PMC:3586680 / 0-417 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/3586680","sourcedb":"PMC","sourceid":"3586680","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3586680","text":"Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas\n\nAbstract\nTumor suppressor p53 are frequently mutated in glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide (TMZ) and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. 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