PMC:3585731 / 48894-49207 JSONTXT

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    testone

    {"project":"testone","denotations":[{"id":"T20803","span":{"begin":180,"end":190},"obj":"Gene_expression"},{"id":"T20760","span":{"begin":175,"end":179},"obj":"Protein"},{"id":"T20759","span":{"begin":95,"end":104},"obj":"Protein"},{"id":"T20758","span":{"begin":86,"end":90},"obj":"Protein"},{"id":"T20757","span":{"begin":60,"end":64},"obj":"Protein"},{"id":"T20756","span":{"begin":55,"end":59},"obj":"Protein"}],"relations":[{"id":"R13923","pred":"themeOf","subj":"T20760","obj":"T20803"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    2_test

    {"project":"2_test","denotations":[{"id":"23469174-21804564-90505481","span":{"begin":305,"end":306},"obj":"21804564"},{"id":"23469174-21921917-90505482","span":{"begin":310,"end":311},"obj":"21921917"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    pmc-enju-pas

    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recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T21083","span":{"begin":55,"end":59},"obj":"Protein"},{"id":"T21087","span":{"begin":175,"end":179},"obj":"Protein"},{"id":"T21086","span":{"begin":95,"end":104},"obj":"Protein"},{"id":"T21085","span":{"begin":86,"end":90},"obj":"Protein"},{"id":"T21084","span":{"begin":60,"end":64},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T22945","span":{"begin":175,"end":179},"obj":"http://www.uniprot.org/uniprot/P01375"},{"id":"T22931","span":{"begin":55,"end":59},"obj":"http://www.uniprot.org/uniprot/Q13546"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    UBERON-AE

    {"project":"UBERON-AE","denotations":[{"id":"T20932","span":{"begin":224,"end":234},"obj":"http://purl.obolibrary.org/obo/UBERON_0000160"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T21263","span":{"begin":209,"end":234},"obj":"http://purl.obolibrary.org/obo/GO_0048565"},{"id":"T21262","span":{"begin":209,"end":220},"obj":"http://purl.obolibrary.org/obo/GO_0032502"},{"id":"T21261","span":{"begin":65,"end":82},"obj":"http://purl.obolibrary.org/obo/GO_0016301"},{"id":"T21257","span":{"begin":235,"end":247},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T21154","span":{"begin":159,"end":170},"obj":"http://purl.obolibrary.org/obo/GO_0097528"},{"id":"T21130","span":{"begin":159,"end":170},"obj":"http://purl.obolibrary.org/obo/GO_0070266"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    GO-MF

    {"project":"GO-MF","denotations":[{"id":"T21277","span":{"begin":65,"end":82},"obj":"http://purl.obolibrary.org/obo/GO_0016301"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T21286","span":{"begin":119,"end":124},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    sentences

    {"project":"sentences","denotations":[{"id":"T20979","span":{"begin":0,"end":313},"obj":"Sentence"},{"id":"T304","span":{"begin":0,"end":313},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    ICD10

    {"project":"ICD10","denotations":[{"id":"T21264","span":{"begin":288,"end":303},"obj":"http://purl.bioontology.org/ontology/ICD10/K50.9"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    simple1

    {"project":"simple1","denotations":[{"id":"T21339","span":{"begin":175,"end":179},"obj":"Protein"},{"id":"T21338","span":{"begin":95,"end":104},"obj":"Protein"},{"id":"T21337","span":{"begin":86,"end":90},"obj":"Protein"},{"id":"T21336","span":{"begin":60,"end":64},"obj":"Protein"},{"id":"T21335","span":{"begin":55,"end":59},"obj":"Protein"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T22812","span":{"begin":34,"end":38},"obj":"Negative_regulation"},{"id":"T22811","span":{"begin":180,"end":190},"obj":"Gene_expression"},{"id":"T22810","span":{"begin":42,"end":49},"obj":"Regulation"},{"id":"T22786","span":{"begin":175,"end":179},"obj":"Protein"},{"id":"T22785","span":{"begin":95,"end":104},"obj":"Protein"},{"id":"T22784","span":{"begin":86,"end":90},"obj":"Protein"},{"id":"T22783","span":{"begin":60,"end":64},"obj":"Protein"},{"id":"T22782","span":{"begin":55,"end":59},"obj":"Protein"}],"relations":[{"id":"R15393","pred":"themeOf","subj":"T22782","obj":"T22810"},{"id":"R15394","pred":"themeOf","subj":"T22783","obj":"T22812"},{"id":"R15395","pred":"themeOf","subj":"T22783","obj":"T22810"},{"id":"R15396","pred":"themeOf","subj":"T22786","obj":"T22811"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T23117","span":{"begin":175,"end":179},"obj":"Protein"},{"id":"T23116","span":{"begin":95,"end":104},"obj":"Protein"},{"id":"T23115","span":{"begin":86,"end":90},"obj":"Protein"},{"id":"T23114","span":{"begin":60,"end":64},"obj":"Protein"},{"id":"T23113","span":{"begin":55,"end":59},"obj":"Protein"},{"id":"T23142","span":{"begin":180,"end":190},"obj":"Gene_expression"},{"id":"T23141","span":{"begin":34,"end":38},"obj":"Negative_regulation"}],"relations":[{"id":"R15470","pred":"themeOf","subj":"T23114","obj":"T23141"},{"id":"R15471","pred":"themeOf","subj":"T23117","obj":"T23142"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    DLUT931

    {"project":"DLUT931","denotations":[{"id":"T23021","span":{"begin":180,"end":190},"obj":"Gene_expression"},{"id":"T23020","span":{"begin":34,"end":38},"obj":"Negative_regulation"},{"id":"T22987","span":{"begin":175,"end":179},"obj":"Protein"},{"id":"T22986","span":{"begin":95,"end":104},"obj":"Protein"},{"id":"T22985","span":{"begin":86,"end":90},"obj":"Protein"},{"id":"T22984","span":{"begin":60,"end":64},"obj":"Protein"},{"id":"T22983","span":{"begin":55,"end":59},"obj":"Protein"}],"relations":[{"id":"R15429","pred":"themeOf","subj":"T22987","obj":"T23021"},{"id":"R15427","pred":"themeOf","subj":"T22985","obj":"T23020"},{"id":"R15428","pred":"themeOf","subj":"T22986","obj":"T23020"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    bionlp-st-ge-2016-test-ihmc

    {"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T23563","span":{"begin":251,"end":255},"obj":"Protein"},{"id":"T23562","span":{"begin":95,"end":124},"obj":"Protein"},{"id":"T23548","span":{"begin":55,"end":124},"obj":"Protein"},{"id":"T23540","span":{"begin":86,"end":90},"obj":"Protein"},{"id":"T23523","span":{"begin":108,"end":124},"obj":"Entity"},{"id":"T23480","span":{"begin":175,"end":179},"obj":"Protein"},{"id":"T23475","span":{"begin":65,"end":71},"obj":"Protein"},{"id":"T23653","span":{"begin":95,"end":125},"obj":"Localization"}],"relations":[{"id":"R15654","pred":"locationOf","subj":"T23523","obj":"T23653"},{"id":"R15668","pred":"themeOf","subj":"T23562","obj":"T23653"}],"text":"Two recent papers showed that the loss of control over RIP1/RIP3 kinase activities by FADD and caspase-8 in epithelial cells unleashes a feed forward cycle of necroptosis and TNFα production, resulting in the development of intestinal inflammation in mice and, possibly, in patients with Crohn’s disease [4], [5]."}

    bionlp-st-ge-2016-spacy-parsed

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