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PMC:3585731 / 30780-31556 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T13521 206-215 Positive_regulation denotes increased
T13520 142-157 Phosphorylation denotes Phosphorylation
T13519 75-84 Positive_regulation denotes increased
T13479 740-747 Protein denotes Myr-Akt
T13478 624-628 Protein denotes MDM2
T13477 614-619 Protein denotes FoxO1
T13476 510-515 Protein denotes FoxO4
T13475 496-498 Protein denotes S6
T13474 488-494 Protein denotes p70S6K
T13473 452-459 Protein denotes Myr-Akt
T13472 260-265 Protein denotes K179M
T13471 239-246 Protein denotes Myr-Akt
T13470 85-92 Protein denotes Myr-Akt
T13469 48-55 Protein denotes Myr-Akt
T13528 721-736 Phosphorylation denotes phosphorylation
T13527 647-656 Positive_regulation denotes increased
T13526 595-610 Phosphorylation denotes phosphorylation
T13525 528-542 Phosphorylation denotes phosphorylated
T13524 424-433 Positive_regulation denotes increased
T13523 225-235 Gene_expression denotes expression
T13522 216-220 Positive_regulation denotes upon
R8898 T13471 T13523 themeOf Myr-Akt,expression
R8899 T13474 T13525 themeOf p70S6K,phosphorylated
R8900 T13475 T13525 themeOf S6,phosphorylated
R8901 T13476 T13525 themeOf FoxO4,phosphorylated
R8902 T13477 T13526 themeOf FoxO1,phosphorylation
R8903 T13478 T13526 themeOf MDM2,phosphorylation
R8904 T13479 T13528 themeOf Myr-Akt,phosphorylation
R8919 T13523 T13521 causeOf expression,increased
R8920 T13523 T13522 themeOf expression,upon
R8921 T13526 T13527 themeOf phosphorylation,increased

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T14483 767-775 NN denotes activity
T14482 763-766 PRP-DOLLAR- denotes its
T14481 754-762 VB denotes promoted
T14480 748-753 RB denotes still
T14479 740-747 NN denotes Myr-Akt
T14478 737-739 IN denotes of
T14477 721-736 NN denotes phosphorylation
T14476 714-720 NN denotes Thr308
T14475 702-713 JJ denotes necroptotic
T14474 697-701 IN denotes that
T14473 686-696 VB denotes indicating
T14472 684-685 -COMMA- denotes ,
T14471 676-684 NN denotes zVAD.fmk
T14470 673-675 IN denotes of
T14469 664-672 NN denotes presence
T14468 660-663 DT denotes the
T14467 657-659 IN denotes in
T14466 647-656 VB denotes increased
T14465 633-646 RB denotes significantly
T14464 629-632 VB denotes was
T14463 624-628 NN denotes MDM2
T14462 620-623 CC denotes and
T14461 614-619 NN denotes FoxO1
T14460 611-613 IN denotes of
T14459 595-610 NN denotes phosphorylation
T14458 593-594 -COMMA- denotes ,
T14457 589-593 NN denotes hand
T14456 583-588 JJ denotes other
T14455 579-582 DT denotes the
T14454 576-578 IN denotes On
T14453 566-574 NN denotes zVAD.fmk
T14452 563-565 IN denotes of
T14451 555-562 NN denotes absence
T14450 551-554 DT denotes the
T14449 548-550 IN denotes in
T14448 543-547 RB denotes even
T14447 528-542 VB denotes phosphorylated
T14446 522-527 RB denotes fully
T14445 517-521 VB denotes were
T14444 515-516 -COMMA- denotes ,
T14443 510-515 NN denotes FoxO4
T14442 506-509 CC denotes and
T14441 500-505 NN denotes GSK-3
T14440 498-499 -COMMA- denotes ,
T14439 496-498 NN denotes S6
T14438 494-495 -COMMA- denotes ,
T14437 488-494 NN denotes p70S6K
T14436 478-487 VB denotes including
T14435 476-477 -COMMA- denotes ,
T14434 466-476 NN denotes substrates
T14433 461-465 DT denotes Some
T14432 452-460 NNP denotes Myr-Akt.
T14431 449-451 IN denotes of
T14430 440-448 NN denotes activity
T14429 434-439 JJ denotes basal
T14428 424-433 VB denotes increased
T14427 420-423 DT denotes the
T14426 417-419 TO denotes to
T14425 413-416 IN denotes due
T14424 406-412 RB denotes likely
T14423 404-405 -COMMA- denotes ,
T14422 398-404 VB denotes varied
T14421 382-397 NN denotes phosphorylation
T14420 376-381 PRP-DOLLAR- denotes their
T14419 373-375 IN denotes on
T14418 364-372 NN denotes zVAD.fmk
T14417 361-363 IN denotes of
T14416 354-360 NN denotes effect
T14415 350-353 DT denotes The
T14414 347-348 -RRB- denotes )
T14413 345-347 NN denotes 7C
T14412 340-344 NN denotes Fig.
T14411 339-340 -LRB- denotes (
T14410 333-338 NN denotes cells
T14409 328-332 NN denotes L929
T14408 325-327 IN denotes in
T14407 314-324 NN denotes substrates
T14406 310-313 NNP denotes Akt
T14405 306-309 VB denotes are
T14404 296-305 NN denotes molecules
T14403 290-295 DT denotes these
T14402 285-289 IN denotes that
T14401 274-284 VB denotes confirming
T14400 272-273 -COMMA- denotes ,
T14399 266-272 NN denotes mutant
T14398 260-265 NN denotes K179M
T14397 256-259 DT denotes the
T14396 252-255 RB denotes not
T14395 248-251 CC denotes but
T14394 246-247 -COMMA- denotes ,
T14393 239-246 NN denotes Myr-Akt
T14392 236-238 IN denotes of
T14391 225-235 NN denotes expression
T14390 221-224 DT denotes the
T14389 216-220 IN denotes upon
T14388 206-215 VB denotes increased
T14387 202-205 VB denotes was
T14370 102-104 IN denotes as
T14369 93-101 NN denotes activity
T14368 85-92 NN denotes Myr-Akt
T14367 75-84 VB denotes increased
T14366 63-74 NN denotes necroptosis
T14365 56-62 IN denotes during
T14364 48-55 NN denotes Myr-Akt
T14363 45-47 IN denotes of
T14386 191-201 NN denotes substrates
T14385 187-190 NN denotes Akt
T14384 177-186 VB denotes described
T14383 166-176 RB denotes previously
T14382 161-165 JJ denotes many
T14381 158-160 IN denotes of
T14380 142-157 NN denotes Phosphorylation
T14379 139-140 -RRB- denotes )
T14378 138-139 CD denotes 5
T14377 133-137 NNP denotes Fig.
T14376 132-133 -LRB- denotes (
T14375 128-131 NN denotes Akt
T14374 117-127 JJ denotes endogenous
T14373 112-116 IN denotes with
T14372 108-111 VB denotes did
T14371 105-107 PRP denotes it
R9349 T14364 T14363 arg2Of Myr-Akt,of
R9350 T14366 T14365 arg2Of necroptosis,during
R9351 T14369 T14367 arg2Of activity,increased
R9352 T14369 T14368 arg1Of activity,Myr-Akt
R9353 T14370 T14367 arg3Of as,increased
R9354 T14371 T14372 arg1Of it,did
R9355 T14372 T14370 arg2Of did,as
R9356 T14372 T14373 arg1Of did,with
R9357 T14372 T14376 arg1Of did,(
R9358 T14375 T14373 arg2Of Akt,with
R9359 T14375 T14374 arg1Of Akt,endogenous
R9360 T14377 T14376 arg2Of Fig.,(
R9361 T14377 T14378 arg1Of Fig.,5
R9362 T14379 T14376 arg3Of ),(
R9363 T14380 T14381 arg1Of Phosphorylation,of
R9364 T14380 T14387 arg1Of Phosphorylation,was
R9365 T14380 T14388 arg2Of Phosphorylation,increased
R9366 T14384 T14383 arg1Of described,previously
R9367 T14386 T14381 arg2Of substrates,of
R9368 T14386 T14382 arg1Of substrates,many
R9369 T14386 T14384 arg1Of substrates,described
R9370 T14386 T14385 arg1Of substrates,Akt
R9371 T14388 T14387 arg2Of increased,was
R9372 T14388 T14389 arg1Of increased,upon
R9373 T14388 T14400 arg1Of increased,","
R9374 T14388 T14401 modOf increased,confirming
R9375 T14391 T14390 arg1Of expression,the
R9376 T14391 T14392 arg1Of expression,of
R9377 T14391 T14395 arg1Of expression,but
R9378 T14393 T14392 arg2Of Myr-Akt,of
R9379 T14395 T14389 arg2Of but,upon
R9380 T14395 T14394 arg1Of but,","
R9381 T14395 T14396 arg1Of but,not
R9382 T14399 T14395 arg2Of mutant,but
R9383 T14399 T14397 arg1Of mutant,the
R9384 T14399 T14398 arg1Of mutant,K179M
R9385 T14404 T14403 arg1Of molecules,these
R9386 T14404 T14405 arg1Of molecules,are
R9387 T14405 T14401 arg2Of are,confirming
R9388 T14405 T14402 arg1Of are,that
R9389 T14405 T14408 arg1Of are,in
R9390 T14407 T14405 arg2Of substrates,are
R9391 T14407 T14406 arg1Of substrates,Akt
R9392 T14410 T14408 arg2Of cells,in
R9393 T14410 T14409 arg1Of cells,L929
R9394 T14410 T14411 arg1Of cells,(
R9395 T14413 T14411 arg2Of 7C,(
R9396 T14413 T14412 arg1Of 7C,Fig.
R9397 T14414 T14411 arg3Of ),(
R9398 T14416 T14415 arg1Of effect,The
R9399 T14416 T14417 arg1Of effect,of
R9400 T14416 T14419 arg1Of effect,on
R9401 T14416 T14422 arg1Of effect,varied
R9402 T14418 T14417 arg2Of zVAD.fmk,of
R9403 T14421 T14419 arg2Of phosphorylation,on
R9404 T14421 T14420 arg1Of phosphorylation,their
R9405 T14422 T14423 arg1Of varied,","
R9406 T14422 T14424 arg1Of varied,likely
R9407 T14422 T14425 arg1Of varied,due
R9408 T14425 T14426 arg1Of due,to
R9409 T14430 T14425 arg2Of activity,due
R9410 T14430 T14427 arg1Of activity,the
R9411 T14430 T14428 arg2Of activity,increased
R9412 T14430 T14429 arg1Of activity,basal
R9413 T14430 T14431 arg1Of activity,of
R9414 T14432 T14431 arg2Of Myr-Akt.,of
R9415 T14434 T14433 arg1Of substrates,Some
R9416 T14434 T14435 arg1Of substrates,","
R9417 T14434 T14436 arg1Of substrates,including
R9418 T14434 T14445 arg1Of substrates,were
R9419 T14434 T14447 arg2Of substrates,phosphorylated
R9420 T14437 T14438 arg1Of p70S6K,","
R9421 T14438 T14440 arg1Of ",",","
R9422 T14439 T14438 arg2Of S6,","
R9423 T14440 T14442 arg1Of ",",and
R9424 T14441 T14440 arg2Of GSK-3,","
R9425 T14442 T14436 arg2Of and,including
R9426 T14443 T14442 arg2Of FoxO4,and
R9427 T14447 T14422 arg2Of phosphorylated,varied
R9428 T14447 T14444 arg1Of phosphorylated,","
R9429 T14447 T14445 arg2Of phosphorylated,were
R9430 T14447 T14446 arg1Of phosphorylated,fully
R9431 T14447 T14449 arg1Of phosphorylated,in
R9432 T14449 T14448 arg1Of in,even
R9433 T14451 T14449 arg2Of absence,in
R9434 T14451 T14450 arg1Of absence,the
R9435 T14451 T14452 arg1Of absence,of
R9436 T14453 T14452 arg2Of zVAD.fmk,of
R9437 T14457 T14454 arg2Of hand,On
R9438 T14457 T14455 arg1Of hand,the
R9439 T14457 T14456 arg1Of hand,other
R9440 T14459 T14460 arg1Of phosphorylation,of
R9441 T14459 T14464 arg1Of phosphorylation,was
R9442 T14459 T14466 arg2Of phosphorylation,increased
R9443 T14461 T14462 arg1Of FoxO1,and
R9444 T14462 T14460 arg2Of and,of
R9445 T14463 T14462 arg2Of MDM2,and
R9446 T14466 T14454 arg1Of increased,On
R9447 T14466 T14458 arg1Of increased,","
R9448 T14466 T14464 arg2Of increased,was
R9449 T14466 T14465 arg1Of increased,significantly
R9450 T14466 T14467 arg1Of increased,in
R9451 T14466 T14472 arg1Of increased,","
R9452 T14466 T14473 modOf increased,indicating
R9453 T14467 T14468 arg1Of in,the
R9454 T14467 T14470 arg1Of in,of
R9455 T14469 T14467 arg2Of presence,in
R9456 T14471 T14467 arg3Of zVAD.fmk,in
R9457 T14477 T14475 arg1Of phosphorylation,necroptotic
R9458 T14477 T14476 arg1Of phosphorylation,Thr308
R9459 T14477 T14478 arg1Of phosphorylation,of
R9460 T14477 T14481 arg1Of phosphorylation,promoted
R9461 T14479 T14478 arg2Of Myr-Akt,of
R9462 T14481 T14473 arg2Of promoted,indicating
R9463 T14481 T14474 arg1Of promoted,that
R9464 T14481 T14480 arg1Of promoted,still
R9465 T14483 T14481 arg2Of activity,promoted
R9466 T14483 T14482 arg1Of activity,its

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T13860 740-747 Protein denotes Myr-Akt
T13859 624-628 Protein denotes MDM2
T13858 614-619 Protein denotes FoxO1
T13857 510-515 Protein denotes FoxO4
T13856 496-498 Protein denotes S6
T13855 488-494 Protein denotes p70S6K
T13854 452-459 Protein denotes Myr-Akt
T13853 260-265 Protein denotes K179M
T13852 239-246 Protein denotes Myr-Akt
T13851 85-92 Protein denotes Myr-Akt
T13850 48-55 Protein denotes Myr-Akt

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T15075 310-313 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15074 243-246 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15073 187-190 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15072 128-131 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15071 89-92 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15070 52-55 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15042 744-747 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15041 456-459 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15040 310-313 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15039 243-246 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15038 187-190 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15037 128-131 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15036 89-92 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15035 52-55 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15007 744-747 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15006 456-459 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15005 310-313 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15004 243-246 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15003 187-190 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15002 128-131 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15001 89-92 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15000 52-55 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15099 614-619 http://www.uniprot.org/uniprot/Q12778 denotes FoxO1
T15077 744-747 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15076 456-459 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt

GO-BP

Id Subject Object Predicate Lexical cue
T13944 500-503 http://purl.obolibrary.org/obo/GO_0050321 denotes GSK
T13931 721-736 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T13930 595-610 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T13929 382-397 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T13900 63-74 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T13886 63-74 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis

GO-MF

Id Subject Object Predicate Lexical cue
T13960 500-503 http://purl.obolibrary.org/obo/GO_0050321 denotes GSK

GO-CC

Id Subject Object Predicate Lexical cue
T13967 333-338 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T13709 576-776 Sentence denotes On the other hand, phosphorylation of FoxO1 and MDM2 was significantly increased in the presence of zVAD.fmk, indicating that necroptotic Thr308 phosphorylation of Myr-Akt still promoted its activity.
T13708 350-575 Sentence denotes The effect of zVAD.fmk on their phosphorylation varied, likely due to the increased basal activity of Myr-Akt. Some substrates, including p70S6K, S6, GSK-3 and FoxO4, were fully phosphorylated even in the absence of zVAD.fmk.
T13707 142-349 Sentence denotes Phosphorylation of many previously described Akt substrates was increased upon the expression of Myr-Akt, but not the K179M mutant, confirming that these molecules are Akt substrates in L929 cells (Fig. 7C).
T193 0-141 Sentence denotes RIP1 kinase-dependent Thr308 phosphorylation of Myr-Akt during necroptosis increased Myr-Akt activity as it did with endogenous Akt (Fig. 5).
T194 142-349 Sentence denotes Phosphorylation of many previously described Akt substrates was increased upon the expression of Myr-Akt, but not the K179M mutant, confirming that these molecules are Akt substrates in L929 cells (Fig. 7C).
T195 350-460 Sentence denotes The effect of zVAD.fmk on their phosphorylation varied, likely due to the increased basal activity of Myr-Akt.
T196 461-575 Sentence denotes Some substrates, including p70S6K, S6, GSK-3 and FoxO4, were fully phosphorylated even in the absence of zVAD.fmk.
T197 576-776 Sentence denotes On the other hand, phosphorylation of FoxO1 and MDM2 was significantly increased in the presence of zVAD.fmk, indicating that necroptotic Thr308 phosphorylation of Myr-Akt still promoted its activity.

simple1

Id Subject Object Predicate Lexical cue
T14041 614-619 Protein denotes FoxO1
T14040 510-515 Protein denotes FoxO4
T14039 496-498 Protein denotes S6
T14038 488-494 Protein denotes p70S6K
T14037 452-459 Protein denotes Myr-Akt
T14036 260-265 Protein denotes K179M
T14035 239-246 Protein denotes Myr-Akt
T14034 85-92 Protein denotes Myr-Akt
T14033 48-55 Protein denotes Myr-Akt
T14043 740-747 Protein denotes Myr-Akt
T14042 624-628 Protein denotes MDM2

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T14970 721-736 Phosphorylation denotes phosphorylation
T14969 595-610 Phosphorylation denotes phosphorylation
T14968 647-656 Positive_regulation denotes increased
T14967 528-542 Phosphorylation denotes phosphorylated
T14966 424-433 Positive_regulation denotes increased
T14965 206-215 Positive_regulation denotes increased
T14964 225-235 Gene_expression denotes expression
T14961 75-84 Positive_regulation denotes increased
T14939 740-747 Protein denotes Myr-Akt
T14938 624-628 Protein denotes MDM2
T14937 614-619 Protein denotes FoxO1
T14936 510-515 Protein denotes FoxO4
T14935 496-498 Protein denotes S6
T14934 488-494 Protein denotes p70S6K
T14933 452-459 Protein denotes Myr-Akt
T14932 260-265 Protein denotes K179M
T14931 239-246 Protein denotes Myr-Akt
T14930 85-92 Protein denotes Myr-Akt
T14929 48-55 Protein denotes Myr-Akt
R9919 T14930 T14961 themeOf Myr-Akt,increased
R9920 T14931 T14964 themeOf Myr-Akt,expression
R9921 T14932 T14964 themeOf K179M,expression
R9922 T14933 T14966 themeOf Myr-Akt,increased
R9923 T14934 T14967 themeOf p70S6K,phosphorylated
R9924 T14935 T14967 themeOf S6,phosphorylated
R9925 T14936 T14967 themeOf FoxO4,phosphorylated
R9926 T14937 T14969 themeOf FoxO1,phosphorylation
R9927 T14938 T14969 themeOf MDM2,phosphorylation
R9928 T14939 T14970 themeOf Myr-Akt,phosphorylation
R9943 T14964 T14965 themeOf expression,increased
R9944 T14964 T14965 themeOf expression,increased
R9945 T14969 T14968 themeOf phosphorylation,increased
R9946 T14969 T14968 themeOf phosphorylation,increased

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T15283 647-656 Positive_regulation denotes increased
T15282 595-610 Phosphorylation denotes phosphorylation
T15281 721-736 Phosphorylation denotes phosphorylation
T15280 528-542 Phosphorylation denotes phosphorylated
T15279 225-235 Gene_expression denotes expression
T15278 206-215 Positive_regulation denotes increased
T15276 75-84 Positive_regulation denotes increased
T15246 260-265 Protein denotes K179M
T15245 239-246 Protein denotes Myr-Akt
T15244 85-92 Protein denotes Myr-Akt
T15243 48-55 Protein denotes Myr-Akt
T15253 740-747 Protein denotes Myr-Akt
T15252 624-628 Protein denotes MDM2
T15251 614-619 Protein denotes FoxO1
T15250 510-515 Protein denotes FoxO4
T15249 496-498 Protein denotes S6
T15248 488-494 Protein denotes p70S6K
T15247 452-459 Protein denotes Myr-Akt
R10017 T15245 T15279 themeOf Myr-Akt,expression
R10018 T15248 T15280 themeOf p70S6K,phosphorylated
R10019 T15249 T15280 themeOf S6,phosphorylated
R10020 T15250 T15280 themeOf FoxO4,phosphorylated
R10021 T15251 T15282 themeOf FoxO1,phosphorylation
R10022 T15252 T15282 themeOf MDM2,phosphorylation
R10023 T15253 T15281 themeOf Myr-Akt,phosphorylation
R10037 T15279 T15278 themeOf expression,increased
R10038 T15282 T15283 themeOf phosphorylation,increased
R10039 T15282 T15283 themeOf phosphorylation,increased

DLUT931

Id Subject Object Predicate Lexical cue
T15157 721-736 Phosphorylation denotes phosphorylation
T15156 647-656 Positive_regulation denotes increased
T15155 595-610 Phosphorylation denotes phosphorylation
T15154 528-542 Phosphorylation denotes phosphorylated
T15153 424-433 Positive_regulation denotes increased
T15152 206-215 Positive_regulation denotes increased
T15151 225-235 Gene_expression denotes expression
T15126 740-747 Protein denotes Myr-Akt
T15125 624-628 Protein denotes MDM2
T15124 614-619 Protein denotes FoxO1
T15123 510-515 Protein denotes FoxO4
T15122 496-498 Protein denotes S6
T15121 488-494 Protein denotes p70S6K
T15120 452-459 Protein denotes Myr-Akt
T15119 260-265 Protein denotes K179M
T15118 239-246 Protein denotes Myr-Akt
T15117 85-92 Protein denotes Myr-Akt
T15116 48-55 Protein denotes Myr-Akt
R9957 T15118 T15151 themeOf Myr-Akt,expression
R9958 T15119 T15151 themeOf K179M,expression
R9959 T15120 T15153 themeOf Myr-Akt,increased
R9960 T15121 T15154 themeOf p70S6K,phosphorylated
R9961 T15122 T15154 themeOf S6,phosphorylated
R9962 T15123 T15154 themeOf FoxO4,phosphorylated
R9963 T15124 T15155 themeOf FoxO1,phosphorylation
R9964 T15125 T15155 themeOf MDM2,phosphorylation
R9965 T15126 T15157 themeOf Myr-Akt,phosphorylation
R9987 T15151 T15152 themeOf expression,increased
R9988 T15151 T15152 themeOf expression,increased
R9989 T15155 T15156 themeOf phosphorylation,increased
R9990 T15155 T15156 themeOf phosphorylation,increased

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T15771 702-747 Phosphorylation denotes necroptotic Thr308 phosphorylation of Myr-Akt
T15764 221-273 Gene_expression denotes the expression of Myr-Akt, but not the K179M mutant,
T15761 420-459 Positive_regulation denotes the increased basal activity of Myr-Akt
T15755 595-685 Positive_regulation denotes phosphorylation of FoxO1 and MDM2 was significantly increased in the presence of zVAD.fmk,
T15754 595-685 Positive_regulation denotes phosphorylation of FoxO1 and MDM2 was significantly increased in the presence of zVAD.fmk,
T15751 595-628 Phosphorylation denotes phosphorylation of FoxO1 and MDM2
T15750 595-628 Phosphorylation denotes phosphorylation of FoxO1 and MDM2
T15741 496-498 Protein denotes S6
T15698 510-515 Protein denotes FoxO4
T15685 128-131 Protein denotes Akt
T15684 187-201 Entity denotes Akt substrates
T15677 187-190 Protein denotes Akt
T15675 461-516 Entity denotes Some substrates, including p70S6K, S6, GSK-3 and FoxO4,
T15666 563-574 Entity denotes of zVAD.fmk
T15663 500-505 Protein denotes GSK-3
T15656 614-619 Protein denotes FoxO1
T15644 256-272 Protein denotes the K179M mutant
T15638 673-684 Entity denotes of zVAD.fmk
T15632 290-305 Entity denotes these molecules
T15631 737-747 Protein denotes of Myr-Akt
T15630 310-324 Entity denotes Akt substrates
T15614 449-459 Protein denotes of Myr-Akt
T15612 85-92 Protein denotes Myr-Akt
T15610 236-246 Protein denotes of Myr-Akt
T15609 310-313 Protein denotes Akt
T15718 624-628 Protein denotes MDM2
T15714 488-494 Protein denotes p70S6K
T15708 45-55 Protein denotes of Myr-Akt
T15707 361-372 Entity denotes of zVAD.fmk
T15706 714-720 Entity denotes Thr308
R10211 T15610 T15764 themeOf of Myr-Akt,"the expression of Myr-Akt, but not the K179M mutant,"
R10213 T15614 T15761 themeOf of Myr-Akt,the increased basal activity of Myr-Akt
R10223 T15656 T15751 themeOf FoxO1,phosphorylation of FoxO1 and MDM2
R10234 T15706 T15631 partOf Thr308,of Myr-Akt
R10237 T15718 T15750 themeOf MDM2,phosphorylation of FoxO1 and MDM2
R10239 T15750 T15754 themeOf phosphorylation of FoxO1 and MDM2,"phosphorylation of FoxO1 and MDM2 was significantly increased in the presence of zVAD.fmk,"
R10240 T15751 T15755 themeOf phosphorylation of FoxO1 and MDM2,"phosphorylation of FoxO1 and MDM2 was significantly increased in the presence of zVAD.fmk,"
R10235 T15706 T15771 siteOf Thr308,necroptotic Thr308 phosphorylation of Myr-Akt
R10216 T15631 T15771 themeOf of Myr-Akt,necroptotic Thr308 phosphorylation of Myr-Akt

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T16208 775-776 . denotes .
T16207 767-775 NN denotes activity
T16206 763-766 PRP$ denotes its
T16205 754-762 VBD denotes promoted
T16204 748-753 RB denotes still
T16203 740-747 NNP denotes Myr-Akt
T16202 737-739 IN denotes of
T16201 721-736 NN denotes phosphorylation
T16200 714-720 NNP denotes Thr308
T16199 702-713 JJ denotes necroptotic
T16198 697-701 IN denotes that
T16197 686-696 VBG denotes indicating
T16196 684-685 , denotes ,
T16195 676-684 NNP denotes zVAD.fmk
T16194 673-675 IN denotes of
T16193 664-672 NN denotes presence
T16192 660-663 DT denotes the
T16191 657-659 IN denotes in
T16190 647-656 VBN denotes increased
T16189 633-646 RB denotes significantly
T16188 629-632 VBD denotes was
T16187 624-628 NNP denotes MDM2
T16186 620-623 CC denotes and
T16185 614-619 NNP denotes FoxO1
T16184 611-613 IN denotes of
T16183 595-610 NN denotes phosphorylation
T16182 593-594 , denotes ,
T16181 589-593 NN denotes hand
T16180 583-588 JJ denotes other
T16179 579-582 DT denotes the
T16178 576-578 IN denotes On
T16177 574-575 . denotes .
T16176 566-574 NNP denotes zVAD.fmk
T16175 563-565 IN denotes of
T16174 555-562 NN denotes absence
T16173 551-554 DT denotes the
T16172 548-550 IN denotes in
T16171 543-547 RB denotes even
T16170 528-542 VBN denotes phosphorylated
T16169 522-527 RB denotes fully
T16168 517-521 VBD denotes were
T16167 515-516 , denotes ,
T16166 510-515 NNP denotes FoxO4
T16165 506-509 CC denotes and
T16164 500-505 NNP denotes GSK-3
T16163 498-499 , denotes ,
T16162 496-498 NNP denotes S6
T16161 494-495 , denotes ,
T16160 488-494 NNP denotes p70S6K
T16159 478-487 VBG denotes including
T16158 476-477 , denotes ,
T16157 466-476 NNS denotes substrates
T16156 461-465 DT denotes Some
T16155 459-460 . denotes .
T16154 452-459 NNP denotes Myr-Akt
T16153 449-451 IN denotes of
T16152 440-448 NN denotes activity
T16151 434-439 NN denotes basal
T16150 424-433 VBN denotes increased
T16149 420-423 DT denotes the
T16148 417-419 TO denotes to
T16147 413-416 JJ denotes due
T16146 406-412 JJ denotes likely
T16145 404-405 , denotes ,
T16144 398-404 VBD denotes varied
T16143 382-397 NN denotes phosphorylation
T16142 376-381 PRP$ denotes their
T16141 373-375 IN denotes on
T16140 364-372 NNP denotes zVAD.fmk
T16139 361-363 IN denotes of
T16138 354-360 NN denotes effect
T16137 350-353 DT denotes The
T16136 348-349 . denotes .
T16135 347-348 -RRB- denotes )
T16134 345-347 NNP denotes 7C
T16133 340-344 NNP denotes Fig.
T16132 339-340 -LRB- denotes (
T16131 333-338 NNS denotes cells
T16130 328-332 CD denotes L929
T16129 325-327 IN denotes in
T16128 314-324 VBZ denotes substrates
T16127 310-313 NNP denotes Akt
T16126 306-309 VBP denotes are
T16125 296-305 NNS denotes molecules
T16124 290-295 DT denotes these
T16104 166-176 RB denotes previously
T16103 161-165 JJ denotes many
T16102 158-160 IN denotes of
T16101 142-157 NNP denotes Phosphorylation
T16100 140-141 . denotes .
T16099 139-140 -RRB- denotes )
T16098 138-139 CD denotes 5
T16097 133-137 NNP denotes Fig.
T16096 132-133 -LRB- denotes (
T16095 128-131 NNP denotes Akt
T16094 117-127 JJ denotes endogenous
T16093 112-116 IN denotes with
T16092 108-111 VBD denotes did
T16091 105-107 PRP denotes it
T16090 102-104 IN denotes as
T16089 93-101 NN denotes activity
T16088 85-92 NNP denotes Myr-Akt
T16087 75-84 VBD denotes increased
T16086 63-74 NN denotes necroptosis
T16085 56-62 IN denotes during
T16084 48-55 NNP denotes Myr-Akt
T16083 45-47 IN denotes of
T16123 285-289 IN denotes that
T16122 274-284 VBG denotes confirming
T16121 272-273 , denotes ,
T16120 266-272 JJ denotes mutant
T16119 260-265 NNP denotes K179M
T16118 256-259 DT denotes the
T16117 252-255 RB denotes not
T16116 248-251 CC denotes but
T16115 246-247 , denotes ,
T16114 239-246 NNP denotes Myr-Akt
T16113 236-238 IN denotes of
T16112 225-235 NN denotes expression
T16111 221-224 DT denotes the
T16110 216-220 IN denotes upon
T16109 206-215 VBN denotes increased
T16108 202-205 VBD denotes was
T16107 191-201 NNS denotes substrates
T16106 187-190 NNP denotes Akt
T16105 177-186 VBN denotes described
R10556 T16084 T16083 pobj Myr-Akt,of
R10557 T16085 T16087 prep during,increased
R10558 T16086 T16085 pobj necroptosis,during
R10559 T16087 T16087 ROOT increased,increased
R10560 T16088 T16089 compound Myr-Akt,activity
R10561 T16089 T16087 dobj activity,increased
R10562 T16090 T16092 mark as,did
R10563 T16091 T16092 nsubj it,did
R10564 T16092 T16087 advcl did,increased
R10565 T16093 T16092 prep with,did
R10566 T16094 T16095 compound endogenous,Akt
R10567 T16095 T16093 pobj Akt,with
R10568 T16096 T16097 punct (,Fig.
R10569 T16097 T16095 appos Fig.,Akt
R10570 T16098 T16097 nummod 5,Fig.
R10571 T16099 T16095 punct ),Akt
R10572 T16100 T16087 punct .,increased
R10573 T16101 T16109 nsubjpass Phosphorylation,increased
R10574 T16102 T16101 prep of,Phosphorylation
R10575 T16103 T16107 amod many,substrates
R10576 T16104 T16105 advmod previously,described
R10577 T16105 T16107 amod described,substrates
R10578 T16106 T16107 compound Akt,substrates
R10579 T16107 T16102 pobj substrates,of
R10580 T16108 T16109 auxpass was,increased
R10581 T16109 T16109 ROOT increased,increased
R10582 T16110 T16109 prep upon,increased
R10583 T16111 T16112 det the,expression
R10584 T16112 T16110 pobj expression,upon
R10585 T16113 T16112 prep of,expression
R10586 T16114 T16113 pobj Myr-Akt,of
R10587 T16115 T16109 punct ",",increased
R10588 T16116 T16109 cc but,increased
R10589 T16117 T16120 neg not,mutant
R10590 T16118 T16120 det the,mutant
R10591 T16119 T16120 compound K179M,mutant
R10592 T16120 T16128 amod mutant,substrates
R10593 T16121 T16120 punct ",",mutant
R10594 T16122 T16120 acl confirming,mutant
R10595 T16123 T16126 mark that,are
R10596 T16124 T16125 det these,molecules
R10597 T16125 T16126 nsubj molecules,are
R10598 T16126 T16122 ccomp are,confirming
R10599 T16127 T16128 compound Akt,substrates
R10600 T16128 T16109 conj substrates,increased
R10601 T16129 T16128 prep in,substrates
R10602 T16130 T16131 nummod L929,cells
R10603 T16131 T16129 pobj cells,in
R10604 T16132 T16128 punct (,substrates
R10605 T16133 T16134 compound Fig.,7C
R10606 T16134 T16128 appos 7C,substrates
R10607 T16135 T16128 punct ),substrates
R10608 T16136 T16109 punct .,increased
R10609 T16137 T16138 det The,effect
R10610 T16138 T16144 nsubj effect,varied
R10611 T16139 T16138 prep of,effect
R10612 T16140 T16139 pobj zVAD.fmk,of
R10613 T16141 T16138 prep on,effect
R10614 T16142 T16143 poss their,phosphorylation
R10615 T16143 T16141 pobj phosphorylation,on
R10616 T16144 T16144 ROOT varied,varied
R10617 T16145 T16144 punct ",",varied
R10618 T16146 T16147 amod likely,due
R10619 T16147 T16148 amod due,to
R10620 T16148 T16144 prep to,varied
R10621 T16149 T16152 det the,activity
R10622 T16150 T16152 amod increased,activity
R10623 T16151 T16152 compound basal,activity
R10624 T16152 T16148 pobj activity,to
R10625 T16153 T16152 prep of,activity
R10626 T16154 T16153 pobj Myr-Akt,of
R10627 T16155 T16144 punct .,varied
R10628 T16156 T16157 det Some,substrates
R10629 T16157 T16170 nsubjpass substrates,phosphorylated
R10630 T16158 T16157 punct ",",substrates
R10631 T16159 T16157 prep including,substrates
R10632 T16160 T16159 pobj p70S6K,including
R10633 T16161 T16160 punct ",",p70S6K
R10634 T16162 T16160 conj S6,p70S6K
R10635 T16163 T16162 punct ",",S6
R10636 T16164 T16162 conj GSK-3,S6
R10637 T16165 T16164 cc and,GSK-3
R10638 T16166 T16164 conj FoxO4,GSK-3
R10639 T16167 T16170 punct ",",phosphorylated
R10640 T16168 T16170 auxpass were,phosphorylated
R10641 T16169 T16170 advmod fully,phosphorylated
R10642 T16170 T16170 ROOT phosphorylated,phosphorylated
R10643 T16171 T16172 advmod even,in
R10644 T16172 T16170 prep in,phosphorylated
R10645 T16173 T16174 det the,absence
R10646 T16174 T16172 pobj absence,in
R10647 T16175 T16174 prep of,absence
R10648 T16176 T16175 pobj zVAD.fmk,of
R10649 T16177 T16170 punct .,phosphorylated
R10650 T16178 T16190 prep On,increased
R10651 T16179 T16181 det the,hand
R10652 T16180 T16181 amod other,hand
R10653 T16181 T16178 pobj hand,On
R10654 T16182 T16190 punct ",",increased
R10655 T16183 T16190 nsubjpass phosphorylation,increased
R10656 T16184 T16183 prep of,phosphorylation
R10657 T16185 T16184 pobj FoxO1,of
R10658 T16186 T16185 cc and,FoxO1
R10659 T16187 T16185 conj MDM2,FoxO1
R10660 T16188 T16190 auxpass was,increased
R10661 T16189 T16190 advmod significantly,increased
R10662 T16190 T16190 ROOT increased,increased
R10663 T16191 T16190 prep in,increased
R10664 T16192 T16193 det the,presence
R10666 T16193 T16191 pobj presence,in
R10668 T16194 T16193 prep of,presence
R10671 T16195 T16194 pobj zVAD.fmk,of
R10674 T16196 T16190 punct ",",increased
R10676 T16197 T16190 advcl indicating,increased
R10677 T16198 T16205 mark that,promoted
R10681 T16199 T16201 amod necroptotic,phosphorylation
R10685 T16200 T16201 compound Thr308,phosphorylation
R10689 T16201 T16205 nsubj phosphorylation,promoted
R10692 T16202 T16201 prep of,phosphorylation
R10695 T16203 T16202 pobj Myr-Akt,of
R10699 T16204 T16205 advmod still,promoted
R10703 T16205 T16197 ccomp promoted,indicating
R10707 T16206 T16207 poss its,activity
R10714 T16207 T16205 dobj activity,promoted
R10718 T16208 T16190 punct .,increased

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T15378 647-656 Positive_regulation denotes increased
T15377 595-610 Phosphorylation denotes phosphorylation
T15376 595-610 Phosphorylation denotes phosphorylation
T15375 744-747 Protein denotes Akt
T15374 740-743 Protein denotes Myr
T15373 624-628 Protein denotes MDM2
T15372 614-619 Protein denotes FoxO1
T15371 528-542 Phosphorylation denotes phosphorylated
T15370 528-542 Phosphorylation denotes phosphorylated
T15369 528-542 Phosphorylation denotes phosphorylated
T15368 528-542 Phosphorylation denotes phosphorylated
T15367 510-515 Protein denotes FoxO4
T15366 500-505 Protein denotes GSK-3
T15365 496-498 Protein denotes S6
T15364 488-494 Protein denotes p70S6K
T15363 424-433 Positive_regulation denotes increased
T15362 452-459 Protein denotes Myr-Akt
T15361 225-235 Gene_expression denotes expression
T15360 225-235 Gene_expression denotes expression
T15359 206-215 Positive_regulation denotes increased
T15358 142-157 Phosphorylation denotes Phosphorylation
T15357 310-313 Protein denotes Akt
T15356 243-246 Protein denotes Akt
T15355 239-242 Protein denotes Myr
T15347 89-92 Protein denotes Akt
T15346 85-88 Protein denotes Myr
T15345 48-55 Protein denotes Myr-Akt
T15354 187-190 Protein denotes Akt
T15352 75-84 Positive_regulation denotes increased
T15351 75-84 Positive_regulation denotes increased
T15349 133-136 Protein denotes Fig
T15348 128-131 Protein denotes Akt
T15382 721-736 Phosphorylation denotes phosphorylation
T15381 721-736 Phosphorylation denotes phosphorylation
T15380 702-713 Entity denotes necroptotic
T15379 647-656 Positive_regulation denotes increased
R10070 T15347 T15351 themeOf Akt,increased
R10071 T15347 T15352 themeOf Akt,increased
R10072 T15349 T15351 causeOf Fig,increased
R10075 T15354 T15358 themeOf Akt,Phosphorylation
R10076 T15355 T15360 themeOf Myr,expression
R10077 T15356 T15361 themeOf Akt,expression
R10078 T15358 T15359 themeOf Phosphorylation,increased
R10079 T15362 T15363 themeOf Myr-Akt,increased
R10080 T15364 T15368 themeOf p70S6K,phosphorylated
R10081 T15365 T15369 themeOf S6,phosphorylated
R10082 T15366 T15370 themeOf GSK-3,phosphorylated
R10083 T15367 T15371 themeOf FoxO4,phosphorylated
R10084 T15372 T15376 themeOf FoxO1,phosphorylation
R10085 T15373 T15377 themeOf MDM2,phosphorylation
R10086 T15374 T15381 themeOf Myr,phosphorylation
R10087 T15374 T15380 partOf Myr,necroptotic
R10088 T15375 T15382 themeOf Akt,phosphorylation
R10089 T15375 T15380 partOf Akt,necroptotic
R10090 T15376 T15378 themeOf phosphorylation,increased
R10091 T15377 T15379 themeOf phosphorylation,increased
R10092 T15380 T15381 Site necroptotic,phosphorylation
R10093 T15380 T15382 Site necroptotic,phosphorylation

test3

Id Subject Object Predicate Lexical cue
T13646 740-747 Protein denotes Myr-Akt
T13645 721-736 Phosphorylation denotes phosphorylation
T13644 647-656 Positive_regulation denotes increased
T13643 624-628 Protein denotes MDM2
T13642 614-619 Protein denotes FoxO1
T13641 595-610 Phosphorylation denotes phosphorylation
T13640 555-562 Negative_regulation denotes absence
T13639 528-542 Phosphorylation denotes phosphorylated
T13638 510-515 Protein denotes FoxO4
T13637 496-498 Protein denotes S6
T13636 488-494 Protein denotes p70S6K
T13635 452-459 Protein denotes Myr-Akt
T13634 424-433 Positive_regulation denotes increased
T13633 260-265 Protein denotes K179M
T13632 239-246 Protein denotes Myr-Akt
T13631 225-235 Gene_expression denotes expression
T13630 206-215 Positive_regulation denotes increased
T13629 85-92 Protein denotes Myr-Akt
T13628 75-84 Positive_regulation denotes increased
T13627 48-55 Protein denotes Myr-Akt
T13577 740-747 Protein denotes Myr-Akt
T13576 624-628 Protein denotes MDM2
T13575 614-619 Protein denotes FoxO1
T13574 510-515 Protein denotes FoxO4
T13573 496-498 Protein denotes S6
T13572 488-494 Protein denotes p70S6K
T13571 452-459 Protein denotes Myr-Akt
T13570 260-265 Protein denotes K179M
T13569 239-246 Protein denotes Myr-Akt
T13568 85-92 Protein denotes Myr-Akt
T13567 48-55 Protein denotes Myr-Akt
R8938 T13629 T13628 themeOf Myr-Akt,increased
R8939 T13632 T13631 themeOf Myr-Akt,expression
R8940 T13633 T13631 themeOf K179M,expression
R8941 T13636 T13639 themeOf p70S6K,phosphorylated
R8942 T13637 T13639 themeOf S6,phosphorylated
R8943 T13638 T13639 themeOf FoxO4,phosphorylated
R8944 T13641 T13644 themeOf phosphorylation,increased
R8945 T13642 T13641 themeOf FoxO1,phosphorylation
R8946 T13643 T13641 themeOf MDM2,phosphorylation
R8947 T13646 T13645 themeOf Myr-Akt,phosphorylation