> top > docs > PMC:3585731 > spans > 8204-9191 > annotations

PMC:3585731 / 8204-9191 JSONTXT

Annnotations TAB JSON ListView MergeView

testone

Id Subject Object Predicate Lexical cue
T2888 407-414 Positive_regulation denotes induced
T2887 90-99 Negative_regulation denotes inhibitor
T2879 887-891 Protein denotes RIP1
T2878 842-846 Protein denotes bFGF
T2877 788-792 Protein denotes TNFα
T2876 649-653 Protein denotes RIP1
T2875 503-507 Protein denotes RIP1
T2874 402-406 Protein denotes TNFα
T2873 103-107 Protein denotes RIP1
R1987 T2873 T2887 themeOf RIP1,inhibitor
R1988 T2874 T2888 causeOf TNFα,induced

2_test

Id Subject Object Predicate Lexical cue
23469174-18408713-90505424 143-145 18408713 denotes 23
23469174-16153840-90505425 149-151 16153840 denotes 24
23469174-22695613-90505426 255-257 22695613 denotes 15
23469174-18408713-90505427 691-693 18408713 denotes 23

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T3760 976-986 NN denotes conditions
T3759 971-975 JJ denotes free
T3758 965-970 NN denotes serum
T3704 661-671 JJ denotes inhibitory
T3703 654-660 NN denotes kinase
T3702 649-653 NN denotes RIP1
T3701 646-648 IN denotes of
T3700 641-645 NN denotes loss
T3699 632-640 JJ denotes complete
T3698 625-631 RB denotes almost
T3697 622-624 TO denotes to
T3696 616-621 VB denotes leads
T3695 611-615 WDT denotes that
T3694 605-610 NN denotes group
T3693 596-604 NN denotes N-methyl
T3692 590-595 JJ denotes extra
T3691 587-589 DT denotes an
T3690 578-586 VB denotes contains
T3689 572-577 WDT denotes which
T3688 570-571 -COMMA- denotes ,
T3687 569-570 -RRB- denotes )
T3686 566-569 NN denotes S1A
T3685 561-565 NN denotes Fig.
T3684 560-561 -LRB- denotes (
T3683 558-559 -RRB- denotes )
T3682 552-558 NN denotes Nec-1i
T3681 551-552 -LRB- denotes (
T3680 537-550 NN denotes 7-Cl-O-Nec-1i
T3679 535-536 -COMMA- denotes ,
T3678 529-535 NN denotes analog
T3677 520-528 JJ denotes inactive
T3676 517-519 DT denotes an
T3675 512-516 VB denotes used
T3674 509-511 PRP denotes we
T3673 507-508 -COMMA- denotes ,
T3672 503-507 NN denotes RIP1
T3671 500-502 IN denotes of
T3670 495-499 NN denotes role
T3669 491-494 DT denotes the
T3668 482-490 VB denotes validate
T3667 474-481 RB denotes further
T3666 471-473 TO denotes To
T3665 468-469 -RRB- denotes )
T3664 465-468 NN denotes S1B
T3663 463-464 -COMMA- denotes ,
T3662 461-463 NN denotes 1B
T3661 456-460 NNP denotes Fig.
T3660 455-456 -LRB- denotes (
T3659 444-454 NN denotes conditions
T3658 438-443 NN denotes serum
T3657 433-437 JJ denotes full
T3656 427-432 IN denotes under
T3655 415-426 NN denotes necroptosis
T3654 402-414 JJ denotes TNFα-induced
T3653 398-401 CC denotes and
T3652 389-397 NN denotes zVAD.fmk
T3651 384-388 CC denotes both
T3650 380-383 CC denotes and
T3649 374-379 NN denotes cells
T3648 369-373 NN denotes L929
T3647 366-368 IN denotes in
T3646 355-365 NN denotes conditions
T3645 350-354 JJ denotes free
T3644 344-349 NN denotes serum
T3643 338-343 IN denotes under
T3642 326-337 NN denotes necroptosis
T3641 302-325 JJ denotes factor/zVAD.fmk-induced
T3640 295-301 NN denotes growth
T3639 287-294 VB denotes blocked
T3638 275-286 RB denotes efficiently
T3637 265-274 NN denotes inhibitor
T3636 260-264 DT denotes This
T3635 257-258 -RRB- denotes ]
T3634 255-257 CD denotes 15
T3633 254-255 -LRB- denotes [
T3632 246-253 NN denotes kinases
T3631 240-245 JJ denotes human
T3630 236-239 CD denotes 400
T3629 231-235 IN denotes than
T3628 226-230 JJ denotes more
T3627 223-225 IN denotes of
T3626 217-222 NN denotes panel
T3625 215-216 DT denotes a
T3624 207-214 IN denotes against
T3623 197-206 VB denotes validated
T3622 189-196 RB denotes further
T3621 184-188 VB denotes been
T3620 180-183 VB denotes has
T3619 168-179 NN denotes selectivity
T3618 164-167 PRP-DOLLAR- denotes its
T3617 162-163 -COMMA- denotes ,
T3616 154-162 RB denotes Recently
T3615 151-152 -RRB- denotes ]
T3614 149-151 CD denotes 24
T3613 148-149 -LRB- denotes [
T3612 146-147 -COMMA- denotes ,
T3611 145-146 -RRB- denotes ]
T3610 143-145 CD denotes 23
T3609 142-143 -LRB- denotes [
T3608 140-141 -RRB- denotes )
T3607 137-140 NN denotes S1A
T3606 132-136 NN denotes Fig.
T3605 131-132 -LRB- denotes (
T3604 119-130 NN denotes necroptosis
T3603 115-118 CC denotes and
T3602 108-114 NN denotes kinase
T3601 103-107 NN denotes RIP1
T3600 100-102 IN denotes of
T3599 90-99 NN denotes inhibitor
T3598 80-89 JJ denotes selective
T3597 76-79 CC denotes and
T3596 69-75 JJ denotes potent
T3595 67-68 DT denotes a
T3594 64-66 IN denotes as
T3593 62-63 -RRB- denotes )
T3592 57-62 NN denotes Nec-1
T3591 56-57 -LRB- denotes (
T3590 43-55 NN denotes 7-Cl-O-Nec-1
T3589 40-42 IN denotes of
T3588 28-39 NN denotes development
T3587 24-27 DT denotes the
T3586 14-23 VB denotes described
T3585 11-13 PRP denotes we
T3584 0-10 RB denotes Previously
T3757 961-964 CC denotes and
T3756 955-960 NN denotes serum
T3755 950-954 CC denotes both
T3754 944-949 IN denotes under
T3753 938-943 NN denotes cells
T3752 933-937 NN denotes L929
T3751 930-932 IN denotes in
T3750 918-929 NN denotes necroptosis
T3749 914-917 IN denotes for
T3748 902-913 JJ denotes responsible
T3747 899-901 VB denotes is
T3746 892-898 NN denotes kinase
T3745 887-891 NN denotes RIP1
T3744 882-886 IN denotes that
T3743 873-881 VB denotes confirms
T3742 868-872 DT denotes This
T3741 865-866 -RRB- denotes )
T3740 862-865 NN denotes S1C
T3739 857-861 NN denotes Fig.
T3738 856-857 -LRB- denotes (
T3737 842-855 NN denotes bFGF/zVAD.fmk
T3736 837-841 IN denotes with
T3735 829-836 VB denotes treated
T3734 818-828 NN denotes conditions
T3733 813-817 JJ denotes free
T3732 807-812 NN denotes serum
T3731 804-806 CC denotes or
T3730 802-803 -RRB- denotes )
T3729 799-802 NN denotes S1B
T3728 794-798 NN denotes Fig.
T3727 793-794 -LRB- denotes (
T3726 788-792 NN denotes TNFα
T3725 785-787 CC denotes or
T3724 776-784 NN denotes zVAD.fmk
T3723 771-775 IN denotes with
T3722 763-770 VB denotes treated
T3721 753-762 NN denotes condtions
T3720 747-752 NN denotes serum
T3719 741-746 IN denotes under
T3718 735-740 NN denotes death
T3717 730-734 NN denotes cell
T3716 725-729 NN denotes L929
T3715 717-724 VB denotes protect
T3714 714-716 TO denotes to
T3713 707-713 JJ denotes unable
T3712 703-706 VB denotes was
T3711 696-702 NN denotes Nec-1i
T3710 693-694 -RRB- denotes ]
T3709 691-693 CD denotes 23
T3708 690-691 -LRB- denotes [
T3707 684-689 FW denotes vitro
T3706 681-683 FW denotes in
T3705 672-680 NN denotes activity
R2388 T3585 T3586 arg1Of we,described
R2389 T3586 T3584 arg1Of described,Previously
R2390 T3586 T3594 arg1Of described,as
R2391 T3586 T3612 arg1Of described,","
R2392 T3586 T3613 arg1Of described,[
R2393 T3588 T3586 arg2Of development,described
R2394 T3588 T3587 arg1Of development,the
R2395 T3588 T3589 arg1Of development,of
R2396 T3590 T3589 arg2Of 7-Cl-O-Nec-1,of
R2397 T3590 T3591 arg1Of 7-Cl-O-Nec-1,(
R2398 T3592 T3591 arg2Of Nec-1,(
R2399 T3593 T3591 arg3Of ),(
R2400 T3596 T3597 arg1Of potent,and
R2401 T3598 T3597 arg2Of selective,and
R2402 T3599 T3594 arg2Of inhibitor,as
R2403 T3599 T3595 arg1Of inhibitor,a
R2404 T3599 T3596 arg1Of inhibitor,potent
R2405 T3599 T3598 arg1Of inhibitor,selective
R2406 T3599 T3600 arg1Of inhibitor,of
R2407 T3602 T3601 arg1Of kinase,RIP1
R2408 T3602 T3603 arg1Of kinase,and
R2409 T3603 T3600 arg2Of and,of
R2410 T3604 T3603 arg2Of necroptosis,and
R2411 T3604 T3605 arg1Of necroptosis,(
R2412 T3604 T3609 arg1Of necroptosis,[
R2413 T3607 T3605 arg2Of S1A,(
R2414 T3607 T3606 arg1Of S1A,Fig.
R2415 T3608 T3605 arg3Of ),(
R2416 T3610 T3609 arg2Of 23,[
R2417 T3611 T3609 arg3Of ],[
R2418 T3614 T3613 arg2Of 24,[
R2419 T3615 T3613 arg3Of ],[
R2420 T3619 T3618 arg1Of selectivity,its
R2421 T3619 T3620 arg1Of selectivity,has
R2422 T3619 T3621 arg1Of selectivity,been
R2423 T3619 T3623 arg2Of selectivity,validated
R2424 T3623 T3616 arg1Of validated,Recently
R2425 T3623 T3617 arg1Of validated,","
R2426 T3623 T3620 arg2Of validated,has
R2427 T3623 T3621 arg2Of validated,been
R2428 T3623 T3622 arg1Of validated,further
R2429 T3623 T3624 arg1Of validated,against
R2430 T3626 T3624 arg2Of panel,against
R2431 T3626 T3625 arg1Of panel,a
R2432 T3626 T3627 arg1Of panel,of
R2433 T3628 T3629 arg1Of more,than
R2434 T3630 T3629 arg2Of 400,than
R2435 T3632 T3627 arg2Of kinases,of
R2436 T3632 T3628 arg1Of kinases,more
R2437 T3632 T3631 arg1Of kinases,human
R2438 T3632 T3633 arg1Of kinases,[
R2439 T3634 T3633 arg2Of 15,[
R2440 T3635 T3633 arg3Of ],[
R2441 T3637 T3636 arg1Of inhibitor,This
R2442 T3637 T3639 arg1Of inhibitor,blocked
R2443 T3639 T3638 arg1Of blocked,efficiently
R2444 T3639 T3643 arg1Of blocked,under
R2445 T3642 T3639 arg2Of necroptosis,blocked
R2446 T3642 T3640 arg1Of necroptosis,growth
R2447 T3642 T3641 arg1Of necroptosis,factor/zVAD.fmk-induced
R2448 T3646 T3644 arg1Of conditions,serum
R2449 T3646 T3645 arg1Of conditions,free
R2450 T3646 T3647 arg1Of conditions,in
R2451 T3646 T3650 arg1Of conditions,and
R2452 T3649 T3647 arg2Of cells,in
R2453 T3649 T3648 arg1Of cells,L929
R2454 T3650 T3643 arg2Of and,under
R2455 T3652 T3653 arg1Of zVAD.fmk,and
R2456 T3653 T3650 arg2Of and,and
R2457 T3653 T3651 arg1Of and,both
R2458 T3653 T3656 arg1Of and,under
R2459 T3655 T3653 arg2Of necroptosis,and
R2460 T3655 T3654 arg1Of necroptosis,TNFα-induced
R2461 T3659 T3656 arg2Of conditions,under
R2462 T3659 T3657 arg1Of conditions,full
R2463 T3659 T3658 arg1Of conditions,serum
R2464 T3659 T3660 arg1Of conditions,(
R2465 T3662 T3660 arg2Of 1B,(
R2466 T3662 T3661 arg1Of 1B,Fig.
R2467 T3662 T3663 arg1Of 1B,","
R2468 T3664 T3663 arg2Of S1B,","
R2469 T3665 T3660 arg3Of ),(
R2470 T3668 T3666 arg1Of validate,To
R2471 T3668 T3667 arg1Of validate,further
R2472 T3670 T3668 arg2Of role,validate
R2473 T3670 T3669 arg1Of role,the
R2474 T3670 T3671 arg1Of role,of
R2475 T3672 T3671 arg2Of RIP1,of
R2476 T3674 T3668 arg1Of we,validate
R2477 T3674 T3675 arg1Of we,used
R2478 T3675 T3666 modOf used,To
R2479 T3675 T3673 arg1Of used,","
R2480 T3678 T3675 arg2Of analog,used
R2481 T3678 T3676 arg1Of analog,an
R2482 T3678 T3677 arg1Of analog,inactive
R2483 T3678 T3679 arg1Of analog,","
R2484 T3680 T3679 arg2Of 7-Cl-O-Nec-1i,","
R2485 T3680 T3681 arg1Of 7-Cl-O-Nec-1i,(
R2486 T3680 T3684 arg1Of 7-Cl-O-Nec-1i,(
R2487 T3680 T3688 arg1Of 7-Cl-O-Nec-1i,","
R2488 T3680 T3689 arg1Of 7-Cl-O-Nec-1i,which
R2489 T3680 T3690 arg1Of 7-Cl-O-Nec-1i,contains
R2490 T3682 T3681 arg2Of Nec-1i,(
R2491 T3683 T3681 arg3Of ),(
R2492 T3686 T3684 arg2Of S1A,(
R2493 T3686 T3685 arg1Of S1A,Fig.
R2494 T3687 T3684 arg3Of ),(
R2495 T3694 T3690 arg2Of group,contains
R2496 T3694 T3691 arg1Of group,an
R2497 T3694 T3692 arg1Of group,extra
R2498 T3694 T3693 arg1Of group,N-methyl
R2499 T3694 T3695 arg1Of group,that
R2500 T3694 T3696 arg1Of group,leads
R2501 T3696 T3697 arg1Of leads,to
R2502 T3696 T3708 arg1Of leads,[
R2503 T3699 T3698 arg1Of complete,almost
R2504 T3700 T3697 arg2Of loss,to
R2505 T3700 T3699 arg1Of loss,complete
R2506 T3700 T3701 arg1Of loss,of
R2507 T3700 T3707 arg1Of loss,vitro
R2508 T3705 T3701 arg2Of activity,of
R2509 T3705 T3702 arg1Of activity,RIP1
R2510 T3705 T3703 arg1Of activity,kinase
R2511 T3705 T3704 arg1Of activity,inhibitory
R2512 T3707 T3706 arg1Of vitro,in
R2513 T3709 T3708 arg2Of 23,[
R2514 T3710 T3708 arg3Of ],[
R2515 T3711 T3712 arg1Of Nec-1i,was
R2516 T3711 T3713 arg1Of Nec-1i,unable
R2517 T3711 T3715 arg1Of Nec-1i,protect
R2518 T3713 T3712 arg2Of unable,was
R2519 T3715 T3713 arg2Of protect,unable
R2520 T3715 T3714 arg1Of protect,to
R2521 T3715 T3719 arg1Of protect,under
R2522 T3718 T3715 arg2Of death,protect
R2523 T3718 T3716 arg1Of death,L929
R2524 T3718 T3717 arg1Of death,cell
R2525 T3721 T3720 arg1Of condtions,serum
R2526 T3721 T3722 arg2Of condtions,treated
R2527 T3721 T3731 arg1Of condtions,or
R2528 T3722 T3723 arg1Of treated,with
R2529 T3724 T3725 arg1Of zVAD.fmk,or
R2530 T3725 T3723 arg2Of or,with
R2531 T3725 T3727 arg1Of or,(
R2532 T3726 T3725 arg2Of TNFα,or
R2533 T3729 T3727 arg2Of S1B,(
R2534 T3729 T3728 arg1Of S1B,Fig.
R2535 T3730 T3727 arg3Of ),(
R2536 T3731 T3719 arg2Of or,under
R2537 T3734 T3731 arg2Of conditions,or
R2538 T3734 T3732 arg1Of conditions,serum
R2539 T3734 T3733 arg1Of conditions,free
R2540 T3734 T3735 arg2Of conditions,treated
R2541 T3735 T3736 arg1Of treated,with
R2542 T3737 T3736 arg2Of bFGF/zVAD.fmk,with
R2543 T3737 T3738 arg1Of bFGF/zVAD.fmk,(
R2544 T3740 T3738 arg2Of S1C,(
R2545 T3740 T3739 arg1Of S1C,Fig.
R2546 T3741 T3738 arg3Of ),(
R2547 T3742 T3743 arg1Of This,confirms
R2548 T3746 T3745 arg1Of kinase,RIP1
R2549 T3746 T3747 arg1Of kinase,is
R2550 T3746 T3748 arg1Of kinase,responsible
R2551 T3747 T3743 arg2Of is,confirms
R2552 T3747 T3744 arg1Of is,that
R2553 T3748 T3747 arg2Of responsible,is
R2554 T3748 T3749 arg1Of responsible,for
R2555 T3748 T3754 arg1Of responsible,under
R2556 T3750 T3749 arg2Of necroptosis,for
R2557 T3750 T3751 arg1Of necroptosis,in
R2558 T3753 T3751 arg2Of cells,in
R2559 T3753 T3752 arg1Of cells,L929
R2560 T3756 T3757 arg1Of serum,and
R2561 T3757 T3754 arg2Of and,under
R2562 T3757 T3755 arg1Of and,both
R2563 T3760 T3757 arg2Of conditions,and
R2564 T3760 T3758 arg1Of conditions,serum
R2565 T3760 T3759 arg1Of conditions,free

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T3061 887-891 Protein denotes RIP1
T3060 842-846 Protein denotes bFGF
T3059 788-792 Protein denotes TNFα
T3058 649-653 Protein denotes RIP1
T3057 503-507 Protein denotes RIP1
T3056 402-406 Protein denotes TNFα
T3055 103-107 Protein denotes RIP1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T3968 842-846 http://www.uniprot.org/uniprot/Q788Q8 denotes bFGF
T3964 887-891 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T3963 649-653 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T3962 503-507 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T3961 103-107 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T3957 788-792 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T3956 402-406 http://www.uniprot.org/uniprot/P01375 denotes TNFα

UBERON-AE

Id Subject Object Predicate Lexical cue
T2967 965-970 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T2966 955-960 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T2965 807-812 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T2964 747-752 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T2963 438-443 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T2962 344-349 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

GO-BP

Id Subject Object Predicate Lexical cue
T3139 28-39 http://purl.obolibrary.org/obo/GO_0032502 denotes development
T3130 735-740 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T3121 730-740 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T3111 918-929 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T3110 415-426 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T3109 326-337 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T3108 119-130 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T3091 918-929 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T3090 415-426 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T3089 326-337 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T3088 119-130 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T3074 295-301 http://purl.obolibrary.org/obo/GO_0040007 denotes growth

GO-CC

Id Subject Object Predicate Lexical cue
T3170 938-943 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3169 374-379 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T2987 868-987 Sentence denotes This confirms that RIP1 kinase is responsible for necroptosis in L929 cells under both serum and serum free conditions.
T2986 696-867 Sentence denotes Nec-1i was unable to protect L929 cell death under serum condtions treated with zVAD.fmk or TNFα (Fig. S1B) or serum free conditions treated with bFGF/zVAD.fmk (Fig. S1C).
T2985 471-695 Sentence denotes To further validate the role of RIP1, we used an inactive analog, 7-Cl-O-Nec-1i (Nec-1i) (Fig. S1A), which contains an extra N-methyl group that leads to almost complete loss of RIP1 kinase inhibitory activity in vitro [23].
T2984 260-470 Sentence denotes This inhibitor efficiently blocked growth factor/zVAD.fmk-induced necroptosis under serum free conditions in L929 cells and both zVAD.fmk and TNFα-induced necroptosis under full serum conditions (Fig. 1B, S1B).
T2983 154-259 Sentence denotes Recently, its selectivity has been further validated against a panel of more than 400 human kinases [15].
T2982 0-153 Sentence denotes Previously we described the development of 7-Cl-O-Nec-1 (Nec-1) as a potent and selective inhibitor of RIP1 kinase and necroptosis (Fig. S1A) [23], [24].
T52 0-153 Sentence denotes Previously we described the development of 7-Cl-O-Nec-1 (Nec-1) as a potent and selective inhibitor of RIP1 kinase and necroptosis (Fig. S1A) [23], [24].
T53 154-259 Sentence denotes Recently, its selectivity has been further validated against a panel of more than 400 human kinases [15].
T54 260-470 Sentence denotes This inhibitor efficiently blocked growth factor/zVAD.fmk-induced necroptosis under serum free conditions in L929 cells and both zVAD.fmk and TNFα-induced necroptosis under full serum conditions (Fig. 1B, S1B).
T55 471-695 Sentence denotes To further validate the role of RIP1, we used an inactive analog, 7-Cl-O-Nec-1i (Nec-1i) (Fig. S1A), which contains an extra N-methyl group that leads to almost complete loss of RIP1 kinase inhibitory activity in vitro [23].
T56 696-867 Sentence denotes Nec-1i was unable to protect L929 cell death under serum condtions treated with zVAD.fmk or TNFα (Fig. S1B) or serum free conditions treated with bFGF/zVAD.fmk (Fig. S1C).
T57 868-987 Sentence denotes This confirms that RIP1 kinase is responsible for necroptosis in L929 cells under both serum and serum free conditions.

simple1

Id Subject Object Predicate Lexical cue
T3193 887-891 Protein denotes RIP1
T3192 842-846 Protein denotes bFGF
T3191 788-792 Protein denotes TNFα
T3190 649-653 Protein denotes RIP1
T3189 503-507 Protein denotes RIP1
T3188 402-406 Protein denotes TNFα
T3187 103-107 Protein denotes RIP1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T3950 641-645 Negative_regulation denotes loss
T3949 90-99 Negative_regulation denotes inhibitor
T3939 887-891 Protein denotes RIP1
T3938 842-846 Protein denotes bFGF
T3937 788-792 Protein denotes TNFα
T3936 649-653 Protein denotes RIP1
T3935 503-507 Protein denotes RIP1
T3934 402-406 Protein denotes TNFα
T3933 103-107 Protein denotes RIP1
R2722 T3936 T3950 themeOf RIP1,loss
R2721 T3933 T3949 themeOf RIP1,inhibitor

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T4070 887-891 Protein denotes RIP1
T4069 842-846 Protein denotes bFGF
T4068 788-792 Protein denotes TNFα
T4067 649-653 Protein denotes RIP1
T4066 503-507 Protein denotes RIP1
T4065 402-406 Protein denotes TNFα
T4064 103-107 Protein denotes RIP1
T4079 90-99 Negative_regulation denotes inhibitor
R2747 T4064 T4079 themeOf RIP1,inhibitor

DLUT931

Id Subject Object Predicate Lexical cue
T4010 902-913 Regulation denotes responsible
T4009 641-645 Negative_regulation denotes loss
T4008 90-99 Negative_regulation denotes inhibitor
T3996 887-891 Protein denotes RIP1
T3995 842-846 Protein denotes bFGF
T3994 788-792 Protein denotes TNFα
T3993 649-653 Protein denotes RIP1
T3992 503-507 Protein denotes RIP1
T3991 402-406 Protein denotes TNFα
T3990 103-107 Protein denotes RIP1
R2732 T3990 T4008 themeOf RIP1,inhibitor
R2733 T3993 T4009 themeOf RIP1,loss
R2734 T3996 T4010 themeOf RIP1,responsible

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T4935 842-846 Protein denotes bFGF
T4929 725-729 Entity denotes L929
T4925 649-671 Protein denotes RIP1 kinase inhibitory
T4921 587-680 Entity denotes an extra N-methyl group that leads to almost complete loss of RIP1 kinase inhibitory activity
T4920 456-459 Protein denotes Fig
T4916 776-784 Entity denotes zVAD.fmk
T4982 260-274 Entity denotes This inhibitor
T4980 649-653 Protein denotes RIP1
T4975 389-397 Entity denotes zVAD.fmk
T4972 887-898 Protein denotes RIP1 kinase
T4962 500-507 Protein denotes of RIP1
T4960 57-62 Protein denotes Nec-1
T4957 402-414 Protein denotes TNFα-induced
T4955 847-855 Entity denotes zVAD.fmk
T4949 788-792 Protein denotes TNFα
T4946 69-152 Entity denotes potent and selective inhibitor of RIP1 kinase and necroptosis (Fig. S1A) [23], [24]
T4943 103-114 Protein denotes RIP1 kinase
T4942 887-891 Protein denotes RIP1
T4937 226-258 Protein denotes more than 400 human kinases [15]
T4936 103-107 Protein denotes RIP1

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T4677 842-851 NNP denotes bFGF/zVAD
T4676 837-841 IN denotes with
T4675 829-836 VBN denotes treated
T4674 818-828 NNS denotes conditions
T4673 813-817 JJ denotes free
T4672 807-812 NN denotes serum
T4671 804-806 CC denotes or
T4670 802-803 -RRB- denotes )
T4669 799-802 CD denotes S1B
T4668 797-798 . denotes .
T4667 794-797 NNP denotes Fig
T4666 793-794 -LRB- denotes (
T4665 788-792 NNP denotes TNFα
T4664 785-787 CC denotes or
T4663 776-784 NNP denotes zVAD.fmk
T4662 771-775 IN denotes with
T4661 763-770 VBN denotes treated
T4660 753-762 NNS denotes condtions
T4659 747-752 NN denotes serum
T4658 741-746 IN denotes under
T4657 735-740 NN denotes death
T4656 730-734 NN denotes cell
T4655 725-729 NNP denotes L929
T4654 717-724 VB denotes protect
T4653 714-716 TO denotes to
T4652 707-713 JJ denotes unable
T4651 703-706 VBD denotes was
T4650 696-702 NN denotes Nec-1i
T4649 694-695 . denotes .
T4648 693-694 NNP denotes ]
T4647 691-693 CD denotes 23
T4646 690-691 NNP denotes [
T4645 684-689 NN denotes vitro
T4644 681-683 IN denotes in
T4643 672-680 NN denotes activity
T4642 661-671 NN denotes inhibitory
T4641 654-660 NN denotes kinase
T4640 649-653 CD denotes RIP1
T4639 646-648 IN denotes of
T4638 641-645 NN denotes loss
T4637 632-640 JJ denotes complete
T4636 625-631 RB denotes almost
T4635 622-624 TO denotes to
T4634 616-621 VBZ denotes leads
T4633 611-615 WDT denotes that
T4632 605-610 NN denotes group
T4631 596-604 NN denotes N-methyl
T4630 590-595 JJ denotes extra
T4629 587-589 DT denotes an
T4628 578-586 VBZ denotes contains
T4627 572-577 WDT denotes which
T4626 570-571 , denotes ,
T4625 569-570 -RRB- denotes )
T4624 566-569 CD denotes S1A
T4623 564-565 . denotes .
T4622 561-564 NNP denotes Fig
T4621 560-561 -LRB- denotes (
T4620 558-559 -RRB- denotes )
T4619 552-558 NNP denotes Nec-1i
T4618 551-552 -LRB- denotes (
T4617 537-550 NNP denotes 7-Cl-O-Nec-1i
T4616 535-536 , denotes ,
T4615 529-535 NN denotes analog
T4614 520-528 JJ denotes inactive
T4613 517-519 DT denotes an
T4612 512-516 VBD denotes used
T4611 509-511 PRP denotes we
T4610 507-508 , denotes ,
T4609 503-507 NNP denotes RIP1
T4608 500-502 IN denotes of
T4607 495-499 NN denotes role
T4606 491-494 DT denotes the
T4605 482-490 VB denotes validate
T4604 474-481 RBR denotes further
T4603 471-473 TO denotes To
T4602 469-470 . denotes .
T4601 468-469 -RRB- denotes )
T4600 465-468 NNP denotes S1B
T4599 463-464 , denotes ,
T4598 461-463 NNP denotes 1B
T4597 456-460 NNP denotes Fig.
T4596 455-456 -LRB- denotes (
T4595 444-454 NNS denotes conditions
T4594 438-443 NN denotes serum
T4593 433-437 JJ denotes full
T4592 427-432 IN denotes under
T4591 415-426 NN denotes necroptosis
T4590 402-414 JJ denotes TNFα-induced
T4589 398-401 CC denotes and
T4588 389-397 NNP denotes zVAD.fmk
T4587 384-388 DT denotes both
T4586 380-383 CC denotes and
T4585 374-379 NNS denotes cells
T4584 369-373 NNP denotes L929
T4583 366-368 IN denotes in
T4582 355-365 NNS denotes conditions
T4581 350-354 JJ denotes free
T4580 344-349 NN denotes serum
T4579 338-343 IN denotes under
T4578 326-337 NN denotes necroptosis
T4577 314-325 JJ denotes fmk-induced
T4576 313-314 . denotes .
T4575 302-313 NNP denotes factor/zVAD
T4574 295-301 NN denotes growth
T4573 287-294 VBN denotes blocked
T4572 275-286 RB denotes efficiently
T4571 265-274 NN denotes inhibitor
T4570 260-264 DT denotes This
T4569 258-259 . denotes .
T4568 257-258 NNP denotes ]
T4567 255-257 CD denotes 15
T4566 254-255 NNP denotes [
T4565 246-253 NNS denotes kinases
T4564 240-245 JJ denotes human
T4563 236-239 CD denotes 400
T4562 231-235 IN denotes than
T4561 226-230 JJR denotes more
T4560 223-225 IN denotes of
T4559 217-222 NN denotes panel
T4558 215-216 DT denotes a
T4557 207-214 IN denotes against
T4556 197-206 VBN denotes validated
T4555 189-196 JJ denotes further
T4554 184-188 VBN denotes been
T4553 180-183 VBZ denotes has
T4552 168-179 NN denotes selectivity
T4551 164-167 PRP$ denotes its
T4550 162-163 , denotes ,
T4549 154-162 RB denotes Recently
T4548 152-153 . denotes .
T4547 151-152 NNP denotes ]
T4546 149-151 CD denotes 24
T4545 148-149 NNP denotes [
T4544 146-147 , denotes ,
T4543 145-146 NNP denotes ]
T4542 143-145 CD denotes 23
T4541 142-143 NNP denotes [
T4540 140-141 -RRB- denotes )
T4539 137-140 CD denotes S1A
T4538 135-136 . denotes .
T4537 132-135 NNP denotes Fig
T4536 131-132 -LRB- denotes (
T4535 119-130 NN denotes necroptosis
T4534 115-118 CC denotes and
T4533 108-114 NN denotes kinase
T4532 103-107 CD denotes RIP1
T4531 100-102 IN denotes of
T4530 90-99 NN denotes inhibitor
T4529 80-89 JJ denotes selective
T4528 76-79 CC denotes and
T4527 69-75 JJ denotes potent
T4526 67-68 DT denotes a
T4525 64-66 IN denotes as
T4524 62-63 -RRB- denotes )
T4523 57-62 NNP denotes Nec-1
T4522 56-57 -LRB- denotes (
T4521 43-55 NNP denotes 7-Cl-O-Nec-1
T4520 40-42 IN denotes of
T4519 28-39 NN denotes development
T4518 24-27 DT denotes the
T4517 14-23 VBD denotes described
T4516 11-13 PRP denotes we
T4515 0-10 RB denotes Previously
T4705 986-987 . denotes .
T4704 976-986 NNS denotes conditions
T4703 971-975 JJ denotes free
T4702 965-970 NN denotes serum
T4701 961-964 CC denotes and
T4700 955-960 NN denotes serum
T4699 950-954 DT denotes both
T4698 944-949 IN denotes under
T4697 938-943 NNS denotes cells
T4696 933-937 CD denotes L929
T4695 930-932 IN denotes in
T4694 918-929 NN denotes necroptosis
T4693 914-917 IN denotes for
T4692 902-913 JJ denotes responsible
T4691 899-901 VBZ denotes is
T4690 892-898 NN denotes kinase
T4689 887-891 CD denotes RIP1
T4688 882-886 IN denotes that
T4687 873-881 VBZ denotes confirms
T4686 868-872 DT denotes This
T4685 866-867 . denotes .
T4684 865-866 -RRB- denotes )
T4683 862-865 CD denotes S1C
T4682 860-861 . denotes .
T4681 857-860 NNP denotes Fig
T4680 856-857 -LRB- denotes (
T4679 852-855 NN denotes fmk
T4678 851-852 . denotes .
R3127 T4515 T4517 advmod Previously,described
R3129 T4516 T4517 nsubj we,described
R3132 T4517 T4517 ROOT described,described
R3136 T4518 T4519 det the,development
R3139 T4519 T4517 dobj development,described
R3140 T4520 T4519 prep of,development
R3141 T4521 T4520 pobj 7-Cl-O-Nec-1,of
R3142 T4522 T4521 punct (,7-Cl-O-Nec-1
R3143 T4586 T4582 cc and,conditions
R3144 T4587 T4588 preconj both,zVAD.fmk
R3145 T4523 T4521 appos Nec-1,7-Cl-O-Nec-1
R3146 T4588 T4582 conj zVAD.fmk,conditions
R3147 T4589 T4588 cc and,zVAD.fmk
R3148 T4590 T4591 amod TNFα-induced,necroptosis
R3149 T4591 T4588 conj necroptosis,zVAD.fmk
R3150 T4592 T4582 prep under,conditions
R3151 T4524 T4521 punct ),7-Cl-O-Nec-1
R3152 T4593 T4595 amod full,conditions
R3153 T4594 T4595 compound serum,conditions
R3154 T4595 T4592 pobj conditions,under
R3155 T4596 T4582 punct (,conditions
R3156 T4525 T4517 prep as,described
R3157 T4597 T4598 compound Fig.,1B
R3158 T4598 T4582 appos 1B,conditions
R3159 T4599 T4598 punct ",",1B
R3160 T4526 T4530 det a,inhibitor
R3161 T4600 T4598 appos S1B,1B
R3162 T4601 T4598 punct ),1B
R3163 T4527 T4530 amod potent,inhibitor
R3164 T4602 T4582 punct .,conditions
R3165 T4603 T4605 aux To,validate
R3166 T4604 T4605 advmod further,validate
R3167 T4528 T4527 cc and,potent
R3168 T4605 T4612 advcl validate,used
R3169 T4606 T4607 det the,role
R3170 T4607 T4605 dobj role,validate
R3171 T4529 T4527 conj selective,potent
R3172 T4608 T4607 prep of,role
R3173 T4609 T4608 pobj RIP1,of
R3174 T4530 T4525 pobj inhibitor,as
R3175 T4610 T4612 punct ",",used
R3176 T4611 T4612 nsubj we,used
R3177 T4612 T4612 ROOT used,used
R3178 T4531 T4530 prep of,inhibitor
R3179 T4613 T4615 det an,analog
R3180 T4614 T4615 amod inactive,analog
R3181 T4615 T4612 dobj analog,used
R3182 T4532 T4533 nummod RIP1,kinase
R3183 T4616 T4615 punct ",",analog
R3184 T4617 T4615 appos 7-Cl-O-Nec-1i,analog
R3185 T4618 T4617 punct (,7-Cl-O-Nec-1i
R3186 T4533 T4531 pobj kinase,of
R3187 T4619 T4617 appos Nec-1i,7-Cl-O-Nec-1i
R3188 T4620 T4617 punct ),7-Cl-O-Nec-1i
R3189 T4621 T4622 punct (,Fig
R3190 T4622 T4617 appos Fig,7-Cl-O-Nec-1i
R3191 T4534 T4533 cc and,kinase
R3192 T4623 T4612 punct .,used
R3193 T4535 T4533 conj necroptosis,kinase
R3194 T4624 T4624 ROOT S1A,S1A
R3195 T4536 T4537 punct (,Fig
R3196 T4625 T4624 punct ),S1A
R3197 T4626 T4624 punct ",",S1A
R3198 T4627 T4628 nsubj which,contains
R3199 T4628 T4624 relcl contains,S1A
R3200 T4629 T4632 det an,group
R3201 T4630 T4632 amod extra,group
R3202 T4631 T4632 compound N-methyl,group
R3203 T4537 T4533 appos Fig,kinase
R3204 T4632 T4628 dobj group,contains
R3205 T4633 T4634 nsubj that,leads
R3206 T4634 T4632 relcl leads,group
R3207 T4538 T4517 punct .,described
R3208 T4635 T4634 prep to,leads
R3209 T4636 T4637 advmod almost,complete
R3210 T4539 T4539 ROOT S1A,S1A
R3211 T4637 T4638 amod complete,loss
R3212 T4638 T4635 pobj loss,to
R3213 T4540 T4541 punct ),[
R3214 T4639 T4638 prep of,loss
R3215 T4541 T4543 nmod [,]
R3216 T4640 T4643 nummod RIP1,activity
R3217 T4641 T4643 compound kinase,activity
R3218 T4642 T4643 compound inhibitory,activity
R3219 T4542 T4543 nummod 23,]
R3220 T4643 T4639 pobj activity,of
R3221 T4644 T4638 prep in,loss
R3222 T4645 T4646 amod vitro,[
R3223 T4646 T4644 pobj [,in
R3224 T4543 T4543 ROOT ],]
R3225 T4647 T4648 nummod 23,]
R3226 T4544 T4543 punct ",",]
R3227 T4648 T4646 appos ],[
R3228 T4649 T4624 punct .,S1A
R3229 T4650 T4651 nsubj Nec-1i,was
R3230 T4545 T4547 nmod [,]
R3231 T4651 T4651 ROOT was,was
R3232 T4652 T4651 acomp unable,was
R3233 T4653 T4654 aux to,protect
R3234 T4654 T4652 xcomp protect,unable
R3235 T4546 T4547 nummod 24,]
R3236 T4655 T4657 compound L929,death
R3237 T4656 T4657 compound cell,death
R3238 T4657 T4654 dobj death,protect
R3239 T4547 T4543 conj ],]
R3240 T4658 T4654 prep under,protect
R3241 T4659 T4660 compound serum,condtions
R3242 T4660 T4658 pobj condtions,under
R3243 T4548 T4539 punct .,S1A
R3244 T4661 T4660 acl treated,condtions
R3245 T4662 T4661 prep with,treated
R3246 T4549 T4556 advmod Recently,validated
R3247 T4663 T4662 pobj zVAD.fmk,with
R3248 T4664 T4663 cc or,zVAD.fmk
R3249 T4665 T4663 conj TNFα,zVAD.fmk
R3250 T4666 T4667 punct (,Fig
R3251 T4667 T4665 appos Fig,TNFα
R3252 T4668 T4651 punct .,was
R3253 T4550 T4556 punct ",",validated
R3254 T4669 T4669 ROOT S1B,S1B
R3255 T4670 T4669 punct ),S1B
R3256 T4671 T4669 cc or,S1B
R3257 T4672 T4674 nmod serum,conditions
R3258 T4551 T4552 poss its,selectivity
R3259 T4673 T4674 amod free,conditions
R3260 T4674 T4669 conj conditions,S1B
R3261 T4552 T4556 nsubjpass selectivity,validated
R3262 T4675 T4674 acl treated,conditions
R3263 T4676 T4675 prep with,treated
R3264 T4677 T4676 pobj bFGF/zVAD,with
R3265 T4553 T4556 aux has,validated
R3266 T4678 T4669 punct .,S1B
R3267 T4679 T4679 ROOT fmk,fmk
R3268 T4680 T4681 punct (,Fig
R3269 T4681 T4679 appos Fig,fmk
R3270 T4554 T4556 auxpass been,validated
R3271 T4682 T4683 punct .,S1C
R3272 T4555 T4556 advmod further,validated
R3273 T4556 T4556 ROOT validated,validated
R3274 T4557 T4556 prep against,validated
R3275 T4683 T4683 ROOT S1C,S1C
R3276 T4558 T4559 det a,panel
R3277 T4684 T4683 punct ),S1C
R3278 T4685 T4679 punct .,fmk
R3279 T4559 T4557 pobj panel,against
R3280 T4686 T4687 nsubj This,confirms
R3281 T4687 T4687 ROOT confirms,confirms
R3282 T4688 T4691 mark that,is
R3283 T4689 T4690 nummod RIP1,kinase
R3284 T4560 T4559 prep of,panel
R3285 T4690 T4691 nsubj kinase,is
R3286 T4691 T4687 ccomp is,confirms
R3287 T4692 T4691 acomp responsible,is
R3288 T4561 T4563 amod more,400
R3289 T4693 T4692 prep for,responsible
R3290 T4694 T4693 pobj necroptosis,for
R3291 T4562 T4563 quantmod than,400
R3292 T4695 T4691 prep in,is
R3293 T4696 T4697 nummod L929,cells
R3294 T4697 T4695 pobj cells,in
R3295 T4563 T4567 quantmod 400,15
R3296 T4698 T4697 prep under,cells
R3297 T4699 T4700 det both,serum
R3298 T4700 T4698 pobj serum,under
R3299 T4701 T4700 cc and,serum
R3300 T4702 T4704 nmod serum,conditions
R3301 T4564 T4565 amod human,kinases
R3302 T4565 T4566 compound kinases,[
R3303 T4703 T4704 amod free,conditions
R3304 T4566 T4567 quantmod [,15
R3305 T4567 T4560 pobj 15,of
R3306 T4704 T4700 conj conditions,serum
R3307 T4568 T4559 appos ],panel
R3308 T4705 T4687 punct .,confirms
R3311 T4569 T4556 punct .,validated
R3314 T4570 T4571 det This,inhibitor
R3317 T4571 T4573 nsubj inhibitor,blocked
R3320 T4572 T4573 advmod efficiently,blocked
R3323 T4573 T4573 ROOT blocked,blocked
R3327 T4574 T4573 dobj growth,blocked
R3328 T4575 T4574 appos factor/zVAD,growth
R3329 T4576 T4573 punct .,blocked
R3332 T4577 T4578 amod fmk-induced,necroptosis
R3336 T4578 T4578 ROOT necroptosis,necroptosis
R3340 T4579 T4578 prep under,necroptosis
R3343 T4580 T4579 pobj serum,under
R3347 T4581 T4582 amod free,conditions
R3354 T4582 T4578 appos conditions,necroptosis
R3358 T4583 T4582 prep in,conditions
R3362 T4584 T4585 compound L929,cells
R3367 T4585 T4583 pobj cells,in

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T4129 887-898 Protein denotes RIP1 kinase
T4128 862-865 Protein denotes S1C
T4127 857-860 Protein denotes Fig
T4126 842-855 Protein denotes bFGF/zVAD.fmk
T4125 794-802 Protein denotes Fig. S1B
T4124 788-792 Protein denotes TNFα
T4123 776-784 Protein denotes zVAD.fmk
T4122 696-702 Protein denotes Nec-1i
T4121 641-645 Negative_regulation denotes loss
T4120 649-660 Protein denotes RIP1 kinase
T4119 566-569 Protein denotes S1A
T4118 561-564 Protein denotes Fig
T4117 503-507 Protein denotes RIP1
T4116 287-294 Negative_regulation denotes blocked
T4115 402-406 Protein denotes TNFα
T4114 389-397 Protein denotes zVAD.fmk
T4113 90-99 Negative_regulation denotes inhibitor
T4112 137-140 Protein denotes S1A
T4111 132-135 Protein denotes Fig
T4110 103-114 Protein denotes RIP1 kinase
R2756 T4110 T4113 themeOf RIP1 kinase,inhibitor
R2757 T4114 T4116 themeOf zVAD.fmk,blocked
R2758 T4120 T4121 themeOf RIP1 kinase,loss

test3

Id Subject Object Predicate Lexical cue
T2913 649-653 Protein denotes RIP1
T2912 503-507 Protein denotes RIP1
T2911 402-406 Protein denotes TNFα
T2910 103-107 Protein denotes RIP1
T2947 887-891 Protein denotes RIP1
T2946 842-846 Protein denotes bFGF
T2945 788-792 Protein denotes TNFα
T2944 649-653 Protein denotes RIP1
T2943 503-507 Protein denotes RIP1
T2942 407-414 Positive_regulation denotes induced
T2941 402-406 Protein denotes TNFα
T2940 103-107 Protein denotes RIP1
T2916 887-891 Protein denotes RIP1
T2915 842-846 Protein denotes bFGF
T2914 788-792 Protein denotes TNFα