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PMC:3586680 / 3054-3750 JSONTXT

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test3

Id Subject Object Predicate Lexical cue
T848 466-470 Protein denotes MGMT
T847 452-462 Gene_expression denotes expression
T846 276-285 Negative_regulation denotes deficient
T845 206-210 Protein denotes MGMT
T844 104-108 Protein denotes MGMT
T843 64-102 Protein denotes O6-methylguanine-DNA methyltransferase
T818 466-470 Protein denotes MGMT
T817 206-210 Protein denotes MGMT
T816 104-108 Protein denotes MGMT
T815 64-102 Protein denotes O6-methylguanine-DNA methyltransferase
R458 T844 T843 equivalentTo MGMT,O6-methylguanine-DNA methyltransferase
R459 T848 T847 themeOf MGMT,expression

testone

Id Subject Object Predicate Lexical cue
T782 466-470 Protein denotes MGMT
T781 206-210 Protein denotes MGMT
T780 104-108 Protein denotes MGMT
T779 64-102 Protein denotes O6-methylguanine-DNA methyltransferase
T803 452-462 Gene_expression denotes expression
T802 276-285 Negative_regulation denotes deficient
R447 T780 T779 equivalentTo MGMT,O6-methylguanine-DNA methyltransferase
R448 T782 T803 themeOf MGMT,expression

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T2282 474-478 Negative_regulation denotes loss
T2281 452-462 Gene_expression denotes expression
T2280 466-470 Protein denotes MGMT
T2279 246-256 Positive_regulation denotes activation
T2278 304-331 Protein denotes Rad3-related protein kinase
T2277 206-210 Protein denotes MGMT
T2276 104-108 Protein denotes MGMT
T2275 64-102 Protein denotes O6-methylguanine-DNA methyltransferase
R1529 T2278 T2279 themeOf Rad3-related protein kinase,activation
R1530 T2280 T2281 themeOf MGMT,expression
R1532 T2281 T2282 themeOf expression,loss

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T3017 695-696 . denotes .
T3016 689-695 NN denotes system
T3015 685-688 NNP denotes MMR
T3014 681-684 DT denotes the
T3013 678-680 IN denotes of
T3012 670-677 NN denotes absence
T3011 666-669 DT denotes the
T3010 663-665 IN denotes in
T3009 657-662 VBZ denotes fails
T3008 647-656 VBG denotes signaling
T3007 637-646 JJ denotes apoptotic
T3006 634-636 IN denotes of
T3005 623-633 NN denotes initiation
T3004 619-622 DT denotes The
T3003 617-618 . denotes .
T3002 616-617 -RRB- denotes )
T3001 612-616 CD denotes 2008
T3000 610-611 , denotes ,
T2999 607-610 FW denotes al.
T2998 604-606 FW denotes et
T2997 595-603 NNP denotes Sarkaria
T2996 593-594 : denotes ;
T2995 589-593 CD denotes 2008
T2994 587-588 , denotes ,
T2993 584-587 FW denotes al.
T2992 581-583 FW denotes et
T2991 576-580 NNP denotes Hegi
T2990 574-575 : denotes ;
T2989 570-574 CD denotes 2006
T2988 568-569 , denotes ,
T2987 565-568 FW denotes al.
T2986 562-564 FW denotes et
T2985 554-561 NNP denotes Pollack
T2984 553-554 -LRB- denotes (
T2983 547-552 NNS denotes cases
T2982 538-546 JJ denotes clinical
T2981 533-537 JJ denotes many
T2980 530-532 IN denotes in
T2979 519-529 NN denotes resistance
T2978 515-518 NNP denotes TMZ
T2977 512-514 TO denotes to
T2976 498-511 RB denotes significantly
T2975 486-497 VBZ denotes contributes
T2974 482-485 NNP denotes MMR
T2973 479-481 IN denotes of
T2972 474-478 NN denotes loss
T2971 471-473 CC denotes or
T2970 466-470 NNP denotes MGMT
T2969 463-465 IN denotes of
T2968 452-462 NN denotes expression
T2967 447-451 NNP denotes High
T2966 445-446 . denotes .
T2965 444-445 -RRB- denotes )
T2964 440-444 CD denotes 2007
T2963 438-439 , denotes ,
T2962 435-438 FW denotes al.
T2961 432-434 FW denotes et
T2960 427-431 NNP denotes Roos
T2959 425-426 : denotes ;
T2958 421-425 CD denotes 2006
T2957 419-420 , denotes ,
T2956 411-419 NNP denotes Edelmann
T2955 407-410 CC denotes and
T2954 402-406 NNP denotes Wang
T2953 400-401 : denotes ;
T2952 396-400 CD denotes 2004
T2951 394-395 , denotes ,
T2950 391-394 FW denotes al.
T2949 388-390 FW denotes et
T2948 379-387 NNP denotes Caporali
T2947 378-379 -LRB- denotes (
T2946 372-377 NN denotes death
T2945 367-371 NN denotes cell
T2944 357-366 JJ denotes apoptotic
T2943 354-356 TO denotes to
T2942 348-353 VBZ denotes leads
T2941 337-347 RB denotes ultimately
T2940 332-336 WDT denotes that
T2939 325-331 NN denotes kinase
T2938 317-324 NN denotes protein
T2937 304-316 JJ denotes Rad3-related
T2936 301-303 CC denotes or
T2935 292-300 NNS denotes proteins
T2934 290-291 -RRB- denotes )
T2933 287-290 NNP denotes MMR
T2932 286-287 -LRB- denotes (
T2931 269-285 NN denotes repair-deficient
T2930 260-268 NN denotes mismatch
T2929 257-259 IN denotes of
T2928 246-256 NN denotes activation
T2927 236-245 NNS denotes initiates
T2926 219-235 JJ denotes O6-methylguanine
T2925 217-218 , denotes ,
T2924 211-217 NN denotes repair
T2923 206-210 NNP denotes MGMT
T2922 198-205 IN denotes Without
T2921 196-197 . denotes .
T2920 195-196 -RRB- denotes )
T2919 190-195 JJ denotes 2012b
T2918 188-189 , denotes ,
T2917 185-188 FW denotes al.
T2916 182-184 FW denotes et
T2915 176-181 NNP denotes Zhang
T2914 174-175 : denotes ;
T2913 170-174 CD denotes 2009
T2912 168-169 , denotes ,
T2911 165-168 FW denotes al.
T2910 162-164 FW denotes et
T2909 152-161 NNP denotes Fukushima
T2908 150-151 : denotes ;
T2907 146-150 CD denotes 2008
T2906 144-145 , denotes ,
T2905 141-144 FW denotes al.
T2904 138-140 FW denotes et
T2903 133-137 NNP denotes Hegi
T2902 131-132 : denotes ;
T2901 127-131 CD denotes 2006
T2900 125-126 , denotes ,
T2899 122-125 FW denotes al.
T2898 119-121 FW denotes et
T2897 111-118 NNP denotes Pollack
T2896 110-111 -LRB- denotes (
T2895 108-109 -RRB- denotes )
T2894 104-108 NNP denotes MGMT
T2893 103-104 -LRB- denotes (
T2892 85-102 NN denotes methyltransferase
T2891 64-84 NNP denotes O6-methylguanine-DNA
T2890 61-63 IN denotes by
T2889 54-60 NN denotes repair
T2888 47-53 JJ denotes direct
T2887 43-46 IN denotes for
T2886 33-42 NN denotes substrate
T2885 31-32 DT denotes a
T2884 28-30 VBZ denotes is
T2883 21-27 NN denotes lesion
T2882 4-20 JJ denotes O6-methylguanine
T2881 0-3 DT denotes The
R1906 T2881 T2883 det The,lesion
R1907 T2882 T2883 amod O6-methylguanine,lesion
R1908 T2883 T2884 nsubj lesion,is
R1909 T2884 T2884 ROOT is,is
R1910 T2885 T2886 det a,substrate
R1912 T2886 T2884 attr substrate,is
R1913 T2887 T2886 prep for,substrate
R1914 T2888 T2889 amod direct,repair
R1916 T2889 T2887 pobj repair,for
R1919 T2890 T2889 prep by,repair
R1921 T2891 T2892 compound O6-methylguanine-DNA,methyltransferase
R1922 T2892 T2890 pobj methyltransferase,by
R1923 T2893 T2894 punct (,MGMT
R1925 T2894 T2892 appos MGMT,methyltransferase
R1926 T2895 T2884 punct ),is
R1928 T2896 T2899 punct (,al.
R1929 T2897 T2899 compound Pollack,al.
R1930 T2898 T2899 nmod et,al.
R1932 T2899 T2905 compound al.,al.
R1933 T2900 T2899 punct ",",al.
R1934 T2901 T2899 npadvmod 2006,al.
R1936 T2902 T2899 punct ;,al.
R1937 T2903 T2905 compound Hegi,al.
R1938 T2904 T2905 compound et,al.
R1940 T2905 T2905 ROOT al.,al.
R1941 T2906 T2905 punct ",",al.
R1944 T2907 T2905 npadvmod 2008,al.
R1945 T2908 T2905 punct ;,al.
R1947 T2909 T2911 compound Fukushima,al.
R1948 T2910 T2911 nmod et,al.
R1949 T2911 T2905 conj al.,al.
R1951 T2912 T2911 punct ",",al.
R1952 T2913 T2911 npadvmod 2009,al.
R1954 T2914 T2917 punct ;,al.
R1955 T2915 T2917 compound Zhang,al.
R1956 T2916 T2917 nmod et,al.
R1957 T2917 T2884 attr al.,is
R1958 T2918 T2919 punct ",",2012b
R1960 T2919 T2917 amod 2012b,al.
R1961 T2920 T2919 punct ),2012b
R1962 T2921 T2884 punct .,is
R1963 T2922 T2927 prep Without,initiates
R1964 T2923 T2924 compound MGMT,repair
R1966 T2924 T2922 pobj repair,Without
R1967 T2925 T2927 punct ",",initiates
R1968 T2926 T2927 nsubj O6-methylguanine,initiates
R1969 T2927 T2927 ROOT initiates,initiates
R1971 T2928 T2927 dobj activation,initiates
R1972 T2929 T2928 prep of,activation
R1973 T2930 T2929 pobj mismatch,of
R1974 T2931 T2928 conj repair-deficient,activation
R1976 T2932 T2931 punct (,repair-deficient
R1977 T2933 T2935 nmod MMR,proteins
R1978 T2934 T2935 punct ),proteins
R1979 T2935 T2931 appos proteins,repair-deficient
R1981 T2936 T2935 cc or,proteins
R1982 T2937 T2939 amod Rad3-related,kinase
R1984 T2938 T2939 compound protein,kinase
R1985 T2939 T2935 conj kinase,proteins
R1986 T2940 T2942 nsubj that,leads
R1988 T2941 T2942 advmod ultimately,leads
R1989 T2942 T2939 relcl leads,kinase
R1990 T2943 T2942 prep to,leads
R1992 T2944 T2946 amod apoptotic,death
R1993 T2945 T2946 compound cell,death
R1994 T2946 T2943 pobj death,to
R1996 T2947 T2950 punct (,al.
R1997 T2948 T2950 compound Caporali,al.
R1998 T2949 T2950 nmod et,al.
R2000 T2950 T2939 appos al.,kinase
R2001 T2951 T2950 punct ",",al.
R2002 T2952 T2950 npadvmod 2004,al.
R2004 T2953 T2927 punct ;,initiates
R2006 T2954 T2927 conj Wang,initiates
R2007 T2955 T2954 cc and,Wang
R2008 T2956 T2954 conj Edelmann,Wang
R2009 T2957 T2956 punct ",",Edelmann
R2013 T2958 T2954 npadvmod 2006,Wang
R2014 T2959 T2954 punct ;,Wang
R2016 T2960 T2962 compound Roos,al.
R2017 T2961 T2962 nmod et,al.
R2019 T2962 T2954 conj al.,Wang
R2020 T2963 T2962 punct ",",al.
R2021 T2964 T2962 npadvmod 2007,al.
R2023 T2965 T2962 punct ),al.
R2024 T2966 T2927 punct .,initiates
R2025 T2967 T2968 compound High,expression
R2026 T2968 T2975 nsubj expression,contributes
R2028 T2969 T2968 prep of,expression
R2029 T2970 T2969 pobj MGMT,of
R2030 T2971 T2970 cc or,MGMT
R2032 T2972 T2968 conj loss,expression
R2033 T2973 T2972 prep of,loss
R2034 T2974 T2973 pobj MMR,of
R2036 T2975 T2999 ccomp contributes,al.
R2037 T2976 T2975 advmod significantly,contributes
R2038 T2977 T2975 prep to,contributes
R2040 T2978 T2979 compound TMZ,resistance
R2041 T2979 T2977 pobj resistance,to
R2042 T2980 T2975 prep in,contributes
R2044 T2981 T2983 amod many,cases
R2045 T2982 T2983 amod clinical,cases
R2047 T2983 T2980 pobj cases,in
R2048 T2984 T2987 punct (,al.
R2049 T2985 T2987 compound Pollack,al.
R2051 T2986 T2987 nmod et,al.
R2054 T2987 T2975 advcl al.,contributes
R2055 T2988 T2987 punct ",",al.
R2057 T2989 T2987 npadvmod 2006,al.
R2058 T2990 T2999 punct ;,al.
R2059 T2991 T2993 compound Hegi,al.
R2060 T2992 T2993 nmod et,al.
R2062 T2993 T2999 ccomp al.,al.
R2063 T2994 T2993 punct ",",al.
R2065 T2995 T2993 npadvmod 2008,al.
R2067 T2996 T2999 punct ;,al.
R2068 T2997 T2999 compound Sarkaria,al.
R2069 T2998 T2999 nmod et,al.
R2071 T2999 T2999 ROOT al.,al.
R2072 T3000 T2999 punct ",",al.
R2073 T3001 T2999 npadvmod 2008,al.
R2075 T3002 T2999 punct ),al.
R2076 T3003 T2999 punct .,al.
R2077 T3004 T3005 det The,initiation
R2078 T3005 T3009 nsubj initiation,fails
R2080 T3006 T3005 prep of,initiation
R2081 T3007 T3008 amod apoptotic,signaling
R2082 T3008 T3006 pobj signaling,of
R2083 T3009 T3009 ROOT fails,fails
R2084 T3010 T3009 prep in,fails
R2086 T3011 T3012 det the,absence
R2087 T3012 T3010 pobj absence,in
R2088 T3013 T3012 prep of,absence
R2090 T3014 T3016 det the,system
R2091 T3015 T3016 compound MMR,system
R2092 T3016 T3013 pobj system,of
R2094 T3017 T3009 punct .,fails

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T2487 427-431 Protein denotes Roos
T2475 61-109 Protein denotes by O6-methylguanine-DNA methyltransferase (MGMT)
T2468 31-109 Entity denotes a substrate for direct repair by O6-methylguanine-DNA methyltransferase (MGMT)
T2461 0-27 Entity denotes The O6-methylguanine lesion
T2453 292-300 Protein denotes proteins
T2452 685-688 Protein denotes MMR
T2450 0-27 Entity denotes The O6-methylguanine lesion
T2446 435-437 Entity denotes al
T2442 219-235 Entity denotes O6-methylguanine
T2439 219-235 Entity denotes O6-methylguanine
T2433 104-108 Protein denotes MGMT
T2431 515-518 Entity denotes TMZ
T2426 317-377 Protein denotes protein kinase that ultimately leads to apoptotic cell death
T2423 466-470 Protein denotes MGMT
T2416 554-567 Entity denotes Pollack et al
T2385 206-210 Protein denotes MGMT

DLUT931

Id Subject Object Predicate Lexical cue
T2190 486-497 Positive_regulation denotes contributes
T2189 474-478 Negative_regulation denotes loss
T2188 452-462 Gene_expression denotes expression
T2166 466-470 Protein denotes MGMT
T2165 206-210 Protein denotes MGMT
T2164 104-108 Protein denotes MGMT
T2163 64-102 Protein denotes O6-methylguanine-DNA methyltransferase
R1494 T2166 T2188 themeOf MGMT,expression
R1504 T2188 T2189 themeOf expression,loss
R1505 T2188 T2190 themeOf expression,contributes

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T2262 452-462 Gene_expression denotes expression
T2261 486-497 Positive_regulation denotes contributes
T2242 466-470 Protein denotes MGMT
T2241 206-210 Protein denotes MGMT
T2240 104-108 Protein denotes MGMT
T2239 64-102 Protein denotes O6-methylguanine-DNA methyltransferase
R1522 T2242 T2262 themeOf MGMT,expression
R1542 T2262 T2261 themeOf expression,contributes

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T2128 486-497 Positive_regulation denotes contributes
T2127 452-462 Gene_expression denotes expression
T2108 466-470 Protein denotes MGMT
T2107 206-210 Protein denotes MGMT
T2106 104-108 Protein denotes MGMT
T2105 64-102 Protein denotes O6-methylguanine-DNA methyltransferase
R1477 T2108 T2127 themeOf MGMT,expression
R1488 T2127 T2128 themeOf expression,contributes

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T2150 466-470 http://www.uniprot.org/uniprot/P16455 denotes MGMT
T2149 206-210 http://www.uniprot.org/uniprot/P16455 denotes MGMT
T2148 104-108 http://www.uniprot.org/uniprot/P16455 denotes MGMT
T2147 81-102 http://www.uniprot.org/uniprot/Q9UBC3 denotes DNA methyltransferase
T2146 81-102 http://www.uniprot.org/uniprot/Q9UIS9 denotes DNA methyltransferase
T2145 81-102 http://www.uniprot.org/uniprot/Q9UBB5 denotes DNA methyltransferase
T2144 81-102 http://www.uniprot.org/uniprot/O95243 denotes DNA methyltransferase
T2143 81-102 http://www.uniprot.org/uniprot/Q9Y6K1 denotes DNA methyltransferase
T2142 81-102 http://www.uniprot.org/uniprot/P26358 denotes DNA methyltransferase

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T1949 466-470 Protein denotes MGMT
T1948 206-210 Protein denotes MGMT
T1947 104-108 Protein denotes MGMT
T1946 64-102 Protein denotes O6-methylguanine-DNA methyltransferase

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T1406 689-695 NN denotes system
T1405 685-688 NN denotes MMR
T1404 681-684 DT denotes the
T1403 678-680 IN denotes of
T1402 670-677 NN denotes absence
T1401 666-669 DT denotes the
T1400 663-665 IN denotes in
T1399 657-662 VB denotes fails
T1398 647-656 NN denotes signaling
T1397 637-646 JJ denotes apoptotic
T1396 634-636 IN denotes of
T1395 623-633 NN denotes initiation
T1394 619-622 DT denotes The
T1393 616-617 -RRB- denotes )
T1392 612-616 CD denotes 2008
T1391 610-611 -COMMA- denotes ,
T1390 607-610 FW denotes al.
T1389 604-606 FW denotes et
T1388 595-603 NNP denotes Sarkaria
T1387 593-594 -COLON- denotes ;
T1386 589-593 CD denotes 2008
T1385 587-588 -COMMA- denotes ,
T1384 584-587 FW denotes al.
T1383 581-583 FW denotes et
T1382 576-580 NNP denotes Hegi
T1381 574-575 -COLON- denotes ;
T1380 570-574 CD denotes 2006
T1379 568-569 -COMMA- denotes ,
T1378 565-568 FW denotes al.
T1377 562-564 FW denotes et
T1376 554-561 NNP denotes Pollack
T1375 553-554 -LRB- denotes (
T1374 547-552 NN denotes cases
T1373 538-546 JJ denotes clinical
T1372 533-537 JJ denotes many
T1371 530-532 IN denotes in
T1370 519-529 NN denotes resistance
T1369 515-518 NN denotes TMZ
T1368 512-514 TO denotes to
T1367 498-511 RB denotes significantly
T1366 486-497 VB denotes contributes
T1365 482-485 NN denotes MMR
T1364 479-481 IN denotes of
T1363 474-478 NN denotes loss
T1362 471-473 CC denotes or
T1361 466-470 NN denotes MGMT
T1360 463-465 IN denotes of
T1359 452-462 NN denotes expression
T1358 447-451 JJ denotes High
T1357 444-445 -RRB- denotes )
T1356 440-444 CD denotes 2007
T1355 438-439 -COMMA- denotes ,
T1354 435-438 FW denotes al.
T1353 432-434 FW denotes et
T1352 427-431 NNP denotes Roos
T1351 425-426 -COLON- denotes ;
T1350 421-425 CD denotes 2006
T1349 419-420 -COMMA- denotes ,
T1348 411-419 NNP denotes Edelmann
T1347 407-410 CC denotes and
T1346 402-406 NNP denotes Wang
T1345 400-401 -COLON- denotes ;
T1344 396-400 CD denotes 2004
T1343 394-395 -COMMA- denotes ,
T1342 391-394 FW denotes al.
T1341 388-390 FW denotes et
T1340 379-387 NNP denotes Caporali
T1339 378-379 -LRB- denotes (
T1320 246-256 NN denotes activation
T1319 236-245 VB denotes initiates
T1318 219-235 NN denotes O6-methylguanine
T1317 217-218 -COMMA- denotes ,
T1316 211-217 NN denotes repair
T1315 206-210 NN denotes MGMT
T1314 198-205 IN denotes Without
T1313 195-196 -RRB- denotes )
T1312 190-195 NN denotes 2012b
T1311 188-189 -COMMA- denotes ,
T1310 185-188 FW denotes al.
T1309 182-184 FW denotes et
T1308 176-181 NNP denotes Zhang
T1307 174-175 -COLON- denotes ;
T1306 170-174 CD denotes 2009
T1305 168-169 -COMMA- denotes ,
T1304 165-168 FW denotes al.
T1303 162-164 FW denotes et
T1302 152-161 NNP denotes Fukushima
T1301 150-151 -COLON- denotes ;
T1300 146-150 CD denotes 2008
T1299 144-145 -COMMA- denotes ,
T1298 141-144 FW denotes al.
T1297 138-140 FW denotes et
T1296 133-137 NNP denotes Hegi
T1295 131-132 -COLON- denotes ;
T1294 127-131 CD denotes 2006
T1293 125-126 -COMMA- denotes ,
T1292 122-125 FW denotes al.
T1291 119-121 FW denotes et
T1290 111-118 NNP denotes Pollack
T1289 110-111 -LRB- denotes (
T1288 108-109 -RRB- denotes )
T1287 104-108 NN denotes MGMT
T1286 103-104 -LRB- denotes (
T1285 85-102 NN denotes methyltransferase
T1284 64-84 NN denotes O6-methylguanine-DNA
T1283 61-63 IN denotes by
T1282 54-60 NN denotes repair
T1281 47-53 JJ denotes direct
T1280 43-46 IN denotes for
T1279 33-42 NN denotes substrate
T1278 31-32 DT denotes a
T1277 28-30 VB denotes is
T1276 21-27 NN denotes lesion
T1275 4-20 NN denotes O6-methylguanine
T1274 0-3 DT denotes The
T1338 372-377 NN denotes death
T1337 367-371 NN denotes cell
T1336 357-366 JJ denotes apoptotic
T1335 354-356 TO denotes to
T1334 348-353 VB denotes leads
T1333 337-347 RB denotes ultimately
T1332 332-336 WDT denotes that
T1331 325-331 NN denotes kinase
T1330 317-324 NN denotes protein
T1329 304-316 JJ denotes Rad3-related
T1328 301-303 CC denotes or
T1327 292-300 NN denotes proteins
T1326 290-291 -RRB- denotes )
T1325 287-290 NN denotes MMR
T1324 286-287 -LRB- denotes (
T1323 269-285 JJ denotes repair-deficient
T1322 260-268 NN denotes mismatch
T1321 257-259 IN denotes of
R829 T1276 T1274 arg1Of lesion,The
R830 T1276 T1275 arg1Of lesion,O6-methylguanine
R831 T1276 T1277 arg1Of lesion,is
R832 T1277 T1289 arg1Of is,(
R833 T1279 T1277 arg2Of substrate,is
R834 T1279 T1278 arg1Of substrate,a
R835 T1279 T1280 arg1Of substrate,for
R836 T1279 T1283 arg1Of substrate,by
R837 T1282 T1280 arg2Of repair,for
R838 T1282 T1281 arg1Of repair,direct
R839 T1285 T1283 arg2Of methyltransferase,by
R840 T1285 T1284 arg1Of methyltransferase,O6-methylguanine-DNA
R841 T1285 T1286 arg1Of methyltransferase,(
R842 T1287 T1286 arg2Of MGMT,(
R843 T1288 T1286 arg3Of ),(
R844 T1290 T1289 arg2Of Pollack,(
R845 T1290 T1291 arg1Of Pollack,et
R846 T1290 T1292 arg1Of Pollack,al.
R847 T1290 T1293 arg1Of Pollack,","
R848 T1290 T1295 arg1Of Pollack,;
R849 T1290 T1301 arg1Of Pollack,;
R850 T1294 T1293 arg2Of 2006,","
R851 T1296 T1295 arg2Of Hegi,;
R852 T1296 T1297 arg1Of Hegi,et
R853 T1296 T1298 arg1Of Hegi,al.
R854 T1296 T1299 arg1Of Hegi,","
R855 T1300 T1299 arg2Of 2008,","
R856 T1302 T1301 arg2Of Fukushima,;
R857 T1302 T1303 arg1Of Fukushima,et
R858 T1302 T1304 arg1Of Fukushima,al.
R859 T1302 T1305 arg1Of Fukushima,","
R860 T1302 T1307 arg1Of Fukushima,;
R861 T1306 T1305 arg2Of 2009,","
R862 T1308 T1307 arg2Of Zhang,;
R863 T1308 T1309 arg1Of Zhang,et
R864 T1308 T1310 arg1Of Zhang,al.
R865 T1308 T1311 arg1Of Zhang,","
R866 T1312 T1311 arg2Of 2012b,","
R867 T1313 T1289 arg3Of ),(
R868 T1316 T1314 arg2Of repair,Without
R869 T1316 T1315 arg1Of repair,MGMT
R870 T1318 T1319 arg1Of O6-methylguanine,initiates
R871 T1319 T1314 arg1Of initiates,Without
R872 T1319 T1317 arg1Of initiates,","
R873 T1320 T1321 arg1Of activation,of
R874 T1320 T1328 arg1Of activation,or
R875 T1325 T1324 arg2Of MMR,(
R876 T1326 T1324 arg3Of ),(
R877 T1327 T1321 arg2Of proteins,of
R878 T1327 T1322 arg1Of proteins,mismatch
R879 T1327 T1323 arg1Of proteins,repair-deficient
R880 T1327 T1324 arg1Of proteins,(
R881 T1328 T1319 arg2Of or,initiates
R882 T1331 T1328 arg2Of kinase,or
R883 T1331 T1329 arg1Of kinase,Rad3-related
R884 T1331 T1330 arg1Of kinase,protein
R885 T1331 T1332 arg1Of kinase,that
R886 T1331 T1334 arg1Of kinase,leads
R887 T1334 T1333 arg1Of leads,ultimately
R888 T1334 T1335 arg1Of leads,to
R889 T1334 T1339 arg1Of leads,(
R890 T1338 T1335 arg2Of death,to
R891 T1338 T1336 arg1Of death,apoptotic
R892 T1338 T1337 arg1Of death,cell
R893 T1340 T1339 arg2Of Caporali,(
R894 T1340 T1341 arg1Of Caporali,et
R895 T1340 T1342 arg1Of Caporali,al.
R896 T1340 T1343 arg1Of Caporali,","
R897 T1340 T1345 arg1Of Caporali,;
R898 T1340 T1351 arg1Of Caporali,;
R899 T1344 T1343 arg2Of 2004,","
R900 T1346 T1347 arg1Of Wang,and
R901 T1347 T1345 arg2Of and,;
R902 T1347 T1349 arg1Of and,","
R903 T1348 T1347 arg2Of Edelmann,and
R904 T1350 T1349 arg2Of 2006,","
R905 T1352 T1351 arg2Of Roos,;
R906 T1352 T1353 arg1Of Roos,et
R907 T1352 T1354 arg1Of Roos,al.
R908 T1352 T1355 arg1Of Roos,","
R909 T1356 T1355 arg2Of 2007,","
R910 T1357 T1339 arg3Of ),(
R911 T1359 T1358 arg1Of expression,High
R912 T1359 T1360 arg1Of expression,of
R913 T1359 T1366 arg1Of expression,contributes
R914 T1361 T1362 arg1Of MGMT,or
R915 T1362 T1360 arg2Of or,of
R916 T1363 T1362 arg2Of loss,or
R917 T1363 T1364 arg1Of loss,of
R918 T1365 T1364 arg2Of MMR,of
R919 T1366 T1367 arg1Of contributes,significantly
R920 T1366 T1368 arg1Of contributes,to
R921 T1366 T1371 arg1Of contributes,in
R922 T1366 T1375 arg1Of contributes,(
R923 T1370 T1368 arg2Of resistance,to
R924 T1370 T1369 arg1Of resistance,TMZ
R925 T1374 T1371 arg2Of cases,in
R926 T1374 T1372 arg1Of cases,many
R927 T1374 T1373 arg1Of cases,clinical
R928 T1376 T1375 arg2Of Pollack,(
R929 T1376 T1377 arg1Of Pollack,et
R930 T1376 T1378 arg1Of Pollack,al.
R931 T1376 T1379 arg1Of Pollack,","
R932 T1376 T1381 arg1Of Pollack,;
R933 T1376 T1387 arg1Of Pollack,;
R934 T1380 T1379 arg2Of 2006,","
R935 T1382 T1381 arg2Of Hegi,;
R936 T1382 T1383 arg1Of Hegi,et
R937 T1382 T1384 arg1Of Hegi,al.
R938 T1382 T1385 arg1Of Hegi,","
R939 T1386 T1385 arg2Of 2008,","
R940 T1388 T1387 arg2Of Sarkaria,;
R941 T1388 T1389 arg1Of Sarkaria,et
R942 T1388 T1390 arg1Of Sarkaria,al.
R943 T1388 T1391 arg1Of Sarkaria,","
R944 T1392 T1391 arg2Of 2008,","
R945 T1393 T1375 arg3Of ),(
R946 T1395 T1394 arg1Of initiation,The
R947 T1395 T1396 arg1Of initiation,of
R948 T1395 T1399 arg1Of initiation,fails
R949 T1398 T1396 arg2Of signaling,of
R950 T1398 T1397 arg1Of signaling,apoptotic
R951 T1399 T1400 arg1Of fails,in
R952 T1400 T1401 arg1Of in,the
R953 T1400 T1403 arg1Of in,of
R954 T1402 T1400 arg2Of absence,in
R955 T1406 T1400 arg3Of system,in
R956 T1406 T1404 arg1Of system,the
R957 T1406 T1405 arg1Of system,MMR

2_test

Id Subject Object Predicate Lexical cue
23459853-16849758-38778497 127-131 16849758 denotes 2006
23459853-18757334-38778498 146-150 18757334 denotes 2008
23459853-20032445-38778499 170-174 20032445 denotes 2009
23459853-15322239-38778501 396-400 15322239 denotes 2004
23459853-16766259-38778502 421-425 16766259 denotes 2006
23459853-16819506-38778503 440-444 16819506 denotes 2007
23459853-16849758-38778504 570-574 16849758 denotes 2006
23459853-18757334-38778505 589-593 18757334 denotes 2008
23459853-18483356-38778506 612-616 18483356 denotes 2008

GO-BP

Id Subject Object Predicate Lexical cue
T2004 647-656 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T2003 685-688 http://purl.obolibrary.org/obo/GO_0006298 denotes MMR
T2002 482-485 http://purl.obolibrary.org/obo/GO_0006298 denotes MMR
T2001 287-290 http://purl.obolibrary.org/obo/GO_0006298 denotes MMR
T2000 260-275 http://purl.obolibrary.org/obo/GO_0006298 denotes mismatch repair
T1999 246-275 http://purl.obolibrary.org/obo/GO_0032425 denotes activation of mismatch repair
T1993 466-470 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T1992 206-210 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T1991 104-108 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T1987 372-377 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T1984 367-377 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T1978 357-377 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptotic cell death

GO-MF

Id Subject Object Predicate Lexical cue
T2020 466-470 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T2019 206-210 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT
T2018 104-108 http://purl.obolibrary.org/obo/GO_0003908 denotes MGMT

sentences

Id Subject Object Predicate Lexical cue
T890 619-696 Sentence denotes The initiation of apoptotic signaling fails in the absence of the MMR system.
T889 447-618 Sentence denotes High expression of MGMT or loss of MMR contributes significantly to TMZ resistance in many clinical cases (Pollack et al., 2006; Hegi et al., 2008; Sarkaria et al., 2008).
T888 198-446 Sentence denotes Without MGMT repair, O6-methylguanine initiates activation of mismatch repair-deficient (MMR) proteins or Rad3-related protein kinase that ultimately leads to apoptotic cell death (Caporali et al., 2004; Wang and Edelmann, 2006; Roos et al., 2007).
T887 0-197 Sentence denotes The O6-methylguanine lesion is a substrate for direct repair by O6-methylguanine-DNA methyltransferase (MGMT) (Pollack et al., 2006; Hegi et al., 2008; Fukushima et al., 2009; Zhang et al., 2012b).
T23 0-197 Sentence denotes The O6-methylguanine lesion is a substrate for direct repair by O6-methylguanine-DNA methyltransferase (MGMT) (Pollack et al., 2006; Hegi et al., 2008; Fukushima et al., 2009; Zhang et al., 2012b).
T24 198-446 Sentence denotes Without MGMT repair, O6-methylguanine initiates activation of mismatch repair-deficient (MMR) proteins or Rad3-related protein kinase that ultimately leads to apoptotic cell death (Caporali et al., 2004; Wang and Edelmann, 2006; Roos et al., 2007).
T25 447-618 Sentence denotes High expression of MGMT or loss of MMR contributes significantly to TMZ resistance in many clinical cases (Pollack et al., 2006; Hegi et al., 2008; Sarkaria et al., 2008).
T26 619-696 Sentence denotes The initiation of apoptotic signaling fails in the absence of the MMR system.

simple1

Id Subject Object Predicate Lexical cue
T2056 466-470 Protein denotes MGMT
T2055 206-210 Protein denotes MGMT
T2054 104-108 Protein denotes MGMT
T2053 64-102 Protein denotes O6-methylguanine-DNA methyltransferase