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PMC:3585731 / 36021-37013 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T16762 783-792 Regulation denotes autocrine
T16761 649-661 Positive_regulation denotes upregulation
T16760 629-638 Regulation denotes dependent
T16759 558-566 Positive_regulation denotes response
T16758 530-544 Phosphorylation denotes phosphorylated
T16757 490-500 Gene_expression denotes expressing
T16756 457-466 Negative_regulation denotes knockdown
T16755 338-346 Positive_regulation denotes response
T16754 319-334 Transcription denotes mRNA production
T16753 305-313 Positive_regulation denotes restored
T16752 241-251 Gene_expression denotes Expression
T16751 126-134 Negative_regulation denotes deletion
T16737 793-797 Protein denotes TNFα
T16736 639-643 Protein denotes TNFα
T16735 624-628 Protein denotes RIP1
T16734 570-574 Protein denotes TNFα
T16733 520-524 Protein denotes Akt2
T16732 512-516 Protein denotes Akt1
T16731 350-354 Protein denotes TNFα
T16730 314-318 Protein denotes TNFα
T16729 222-226 Protein denotes TNFα
R11137 T16730 T16754 themeOf TNFα,mRNA production
R11138 T16731 T16754 themeOf TNFα,mRNA production
R11139 T16732 T16757 themeOf Akt1,expressing
R11140 T16733 T16758 themeOf Akt2,phosphorylated
R11141 T16735 T16760 causeOf RIP1,dependent
R11142 T16736 T16761 themeOf TNFα,upregulation
R11147 T16754 T16753 themeOf mRNA production,restored
R11148 T16761 T16760 themeOf upregulation,dependent

2_test

Id Subject Object Predicate Lexical cue
23469174-17210696-90505453 162-164 17210696 denotes 40

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T17247 517-519 CC denotes or
T17320 989-991 FW denotes se
T17319 985-988 FW denotes per
T17318 979-984 NN denotes death
T17317 974-978 NN denotes cell
T17316 970-973 CC denotes and
T17315 959-969 NN denotes conditions
T17314 947-958 JJ denotes necroptotic
T17313 941-946 IN denotes under
T17312 931-940 NN denotes signaling
T17311 918-930 JJ denotes inflammatory
T17310 905-917 JJ denotes Akt-mediated
T17309 897-904 IN denotes between
T17308 881-896 NN denotes differentiation
T17307 870-880 JJ denotes unexpected
T17306 867-869 DT denotes an
T17305 856-866 VB denotes indicating
T17304 854-855 -COMMA- denotes ,
T17303 849-854 NN denotes death
T17302 844-848 NN denotes cell
T17301 832-843 JJ denotes necroptotic
T17300 829-831 IN denotes of
T17299 821-828 NN denotes absence
T17298 817-820 DT denotes the
T17297 814-816 IN denotes in
T17296 809-813 RB denotes even
T17295 807-808 -COMMA- denotes ,
T17294 798-807 NN denotes synthesis
T17293 793-797 NN denotes TNFα
T17292 783-792 JJ denotes autocrine
T17291 779-782 IN denotes for
T17290 770-778 JJ denotes critical
T17289 767-769 VB denotes is
T17288 758-766 NN denotes activity
T17287 754-757 NN denotes Akt
T17286 749-753 IN denotes that
T17285 742-748 NN denotes notion
T17284 738-741 DT denotes the
T17283 730-737 VB denotes support
T17282 722-729 RB denotes further
T17281 717-721 NN denotes data
T17280 711-716 DT denotes These
T17279 708-709 -RRB- denotes )
T17278 706-708 NN denotes 8H
T17277 701-705 NNP denotes Fig.
T17276 700-701 -LRB- denotes (
T17275 689-699 NN denotes conditions
T17274 677-688 JJ denotes necroptotic
T17273 671-676 IN denotes under
T17272 662-670 VB denotes occurred
T17271 649-661 NN denotes upregulation
T17270 644-648 NN denotes mRNA
T17269 639-643 NN denotes TNFα
T17268 624-638 JJ denotes RIP1-dependent
T17267 617-623 JJ denotes robust
T17266 611-616 NN denotes cases
T17265 606-610 DT denotes both
T17264 603-605 IN denotes in
T17263 599-602 CC denotes and
T17262 597-598 -RRB- denotes )
T17261 594-597 NN denotes S9E
T17260 589-593 NN denotes Fig.
T17259 588-589 -LRB- denotes (
T17258 579-587 NN denotes zVAD.fmk
T17257 575-578 CC denotes and
T17256 570-574 NN denotes TNFα
T17255 567-569 TO denotes to
T17254 558-566 NN denotes response
T17253 555-557 IN denotes in
T17252 548-554 NN denotes Thr308
T17251 545-547 IN denotes on
T17250 530-544 VB denotes phosphorylated
T17249 525-529 VB denotes were
T17248 520-524 NN denotes Akt2
T17246 512-516 NN denotes Akt1
T17245 501-511 JJ denotes endogenous
T17244 490-500 VB denotes expressing
T17243 478-489 NN denotes fibroblasts
T17242 473-477 NN denotes lung
T17241 471-472 -COMMA- denotes ,
T17240 467-471 NN denotes data
T17239 457-466 JJ denotes knockdown
T17238 453-456 NN denotes Akt
T17237 445-452 JJ denotes earlier
T17236 441-444 PRP-DOLLAR- denotes our
T17235 436-440 IN denotes with
T17234 425-435 JJ denotes Consistent
T17233 422-423 -RRB- denotes )
T17232 419-422 NN denotes S9D
T17231 414-418 NN denotes Fig.
T17230 413-414 -LRB- denotes (
T17229 407-412 NN denotes death
T17228 402-406 NN denotes cell
T17227 386-401 JJ denotes re-establishing
T17226 378-385 IN denotes without
T17225 376-377 -RRB- denotes )
T17224 374-376 NN denotes 8G
T17223 369-373 NNP denotes Fig.
T17222 368-369 -LRB- denotes (
T17221 359-367 NN denotes zVAD.fmk
T17220 355-358 CC denotes and
T17219 350-354 NN denotes TNFα
T17218 347-349 TO denotes to
T17217 338-346 NN denotes response
T17216 335-337 IN denotes in
T17215 324-334 NN denotes production
T17214 319-323 NN denotes mRNA
T17213 314-318 NN denotes TNFα
T17212 305-313 VB denotes restored
T17211 299-304 NN denotes cells
T17210 293-298 DT denotes these
T17209 290-292 IN denotes in
T17208 288-289 -RRB- denotes )
T17207 281-288 NN denotes Myr-Akt
T17206 280-281 -LRB- denotes (
T17205 276-279 NN denotes Akt
T17204 269-275 JJ denotes active
T17203 255-268 RB denotes catalytically
T17202 252-254 IN denotes of
T17201 241-251 NN denotes Expression
T17200 231-239 NN denotes zVAD.fmk
T17199 227-230 CC denotes and
T17198 222-226 NN denotes TNFα
T17197 219-221 IN denotes of
T17196 210-218 NN denotes addition
T17195 206-209 DT denotes the
T17194 203-205 IN denotes by
T17193 195-202 VB denotes induced
T17192 189-194 NN denotes death
T17191 184-188 NN denotes cell
T17190 181-183 TO denotes to
T17189 171-180 JJ denotes resistant
T17188 166-170 VB denotes were
T17187 164-165 -RRB- denotes ]
T17186 162-164 CD denotes 40
T17185 161-162 -LRB- denotes [
T17184 152-160 NN denotes isoforms
T17183 148-151 NN denotes Akt
T17182 142-147 CD denotes three
T17181 138-141 DT denotes all
T17180 135-137 IN denotes of
T17179 126-134 NN denotes deletion
T17178 120-125 IN denotes after
T17177 112-119 VB denotes survive
T17176 109-111 TO denotes to
T17175 100-108 VB denotes selected
T17174 88-99 NN denotes fibroblasts
T17173 83-87 NN denotes Lung
T17172 70-81 NN denotes fibroblasts
T17171 65-69 NN denotes lung
T17170 59-64 NN denotes mouse
T17169 56-58 IN denotes in
T17168 44-55 NN denotes necroptosis
T17167 41-43 IN denotes in
T17166 37-40 NN denotes Akt
T17165 34-36 IN denotes of
T17164 29-33 NN denotes role
T17163 25-28 DT denotes the
T17162 22-24 IN denotes at
T17161 17-21 VB denotes look
T17160 14-16 TO denotes to
T17159 8-13 VB denotes chose
T17158 3-7 RB denotes next
T17157 0-2 PRP denotes We
R11400 T17157 T17159 arg1Of We,chose
R11401 T17157 T17161 arg1Of We,look
R11402 T17159 T17158 arg1Of chose,next
R11403 T17161 T17159 arg2Of look,chose
R11404 T17161 T17160 arg1Of look,to
R11405 T17161 T17162 arg1Of look,at
R11406 T17164 T17162 arg2Of role,at
R11407 T17164 T17163 arg1Of role,the
R11408 T17164 T17165 arg1Of role,of
R11409 T17164 T17167 arg1Of role,in
R11410 T17164 T17169 arg1Of role,in
R11411 T17166 T17165 arg2Of Akt,of
R11412 T17168 T17167 arg2Of necroptosis,in
R11413 T17172 T17169 arg2Of fibroblasts,in
R11414 T17172 T17170 arg1Of fibroblasts,mouse
R11415 T17172 T17171 arg1Of fibroblasts,lung
R11416 T17174 T17173 arg1Of fibroblasts,Lung
R11417 T17174 T17175 arg2Of fibroblasts,selected
R11418 T17174 T17177 arg1Of fibroblasts,survive
R11419 T17174 T17188 arg1Of fibroblasts,were
R11420 T17174 T17189 arg1Of fibroblasts,resistant
R11421 T17177 T17175 arg3Of survive,selected
R11422 T17177 T17176 arg1Of survive,to
R11423 T17177 T17178 arg1Of survive,after
R11424 T17179 T17178 arg2Of deletion,after
R11425 T17179 T17180 arg1Of deletion,of
R11426 T17184 T17180 arg2Of isoforms,of
R11427 T17184 T17181 arg1Of isoforms,all
R11428 T17184 T17182 arg1Of isoforms,three
R11429 T17184 T17183 arg1Of isoforms,Akt
R11430 T17184 T17185 arg1Of isoforms,[
R11431 T17186 T17185 arg2Of 40,[
R11432 T17187 T17185 arg3Of ],[
R11433 T17189 T17188 arg2Of resistant,were
R11434 T17189 T17190 arg1Of resistant,to
R11435 T17192 T17190 arg2Of death,to
R11436 T17192 T17191 arg1Of death,cell
R11437 T17192 T17193 arg2Of death,induced
R11438 T17196 T17193 arg1Of addition,induced
R11439 T17196 T17194 arg2Of addition,by
R11440 T17196 T17195 arg1Of addition,the
R11441 T17196 T17197 arg1Of addition,of
R11442 T17198 T17199 arg1Of TNFα,and
R11443 T17199 T17197 arg2Of and,of
R11444 T17200 T17199 arg2Of zVAD.fmk,and
R11445 T17201 T17202 arg1Of Expression,of
R11446 T17201 T17209 arg1Of Expression,in
R11447 T17201 T17212 arg1Of Expression,restored
R11448 T17204 T17203 arg1Of active,catalytically
R11449 T17205 T17202 arg2Of Akt,of
R11450 T17205 T17204 arg1Of Akt,active
R11451 T17205 T17206 arg1Of Akt,(
R11452 T17207 T17206 arg2Of Myr-Akt,(
R11453 T17208 T17206 arg3Of ),(
R11454 T17211 T17209 arg2Of cells,in
R11455 T17211 T17210 arg1Of cells,these
R11456 T17212 T17216 arg1Of restored,in
R11457 T17212 T17222 arg1Of restored,(
R11458 T17212 T17226 arg1Of restored,without
R11459 T17215 T17212 arg2Of production,restored
R11460 T17215 T17213 arg1Of production,TNFα
R11461 T17215 T17214 arg1Of production,mRNA
R11462 T17217 T17216 arg2Of response,in
R11463 T17217 T17218 arg1Of response,to
R11464 T17219 T17220 arg1Of TNFα,and
R11465 T17220 T17218 arg2Of and,to
R11466 T17221 T17220 arg2Of zVAD.fmk,and
R11467 T17224 T17222 arg2Of 8G,(
R11468 T17224 T17223 arg1Of 8G,Fig.
R11469 T17225 T17222 arg3Of ),(
R11470 T17229 T17226 arg2Of death,without
R11471 T17229 T17227 arg1Of death,re-establishing
R11472 T17229 T17228 arg1Of death,cell
R11473 T17229 T17230 arg1Of death,(
R11474 T17232 T17230 arg2Of S9D,(
R11475 T17232 T17231 arg1Of S9D,Fig.
R11476 T17233 T17230 arg3Of ),(
R11477 T17234 T17235 arg1Of Consistent,with
R11478 T17240 T17235 arg2Of data,with
R11479 T17240 T17236 arg1Of data,our
R11480 T17240 T17237 arg1Of data,earlier
R11481 T17240 T17238 arg1Of data,Akt
R11482 T17240 T17239 arg1Of data,knockdown
R11483 T17243 T17234 arg1Of fibroblasts,Consistent
R11484 T17243 T17242 arg1Of fibroblasts,lung
R11485 T17243 T17244 arg1Of fibroblasts,expressing
R11486 T17243 T17249 arg1Of fibroblasts,were
R11487 T17243 T17250 arg2Of fibroblasts,phosphorylated
R11488 T17246 T17247 arg1Of Akt1,or
R11489 T17247 T17244 arg2Of or,expressing
R11490 T17247 T17245 arg1Of or,endogenous
R11491 T17248 T17247 arg2Of Akt2,or
R11492 T17250 T17234 modOf phosphorylated,Consistent
R11493 T17250 T17241 arg1Of phosphorylated,","
R11494 T17250 T17249 arg2Of phosphorylated,were
R11495 T17250 T17251 arg1Of phosphorylated,on
R11496 T17250 T17253 arg1Of phosphorylated,in
R11497 T17250 T17263 arg1Of phosphorylated,and
R11498 T17252 T17251 arg2Of Thr308,on
R11499 T17254 T17253 arg2Of response,in
R11500 T17254 T17255 arg1Of response,to
R11501 T17256 T17257 arg1Of TNFα,and
R11502 T17257 T17255 arg2Of and,to
R11503 T17257 T17259 arg1Of and,(
R11504 T17258 T17257 arg2Of zVAD.fmk,and
R11505 T17261 T17259 arg2Of S9E,(
R11506 T17261 T17260 arg1Of S9E,Fig.
R11507 T17262 T17259 arg3Of ),(
R11508 T17266 T17264 arg2Of cases,in
R11509 T17266 T17265 arg1Of cases,both
R11510 T17271 T17267 arg1Of upregulation,robust
R11511 T17271 T17268 arg1Of upregulation,RIP1-dependent
R11512 T17271 T17269 arg1Of upregulation,TNFα
R11513 T17271 T17270 arg1Of upregulation,mRNA
R11514 T17271 T17272 arg1Of upregulation,occurred
R11515 T17272 T17263 arg2Of occurred,and
R11516 T17272 T17264 arg1Of occurred,in
R11517 T17272 T17273 arg1Of occurred,under
R11518 T17275 T17273 arg2Of conditions,under
R11519 T17275 T17274 arg1Of conditions,necroptotic
R11520 T17275 T17276 arg1Of conditions,(
R11521 T17278 T17276 arg2Of 8H,(
R11522 T17278 T17277 arg1Of 8H,Fig.
R11523 T17279 T17276 arg3Of ),(
R11524 T17281 T17280 arg1Of data,These
R11525 T17281 T17283 arg1Of data,support
R11526 T17283 T17282 arg1Of support,further
R11527 T17285 T17283 arg2Of notion,support
R11528 T17285 T17284 arg1Of notion,the
R11529 T17288 T17287 arg1Of activity,Akt
R11530 T17288 T17289 arg1Of activity,is
R11531 T17288 T17290 arg1Of activity,critical
R11532 T17289 T17285 arg2Of is,notion
R11533 T17289 T17286 arg1Of is,that
R11534 T17289 T17295 arg1Of is,","
R11535 T17289 T17297 arg1Of is,in
R11536 T17289 T17304 arg1Of is,","
R11537 T17289 T17305 modOf is,indicating
R11538 T17290 T17289 arg2Of critical,is
R11539 T17290 T17291 arg1Of critical,for
R11540 T17294 T17291 arg2Of synthesis,for
R11541 T17294 T17292 arg1Of synthesis,autocrine
R11542 T17294 T17293 arg1Of synthesis,TNFα
R11543 T17297 T17296 arg1Of in,even
R11544 T17297 T17298 arg1Of in,the
R11545 T17297 T17300 arg1Of in,of
R11546 T17299 T17297 arg2Of absence,in
R11547 T17303 T17297 arg3Of death,in
R11548 T17303 T17301 arg1Of death,necroptotic
R11549 T17303 T17302 arg1Of death,cell
R11550 T17308 T17305 arg2Of differentiation,indicating
R11551 T17308 T17306 arg1Of differentiation,an
R11552 T17308 T17307 arg1Of differentiation,unexpected
R11553 T17308 T17309 arg1Of differentiation,between
R11554 T17311 T17310 arg1Of inflammatory,Akt-mediated
R11555 T17312 T17311 arg1Of signaling,inflammatory
R11556 T17312 T17313 arg1Of signaling,under
R11557 T17312 T17316 arg1Of signaling,and
R11558 T17315 T17313 arg2Of conditions,under
R11559 T17315 T17314 arg1Of conditions,necroptotic
R11560 T17316 T17309 arg2Of and,between
R11561 T17318 T17316 arg2Of death,and
R11562 T17318 T17317 arg1Of death,cell
R11563 T17318 T17320 arg1Of death,se
R11564 T17320 T17319 arg1Of se,per

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T16892 793-797 Protein denotes TNFα
T16891 639-643 Protein denotes TNFα
T16890 624-628 Protein denotes RIP1
T16889 570-574 Protein denotes TNFα
T16888 520-524 Protein denotes Akt2
T16887 512-516 Protein denotes Akt1
T16886 350-354 Protein denotes TNFα
T16885 314-318 Protein denotes TNFα
T16884 222-226 Protein denotes TNFα

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T17426 624-628 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T17421 793-797 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T17420 639-643 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T17419 570-574 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T17418 350-354 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T17417 314-318 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T17416 222-226 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T17411 905-908 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T17410 754-757 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T17409 453-456 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T17408 285-288 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T17407 276-279 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T17406 148-151 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T17405 37-40 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T17398 905-908 http://www.uniprot.org/uniprot/P31751 denotes Akt
T17397 754-757 http://www.uniprot.org/uniprot/P31751 denotes Akt
T17396 453-456 http://www.uniprot.org/uniprot/P31751 denotes Akt
T17395 285-288 http://www.uniprot.org/uniprot/P31751 denotes Akt
T17394 276-279 http://www.uniprot.org/uniprot/P31751 denotes Akt
T17393 148-151 http://www.uniprot.org/uniprot/P31751 denotes Akt
T17392 37-40 http://www.uniprot.org/uniprot/P31751 denotes Akt
T17385 905-908 http://www.uniprot.org/uniprot/P31749 denotes Akt
T17384 754-757 http://www.uniprot.org/uniprot/P31749 denotes Akt
T17383 453-456 http://www.uniprot.org/uniprot/P31749 denotes Akt
T17382 285-288 http://www.uniprot.org/uniprot/P31749 denotes Akt
T17381 276-279 http://www.uniprot.org/uniprot/P31749 denotes Akt
T17380 148-151 http://www.uniprot.org/uniprot/P31749 denotes Akt
T17379 37-40 http://www.uniprot.org/uniprot/P31749 denotes Akt

UBERON-AE

Id Subject Object Predicate Lexical cue
T16825 473-477 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T16824 65-69 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung

GO-BP

Id Subject Object Predicate Lexical cue
T16925 184-202 http://purl.obolibrary.org/obo/GO_0071888 denotes cell death induced
T16924 184-202 http://purl.obolibrary.org/obo/GO_0043276 denotes cell death induced
T16923 798-807 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T16919 44-55 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T16914 44-55 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T16909 979-984 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T16908 849-854 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T16907 407-412 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T16906 189-194 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T16901 974-984 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T16900 844-854 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T16899 402-412 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T16898 184-194 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T16895 931-940 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling

GO-CC

Id Subject Object Predicate Lexical cue
T16933 974-978 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T16932 844-848 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T16931 402-406 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T16930 299-304 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T16837 711-992 Sentence denotes These data further support the notion that Akt activity is critical for autocrine TNFα synthesis, even in the absence of necroptotic cell death, indicating an unexpected differentiation between Akt-mediated inflammatory signaling under necroptotic conditions and cell death per se.
T16836 425-710 Sentence denotes Consistent with our earlier Akt knockdown data, lung fibroblasts expressing endogenous Akt1 or Akt2 were phosphorylated on Thr308 in response to TNFα and zVAD.fmk (Fig. S9E) and in both cases robust RIP1-dependent TNFα mRNA upregulation occurred under necroptotic conditions (Fig. 8H).
T16835 241-424 Sentence denotes Expression of catalytically active Akt (Myr-Akt) in these cells restored TNFα mRNA production in response to TNFα and zVAD.fmk (Fig. 8G) without re-establishing cell death (Fig. S9D).
T16834 83-240 Sentence denotes Lung fibroblasts selected to survive after deletion of all three Akt isoforms [40] were resistant to cell death induced by the addition of TNFα and zVAD.fmk.
T16833 0-82 Sentence denotes We next chose to look at the role of Akt in necroptosis in mouse lung fibroblasts.
T223 0-82 Sentence denotes We next chose to look at the role of Akt in necroptosis in mouse lung fibroblasts.
T224 83-240 Sentence denotes Lung fibroblasts selected to survive after deletion of all three Akt isoforms [40] were resistant to cell death induced by the addition of TNFα and zVAD.fmk.
T225 241-424 Sentence denotes Expression of catalytically active Akt (Myr-Akt) in these cells restored TNFα mRNA production in response to TNFα and zVAD.fmk (Fig. 8G) without re-establishing cell death (Fig. S9D).
T226 425-710 Sentence denotes Consistent with our earlier Akt knockdown data, lung fibroblasts expressing endogenous Akt1 or Akt2 were phosphorylated on Thr308 in response to TNFα and zVAD.fmk (Fig. S9E) and in both cases robust RIP1-dependent TNFα mRNA upregulation occurred under necroptotic conditions (Fig. 8H).
T227 711-992 Sentence denotes These data further support the notion that Akt activity is critical for autocrine TNFα synthesis, even in the absence of necroptotic cell death, indicating an unexpected differentiation between Akt-mediated inflammatory signaling under necroptotic conditions and cell death per se.

simple1

Id Subject Object Predicate Lexical cue
T16952 793-797 Protein denotes TNFα
T16951 639-643 Protein denotes TNFα
T16950 624-628 Protein denotes RIP1
T16949 570-574 Protein denotes TNFα
T16948 520-524 Protein denotes Akt2
T16947 512-516 Protein denotes Akt1
T16946 350-354 Protein denotes TNFα
T16945 314-318 Protein denotes TNFα
T16944 222-226 Protein denotes TNFα

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T17372 798-807 Gene_expression denotes synthesis
T17371 629-638 Positive_regulation denotes dependent
T17370 490-500 Gene_expression denotes expressing
T17369 649-661 Positive_regulation denotes upregulation
T17368 324-334 Transcription denotes production
T17367 305-313 Positive_regulation denotes restored
T17358 793-797 Protein denotes TNFα
T17357 639-643 Protein denotes TNFα
T17356 624-628 Protein denotes RIP1
T17355 570-574 Protein denotes TNFα
T17354 520-524 Protein denotes Akt2
T17353 512-516 Protein denotes Akt1
T17352 350-354 Protein denotes TNFα
T17351 314-318 Protein denotes TNFα
T17350 222-226 Protein denotes TNFα
R11572 T17351 T17368 themeOf TNFα,production
R11573 T17353 T17370 themeOf Akt1,expressing
R11574 T17354 T17370 themeOf Akt2,expressing
R11575 T17357 T17369 themeOf TNFα,upregulation
R11576 T17358 T17372 themeOf TNFα,synthesis
R11579 T17368 T17367 themeOf production,restored
R11580 T17369 T17371 themeOf upregulation,dependent

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T17906 798-807 Gene_expression denotes synthesis
T17905 770-778 Positive_regulation denotes critical
T17904 649-661 Positive_regulation denotes upregulation
T17903 629-638 Positive_regulation denotes dependent
T17902 490-500 Gene_expression denotes expressing
T17901 305-313 Negative_regulation denotes restored
T17900 359-367 Negative_regulation denotes zVAD.fmk
T17899 324-334 Transcription denotes production
T17891 793-797 Protein denotes TNFα
T17890 639-643 Protein denotes TNFα
T17889 624-628 Protein denotes RIP1
T17888 570-574 Protein denotes TNFα
T17887 520-524 Protein denotes Akt2
T17886 512-516 Protein denotes Akt1
T17885 350-354 Protein denotes TNFα
T17884 314-318 Protein denotes TNFα
T17883 222-226 Protein denotes TNFα
R12001 T17884 T17899 themeOf TNFα,production
R12002 T17885 T17900 themeOf TNFα,zVAD.fmk
R12003 T17886 T17902 themeOf Akt1,expressing
R12004 T17887 T17902 themeOf Akt2,expressing
R12005 T17889 T17903 causeOf RIP1,dependent
R12006 T17890 T17904 themeOf TNFα,upregulation
R12007 T17891 T17906 themeOf TNFα,synthesis
R12010 T17899 T17901 themeOf production,restored
R12011 T17904 T17903 themeOf upregulation,dependent
R12012 T17906 T17905 themeOf synthesis,critical

DLUT931

Id Subject Object Predicate Lexical cue
T17872 798-807 Gene_expression denotes synthesis
T17871 629-638 Positive_regulation denotes dependent
T17870 649-661 Positive_regulation denotes upregulation
T17869 530-544 Phosphorylation denotes phosphorylated
T17868 490-500 Gene_expression denotes expressing
T17867 305-313 Negative_regulation denotes restored
T17866 324-334 Transcription denotes production
T17856 793-797 Protein denotes TNFα
T17855 639-643 Protein denotes TNFα
T17854 624-628 Protein denotes RIP1
T17853 570-574 Protein denotes TNFα
T17852 520-524 Protein denotes Akt2
T17851 512-516 Protein denotes Akt1
T17850 350-354 Protein denotes TNFα
T17849 314-318 Protein denotes TNFα
T17848 222-226 Protein denotes TNFα
R11980 T17849 T17866 themeOf TNFα,production
R11981 T17851 T17868 themeOf Akt1,expressing
R11982 T17852 T17868 themeOf Akt2,expressing
R11983 T17853 T17869 themeOf TNFα,phosphorylated
R11984 T17854 T17871 causeOf RIP1,dependent
R11985 T17855 T17870 themeOf TNFα,upregulation
R11986 T17856 T17872 themeOf TNFα,synthesis
R11994 T17866 T17867 themeOf production,restored
R11995 T17870 T17871 themeOf upregulation,dependent

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T18108 478-524 Gene_expression denotes fibroblasts expressing endogenous Akt1 or Akt2
T18107 478-524 Gene_expression denotes fibroblasts expressing endogenous Akt1 or Akt2
T18102 617-661 Positive_regulation denotes robust RIP1-dependent TNFα mRNA upregulation
T18101 314-334 Gene_expression denotes TNFα mRNA production
T18097 905-969 Regulation denotes Akt-mediated inflammatory signaling under necroptotic conditions
T18094 231-239 Entity denotes zVAD.fmk
T18091 314-323 Protein denotes TNFα mRNA
T18089 281-288 Entity denotes Myr-Akt
T18085 749-757 Protein denotes that Akt
T18081 617-648 Protein denotes robust RIP1-dependent TNFα mRNA
T18078 269-289 Protein denotes active Akt (Myr-Akt)
T18076 579-587 Entity denotes zVAD.fmk
T18075 478-524 Entity denotes fibroblasts expressing endogenous Akt1 or Akt2
T18074 34-40 Protein denotes of Akt
T18072 589-592 Protein denotes Fig
T18071 148-151 Protein denotes Akt
T18068 905-917 Protein denotes Akt-mediated
T18065 779-808 Protein denotes for autocrine TNFα synthesis,
T18060 520-524 Protein denotes Akt2
T18059 281-288 Protein denotes Myr-Akt
T18054 548-554 Entity denotes Thr308
T18053 314-318 Protein denotes TNFα
T18050 83-165 Entity denotes Lung fibroblasts selected to survive after deletion of all three Akt isoforms [40]
T18048 59-81 Entity denotes mouse lung fibroblasts
T18047 453-456 Protein denotes Akt
T18046 639-643 Protein denotes TNFα
T18045 369-372 Protein denotes Fig
T18043 501-516 Protein denotes endogenous Akt1
T18041 293-304 Entity denotes these cells
T18037 222-226 Protein denotes TNFα
T18036 414-417 Protein denotes Fig
T18034 350-354 Protein denotes TNFα
T18033 570-574 Protein denotes TNFα
T18032 359-367 Entity denotes zVAD.fmk
T18031 624-638 Protein denotes RIP1-dependent
R12064 T18043 T18107 themeOf endogenous Akt1,fibroblasts expressing endogenous Akt1 or Akt2
R12070 T18060 T18108 themeOf Akt2,fibroblasts expressing endogenous Akt1 or Akt2
R12073 T18068 T18097 causeOf Akt-mediated,Akt-mediated inflammatory signaling under necroptotic conditions
R12075 T18081 T18102 themeOf robust RIP1-dependent TNFα mRNA,robust RIP1-dependent TNFα mRNA upregulation
R12078 T18091 T18101 themeOf TNFα mRNA,TNFα mRNA production

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T17810 989-991 FW denotes se
T17809 985-988 IN denotes per
T17808 979-984 NN denotes death
T17807 974-978 NN denotes cell
T17806 970-973 CC denotes and
T17805 959-969 NNS denotes conditions
T17804 947-958 JJ denotes necroptotic
T17803 941-946 IN denotes under
T17802 931-940 VBG denotes signaling
T17801 918-930 JJ denotes inflammatory
T17800 905-917 JJ denotes Akt-mediated
T17799 897-904 IN denotes between
T17798 881-896 NN denotes differentiation
T17797 870-880 JJ denotes unexpected
T17796 867-869 DT denotes an
T17795 856-866 VBG denotes indicating
T17794 854-855 , denotes ,
T17793 849-854 NN denotes death
T17792 844-848 NN denotes cell
T17791 832-843 JJ denotes necroptotic
T17790 829-831 IN denotes of
T17789 821-828 NN denotes absence
T17788 817-820 DT denotes the
T17787 814-816 IN denotes in
T17786 809-813 RB denotes even
T17785 807-808 , denotes ,
T17784 798-807 NN denotes synthesis
T17783 793-797 NNP denotes TNFα
T17782 783-792 NN denotes autocrine
T17781 779-782 IN denotes for
T17780 770-778 JJ denotes critical
T17779 767-769 VBZ denotes is
T17778 758-766 NN denotes activity
T17777 754-757 NNP denotes Akt
T17776 749-753 IN denotes that
T17775 742-748 NN denotes notion
T17774 738-741 DT denotes the
T17773 730-737 NN denotes support
T17772 722-729 JJ denotes further
T17771 717-721 NNS denotes data
T17770 711-716 DT denotes These
T17769 709-710 . denotes .
T17768 708-709 -RRB- denotes )
T17767 706-708 NNP denotes 8H
T17766 701-705 NNP denotes Fig.
T17765 700-701 -LRB- denotes (
T17764 689-699 NNS denotes conditions
T17763 677-688 JJ denotes necroptotic
T17762 671-676 IN denotes under
T17761 662-670 VBD denotes occurred
T17760 649-661 NN denotes upregulation
T17759 644-648 NNP denotes mRNA
T17758 639-643 NNP denotes TNFα
T17757 624-638 NN denotes RIP1-dependent
T17756 617-623 JJ denotes robust
T17755 611-616 NNS denotes cases
T17754 606-610 DT denotes both
T17753 603-605 IN denotes in
T17752 599-602 CC denotes and
T17751 597-598 -RRB- denotes )
T17750 594-597 CD denotes S9E
T17749 592-593 . denotes .
T17748 589-592 NNP denotes Fig
T17747 588-589 -LRB- denotes (
T17746 579-587 NNP denotes zVAD.fmk
T17745 575-578 CC denotes and
T17744 570-574 NNP denotes TNFα
T17743 567-569 TO denotes to
T17742 558-566 NN denotes response
T17741 555-557 IN denotes in
T17740 548-554 NNP denotes Thr308
T17739 545-547 IN denotes on
T17738 530-544 VBN denotes phosphorylated
T17737 525-529 VBD denotes were
T17736 520-524 JJ denotes Akt2
T17735 517-519 CC denotes or
T17701 324-334 NN denotes production
T17700 319-323 NNP denotes mRNA
T17699 314-318 NNP denotes TNFα
T17698 305-313 VBD denotes restored
T17697 299-304 NNS denotes cells
T17696 293-298 DT denotes these
T17695 290-292 IN denotes in
T17694 288-289 -RRB- denotes )
T17693 281-288 NNP denotes Myr-Akt
T17692 280-281 -LRB- denotes (
T17691 276-279 NNP denotes Akt
T17690 269-275 JJ denotes active
T17689 255-268 RB denotes catalytically
T17688 252-254 IN denotes of
T17687 241-251 NN denotes Expression
T17686 239-240 . denotes .
T17685 231-239 NNP denotes zVAD.fmk
T17684 227-230 CC denotes and
T17683 222-226 NNP denotes TNFα
T17682 219-221 IN denotes of
T17681 210-218 NN denotes addition
T17680 206-209 DT denotes the
T17679 203-205 IN denotes by
T17678 195-202 VBN denotes induced
T17677 189-194 NN denotes death
T17676 184-188 NN denotes cell
T17675 181-183 TO denotes to
T17674 171-180 JJ denotes resistant
T17673 166-170 VBD denotes were
T17672 164-165 NNP denotes ]
T17671 162-164 CD denotes 40
T17670 161-162 NNP denotes [
T17669 152-160 VBZ denotes isoforms
T17668 148-151 NNP denotes Akt
T17667 142-147 CD denotes three
T17666 138-141 DT denotes all
T17665 135-137 IN denotes of
T17664 126-134 NN denotes deletion
T17663 120-125 IN denotes after
T17662 112-119 VB denotes survive
T17661 109-111 TO denotes to
T17660 100-108 VBN denotes selected
T17659 88-99 NNS denotes fibroblasts
T17658 83-87 NN denotes Lung
T17657 81-82 . denotes .
T17656 70-81 NNS denotes fibroblasts
T17655 65-69 NN denotes lung
T17654 59-64 NN denotes mouse
T17653 56-58 IN denotes in
T17652 44-55 NN denotes necroptosis
T17651 41-43 IN denotes in
T17650 37-40 NNP denotes Akt
T17649 34-36 IN denotes of
T17648 29-33 NN denotes role
T17647 25-28 DT denotes the
T17646 22-24 IN denotes at
T17645 17-21 VB denotes look
T17644 14-16 TO denotes to
T17643 8-13 VBD denotes chose
T17642 3-7 JJ denotes next
T17641 0-2 PRP denotes We
T17734 512-516 JJ denotes Akt1
T17733 501-511 JJ denotes endogenous
T17732 490-500 VBG denotes expressing
T17731 478-489 NNS denotes fibroblasts
T17730 473-477 NN denotes lung
T17729 471-472 , denotes ,
T17728 467-471 NNS denotes data
T17727 457-466 JJ denotes knockdown
T17726 453-456 NNP denotes Akt
T17711 376-377 -RRB- denotes )
T17710 374-376 NNP denotes 8G
T17709 369-373 NNP denotes Fig.
T17708 368-369 -LRB- denotes (
T17707 359-367 NNP denotes zVAD.fmk
T17706 355-358 CC denotes and
T17705 350-354 NNP denotes TNFα
T17704 347-349 TO denotes to
T17703 338-346 NN denotes response
T17702 335-337 IN denotes in
T17719 419-422 CD denotes S9D
T17718 417-418 . denotes .
T17717 414-417 NNP denotes Fig
T17716 413-414 -LRB- denotes (
T17715 407-412 NN denotes death
T17714 402-406 NN denotes cell
T17713 386-401 VBG denotes re-establishing
T17712 378-385 IN denotes without
T17725 445-452 JJR denotes earlier
T17724 441-444 PRP$ denotes our
T17723 436-440 IN denotes with
T17722 425-435 JJ denotes Consistent
T17721 423-424 . denotes .
T17720 422-423 -RRB- denotes )
T17811 991-992 . denotes .
R11795 T17641 T17643 nsubj We,chose
R11796 T17642 T17643 advmod next,chose
R11797 T17643 T17643 ROOT chose,chose
R11798 T17644 T17645 aux to,look
R11799 T17645 T17643 xcomp look,chose
R11800 T17646 T17645 prep at,look
R11801 T17647 T17648 det the,role
R11802 T17648 T17646 pobj role,at
R11803 T17649 T17648 prep of,role
R11804 T17650 T17649 pobj Akt,of
R11805 T17651 T17648 prep in,role
R11806 T17652 T17651 pobj necroptosis,in
R11807 T17653 T17652 prep in,necroptosis
R11808 T17654 T17656 compound mouse,fibroblasts
R11809 T17655 T17656 compound lung,fibroblasts
R11810 T17656 T17653 pobj fibroblasts,in
R11811 T17657 T17643 punct .,chose
R11812 T17658 T17659 compound Lung,fibroblasts
R11813 T17659 T17673 nsubj fibroblasts,were
R11814 T17660 T17659 acl selected,fibroblasts
R11815 T17661 T17662 aux to,survive
R11816 T17662 T17660 xcomp survive,selected
R11817 T17663 T17662 prep after,survive
R11818 T17664 T17663 pobj deletion,after
R11819 T17665 T17664 prep of,deletion
R11820 T17666 T17665 pobj all,of
R11821 T17667 T17669 nummod three,isoforms
R11822 T17668 T17669 nsubj Akt,isoforms
R11823 T17669 T17673 nsubj isoforms,were
R11824 T17670 T17672 nmod [,]
R11825 T17671 T17672 nummod 40,]
R11826 T17672 T17673 nsubj ],were
R11827 T17673 T17673 ROOT were,were
R11828 T17674 T17673 acomp resistant,were
R11829 T17675 T17674 prep to,resistant
R11830 T17676 T17677 compound cell,death
R11831 T17677 T17675 pobj death,to
R11832 T17678 T17677 acl induced,death
R11833 T17679 T17678 agent by,induced
R11834 T17680 T17681 det the,addition
R11835 T17681 T17679 pobj addition,by
R11836 T17682 T17681 prep of,addition
R11837 T17683 T17682 pobj TNFα,of
R11838 T17684 T17683 cc and,TNFα
R11839 T17685 T17683 conj zVAD.fmk,TNFα
R11840 T17686 T17673 punct .,were
R11841 T17687 T17698 nsubj Expression,restored
R11842 T17688 T17687 prep of,Expression
R11843 T17689 T17690 advmod catalytically,active
R11844 T17690 T17691 amod active,Akt
R11845 T17691 T17688 pobj Akt,of
R11846 T17692 T17693 punct (,Myr-Akt
R11847 T17693 T17691 appos Myr-Akt,Akt
R11848 T17694 T17691 punct ),Akt
R11849 T17695 T17687 prep in,Expression
R11850 T17696 T17697 det these,cells
R11851 T17697 T17695 pobj cells,in
R11852 T17698 T17698 ROOT restored,restored
R11853 T17699 T17700 compound TNFα,mRNA
R11854 T17700 T17701 compound mRNA,production
R11855 T17701 T17698 dobj production,restored
R11856 T17702 T17698 prep in,restored
R11857 T17703 T17702 pobj response,in
R11858 T17704 T17703 prep to,response
R11859 T17705 T17704 pobj TNFα,to
R11860 T17706 T17705 cc and,TNFα
R11861 T17707 T17705 conj zVAD.fmk,TNFα
R11862 T17708 T17710 punct (,8G
R11863 T17709 T17710 compound Fig.,8G
R11864 T17710 T17707 appos 8G,zVAD.fmk
R11865 T17711 T17707 punct ),zVAD.fmk
R11866 T17712 T17698 prep without,restored
R11867 T17713 T17712 pcomp re-establishing,without
R11868 T17714 T17715 compound cell,death
R11869 T17715 T17713 dobj death,re-establishing
R11870 T17716 T17717 punct (,Fig
R11871 T17717 T17715 appos Fig,death
R11872 T17718 T17698 punct .,restored
R11873 T17719 T17719 ROOT S9D,S9D
R11874 T17720 T17719 punct ),S9D
R11875 T17721 T17719 punct .,S9D
R11876 T17722 T17722 ROOT Consistent,Consistent
R11877 T17723 T17722 prep with,Consistent
R11878 T17724 T17728 poss our,data
R11879 T17725 T17728 amod earlier,data
R11880 T17726 T17728 compound Akt,data
R11881 T17727 T17728 compound knockdown,data
R11882 T17728 T17723 pobj data,with
R11883 T17729 T17728 punct ",",data
R11884 T17730 T17731 compound lung,fibroblasts
R11885 T17731 T17728 conj fibroblasts,data
R11886 T17732 T17723 pcomp expressing,with
R11887 T17733 T17734 amod endogenous,Akt1
R11888 T17734 T17738 nsubjpass Akt1,phosphorylated
R11889 T17735 T17734 cc or,Akt1
R11890 T17736 T17734 conj Akt2,Akt1
R11891 T17737 T17738 auxpass were,phosphorylated
R11892 T17738 T17738 ROOT phosphorylated,phosphorylated
R11893 T17739 T17738 prep on,phosphorylated
R11894 T17740 T17739 pobj Thr308,on
R11895 T17741 T17738 prep in,phosphorylated
R11896 T17742 T17741 pobj response,in
R11897 T17743 T17742 prep to,response
R11898 T17744 T17743 pobj TNFα,to
R11899 T17745 T17744 cc and,TNFα
R11900 T17746 T17744 conj zVAD.fmk,TNFα
R11901 T17747 T17748 punct (,Fig
R11902 T17748 T17746 appos Fig,zVAD.fmk
R11903 T17749 T17738 punct .,phosphorylated
R11904 T17750 T17750 ROOT S9E,S9E
R11905 T17751 T17750 punct ),S9E
R11906 T17752 T17750 cc and,S9E
R11907 T17753 T17761 prep in,occurred
R11908 T17754 T17755 det both,cases
R11909 T17755 T17753 pobj cases,in
R11910 T17756 T17757 amod robust,RIP1-dependent
R11911 T17757 T17760 compound RIP1-dependent,upregulation
R11912 T17758 T17760 compound TNFα,upregulation
R11913 T17759 T17760 compound mRNA,upregulation
R11914 T17760 T17761 nsubj upregulation,occurred
R11915 T17761 T17750 conj occurred,S9E
R11916 T17762 T17761 prep under,occurred
R11917 T17763 T17764 amod necroptotic,conditions
R11918 T17764 T17762 pobj conditions,under
R11919 T17765 T17767 punct (,8H
R11920 T17766 T17767 compound Fig.,8H
R11921 T17767 T17761 parataxis 8H,occurred
R11922 T17768 T17767 punct ),8H
R11923 T17769 T17761 punct .,occurred
R11924 T17770 T17771 det These,data
R11925 T17771 T17773 nsubj data,support
R11926 T17772 T17773 advmod further,support
R11927 T17773 T17773 ROOT support,support
R11928 T17774 T17775 det the,notion
R11929 T17775 T17773 dobj notion,support
R11930 T17776 T17779 mark that,is
R11931 T17777 T17778 compound Akt,activity
R11932 T17778 T17779 nsubj activity,is
R11933 T17779 T17775 acl is,notion
R11934 T17780 T17779 acomp critical,is
R11935 T17781 T17780 prep for,critical
R11936 T17782 T17784 compound autocrine,synthesis
R11937 T17783 T17784 compound TNFα,synthesis
R11938 T17784 T17781 pobj synthesis,for
R11939 T17785 T17779 punct ",",is
R11940 T17786 T17787 advmod even,in
R11941 T17787 T17779 prep in,is
R11942 T17788 T17789 det the,absence
R11943 T17789 T17787 pobj absence,in
R11944 T17790 T17789 prep of,absence
R11945 T17791 T17793 amod necroptotic,death
R11946 T17792 T17793 compound cell,death
R11947 T17793 T17790 pobj death,of
R11948 T17794 T17779 punct ",",is
R11949 T17795 T17779 advcl indicating,is
R11950 T17796 T17798 det an,differentiation
R11951 T17797 T17798 amod unexpected,differentiation
R11952 T17798 T17795 dobj differentiation,indicating
R11953 T17799 T17798 prep between,differentiation
R11954 T17800 T17802 amod Akt-mediated,signaling
R11955 T17801 T17802 amod inflammatory,signaling
R11956 T17802 T17799 pobj signaling,between
R11957 T17803 T17798 prep under,differentiation
R11958 T17804 T17805 amod necroptotic,conditions
R11959 T17805 T17803 pobj conditions,under
R11960 T17806 T17805 cc and,conditions
R11961 T17807 T17808 compound cell,death
R11962 T17808 T17798 conj death,differentiation
R11963 T17809 T17798 prep per,differentiation
R11964 T17810 T17809 pobj se,per
R11965 T17811 T17773 punct .,support

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T17959 490-500 Gene_expression denotes expressing
T17958 490-500 Gene_expression denotes expressing
T17957 639-648 Protein denotes TNFα mRNA
T17956 624-628 Protein denotes RIP1
T17955 594-597 Protein denotes S9E
T17950 520-524 Protein denotes Akt2
T17949 501-516 Protein denotes endogenous Akt1
T17948 324-334 Gene_expression denotes production
T17947 241-251 Gene_expression denotes Expression
T17946 241-251 Gene_expression denotes Expression
T17945 241-251 Gene_expression denotes Expression
T17944 419-422 Protein denotes S9D
T17943 414-417 Protein denotes Fig
T17942 369-376 Protein denotes Fig. 8G
T17941 359-367 Protein denotes zVAD.fmk
T17940 350-354 Protein denotes TNFα
T17939 314-323 Protein denotes TNFα mRNA
T17938 285-288 Protein denotes Akt
T17937 281-284 Protein denotes Myr
T17936 276-279 Protein denotes Akt
T17935 231-239 Protein denotes zVAD.fmk
T17934 222-226 Protein denotes TNFα
T17933 148-151 Protein denotes Akt
T17932 37-40 Protein denotes Akt
T17954 589-592 Protein denotes Fig
T17953 579-587 Protein denotes zVAD.fmk
T17952 570-574 Protein denotes TNFα
T17951 548-554 Protein denotes Thr308
T17968 798-807 Gene_expression denotes synthesis
T17967 783-797 Protein denotes autocrine TNFα
T17966 754-757 Protein denotes Akt
T17965 649-661 Positive_regulation denotes upregulation
T17964 530-544 Phosphorylation denotes phosphorylated
T17963 530-544 Phosphorylation denotes phosphorylated
T17962 530-544 Phosphorylation denotes phosphorylated
T17961 530-544 Phosphorylation denotes phosphorylated
T17960 530-544 Phosphorylation denotes phosphorylated
R12024 T17936 T17945 themeOf Akt,Expression
R12025 T17937 T17946 themeOf Myr,Expression
R12026 T17938 T17947 themeOf Akt,Expression
R12027 T17939 T17948 themeOf TNFα mRNA,production
R12028 T17949 T17958 themeOf endogenous Akt1,expressing
R12029 T17950 T17959 themeOf Akt2,expressing
R12030 T17951 T17960 themeOf Thr308,phosphorylated
R12031 T17952 T17961 themeOf TNFα,phosphorylated
R12032 T17953 T17962 themeOf zVAD.fmk,phosphorylated
R12033 T17954 T17963 themeOf Fig,phosphorylated
R12034 T17955 T17964 themeOf S9E,phosphorylated
R12035 T17957 T17965 themeOf TNFα mRNA,upregulation
R12036 T17967 T17968 themeOf autocrine TNFα,synthesis

test3

Id Subject Object Predicate Lexical cue
T16823 798-807 Gene_expression denotes synthesis
T16822 793-797 Protein denotes TNFα
T16821 783-792 Regulation denotes autocrine
T16820 649-661 Positive_regulation denotes upregulation
T16819 639-643 Protein denotes TNFα
T16818 629-638 Regulation denotes dependent
T16817 624-628 Protein denotes RIP1
T16816 570-574 Protein denotes TNFα
T16815 530-544 Phosphorylation denotes phosphorylated
T16814 520-524 Protein denotes Akt2
T16813 512-516 Protein denotes Akt1
T16812 490-500 Gene_expression denotes expressing
T16811 457-466 Negative_regulation denotes knockdown
T16810 350-354 Protein denotes TNFα
T16809 335-349 Positive_regulation denotes in response to
T16808 319-334 Transcription denotes mRNA production
T16807 314-318 Protein denotes TNFα
T16806 269-275 Positive_regulation denotes active
T16805 222-226 Protein denotes TNFα
T16804 195-202 Positive_regulation denotes induced
T16803 126-134 Negative_regulation denotes deletion
T16781 793-797 Protein denotes TNFα
T16780 639-643 Protein denotes TNFα
T16779 624-628 Protein denotes RIP1
T16778 570-574 Protein denotes TNFα
T16777 520-524 Protein denotes Akt2
T16776 512-516 Protein denotes Akt1
T16775 350-354 Protein denotes TNFα
T16774 314-318 Protein denotes TNFα
T16773 222-226 Protein denotes TNFα
R11158 T16803 T16804 themeOf deletion,induced
R11159 T16807 T16808 themeOf TNFα,mRNA production
R11160 T16808 T16809 themeOf mRNA production,in response to
R11161 T16810 T16809 causeOf TNFα,in response to
R11162 T16813 T16815 themeOf Akt1,phosphorylated
R11163 T16813 T16812 themeOf Akt1,expressing
R11164 T16814 T16815 themeOf Akt2,phosphorylated
R11165 T16814 T16812 themeOf Akt2,expressing
R11166 T16817 T16818 causeOf RIP1,dependent
R11167 T16819 T16820 themeOf TNFα,upregulation
R11168 T16820 T16818 themeOf upregulation,dependent
R11169 T16822 T16823 themeOf TNFα,synthesis
R11170 T16823 T16821 themeOf synthesis,autocrine