PMC:3586680 / 562-842 JSONTXT

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    test3

    {"project":"test3","denotations":[{"id":"T74","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T73","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T72","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T71","span":{"begin":131,"end":135},"obj":"Binding"},{"id":"T70","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T69","span":{"begin":98,"end":101},"obj":"Protein"},{"id":"T68","span":{"begin":15,"end":19},"obj":"Protein"},{"id":"T54","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T53","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T52","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T51","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T50","span":{"begin":98,"end":101},"obj":"Protein"},{"id":"T49","span":{"begin":15,"end":19},"obj":"Protein"}],"relations":[{"id":"R7","pred":"themeOf","subj":"T70","obj":"T71"},{"id":"R8","pred":"themeOf","subj":"T72","obj":"T71"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    testone

    {"project":"testone","denotations":[{"id":"T40","span":{"begin":131,"end":135},"obj":"Binding"},{"id":"T32","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T31","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T30","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T29","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T28","span":{"begin":98,"end":101},"obj":"Protein"},{"id":"T27","span":{"begin":15,"end":19},"obj":"Protein"}],"relations":[{"id":"R2","pred":"themeOf","subj":"T29","obj":"T40"},{"id":"R3","pred":"themeOf","subj":"T30","obj":"T40"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    bionlp-st-ge-2016-test-tees

    {"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T491","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T490","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T489","span":{"begin":131,"end":135},"obj":"Binding"},{"id":"T488","span":{"begin":131,"end":135},"obj":"Binding"},{"id":"T487","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T486","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T484","span":{"begin":10,"end":19},"obj":"Protein"}],"relations":[{"id":"R243","pred":"themeOf","subj":"T486","obj":"T488"},{"id":"R244","pred":"themeOf","subj":"T486","obj":"T489"},{"id":"R245","pred":"themeOf","subj":"T487","obj":"T489"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    bionlp-st-ge-2016-spacy-parsed

    {"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T689","span":{"begin":276,"end":280},"obj":"JJ"},{"id":"T688","span":{"begin":271,"end":275},"obj":"WDT"},{"id":"T687","span":{"begin":261,"end":270},"obj":"NNS"},{"id":"T686","span":{"begin":251,"end":260},"obj":"JJ"},{"id":"T685","span":{"begin":241,"end":250},"obj":"VB"},{"id":"T684","span":{"begin":237,"end":240},"obj":"CC"},{"id":"T683","span":{"begin":235,"end":236},"obj":","},{"id":"T682","span":{"begin":231,"end":235},"obj":"NNP"},{"id":"T681","span":{"begin":227,"end":230},"obj":"CC"},{"id":"T680","span":{"begin":223,"end":226},"obj":"NN"},{"id":"T679","span":{"begin":220,"end":222},"obj":"IN"},{"id":"T678","span":{"begin":210,"end":219},"obj":"NN"},{"id":"T677","span":{"begin":202,"end":209},"obj":"VBN"},{"id":"T676","span":{"begin":198,"end":201},"obj":"DT"},{"id":"T675","span":{"begin":194,"end":197},"obj":"IN"},{"id":"T674","span":{"begin":185,"end":193},"obj":"NN"},{"id":"T673","span":{"begin":182,"end":184},"obj":"DT"},{"id":"T672","span":{"begin":174,"end":181},"obj":"VBP"},{"id":"T671","span":{"begin":171,"end":173},"obj":"PRP"},{"id":"T670","span":{"begin":169,"end":170},"obj":","},{"id":"T669","span":{"begin":165,"end":169},"obj":"RB"},{"id":"T668","span":{"begin":163,"end":164},"obj":"."},{"id":"T667","span":{"begin":160,"end":163},"obj":"NN"},{"id":"T666","span":{"begin":155,"end":159},"obj":"NN"},{"id":"T665","span":{"begin":150,"end":154},"obj":"JJ"},{"id":"T664","span":{"begin":140,"end":149},"obj":"VB"},{"id":"T663","span":{"begin":136,"end":139},"obj":"CC"},{"id":"T662","span":{"begin":131,"end":135},"obj":"NN"},{"id":"T661","span":{"begin":120,"end":130},"obj":"RB"},{"id":"T660","span":{"begin":117,"end":119},"obj":"TO"},{"id":"T659","span":{"begin":111,"end":116},"obj":"VBN"},{"id":"T658","span":{"begin":108,"end":110},"obj":"VBZ"},{"id":"T657","span":{"begin":103,"end":107},"obj":"NNP"},{"id":"T656","span":{"begin":101,"end":102},"obj":"."},{"id":"T655","span":{"begin":98,"end":101},"obj":"NN"},{"id":"T654","span":{"begin":91,"end":97},"obj":"JJ"},{"id":"T653","span":{"begin":81,"end":90},"obj":"VBG"},{"id":"T652","span":{"begin":75,"end":80},"obj":"NNS"},{"id":"T651","span":{"begin":62,"end":74},"obj":"NN"},{"id":"T650","span":{"begin":56,"end":61},"obj":"JJ"},{"id":"T649","span":{"begin":53,"end":55},"obj":"IN"},{"id":"T648","span":{"begin":43,"end":52},"obj":"NN"},{"id":"T647","span":{"begin":35,"end":42},"obj":"VBZ"},{"id":"T646","span":{"begin":20,"end":34},"obj":"RB"},{"id":"T645","span":{"begin":15,"end":19},"obj":"NNP"},{"id":"T644","span":{"begin":10,"end":14},"obj":"NN"},{"id":"T643","span":{"begin":5,"end":9},"obj":"JJ"},{"id":"T642","span":{"begin":2,"end":4},"obj":"IN"}],"relations":[{"id":"R395","pred":"punct","subj":"T683","obj":"T682"},{"id":"R355","pred":"amod","subj":"T643","obj":"T644"},{"id":"R356","pred":"compound","subj":"T644","obj":"T645"},{"id":"R357","pred":"pobj","subj":"T645","obj":"T642"},{"id":"R358","pred":"advmod","subj":"T646","obj":"T647"},{"id":"R359","pred":"ROOT","subj":"T647","obj":"T647"},{"id":"R360","pred":"dobj","subj":"T648","obj":"T647"},{"id":"R361","pred":"prep","subj":"T649","obj":"T648"},{"id":"R362","pred":"amod","subj":"T650","obj":"T652"},{"id":"R363","pred":"compound","subj":"T651","obj":"T652"},{"id":"R364","pred":"pobj","subj":"T652","obj":"T649"},{"id":"R365","pred":"acl","subj":"T653","obj":"T648"},{"id":"R366","pred":"amod","subj":"T654","obj":"T655"},{"id":"R367","pred":"dobj","subj":"T655","obj":"T653"},{"id":"R368","pred":"punct","subj":"T656","obj":"T647"},{"id":"R369","pred":"nsubjpass","subj":"T657","obj":"T659"},{"id":"R370","pred":"auxpass","subj":"T658","obj":"T659"},{"id":"R371","pred":"ROOT","subj":"T659","obj":"T659"},{"id":"R372","pred":"aux","subj":"T660","obj":"T662"},{"id":"R373","pred":"advmod","subj":"T661","obj":"T662"},{"id":"R374","pred":"xcomp","subj":"T662","obj":"T659"},{"id":"R375","pred":"cc","subj":"T663","obj":"T659"},{"id":"R376","pred":"conj","subj":"T664","obj":"T659"},{"id":"R377","pred":"amod","subj":"T665","obj":"T666"},{"id":"R378","pred":"compound","subj":"T666","obj":"T667"},{"id":"R379","pred":"dobj","subj":"T667","obj":"T664"},{"id":"R380","pred":"punct","subj":"T668","obj":"T659"},{"id":"R381","pred":"advmod","subj":"T669","obj":"T672"},{"id":"R382","pred":"punct","subj":"T670","obj":"T672"},{"id":"R383","pred":"nsubj","subj":"T671","obj":"T672"},{"id":"R384","pred":"ROOT","subj":"T672","obj":"T672"},{"id":"R385","pred":"det","subj":"T673","obj":"T674"},{"id":"R386","pred":"dobj","subj":"T674","obj":"T672"},{"id":"R387","pred":"prep","subj":"T675","obj":"T674"},{"id":"R388","pred":"det","subj":"T676","obj":"T678"},{"id":"R389","pred":"amod","subj":"T677","obj":"T678"},{"id":"R390","pred":"pobj","subj":"T678","obj":"T675"},{"id":"R391","pred":"prep","subj":"T679","obj":"T678"},{"id":"R392","pred":"pobj","subj":"T680","obj":"T679"},{"id":"R393","pred":"cc","subj":"T681","obj":"T680"},{"id":"R394","pred":"conj","subj":"T6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of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    bionlp-st-ge-2016-test-ihmc

    {"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T551","span":{"begin":103,"end":163},"obj":"Binding"},{"id":"T547","span":{"begin":103,"end":163},"obj":"Regulation"},{"id":"T543","span":{"begin":2,"end":19},"obj":"Protein"},{"id":"T540","span":{"begin":56,"end":101},"obj":"Entity"},{"id":"T538","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T527","span":{"begin":91,"end":101},"obj":"Protein"},{"id":"T524","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T522","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T520","span":{"begin":150,"end":163},"obj":"Protein"}],"relations":[{"id":"R259","pred":"themeOf","subj":"T520","obj":"T547"},{"id":"R260","pred":"causeOf","subj":"T524","obj":"T547"},{"id":"R261","pred":"themeOf","subj":"T524","obj":"T551"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    DLUT931

    {"project":"DLUT931","denotations":[{"id":"T420","span":{"begin":131,"end":135},"obj":"Binding"},{"id":"T419","span":{"begin":35,"end":42},"obj":"Positive_regulation"},{"id":"T410","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T409","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T408","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T407","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T406","span":{"begin":15,"end":19},"obj":"Protein"},{"id":"T405","span":{"begin":98,"end":101},"obj":"Protein"}],"relations":[{"id":"R216","pred":"themeOf","subj":"T407","obj":"T420"},{"id":"R217","pred":"themeOf","subj":"T408","obj":"T420"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T470","span":{"begin":131,"end":135},"obj":"Binding"},{"id":"T468","span":{"begin":35,"end":42},"obj":"Positive_regulation"},{"id":"T460","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T459","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T458","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T457","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T456","span":{"begin":15,"end":19},"obj":"Protein"},{"id":"T455","span":{"begin":98,"end":101},"obj":"Protein"}],"relations":[{"id":"R233","pred":"themeOf","subj":"T457","obj":"T470"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T377","span":{"begin":131,"end":135},"obj":"Binding"},{"id":"T376","span":{"begin":140,"end":149},"obj":"Positive_regulation"},{"id":"T368","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T367","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T366","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T365","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T364","span":{"begin":15,"end":19},"obj":"Protein"},{"id":"T363","span":{"begin":98,"end":101},"obj":"Protein"}],"relations":[{"id":"R206","pred":"themeOf","subj":"T365","obj":"T377"},{"id":"R207","pred":"themeOf","subj":"T366","obj":"T376"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T394","span":{"begin":223,"end":226},"obj":"http://www.uniprot.org/uniprot/P04637"},{"id":"T393","span":{"begin":160,"end":163},"obj":"http://www.uniprot.org/uniprot/P04637"},{"id":"T392","span":{"begin":98,"end":101},"obj":"http://www.uniprot.org/uniprot/P04637"},{"id":"T386","span":{"begin":231,"end":235},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"},{"id":"T384","span":{"begin":15,"end":19},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"},{"id":"T385","span":{"begin":103,"end":107},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T126","span":{"begin":15,"end":19},"obj":"Protein"},{"id":"T127","span":{"begin":98,"end":101},"obj":"Protein"},{"id":"T128","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T129","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T130","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T131","span":{"begin":231,"end":235},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    pmc-enju-pas

    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WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T142","span":{"begin":43,"end":52},"obj":"http://purl.obolibrary.org/obo/GO_0097194"},{"id":"T141","span":{"begin":43,"end":52},"obj":"http://purl.obolibrary.org/obo/GO_0006915"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T146","span":{"begin":75,"end":80},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    sentences

    {"project":"sentences","denotations":[{"id":"T84","span":{"begin":103,"end":164},"obj":"Sentence"},{"id":"T7","span":{"begin":103,"end":164},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}

    simple1

    {"project":"simple1","denotations":[{"id":"T161","span":{"begin":231,"end":235},"obj":"Protein"},{"id":"T160","span":{"begin":223,"end":226},"obj":"Protein"},{"id":"T159","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T158","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T157","span":{"begin":98,"end":101},"obj":"Protein"},{"id":"T156","span":{"begin":15,"end":19},"obj":"Protein"}],"text":"n of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. WWOX is known to physically bind and stabilize wild type p53. Here, we provide an overview for the updated knowledge in p53 and WWOX, and postulate potential scenarios that wild"}