PMC:3586680 / 22318-22641 JSONTXT

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{"project":"testone","denotations":[{"id":"T9637","span":{"begin":277,"end":287},"obj":"Negative_regulation"},{"id":"T9636","span":{"begin":114,"end":124},"obj":"Regulation"},{"id":"T9622","span":{"begin":272,"end":276},"obj":"Protein"},{"id":"T9621","span":{"begin":181,"end":185},"obj":"Protein"},{"id":"T9620","span":{"begin":106,"end":110},"obj":"Protein"},{"id":"T9619","span":{"begin":98,"end":101},"obj":"Protein"}],"relations":[{"id":"R6578","pred":"themeOf","subj":"T9622","obj":"T9637"}],"text":"In summary, in this perspective article we have discussed the potential role of tumor suppressors p53 and WWOX in regulating TMZ sensitivity in GBM cells. We have shown the role of WWOX in controlling cell migration and metabolic alterations, and discussed the effects of WWOX deficiency and TMZ resistance in cancer cells."}

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summary, in this perspective article we have discussed the potential role of tumor suppressors p53 and WWOX in regulating TMZ sensitivity in GBM cells. 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summary, in this perspective article we have discussed the potential role of tumor suppressors p53 and WWOX in regulating TMZ sensitivity in GBM cells. 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{"project":"GO-BP","denotations":[{"id":"T9935","span":{"begin":201,"end":215},"obj":"http://purl.obolibrary.org/obo/GO_0016477"},{"id":"T9928","span":{"begin":80,"end":97},"obj":"http://purl.obolibrary.org/obo/GO_0051726"}],"text":"In summary, in this perspective article we have discussed the potential role of tumor suppressors p53 and WWOX in regulating TMZ sensitivity in GBM cells. We have shown the role of WWOX in controlling cell migration and metabolic alterations, and discussed the effects of WWOX deficiency and TMZ resistance in cancer cells."}

{"project":"GO-CC","denotations":[{"id":"T9980","span":{"begin":317,"end":322},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T9979","span":{"begin":148,"end":153},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"In summary, in this perspective article we have discussed the potential role of tumor suppressors p53 and WWOX in regulating TMZ sensitivity in GBM cells. We have shown the role of WWOX in controlling cell migration and metabolic alterations, and discussed the effects of WWOX deficiency and TMZ resistance in cancer cells."}

{"project":"sentences","denotations":[{"id":"T9777","span":{"begin":155,"end":323},"obj":"Sentence"},{"id":"T9776","span":{"begin":0,"end":154},"obj":"Sentence"},{"id":"T158","span":{"begin":0,"end":154},"obj":"Sentence"},{"id":"T159","span":{"begin":155,"end":323},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In summary, in this perspective article we have discussed the potential role of tumor suppressors p53 and WWOX in regulating TMZ sensitivity in GBM cells. We have shown the role of WWOX in controlling cell migration and metabolic alterations, and discussed the effects of WWOX deficiency and TMZ resistance in cancer cells."}

{"project":"simple1","denotations":[{"id":"T10068","span":{"begin":272,"end":276},"obj":"Protein"},{"id":"T10067","span":{"begin":181,"end":185},"obj":"Protein"},{"id":"T10066","span":{"begin":106,"end":110},"obj":"Protein"},{"id":"T10065","span":{"begin":98,"end":101},"obj":"Protein"}],"text":"In summary, in this perspective article we have discussed the potential role of tumor suppressors p53 and WWOX in regulating TMZ sensitivity in GBM cells. We have shown the role of WWOX in controlling cell migration and metabolic alterations, and discussed the effects of WWOX deficiency and TMZ resistance in cancer cells."}