PMC:3586680 / 134-663 JSONTXT

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    test3

    {"project":"test3","denotations":[{"id":"T69","span":{"begin":526,"end":529},"obj":"Protein"},{"id":"T68","span":{"begin":443,"end":447},"obj":"Protein"},{"id":"T67","span":{"begin":248,"end":252},"obj":"Protein"},{"id":"T66","span":{"begin":240,"end":244},"obj":"Negative_regulation"},{"id":"T65","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T64","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T63","span":{"begin":154,"end":158},"obj":"Protein"},{"id":"T62","span":{"begin":118,"end":153},"obj":"Protein"},{"id":"T50","span":{"begin":526,"end":529},"obj":"Protein"},{"id":"T49","span":{"begin":443,"end":447},"obj":"Protein"},{"id":"T48","span":{"begin":248,"end":252},"obj":"Protein"},{"id":"T47","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T46","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T45","span":{"begin":154,"end":158},"obj":"Protein"},{"id":"T44","span":{"begin":118,"end":153},"obj":"Protein"}],"relations":[{"id":"R5","pred":"themeOf","subj":"T63","obj":"T64"},{"id":"R6","pred":"equivalentTo","subj":"T64","obj":"T62"}],"text":"n glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    testone

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    bionlp-st-ge-2016-test-tees

    {"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T485","span":{"begin":419,"end":429},"obj":"Gene_expression"},{"id":"T484","span":{"begin":438,"end":447},"obj":"Protein"},{"id":"T483","span":{"begin":387,"end":395},"obj":"Negative_regulation"},{"id":"T482","span":{"begin":240,"end":244},"obj":"Negative_regulation"},{"id":"T481","span":{"begin":258,"end":268},"obj":"Gene_expression"},{"id":"T480","span":{"begin":248,"end":257},"obj":"Protein"},{"id":"T479","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T478","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T477","span":{"begin":139,"end":158},"obj":"Protein"}],"relations":[{"id":"R239","pred":"themeOf","subj":"T480","obj":"T481"},{"id":"R240","pred":"themeOf","subj":"T481","obj":"T482"},{"id":"R241","pred":"themeOf","subj":"T482","obj":"T483"},{"id":"R242","pred":"themeOf","subj":"T484","obj":"T485"}],"text":"n glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    bionlp-st-ge-2016-spacy-parsed

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glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    bionlp-st-ge-2016-test-ihmc

    {"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T550","span":{"begin":245,"end":268},"obj":"Gene_expression"},{"id":"T549","span":{"begin":411,"end":447},"obj":"Gene_expression"},{"id":"T543","span":{"begin":430,"end":447},"obj":"Protein"},{"id":"T541","span":{"begin":176,"end":198},"obj":"Protein"},{"id":"T540","span":{"begin":484,"end":529},"obj":"Entity"},{"id":"T539","span":{"begin":248,"end":252},"obj":"Protein"},{"id":"T537","span":{"begin":118,"end":153},"obj":"Protein"},{"id":"T535","span":{"begin":76,"end":94},"obj":"Entity"},{"id":"T534","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T533","span":{"begin":321,"end":329},"obj":"Entity"},{"id":"T532","span":{"begin":118,"end":158},"obj":"Protein"},{"id":"T531","span":{"begin":220,"end":238},"obj":"Protein"},{"id":"T527","span":{"begin":519,"end":529},"obj":"Protein"},{"id":"T526","span":{"begin":99,"end":116},"obj":"Entity"},{"id":"T523","span":{"begin":90,"end":93},"obj":"Entity"},{"id":"T521","span":{"begin":291,"end":313},"obj":"Entity"}],"relations":[{"id":"R262","pred":"themeOf","subj":"T539","obj":"T550"},{"id":"R263","pred":"themeOf","subj":"T543","obj":"T549"}],"text":"n glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    DLUT931

    {"project":"DLUT931","denotations":[{"id":"T419","span":{"begin":463,"end":470},"obj":"Positive_regulation"},{"id":"T418","span":{"begin":419,"end":429},"obj":"Gene_expression"},{"id":"T417","span":{"begin":240,"end":244},"obj":"Negative_regulation"},{"id":"T416","span":{"begin":258,"end":268},"obj":"Gene_expression"},{"id":"T406","span":{"begin":443,"end":447},"obj":"Protein"},{"id":"T405","span":{"begin":526,"end":529},"obj":"Protein"},{"id":"T404","span":{"begin":248,"end":252},"obj":"Protein"},{"id":"T403","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T402","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T401","span":{"begin":154,"end":158},"obj":"Protein"},{"id":"T400","span":{"begin":118,"end":153},"obj":"Protein"}],"relations":[{"id":"R214","pred":"themeOf","subj":"T404","obj":"T416"},{"id":"R215","pred":"themeOf","subj":"T406","obj":"T418"},{"id":"R222","pred":"themeOf","subj":"T416","obj":"T417"},{"id":"R223","pred":"themeOf","subj":"T418","obj":"T419"}],"text":"n glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T469","span":{"begin":419,"end":429},"obj":"Gene_expression"},{"id":"T468","span":{"begin":463,"end":470},"obj":"Positive_regulation"},{"id":"T467","span":{"begin":240,"end":244},"obj":"Negative_regulation"},{"id":"T466","span":{"begin":258,"end":268},"obj":"Gene_expression"},{"id":"T456","span":{"begin":443,"end":447},"obj":"Protein"},{"id":"T455","span":{"begin":526,"end":529},"obj":"Protein"},{"id":"T454","span":{"begin":248,"end":252},"obj":"Protein"},{"id":"T453","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T452","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T451","span":{"begin":154,"end":158},"obj":"Protein"},{"id":"T450","span":{"begin":118,"end":153},"obj":"Protein"}],"relations":[{"id":"R231","pred":"themeOf","subj":"T454","obj":"T466"},{"id":"R232","pred":"themeOf","subj":"T456","obj":"T469"},{"id":"R236","pred":"themeOf","subj":"T466","obj":"T467"},{"id":"R237","pred":"themeOf","subj":"T469","obj":"T468"}],"text":"n glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T375","span":{"begin":419,"end":429},"obj":"Gene_expression"},{"id":"T374","span":{"begin":258,"end":268},"obj":"Gene_expression"},{"id":"T373","span":{"begin":240,"end":244},"obj":"Negative_regulation"},{"id":"T364","span":{"begin":443,"end":447},"obj":"Protein"},{"id":"T363","span":{"begin":526,"end":529},"obj":"Protein"},{"id":"T362","span":{"begin":248,"end":252},"obj":"Protein"},{"id":"T361","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T360","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T359","span":{"begin":154,"end":158},"obj":"Protein"},{"id":"T358","span":{"begin":118,"end":153},"obj":"Protein"}],"relations":[{"id":"R204","pred":"themeOf","subj":"T362","obj":"T374"},{"id":"R205","pred":"themeOf","subj":"T364","obj":"T375"},{"id":"R210","pred":"themeOf","subj":"T374","obj":"T373"}],"text":"n glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T392","span":{"begin":526,"end":529},"obj":"http://www.uniprot.org/uniprot/P04637"},{"id":"T389","span":{"begin":167,"end":171},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"},{"id":"T388","span":{"begin":160,"end":163},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"},{"id":"T382","span":{"begin":154,"end":158},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"},{"id":"T383","span":{"begin":248,"end":252},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"},{"id":"T384","span":{"begin":443,"end":447},"obj":"http://www.uniprot.org/uniprot/Q9NZC7"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"n glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T121","span":{"begin":118,"end":153},"obj":"Protein"},{"id":"T122","span":{"begin":154,"end":158},"obj":"Protein"},{"id":"T123","span":{"begin":160,"end":163},"obj":"Protein"},{"id":"T124","span":{"begin":167,"end":171},"obj":"Protein"},{"id":"T125","span":{"begin":248,"end":252},"obj":"Protein"},{"id":"T126","span":{"begin":443,"end":447},"obj":"Protein"},{"id":"T127","span":{"begin":526,"end":529},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"n glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

    pmc-enju-pas

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glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene expression is frequently seen in malignant cancer cells due to promoter hypermethylation, genetic alterations, and translational blockade. Intriguingly, ectopic expression of wild type WWOX preferentially induces apoptosis in human glioblastoma cells harboring mutant p53"}

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    simple1

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