PMC:3585731 / 39862-39989 JSON TXT

Annnotations TAB JSON ListView MergeView

Id	Subject	Object	Predicate	Lexical cue
T18205	57-72	Phosphorylation	denotes	phosphorylation
T18204	39-46	Negative_regulation	denotes	inhibit
R12102	T18205	T18204	themeOf	phosphorylation,inhibit

Id	Subject	Object	Predicate	Lexical cue
T18932	120-126	NN	denotes	system
T18931	115-119	DT	denotes	this
T18930	112-114	IN	denotes	in
T18929	103-111	NN	denotes	SP600125
T18928	100-102	IN	denotes	of
T18927	96-99	NN	denotes	use
T18926	92-95	DT	denotes	the
T18925	81-91	VB	denotes	precluding
T18924	79-80	-COMMA-	denotes	,
T18923	73-79	NN	denotes	levels
T18922	57-72	NN	denotes	phosphorylation
T18921	53-56	NN	denotes	Akt
T18920	47-52	JJ	denotes	basal
T18919	39-46	VB	denotes	inhibit
T18918	33-38	MD	denotes	could
T18917	25-32	NN	denotes	effects
T18916	14-24	JJ	denotes	off-target
T18915	8-13	DT	denotes	these
T18914	5-7	IN	denotes	of
T18913	0-4	DT	denotes	Both
R12565	T18913	T18914	arg1Of	Both,of
R12566	T18913	T18918	arg1Of	Both,could
R12567	T18913	T18919	arg1Of	Both,inhibit
R12568	T18917	T18914	arg2Of	effects,of
R12569	T18917	T18915	arg1Of	effects,these
R12570	T18917	T18916	arg1Of	effects,off-target
R12571	T18919	T18918	arg2Of	inhibit,could
R12572	T18919	T18924	arg1Of	inhibit,","
R12573	T18919	T18925	modOf	inhibit,precluding
R12574	T18923	T18919	arg2Of	levels,inhibit
R12575	T18923	T18920	arg1Of	levels,basal
R12576	T18923	T18921	arg1Of	levels,Akt
R12577	T18923	T18922	arg1Of	levels,phosphorylation
R12578	T18927	T18925	arg2Of	use,precluding
R12579	T18927	T18926	arg1Of	use,the
R12580	T18927	T18928	arg1Of	use,of
R12581	T18927	T18930	arg1Of	use,in
R12582	T18929	T18928	arg2Of	SP600125,of
R12583	T18932	T18930	arg2Of	system,in
R12584	T18932	T18931	arg1Of	system,this

Id	Subject	Object	Predicate	Lexical cue
T19381	53-56	http://www.uniprot.org/uniprot/Q9Y243	denotes	Akt
T19337	53-56	http://www.uniprot.org/uniprot/P31749	denotes	Akt
T19359	53-56	http://www.uniprot.org/uniprot/P31751	denotes	Akt

Id	Subject	Object	Predicate	Lexical cue
T18449	57-72	http://purl.obolibrary.org/obo/GO_0016310	denotes	phosphorylation

Id	Subject	Object	Predicate	Lexical cue
T18326	0-127	Sentence	denotes	Both of these off-target effects could inhibit basal Akt phosphorylation levels, precluding the use of SP600125 in this system.
T247	0-127	Sentence	denotes	Both of these off-target effects could inhibit basal Akt phosphorylation levels, precluding the use of SP600125 in this system.

Id	Subject	Object	Predicate	Lexical cue
T19883	47-80	Phosphorylation	denotes	basal Akt phosphorylation levels,
T19856	100-111	Entity	denotes	of SP600125
T19844	53-56	Protein	denotes	Akt
R13139	T19844	T19883	themeOf	Akt,"basal Akt phosphorylation levels,"

Id	Subject	Object	Predicate	Lexical cue
T20320	47-52	JJ	denotes	basal
T20319	39-46	VB	denotes	inhibit
T20318	33-38	MD	denotes	could
T20317	25-32	NNS	denotes	effects
T20316	14-24	JJ	denotes	off-target
T20315	8-13	DT	denotes	these
T20314	5-7	IN	denotes	of
T20313	0-4	DT	denotes	Both
T20333	126-127	.	denotes	.
T20332	120-126	NN	denotes	system
T20331	115-119	DT	denotes	this
T20330	112-114	IN	denotes	in
T20329	103-111	CD	denotes	SP600125
T20328	100-102	IN	denotes	of
T20327	96-99	NN	denotes	use
T20326	92-95	DT	denotes	the
T20325	81-91	VBG	denotes	precluding
T20324	79-80	,	denotes	,
T20323	73-79	NNS	denotes	levels
T20322	57-72	NN	denotes	phosphorylation
T20321	53-56	NNP	denotes	Akt
R13564	T20313	T20319	nsubj	Both,inhibit
R13565	T20314	T20313	prep	of,Both
R13566	T20315	T20317	det	these,effects
R13567	T20316	T20317	amod	off-target,effects
R13568	T20317	T20314	pobj	effects,of
R13569	T20318	T20319	aux	could,inhibit
R13570	T20319	T20319	ROOT	inhibit,inhibit
R13571	T20320	T20323	amod	basal,levels
R13572	T20321	T20323	compound	Akt,levels
R13573	T20322	T20323	compound	phosphorylation,levels
R13574	T20323	T20319	dobj	levels,inhibit
R13575	T20324	T20319	punct	",",inhibit
R13576	T20325	T20319	advcl	precluding,inhibit
R13577	T20326	T20327	det	the,use
R13578	T20327	T20325	dobj	use,precluding
R13579	T20328	T20327	prep	of,use
R13580	T20329	T20328	pobj	SP600125,of
R13581	T20330	T20327	prep	in,use
R13582	T20331	T20332	det	this,system
R13583	T20332	T20330	pobj	system,in
R13584	T20333	T20319	punct	.,inhibit

Id	Subject	Object	Predicate	Lexical cue
T19612	57-72	Phosphorylation	denotes	phosphorylation
T19611	39-46	Negative_regulation	denotes	inhibit
T19610	53-56	Protein	denotes	Akt
T19613	39-46	Negative_regulation	denotes	inhibit
R13039	T19610	T19611	themeOf	Akt,inhibit
R13040	T19610	T19612	themeOf	Akt,phosphorylation
R13041	T19612	T19613	themeOf	phosphorylation,inhibit

Id	Subject	Object	Predicate	Lexical cue
T18278	57-72	Phosphorylation	denotes	phosphorylation
T18277	39-46	Negative_regulation	denotes	inhibit
R12115	T18278	T18277	themeOf	phosphorylation,inhibit