PMC:3586680 / 854-1143 JSONTXT

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    test3

    {"project":"test3","denotations":[{"id":"T78","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T77","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T76","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T75","span":{"begin":5,"end":8},"obj":"Protein"},{"id":"T58","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T57","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T56","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T55","span":{"begin":5,"end":8},"obj":"Protein"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    testone

    {"project":"testone","denotations":[{"id":"T36","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T35","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T34","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T33","span":{"begin":5,"end":8},"obj":"Protein"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    bionlp-st-ge-2016-test-tees

    {"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T496","span":{"begin":149,"end":159},"obj":"Negative_regulation"},{"id":"T495","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T494","span":{"begin":23,"end":31},"obj":"Regulation"},{"id":"T493","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T492","span":{"begin":5,"end":8},"obj":"Protein"}],"relations":[{"id":"R246","pred":"causeOf","subj":"T492","obj":"T494"},{"id":"R247","pred":"themeOf","subj":"T493","obj":"T494"},{"id":"R248","pred":"themeOf","subj":"T495","obj":"T496"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    bionlp-st-ge-2016-spacy-parsed

    {"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T729","span":{"begin":222,"end":223},"obj":"."},{"id":"T728","span":{"begin":217,"end":222},"obj":"NN"},{"id":"T727","span":{"begin":212,"end":216},"obj":"NN"},{"id":"T726","span":{"begin":208,"end":211},"obj":"NNP"},{"id":"T725","span":{"begin":201,"end":207},"obj":"VB"},{"id":"T724","span":{"begin":197,"end":200},"obj":"CC"},{"id":"T723","span":{"begin":186,"end":196},"obj":"NN"},{"id":"T722","span":{"begin":182,"end":185},"obj":"NNP"},{"id":"T721","span":{"begin":173,"end":181},"obj":"VB"},{"id":"T720","span":{"begin":170,"end":172},"obj":"TO"},{"id":"T719","span":{"begin":163,"end":169},"obj":"VBN"},{"id":"T718","span":{"begin":160,"end":162},"obj":"VBZ"},{"id":"T717","span":{"begin":149,"end":159},"obj":"NN"},{"id":"T716","span":{"begin":138,"end":148},"obj":"JJ"},{"id":"T715","span":{"begin":134,"end":137},"obj":"NN"},{"id":"T713","span":{"begin":122,"end":127},"obj":"NNS"},{"id":"T712","span":{"begin":110,"end":121},"obj":"JJ"},{"id":"T711","span":{"begin":107,"end":109},"obj":"IN"},{"id":"T710","span":{"begin":96,"end":106},"obj":"NN"},{"id":"T709","span":{"begin":91,"end":95},"obj":"NNP"},{"id":"T708","span":{"begin":80,"end":90},"obj":"VBG"},{"id":"T707","span":{"begin":75,"end":79},"obj":"IN"},{"id":"T706","span":{"begin":67,"end":74},"obj":"VBP"},{"id":"T705","span":{"begin":64,"end":66},"obj":"PRP"},{"id":"T704","span":{"begin":62,"end":63},"obj":"."},{"id":"T703","span":{"begin":58,"end":62},"obj":"NNP"},{"id":"T702","span":{"begin":55,"end":57},"obj":"IN"},{"id":"T701","span":{"begin":46,"end":54},"obj":"NN"},{"id":"T700","span":{"begin":36,"end":45},"obj":"JJ"},{"id":"T699","span":{"begin":32,"end":35},"obj":"DT"},{"id":"T698","span":{"begin":23,"end":31},"obj":"VBP"},{"id":"T697","span":{"begin":21,"end":22},"obj":","},{"id":"T696","span":{"begin":13,"end":21},"obj":"NNS"},{"id":"T695","span":{"begin":10,"end":12},"obj":"CC"},{"id":"T694","span":{"begin":8,"end":9},"obj":","},{"id":"T693","span":{"begin":5,"end":8},"obj":"NN"},{"id":"T714","span":{"begin":128,"end":133},"obj":"IN"}],"relations":[{"id":"R406","pred":"punct","subj":"T694","obj":"T693"},{"id":"R407","pred":"cc","subj":"T695","obj":"T693"},{"id":"R408","pred":"conj","subj":"T696","obj":"T693"},{"id":"R409","pred":"punct","subj":"T697","obj":"T698"},{"id":"R411","pred":"det","subj":"T699","obj":"T701"},{"id":"R412","pred":"amod","subj":"T700","obj":"T701"},{"id":"R413","pred":"dobj","subj":"T701","obj":"T698"},{"id":"R414","pred":"prep","subj":"T702","obj":"T701"},{"id":"R415","pred":"pobj","subj":"T703","obj":"T702"},{"id":"R417","pred":"nsubj","subj":"T705","obj":"T706"},{"id":"R418","pred":"ROOT","subj":"T706","obj":"T706"},{"id":"R419","pred":"mark","subj":"T707","obj":"T719"},{"id":"R420","pred":"csubj","subj":"T708","obj":"T719"},{"id":"R421","pred":"compound","subj":"T709","obj":"T710"},{"id":"R422","pred":"dobj","subj":"T710","obj":"T708"},{"id":"R423","pred":"prep","subj":"T711","obj":"T710"},{"id":"R424","pred":"amod","subj":"T712","obj":"T713"},{"id":"R425","pred":"pobj","subj":"T713","obj":"T711"},{"id":"R426","pred":"amod","subj":"T715","obj":"T717"},{"id":"R427","pred":"amod","subj":"T716","obj":"T717"},{"id":"R428","pred":"pobj","subj":"T717","obj":"T714"},{"id":"R429","pred":"auxpass","subj":"T718","obj":"T719"},{"id":"R430","pred":"ccomp","subj":"T719","obj":"T706"},{"id":"R431","pred":"aux","subj":"T720","obj":"T721"},{"id":"R432","pred":"advcl","subj":"T721","obj":"T719"},{"id":"R433","pred":"compound","subj":"T722","obj":"T723"},{"id":"R434","pred":"dobj","subj":"T723","obj":"T721"},{"id":"R435","pred":"cc","subj":"T724","obj":"T721"},{"id":"R436","pred":"conj","subj":"T725","obj":"T721"},{"id":"R437","pred":"compound","subj":"T726","obj":"T728"},{"id":"R438","pred":"compound","subj":"T727","obj":"T728"},{"id":"R439","pred":"dobj","subj":"T728","obj":"T725"},{"id":"R440","pred":"punct","subj":"T729","obj":"T706"},{"id":"R443","pred":"prep","subj":"T714","obj":"T710"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    bionlp-st-ge-2016-test-ihmc

    {"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T548","span":{"begin":91,"end":106},"obj":"Positive_regulation"},{"id":"T545","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T544","span":{"begin":182,"end":185},"obj":"Entity"},{"id":"T542","span":{"begin":110,"end":127},"obj":"Entity"},{"id":"T536","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T530","span":{"begin":55,"end":62},"obj":"Protein"}],"relations":[{"id":"R264","pred":"themeOf","subj":"T545","obj":"T548"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    DLUT931

    {"project":"DLUT931","denotations":[{"id":"T424","span":{"begin":80,"end":90},"obj":"Positive_regulation"},{"id":"T423","span":{"begin":149,"end":159},"obj":"Negative_regulation"},{"id":"T422","span":{"begin":96,"end":106},"obj":"Positive_regulation"},{"id":"T421","span":{"begin":23,"end":31},"obj":"Regulation"},{"id":"T414","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T413","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T412","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T411","span":{"begin":5,"end":8},"obj":"Protein"}],"relations":[{"id":"R218","pred":"causeOf","subj":"T411","obj":"T421"},{"id":"R219","pred":"themeOf","subj":"T412","obj":"T421"},{"id":"R220","pred":"themeOf","subj":"T413","obj":"T422"},{"id":"R221","pred":"themeOf","subj":"T414","obj":"T423"},{"id":"R224","pred":"themeOf","subj":"T422","obj":"T424"},{"id":"R225","pred":"causeOf","subj":"T423","obj":"T424"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T473","span":{"begin":96,"end":106},"obj":"Positive_regulation"},{"id":"T472","span":{"begin":80,"end":90},"obj":"Positive_regulation"},{"id":"T471","span":{"begin":149,"end":159},"obj":"Negative_regulation"},{"id":"T464","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T463","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T462","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T461","span":{"begin":5,"end":8},"obj":"Protein"}],"relations":[{"id":"R234","pred":"themeOf","subj":"T463","obj":"T473"},{"id":"R235","pred":"themeOf","subj":"T464","obj":"T471"},{"id":"R238","pred":"themeOf","subj":"T473","obj":"T472"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T380","span":{"begin":80,"end":90},"obj":"Positive_regulation"},{"id":"T379","span":{"begin":96,"end":106},"obj":"Positive_regulation"},{"id":"T378","span":{"begin":149,"end":159},"obj":"Negative_regulation"},{"id":"T372","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T371","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T370","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T369","span":{"begin":5,"end":8},"obj":"Protein"}],"relations":[{"id":"R208","pred":"themeOf","subj":"T371","obj":"T379"},{"id":"R209","pred":"themeOf","subj":"T372","obj":"T378"},{"id":"R211","pred":"themeOf","subj":"T379","obj":"T380"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T395","span":{"begin":5,"end":8},"obj":"http://www.uniprot.org/uniprot/P04637"},{"id":"T387","span":{"begin":58,"end":62},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T132","span":{"begin":5,"end":8},"obj":"Protein"},{"id":"T133","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T134","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T135","span":{"begin":134,"end":137},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    pmc-enju-pas

    {"project":"pmc-enju-pas","denotations":[{"id":"T336","span":{"begin":217,"end":222},"obj":"NN"},{"id":"T335","span":{"begin":212,"end":216},"obj":"NN"},{"id":"T334","span":{"begin":208,"end":211},"obj":"NN"},{"id":"T333","span":{"begin":201,"end":207},"obj":"VB"},{"id":"T332","span":{"begin":197,"end":200},"obj":"CC"},{"id":"T331","span":{"begin":186,"end":196},"obj":"NN"},{"id":"T330","span":{"begin":182,"end":185},"obj":"NN"},{"id":"T329","span":{"begin":173,"end":181},"obj":"VB"},{"id":"T328","span":{"begin":170,"end":172},"obj":"TO"},{"id":"T327","span":{"begin":163,"end":169},"obj":"VB"},{"id":"T326","span":{"begin":160,"end":162},"obj":"VB"},{"id":"T325","span":{"begin":149,"end":159},"obj":"NN"},{"id":"T324","span":{"begin":138,"end":148},"obj":"JJ"},{"id":"T323","span":{"begin":134,"end":137},"obj":"NN"},{"id":"T322","span":{"begin":128,"end":133},"obj":"IN"},{"id":"T321","span":{"begin":122,"end":127},"obj":"NN"},{"id":"T320","span":{"begin":110,"end":121},"obj":"JJ"},{"id":"T319","span":{"begin":107,"end":109},"obj":"IN"},{"id":"T318","span":{"begin":96,"end":106},"obj":"NN"},{"id":"T317","span":{"begin":91,"end":95},"obj":"NN"},{"id":"T316","span":{"begin":80,"end":90},"obj":"VB"},{"id":"T315","span":{"begin":75,"end":79},"obj":"IN"},{"id":"T314","span":{"begin":67,"end":74},"obj":"VB"},{"id":"T313","span":{"begin":64,"end":66},"obj":"PRP"},{"id":"T312","span":{"begin":58,"end":62},"obj":"NN"},{"id":"T311","span":{"begin":55,"end":57},"obj":"IN"},{"id":"T310","span":{"begin":46,"end":54},"obj":"NN"},{"id":"T309","span":{"begin":36,"end":45},"obj":"JJ"},{"id":"T308","span":{"begin":32,"end":35},"obj":"DT"},{"id":"T307","span":{"begin":23,"end":31},"obj":"VB"},{"id":"T306","span":{"begin":21,"end":22},"obj":"-COMMA-"},{"id":"T305","span":{"begin":13,"end":21},"obj":"NN"},{"id":"T304","span":{"begin":10,"end":12},"obj":"CC"},{"id":"T303","span":{"begin":8,"end":9},"obj":"-COMMA-"},{"id":"T302","span":{"begin":5,"end":8},"obj":"NN"}],"relations":[{"id":"R169","pred":"arg1Of","subj":"T304","obj":"T303"},{"id":"R170","pred":"arg1Of","subj":"T304","obj":"T307"},{"id":"R171","pred":"arg2Of","subj":"T305","obj":"T304"},{"id":"R173","pred":"arg1Of","subj":"T307","obj":"T306"},{"id":"R174","pred":"arg2Of","subj":"T310","obj":"T307"},{"id":"R175","pred":"arg1Of","subj":"T310","obj":"T308"},{"id":"R176","pred":"arg1Of","subj":"T310","obj":"T309"},{"id":"R177","pred":"arg1Of","subj":"T310","obj":"T311"},{"id":"R178","pred":"arg2Of","subj":"T312","obj":"T311"},{"id":"R179","pred":"arg1Of","subj":"T313","obj":"T314"},{"id":"R180","pred":"arg1Of","subj":"T318","obj":"T316"},{"id":"R181","pred":"arg1Of","subj":"T318","obj":"T317"},{"id":"R182","pred":"arg1Of","subj":"T318","obj":"T319"},{"id":"R183","pred":"arg1Of","subj":"T318","obj":"T322"},{"id":"R184","pred":"arg1Of","subj":"T318","obj":"T326"},{"id":"R185","pred":"arg2Of","subj":"T318","obj":"T327"},{"id":"R186","pred":"arg2Of","subj":"T321","obj":"T319"},{"id":"R187","pred":"arg1Of","subj":"T321","obj":"T320"},{"id":"R188","pred":"arg2Of","subj":"T325","obj":"T322"},{"id":"R189","pred":"arg1Of","subj":"T325","obj":"T323"},{"id":"R190","pred":"arg1Of","subj":"T325","obj":"T324"},{"id":"R191","pred":"arg2Of","subj":"T327","obj":"T314"},{"id":"R192","pred":"arg1Of","subj":"T327","obj":"T315"},{"id":"R193","pred":"arg2Of","subj":"T327","obj":"T326"},{"id":"R194","pred":"modOf","subj":"T327","obj":"T328"},{"id":"R195","pred":"arg1Of","subj":"T329","obj":"T332"},{"id":"R196","pred":"arg2Of","subj":"T331","obj":"T329"},{"id":"R197","pred":"arg1Of","subj":"T331","obj":"T330"},{"id":"R198","pred":"arg1Of","subj":"T332","obj":"T328"},{"id":"R199","pred":"arg2Of","subj":"T333","obj":"T332"},{"id":"R200","pred":"arg2Of","subj":"T336","obj":"T333"},{"id":"R201","pred":"arg1Of","subj":"T336","obj":"T334"},{"id":"R202","pred":"arg1Of","subj":"T336","obj":"T335"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T144","span":{"begin":217,"end":222},"obj":"http://purl.obolibrary.org/obo/GO_0016265"},{"id":"T143","span":{"begin":212,"end":222},"obj":"http://purl.obolibrary.org/obo/GO_0008219"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T147","span":{"begin":212,"end":216},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    sentences

    {"project":"sentences","denotations":[{"id":"T86","span":{"begin":64,"end":223},"obj":"Sentence"},{"id":"T9","span":{"begin":64,"end":223},"obj":"Sentence"},{"id":"T10","span":{"begin":225,"end":282},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}

    simple1

    {"project":"simple1","denotations":[{"id":"T165","span":{"begin":134,"end":137},"obj":"Protein"},{"id":"T164","span":{"begin":91,"end":95},"obj":"Protein"},{"id":"T163","span":{"begin":58,"end":62},"obj":"Protein"},{"id":"T162","span":{"begin":5,"end":8},"obj":"Protein"}],"text":"tant p53, or isoforms, modulate the apoptotic function of WWOX. We propose that triggering WWOX activation by therapeutic drugs under p53 functional deficiency is needed to overcome TMZ resistance and induce GBM cell death.\n\nMechanisms of Resistance to Temozolomide in Glioblastomas\nGliobl"}