1
T46 205-208 Protein denotes FOR
T45 199-203 Protein denotes WWOX
T44 163-198 Protein denotes WW domain-containing oxidoreductase
T43 17-20 Protein denotes p53
R5 T63 T64 themeOf WWOX,FOR
R6 T64 T62 equivalentTo FOR,WW domain-containing oxidoreductase
R7 T70 T71 themeOf WWOX,bind
R8 T72 T71 themeOf p53,bind

testone

Id Subject Object Predicate Lexical cue
T40 604-608 Binding denotes bind
T39 432-440 Negative_regulation denotes blockade
T38 303-313 Gene_expression denotes expression
T37 285-289 Negative_regulation denotes Loss
T36 899-902 Protein denotes p53
T35 856-860 Protein denotes WWOX
T34 823-827 Protein denotes WWOX
T33 770-773 Protein denotes p53
T32 704-708 Protein denotes WWOX
T31 696-699 Protein denotes p53
T30 633-636 Protein denotes p53
T29 576-580 Protein denotes WWOX
T28 571-574 Protein denotes p53
T27 488-492 Protein denotes WWOX
T26 293-297 Protein denotes WWOX
T25 212-216 Protein denotes WOX1
T24 205-208 Protein denotes FOR
T23 199-203 Protein denotes WWOX
T22 163-198 Protein denotes WW domain-containing oxidoreductase
T21 17-20 Protein denotes p53
R1 T26 T38 themeOf WWOX,expression
R2 T29 T40 themeOf WWOX,bind
R4 T38 T37 themeOf expression,Loss
R3 T30 T40 themeOf p53,bind

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T496 914-924 Negative_regulation denotes deficiency
T495 899-902 Protein denotes p53
T494 788-796 Regulation denotes modulate
T493 823-827 Protein denotes WWOX
T492 770-773 Protein denotes p53
T491 704-708 Protein denotes WWOX
T490 696-699 Protein denotes p53
T489 604-608 Binding denotes bind
T488 604-608 Binding denotes bind
T487 633-636 Protein denotes p53
T486 576-580 Protein denotes WWOX
T485 464-474 Gene_expression denotes expression
T484 483-492 Protein denotes type WWOX
T483 432-440 Negative_regulation denotes blockade
T482 285-289 Negative_regulation denotes Loss
T481 303-313 Gene_expression denotes expression
T480 293-302 Protein denotes WWOX gene
T479 212-216 Protein denotes WOX1
T478 205-208 Protein denotes FOR
T477 184-203 Protein denotes oxidoreductase WWOX
T476 17-20 Protein denotes p53
R239 T480 T481 themeOf WWOX gene,expression
R240 T481 T482 themeOf expression,Loss
R241 T482 T483 themeOf Loss,blockade
R242 T484 T485 themeOf type WWOX,expression
R243 T486 T488 themeOf WWOX,bind
R244 T486 T489 themeOf WWOX,bind
R245 T487 T489 themeOf p53,bind
R246 T492 T494 causeOf p53,modulate
R247 T493 T494 themeOf WWOX,modulate
R248 T495 T496 themeOf p53,deficiency

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T729 987-988 . denotes .
T728 982-987 NN denotes death
T727 977-981 NN denotes cell
T726 973-976 NNP denotes GBM
T725 966-972 VB denotes induce
T724 962-965 CC denotes and
T723 951-961 NN denotes resistance
T722 947-950 NNP denotes TMZ
T721 938-946 VB denotes overcome
T720 935-937 TO denotes to
T719 928-934 VBN denotes needed
T718 925-927 VBZ denotes is
T717 914-924 NN denotes deficiency
T716 903-913 JJ denotes functional
T715 899-902 NN denotes p53
T713 887-892 NNS denotes drugs
T712 875-886 JJ denotes therapeutic
T711 872-874 IN denotes by
T710 861-871 NN denotes activation
T709 856-860 NNP denotes WWOX
T708 845-855 VBG denotes triggering
T707 840-844 IN denotes that
T706 832-839 VBP denotes propose
T705 829-831 PRP denotes We
T704 827-828 . denotes .
T703 823-827 NNP denotes WWOX
T702 820-822 IN denotes of
T701 811-819 NN denotes function
T700 801-810 JJ denotes apoptotic
T699 797-800 DT denotes the
T698 788-796 VBP denotes modulate
T697 786-787 , denotes ,
T696 778-786 NNS denotes isoforms
T695 775-777 CC denotes or
T694 773-774 , denotes ,
T693 770-773 NN denotes p53
T692 763-769 JJ denotes mutant
T691 759-762 CC denotes and
T690 754-758 NN denotes type
T689 749-753 JJ denotes wild
T688 744-748 WDT denotes that
T687 734-743 NNS denotes scenarios
T686 724-733 JJ denotes potential
T685 714-723 VB denotes postulate
T684 710-713 CC denotes and
T683 708-709 , denotes ,
T682 704-708 NNP denotes WWOX
T681 700-703 CC denotes and
T680 696-699 NN denotes p53
T679 693-695 IN denotes in
T678 683-692 NN denotes knowledge
T677 675-682 VBN denotes updated
T676 671-674 DT denotes the
T675 667-670 IN denotes for
T674 658-666 NN denotes overview
T673 655-657 DT denotes an
T672 647-654 VBP denotes provide
T671 644-646 PRP denotes we
T670 642-643 , denotes ,
T669 638-642 RB denotes Here
T668 636-637 . denotes .
T667 633-636 NN denotes p53
T666 628-632 NN denotes type
T665 623-627 JJ denotes wild
T664 613-622 VB denotes stabilize
T663 609-612 CC denotes and
T662 604-608 NN denotes bind
T661 593-603 RB denotes physically
T660 590-592 TO denotes to
T659 584-589 VBN denotes known
T658 581-583 VBZ denotes is
T657 576-580 NNP denotes WWOX
T656 574-575 . denotes .
T655 571-574 NN denotes p53
T654 564-570 JJ denotes mutant
T653 554-563 VBG denotes harboring
T652 548-553 NNS denotes cells
T651 535-547 NN denotes glioblastoma
T650 529-534 JJ denotes human
T649 526-528 IN denotes in
T648 516-525 NN denotes apoptosis
T647 508-515 VBZ denotes induces
T646 493-507 RB denotes preferentially
T645 488-492 NNP denotes WWOX
T644 483-487 NN denotes type
T643 478-482 JJ denotes wild
T642 475-477 IN denotes of
T641 464-474 NN denotes expression
T640 456-463 JJ denotes ectopic
T639 454-455 , denotes ,
T638 442-454 RB denotes Intriguingly
T637 440-441 . denotes .
T636 432-440 NN denotes blockade
T635 418-431 JJ denotes translational
T634 414-417 CC denotes and
T633 412-413 , denotes ,
T632 401-412 NNS denotes alterations
T631 393-400 JJ denotes genetic
T630 391-392 , denotes ,
T629 375-391 NN denotes hypermethylation
T628 366-374 NN denotes promoter
T627 363-365 TO denotes to
T626 359-362 JJ denotes due
T625 353-358 NNS denotes cells
T624 346-352 NN denotes cancer
T623 336-345 JJ denotes malignant
T622 333-335 IN denotes in
T621 328-332 VBN denotes seen
T620 317-327 RB denotes frequently
T619 314-316 VBZ denotes is
T618 303-313 NN denotes expression
T616 293-297 NNP denotes WWOX
T615 290-292 IN denotes of
T614 285-289 NN denotes Loss
T613 283-284 . denotes .
T612 273-283 NN denotes suppressor
T611 267-272 NN denotes tumor
T610 265-266 DT denotes a
T609 262-264 IN denotes as
T608 251-261 VBN denotes considered
T607 248-250 VBZ denotes is
T606 244-247 CC denotes and
T605 236-243 NN denotes protein
T604 223-235 JJ denotes proapoptotic
T603 221-222 DT denotes a
T602 218-220 VBZ denotes is
T601 216-217 -RRB- denotes )
T600 212-216 CD denotes WOX1
T599 209-211 CC denotes or
T598 205-208 IN denotes FOR
T597 204-205 -LRB- denotes (
T596 199-203 NNP denotes WWOX
T595 184-198 NN denotes oxidoreductase
T594 166-183 JJ denotes domain-containing
T593 163-165 NNP denotes WW
T592 161-162 . denotes .
T591 156-161 NNS denotes drugs
T590 144-155 JJ denotes therapeutic
T589 140-143 CC denotes and
T588 138-139 -RRB- denotes )
T587 135-138 NNP denotes TMZ
T586 134-135 -LRB- denotes (
T585 121-133 VB denotes temozolomide
T584 118-120 TO denotes to
T583 107-117 NN denotes resistance
T582 104-106 TO denotes to
T581 102-103 , denotes ,
T580 98-102 NN denotes part
T579 95-97 IN denotes in
T578 93-94 , denotes ,
T577 83-93 VB denotes contribute
T576 80-82 TO denotes to
T575 72-79 VBZ denotes appears
T574 68-71 CC denotes and
T573 66-67 -RRB- denotes )
T572 62-66 NNS denotes GBMs
T571 61-62 -LRB- denotes (
T570 47-60 NNS denotes glioblastomas
T569 44-46 IN denotes in
T568 36-43 VBN denotes mutated
T567 25-35 RB denotes frequently
T566 21-24 VBP denotes are
T565 17-20 NN denotes p53
T564 6-16 NN denotes suppressor
T563 0-5 NNP denotes Tumor
T617 298-302 NN denotes gene
T714 893-898 IN denotes under
R395 T683 T682 punct ",",WWOX
R276 T563 T565 compound Tumor,p53
R277 T564 T565 compound suppressor,p53
R279 T566 T568 auxpass are,mutated
R280 T567 T568 advmod frequently,mutated
R281 T568 T568 ROOT mutated,mutated
R282 T569 T568 prep in,mutated
R283 T570 T569 pobj glioblastomas,in
R284 T571 T572 punct (,GBMs
R285 T572 T570 appos GBMs,glioblastomas
R286 T573 T568 punct ),mutated
R287 T574 T568 cc and,mutated
R288 T575 T568 conj appears,mutated
R289 T576 T577 aux to,contribute
R290 T577 T575 xcomp contribute,appears
R291 T578 T577 punct ",",contribute
R292 T579 T575 prep in,appears
R293 T580 T579 pobj part,in
R294 T581 T575 punct ",",appears
R295 T582 T583 aux to,resistance
R296 T583 T568 advcl resistance,mutated
R297 T584 T585 aux to,temozolomide
R298 T585 T583 advcl temozolomide,resistance
R299 T586 T587 punct (,TMZ
R300 T587 T585 appos TMZ,temozolomide
R301 T588 T587 punct ),TMZ
R302 T589 T585 cc and,temozolomide
R303 T590 T591 amod therapeutic,drugs
R304 T591 T585 conj drugs,temozolomide
R305 T592 T568 punct .,mutated
R306 T593 T596 compound WW,WWOX
R307 T594 T596 compound domain-containing,WWOX
R308 T595 T596 compound oxidoreductase,WWOX
R309 T596 T602 nsubj WWOX,is
R310 T597 T598 punct (,FOR
R311 T598 T596 prep FOR,WWOX
R312 T599 T598 cc or,FOR
R313 T600 T598 conj WOX1,FOR
R314 T601 T598 punct ),FOR
R315 T602 T602 ROOT is,is
R316 T603 T605 det a,protein
R317 T604 T605 amod proapoptotic,protein
R318 T605 T602 attr protein,is
R319 T606 T602 cc and,is
R320 T607 T608 auxpass is,considered
R321 T608 T602 conj considered,is
R322 T609 T608 prep as,considered
R323 T610 T612 det a,suppressor
R324 T611 T612 compound tumor,suppressor
R325 T612 T609 pobj suppressor,as
R326 T613 T602 punct .,is
R327 T614 T621 nsubjpass Loss,seen
R328 T615 T614 prep of,Loss
R329 T616 T618 compound WWOX,expression
R330 T618 T615 pobj expression,of
R331 T619 T621 auxpass is,seen
R332 T620 T621 advmod frequently,seen
R333 T621 T621 ROOT seen,seen
R334 T622 T621 prep in,seen
R335 T623 T625 amod malignant,cells
R336 T624 T625 compound cancer,cells
R337 T625 T622 pobj cells,in
R338 T626 T621 prep due,seen
R339 T627 T628 aux to,promoter
R340 T628 T626 xcomp promoter,due
R341 T629 T626 conj hypermethylation,due
R342 T630 T629 punct ",",hypermethylation
R343 T631 T632 amod genetic,alterations
R344 T632 T629 conj alterations,hypermethylation
R345 T633 T632 punct ",",alterations
R346 T634 T632 cc and,alterations
R347 T635 T636 amod translational,blockade
R348 T636 T632 conj blockade,alterations
R349 T637 T621 punct .,seen
R350 T638 T647 advmod Intriguingly,induces
R351 T639 T641 punct ",",expression
R352 T640 T641 amod ectopic,expression
R353 T641 T647 nsubj expression,induces
R354 T642 T641 prep of,expression
R355 T643 T644 amod wild,type
R356 T644 T645 compound type,WWOX
R357 T645 T642 pobj WWOX,of
R358 T646 T647 advmod preferentially,induces
R359 T647 T647 ROOT induces,induces
R360 T648 T647 dobj apoptosis,induces
R361 T649 T648 prep in,apoptosis
R362 T650 T652 amod human,cells
R363 T651 T652 compound glioblastoma,cells
R364 T652 T649 pobj cells,in
R365 T653 T648 acl harboring,apoptosis
R366 T654 T655 amod mutant,p53
R367 T655 T653 dobj p53,harboring
R368 T656 T647 punct .,induces
R369 T657 T659 nsubjpass WWOX,known
R370 T658 T659 auxpass is,known
R371 T659 T659 ROOT known,known
R372 T660 T662 aux to,bind
R373 T661 T662 advmod physically,bind
R374 T662 T659 xcomp bind,known
R375 T663 T659 cc and,known
R376 T664 T659 conj stabilize,known
R377 T665 T666 amod wild,type
R378 T666 T667 compound type,p53
R379 T667 T664 dobj p53,stabilize
R380 T668 T659 punct .,known
R381 T669 T672 advmod Here,provide
R382 T670 T672 punct ",",provide
R383 T671 T672 nsubj we,provide
R384 T672 T672 ROOT provide,provide
R385 T673 T674 det an,overview
R386 T674 T672 dobj overview,provide
R387 T675 T674 prep for,overview
R388 T676 T678 det the,knowledge
R389 T677 T678 amod updated,knowledge
R390 T678 T675 pobj knowledge,for
R391 T679 T678 prep in,knowledge
R392 T680 T679 pobj p53,in
R393 T681 T680 cc and,p53
R394 T682 T680 conj WWOX,p53
R396 T684 T672 cc and,provide
R397 T685 T672 conj postulate,provide
R398 T686 T687 amod potential,scenarios
R399 T687 T685 dobj scenarios,postulate
R400 T688 T698 nsubj that,modulate
R401 T689 T690 amod wild,type
R402 T690 T698 nsubj type,modulate
R403 T691 T690 cc and,type
R404 T692 T693 amod mutant,p53
R405 T693 T690 conj p53,type
R406 T694 T693 punct ",",p53
R407 T695 T693 cc or,p53
R408 T696 T693 conj isoforms,p53
R409 T697 T698 punct ",",modulate
R410 T698 T687 relcl modulate,scenarios
R411 T699 T701 det the,function
R412 T700 T701 amod apoptotic,function
R413 T701 T698 dobj function,modulate
R414 T702 T701 prep of,function
R415 T703 T702 pobj WWOX,of
R416 T704 T672 punct .,provide
R417 T705 T706 nsubj We,propose
R418 T706 T706 ROOT propose,propose
R419 T707 T719 mark that,needed
R420 T708 T719 csubj triggering,needed
R421 T709 T710 compound WWOX,activation
R422 T710 T708 dobj activation,triggering
R423 T711 T710 prep by,activation
R424 T712 T713 amod therapeutic,drugs
R425 T713 T711 pobj drugs,by
R426 T715 T717 amod p53,deficiency
R427 T716 T717 amod functional,deficiency
R428 T717 T714 pobj deficiency,under
R429 T718 T719 auxpass is,needed
R430 T719 T706 ccomp needed,propose
R431 T720 T721 aux to,overcome
R432 T721 T719 advcl overcome,needed
R433 T722 T723 compound TMZ,resistance
R434 T723 T721 dobj resistance,overcome
R435 T724 T721 cc and,overcome
R436 T725 T721 conj induce,overcome
R437 T726 T728 compound GBM,death
R438 T727 T728 compound cell,death
R439 T728 T725 dobj death,induce
R440 T729 T706 punct .,propose
R442 T617 T618 compound gene,expression
R443 T714 T710 prep under,activation

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T551 576-636 Binding denotes WWOX is known to physically bind and stabilize wild type p53
T550 290-313 Gene_expression denotes of WWOX gene expression
T549 456-492 Gene_expression denotes ectopic expression of wild type WWOX
T548 856-871 Positive_regulation denotes WWOX activation
T547 576-636 Regulation denotes WWOX is known to physically bind and stabilize wild type p53
T545 856-860 Protein denotes WWOX
T544 947-950 Entity denotes TMZ
T543 475-492 Protein denotes of wild type WWOX
T542 875-892 Entity denotes therapeutic drugs
T541 221-243 Protein denotes a proapoptotic protein
T540 529-574 Entity denotes human glioblastoma cells harboring mutant p53
T539 293-297 Protein denotes WWOX
T538 696-699 Protein denotes p53
T537 163-198 Protein denotes WW domain-containing oxidoreductase
T536 899-902 Protein denotes p53
T535 121-139 Entity denotes temozolomide (TMZ)
T534 212-216 Protein denotes WOX1
T533 366-374 Entity denotes promoter
T532 163-203 Protein denotes WW domain-containing oxidoreductase WWOX
T531 265-283 Protein denotes a tumor suppressor
T530 820-827 Protein denotes of WWOX
T528 763-787 Protein denotes mutant p53, or isoforms,
T527 564-574 Protein denotes mutant p53
T526 144-161 Entity denotes therapeutic drugs
T525 0-20 Protein denotes Tumor suppressor p53
T524 576-580 Protein denotes WWOX
T523 135-138 Entity denotes TMZ
T522 704-708 Protein denotes WWOX
T521 336-358 Entity denotes malignant cancer cells
T520 623-636 Protein denotes wild type p53
R259 T520 T547 themeOf wild type p53,WWOX is known to physically bind and stabilize wild type p53
R260 T524 T547 causeOf WWOX,WWOX is known to physically bind and stabilize wild type p53
R261 T524 T551 themeOf WWOX,WWOX is known to physically bind and stabilize wild type p53
R262 T539 T550 themeOf WWOX,of WWOX gene expression
R263 T543 T549 themeOf of wild type WWOX,ectopic expression of wild type WWOX
R264 T545 T548 themeOf WWOX,WWOX activation

DLUT931

Id Subject Object Predicate Lexical cue
T424 845-855 Positive_regulation denotes triggering
T423 914-924 Negative_regulation denotes deficiency
T422 861-871 Positive_regulation denotes activation
T421 788-796 Regulation denotes modulate
T420 604-608 Binding denotes bind
T419 508-515 Positive_regulation denotes induces
T418 464-474 Gene_expression denotes expression
T417 285-289 Negative_regulation denotes Loss
T416 303-313 Gene_expression denotes expression
T414 899-902 Protein denotes p53
T413 856-860 Protein denotes WWOX
T412 823-827 Protein denotes WWOX
T411 770-773 Protein denotes p53
T410 704-708 Protein denotes WWOX
T409 696-699 Protein denotes p53
T408 633-636 Protein denotes p53
T407 576-580 Protein denotes WWOX
T406 488-492 Protein denotes WWOX
T405 571-574 Protein denotes p53
T404 293-297 Protein denotes WWOX
T403 212-216 Protein denotes WOX1
T402 205-208 Protein denotes FOR
T401 199-203 Protein denotes WWOX
T400 163-198 Protein denotes WW domain-containing oxidoreductase
T399 17-20 Protein denotes p53
R214 T404 T416 themeOf WWOX,expression
R215 T406 T418 themeOf WWOX,expression
R216 T407 T420 themeOf WWOX,bind
R217 T408 T420 themeOf p53,bind
R218 T411 T421 causeOf p53,modulate
R219 T412 T421 themeOf WWOX,modulate
R220 T413 T422 themeOf WWOX,activation
R221 T414 T423 themeOf p53,deficiency
R222 T416 T417 themeOf expression,Loss
R223 T418 T419 themeOf expression,induces
R224 T422 T424 themeOf activation,triggering
R225 T423 T424 causeOf deficiency,triggering

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T473 861-871 Positive_regulation denotes activation
T472 845-855 Positive_regulation denotes triggering
T471 914-924 Negative_regulation denotes deficiency
T470 604-608 Binding denotes bind
T469 464-474 Gene_expression denotes expression
T468 508-515 Positive_regulation denotes induces
T467 285-289 Negative_regulation denotes Loss
T466 303-313 Gene_expression denotes expression
T464 899-902 Protein denotes p53
T463 856-860 Protein denotes WWOX
T462 823-827 Protein denotes WWOX
T461 770-773 Protein denotes p53
T460 704-708 Protein denotes WWOX
T459 696-699 Protein denotes p53
T458 633-636 Protein denotes p53
T457 576-580 Protein denotes WWOX
T456 488-492 Protein denotes WWOX
T455 571-574 Protein denotes p53
T454 293-297 Protein denotes WWOX
T453 212-216 Protein denotes WOX1
T452 205-208 Protein denotes FOR
T451 199-203 Protein denotes WWOX
T450 163-198 Protein denotes WW domain-containing oxidoreductase
T449 17-20 Protein denotes p53
R231 T454 T466 themeOf WWOX,expression
R232 T456 T469 themeOf WWOX,expression
R233 T457 T470 themeOf WWOX,bind
R234 T463 T473 themeOf WWOX,activation
R235 T464 T471 themeOf p53,deficiency
R236 T466 T467 themeOf expression,Loss
R237 T469 T468 themeOf expression,induces
R238 T473 T472 themeOf activation,triggering

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T380 845-855 Positive_regulation denotes triggering
T379 861-871 Positive_regulation denotes activation
T378 914-924 Negative_regulation denotes deficiency
T377 604-608 Binding denotes bind
T376 613-622 Positive_regulation denotes stabilize
T375 464-474 Gene_expression denotes expression
T374 303-313 Gene_expression denotes expression
T373 285-289 Negative_regulation denotes Loss
T372 899-902 Protein denotes p53
T371 856-860 Protein denotes WWOX
T370 823-827 Protein denotes WWOX
T369 770-773 Protein denotes p53
T368 704-708 Protein denotes WWOX
T367 696-699 Protein denotes p53
T366 633-636 Protein denotes p53
T365 576-580 Protein denotes WWOX
T364 488-492 Protein denotes WWOX
T363 571-574 Protein denotes p53
T362 293-297 Protein denotes WWOX
T361 212-216 Protein denotes WOX1
T360 205-208 Protein denotes FOR
T359 199-203 Protein denotes WWOX
T358 163-198 Protein denotes WW domain-containing oxidoreductase
T357 17-20 Protein denotes p53
R204 T362 T374 themeOf WWOX,expression
R205 T364 T375 themeOf WWOX,expression
R206 T365 T377 themeOf WWOX,bind
R207 T366 T376 themeOf p53,stabilize
R208 T371 T379 themeOf WWOX,activation
R209 T372 T378 themeOf p53,deficiency
R210 T374 T373 themeOf expression,Loss
R211 T379 T380 themeOf activation,triggering

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T396 0-20 http://www.uniprot.org/uniprot/P04637 denotes Tumor suppressor p53
T395 770-773 http://www.uniprot.org/uniprot/P04637 denotes p53
T394 696-699 http://www.uniprot.org/uniprot/P04637 denotes p53
T393 633-636 http://www.uniprot.org/uniprot/P04637 denotes p53
T392 571-574 http://www.uniprot.org/uniprot/P04637 denotes p53
T391 17-20 http://www.uniprot.org/uniprot/P04637 denotes p53
T389 212-216 http://www.uniprot.org/uniprot/Q9NZC7 denotes WOX1
T388 205-208 http://www.uniprot.org/uniprot/Q9NZC7 denotes FOR
T387 823-827 http://www.uniprot.org/uniprot/Q9NZC7 denotes WWOX
T386 704-708 http://www.uniprot.org/uniprot/Q9NZC7 denotes WWOX
T382 199-203 http://www.uniprot.org/uniprot/Q9NZC7 denotes WWOX
T383 293-297 http://www.uniprot.org/uniprot/Q9NZC7 denotes WWOX
T384 488-492 http://www.uniprot.org/uniprot/Q9NZC7 denotes WWOX
T385 576-580 http://www.uniprot.org/uniprot/Q9NZC7 denotes WWOX

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T120 17-20 Protein denotes p53
T121 163-198 Protein denotes WW domain-containing oxidoreductase
T122 199-203 Protein denotes WWOX
T123 205-208 Protein denotes FOR
T124 212-216 Protein denotes WOX1
T125 293-297 Protein denotes WWOX
T126 488-492 Protein denotes WWOX
T127 571-574 Protein denotes p53
T128 576-580 Protein denotes WWOX
T129 633-636 Protein denotes p53
T130 696-699 Protein denotes p53
T131 704-708 Protein denotes WWOX
T132 770-773 Protein denotes p53
T133 823-827 Protein denotes WWOX
T134 856-860 Protein denotes WWOX
T135 899-902 Protein denotes p53

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T336 982-987 NN denotes death
T335 977-981 NN denotes cell
T334 973-976 NN denotes GBM
T333 966-972 VB denotes induce
T332 962-965 CC denotes and
T331 951-961 NN denotes resistance
T330 947-950 NN denotes TMZ
T329 938-946 VB denotes overcome
T328 935-937 TO denotes to
T327 928-934 VB denotes needed
T326 925-927 VB denotes is
T325 914-924 NN denotes deficiency
T324 903-913 JJ denotes functional
T323 899-902 NN denotes p53
T322 893-898 IN denotes under
T321 887-892 NN denotes drugs
T320 875-886 JJ denotes therapeutic
T319 872-874 IN denotes by
T318 861-871 NN denotes activation
T317 856-860 NN denotes WWOX
T316 845-855 VB denotes triggering
T315 840-844 IN denotes that
T314 832-839 VB denotes propose
T313 829-831 PRP denotes We
T312 823-827 NN denotes WWOX
T311 820-822 IN denotes of
T310 811-819 NN denotes function
T309 801-810 JJ denotes apoptotic
T308 797-800 DT denotes the
T307 788-796 VB denotes modulate
T306 786-787 -COMMA- denotes ,
T305 778-786 NN denotes isoforms
T304 775-777 CC denotes or
T303 773-774 -COMMA- denotes ,
T302 770-773 NN denotes p53
T301 763-769 JJ denotes mutant
T300 759-762 CC denotes and
T299 754-758 NN denotes type
T298 749-753 JJ denotes wild
T297 744-748 IN denotes that
T296 734-743 NN denotes scenarios
T295 724-733 JJ denotes potential
T294 714-723 VB denotes postulate
T293 710-713 CC denotes and
T292 708-709 -COMMA- denotes ,
T291 704-708 NN denotes WWOX
T290 700-703 CC denotes and
T289 696-699 NN denotes p53
T288 693-695 IN denotes in
T287 683-692 NN denotes knowledge
T286 675-682 VB denotes updated
T285 671-674 DT denotes the
T284 667-670 IN denotes for
T283 658-666 NN denotes overview
T282 655-657 DT denotes an
T281 647-654 VB denotes provide
T280 644-646 PRP denotes we
T279 642-643 -COMMA- denotes ,
T278 638-642 RB denotes Here
T277 633-636 NN denotes p53
T276 628-632 NN denotes type
T275 623-627 JJ denotes wild
T274 613-622 VB denotes stabilize
T273 609-612 CC denotes and
T272 604-608 VB denotes bind
T271 593-603 RB denotes physically
T270 590-592 TO denotes to
T269 584-589 VB denotes known
T268 581-583 VB denotes is
T267 576-580 NN denotes WWOX
T266 571-574 NN denotes p53
T265 564-570 JJ denotes mutant
T264 554-563 VB denotes harboring
T263 548-553 NN denotes cells
T262 535-547 NN denotes glioblastoma
T261 529-534 JJ denotes human
T260 526-528 IN denotes in
T259 516-525 NN denotes apoptosis
T258 508-515 VB denotes induces
T257 493-507 RB denotes preferentially
T256 488-492 NN denotes WWOX
T255 483-487 NN denotes type
T254 478-482 JJ denotes wild
T253 475-477 IN denotes of
T252 464-474 NN denotes expression
T251 456-463 JJ denotes ectopic
T250 454-455 -COMMA- denotes ,
T249 442-454 RB denotes Intriguingly
T248 432-440 NN denotes blockade
T247 418-431 JJ denotes translational
T246 414-417 CC denotes and
T245 412-413 -COMMA- denotes ,
T244 401-412 NN denotes alterations
T243 393-400 JJ denotes genetic
T242 391-392 -COMMA- denotes ,
T241 375-391 NN denotes hypermethylation
T240 366-374 NN denotes promoter
T239 363-365 TO denotes to
T238 359-362 JJ denotes due
T237 353-358 NN denotes cells
T236 346-352 NN denotes cancer
T235 336-345 JJ denotes malignant
T234 333-335 IN denotes in
T233 328-332 VB denotes seen
T232 317-327 RB denotes frequently
T231 314-316 VB denotes is
T230 303-313 NN denotes expression
T229 298-302 NN denotes gene
T228 293-297 NN denotes WWOX
T227 290-292 IN denotes of
T226 285-289 NN denotes Loss
T225 273-283 NN denotes suppressor
T224 267-272 NN denotes tumor
T223 265-266 DT denotes a
T222 262-264 IN denotes as
T221 251-261 VB denotes considered
T220 248-250 VB denotes is
T219 244-247 CC denotes and
T218 236-243 NN denotes protein
T217 223-235 JJ denotes proapoptotic
T216 221-222 DT denotes a
T215 218-220 VB denotes is
T214 216-217 -RRB- denotes )
T213 212-216 NN denotes WOX1
T212 209-211 CC denotes or
T211 205-208 NN denotes FOR
T210 204-205 -LRB- denotes (
T209 199-203 NN denotes WWOX
T208 184-198 NN denotes oxidoreductase
T207 166-183 JJ denotes domain-containing
T206 163-165 JJ denotes WW
T205 156-161 NN denotes drugs
T204 144-155 JJ denotes therapeutic
T203 140-143 CC denotes and
T202 138-139 -RRB- denotes )
T201 135-138 NN denotes TMZ
T200 134-135 -LRB- denotes (
T199 121-133 NN denotes temozolomide
T198 118-120 TO denotes to
T197 107-117 NN denotes resistance
T196 104-106 TO denotes to
T195 102-103 -COMMA- denotes ,
T194 98-102 NN denotes part
T193 95-97 IN denotes in
T192 93-94 -COMMA- denotes ,
T191 83-93 VB denotes contribute
T190 80-82 TO denotes to
T189 72-79 VB denotes appears
T188 68-71 CC denotes and
T187 66-67 -RRB- denotes )
T186 62-66 NN denotes GBMs
T185 61-62 -LRB- denotes (
T184 47-60 NN denotes glioblastomas
T183 44-46 IN denotes in
T182 36-43 VB denotes mutated
T181 25-35 RB denotes frequently
T180 21-24 VB denotes are
T179 17-20 NN denotes p53
T178 6-16 NN denotes suppressor
T177 0-5 NN denotes Tumor
R152 T287 T286 arg2Of knowledge,updated
R38 T179 T177 arg1Of p53,Tumor
R39 T179 T178 arg1Of p53,suppressor
R40 T179 T180 arg1Of p53,are
R41 T179 T182 arg2Of p53,mutated
R42 T179 T189 arg1Of p53,appears
R43 T179 T191 arg1Of p53,contribute
R44 T182 T180 arg2Of mutated,are
R45 T182 T181 arg1Of mutated,frequently
R46 T182 T183 arg1Of mutated,in
R47 T182 T188 arg1Of mutated,and
R48 T184 T183 arg2Of glioblastomas,in
R49 T184 T185 arg1Of glioblastomas,(
R50 T186 T185 arg2Of GBMs,(
R51 T187 T185 arg3Of ),(
R52 T189 T188 arg2Of appears,and
R53 T191 T189 arg2Of contribute,appears
R54 T191 T190 arg1Of contribute,to
R55 T191 T192 arg1Of contribute,","
R56 T191 T193 arg1Of contribute,in
R57 T191 T195 arg1Of contribute,","
R58 T191 T196 arg1Of contribute,to
R59 T194 T193 arg2Of part,in
R60 T197 T198 arg1Of resistance,to
R61 T197 T203 arg1Of resistance,and
R62 T199 T198 arg2Of temozolomide,to
R63 T199 T200 arg1Of temozolomide,(
R64 T201 T200 arg2Of TMZ,(
R65 T202 T200 arg3Of ),(
R66 T203 T196 arg2Of and,to
R67 T205 T203 arg2Of drugs,and
R68 T205 T204 arg1Of drugs,therapeutic
R69 T209 T206 arg1Of WWOX,WW
R70 T209 T207 arg1Of WWOX,domain-containing
R71 T209 T208 arg1Of WWOX,oxidoreductase
R72 T209 T210 arg1Of WWOX,(
R73 T209 T215 arg1Of WWOX,is
R74 T209 T220 arg1Of WWOX,is
R75 T209 T221 arg2Of WWOX,considered
R76 T211 T212 arg1Of FOR,or
R77 T212 T210 arg2Of or,(
R78 T213 T212 arg2Of WOX1,or
R79 T214 T210 arg3Of ),(
R80 T215 T219 arg1Of is,and
R81 T218 T215 arg2Of protein,is
R82 T218 T216 arg1Of protein,a
R83 T218 T217 arg1Of protein,proapoptotic
R84 T221 T219 arg2Of considered,and
R85 T221 T220 arg2Of considered,is
R86 T221 T222 arg1Of considered,as
R87 T225 T222 arg2Of suppressor,as
R88 T225 T223 arg1Of suppressor,a
R89 T225 T224 arg1Of suppressor,tumor
R90 T226 T227 arg1Of Loss,of
R91 T226 T231 arg1Of Loss,is
R92 T226 T233 arg2Of Loss,seen
R93 T230 T227 arg2Of expression,of
R94 T230 T228 arg1Of expression,WWOX
R95 T230 T229 arg1Of expression,gene
R96 T233 T231 arg2Of seen,is
R97 T233 T232 arg1Of seen,frequently
R98 T233 T234 arg1Of seen,in
R99 T233 T239 arg1Of seen,to
R100 T237 T234 arg2Of cells,in
R101 T237 T235 arg1Of cells,malignant
R102 T237 T236 arg1Of cells,cancer
R103 T237 T238 arg1Of cells,due
R104 T241 T240 arg1Of hypermethylation,promoter
R105 T241 T242 arg1Of hypermethylation,","
R106 T242 T246 arg1Of ",",and
R107 T244 T242 arg2Of alterations,","
R108 T244 T243 arg1Of alterations,genetic
R109 T246 T239 arg2Of and,to
R110 T246 T245 arg1Of and,","
R111 T248 T246 arg2Of blockade,and
R112 T248 T247 arg1Of blockade,translational
R113 T252 T251 arg1Of expression,ectopic
R114 T252 T253 arg1Of expression,of
R115 T252 T258 arg1Of expression,induces
R116 T256 T253 arg2Of WWOX,of
R117 T256 T254 arg1Of WWOX,wild
R118 T256 T255 arg1Of WWOX,type
R119 T258 T249 arg1Of induces,Intriguingly
R120 T258 T250 arg1Of induces,","
R121 T258 T257 arg1Of induces,preferentially
R122 T258 T260 arg1Of induces,in
R123 T259 T258 arg2Of apoptosis,induces
R124 T263 T260 arg2Of cells,in
R125 T263 T261 arg1Of cells,human
R126 T263 T262 arg1Of cells,glioblastoma
R127 T263 T264 arg1Of cells,harboring
R128 T266 T264 arg2Of p53,harboring
R129 T266 T265 arg1Of p53,mutant
R130 T267 T268 arg1Of WWOX,is
R131 T267 T269 arg2Of WWOX,known
R132 T267 T272 arg1Of WWOX,bind
R133 T267 T274 arg1Of WWOX,stabilize
R134 T269 T268 arg2Of known,is
R135 T272 T273 arg1Of bind,and
R136 T273 T269 arg3Of and,known
R137 T273 T270 arg1Of and,to
R138 T273 T271 arg1Of and,physically
R139 T274 T273 arg2Of stabilize,and
R140 T277 T272 arg2Of p53,bind
R141 T277 T274 arg2Of p53,stabilize
R142 T277 T275 arg1Of p53,wild
R143 T277 T276 arg1Of p53,type
R144 T280 T281 arg1Of we,provide
R145 T280 T294 arg1Of we,postulate
R146 T281 T293 arg1Of provide,and
R147 T283 T281 arg2Of overview,provide
R148 T283 T282 arg1Of overview,an
R149 T283 T284 arg1Of overview,for
R150 T287 T284 arg2Of knowledge,for
R151 T287 T285 arg1Of knowledge,the
R153 T287 T288 arg1Of knowledge,in
R154 T289 T290 arg1Of p53,and
R155 T290 T288 arg2Of and,in
R156 T291 T290 arg2Of WWOX,and
R157 T293 T278 arg1Of and,Here
R158 T293 T279 arg1Of and,","
R159 T293 T292 arg1Of and,","
R160 T294 T293 arg2Of postulate,and
R161 T296 T294 arg2Of scenarios,postulate
R162 T296 T295 arg1Of scenarios,potential
R163 T296 T297 arg1Of scenarios,that
R164 T299 T298 arg1Of type,wild
R165 T299 T300 arg1Of type,and
R166 T300 T304 arg1Of and,or
R167 T302 T300 arg2Of p53,and
R168 T302 T301 arg1Of p53,mutant
R169 T304 T303 arg1Of or,","
R170 T304 T307 arg1Of or,modulate
R171 T305 T304 arg2Of isoforms,or
R172 T307 T297 arg2Of modulate,that
R173 T307 T306 arg1Of modulate,","
R174 T310 T307 arg2Of function,modulate
R175 T310 T308 arg1Of function,the
R176 T310 T309 arg1Of function,apoptotic
R177 T310 T311 arg1Of function,of
R178 T312 T311 arg2Of WWOX,of
R179 T313 T314 arg1Of We,propose
R180 T318 T316 arg1Of activation,triggering
R181 T318 T317 arg1Of activation,WWOX
R182 T318 T319 arg1Of activation,by
R183 T318 T322 arg1Of activation,under
R184 T318 T326 arg1Of activation,is
R185 T318 T327 arg2Of activation,needed
R186 T321 T319 arg2Of drugs,by
R187 T321 T320 arg1Of drugs,therapeutic
R188 T325 T322 arg2Of deficiency,under
R189 T325 T323 arg1Of deficiency,p53
R190 T325 T324 arg1Of deficiency,functional
R191 T327 T314 arg2Of needed,propose
R192 T327 T315 arg1Of needed,that
R193 T327 T326 arg2Of needed,is
R194 T327 T328 modOf needed,to
R195 T329 T332 arg1Of overcome,and
R196 T331 T329 arg2Of resistance,overcome
R197 T331 T330 arg1Of resistance,TMZ
R198 T332 T328 arg1Of and,to
R199 T333 T332 arg2Of induce,and
R200 T336 T333 arg2Of death,induce
R201 T336 T334 arg1Of death,GBM
R202 T336 T335 arg1Of death,cell

GO-BP

Id Subject Object Predicate Lexical cue
T144 982-987 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T143 977-987 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T142 516-525 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T141 516-525 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T140 298-313 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T138 267-283 http://purl.obolibrary.org/obo/GO_0051726 denotes tumor suppressor
T137 0-16 http://purl.obolibrary.org/obo/GO_0051726 denotes Tumor suppressor

GO-CC

Id Subject Object Predicate Lexical cue
T147 977-981 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T146 548-553 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T145 353-358 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T82 285-441 Sentence denotes Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade.
T81 163-284 Sentence denotes WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor.
T80 0-162 Sentence denotes Tumor suppressor p53 are frequently mutated in glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs.
T86 829-988 Sentence denotes We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.
T85 638-828 Sentence denotes Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild type and mutant p53, or isoforms, modulate the apoptotic function of WWOX.
T84 576-637 Sentence denotes WWOX is known to physically bind and stabilize wild type p53.
T83 442-575 Sentence denotes Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53.
T3 0-162 Sentence denotes Tumor suppressor p53 are frequently mutated in glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs.
T4 163-284 Sentence denotes WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor.
T5 285-441 Sentence denotes Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade.
T6 442-575 Sentence denotes Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53.
T7 576-637 Sentence denotes WWOX is known to physically bind and stabilize wild type p53.
T8 638-828 Sentence denotes Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild type and mutant p53, or isoforms, modulate the apoptotic function of WWOX.
T9 829-988 Sentence denotes We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.

simple1

Id Subject Object Predicate Lexical cue
T165 899-902 Protein denotes p53
T164 856-860 Protein denotes WWOX
T163 823-827 Protein denotes WWOX
T162 770-773 Protein denotes p53
T161 704-708 Protein denotes WWOX
T160 696-699 Protein denotes p53
T159 633-636 Protein denotes p53
T158 576-580 Protein denotes WWOX
T157 571-574 Protein denotes p53
T156 488-492 Protein denotes WWOX
T155 293-297 Protein denotes WWOX
T154 212-216 Protein denotes WOX1
T153 205-208 Protein denotes FOR
T152 199-203 Protein denotes WWOX
T151 163-198 Protein denotes WW domain-containing oxidoreductase
T150 17-20 Protein denotes p53