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PMC:3585731 / 41618-42881 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T20776 979-994 Phosphorylation denotes phosphorylation
T20775 890-905 Phosphorylation denotes phosphorylation
T20774 870-878 Positive_regulation denotes required
T20773 705-715 Gene_expression denotes expression
T20772 597-607 Gene_expression denotes Expression
T20771 576-588 Localization denotes localization
T20770 547-552 Positive_regulation denotes leads
T20769 520-527 Positive_regulation denotes induced
T20768 440-455 Phosphorylation denotes phosphorylation
T20767 190-205 Phosphorylation denotes phosphorylation
T20766 174-182 Positive_regulation denotes increase
T20731 839-843 Protein denotes RIP1
T20730 813-817 Protein denotes TNFα
T20729 719-726 Protein denotes Myr-Akt
T20728 651-658 Protein denotes Myr-Akt
T20727 376-380 Protein denotes TNFα
T20726 249-253 Protein denotes RIP1
T20725 105-109 Protein denotes RIP1
R13909 T20728 T20772 themeOf Myr-Akt,Expression
R13910 T20729 T20773 themeOf Myr-Akt,expression
R13911 T20731 T20774 causeOf RIP1,required
R13925 T20767 T20766 themeOf phosphorylation,increase
R13926 T20771 T20770 themeOf localization,leads
R13927 T20775 T20774 themeOf phosphorylation,required

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T21541 1257-1262 NN denotes death
T21540 1252-1256 NN denotes cell
T21539 1249-1251 IN denotes of
T21538 1244-1248 NN denotes form
T21537 1239-1243 DT denotes this
T21536 1236-1238 IN denotes of
T21535 1227-1235 NN denotes mediator
T21534 1223-1226 JJ denotes new
T21533 1221-1222 DT denotes a
T21532 1209-1220 VB denotes identifying
T21531 1201-1208 RB denotes thereby
T21530 1199-1200 -COMMA- denotes ,
T21529 1188-1199 NN denotes necroptosis
T21528 1185-1187 TO denotes to
T21527 1173-1184 VB denotes contributes
T21526 1166-1172 NN denotes mTORC1
T21525 1163-1165 IN denotes of
T21524 1152-1162 RB denotes downstream
T21523 1144-1151 NN denotes pathway
T21522 1135-1143 NN denotes effector
T21521 1131-1134 NN denotes Akt
T21520 1127-1130 DT denotes the
T21519 1122-1126 IN denotes that
T21518 1115-1121 VB denotes reveal
T21517 1110-1114 NN denotes data
T21516 1106-1109 PRP-DOLLAR- denotes our
T21515 1102-1105 CC denotes and
T21514 1096-1101 NN denotes cells
T21513 1091-1095 NN denotes L929
T21512 1088-1090 IN denotes in
T21511 1077-1087 NN denotes substrates
T21510 1071-1076 VB denotes known
T21509 1068-1070 IN denotes of
T21508 1061-1067 NN denotes number
T21507 1059-1060 DT denotes a
T21506 1051-1058 IN denotes towards
T21505 1042-1050 NN denotes activity
T21504 1038-1041 PRP-DOLLAR- denotes its
T21503 1029-1037 VB denotes increase
T21502 1026-1028 TO denotes to
T21501 1015-1025 JJ denotes sufficient
T21500 1012-1014 VB denotes is
T21499 1008-1011 NN denotes Akt
T21498 1005-1007 IN denotes of
T21497 998-1004 NN denotes Thr308
T21496 995-997 IN denotes of
T21495 979-994 NN denotes phosphorylation
T21494 967-978 JJ denotes Necroptotic
T21493 956-965 NN denotes signaling
T21492 944-955 JJ denotes necroptotic
T21491 940-943 IN denotes for
T21490 931-939 VB denotes required
T21489 928-930 VB denotes is
T21488 923-927 NN denotes turn
T21487 920-922 IN denotes in
T21486 914-919 WDT denotes which
T21485 912-913 -COMMA- denotes ,
T21484 909-912 NN denotes Akt
T21483 906-908 IN denotes of
T21482 890-905 NN denotes phosphorylation
T21481 883-889 NN denotes Thr308
T21480 879-882 IN denotes for
T21479 870-878 VB denotes required
T21478 867-869 VB denotes is
T21477 861-866 NN denotes input
T21476 844-860 JJ denotes kinase-dependent
T21475 839-843 NN denotes RIP1
T21474 837-838 -COMMA- denotes ,
T21473 831-837 JJ denotes second
T21472 829-830 DT denotes A
T21471 818-827 NN denotes synthesis
T21470 813-817 NN denotes TNFα
T21469 809-812 CC denotes and
T21468 805-808 NN denotes JNK
T21467 802-804 IN denotes of
T21466 791-801 NN denotes activation
T21464 778-780 CC denotes or
T21463 766-777 NN denotes necroptosis
T21462 763-765 IN denotes of
T21461 753-762 NN denotes induction
T21460 749-752 DT denotes the
T21459 745-748 IN denotes for
T21458 734-744 JJ denotes sufficient
T21457 730-733 RB denotes not
T21456 727-729 VB denotes is
T21455 719-726 NN denotes Myr-Akt
T21454 716-718 IN denotes of
T21453 705-715 NN denotes expression
T21452 703-704 -COMMA- denotes ,
T21451 699-703 NN denotes time
T21450 694-698 JJ denotes same
T21449 690-693 DT denotes the
T21448 687-689 IN denotes At
T21447 674-685 NN denotes requirement
T21446 669-673 DT denotes this
T21445 659-668 VB denotes overcomes
T21444 651-658 NN denotes Myr-Akt
T21443 633-650 JJ denotes membrane-targeted
T21442 626-632 JJ denotes active
T21441 611-625 RB denotes constitutively
T21440 608-610 IN denotes of
T21439 597-607 NNP denotes Expression
T21438 592-596 NNP denotes Akt.
T21437 589-591 IN denotes of
T21436 576-588 NN denotes localization
T21435 567-575 NN denotes membrane
T21434 560-566 NN denotes plasma
T21433 556-559 DT denotes the
T21432 553-555 TO denotes to
T21431 547-552 VB denotes leads
T21430 545-546 -COMMA- denotes ,
T21429 538-545 NN denotes factors
T21428 531-537 NN denotes growth
T21427 528-530 IN denotes by
T21426 520-527 VB denotes induced
T21425 517-519 VB denotes is
T21424 511-516 WDT denotes which
T21423 509-510 -COMMA- denotes ,
T21422 504-509 NN denotes input
T21421 498-503 JJ denotes first
T21420 494-497 DT denotes The
T21419 485-492 NN denotes signals
T21418 476-484 JJ denotes distinct
T21417 472-475 CD denotes two
T21416 463-471 VB denotes requires
T21415 459-462 NN denotes Akt
T21414 456-458 IN denotes of
T21413 440-455 NN denotes phosphorylation
T21412 438-439 -COMMA- denotes ,
T21411 433-438 NN denotes model
T21410 429-432 PRP-DOLLAR- denotes our
T21409 426-428 TO denotes to
T21408 416-425 VB denotes According
T21407 409-414 NN denotes death
T21406 404-408 NN denotes cell
T21405 395-403 JJ denotes eventual
T21404 391-394 CC denotes and
T21403 381-390 NN denotes synthesis
T21402 376-380 NN denotes TNFα
T21401 366-375 JJ denotes autocrine
T21400 364-365 -COMMA- denotes ,
T21399 354-364 NN denotes activation
T21398 350-353 NN denotes JNK
T21397 340-349 VB denotes including
T21396 338-339 -COMMA- denotes ,
T21395 333-338 NN denotes cells
T21394 328-332 NN denotes L929
T21393 325-327 IN denotes in
T21392 313-324 NN denotes necroptosis
T21391 306-312 IN denotes during
T21390 299-305 NN denotes events
T21389 289-298 NN denotes execution
T21388 285-288 CC denotes and
T21387 275-284 NN denotes signaling
T21386 264-274 JJ denotes downstream
T21385 261-263 TO denotes to
T21384 254-260 NN denotes kinase
T21383 249-253 NN denotes RIP1
T21382 238-248 VB denotes connecting
T21381 233-237 NN denotes link
T21380 231-232 DT denotes a
T21379 222-230 VB denotes provides
T21378 217-221 DT denotes This
T21377 209-215 NN denotes Thr308
T21376 206-208 IN denotes on
T21375 190-205 NN denotes phosphorylation
T21374 186-189 NN denotes Akt
T21373 183-185 IN denotes in
T21372 174-182 NN denotes increase
T21371 164-173 JJ denotes selective
T21370 162-163 DT denotes a
T21369 152-161 VB denotes promoting
T21368 144-151 IN denotes through
T21367 135-143 NN denotes activity
T21366 131-134 PRP-DOLLAR- denotes its
T21365 124-130 VB denotes exerts
T21364 118-123 WDT denotes which
T21363 116-117 -COMMA- denotes ,
T21362 110-116 NN denotes kinase
T21361 105-109 NN denotes RIP1
T21360 100-104 IN denotes from
T21359 89-99 RB denotes downstream
T21358 79-88 NN denotes signaling
T21357 75-78 DT denotes the
T21356 72-74 IN denotes in
T21355 64-71 VB denotes engaged
T21354 51-63 RB denotes specifically
T21353 48-50 VB denotes is
T21352 41-47 NN denotes kinase
T21351 37-40 NN denotes Akt
T21350 32-36 IN denotes that
T21349 24-31 VB denotes suggest
T21348 16-23 NN denotes results
T21347 12-15 PRP-DOLLAR- denotes our
T21346 10-11 -COMMA- denotes ,
T21345 0-10 RB denotes Altogether
T21465 781-790 JJ denotes efficient
R13990 T21348 T21347 arg1Of results,our
R13991 T21348 T21349 arg1Of results,suggest
R13992 T21349 T21345 arg1Of suggest,Altogether
R13993 T21349 T21346 arg1Of suggest,","
R13994 T21352 T21351 arg1Of kinase,Akt
R13995 T21352 T21353 arg1Of kinase,is
R13996 T21352 T21355 arg2Of kinase,engaged
R13997 T21355 T21349 arg2Of engaged,suggest
R13998 T21355 T21350 arg1Of engaged,that
R13999 T21355 T21353 arg2Of engaged,is
R14000 T21355 T21354 arg1Of engaged,specifically
R14001 T21355 T21356 arg1Of engaged,in
R14002 T21355 T21360 arg1Of engaged,from
R14003 T21358 T21356 arg2Of signaling,in
R14004 T21358 T21357 arg1Of signaling,the
R14005 T21360 T21359 arg1Of from,downstream
R14006 T21362 T21360 arg2Of kinase,from
R14007 T21362 T21361 arg1Of kinase,RIP1
R14008 T21362 T21363 arg1Of kinase,","
R14009 T21362 T21364 arg1Of kinase,which
R14010 T21362 T21365 arg1Of kinase,exerts
R14011 T21365 T21368 arg1Of exerts,through
R14012 T21367 T21365 arg2Of activity,exerts
R14013 T21367 T21366 arg1Of activity,its
R14014 T21369 T21368 arg2Of promoting,through
R14015 T21372 T21369 arg2Of increase,promoting
R14016 T21372 T21370 arg1Of increase,a
R14017 T21372 T21371 arg1Of increase,selective
R14018 T21372 T21373 arg1Of increase,in
R14019 T21372 T21376 arg1Of increase,on
R14020 T21375 T21373 arg2Of phosphorylation,in
R14021 T21375 T21374 arg1Of phosphorylation,Akt
R14022 T21377 T21376 arg2Of Thr308,on
R14023 T21378 T21379 arg1Of This,provides
R14024 T21381 T21379 arg2Of link,provides
R14025 T21381 T21380 arg1Of link,a
R14026 T21381 T21382 arg1Of link,connecting
R14027 T21382 T21385 arg1Of connecting,to
R14028 T21382 T21391 arg1Of connecting,during
R14029 T21384 T21382 arg2Of kinase,connecting
R14030 T21384 T21383 arg1Of kinase,RIP1
R14031 T21387 T21388 arg1Of signaling,and
R14032 T21389 T21388 arg2Of execution,and
R14033 T21390 T21385 arg2Of events,to
R14034 T21390 T21386 arg1Of events,downstream
R14035 T21390 T21387 arg1Of events,signaling
R14036 T21390 T21389 arg1Of events,execution
R14037 T21392 T21391 arg2Of necroptosis,during
R14038 T21392 T21393 arg1Of necroptosis,in
R14039 T21395 T21393 arg2Of cells,in
R14040 T21395 T21394 arg1Of cells,L929
R14041 T21395 T21396 arg1Of cells,","
R14042 T21395 T21397 arg1Of cells,including
R14043 T21399 T21398 arg1Of activation,JNK
R14044 T21399 T21400 arg1Of activation,","
R14045 T21400 T21404 arg1Of ",",and
R14046 T21403 T21400 arg2Of synthesis,","
R14047 T21403 T21401 arg1Of synthesis,autocrine
R14048 T21403 T21402 arg1Of synthesis,TNFα
R14049 T21404 T21397 arg2Of and,including
R14050 T21407 T21404 arg2Of death,and
R14051 T21407 T21405 arg1Of death,eventual
R14052 T21407 T21406 arg1Of death,cell
R14053 T21409 T21408 arg2Of to,According
R14054 T21411 T21409 arg2Of model,to
R14055 T21411 T21410 arg1Of model,our
R14056 T21413 T21414 arg1Of phosphorylation,of
R14057 T21413 T21416 arg1Of phosphorylation,requires
R14058 T21415 T21414 arg2Of Akt,of
R14059 T21416 T21408 arg1Of requires,According
R14060 T21416 T21412 arg1Of requires,","
R14061 T21419 T21416 arg2Of signals,requires
R14062 T21419 T21417 arg1Of signals,two
R14063 T21419 T21418 arg1Of signals,distinct
R14064 T21422 T21420 arg1Of input,The
R14065 T21422 T21421 arg1Of input,first
R14066 T21422 T21423 arg1Of input,","
R14067 T21422 T21424 arg1Of input,which
R14068 T21422 T21425 arg1Of input,is
R14069 T21422 T21426 arg2Of input,induced
R14070 T21422 T21431 arg1Of input,leads
R14071 T21422 T21445 arg1Of input,overcomes
R14072 T21426 T21425 arg2Of induced,is
R14073 T21426 T21430 arg1Of induced,","
R14074 T21429 T21426 arg1Of factors,induced
R14075 T21429 T21427 arg2Of factors,by
R14076 T21429 T21428 arg1Of factors,growth
R14077 T21431 T21430 arg2Of leads,","
R14078 T21431 T21432 arg1Of leads,to
R14079 T21436 T21432 arg2Of localization,to
R14080 T21436 T21433 arg1Of localization,the
R14081 T21436 T21434 arg1Of localization,plasma
R14082 T21436 T21435 arg1Of localization,membrane
R14083 T21436 T21437 arg1Of localization,of
R14084 T21439 T21437 arg2Of Expression,of
R14085 T21439 T21438 arg1Of Expression,Akt.
R14086 T21439 T21440 arg1Of Expression,of
R14087 T21444 T21440 arg2Of Myr-Akt,of
R14088 T21444 T21441 arg1Of Myr-Akt,constitutively
R14089 T21444 T21442 arg1Of Myr-Akt,active
R14090 T21444 T21443 arg1Of Myr-Akt,membrane-targeted
R14091 T21447 T21445 arg2Of requirement,overcomes
R14092 T21447 T21446 arg1Of requirement,this
R14093 T21451 T21448 arg2Of time,At
R14094 T21451 T21449 arg1Of time,the
R14095 T21451 T21450 arg1Of time,same
R14096 T21453 T21454 arg1Of expression,of
R14097 T21453 T21456 arg1Of expression,is
R14098 T21453 T21458 arg1Of expression,sufficient
R14099 T21455 T21454 arg2Of Myr-Akt,of
R14100 T21456 T21448 arg1Of is,At
R14101 T21456 T21452 arg1Of is,","
R14102 T21456 T21457 arg1Of is,not
R14103 T21458 T21456 arg2Of sufficient,is
R14104 T21458 T21459 arg1Of sufficient,for
R14105 T21461 T21459 arg2Of induction,for
R14106 T21461 T21460 arg1Of induction,the
R14107 T21461 T21462 arg1Of induction,of
R14108 T21463 T21464 arg1Of necroptosis,or
R14109 T21465 T21464 arg2Of efficient,or
R14110 T21466 T21462 arg2Of activation,of
R14111 T21466 T21463 arg1Of activation,necroptosis
R14112 T21466 T21465 arg1Of activation,efficient
R14113 T21466 T21467 arg1Of activation,of
R14114 T21468 T21469 arg1Of JNK,and
R14115 T21469 T21467 arg2Of and,of
R14116 T21471 T21469 arg2Of synthesis,and
R14117 T21471 T21470 arg1Of synthesis,TNFα
R14118 T21473 T21474 arg1Of second,","
R14119 T21476 T21474 arg2Of kinase-dependent,","
R14120 T21476 T21475 arg1Of kinase-dependent,RIP1
R14121 T21477 T21472 arg1Of input,A
R14122 T21477 T21473 arg1Of input,second
R14123 T21477 T21476 arg1Of input,kinase-dependent
R14124 T21477 T21478 arg1Of input,is
R14125 T21477 T21479 arg2Of input,required
R14126 T21479 T21478 arg2Of required,is
R14127 T21479 T21480 arg1Of required,for
R14128 T21482 T21480 arg2Of phosphorylation,for
R14129 T21482 T21481 arg1Of phosphorylation,Thr308
R14130 T21482 T21483 arg1Of phosphorylation,of
R14131 T21484 T21483 arg2Of Akt,of
R14132 T21484 T21485 arg1Of Akt,","
R14133 T21484 T21486 arg1Of Akt,which
R14134 T21484 T21489 arg1Of Akt,is
R14135 T21484 T21490 arg2Of Akt,required
R14136 T21488 T21487 arg2Of turn,in
R14137 T21490 T21487 arg1Of required,in
R14138 T21490 T21489 arg2Of required,is
R14139 T21490 T21491 arg1Of required,for
R14140 T21493 T21491 arg2Of signaling,for
R14141 T21493 T21492 arg1Of signaling,necroptotic
R14142 T21495 T21494 arg1Of phosphorylation,Necroptotic
R14143 T21495 T21496 arg1Of phosphorylation,of
R14144 T21495 T21498 arg1Of phosphorylation,of
R14145 T21495 T21500 arg1Of phosphorylation,is
R14146 T21495 T21501 arg1Of phosphorylation,sufficient
R14147 T21497 T21496 arg2Of Thr308,of
R14148 T21499 T21498 arg2Of Akt,of
R14149 T21500 T21515 arg1Of is,and
R14150 T21501 T21500 arg2Of sufficient,is
R14151 T21503 T21501 arg2Of increase,sufficient
R14152 T21503 T21502 arg1Of increase,to
R14153 T21503 T21506 arg1Of increase,towards
R14154 T21505 T21503 arg2Of activity,increase
R14155 T21505 T21504 arg1Of activity,its
R14156 T21508 T21506 arg2Of number,towards
R14157 T21508 T21507 arg1Of number,a
R14158 T21508 T21509 arg1Of number,of
R14159 T21511 T21509 arg2Of substrates,of
R14160 T21511 T21510 arg2Of substrates,known
R14161 T21511 T21512 arg1Of substrates,in
R14162 T21514 T21512 arg2Of cells,in
R14163 T21514 T21513 arg1Of cells,L929
R14164 T21517 T21516 arg1Of data,our
R14165 T21517 T21518 arg1Of data,reveal
R14166 T21518 T21515 arg2Of reveal,and
R14167 T21523 T21520 arg1Of pathway,the
R14168 T21523 T21521 arg1Of pathway,Akt
R14169 T21523 T21522 arg1Of pathway,effector
R14170 T21523 T21524 arg1Of pathway,downstream
R14171 T21523 T21527 arg1Of pathway,contributes
R14172 T21524 T21525 arg1Of downstream,of
R14173 T21526 T21525 arg2Of mTORC1,of
R14174 T21527 T21518 arg2Of contributes,reveal
R14175 T21527 T21519 arg1Of contributes,that
R14176 T21527 T21528 arg1Of contributes,to
R14177 T21527 T21530 arg1Of contributes,","
R14178 T21527 T21532 modOf contributes,identifying
R14179 T21529 T21528 arg2Of necroptosis,to
R14180 T21532 T21531 arg1Of identifying,thereby
R14181 T21535 T21532 arg2Of mediator,identifying
R14182 T21535 T21533 arg1Of mediator,a
R14183 T21535 T21534 arg1Of mediator,new
R14184 T21535 T21536 arg1Of mediator,of
R14185 T21538 T21536 arg2Of form,of
R14186 T21538 T21537 arg1Of form,this
R14187 T21538 T21539 arg1Of form,of
R14188 T21541 T21539 arg2Of death,of
R14189 T21541 T21540 arg1Of death,cell

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T21058 839-843 Protein denotes RIP1
T21057 813-817 Protein denotes TNFα
T21056 719-726 Protein denotes Myr-Akt
T21055 651-658 Protein denotes Myr-Akt
T21054 376-380 Protein denotes TNFα
T21053 249-253 Protein denotes RIP1
T21052 105-109 Protein denotes RIP1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T22936 813-817 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T22935 376-380 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T22920 839-843 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T22919 249-253 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T22918 105-109 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T22858 1131-1134 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22857 1008-1011 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22856 909-912 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22855 723-726 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22854 655-658 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22824 1131-1134 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22823 1008-1011 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22822 909-912 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22821 723-726 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22820 655-658 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22819 592-595 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22818 459-462 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22817 186-189 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22816 37-40 http://www.uniprot.org/uniprot/P31749 denotes Akt
T22888 655-658 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T22887 592-595 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T22886 459-462 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T22885 186-189 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T22884 37-40 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T22853 592-595 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22852 459-462 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22851 186-189 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22850 37-40 http://www.uniprot.org/uniprot/P31751 denotes Akt
T22892 1131-1134 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T22891 1008-1011 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T22890 909-912 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T22889 723-726 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt

GO-BP

Id Subject Object Predicate Lexical cue
T21200 576-588 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T21199 567-588 http://purl.obolibrary.org/obo/GO_0051668 denotes membrane localization
T21198 560-588 http://purl.obolibrary.org/obo/GO_0072659 denotes plasma membrane localization
T21197 560-588 http://purl.obolibrary.org/obo/GO_0044856 denotes plasma membrane localization
T21196 531-537 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T21180 1257-1262 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T21179 409-414 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T21168 1252-1262 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T21167 404-414 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T21163 818-827 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T21162 381-390 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T21157 805-808 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T21156 350-353 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T21138 1188-1199 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T21137 766-777 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T21136 313-324 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T21131 753-777 http://purl.obolibrary.org/obo/GO_0070266 denotes induction of necroptosis
T21114 1188-1199 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T21113 766-777 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T21112 313-324 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T21106 979-994 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T21105 890-905 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T21104 440-455 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T21103 190-205 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T21095 956-965 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T21094 275-284 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T21093 79-88 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling

GO-MF

Id Subject Object Predicate Lexical cue
T21268 805-808 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T21267 350-353 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK

GO-CC

Id Subject Object Predicate Lexical cue
T21293 1166-1172 http://purl.obolibrary.org/obo/GO_0031931 denotes mTORC1
T21291 633-641 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T21290 567-575 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T21288 560-575 http://purl.obolibrary.org/obo/GO_0005886 denotes plasma membrane
T21279 1096-1101 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T21278 333-338 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T20940 967-1263 Sentence denotes Necroptotic phosphorylation of Thr308 of Akt is sufficient to increase its activity towards a number of known substrates in L929 cells and our data reveal that the Akt effector pathway downstream of mTORC1 contributes to necroptosis, thereby identifying a new mediator of this form of cell death.
T20939 829-966 Sentence denotes A second, RIP1 kinase-dependent input is required for Thr308 phosphorylation of Akt, which in turn is required for necroptotic signaling.
T20938 687-828 Sentence denotes At the same time, expression of Myr-Akt is not sufficient for the induction of necroptosis or efficient activation of JNK and TNFα synthesis.
T20937 494-686 Sentence denotes The first input, which is induced by growth factors, leads to the plasma membrane localization of Akt. Expression of constitutively active membrane-targeted Myr-Akt overcomes this requirement.
T20936 416-493 Sentence denotes According to our model, phosphorylation of Akt requires two distinct signals.
T20935 217-415 Sentence denotes This provides a link connecting RIP1 kinase to downstream signaling and execution events during necroptosis in L929 cells, including JNK activation, autocrine TNFα synthesis and eventual cell death.
T20934 0-216 Sentence denotes Altogether, our results suggest that Akt kinase is specifically engaged in the signaling downstream from RIP1 kinase, which exerts its activity through promoting a selective increase in Akt phosphorylation on Thr308.
T258 0-216 Sentence denotes Altogether, our results suggest that Akt kinase is specifically engaged in the signaling downstream from RIP1 kinase, which exerts its activity through promoting a selective increase in Akt phosphorylation on Thr308.
T259 217-415 Sentence denotes This provides a link connecting RIP1 kinase to downstream signaling and execution events during necroptosis in L929 cells, including JNK activation, autocrine TNFα synthesis and eventual cell death.
T260 416-493 Sentence denotes According to our model, phosphorylation of Akt requires two distinct signals.
T261 494-596 Sentence denotes The first input, which is induced by growth factors, leads to the plasma membrane localization of Akt.
T262 597-686 Sentence denotes Expression of constitutively active membrane-targeted Myr-Akt overcomes this requirement.
T263 687-828 Sentence denotes At the same time, expression of Myr-Akt is not sufficient for the induction of necroptosis or efficient activation of JNK and TNFα synthesis.
T264 829-966 Sentence denotes A second, RIP1 kinase-dependent input is required for Thr308 phosphorylation of Akt, which in turn is required for necroptotic signaling.
T265 967-1263 Sentence denotes Necroptotic phosphorylation of Thr308 of Akt is sufficient to increase its activity towards a number of known substrates in L929 cells and our data reveal that the Akt effector pathway downstream of mTORC1 contributes to necroptosis, thereby identifying a new mediator of this form of cell death.

simple1

Id Subject Object Predicate Lexical cue
T21310 839-843 Protein denotes RIP1
T21309 813-817 Protein denotes TNFα
T21308 719-726 Protein denotes Myr-Akt
T21307 651-658 Protein denotes Myr-Akt
T21306 376-380 Protein denotes TNFα
T21305 249-253 Protein denotes RIP1
T21304 105-109 Protein denotes RIP1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T22798 705-715 Gene_expression denotes expression
T22797 734-744 Positive_regulation denotes sufficient
T22796 818-827 Gene_expression denotes synthesis
T22795 791-801 Positive_regulation denotes activation
T22794 597-607 Gene_expression denotes Expression
T22793 633-650 Positive_regulation denotes membrane-targeted
T22792 381-390 Gene_expression denotes synthesis
T22757 839-843 Protein denotes RIP1
T22756 813-817 Protein denotes TNFα
T22755 719-726 Protein denotes Myr-Akt
T22754 651-658 Protein denotes Myr-Akt
T22753 376-380 Protein denotes TNFα
T22752 249-253 Protein denotes RIP1
T22751 105-109 Protein denotes RIP1
R15381 T22753 T22792 themeOf TNFα,synthesis
R15382 T22754 T22794 themeOf Myr-Akt,Expression
R15383 T22754 T22793 themeOf Myr-Akt,membrane-targeted
R15384 T22755 T22798 themeOf Myr-Akt,expression
R15385 T22756 T22796 themeOf TNFα,synthesis
R15399 T22796 T22795 themeOf synthesis,activation
R15400 T22798 T22797 themeOf expression,sufficient

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T23123 381-390 Gene_expression denotes synthesis
T23088 839-843 Protein denotes RIP1
T23087 813-817 Protein denotes TNFα
T23086 719-726 Protein denotes Myr-Akt
T23085 651-658 Protein denotes Myr-Akt
T23084 376-380 Protein denotes TNFα
T23083 249-253 Protein denotes RIP1
T23082 105-109 Protein denotes RIP1
T23129 844-860 Regulation denotes kinase-dependent
T23128 818-827 Gene_expression denotes synthesis
T23127 791-801 Positive_regulation denotes activation
T23126 705-715 Gene_expression denotes expression
T23125 633-650 Binding denotes membrane-targeted
T23124 597-607 Gene_expression denotes Expression
R15457 T23084 T23123 themeOf TNFα,synthesis
R15458 T23085 T23124 themeOf Myr-Akt,Expression
R15459 T23085 T23125 themeOf Myr-Akt,membrane-targeted
R15460 T23086 T23126 themeOf Myr-Akt,expression
R15461 T23087 T23128 themeOf TNFα,synthesis
R15462 T23088 T23129 themeOf RIP1,kinase-dependent
R15475 T23128 T23127 themeOf synthesis,activation

DLUT931

Id Subject Object Predicate Lexical cue
T23001 844-860 Positive_regulation denotes kinase-dependent
T23000 791-801 Positive_regulation denotes activation
T22999 818-827 Gene_expression denotes synthesis
T22998 734-744 Positive_regulation denotes sufficient
T22997 705-715 Gene_expression denotes expression
T22996 633-650 Positive_regulation denotes membrane-targeted
T22995 597-607 Gene_expression denotes Expression
T22994 366-375 Positive_regulation denotes autocrine
T22993 381-390 Gene_expression denotes synthesis
T22958 839-843 Protein denotes RIP1
T22957 813-817 Protein denotes TNFα
T22956 719-726 Protein denotes Myr-Akt
T22955 651-658 Protein denotes Myr-Akt
T22954 376-380 Protein denotes TNFα
T22953 249-253 Protein denotes RIP1
T22952 105-109 Protein denotes RIP1
R15406 T22954 T22993 themeOf TNFα,synthesis
R15433 T22993 T22994 themeOf synthesis,autocrine
R15434 T22995 T22996 themeOf Expression,membrane-targeted
R15435 T22997 T22998 themeOf expression,sufficient
R15436 T22999 T23000 themeOf synthesis,activation
R15407 T22955 T22995 themeOf Myr-Akt,Expression
R15408 T22955 T22996 themeOf Myr-Akt,membrane-targeted
R15409 T22956 T22997 themeOf Myr-Akt,expression
R15410 T22957 T22999 themeOf TNFα,synthesis
R15411 T22958 T23001 themeOf RIP1,kinase-dependent

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T23586 1131-1134 Protein denotes Akt
T23579 1166-1172 Entity denotes mTORC1
T23568 249-260 Protein denotes RIP1 kinase
T23560 839-843 Protein denotes RIP1
T23557 839-860 Protein denotes RIP1 kinase-dependent
T23552 37-40 Protein denotes Akt
T23551 883-889 Entity denotes Thr308
T23541 456-462 Protein denotes of Akt
T23539 206-215 Entity denotes on Thr308
T23535 906-912 Protein denotes of Akt
T23534 366-390 Protein denotes autocrine TNFα synthesis
T23532 626-658 Protein denotes active membrane-targeted Myr-Akt
T23522 716-726 Protein denotes of Myr-Akt
T23521 556-575 Entity denotes the plasma membrane
T23517 37-47 Protein denotes Akt kinase
T23512 805-808 Protein denotes JNK
T23503 589-595 Protein denotes of Akt
T23494 350-353 Protein denotes JNK
T23488 186-189 Protein denotes Akt
T23486 995-1011 Entity denotes of Thr308 of Akt
T23479 813-817 Protein denotes TNFα
T23478 249-253 Protein denotes RIP1
T23476 1008-1011 Protein denotes Akt
T23643 705-726 Gene_expression denotes expression of Myr-Akt
T23642 883-913 Phosphorylation denotes Thr308 phosphorylation of Akt,
T23639 967-1011 Phosphorylation denotes Necroptotic phosphorylation of Thr308 of Akt
T23637 350-364 Positive_regulation denotes JNK activation
T23634 152-215 Positive_regulation denotes promoting a selective increase in Akt phosphorylation on Thr308
T23632 162-215 Positive_regulation denotes a selective increase in Akt phosphorylation on Thr308
T23625 440-462 Phosphorylation denotes phosphorylation of Akt
T23611 633-650 Entity denotes membrane-targeted
T23602 1068-1087 Entity denotes of known substrates
T23601 1127-1151 Entity denotes the Akt effector pathway
T23598 105-109 Protein denotes RIP1
T23597 51-116 Protein denotes specifically engaged in the signaling downstream from RIP1 kinase
R15643 T23476 T23639 themeOf Akt,Necroptotic phosphorylation of Thr308 of Akt
R15645 T23486 T23476 partOf of Thr308 of Akt,Akt
R15646 T23486 T23639 siteOf of Thr308 of Akt,Necroptotic phosphorylation of Thr308 of Akt
R15647 T23494 T23637 themeOf JNK,JNK activation
R15653 T23522 T23643 themeOf of Myr-Akt,expression of Myr-Akt
R15658 T23535 T23642 themeOf of Akt,"Thr308 phosphorylation of Akt,"
R15659 T23541 T23625 themeOf of Akt,phosphorylation of Akt
R15665 T23551 T23535 partOf Thr308,of Akt
R15666 T23551 T23642 siteOf Thr308,"Thr308 phosphorylation of Akt,"
R15681 T23632 T23634 themeOf a selective increase in Akt phosphorylation on Thr308,promoting a selective increase in Akt phosphorylation on Thr308

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T23859 1262-1263 . denotes .
T23858 1257-1262 NN denotes death
T23857 1252-1256 NN denotes cell
T23856 1249-1251 IN denotes of
T23855 1244-1248 NN denotes form
T23854 1239-1243 DT denotes this
T23853 1236-1238 IN denotes of
T23852 1227-1235 NN denotes mediator
T23851 1223-1226 JJ denotes new
T23850 1221-1222 DT denotes a
T23849 1209-1220 VBG denotes identifying
T23848 1201-1208 RB denotes thereby
T23847 1199-1200 , denotes ,
T23846 1188-1199 NN denotes necroptosis
T23845 1185-1187 TO denotes to
T23844 1173-1184 VBZ denotes contributes
T23843 1166-1172 JJ denotes mTORC1
T23842 1163-1165 IN denotes of
T23841 1152-1162 JJ denotes downstream
T23840 1144-1151 NN denotes pathway
T23839 1135-1143 NN denotes effector
T23838 1131-1134 NNP denotes Akt
T23837 1127-1130 DT denotes the
T23836 1122-1126 IN denotes that
T23835 1115-1121 VBP denotes reveal
T23834 1110-1114 NNS denotes data
T23833 1106-1109 PRP$ denotes our
T23832 1102-1105 CC denotes and
T23831 1096-1101 NNS denotes cells
T23830 1091-1095 NNP denotes L929
T23829 1088-1090 IN denotes in
T23828 1077-1087 NNS denotes substrates
T23827 1071-1076 VBN denotes known
T23826 1068-1070 IN denotes of
T23825 1061-1067 NN denotes number
T23824 1059-1060 DT denotes a
T23823 1051-1058 IN denotes towards
T23822 1042-1050 NN denotes activity
T23821 1038-1041 PRP$ denotes its
T23820 1029-1037 VB denotes increase
T23819 1026-1028 TO denotes to
T23818 1015-1025 JJ denotes sufficient
T23817 1012-1014 VBZ denotes is
T23816 1008-1011 NNP denotes Akt
T23815 1005-1007 IN denotes of
T23814 998-1004 CD denotes Thr308
T23813 995-997 IN denotes of
T23812 979-994 NN denotes phosphorylation
T23811 967-978 JJ denotes Necroptotic
T23810 965-966 . denotes .
T23809 956-965 VBG denotes signaling
T23808 944-955 JJ denotes necroptotic
T23807 940-943 IN denotes for
T23806 931-939 VBN denotes required
T23805 928-930 VBZ denotes is
T23804 923-927 NN denotes turn
T23803 920-922 IN denotes in
T23802 914-919 WDT denotes which
T23801 912-913 , denotes ,
T23785 813-817 NNP denotes TNFα
T23784 809-812 CC denotes and
T23783 805-808 NNP denotes JNK
T23782 802-804 IN denotes of
T23781 791-801 NN denotes activation
T23780 781-790 JJ denotes efficient
T23779 778-780 CC denotes or
T23778 766-777 NN denotes necroptosis
T23777 763-765 IN denotes of
T23776 753-762 NN denotes induction
T23775 749-752 DT denotes the
T23774 745-748 IN denotes for
T23773 734-744 JJ denotes sufficient
T23772 730-733 RB denotes not
T23771 727-729 VBZ denotes is
T23770 719-726 NNP denotes Myr-Akt
T23769 716-718 IN denotes of
T23768 705-715 NN denotes expression
T23767 703-704 , denotes ,
T23766 699-703 NN denotes time
T23765 694-698 JJ denotes same
T23764 690-693 DT denotes the
T23763 687-689 IN denotes At
T23762 685-686 . denotes .
T23761 674-685 NN denotes requirement
T23760 669-673 DT denotes this
T23759 659-668 VBZ denotes overcomes
T23758 651-658 NNP denotes Myr-Akt
T23757 633-650 JJ denotes membrane-targeted
T23756 626-632 JJ denotes active
T23755 611-625 RB denotes constitutively
T23754 608-610 IN denotes of
T23753 597-607 NN denotes Expression
T23752 595-596 . denotes .
T23751 592-595 NNP denotes Akt
T23750 589-591 IN denotes of
T23749 576-588 NN denotes localization
T23748 567-575 NN denotes membrane
T23747 560-566 NN denotes plasma
T23746 556-559 DT denotes the
T23745 553-555 TO denotes to
T23744 547-552 VBZ denotes leads
T23743 545-546 , denotes ,
T23742 538-545 NNS denotes factors
T23741 531-537 NN denotes growth
T23740 528-530 IN denotes by
T23739 520-527 VBN denotes induced
T23738 517-519 VBZ denotes is
T23737 511-516 WDT denotes which
T23736 509-510 , denotes ,
T23735 504-509 NN denotes input
T23734 498-503 JJ denotes first
T23733 494-497 DT denotes The
T23732 492-493 . denotes .
T23731 485-492 NNS denotes signals
T23730 476-484 JJ denotes distinct
T23729 472-475 CD denotes two
T23728 463-471 VBZ denotes requires
T23727 459-462 NNP denotes Akt
T23726 456-458 IN denotes of
T23725 440-455 NN denotes phosphorylation
T23724 438-439 , denotes ,
T23723 433-438 NN denotes model
T23722 429-432 PRP$ denotes our
T23721 426-428 TO denotes to
T23720 416-425 VBG denotes According
T23719 414-415 . denotes .
T23718 409-414 NN denotes death
T23717 404-408 NN denotes cell
T23716 395-403 JJ denotes eventual
T23715 391-394 CC denotes and
T23714 381-390 NN denotes synthesis
T23713 376-380 NNP denotes TNFα
T23712 366-375 NN denotes autocrine
T23711 364-365 , denotes ,
T23710 354-364 NN denotes activation
T23709 350-353 NNP denotes JNK
T23708 340-349 VBG denotes including
T23707 338-339 , denotes ,
T23706 333-338 NNS denotes cells
T23705 328-332 CD denotes L929
T23704 325-327 IN denotes in
T23703 313-324 NN denotes necroptosis
T23702 306-312 IN denotes during
T23701 299-305 NNS denotes events
T23700 289-298 NN denotes execution
T23699 285-288 CC denotes and
T23698 275-284 VBG denotes signaling
T23697 264-274 JJ denotes downstream
T23696 261-263 TO denotes to
T23695 254-260 NN denotes kinase
T23694 249-253 CD denotes RIP1
T23693 238-248 VBG denotes connecting
T23692 233-237 NN denotes link
T23691 231-232 DT denotes a
T23690 222-230 VBZ denotes provides
T23689 217-221 DT denotes This
T23688 215-216 . denotes .
T23687 209-215 NNP denotes Thr308
T23686 206-208 IN denotes on
T23685 190-205 NN denotes phosphorylation
T23684 186-189 NNP denotes Akt
T23683 183-185 IN denotes in
T23682 174-182 NN denotes increase
T23681 164-173 JJ denotes selective
T23680 162-163 DT denotes a
T23679 152-161 VBG denotes promoting
T23678 144-151 IN denotes through
T23677 135-143 NN denotes activity
T23676 131-134 PRP$ denotes its
T23675 124-130 VBZ denotes exerts
T23674 118-123 WDT denotes which
T23673 116-117 , denotes ,
T23672 110-116 NN denotes kinase
T23671 105-109 CD denotes RIP1
T23670 100-104 IN denotes from
T23669 89-99 JJ denotes downstream
T23668 79-88 VBG denotes signaling
T23667 75-78 DT denotes the
T23666 72-74 IN denotes in
T23665 64-71 VBN denotes engaged
T23664 51-63 RB denotes specifically
T23663 48-50 VBZ denotes is
T23662 41-47 NN denotes kinase
T23661 37-40 NNP denotes Akt
T23660 32-36 IN denotes that
T23659 24-31 VBP denotes suggest
T23658 16-23 NNS denotes results
T23657 12-15 PRP$ denotes our
T23656 10-11 , denotes ,
T23655 0-10 RB denotes Altogether
T23800 909-912 NNP denotes Akt
T23799 906-908 IN denotes of
T23798 890-905 NN denotes phosphorylation
T23797 883-889 NNP denotes Thr308
T23796 879-882 IN denotes for
T23795 870-878 VBN denotes required
T23794 867-869 VBZ denotes is
T23793 861-866 NN denotes input
T23792 844-860 JJ denotes kinase-dependent
T23791 839-843 JJ denotes RIP1
T23790 837-838 , denotes ,
T23789 831-837 JJ denotes second
T23788 829-830 DT denotes A
T23787 827-828 . denotes .
T23786 818-827 NN denotes synthesis
R15684 T23655 T23659 advmod Altogether,suggest
R15685 T23656 T23659 punct ",",suggest
R15686 T23657 T23658 poss our,results
R15687 T23658 T23659 nsubj results,suggest
R15688 T23659 T23659 ROOT suggest,suggest
R15689 T23660 T23665 mark that,engaged
R15690 T23661 T23662 compound Akt,kinase
R15691 T23662 T23665 nsubjpass kinase,engaged
R15692 T23663 T23665 auxpass is,engaged
R15693 T23664 T23665 advmod specifically,engaged
R15694 T23665 T23659 ccomp engaged,suggest
R15695 T23666 T23665 prep in,engaged
R15696 T23667 T23669 det the,downstream
R15697 T23668 T23669 amod signaling,downstream
R15698 T23669 T23666 pobj downstream,in
R15699 T23670 T23665 prep from,engaged
R15700 T23671 T23672 nummod RIP1,kinase
R15701 T23672 T23670 pobj kinase,from
R15702 T23673 T23672 punct ",",kinase
R15703 T23674 T23675 nsubj which,exerts
R15704 T23675 T23672 relcl exerts,kinase
R15705 T23676 T23677 poss its,activity
R15706 T23677 T23675 dobj activity,exerts
R15707 T23678 T23675 prep through,exerts
R15708 T23679 T23678 pcomp promoting,through
R15709 T23680 T23682 det a,increase
R15710 T23681 T23682 amod selective,increase
R15711 T23682 T23679 dobj increase,promoting
R15712 T23683 T23682 prep in,increase
R15713 T23684 T23685 compound Akt,phosphorylation
R15714 T23685 T23683 pobj phosphorylation,in
R15715 T23686 T23682 prep on,increase
R15716 T23687 T23686 pobj Thr308,on
R15717 T23688 T23659 punct .,suggest
R15718 T23689 T23690 nsubj This,provides
R15719 T23690 T23690 ROOT provides,provides
R15720 T23691 T23692 det a,link
R15721 T23692 T23701 nmod link,events
R15722 T23693 T23692 acl connecting,link
R15723 T23694 T23695 nummod RIP1,kinase
R15724 T23695 T23693 dobj kinase,connecting
R15725 T23696 T23693 prep to,connecting
R15726 T23697 T23698 amod downstream,signaling
R15727 T23698 T23696 pobj signaling,to
R15728 T23699 T23698 cc and,signaling
R15729 T23700 T23701 compound execution,events
R15730 T23701 T23690 dobj events,provides
R15731 T23702 T23690 prep during,provides
R15732 T23703 T23702 pobj necroptosis,during
R15733 T23704 T23703 prep in,necroptosis
R15734 T23705 T23706 nummod L929,cells
R15735 T23706 T23704 pobj cells,in
R15736 T23707 T23703 punct ",",necroptosis
R15737 T23708 T23703 prep including,necroptosis
R15738 T23709 T23710 compound JNK,activation
R15739 T23710 T23708 pobj activation,including
R15740 T23711 T23710 punct ",",activation
R15741 T23712 T23714 compound autocrine,synthesis
R15742 T23713 T23714 compound TNFα,synthesis
R15743 T23714 T23710 conj synthesis,activation
R15744 T23715 T23714 cc and,synthesis
R15745 T23716 T23718 amod eventual,death
R15746 T23717 T23718 compound cell,death
R15747 T23718 T23714 conj death,synthesis
R15748 T23719 T23690 punct .,provides
R15749 T23720 T23728 csubj According,requires
R15750 T23721 T23720 prep to,According
R15751 T23722 T23723 poss our,model
R15752 T23723 T23721 pobj model,to
R15753 T23724 T23723 punct ",",model
R15754 T23725 T23723 conj phosphorylation,model
R15755 T23726 T23723 prep of,model
R15756 T23727 T23726 pobj Akt,of
R15757 T23728 T23728 ROOT requires,requires
R15758 T23729 T23731 nummod two,signals
R15759 T23730 T23731 amod distinct,signals
R15760 T23731 T23728 dobj signals,requires
R15761 T23732 T23728 punct .,requires
R15762 T23733 T23735 det The,input
R15763 T23734 T23735 amod first,input
R15764 T23735 T23744 nsubj input,leads
R15765 T23736 T23735 punct ",",input
R15766 T23737 T23739 nsubjpass which,induced
R15767 T23738 T23739 auxpass is,induced
R15768 T23739 T23735 relcl induced,input
R15769 T23740 T23739 agent by,induced
R15770 T23741 T23742 compound growth,factors
R15771 T23742 T23740 pobj factors,by
R15772 T23743 T23735 punct ",",input
R15773 T23744 T23744 ROOT leads,leads
R15774 T23745 T23744 prep to,leads
R15775 T23746 T23749 det the,localization
R15776 T23747 T23749 amod plasma,localization
R15777 T23748 T23749 compound membrane,localization
R15778 T23749 T23745 pobj localization,to
R15779 T23750 T23749 prep of,localization
R15780 T23751 T23750 pobj Akt,of
R15781 T23752 T23744 punct .,leads
R15782 T23753 T23759 nsubj Expression,overcomes
R15783 T23754 T23753 prep of,Expression
R15784 T23755 T23756 advmod constitutively,active
R15785 T23756 T23758 amod active,Myr-Akt
R15786 T23757 T23758 compound membrane-targeted,Myr-Akt
R15787 T23758 T23754 pobj Myr-Akt,of
R15788 T23759 T23759 ROOT overcomes,overcomes
R15789 T23760 T23761 det this,requirement
R15790 T23761 T23759 dobj requirement,overcomes
R15791 T23762 T23759 punct .,overcomes
R15792 T23763 T23771 prep At,is
R15793 T23764 T23766 det the,time
R15794 T23765 T23766 amod same,time
R15795 T23766 T23763 pobj time,At
R15796 T23767 T23771 punct ",",is
R15797 T23768 T23771 nsubj expression,is
R15798 T23769 T23768 prep of,expression
R15799 T23770 T23769 pobj Myr-Akt,of
R15800 T23771 T23771 ROOT is,is
R15801 T23772 T23771 neg not,is
R15802 T23773 T23771 acomp sufficient,is
R15803 T23774 T23773 prep for,sufficient
R15804 T23775 T23776 det the,induction
R15805 T23776 T23774 pobj induction,for
R15806 T23777 T23776 prep of,induction
R15807 T23778 T23777 pobj necroptosis,of
R15808 T23779 T23778 cc or,necroptosis
R15809 T23780 T23781 amod efficient,activation
R15810 T23781 T23778 conj activation,necroptosis
R15811 T23782 T23781 prep of,activation
R15812 T23783 T23782 pobj JNK,of
R15813 T23784 T23783 cc and,JNK
R15814 T23785 T23786 compound TNFα,synthesis
R15815 T23786 T23781 conj synthesis,activation
R15816 T23787 T23771 punct .,is
R15817 T23788 T23793 det A,input
R15818 T23789 T23793 amod second,input
R15819 T23790 T23793 punct ",",input
R15820 T23791 T23793 amod RIP1,input
R15821 T23792 T23793 amod kinase-dependent,input
R15822 T23793 T23795 nsubjpass input,required
R15823 T23794 T23795 auxpass is,required
R15824 T23795 T23795 ROOT required,required
R15825 T23796 T23795 prep for,required
R15826 T23797 T23798 compound Thr308,phosphorylation
R15827 T23798 T23796 pobj phosphorylation,for
R15828 T23799 T23798 prep of,phosphorylation
R15829 T23800 T23799 pobj Akt,of
R15830 T23801 T23800 punct ",",Akt
R15831 T23802 T23806 nsubjpass which,required
R15832 T23803 T23806 prep in,required
R15833 T23804 T23803 pobj turn,in
R15834 T23805 T23806 auxpass is,required
R15835 T23806 T23795 advcl required,required
R15836 T23807 T23806 prep for,required
R15837 T23808 T23809 amod necroptotic,signaling
R15838 T23809 T23807 pobj signaling,for
R15839 T23810 T23795 punct .,required
R15840 T23811 T23812 amod Necroptotic,phosphorylation
R15841 T23812 T23817 nsubj phosphorylation,is
R15842 T23813 T23812 prep of,phosphorylation
R15843 T23814 T23813 pobj Thr308,of
R15844 T23815 T23814 prep of,Thr308
R15845 T23816 T23815 pobj Akt,of
R15846 T23817 T23817 ROOT is,is
R15847 T23818 T23817 acomp sufficient,is
R15848 T23819 T23820 aux to,increase
R15849 T23820 T23818 xcomp increase,sufficient
R15850 T23821 T23822 poss its,activity
R15851 T23822 T23820 dobj activity,increase
R15852 T23823 T23820 prep towards,increase
R15853 T23824 T23825 det a,number
R15854 T23825 T23823 pobj number,towards
R15855 T23826 T23825 prep of,number
R15856 T23827 T23828 amod known,substrates
R15857 T23828 T23826 pobj substrates,of
R15858 T23829 T23828 prep in,substrates
R15859 T23830 T23831 compound L929,cells
R15860 T23831 T23829 pobj cells,in
R15861 T23832 T23831 cc and,cells
R15862 T23833 T23834 poss our,data
R15863 T23834 T23831 conj data,cells
R15864 T23835 T23820 dep reveal,increase
R15865 T23836 T23844 mark that,contributes
R15866 T23837 T23840 det the,pathway
R15867 T23838 T23840 nmod Akt,pathway
R15868 T23839 T23840 compound effector,pathway
R15869 T23840 T23844 nsubj pathway,contributes
R15870 T23841 T23844 nsubj downstream,contributes
R15871 T23842 T23841 prep of,downstream
R15872 T23843 T23842 pobj mTORC1,of
R15873 T23844 T23835 ccomp contributes,reveal
R15874 T23845 T23844 prep to,contributes
R15875 T23846 T23845 pobj necroptosis,to
R15876 T23847 T23835 punct ",",reveal
R15877 T23848 T23849 advmod thereby,identifying
R15878 T23849 T23820 advcl identifying,increase
R15879 T23850 T23852 det a,mediator
R15880 T23851 T23852 amod new,mediator
R15881 T23852 T23849 dobj mediator,identifying
R15882 T23853 T23852 prep of,mediator
R15883 T23854 T23855 det this,form
R15884 T23855 T23853 pobj form,of
R15885 T23856 T23855 prep of,form
R15886 T23857 T23858 compound cell,death
R15887 T23858 T23856 pobj death,of
R15888 T23859 T23817 punct .,is

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T23185 883-889 Protein denotes Thr308
T23184 839-850 Protein denotes RIP1 kinase
T23183 791-801 Positive_regulation denotes activation
T23182 791-801 Positive_regulation denotes activation
T23181 734-744 Positive_regulation denotes sufficient
T23180 818-827 Gene_expression denotes synthesis
T23179 818-827 Gene_expression denotes synthesis
T23178 791-801 Positive_regulation denotes activation
T23177 705-715 Gene_expression denotes expression
T23176 705-715 Gene_expression denotes expression
T23175 813-817 Protein denotes TNFα
T23174 805-808 Protein denotes JNK
T23173 723-726 Protein denotes Akt
T23172 719-722 Protein denotes Myr
T23171 597-607 Gene_expression denotes Expression
T23170 597-607 Gene_expression denotes Expression
T23169 655-658 Protein denotes Akt
T23168 651-654 Protein denotes Myr
T23167 576-588 Localization denotes localization
T23166 592-595 Protein denotes Akt
T23165 463-471 Positive_regulation denotes requires
T23164 440-455 Phosphorylation denotes phosphorylation
T23163 459-462 Protein denotes Akt
T23162 354-364 Positive_regulation denotes activation
T23161 381-390 Gene_expression denotes synthesis
T23160 354-364 Positive_regulation denotes activation
T23159 238-248 Positive_regulation denotes connecting
T23158 366-380 Protein denotes autocrine TNFα
T23157 350-353 Protein denotes JNK
T23156 249-260 Protein denotes RIP1 kinase
T23155 174-182 Positive_regulation denotes increase
T23154 174-182 Positive_regulation denotes increase
T23153 190-205 Phosphorylation denotes phosphorylation
T23152 190-205 Phosphorylation denotes phosphorylation
T23151 64-71 Binding denotes engaged
T23150 209-215 Protein denotes Thr308
T23149 186-189 Protein denotes Akt
T23148 105-116 Protein denotes RIP1 kinase
T23147 37-47 Protein denotes Akt kinase
T23195 979-994 Phosphorylation denotes phosphorylation
T23194 979-994 Phosphorylation denotes phosphorylation
T23193 1166-1172 Protein denotes mTORC1
T23192 1008-1011 Protein denotes Akt
T23191 998-1004 Protein denotes Thr308
T23190 870-878 Positive_regulation denotes required
T23189 870-878 Positive_regulation denotes required
T23188 890-905 Phosphorylation denotes phosphorylation
T23187 890-905 Phosphorylation denotes phosphorylation
T23186 909-912 Protein denotes Akt
R15481 T23147 T23151 themeOf Akt kinase,engaged
R15482 T23149 T23152 themeOf Akt,phosphorylation
R15483 T23150 T23153 themeOf Thr308,phosphorylation
R15484 T23152 T23154 themeOf phosphorylation,increase
R15485 T23153 T23155 themeOf phosphorylation,increase
R15486 T23156 T23159 themeOf RIP1 kinase,connecting
R15487 T23157 T23160 themeOf JNK,activation
R15488 T23158 T23161 themeOf autocrine TNFα,synthesis
R15489 T23161 T23162 themeOf synthesis,activation
R15490 T23163 T23164 themeOf Akt,phosphorylation
R15491 T23164 T23165 themeOf phosphorylation,requires
R15492 T23166 T23167 themeOf Akt,localization
R15493 T23168 T23170 themeOf Myr,Expression
R15494 T23169 T23171 themeOf Akt,Expression
R15495 T23172 T23176 themeOf Myr,expression
R15496 T23173 T23177 themeOf Akt,expression
R15497 T23174 T23178 themeOf JNK,activation
R15498 T23174 T23179 themeOf JNK,synthesis
R15499 T23175 T23180 themeOf TNFα,synthesis
R15500 T23178 T23181 themeOf activation,sufficient
R15501 T23179 T23182 themeOf synthesis,activation
R15502 T23180 T23183 themeOf synthesis,activation
R15503 T23185 T23187 themeOf Thr308,phosphorylation
R15504 T23186 T23188 themeOf Akt,phosphorylation
R15505 T23187 T23189 themeOf phosphorylation,required
R15506 T23188 T23190 themeOf phosphorylation,required
R15507 T23191 T23194 themeOf Thr308,phosphorylation
R15508 T23192 T23195 themeOf Akt,phosphorylation

test3

Id Subject Object Predicate Lexical cue
T20865 979-994 Phosphorylation denotes phosphorylation
T20864 890-905 Phosphorylation denotes phosphorylation
T20863 870-878 Positive_regulation denotes required
T20862 839-843 Protein denotes RIP1
T20861 818-827 Gene_expression denotes synthesis
T20860 813-817 Protein denotes TNFα
T20859 719-726 Protein denotes Myr-Akt
T20858 705-715 Gene_expression denotes expression
T20857 651-658 Protein denotes Myr-Akt
T20856 576-588 Localization denotes localization
T20855 440-455 Phosphorylation denotes phosphorylation
T20854 381-390 Gene_expression denotes synthesis
T20853 376-380 Protein denotes TNFα
T20852 249-253 Protein denotes RIP1
T20851 190-205 Phosphorylation denotes phosphorylation
T20850 174-182 Positive_regulation denotes increase
T20849 152-161 Positive_regulation denotes promoting
T20848 105-109 Protein denotes RIP1
T20810 651-658 Protein denotes Myr-Akt
T20809 376-380 Protein denotes TNFα
T20808 249-253 Protein denotes RIP1
T20807 105-109 Protein denotes RIP1
T20813 839-843 Protein denotes RIP1
T20812 813-817 Protein denotes TNFα
T20811 719-726 Protein denotes Myr-Akt
R13935 T20850 T20849 themeOf increase,promoting
R13936 T20851 T20850 themeOf phosphorylation,increase
R13937 T20853 T20854 themeOf TNFα,synthesis
R13938 T20859 T20858 themeOf Myr-Akt,expression
R13939 T20860 T20861 themeOf TNFα,synthesis
R13940 T20864 T20863 themeOf phosphorylation,required