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PMC:3585731 / 37088-38084 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T18159 825-829 Protein denotes RIP1
T18158 749-756 Protein denotes Myr-Akt
T18157 662-669 Protein denotes Myr-Akt
T18156 286-290 Protein denotes RIP1
T18155 30-34 Protein denotes RIP1
T18191 899-913 Positive_regulation denotes in response to
T18190 876-891 Phosphorylation denotes phosphorylation
T18189 856-864 Positive_regulation denotes required
T18188 735-745 Gene_expression denotes expression
T18187 598-608 Gene_expression denotes Expression
T18186 577-589 Localization denotes localization
T18185 548-553 Positive_regulation denotes leads
T18184 521-528 Positive_regulation denotes induced
T18183 441-456 Phosphorylation denotes phosphorylation
T18182 342-357 Phosphorylation denotes phosphorylation
T18181 326-334 Positive_regulation denotes increase
T18180 305-310 Positive_regulation denotes leads
R12082 T18157 T18187 themeOf Myr-Akt,Expression
R12083 T18158 T18188 themeOf Myr-Akt,expression
R12095 T18181 T18180 themeOf increase,leads
R12096 T18182 T18181 themeOf phosphorylation,increase
R12097 T18186 T18185 themeOf localization,leads
R12098 T18190 T18191 themeOf phosphorylation,in response to
R12099 T18190 T18189 themeOf phosphorylation,required

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T18684 989-995 NN denotes signal
T18683 977-988 JJ denotes necroptotic
T18682 973-976 DT denotes the
T18681 970-972 IN denotes of
T18680 958-969 NN denotes propagation
T18679 954-957 DT denotes the
T18678 950-953 IN denotes for
T18677 940-949 JJ denotes essential
T18676 937-939 VB denotes is
T18675 933-936 CC denotes and
T18674 922-932 NN denotes inhibition
T18673 914-921 NN denotes caspase
T18672 911-913 TO denotes to
T18671 902-910 NN denotes response
T18670 899-901 IN denotes in
T18669 895-898 NN denotes Akt
T18668 892-894 IN denotes of
T18667 876-891 NN denotes phosphorylation
T18666 869-875 NN denotes Thr308
T18665 865-868 IN denotes for
T18664 856-864 VB denotes required
T18663 853-855 VB denotes is
T18662 847-852 NN denotes input
T18661 830-846 JJ denotes kinase-dependent
T18660 825-829 NN denotes RIP1
T18659 823-824 -COMMA- denotes ,
T18658 817-823 JJ denotes second
T18657 815-816 DT denotes A
T18656 802-813 NN denotes necroptosis
T18655 799-801 IN denotes of
T18654 789-798 NN denotes induction
T18653 785-788 DT denotes the
T18652 781-784 IN denotes for
T18651 770-780 JJ denotes sufficient
T18650 766-769 RB denotes not
T18649 763-765 VB denotes is
T18648 757-762 RB denotes alone
T18647 749-756 NN denotes Myr-Akt
T18646 746-748 IN denotes of
T18645 735-745 NN denotes expression
T18644 733-734 -COMMA- denotes ,
T18643 729-733 NN denotes time
T18642 724-728 JJ denotes same
T18641 720-723 DT denotes the
T18640 717-719 IN denotes At
T18639 708-715 NN denotes factors
T18638 701-707 NN denotes growth
T18637 697-700 IN denotes for
T18636 685-696 NN denotes requirement
T18635 681-684 DT denotes the
T18634 671-680 VB denotes overcomes
T18633 669-670 -COMMA- denotes ,
T18632 662-669 NN denotes Myr-Akt
T18631 660-661 -COMMA- denotes ,
T18630 651-660 NN denotes construct
T18629 647-650 NN denotes Akt
T18628 629-646 JJ denotes membrane-targeted
T18627 614-628 RB denotes constitutively
T18626 612-613 DT denotes a
T18625 609-611 IN denotes of
T18624 598-608 NNP denotes Expression
T18623 593-597 NNP denotes Akt.
T18622 590-592 IN denotes of
T18621 577-589 NN denotes localization
T18620 568-576 NN denotes membrane
T18619 561-567 NN denotes plasma
T18618 557-560 DT denotes the
T18617 554-556 TO denotes to
T18616 548-553 VB denotes leads
T18615 546-547 -COMMA- denotes ,
T18614 539-546 NN denotes factors
T18613 532-538 NN denotes growth
T18612 529-531 IN denotes by
T18611 521-528 VB denotes induced
T18610 518-520 VB denotes is
T18609 512-517 WDT denotes which
T18608 510-511 -COMMA- denotes ,
T18607 505-510 NN denotes input
T18606 499-504 JJ denotes first
T18605 495-498 DT denotes The
T18604 486-493 NN denotes signals
T18603 477-485 JJ denotes distinct
T18602 473-476 CD denotes two
T18601 464-472 VB denotes requires
T18600 460-463 NN denotes Akt
T18599 457-459 IN denotes of
T18598 441-456 NN denotes phosphorylation
T18597 418-440 JJ denotes necroptosis-associated
T18596 416-417 -COMMA- denotes ,
T18595 415-416 -RRB- denotes )
T18594 414-415 CD denotes 9
T18593 409-413 NN denotes Fig.
T18592 408-409 -LRB- denotes (
T18591 402-407 NN denotes model
T18590 398-401 PRP-DOLLAR- denotes our
T18589 395-397 TO denotes to
T18588 385-394 VB denotes According
T18587 377-383 NN denotes Ser473
T18586 373-376 RB denotes not
T18585 369-372 CC denotes but
T18584 367-368 -COMMA- denotes ,
T18583 361-367 NN denotes Thr308
T18582 358-360 IN denotes on
T18581 342-357 NN denotes phosphorylation
T18580 338-341 PRP-DOLLAR- denotes its
T18579 335-337 IN denotes in
T18578 326-334 NN denotes increase
T18577 316-325 JJ denotes selective
T18576 314-315 DT denotes a
T18575 311-313 TO denotes to
T18574 305-310 VB denotes leads
T18573 299-304 WDT denotes which
T18572 297-298 -COMMA- denotes ,
T18571 291-297 NN denotes kinase
T18570 286-290 NN denotes RIP1
T18569 281-285 IN denotes from
T18568 270-280 RB denotes downstream
T18567 260-269 VB denotes signaling
T18566 257-259 IN denotes in
T18565 249-256 VB denotes engaged
T18564 236-248 RB denotes specifically
T18563 233-235 VB denotes is
T18562 226-232 NN denotes kinase
T18561 222-225 NN denotes Akt
T18560 217-221 IN denotes that
T18559 209-216 VB denotes suggest
T18558 201-208 NN denotes results
T18557 197-200 PRP-DOLLAR- denotes our
T18556 195-196 -COMMA- denotes ,
T18555 185-195 RB denotes Altogether
T18554 175-183 NN denotes zVAD.fmk
T18553 165-174 NN denotes inhibitor
T18552 153-164 NN denotes pan-caspase
T18551 149-152 DT denotes the
T18550 144-148 IN denotes with
T18549 136-143 VB denotes treated
T18548 131-135 WRB denotes when
T18547 119-130 NN denotes necroptosis
T18546 116-118 IN denotes by
T18545 112-115 VB denotes die
T18544 107-111 WDT denotes that
T18543 101-106 NN denotes cells
T18542 96-100 NN denotes L929
T18541 83-95 NN denotes fibrosarcoma
T18540 77-82 NN denotes mouse
T18539 71-76 VB denotes using
T18538 62-70 NN denotes pathways
T18537 52-61 NN denotes signaling
T18536 35-51 JJ denotes kinase-dependent
T18535 30-34 NN denotes RIP1
T18534 17-29 VB denotes investigated
T18533 14-16 PRP denotes we
T18532 8-13 NN denotes study
T18531 3-7 DT denotes this
T18530 0-2 IN denotes In
R12176 T18532 T18530 arg2Of study,In
R12177 T18532 T18531 arg1Of study,this
R12178 T18533 T18534 arg1Of we,investigated
R12179 T18534 T18530 arg1Of investigated,In
R12180 T18538 T18534 arg2Of pathways,investigated
R12181 T18538 T18535 arg1Of pathways,RIP1
R12182 T18538 T18536 arg1Of pathways,kinase-dependent
R12183 T18538 T18537 arg1Of pathways,signaling
R12184 T18538 T18539 arg1Of pathways,using
R12185 T18543 T18539 arg2Of cells,using
R12186 T18543 T18540 arg1Of cells,mouse
R12187 T18543 T18541 arg1Of cells,fibrosarcoma
R12188 T18543 T18542 arg1Of cells,L929
R12189 T18543 T18544 arg1Of cells,that
R12190 T18543 T18545 arg1Of cells,die
R12191 T18545 T18546 arg1Of die,by
R12192 T18545 T18548 arg1Of die,when
R12193 T18547 T18546 arg2Of necroptosis,by
R12194 T18549 T18548 arg2Of treated,when
R12195 T18549 T18550 arg1Of treated,with
R12196 T18554 T18550 arg2Of zVAD.fmk,with
R12197 T18554 T18551 arg1Of zVAD.fmk,the
R12198 T18554 T18552 arg1Of zVAD.fmk,pan-caspase
R12199 T18554 T18553 arg1Of zVAD.fmk,inhibitor
R12200 T18558 T18557 arg1Of results,our
R12201 T18558 T18559 arg1Of results,suggest
R12202 T18559 T18555 arg1Of suggest,Altogether
R12203 T18559 T18556 arg1Of suggest,","
R12204 T18562 T18561 arg1Of kinase,Akt
R12205 T18562 T18563 arg1Of kinase,is
R12206 T18562 T18565 arg2Of kinase,engaged
R12207 T18565 T18559 arg2Of engaged,suggest
R12208 T18565 T18560 arg1Of engaged,that
R12209 T18565 T18563 arg2Of engaged,is
R12210 T18565 T18564 arg1Of engaged,specifically
R12211 T18565 T18566 arg1Of engaged,in
R12212 T18567 T18566 arg2Of signaling,in
R12213 T18567 T18568 arg1Of signaling,downstream
R12214 T18567 T18569 arg1Of signaling,from
R12215 T18571 T18569 arg2Of kinase,from
R12216 T18571 T18570 arg1Of kinase,RIP1
R12217 T18571 T18572 arg1Of kinase,","
R12218 T18571 T18573 arg1Of kinase,which
R12219 T18571 T18574 arg1Of kinase,leads
R12220 T18574 T18575 arg1Of leads,to
R12221 T18578 T18575 arg2Of increase,to
R12222 T18578 T18576 arg1Of increase,a
R12223 T18578 T18577 arg1Of increase,selective
R12224 T18578 T18579 arg1Of increase,in
R12225 T18581 T18582 arg1Of phosphorylation,on
R12226 T18581 T18585 arg1Of phosphorylation,but
R12227 T18583 T18582 arg2Of Thr308,on
R12228 T18585 T18579 arg2Of but,in
R12229 T18585 T18580 arg1Of but,its
R12230 T18585 T18584 arg1Of but,","
R12231 T18585 T18586 arg1Of but,not
R12232 T18587 T18585 arg2Of Ser473,but
R12233 T18589 T18588 arg2Of to,According
R12234 T18591 T18589 arg2Of model,to
R12235 T18591 T18590 arg1Of model,our
R12236 T18591 T18592 arg1Of model,(
R12237 T18593 T18592 arg2Of Fig.,(
R12238 T18593 T18594 arg1Of Fig.,9
R12239 T18595 T18592 arg3Of ),(
R12240 T18598 T18597 arg1Of phosphorylation,necroptosis-associated
R12241 T18598 T18599 arg1Of phosphorylation,of
R12242 T18598 T18601 arg1Of phosphorylation,requires
R12243 T18600 T18599 arg2Of Akt,of
R12244 T18601 T18588 arg1Of requires,According
R12245 T18601 T18596 arg1Of requires,","
R12246 T18604 T18601 arg2Of signals,requires
R12247 T18604 T18602 arg1Of signals,two
R12248 T18604 T18603 arg1Of signals,distinct
R12249 T18607 T18605 arg1Of input,The
R12250 T18607 T18606 arg1Of input,first
R12251 T18607 T18608 arg1Of input,","
R12252 T18607 T18609 arg1Of input,which
R12253 T18607 T18610 arg1Of input,is
R12254 T18607 T18611 arg2Of input,induced
R12255 T18607 T18616 arg1Of input,leads
R12256 T18607 T18631 arg1Of input,","
R12257 T18607 T18634 arg1Of input,overcomes
R12258 T18611 T18610 arg2Of induced,is
R12259 T18611 T18615 arg1Of induced,","
R12260 T18614 T18611 arg1Of factors,induced
R12261 T18614 T18612 arg2Of factors,by
R12262 T18614 T18613 arg1Of factors,growth
R12263 T18616 T18615 arg2Of leads,","
R12264 T18616 T18617 arg1Of leads,to
R12265 T18621 T18617 arg2Of localization,to
R12266 T18621 T18618 arg1Of localization,the
R12267 T18621 T18619 arg1Of localization,plasma
R12268 T18621 T18620 arg1Of localization,membrane
R12269 T18621 T18622 arg1Of localization,of
R12270 T18624 T18622 arg2Of Expression,of
R12271 T18624 T18623 arg1Of Expression,Akt.
R12272 T18624 T18625 arg1Of Expression,of
R12273 T18628 T18627 arg1Of membrane-targeted,constitutively
R12274 T18630 T18625 arg2Of construct,of
R12275 T18630 T18626 arg1Of construct,a
R12276 T18630 T18628 arg1Of construct,membrane-targeted
R12277 T18630 T18629 arg1Of construct,Akt
R12278 T18632 T18631 arg2Of Myr-Akt,","
R12279 T18634 T18633 arg1Of overcomes,","
R12280 T18636 T18634 arg2Of requirement,overcomes
R12281 T18636 T18635 arg1Of requirement,the
R12282 T18636 T18637 arg1Of requirement,for
R12283 T18639 T18637 arg2Of factors,for
R12284 T18639 T18638 arg1Of factors,growth
R12285 T18643 T18640 arg2Of time,At
R12286 T18643 T18641 arg1Of time,the
R12287 T18643 T18642 arg1Of time,same
R12288 T18645 T18646 arg1Of expression,of
R12289 T18645 T18649 arg1Of expression,is
R12290 T18645 T18651 arg1Of expression,sufficient
R12291 T18647 T18646 arg2Of Myr-Akt,of
R12292 T18647 T18648 arg1Of Myr-Akt,alone
R12293 T18649 T18640 arg1Of is,At
R12294 T18649 T18644 arg1Of is,","
R12295 T18649 T18650 arg1Of is,not
R12296 T18651 T18649 arg2Of sufficient,is
R12297 T18651 T18652 arg1Of sufficient,for
R12298 T18654 T18652 arg2Of induction,for
R12299 T18654 T18653 arg1Of induction,the
R12300 T18654 T18655 arg1Of induction,of
R12301 T18656 T18655 arg2Of necroptosis,of
R12302 T18658 T18659 arg1Of second,","
R12303 T18661 T18659 arg2Of kinase-dependent,","
R12304 T18661 T18660 arg1Of kinase-dependent,RIP1
R12305 T18662 T18657 arg1Of input,A
R12306 T18662 T18658 arg1Of input,second
R12307 T18662 T18661 arg1Of input,kinase-dependent
R12308 T18662 T18663 arg1Of input,is
R12309 T18662 T18664 arg2Of input,required
R12310 T18662 T18676 arg1Of input,is
R12311 T18662 T18677 arg1Of input,essential
R12312 T18664 T18663 arg2Of required,is
R12313 T18664 T18665 arg1Of required,for
R12314 T18664 T18670 arg1Of required,in
R12315 T18664 T18675 arg1Of required,and
R12316 T18667 T18665 arg2Of phosphorylation,for
R12317 T18667 T18666 arg1Of phosphorylation,Thr308
R12318 T18667 T18668 arg1Of phosphorylation,of
R12319 T18669 T18668 arg2Of Akt,of
R12320 T18670 T18672 arg1Of in,to
R12321 T18671 T18670 arg2Of response,in
R12322 T18674 T18670 arg3Of inhibition,in
R12323 T18674 T18673 arg1Of inhibition,caspase
R12324 T18676 T18675 arg2Of is,and
R12325 T18677 T18676 arg2Of essential,is
R12326 T18677 T18678 arg1Of essential,for
R12327 T18680 T18678 arg2Of propagation,for
R12328 T18680 T18679 arg1Of propagation,the
R12329 T18680 T18681 arg1Of propagation,of
R12330 T18684 T18681 arg2Of signal,of
R12331 T18684 T18682 arg1Of signal,the
R12332 T18684 T18683 arg1Of signal,necroptotic

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T18393 825-829 Protein denotes RIP1
T18392 749-756 Protein denotes Myr-Akt
T18391 662-669 Protein denotes Myr-Akt
T18390 286-290 Protein denotes RIP1
T18389 30-34 Protein denotes RIP1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T19370 895-898 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19369 753-756 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19368 666-669 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19367 647-650 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19366 593-596 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19365 460-463 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19364 222-225 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T19348 895-898 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19347 753-756 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19346 666-669 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19345 647-650 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19344 593-596 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19343 460-463 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19342 222-225 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19326 895-898 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19325 753-756 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19324 666-669 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19323 647-650 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19322 593-596 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19321 460-463 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19320 222-225 http://www.uniprot.org/uniprot/P31749 denotes Akt
T19317 825-829 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T19316 286-290 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T19315 30-34 http://www.uniprot.org/uniprot/Q13546 denotes RIP1

GO-BP

Id Subject Object Predicate Lexical cue
T18459 577-589 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T18458 568-589 http://purl.obolibrary.org/obo/GO_0051668 denotes membrane localization
T18457 561-589 http://purl.obolibrary.org/obo/GO_0072659 denotes plasma membrane localization
T18456 561-589 http://purl.obolibrary.org/obo/GO_0044856 denotes plasma membrane localization
T18455 701-707 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T18454 532-538 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T18445 876-891 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18444 441-456 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18443 342-357 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18437 802-813 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T18436 418-429 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T18435 119-130 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T18433 789-813 http://purl.obolibrary.org/obo/GO_0070266 denotes induction of necroptosis
T18428 802-813 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T18427 418-429 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T18426 119-130 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T18425 52-70 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T18423 260-269 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T18422 52-61 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling

GO-CC

Id Subject Object Predicate Lexical cue
T18489 629-637 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T18488 568-576 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T18487 561-576 http://purl.obolibrary.org/obo/GO_0005886 denotes plasma membrane
T18481 101-106 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T18318 815-996 Sentence denotes A second, RIP1 kinase-dependent input is required for Thr308 phosphorylation of Akt in response to caspase inhibition and is essential for the propagation of the necroptotic signal.
T18317 717-814 Sentence denotes At the same time, expression of Myr-Akt alone is not sufficient for the induction of necroptosis.
T18316 495-716 Sentence denotes The first input, which is induced by growth factors, leads to the plasma membrane localization of Akt. Expression of a constitutively membrane-targeted Akt construct, Myr-Akt, overcomes the requirement for growth factors.
T18315 385-494 Sentence denotes According to our model (Fig. 9), necroptosis-associated phosphorylation of Akt requires two distinct signals.
T18314 185-384 Sentence denotes Altogether, our results suggest that Akt kinase is specifically engaged in signaling downstream from RIP1 kinase, which leads to a selective increase in its phosphorylation on Thr308, but not Ser473.
T18313 0-184 Sentence denotes In this study we investigated RIP1 kinase-dependent signaling pathways using mouse fibrosarcoma L929 cells that die by necroptosis when treated with the pan-caspase inhibitor zVAD.fmk.
T229 0-184 Sentence denotes In this study we investigated RIP1 kinase-dependent signaling pathways using mouse fibrosarcoma L929 cells that die by necroptosis when treated with the pan-caspase inhibitor zVAD.fmk.
T230 185-384 Sentence denotes Altogether, our results suggest that Akt kinase is specifically engaged in signaling downstream from RIP1 kinase, which leads to a selective increase in its phosphorylation on Thr308, but not Ser473.
T231 385-494 Sentence denotes According to our model (Fig. 9), necroptosis-associated phosphorylation of Akt requires two distinct signals.
T232 495-597 Sentence denotes The first input, which is induced by growth factors, leads to the plasma membrane localization of Akt.
T233 598-716 Sentence denotes Expression of a constitutively membrane-targeted Akt construct, Myr-Akt, overcomes the requirement for growth factors.
T234 717-814 Sentence denotes At the same time, expression of Myr-Akt alone is not sufficient for the induction of necroptosis.
T235 815-996 Sentence denotes A second, RIP1 kinase-dependent input is required for Thr308 phosphorylation of Akt in response to caspase inhibition and is essential for the propagation of the necroptotic signal.

simple1

Id Subject Object Predicate Lexical cue
T18496 825-829 Protein denotes RIP1
T18495 749-756 Protein denotes Myr-Akt
T18494 662-669 Protein denotes Myr-Akt
T18493 286-290 Protein denotes RIP1
T18492 30-34 Protein denotes RIP1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T19296 735-745 Gene_expression denotes expression
T19295 770-780 Positive_regulation denotes sufficient
T19294 598-608 Gene_expression denotes Expression
T19273 825-829 Protein denotes RIP1
T19272 749-756 Protein denotes Myr-Akt
T19271 662-669 Protein denotes Myr-Akt
T19270 286-290 Protein denotes RIP1
T19269 30-34 Protein denotes RIP1
R12906 T19271 T19294 themeOf Myr-Akt,Expression
R12907 T19272 T19296 themeOf Myr-Akt,expression
R12924 T19296 T19295 themeOf expression,sufficient

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T19496 825-829 Protein denotes RIP1
T19495 749-756 Protein denotes Myr-Akt
T19494 662-669 Protein denotes Myr-Akt
T19493 286-290 Protein denotes RIP1
T19492 30-34 Protein denotes RIP1
T19519 830-846 Regulation denotes kinase-dependent
T19518 735-745 Gene_expression denotes expression
T19517 598-608 Gene_expression denotes Expression
R12974 T19494 T19517 themeOf Myr-Akt,Expression
R12975 T19495 T19518 themeOf Myr-Akt,expression
R12976 T19496 T19519 themeOf RIP1,kinase-dependent

DLUT931

Id Subject Object Predicate Lexical cue
T19429 830-846 Positive_regulation denotes kinase-dependent
T19428 770-780 Positive_regulation denotes sufficient
T19427 735-745 Gene_expression denotes expression
T19426 598-608 Gene_expression denotes Expression
T19425 305-310 Positive_regulation denotes leads
T19404 825-829 Protein denotes RIP1
T19403 749-756 Protein denotes Myr-Akt
T19402 662-669 Protein denotes Myr-Akt
T19401 286-290 Protein denotes RIP1
T19400 30-34 Protein denotes RIP1
R12932 T19401 T19425 themeOf RIP1,leads
R12933 T19402 T19426 themeOf Myr-Akt,Expression
R12934 T19403 T19427 themeOf Myr-Akt,expression
R12935 T19404 T19429 themeOf RIP1,kinase-dependent
R12947 T19427 T19428 themeOf expression,sufficient

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T19897 869-898 Phosphorylation denotes Thr308 phosphorylation of Akt
T19888 418-463 Phosphorylation denotes necroptosis-associated phosphorylation of Akt
T19886 914-932 Negative_regulation denotes caspase inhibition
T19881 735-756 Gene_expression denotes expression of Myr-Akt
T19877 590-596 Protein denotes of Akt
T19868 662-669 Protein denotes Myr-Akt
T19865 222-225 Protein denotes Akt
T19863 165-174 Entity denotes inhibitor
T19861 746-756 Protein denotes of Myr-Akt
T19852 286-290 Protein denotes RIP1
T19841 629-646 Entity denotes membrane-targeted
T19839 647-650 Protein denotes Akt
T19838 222-232 Protein denotes Akt kinase
T19835 869-875 Entity denotes Thr308
T19834 557-576 Entity denotes the plasma membrane
T19830 149-183 Entity denotes the pan-caspase inhibitor zVAD.fmk
T19826 30-34 Protein denotes RIP1
T19823 149-183 Protein denotes the pan-caspase inhibitor zVAD.fmk
T19822 286-298 Protein denotes RIP1 kinase,
T19812 35-51 Protein denotes kinase-dependent
T19804 377-383 Entity denotes Ser473
T19801 825-829 Protein denotes RIP1
T19794 358-367 Entity denotes on Thr308
T19788 77-106 Entity denotes mouse fibrosarcoma L929 cells
T19786 457-463 Protein denotes of Akt
T19785 830-846 Protein denotes kinase-dependent
T19784 892-898 Protein denotes of Akt
T19781 914-921 Protein denotes caspase
T19777 77-106 Entity denotes mouse fibrosarcoma L929 cells
R13124 T19781 T19886 themeOf caspase,caspase inhibition
R13125 T19784 T19897 themeOf of Akt,Thr308 phosphorylation of Akt
R13126 T19786 T19888 themeOf of Akt,necroptosis-associated phosphorylation of Akt
R13136 T19835 T19784 partOf Thr308,of Akt
R13137 T19835 T19897 siteOf Thr308,Thr308 phosphorylation of Akt
R13145 T19861 T19881 themeOf of Myr-Akt,expression of Myr-Akt

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T19924 71-76 VBG denotes using
T19923 62-70 NNS denotes pathways
T19922 52-61 VBG denotes signaling
T19921 35-51 JJ denotes kinase-dependent
T19920 30-34 NNP denotes RIP1
T19919 17-29 VBD denotes investigated
T19918 14-16 PRP denotes we
T19917 8-13 NN denotes study
T19916 3-7 DT denotes this
T19915 0-2 IN denotes In
T20076 995-996 . denotes .
T20075 989-995 NN denotes signal
T20074 977-988 JJ denotes necroptotic
T20073 973-976 DT denotes the
T20072 970-972 IN denotes of
T20071 958-969 NN denotes propagation
T20070 954-957 DT denotes the
T20069 950-953 IN denotes for
T20068 940-949 JJ denotes essential
T20067 937-939 VBZ denotes is
T20066 933-936 CC denotes and
T20065 922-932 NN denotes inhibition
T20064 914-921 VB denotes caspase
T20063 911-913 TO denotes to
T20062 902-910 NN denotes response
T20061 899-901 IN denotes in
T20060 895-898 NNP denotes Akt
T20059 892-894 IN denotes of
T20058 876-891 NN denotes phosphorylation
T20057 869-875 NNP denotes Thr308
T20056 865-868 IN denotes for
T20055 856-864 VBN denotes required
T20054 853-855 VBZ denotes is
T20053 847-852 NN denotes input
T20052 830-846 JJ denotes kinase-dependent
T20051 825-829 JJ denotes RIP1
T20050 823-824 , denotes ,
T20049 817-823 JJ denotes second
T20048 815-816 DT denotes A
T20047 813-814 . denotes .
T20046 802-813 NN denotes necroptosis
T20045 799-801 IN denotes of
T20044 789-798 NN denotes induction
T20043 785-788 DT denotes the
T20042 781-784 IN denotes for
T20041 770-780 JJ denotes sufficient
T20040 766-769 RB denotes not
T20039 763-765 VBZ denotes is
T20038 757-762 RB denotes alone
T20037 749-756 NNP denotes Myr-Akt
T20036 746-748 IN denotes of
T20035 735-745 NN denotes expression
T20034 733-734 , denotes ,
T20033 729-733 NN denotes time
T20032 724-728 JJ denotes same
T20031 720-723 DT denotes the
T20030 717-719 IN denotes At
T20029 715-716 . denotes .
T20028 708-715 NNS denotes factors
T20027 701-707 NN denotes growth
T20026 697-700 IN denotes for
T20025 685-696 NN denotes requirement
T20024 681-684 DT denotes the
T20023 671-680 VBZ denotes overcomes
T20022 669-670 , denotes ,
T20021 662-669 NNP denotes Myr-Akt
T20020 660-661 , denotes ,
T20019 651-660 VBP denotes construct
T20018 647-650 NNP denotes Akt
T20017 629-646 JJ denotes membrane-targeted
T20016 614-628 RB denotes constitutively
T20015 612-613 DT denotes a
T20014 609-611 IN denotes of
T20013 598-608 NN denotes Expression
T20012 596-597 . denotes .
T20011 593-596 NNP denotes Akt
T20010 590-592 IN denotes of
T20009 577-589 NN denotes localization
T20008 568-576 NN denotes membrane
T20007 561-567 NN denotes plasma
T20006 557-560 DT denotes the
T20005 554-556 TO denotes to
T20004 548-553 VBZ denotes leads
T20003 546-547 , denotes ,
T20002 539-546 NNS denotes factors
T20001 532-538 NN denotes growth
T20000 529-531 IN denotes by
T19999 521-528 VBN denotes induced
T19998 518-520 VBZ denotes is
T19997 512-517 WDT denotes which
T19996 510-511 , denotes ,
T19995 505-510 NN denotes input
T19994 499-504 JJ denotes first
T19993 495-498 DT denotes The
T19992 493-494 . denotes .
T19991 486-493 NNS denotes signals
T19990 477-485 JJ denotes distinct
T19989 473-476 CD denotes two
T19988 464-472 VBZ denotes requires
T19987 460-463 NNP denotes Akt
T19986 457-459 IN denotes of
T19985 441-456 NN denotes phosphorylation
T19984 418-440 JJ denotes necroptosis-associated
T19983 416-417 , denotes ,
T19982 415-416 -RRB- denotes )
T19981 414-415 CD denotes 9
T19980 409-413 FW denotes Fig.
T19979 408-409 -LRB- denotes (
T19978 402-407 NN denotes model
T19977 398-401 PRP$ denotes our
T19976 395-397 TO denotes to
T19975 385-394 VBG denotes According
T19974 383-384 . denotes .
T19973 377-383 JJ denotes Ser473
T19972 373-376 RB denotes not
T19971 369-372 CC denotes but
T19970 367-368 , denotes ,
T19969 361-367 NNP denotes Thr308
T19968 358-360 IN denotes on
T19967 342-357 NN denotes phosphorylation
T19966 338-341 PRP$ denotes its
T19965 335-337 IN denotes in
T19964 326-334 NN denotes increase
T19963 316-325 JJ denotes selective
T19962 314-315 DT denotes a
T19961 311-313 TO denotes to
T19960 305-310 VBZ denotes leads
T19959 299-304 WDT denotes which
T19958 297-298 , denotes ,
T19957 291-297 NN denotes kinase
T19956 286-290 CD denotes RIP1
T19955 281-285 IN denotes from
T19954 270-280 JJ denotes downstream
T19953 260-269 VBG denotes signaling
T19952 257-259 IN denotes in
T19951 249-256 VBN denotes engaged
T19950 236-248 RB denotes specifically
T19949 233-235 VBZ denotes is
T19948 226-232 NN denotes kinase
T19947 222-225 NNP denotes Akt
T19946 217-221 IN denotes that
T19945 209-216 VBP denotes suggest
T19944 201-208 NNS denotes results
T19943 197-200 PRP$ denotes our
T19942 195-196 , denotes ,
T19941 185-195 RB denotes Altogether
T19940 183-184 . denotes .
T19939 175-183 NNP denotes zVAD.fmk
T19938 165-174 NN denotes inhibitor
T19937 153-164 NN denotes pan-caspase
T19936 149-152 DT denotes the
T19935 144-148 IN denotes with
T19934 136-143 VBN denotes treated
T19933 131-135 WRB denotes when
T19932 119-130 NN denotes necroptosis
T19931 116-118 IN denotes by
T19930 112-115 VBP denotes die
T19929 107-111 WDT denotes that
T19928 101-106 NNS denotes cells
T19927 96-100 NNP denotes L929
T19926 83-95 NN denotes fibrosarcoma
T19925 77-82 NN denotes mouse
R13166 T19915 T19919 prep In,investigated
R13167 T19916 T19917 det this,study
R13168 T19917 T19915 pobj study,In
R13169 T19918 T19919 nsubj we,investigated
R13170 T19919 T19919 ROOT investigated,investigated
R13171 T19920 T19923 nmod RIP1,pathways
R13172 T19921 T19923 amod kinase-dependent,pathways
R13173 T19922 T19923 compound signaling,pathways
R13174 T19923 T19919 dobj pathways,investigated
R13175 T19924 T19919 advcl using,investigated
R13176 T19925 T19928 compound mouse,cells
R13177 T19926 T19927 compound fibrosarcoma,L929
R13178 T19927 T19928 compound L929,cells
R13179 T19928 T19924 dobj cells,using
R13180 T19929 T19930 nsubj that,die
R13181 T19930 T19928 relcl die,cells
R13182 T19931 T19930 prep by,die
R13183 T19932 T19931 pobj necroptosis,by
R13184 T19933 T19934 advmod when,treated
R13185 T19934 T19930 advcl treated,die
R13186 T19935 T19934 prep with,treated
R13187 T19936 T19938 det the,inhibitor
R13188 T19937 T19938 compound pan-caspase,inhibitor
R13189 T19938 T19935 pobj inhibitor,with
R13190 T19939 T19938 appos zVAD.fmk,inhibitor
R13191 T19940 T19919 punct .,investigated
R13192 T19941 T19945 advmod Altogether,suggest
R13193 T19942 T19945 punct ",",suggest
R13194 T19943 T19944 poss our,results
R13195 T19944 T19945 nsubj results,suggest
R13196 T19945 T19945 ROOT suggest,suggest
R13197 T19946 T19951 mark that,engaged
R13198 T19947 T19948 compound Akt,kinase
R13199 T19948 T19951 nsubjpass kinase,engaged
R13200 T19949 T19951 auxpass is,engaged
R13201 T19950 T19951 advmod specifically,engaged
R13202 T19951 T19945 ccomp engaged,suggest
R13203 T19952 T19951 prep in,engaged
R13204 T19953 T19952 pcomp signaling,in
R13205 T19954 T19953 dobj downstream,signaling
R13206 T19955 T19953 prep from,signaling
R13207 T19956 T19957 nummod RIP1,kinase
R13208 T19957 T19955 pobj kinase,from
R13209 T19958 T19957 punct ",",kinase
R13210 T19959 T19960 nsubj which,leads
R13211 T19960 T19957 relcl leads,kinase
R13212 T19961 T19960 prep to,leads
R13213 T19962 T19964 det a,increase
R13214 T19963 T19964 amod selective,increase
R13215 T19964 T19961 pobj increase,to
R13216 T19965 T19964 prep in,increase
R13217 T19966 T19967 poss its,phosphorylation
R13218 T19967 T19965 pobj phosphorylation,in
R13219 T19968 T19967 prep on,phosphorylation
R13220 T19969 T19968 pobj Thr308,on
R13221 T19970 T19964 punct ",",increase
R13222 T19971 T19964 cc but,increase
R13223 T19972 T19973 neg not,Ser473
R13224 T19973 T19964 conj Ser473,increase
R13225 T19974 T19945 punct .,suggest
R13226 T19975 T19988 prep According,requires
R13227 T19976 T19975 prep to,According
R13228 T19977 T19978 poss our,model
R13229 T19978 T19976 pobj model,to
R13230 T19979 T19980 punct (,Fig.
R13231 T19980 T19981 nmod Fig.,9
R13232 T19981 T19978 appos 9,model
R13233 T19982 T19975 punct ),According
R13234 T19983 T19988 punct ",",requires
R13235 T19984 T19985 amod necroptosis-associated,phosphorylation
R13236 T19985 T19988 nsubj phosphorylation,requires
R13237 T19986 T19985 prep of,phosphorylation
R13238 T19987 T19986 pobj Akt,of
R13239 T19988 T19988 ROOT requires,requires
R13240 T19989 T19991 nummod two,signals
R13241 T19990 T19991 amod distinct,signals
R13242 T19991 T19988 dobj signals,requires
R13243 T19992 T19988 punct .,requires
R13244 T19993 T19995 det The,input
R13245 T19994 T19995 amod first,input
R13246 T19995 T20004 nsubj input,leads
R13247 T19996 T19995 punct ",",input
R13248 T19997 T19999 nsubjpass which,induced
R13249 T19998 T19999 auxpass is,induced
R13250 T19999 T19995 relcl induced,input
R13251 T20000 T19999 agent by,induced
R13252 T20001 T20002 compound growth,factors
R13253 T20002 T20000 pobj factors,by
R13254 T20003 T19995 punct ",",input
R13255 T20004 T20004 ROOT leads,leads
R13256 T20005 T20004 prep to,leads
R13257 T20006 T20009 det the,localization
R13258 T20007 T20008 compound plasma,membrane
R13259 T20008 T20009 compound membrane,localization
R13260 T20009 T20005 pobj localization,to
R13261 T20010 T20009 prep of,localization
R13262 T20011 T20010 pobj Akt,of
R13263 T20012 T20004 punct .,leads
R13264 T20013 T20019 nsubj Expression,construct
R13265 T20014 T20013 prep of,Expression
R13266 T20015 T20018 det a,Akt
R13267 T20016 T20017 advmod constitutively,membrane-targeted
R13268 T20017 T20018 amod membrane-targeted,Akt
R13269 T20018 T20014 pobj Akt,of
R13270 T20019 T20023 ccomp construct,overcomes
R13271 T20020 T20019 punct ",",construct
R13272 T20021 T20023 nsubj Myr-Akt,overcomes
R13273 T20022 T20023 punct ",",overcomes
R13274 T20023 T20023 ROOT overcomes,overcomes
R13275 T20024 T20025 det the,requirement
R13276 T20025 T20023 dobj requirement,overcomes
R13277 T20026 T20025 prep for,requirement
R13278 T20027 T20028 compound growth,factors
R13279 T20028 T20026 pobj factors,for
R13280 T20029 T20023 punct .,overcomes
R13281 T20030 T20039 prep At,is
R13282 T20031 T20033 det the,time
R13283 T20032 T20033 amod same,time
R13284 T20033 T20030 pobj time,At
R13285 T20034 T20039 punct ",",is
R13286 T20035 T20039 nsubj expression,is
R13287 T20036 T20035 prep of,expression
R13288 T20037 T20036 pobj Myr-Akt,of
R13289 T20038 T20035 advmod alone,expression
R13290 T20039 T20039 ROOT is,is
R13291 T20040 T20039 neg not,is
R13292 T20041 T20039 acomp sufficient,is
R13293 T20042 T20041 prep for,sufficient
R13294 T20043 T20044 det the,induction
R13295 T20044 T20042 pobj induction,for
R13296 T20045 T20044 prep of,induction
R13297 T20046 T20045 pobj necroptosis,of
R13298 T20047 T20039 punct .,is
R13299 T20048 T20053 det A,input
R13300 T20049 T20053 amod second,input
R13301 T20050 T20053 punct ",",input
R13302 T20051 T20053 amod RIP1,input
R13303 T20052 T20053 amod kinase-dependent,input
R13304 T20053 T20055 nsubjpass input,required
R13305 T20054 T20055 auxpass is,required
R13306 T20055 T20055 ROOT required,required
R13307 T20056 T20055 prep for,required
R13308 T20057 T20058 compound Thr308,phosphorylation
R13309 T20058 T20056 pobj phosphorylation,for
R13310 T20059 T20058 prep of,phosphorylation
R13311 T20060 T20059 pobj Akt,of
R13312 T20061 T20055 prep in,required
R13313 T20062 T20061 pobj response,in
R13314 T20063 T20062 prep to,response
R13315 T20064 T20063 pobj caspase,to
R13316 T20065 T20064 dobj inhibition,caspase
R13317 T20066 T20055 cc and,required
R13318 T20067 T20055 conj is,required
R13319 T20068 T20067 acomp essential,is
R13320 T20069 T20067 prep for,is
R13321 T20070 T20071 det the,propagation
R13322 T20071 T20069 pobj propagation,for
R13323 T20072 T20071 prep of,propagation
R13324 T20073 T20075 det the,signal
R13325 T20074 T20075 amod necroptotic,signal
R13326 T20075 T20072 pobj signal,of
R13327 T20076 T20055 punct .,required

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T19573 856-864 Positive_regulation denotes required
T19572 856-864 Positive_regulation denotes required
T19571 922-932 Negative_regulation denotes inhibition
T19570 876-891 Phosphorylation denotes phosphorylation
T19569 876-891 Phosphorylation denotes phosphorylation
T19568 914-921 Protein denotes caspase
T19567 895-898 Protein denotes Akt
T19566 869-875 Protein denotes Thr308
T19565 825-836 Protein denotes RIP1 kinase
T19564 770-780 Positive_regulation denotes sufficient
T19563 770-780 Positive_regulation denotes sufficient
T19562 735-745 Gene_expression denotes expression
T19561 735-745 Gene_expression denotes expression
T19560 753-756 Protein denotes Akt
T19559 749-752 Protein denotes Myr
T19558 598-608 Gene_expression denotes Expression
T19557 598-608 Gene_expression denotes Expression
T19556 662-669 Protein denotes Myr-Akt
T19555 647-650 Protein denotes Akt
T19554 577-589 Localization denotes localization
T19553 593-596 Protein denotes Akt
T19552 464-472 Positive_regulation denotes requires
T19551 441-456 Phosphorylation denotes phosphorylation
T19550 460-463 Protein denotes Akt
T19549 305-310 Binding denotes leads
T19548 249-256 Binding denotes engaged
T19547 286-297 Protein denotes RIP1 kinase
T19546 222-232 Protein denotes Akt kinase
T19545 157-164 Protein denotes caspase
T19544 30-41 Protein denotes RIP1 kinase
R13003 T19546 T19548 themeOf Akt kinase,engaged
R13004 T19547 T19549 themeOf RIP1 kinase,leads
R13005 T19550 T19551 themeOf Akt,phosphorylation
R13006 T19551 T19552 themeOf phosphorylation,requires
R13007 T19553 T19554 themeOf Akt,localization
R13008 T19555 T19557 themeOf Akt,Expression
R13009 T19556 T19558 themeOf Myr-Akt,Expression
R13010 T19559 T19561 themeOf Myr,expression
R13011 T19560 T19562 themeOf Akt,expression
R13012 T19561 T19563 themeOf expression,sufficient
R13013 T19562 T19564 themeOf expression,sufficient
R13014 T19566 T19569 themeOf Thr308,phosphorylation
R13015 T19567 T19570 themeOf Akt,phosphorylation
R13016 T19568 T19571 themeOf caspase,inhibition
R13017 T19569 T19572 themeOf phosphorylation,required
R13018 T19570 T19573 themeOf phosphorylation,required

test3

Id Subject Object Predicate Lexical cue
T18259 876-891 Phosphorylation denotes phosphorylation
T18258 856-864 Positive_regulation denotes required
T18257 825-829 Protein denotes RIP1
T18256 749-756 Protein denotes Myr-Akt
T18255 735-745 Gene_expression denotes expression
T18254 662-669 Protein denotes Myr-Akt
T18253 598-608 Gene_expression denotes Expression
T18252 577-589 Localization denotes localization
T18251 441-456 Phosphorylation denotes phosphorylation
T18250 342-357 Phosphorylation denotes phosphorylation
T18249 326-334 Positive_regulation denotes increase
T18248 286-290 Protein denotes RIP1
T18247 30-34 Protein denotes RIP1
T18225 825-829 Protein denotes RIP1
T18224 749-756 Protein denotes Myr-Akt
T18223 662-669 Protein denotes Myr-Akt
T18222 286-290 Protein denotes RIP1
T18221 30-34 Protein denotes RIP1
R12106 T18250 T18249 themeOf phosphorylation,increase
R12107 T18254 T18253 themeOf Myr-Akt,Expression
R12108 T18256 T18255 themeOf Myr-Akt,expression
R12109 T18259 T18258 themeOf phosphorylation,required