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PMC:3585731 / 311-732 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T26 371-386 Phosphorylation denotes phosphorylation
T25 341-350 Regulation denotes dependent
T24 321-330 Positive_regulation denotes activated
T23 282-292 Gene_expression denotes production
T22 269-273 Regulation denotes role
T16 336-340 Protein denotes RIP1
T15 277-281 Protein denotes TNFα
T14 164-168 Protein denotes RIP1
T13 132-162 Protein denotes receptor interacting protein-1
R5 T23 T22 themeOf production,role
R1 T14 T13 equivalentTo RIP1,receptor interacting protein-1
R2 T15 T23 themeOf TNFα,production

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T256 413-417 DT denotes this
T255 411-412 -COMMA- denotes ,
T254 406-411 NN denotes cells
T253 401-405 NN denotes L929
T252 398-400 IN denotes In
T251 390-396 NN denotes Thr308
T250 387-389 IN denotes on
T249 371-386 NN denotes phosphorylation
T248 367-370 PRP-DOLLAR- denotes its
T247 359-366 IN denotes through
T246 351-358 NN denotes fashion
T245 341-350 JJ denotes dependent
T244 336-340 NN denotes RIP1
T243 334-335 DT denotes a
T242 331-333 IN denotes in
T241 321-330 VB denotes activated
T240 318-320 VB denotes is
T239 314-317 NN denotes Akt
T238 312-313 -COMMA- denotes ,
T237 301-312 NN denotes necroptosis
T236 294-300 IN denotes During
T235 282-292 NN denotes production
T234 277-281 NN denotes TNFα
T233 274-276 IN denotes in
T232 269-273 NN denotes role
T231 265-268 JJ denotes key
T230 263-264 DT denotes a
T229 257-262 VB denotes plays
T228 253-256 CC denotes and
T227 247-252 NN denotes cells
T226 242-246 NN denotes L929
T225 239-241 IN denotes in
T224 227-238 NN denotes necroptosis
T223 223-226 IN denotes for
T222 214-222 JJ denotes critical
T221 211-213 VB denotes is
T220 202-210 NN denotes activity
T219 195-201 NN denotes kinase
T218 191-194 NN denotes Akt
T217 186-190 IN denotes that
T216 181-185 VB denotes show
T215 178-180 PRP denotes We
T214 170-176 NN denotes kinase
T213 168-169 -RRB- denotes )
T212 164-168 NN denotes RIP1
T211 163-164 -LRB- denotes (
T210 153-162 NN denotes protein-1
T209 141-152 NN denotes interacting
T208 132-140 NN denotes receptor
T207 123-131 NN denotes mediator
T206 111-122 NN denotes necroptosis
T205 107-110 DT denotes the
T204 104-106 IN denotes by
T203 93-103 VB denotes controlled
T202 82-92 NN denotes mechanisms
T201 72-81 NN denotes signaling
T200 68-71 DT denotes the
T199 55-67 VB denotes investigated
T198 52-54 PRP denotes we
T197 50-51 -COMMA- denotes ,
T196 46-50 NN denotes work
T195 41-45 DT denotes this
T194 38-40 IN denotes In
T193 35-36 -RRB- denotes )
T192 31-35 NN denotes SIRS
T191 30-31 -LRB- denotes (
T190 21-29 NN denotes syndrome
T189 12-20 NN denotes response
R52 T190 T189 arg1Of syndrome,response
R53 T190 T191 arg1Of syndrome,(
R54 T192 T191 arg2Of SIRS,(
R55 T193 T191 arg3Of ),(
R56 T196 T194 arg2Of work,In
R57 T196 T195 arg1Of work,this
R58 T198 T199 arg1Of we,investigated
R59 T199 T194 arg1Of investigated,In
R60 T199 T197 arg1Of investigated,","
R61 T202 T199 arg2Of mechanisms,investigated
R62 T202 T200 arg1Of mechanisms,the
R63 T202 T201 arg1Of mechanisms,signaling
R64 T202 T203 arg2Of mechanisms,controlled
R65 T212 T211 arg2Of RIP1,(
R66 T213 T211 arg3Of ),(
R67 T214 T203 arg1Of kinase,controlled
R68 T214 T204 arg2Of kinase,by
R69 T214 T205 arg1Of kinase,the
R70 T214 T206 arg1Of kinase,necroptosis
R71 T214 T207 arg1Of kinase,mediator
R72 T214 T208 arg1Of kinase,receptor
R73 T214 T209 arg1Of kinase,interacting
R74 T214 T210 arg1Of kinase,protein-1
R75 T214 T211 arg1Of kinase,(
R76 T215 T216 arg1Of We,show
R77 T220 T218 arg1Of activity,Akt
R78 T220 T219 arg1Of activity,kinase
R79 T220 T221 arg1Of activity,is
R80 T220 T222 arg1Of activity,critical
R81 T220 T229 arg1Of activity,plays
R82 T221 T225 arg1Of is,in
R83 T221 T228 arg1Of is,and
R84 T222 T221 arg2Of critical,is
R85 T222 T223 arg1Of critical,for
R86 T224 T223 arg2Of necroptosis,for
R87 T227 T225 arg2Of cells,in
R88 T227 T226 arg1Of cells,L929
R89 T228 T216 arg2Of and,show
R90 T228 T217 arg1Of and,that
R91 T229 T228 arg2Of plays,and
R92 T229 T233 arg1Of plays,in
R93 T232 T229 arg2Of role,plays
R94 T232 T230 arg1Of role,a
R95 T232 T231 arg1Of role,key
R96 T235 T233 arg2Of production,in
R97 T235 T234 arg1Of production,TNFα
R98 T237 T236 arg2Of necroptosis,During
R99 T239 T240 arg1Of Akt,is
R100 T239 T241 arg2Of Akt,activated
R101 T241 T236 arg1Of activated,During
R102 T241 T238 arg1Of activated,","
R103 T241 T240 arg2Of activated,is
R104 T241 T242 arg1Of activated,in
R105 T241 T247 arg1Of activated,through
R106 T245 T244 arg1Of dependent,RIP1
R107 T246 T242 arg2Of fashion,in
R108 T246 T243 arg1Of fashion,a
R109 T246 T245 arg1Of fashion,dependent
R110 T249 T247 arg2Of phosphorylation,through
R111 T249 T248 arg1Of phosphorylation,its
R112 T249 T250 arg1Of phosphorylation,on
R113 T251 T250 arg2Of Thr308,on
R114 T254 T252 arg2Of cells,In
R115 T254 T253 arg1Of cells,L929

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T90 132-162 Protein denotes receptor interacting protein-1
T91 164-168 Protein denotes RIP1
T92 277-281 Protein denotes TNFα
T93 336-340 Protein denotes RIP1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T407 336-340 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T406 164-168 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T402 277-281 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T396 314-317 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T395 191-194 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T389 314-317 http://www.uniprot.org/uniprot/P31751 denotes Akt
T388 191-194 http://www.uniprot.org/uniprot/P31751 denotes Akt
T381 191-194 http://www.uniprot.org/uniprot/P31749 denotes Akt
T382 314-317 http://www.uniprot.org/uniprot/P31749 denotes Akt

GO-BP

Id Subject Object Predicate Lexical cue
T130 371-386 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T129 195-210 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T127 72-81 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T111 301-312 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T110 227-238 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T109 111-122 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T103 301-312 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T102 227-238 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T101 111-122 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis

GO-MF

Id Subject Object Predicate Lexical cue
T135 195-210 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity

sentences

Id Subject Object Predicate Lexical cue
T62 38-177 Sentence denotes In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase.
T63 178-293 Sentence denotes We show that Akt kinase activity is critical for necroptosis in L929 cells and plays a key role in TNFα production.
T64 294-397 Sentence denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308.
T5 38-177 Sentence denotes In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase.
T6 178-293 Sentence denotes We show that Akt kinase activity is critical for necroptosis in L929 cells and plays a key role in TNFα production.
T7 294-397 Sentence denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308.

simple1

Id Subject Object Predicate Lexical cue
T145 132-162 Protein denotes receptor interacting protein-1
T146 164-168 Protein denotes RIP1
T147 277-281 Protein denotes TNFα
T148 336-340 Protein denotes RIP1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T355 132-162 Protein denotes receptor interacting protein-1
T356 164-168 Protein denotes RIP1
T357 277-281 Protein denotes TNFα
T358 336-340 Protein denotes RIP1
T366 269-273 Regulation denotes role
T367 282-292 Gene_expression denotes production
R452 T357 T367 themeOf TNFα,production
R456 T367 T366 themeOf production,role

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T443 132-162 Protein denotes receptor interacting protein-1
T444 164-168 Protein denotes RIP1
T445 277-281 Protein denotes TNFα
T446 336-340 Protein denotes RIP1
T454 282-292 Gene_expression denotes production
R471 T445 T454 themeOf TNFα,production

DLUT931

Id Subject Object Predicate Lexical cue
T424 269-273 Regulation denotes role
T412 132-162 Protein denotes receptor interacting protein-1
T413 164-168 Protein denotes RIP1
T414 277-281 Protein denotes TNFα
T415 336-340 Protein denotes RIP1
T423 282-292 Gene_expression denotes production
R459 T414 T423 themeOf TNFα,production
R463 T423 T424 themeOf production,role

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T764 277-292 Gene_expression denotes TNFα production
T758 294-396 Phosphorylation denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308
T757 294-396 Positive_regulation denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308
T748 104-176 Protein denotes by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase
T746 164-168 Protein denotes RIP1
T745 336-350 Protein denotes RIP1 dependent
T743 191-194 Protein denotes Akt
T742 191-201 Protein denotes Akt kinase
T737 387-396 Entity denotes on Thr308
T736 132-169 Protein denotes receptor interacting protein-1 (RIP1)
T734 277-281 Protein denotes TNFα
T729 314-317 Protein denotes Akt
R433 T737 T758 siteOf on Thr308,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R429 T729 T757 themeOf Akt,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R430 T729 T758 themeOf Akt,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R431 T734 T764 themeOf TNFα,TNFα production
R432 T737 T729 partOf on Thr308,Akt

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T594 413-417 DT denotes this
T533 52-54 PRP denotes we
T532 50-51 , denotes ,
T531 46-50 NN denotes work
T530 41-45 DT denotes this
T529 38-40 IN denotes In
T528 36-37 . denotes .
T527 35-36 -RRB- denotes )
T526 31-35 NNP denotes SIRS
T525 30-31 -LRB- denotes (
T524 21-29 NN denotes syndrome
T523 12-20 NN denotes response
T573 294-300 IN denotes During
T572 292-293 . denotes .
T571 282-292 NN denotes production
T570 277-281 JJ denotes TNFα
T569 274-276 IN denotes in
T568 269-273 NN denotes role
T567 265-268 JJ denotes key
T566 263-264 DT denotes a
T565 257-262 VBZ denotes plays
T564 253-256 CC denotes and
T563 247-252 NNS denotes cells
T562 242-246 CD denotes L929
T561 239-241 IN denotes in
T560 227-238 NN denotes necroptosis
T559 223-226 IN denotes for
T558 214-222 JJ denotes critical
T557 211-213 VBZ denotes is
T556 202-210 NN denotes activity
T555 195-201 NN denotes kinase
T554 191-194 NNP denotes Akt
T553 186-190 IN denotes that
T552 181-185 VBP denotes show
T551 178-180 PRP denotes We
T550 176-177 . denotes .
T549 170-176 NN denotes kinase
T548 168-169 -RRB- denotes )
T547 164-168 CD denotes RIP1
T546 163-164 -LRB- denotes (
T545 153-162 NN denotes protein-1
T544 141-152 VBG denotes interacting
T543 132-140 NN denotes receptor
T542 123-131 NN denotes mediator
T541 111-122 NN denotes necroptosis
T540 107-110 DT denotes the
T539 104-106 IN denotes by
T538 93-103 VBN denotes controlled
T537 82-92 NNS denotes mechanisms
T536 72-81 VBG denotes signaling
T535 68-71 DT denotes the
T534 55-67 VBD denotes investigated
T593 411-412 , denotes ,
T592 406-411 NNS denotes cells
T591 401-405 CD denotes L929
T590 398-400 IN denotes In
T589 396-397 . denotes .
T588 390-396 NNP denotes Thr308
T587 387-389 IN denotes on
T586 371-386 NN denotes phosphorylation
T585 367-370 PRP$ denotes its
T584 359-366 IN denotes through
T583 351-358 NN denotes fashion
T582 341-350 JJ denotes dependent
T581 336-340 NNP denotes RIP1
T580 334-335 DT denotes a
T579 331-333 IN denotes in
T578 321-330 VBN denotes activated
T577 318-320 VBZ denotes is
T576 314-317 NNP denotes Akt
T575 312-313 , denotes ,
T574 301-312 NN denotes necroptosis
R263 T523 T524 compound response,syndrome
R265 T525 T524 punct (,syndrome
R266 T526 T524 appos SIRS,syndrome
R267 T527 T524 punct ),syndrome
R269 T529 T534 prep In,investigated
R270 T530 T531 det this,work
R271 T531 T529 pobj work,In
R272 T532 T534 punct ",",investigated
R273 T533 T534 nsubj we,investigated
R274 T534 T534 ROOT investigated,investigated
R275 T535 T537 det the,mechanisms
R276 T536 T537 amod signaling,mechanisms
R277 T537 T534 dobj mechanisms,investigated
R278 T538 T537 acl controlled,mechanisms
R279 T539 T538 agent by,controlled
R280 T540 T543 det the,receptor
R281 T541 T542 amod necroptosis,mediator
R282 T542 T543 compound mediator,receptor
R283 T543 T539 pobj receptor,by
R284 T544 T543 acl interacting,receptor
R285 T545 T544 dobj protein-1,interacting
R286 T546 T545 punct (,protein-1
R287 T547 T545 appos RIP1,protein-1
R288 T548 T545 punct ),protein-1
R289 T549 T543 conj kinase,receptor
R290 T550 T534 punct .,investigated
R291 T551 T552 nsubj We,show
R292 T552 T552 ROOT show,show
R293 T553 T557 mark that,is
R294 T554 T556 compound Akt,activity
R295 T555 T556 compound kinase,activity
R296 T556 T557 nsubj activity,is
R297 T557 T552 ccomp is,show
R298 T558 T557 acomp critical,is
R299 T559 T558 prep for,critical
R300 T560 T559 pobj necroptosis,for
R301 T561 T557 prep in,is
R302 T562 T563 nummod L929,cells
R303 T563 T561 pobj cells,in
R304 T564 T557 cc and,is
R305 T565 T557 conj plays,is
R306 T566 T568 det a,role
R307 T567 T568 amod key,role
R308 T568 T565 dobj role,plays
R309 T569 T568 prep in,role
R310 T570 T571 amod TNFα,production
R311 T571 T569 pobj production,in
R312 T572 T552 punct .,show
R313 T573 T578 prep During,activated
R314 T574 T573 pobj necroptosis,During
R315 T575 T578 punct ",",activated
R316 T576 T578 nsubjpass Akt,activated
R317 T577 T578 auxpass is,activated
R318 T578 T578 ROOT activated,activated
R319 T579 T578 prep in,activated
R320 T580 T583 det a,fashion
R321 T581 T583 nmod RIP1,fashion
R322 T582 T583 amod dependent,fashion
R323 T583 T579 pobj fashion,in
R324 T584 T578 prep through,activated
R325 T585 T586 poss its,phosphorylation
R326 T586 T584 pobj phosphorylation,through
R327 T587 T586 prep on,phosphorylation
R328 T588 T587 pobj Thr308,on
R329 T589 T578 punct .,activated
R331 T591 T592 nummod L929,cells
R332 T592 T590 pobj cells,In

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T474 321-330 Positive_regulation denotes activated
T473 371-386 Phosphorylation denotes phosphorylation
T472 321-330 Positive_regulation denotes activated
T471 390-396 Protein denotes Thr308
T470 336-340 Protein denotes RIP1
T469 314-317 Protein denotes Akt
T468 282-292 Gene_expression denotes production
T467 277-281 Protein denotes TNFα
T466 191-201 Protein denotes Akt kinase
T465 93-103 Regulation denotes controlled
T464 93-103 Regulation denotes controlled
T463 164-168 Protein denotes RIP1
T462 123-162 Protein denotes mediator receptor interacting protein-1
R216 T462 T464 themeOf mediator receptor interacting protein-1,controlled
R217 T463 T465 themeOf RIP1,controlled
R218 T467 T468 themeOf TNFα,production
R219 T469 T472 themeOf Akt,activated
R220 T471 T473 themeOf Thr308,phosphorylation
R221 T473 T474 themeOf phosphorylation,activated

test3

Id Subject Object Predicate Lexical cue
T51 371-386 Phosphorylation denotes phosphorylation
T50 336-340 Protein denotes RIP1
T49 321-330 Positive_regulation denotes activated
T48 282-292 Gene_expression denotes production
T47 277-281 Protein denotes TNFα
T46 269-273 Regulation denotes role
T45 164-168 Protein denotes RIP1
T44 132-162 Protein denotes receptor interacting protein-1
T43 93-103 Regulation denotes controlled
T34 336-340 Protein denotes RIP1
T33 277-281 Protein denotes TNFα
T32 164-168 Protein denotes RIP1
T31 132-162 Protein denotes receptor interacting protein-1
R8 T44 T43 causeOf receptor interacting protein-1,controlled
R9 T45 T44 equivalentTo RIP1,receptor interacting protein-1
R10 T47 T48 themeOf TNFα,production
R11 T48 T46 themeOf production,role
R12 T50 T49 themeOf RIP1,activated