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PMC:3585731 / 27827-29580 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T13516 1726-1733 Regulation denotes changes
T13515 1709-1717 Positive_regulation denotes required
T13514 1600-1610 Positive_regulation denotes activation
T13513 1587-1595 Regulation denotes regulate
T13512 1497-1507 Positive_regulation denotes activation
T13511 1484-1492 Negative_regulation denotes uncouple
T13510 1470-1480 Positive_regulation denotes sufficient
T13509 1239-1251 Positive_regulation denotes upregulation
T13508 1209-1224 Phosphorylation denotes phosphorylation
T13507 1181-1191 Positive_regulation denotes activation
T13506 1088-1103 Phosphorylation denotes phosphorylation
T13505 1065-1073 Positive_regulation denotes increase
T13504 945-952 Positive_regulation denotes induced
T13503 589-599 Gene_expression denotes expressing
T13502 480-486 Entity denotes domain
T13501 445-453 Negative_regulation denotes deletion
T13500 398-410 Localization denotes localization
T13499 216-226 Positive_regulation denotes activation
T13498 26-36 Gene_expression denotes expressing
T13467 1666-1670 Protein denotes RIP1
T13466 1557-1561 Protein denotes RIP1
T13465 1255-1259 Protein denotes TNFα
T13464 1203-1208 Protein denotes c-Jun
T13463 999-1006 Protein denotes Myr-Akt
T13462 907-912 Protein denotes K179M
T13461 886-893 Protein denotes Myr-Akt
T13460 600-607 Protein denotes Myr-Akt
T13459 275-282 Protein denotes Myr-Akt
T13458 269-273 Protein denotes Akt1
T13457 197-201 Protein denotes RIP1
T13456 121-126 Protein denotes K179M
T13455 75-82 Protein denotes Myr-Akt
T13454 69-73 Protein denotes Akt1
R8889 T13454 T13498 themeOf Akt1,expressing
R8890 T13455 T13454 equivalentTo Myr-Akt,Akt1
R8891 T13458 T13500 themeOf Akt1,localization
R8892 T13459 T13458 equivalentTo Myr-Akt,Akt1
R8893 T13460 T13503 themeOf Myr-Akt,expressing
R8894 T13464 T13508 themeOf c-Jun,phosphorylation
R8895 T13465 T13509 themeOf TNFα,upregulation
R8896 T13466 T13513 causeOf RIP1,regulate
R8913 T13506 T13505 themeOf phosphorylation,increase
R8914 T13508 T13507 themeOf phosphorylation,activation
R8915 T13511 T13510 themeOf uncouple,sufficient
R8916 T13512 T13511 themeOf activation,uncouple
R8917 T13514 T13513 themeOf activation,regulate
R8918 T13516 T13515 themeOf changes,required

2_test

Id Subject Object Predicate Lexical cue
23469174-8702995-90505449 323-325 8702995 denotes 37

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T14358 1741-1752 NN denotes necroptosis
T14357 1734-1740 IN denotes during
T14356 1726-1733 NN denotes changes
T14355 1722-1725 NN denotes Akt
T14354 1718-1721 IN denotes for
T14353 1709-1717 VB denotes required
T14352 1702-1708 NN denotes inputs
T14351 1690-1701 JJ denotes independent
T14350 1686-1689 CD denotes two
T14349 1678-1685 VB denotes provide
T14348 1671-1677 NN denotes kinase
T14347 1666-1670 NN denotes RIP1
T14346 1662-1665 CC denotes and
T14345 1654-1661 NN denotes factors
T14344 1647-1653 NN denotes growth
T14343 1642-1646 IN denotes that
T14342 1631-1641 VB denotes suggesting
T14341 1629-1630 -COMMA- denotes ,
T14340 1618-1629 NN denotes necroptosis
T14339 1611-1617 IN denotes during
T14338 1600-1610 NN denotes activation
T14337 1596-1599 NN denotes Akt
T14336 1587-1595 VB denotes regulate
T14335 1584-1586 TO denotes to
T14334 1579-1583 JJ denotes able
T14333 1573-1578 RB denotes still
T14332 1569-1572 VB denotes was
T14331 1562-1568 NN denotes kinase
T14330 1557-1561 NN denotes RIP1
T14329 1546-1555 NN denotes signaling
T14328 1539-1545 NN denotes factor
T14327 1532-1538 NN denotes growth
T14326 1527-1531 IN denotes from
T14325 1515-1526 NN denotes necroptosis
T14324 1508-1514 IN denotes during
T14323 1497-1507 NN denotes activation
T14322 1493-1496 NN denotes Akt
T14321 1484-1492 VB denotes uncouple
T14320 1481-1483 TO denotes to
T14319 1470-1480 JJ denotes sufficient
T14318 1467-1469 VB denotes is
T14317 1463-1466 NN denotes Akt
T14316 1453-1462 VB denotes localized
T14315 1444-1452 NN denotes membrane
T14314 1440-1443 CC denotes and
T14313 1433-1439 JJ denotes active
T14312 1430-1432 IN denotes of
T14311 1421-1429 NN denotes presence
T14310 1417-1420 DT denotes the
T14309 1412-1416 IN denotes that
T14308 1399-1411 VB denotes demonstrated
T14307 1394-1398 NN denotes data
T14306 1388-1393 DT denotes These
T14305 1377-1386 NN denotes signaling
T14304 1365-1376 JJ denotes necroptotic
T14303 1362-1364 IN denotes of
T14302 1357-1361 NN denotes apex
T14301 1353-1356 DT denotes the
T14300 1350-1352 IN denotes at
T14299 1346-1349 NN denotes Akt
T14298 1342-1345 IN denotes for
T14297 1337-1341 NN denotes role
T14296 1327-1336 JJ denotes important
T14295 1324-1326 DT denotes an
T14294 1313-1323 VB denotes confirming
T14293 1311-1312 -COMMA- denotes ,
T14292 1301-1311 NN denotes conditions
T14291 1296-1300 JJ denotes free
T14290 1290-1295 NN denotes serum
T14289 1284-1289 IN denotes under
T14288 1278-1283 VB denotes occur
T14287 1275-1277 TO denotes to
T14286 1273-1274 -RRB- denotes )
T14285 1271-1273 NN denotes 7D
T14284 1266-1270 NNP denotes Fig.
T14283 1265-1266 -LRB- denotes (
T14282 1260-1264 NN denotes mRNA
T14281 1255-1259 NN denotes TNFα
T14280 1252-1254 IN denotes of
T14279 1239-1251 NN denotes upregulation
T14278 1235-1238 CC denotes and
T14277 1233-1234 -RRB- denotes )
T14276 1231-1233 NN denotes 7C
T14275 1226-1230 NN denotes Fig.
T14274 1225-1226 -LRB- denotes (
T14273 1209-1224 NN denotes phosphorylation
T14272 1203-1208 NN denotes c-Jun
T14271 1199-1202 CC denotes and
T14270 1195-1198 NN denotes JNK
T14269 1192-1194 IN denotes of
T14268 1181-1191 NN denotes activation
T14267 1171-1180 VB denotes including
T14266 1169-1170 -COMMA- denotes ,
T14265 1163-1169 NN denotes events
T14264 1144-1162 JJ denotes zVAD.fmk-dependent
T14263 1138-1143 JJ denotes other
T14262 1130-1137 VB denotes allowed
T14261 1125-1129 RB denotes also
T14260 1117-1124 NN denotes Myr-Akt
T14259 1114-1115 -RRB- denotes )
T14258 1113-1114 NN denotes C
T14257 1112-1113 -COMMA- denotes ,
T14256 1110-1112 NN denotes 7B
T14255 1105-1109 NNP denotes Fig.
T14254 1104-1105 -LRB- denotes (
T14253 1088-1103 NN denotes phosphorylation
T14252 1081-1087 NN denotes Thr308
T14251 1077-1080 NN denotes Akt
T14250 1074-1076 IN denotes in
T14249 1065-1073 NN denotes increase
T14248 1057-1064 VB denotes delayed
T14247 1036-1056 JJ denotes necroptosis-specific
T14246 1032-1035 DT denotes the
T14245 1028-1031 CC denotes and
T14244 1022-1027 NN denotes death
T14243 1017-1021 NN denotes cell
T14242 1007-1016 JJ denotes dependent
T14241 999-1006 NN denotes Myr-Akt
T14240 994-998 CC denotes both
T14239 984-993 VB denotes prevented
T14238 978-983 NN denotes Nec-1
T14237 975-976 -RRB- denotes )
T14236 974-975 NN denotes B
T14235 973-974 -COMMA- denotes ,
T14234 971-973 NNP denotes 7A
T14233 966-970 NNP denotes Fig.
T14232 965-966 -LRB- denotes (
T14231 953-964 NN denotes necroptosis
T14230 936-952 JJ denotes zVAD.fmk-induced
T14229 927-935 VB denotes restored
T14228 921-926 RB denotes fully
T14227 919-920 -COMMA- denotes ,
T14226 913-919 NN denotes mutant
T14225 907-912 NN denotes K179M
T14224 903-906 DT denotes the
T14223 899-902 RB denotes not
T14222 895-898 CC denotes but
T14221 893-894 -COMMA- denotes ,
T14220 886-893 NN denotes Myr-Akt
T14219 875-885 NN denotes conditions
T14218 870-874 JJ denotes free
T14217 864-869 NN denotes serum
T14216 858-863 IN denotes Under
T14215 851-856 NN denotes death
T14214 846-850 NN denotes cell
T14213 834-845 JJ denotes necroptotic
T14212 827-833 VB denotes induce
T14211 824-826 TO denotes to
T14210 813-823 JJ denotes sufficient
T14209 809-812 RB denotes not
T14208 806-808 VB denotes is
T14207 800-805 RB denotes alone
T14206 796-799 NN denotes Akt
T14205 789-795 JJ denotes active
T14204 784-788 IN denotes that
T14203 774-783 VB denotes indicates
T14202 769-773 DT denotes This
T14201 766-767 -RRB- denotes )
T14200 764-766 NN denotes 7B
T14199 759-763 NNP denotes Fig.
T14198 758-759 -LRB- denotes (
T14197 747-757 NN denotes starvation
T14196 741-746 NN denotes serum
T14195 738-740 IN denotes by
T14194 726-737 NN denotes necroptosis
T14193 719-725 VB denotes induce
T14192 716-718 TO denotes to
T14191 706-715 VB denotes triggered
T14190 702-705 RB denotes not
T14189 697-701 VB denotes were
T14188 693-696 CC denotes and
T14187 691-692 -COMMA- denotes ,
T14186 686-691 NN denotes cells
T14185 678-685 NN denotes control
T14184 671-677 NN denotes vector
T14183 665-670 JJ denotes empty
T14182 661-664 DT denotes the
T14181 656-660 IN denotes from
T14180 638-655 JJ denotes indistinguishable
T14179 631-637 NN denotes manner
T14178 629-630 DT denotes a
T14177 626-628 IN denotes in
T14176 621-625 VB denotes grew
T14175 619-620 -COMMA- denotes ,
T14174 613-619 JJ denotes viable
T14173 608-612 VB denotes were
T14172 600-607 NN denotes Myr-Akt
T14171 589-599 VB denotes expressing
T14170 583-588 NN denotes cells
T14169 579-582 DT denotes the
T14168 574-578 IN denotes that
T14167 569-573 VB denotes note
T14166 566-568 TO denotes to
T14165 556-565 JJ denotes important
T14164 553-555 VB denotes is
T14163 550-552 PRP denotes It
T14162 544-548 JJ denotes free
T14161 538-543 NN denotes serum
T14160 532-537 IN denotes under
T14159 525-531 JJ denotes active
T14158 522-524 VB denotes is
T14157 517-521 WDT denotes that
T14156 513-516 NN denotes Akt
T14155 510-512 DT denotes an
T14154 507-509 IN denotes in
T14153 497-506 VB denotes resulting
T14152 495-496 -RRB- denotes )
T14151 493-495 NN denotes 7A
T14150 488-492 NN denotes Fig.
T14149 487-488 -LRB- denotes (
T14148 480-486 NN denotes domain
T14147 477-479 NN denotes PH
T14146 461-476 JJ denotes auto-inhibitory
T14145 457-460 DT denotes the
T14144 454-456 IN denotes of
T14143 445-453 NN denotes deletion
T14142 441-444 DT denotes the
T14141 438-440 IN denotes by
T14140 434-437 CC denotes and
T14139 425-433 NN denotes membrane
T14138 418-424 NN denotes plasma
T14137 414-417 DT denotes the
T14136 411-413 TO denotes to
T14135 398-410 NN denotes localization
T14134 385-397 JJ denotes constitutive
T14133 376-384 VB denotes provides
T14132 370-375 WDT denotes which
T14131 363-369 NN denotes signal
T14130 348-362 NN denotes myristoylation
T14129 346-347 DT denotes a
T14128 343-345 IN denotes of
T14127 334-342 NN denotes addition
T14126 330-333 DT denotes the
T14125 327-329 IN denotes by
T14124 325-326 -RRB- denotes ]
T14123 323-325 CD denotes 37
T14122 322-323 -LRB- denotes [
T14121 312-321 VB denotes described
T14120 301-311 RB denotes previously
T14119 298-300 IN denotes as
T14118 288-297 VB denotes generated
T14117 284-287 VB denotes was
T14116 282-283 -RRB- denotes )
T14115 275-282 NN denotes Myr-Akt
T14114 274-275 -LRB- denotes (
T14113 269-273 NN denotes Akt1
T14112 262-268 JJ denotes active
T14111 247-261 RB denotes Constitutively
T14110 234-245 NN denotes necroptosis
T14109 227-233 IN denotes during
T14108 216-226 NN denotes activation
T14107 212-215 NN denotes Akt
T14106 209-211 TO denotes to
T14105 202-208 NN denotes kinase
T14104 197-201 NN denotes RIP1
T14103 193-196 CC denotes and
T14102 185-192 NN denotes factors
T14101 178-184 NN denotes growth
T14100 175-177 IN denotes of
T14099 162-174 NN denotes contribution
T14098 158-161 DT denotes the
T14097 147-157 VB denotes understand
T14096 139-146 RB denotes further
T14095 136-138 TO denotes to
T14094 130-135 NN denotes order
T14093 127-129 IN denotes in
T14092 121-126 NN denotes K179M
T14091 114-120 JJ denotes mutant
T14090 105-113 JJ denotes inactive
T14089 91-104 RB denotes catalytically
T14088 87-90 DT denotes the
T14087 84-86 CC denotes or
T14086 82-83 -RRB- denotes )
T14085 75-82 NN denotes Myr-Akt
T14084 74-75 -LRB- denotes (
T14083 69-73 NN denotes Akt1
T14082 64-68 NN denotes type
T14081 59-63 JJ denotes wild
T14080 52-58 JJ denotes active
T14079 37-51 RB denotes constitutively
T14078 26-36 VB denotes expressing
T14077 19-25 RB denotes stably
T14076 13-18 NN denotes cells
T14075 8-12 NN denotes L929
T14074 3-7 VB denotes used
T14073 0-2 PRP denotes We
R9053 T14073 T14074 arg1Of We,used
R9054 T14076 T14074 arg2Of cells,used
R9055 T14076 T14075 arg1Of cells,L929
R9056 T14076 T14078 arg1Of cells,expressing
R9057 T14076 T14097 arg1Of cells,understand
R9058 T14078 T14077 arg1Of expressing,stably
R9059 T14078 T14093 arg1Of expressing,in
R9060 T14080 T14079 arg1Of active,constitutively
R9061 T14083 T14080 arg1Of Akt1,active
R9062 T14083 T14081 arg1Of Akt1,wild
R9063 T14083 T14082 arg1Of Akt1,type
R9064 T14083 T14084 arg1Of Akt1,(
R9065 T14083 T14087 arg1Of Akt1,or
R9066 T14085 T14084 arg2Of Myr-Akt,(
R9067 T14086 T14084 arg3Of ),(
R9068 T14087 T14078 arg2Of or,expressing
R9069 T14092 T14087 arg2Of K179M,or
R9070 T14092 T14088 arg1Of K179M,the
R9071 T14092 T14089 arg1Of K179M,catalytically
R9072 T14092 T14090 arg1Of K179M,inactive
R9073 T14092 T14091 arg1Of K179M,mutant
R9074 T14094 T14093 arg2Of order,in
R9075 T14097 T14093 arg3Of understand,in
R9076 T14097 T14095 arg1Of understand,to
R9077 T14097 T14096 arg1Of understand,further
R9078 T14099 T14097 arg2Of contribution,understand
R9079 T14099 T14098 arg1Of contribution,the
R9080 T14099 T14100 arg1Of contribution,of
R9081 T14099 T14106 arg1Of contribution,to
R9082 T14102 T14101 arg1Of factors,growth
R9083 T14102 T14103 arg1Of factors,and
R9084 T14103 T14100 arg2Of and,of
R9085 T14105 T14103 arg2Of kinase,and
R9086 T14105 T14104 arg1Of kinase,RIP1
R9087 T14108 T14106 arg2Of activation,to
R9088 T14108 T14107 arg1Of activation,Akt
R9089 T14108 T14109 arg1Of activation,during
R9090 T14110 T14109 arg2Of necroptosis,during
R9091 T14112 T14111 arg1Of active,Constitutively
R9092 T14113 T14112 arg1Of Akt1,active
R9093 T14113 T14114 arg1Of Akt1,(
R9094 T14113 T14117 arg1Of Akt1,was
R9095 T14113 T14118 arg2Of Akt1,generated
R9096 T14115 T14114 arg2Of Myr-Akt,(
R9097 T14116 T14114 arg3Of ),(
R9098 T14118 T14117 arg2Of generated,was
R9099 T14118 T14119 arg1Of generated,as
R9100 T14118 T14125 arg1Of generated,by
R9101 T14118 T14141 arg1Of generated,by
R9102 T14121 T14120 arg1Of described,previously
R9103 T14123 T14119 arg2Of 37,as
R9104 T14123 T14121 arg1Of 37,described
R9105 T14123 T14122 arg2Of 37,[
R9106 T14124 T14122 arg3Of ],[
R9107 T14125 T14140 arg1Of by,and
R9108 T14127 T14125 arg2Of addition,by
R9109 T14127 T14126 arg1Of addition,the
R9110 T14127 T14128 arg1Of addition,of
R9111 T14131 T14128 arg2Of signal,of
R9112 T14131 T14129 arg1Of signal,a
R9113 T14131 T14130 arg1Of signal,myristoylation
R9114 T14131 T14132 arg1Of signal,which
R9115 T14131 T14133 arg1Of signal,provides
R9116 T14135 T14133 arg2Of localization,provides
R9117 T14135 T14134 arg1Of localization,constitutive
R9118 T14135 T14136 arg1Of localization,to
R9119 T14139 T14136 arg2Of membrane,to
R9120 T14139 T14137 arg1Of membrane,the
R9121 T14139 T14138 arg1Of membrane,plasma
R9122 T14141 T14140 arg2Of by,and
R9123 T14143 T14141 arg2Of deletion,by
R9124 T14143 T14142 arg1Of deletion,the
R9125 T14143 T14144 arg1Of deletion,of
R9126 T14148 T14144 arg2Of domain,of
R9127 T14148 T14145 arg1Of domain,the
R9128 T14148 T14146 arg1Of domain,auto-inhibitory
R9129 T14148 T14147 arg1Of domain,PH
R9130 T14148 T14149 arg1Of domain,(
R9131 T14148 T14153 arg1Of domain,resulting
R9132 T14151 T14149 arg2Of 7A,(
R9133 T14151 T14150 arg1Of 7A,Fig.
R9134 T14152 T14149 arg3Of ),(
R9135 T14153 T14154 arg1Of resulting,in
R9136 T14156 T14154 arg2Of Akt,in
R9137 T14156 T14155 arg1Of Akt,an
R9138 T14156 T14157 arg1Of Akt,that
R9139 T14156 T14158 arg1Of Akt,is
R9140 T14156 T14159 arg1Of Akt,active
R9141 T14159 T14158 arg2Of active,is
R9142 T14159 T14160 arg1Of active,under
R9143 T14161 T14160 arg2Of serum,under
R9144 T14161 T14162 arg1Of serum,free
R9145 T14165 T14164 arg2Of important,is
R9146 T14167 T14166 arg1Of note,to
R9147 T14167 T14176 arg1Of note,grew
R9148 T14167 T14189 arg1Of note,were
R9149 T14167 T14191 arg2Of note,triggered
R9150 T14170 T14169 arg1Of cells,the
R9151 T14170 T14171 arg1Of cells,expressing
R9152 T14170 T14173 arg1Of cells,were
R9153 T14170 T14174 arg1Of cells,viable
R9154 T14172 T14171 arg2Of Myr-Akt,expressing
R9155 T14173 T14167 arg2Of were,note
R9156 T14173 T14168 arg1Of were,that
R9157 T14174 T14173 arg2Of viable,were
R9158 T14176 T14177 arg1Of grew,in
R9159 T14176 T14188 arg1Of grew,and
R9160 T14179 T14177 arg2Of manner,in
R9161 T14179 T14178 arg1Of manner,a
R9162 T14179 T14180 arg1Of manner,indistinguishable
R9163 T14180 T14181 arg1Of indistinguishable,from
R9164 T14186 T14181 arg2Of cells,from
R9165 T14186 T14182 arg1Of cells,the
R9166 T14186 T14183 arg1Of cells,empty
R9167 T14186 T14184 arg1Of cells,vector
R9168 T14186 T14185 arg1Of cells,control
R9169 T14188 T14163 arg1Of and,It
R9170 T14188 T14164 arg1Of and,is
R9171 T14188 T14165 arg1Of and,important
R9172 T14188 T14175 arg1Of and,","
R9173 T14188 T14187 arg1Of and,","
R9174 T14191 T14188 arg2Of triggered,and
R9175 T14191 T14189 arg2Of triggered,were
R9176 T14191 T14190 arg1Of triggered,not
R9177 T14191 T14192 modOf triggered,to
R9178 T14193 T14192 arg1Of induce,to
R9179 T14193 T14195 arg1Of induce,by
R9180 T14194 T14193 arg2Of necroptosis,induce
R9181 T14197 T14195 arg2Of starvation,by
R9182 T14197 T14196 arg1Of starvation,serum
R9183 T14197 T14198 arg1Of starvation,(
R9184 T14200 T14198 arg2Of 7B,(
R9185 T14200 T14199 arg1Of 7B,Fig.
R9186 T14201 T14198 arg3Of ),(
R9187 T14202 T14203 arg1Of This,indicates
R9188 T14206 T14205 arg1Of Akt,active
R9189 T14206 T14207 arg1Of Akt,alone
R9190 T14206 T14208 arg1Of Akt,is
R9191 T14206 T14210 arg1Of Akt,sufficient
R9192 T14208 T14203 arg2Of is,indicates
R9193 T14208 T14204 arg1Of is,that
R9194 T14208 T14209 arg1Of is,not
R9195 T14210 T14208 arg2Of sufficient,is
R9196 T14212 T14210 arg2Of induce,sufficient
R9197 T14212 T14211 arg1Of induce,to
R9198 T14215 T14212 arg2Of death,induce
R9199 T14215 T14213 arg1Of death,necroptotic
R9200 T14215 T14214 arg1Of death,cell
R9201 T14219 T14216 arg2Of conditions,Under
R9202 T14219 T14217 arg1Of conditions,serum
R9203 T14219 T14218 arg1Of conditions,free
R9204 T14220 T14222 arg1Of Myr-Akt,but
R9205 T14222 T14221 arg1Of but,","
R9206 T14222 T14223 arg1Of but,not
R9207 T14222 T14229 arg1Of but,restored
R9208 T14226 T14222 arg2Of mutant,but
R9209 T14226 T14224 arg1Of mutant,the
R9210 T14226 T14225 arg1Of mutant,K179M
R9211 T14229 T14216 arg1Of restored,Under
R9212 T14229 T14227 arg1Of restored,","
R9213 T14229 T14228 arg1Of restored,fully
R9214 T14231 T14229 arg2Of necroptosis,restored
R9215 T14231 T14230 arg1Of necroptosis,zVAD.fmk-induced
R9216 T14231 T14232 arg1Of necroptosis,(
R9217 T14234 T14232 arg2Of 7A,(
R9218 T14234 T14233 arg1Of 7A,Fig.
R9219 T14234 T14235 arg1Of 7A,","
R9220 T14236 T14235 arg2Of B,","
R9221 T14237 T14232 arg3Of ),(
R9222 T14238 T14239 arg1Of Nec-1,prevented
R9223 T14239 T14254 arg1Of prevented,(
R9224 T14242 T14241 arg1Of dependent,Myr-Akt
R9225 T14244 T14240 arg1Of death,both
R9226 T14244 T14242 arg1Of death,dependent
R9227 T14244 T14243 arg1Of death,cell
R9228 T14244 T14245 arg1Of death,and
R9229 T14245 T14239 arg2Of and,prevented
R9230 T14249 T14245 arg2Of increase,and
R9231 T14249 T14246 arg1Of increase,the
R9232 T14249 T14247 arg1Of increase,necroptosis-specific
R9233 T14249 T14248 arg2Of increase,delayed
R9234 T14249 T14250 arg1Of increase,in
R9235 T14253 T14250 arg2Of phosphorylation,in
R9236 T14253 T14251 arg1Of phosphorylation,Akt
R9237 T14253 T14252 arg1Of phosphorylation,Thr308
R9238 T14256 T14254 arg2Of 7B,(
R9239 T14256 T14255 arg1Of 7B,Fig.
R9240 T14256 T14257 arg1Of 7B,","
R9241 T14258 T14257 arg2Of C,","
R9242 T14259 T14254 arg3Of ),(
R9243 T14260 T14262 arg1Of Myr-Akt,allowed
R9244 T14262 T14261 arg1Of allowed,also
R9245 T14262 T14293 arg1Of allowed,","
R9246 T14262 T14294 modOf allowed,confirming
R9247 T14265 T14262 arg2Of events,allowed
R9248 T14265 T14263 arg1Of events,other
R9249 T14265 T14264 arg1Of events,zVAD.fmk-dependent
R9250 T14265 T14266 arg1Of events,","
R9251 T14265 T14267 arg1Of events,including
R9252 T14265 T14288 arg1Of events,occur
R9253 T14268 T14269 arg1Of activation,of
R9254 T14268 T14271 arg1Of activation,and
R9255 T14270 T14269 arg2Of JNK,of
R9256 T14271 T14278 arg1Of and,and
R9257 T14273 T14271 arg2Of phosphorylation,and
R9258 T14273 T14272 arg1Of phosphorylation,c-Jun
R9259 T14273 T14274 arg1Of phosphorylation,(
R9260 T14276 T14274 arg2Of 7C,(
R9261 T14276 T14275 arg1Of 7C,Fig.
R9262 T14277 T14274 arg3Of ),(
R9263 T14278 T14267 arg2Of and,including
R9264 T14279 T14278 arg2Of upregulation,and
R9265 T14279 T14280 arg1Of upregulation,of
R9266 T14282 T14280 arg2Of mRNA,of
R9267 T14282 T14281 arg1Of mRNA,TNFα
R9268 T14282 T14283 arg1Of mRNA,(
R9269 T14285 T14283 arg2Of 7D,(
R9270 T14285 T14284 arg1Of 7D,Fig.
R9271 T14286 T14283 arg3Of ),(
R9272 T14288 T14262 arg3Of occur,allowed
R9273 T14288 T14287 arg1Of occur,to
R9274 T14288 T14289 arg1Of occur,under
R9275 T14292 T14289 arg2Of conditions,under
R9276 T14292 T14290 arg1Of conditions,serum
R9277 T14292 T14291 arg1Of conditions,free
R9278 T14297 T14294 arg2Of role,confirming
R9279 T14297 T14295 arg1Of role,an
R9280 T14297 T14296 arg1Of role,important
R9281 T14297 T14298 arg1Of role,for
R9282 T14297 T14300 arg1Of role,at
R9283 T14299 T14298 arg2Of Akt,for
R9284 T14302 T14300 arg2Of apex,at
R9285 T14302 T14301 arg1Of apex,the
R9286 T14302 T14303 arg1Of apex,of
R9287 T14305 T14303 arg2Of signaling,of
R9288 T14305 T14304 arg1Of signaling,necroptotic
R9289 T14307 T14306 arg1Of data,These
R9290 T14307 T14308 arg1Of data,demonstrated
R9291 T14311 T14310 arg1Of presence,the
R9292 T14311 T14312 arg1Of presence,of
R9293 T14311 T14318 arg1Of presence,is
R9294 T14311 T14319 arg1Of presence,sufficient
R9295 T14317 T14312 arg2Of Akt,of
R9296 T14317 T14313 arg1Of Akt,active
R9297 T14317 T14314 arg1Of Akt,and
R9298 T14317 T14315 arg1Of Akt,membrane
R9299 T14317 T14316 arg2Of Akt,localized
R9300 T14318 T14308 arg2Of is,demonstrated
R9301 T14318 T14309 arg1Of is,that
R9302 T14319 T14318 arg2Of sufficient,is
R9303 T14321 T14319 arg2Of uncouple,sufficient
R9304 T14321 T14320 arg1Of uncouple,to
R9305 T14321 T14324 arg1Of uncouple,during
R9306 T14323 T14321 arg2Of activation,uncouple
R9307 T14323 T14322 arg1Of activation,Akt
R9308 T14325 T14324 arg2Of necroptosis,during
R9309 T14325 T14326 arg1Of necroptosis,from
R9310 T14329 T14326 arg2Of signaling,from
R9311 T14329 T14327 arg1Of signaling,growth
R9312 T14329 T14328 arg1Of signaling,factor
R9313 T14331 T14330 arg1Of kinase,RIP1
R9314 T14331 T14332 arg1Of kinase,was
R9315 T14331 T14334 arg1Of kinase,able
R9316 T14331 T14336 arg1Of kinase,regulate
R9317 T14332 T14333 arg1Of was,still
R9318 T14332 T14341 arg1Of was,","
R9319 T14332 T14342 modOf was,suggesting
R9320 T14334 T14332 arg2Of able,was
R9321 T14336 T14334 arg2Of regulate,able
R9322 T14336 T14335 arg1Of regulate,to
R9323 T14336 T14339 arg1Of regulate,during
R9324 T14338 T14336 arg2Of activation,regulate
R9325 T14338 T14337 arg1Of activation,Akt
R9326 T14340 T14339 arg2Of necroptosis,during
R9327 T14345 T14344 arg1Of factors,growth
R9328 T14345 T14346 arg1Of factors,and
R9329 T14346 T14349 arg1Of and,provide
R9330 T14348 T14346 arg2Of kinase,and
R9331 T14348 T14347 arg1Of kinase,RIP1
R9332 T14349 T14342 arg2Of provide,suggesting
R9333 T14349 T14343 arg1Of provide,that
R9334 T14352 T14349 arg2Of inputs,provide
R9335 T14352 T14350 arg1Of inputs,two
R9336 T14352 T14351 arg1Of inputs,independent
R9337 T14352 T14353 arg2Of inputs,required
R9338 T14353 T14354 arg1Of required,for
R9339 T14356 T14354 arg2Of changes,for
R9340 T14356 T14355 arg1Of changes,Akt
R9341 T14356 T14357 arg1Of changes,during
R9342 T14358 T14357 arg2Of necroptosis,during

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T13848 1666-1670 Protein denotes RIP1
T13847 1557-1561 Protein denotes RIP1
T13846 1255-1259 Protein denotes TNFα
T13845 1203-1208 Protein denotes c-Jun
T13844 999-1006 Protein denotes Myr-Akt
T13843 907-912 Protein denotes K179M
T13842 886-893 Protein denotes Myr-Akt
T13841 600-607 Protein denotes Myr-Akt
T13840 275-282 Protein denotes Myr-Akt
T13839 269-273 Protein denotes Akt1
T13838 197-201 Protein denotes RIP1
T13837 121-126 Protein denotes K179M
T13836 75-82 Protein denotes Myr-Akt
T13835 69-73 Protein denotes Akt1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T15069 1722-1725 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15068 1596-1599 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15067 1493-1496 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15066 1463-1466 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15065 1346-1349 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15064 1121-1124 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15063 1077-1080 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15062 1003-1006 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15061 890-893 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15060 796-799 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15055 79-82 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15034 1722-1725 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15033 1596-1599 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15032 1493-1496 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15031 1463-1466 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15030 1346-1349 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15029 1121-1124 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15028 1077-1080 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15027 1003-1006 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15026 890-893 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15025 796-799 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15024 604-607 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15023 513-516 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15022 279-282 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15021 212-215 http://www.uniprot.org/uniprot/P31751 denotes Akt
T15020 79-82 http://www.uniprot.org/uniprot/P31751 denotes Akt
T14999 1722-1725 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14998 1596-1599 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14997 1493-1496 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14996 1463-1466 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14995 1346-1349 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14994 1121-1124 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14993 1077-1080 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14992 1003-1006 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14991 890-893 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14990 796-799 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14989 604-607 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14988 513-516 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14987 279-282 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15095 1255-1259 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T15093 1203-1208 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T15091 1666-1670 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T15090 1557-1561 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T15089 197-201 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T14986 212-215 http://www.uniprot.org/uniprot/P31749 denotes Akt
T14985 79-82 http://www.uniprot.org/uniprot/P31749 denotes Akt
T15057 279-282 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15056 212-215 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15059 604-607 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T15058 513-516 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt

UBERON-AE

Id Subject Object Predicate Lexical cue
T13693 1290-1295 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T13692 864-869 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T13691 741-746 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T13690 538-543 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

GO-BP

Id Subject Object Predicate Lexical cue
T13942 1444-1462 http://purl.obolibrary.org/obo/GO_0051668 denotes membrane localized
T13938 1195-1198 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T13927 1209-1224 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T13926 1088-1103 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T13921 1022-1027 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T13920 851-856 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T13915 1017-1027 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T13914 846-856 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T13912 398-410 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T13911 1546-1555 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T13910 1377-1386 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T13909 363-369 http://purl.obolibrary.org/obo/GO_0023052 denotes signal
T13908 1647-1653 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T13907 1532-1538 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T13906 178-184 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T13899 1741-1752 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T13898 1618-1629 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T13897 1515-1526 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T13896 1036-1047 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T13895 953-964 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T13894 726-737 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T13893 234-245 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T13885 1741-1752 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T13884 1618-1629 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T13883 1515-1526 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T13882 1036-1047 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T13881 953-964 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T13880 726-737 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T13879 234-245 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis

GO-MF

Id Subject Object Predicate Lexical cue
T13956 1195-1198 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK

GO-CC

Id Subject Object Predicate Lexical cue
T13974 1357-1361 http://purl.obolibrary.org/obo/GO_0097683 denotes apex
T13972 1444-1452 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T13971 425-433 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T13970 418-433 http://purl.obolibrary.org/obo/GO_0005886 denotes plasma membrane
T13966 686-691 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T13965 583-588 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T13964 13-18 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T13705 1557-1753 Sentence denotes RIP1 kinase was still able to regulate Akt activation during necroptosis, suggesting that growth factors and RIP1 kinase provide two independent inputs required for Akt changes during necroptosis.
T13704 1388-1556 Sentence denotes These data demonstrated that the presence of active and membrane localized Akt is sufficient to uncouple Akt activation during necroptosis from growth factor signaling.
T13703 1117-1387 Sentence denotes Myr-Akt also allowed other zVAD.fmk-dependent events, including activation of JNK and c-Jun phosphorylation (Fig. 7C) and upregulation of TNFα mRNA (Fig. 7D) to occur under serum free conditions, confirming an important role for Akt at the apex of necroptotic signaling.
T13702 978-1116 Sentence denotes Nec-1 prevented both Myr-Akt dependent cell death and the necroptosis-specific delayed increase in Akt Thr308 phosphorylation (Fig. 7B,C).
T13701 858-977 Sentence denotes Under serum free conditions Myr-Akt, but not the K179M mutant, fully restored zVAD.fmk-induced necroptosis (Fig. 7A,B).
T13700 769-857 Sentence denotes This indicates that active Akt alone is not sufficient to induce necroptotic cell death.
T13699 550-768 Sentence denotes It is important to note that the cells expressing Myr-Akt were viable, grew in a manner indistinguishable from the empty vector control cells, and were not triggered to induce necroptosis by serum starvation (Fig. 7B).
T13698 247-549 Sentence denotes Constitutively active Akt1 (Myr-Akt) was generated as previously described [37] by the addition of a myristoylation signal which provides constitutive localization to the plasma membrane and by the deletion of the auto-inhibitory PH domain (Fig. 7A) resulting in an Akt that is active under serum free.
T13697 0-246 Sentence denotes We used L929 cells stably expressing constitutively active wild type Akt1 (Myr-Akt) or the catalytically inactive mutant K179M in order to further understand the contribution of growth factors and RIP1 kinase to Akt activation during necroptosis.
T177 0-246 Sentence denotes We used L929 cells stably expressing constitutively active wild type Akt1 (Myr-Akt) or the catalytically inactive mutant K179M in order to further understand the contribution of growth factors and RIP1 kinase to Akt activation during necroptosis.
T178 247-549 Sentence denotes Constitutively active Akt1 (Myr-Akt) was generated as previously described [37] by the addition of a myristoylation signal which provides constitutive localization to the plasma membrane and by the deletion of the auto-inhibitory PH domain (Fig. 7A) resulting in an Akt that is active under serum free.
T179 550-768 Sentence denotes It is important to note that the cells expressing Myr-Akt were viable, grew in a manner indistinguishable from the empty vector control cells, and were not triggered to induce necroptosis by serum starvation (Fig. 7B).
T180 769-857 Sentence denotes This indicates that active Akt alone is not sufficient to induce necroptotic cell death.
T181 858-977 Sentence denotes Under serum free conditions Myr-Akt, but not the K179M mutant, fully restored zVAD.fmk-induced necroptosis (Fig. 7A,B).
T182 978-1116 Sentence denotes Nec-1 prevented both Myr-Akt dependent cell death and the necroptosis-specific delayed increase in Akt Thr308 phosphorylation (Fig. 7B,C).
T183 1117-1387 Sentence denotes Myr-Akt also allowed other zVAD.fmk-dependent events, including activation of JNK and c-Jun phosphorylation (Fig. 7C) and upregulation of TNFα mRNA (Fig. 7D) to occur under serum free conditions, confirming an important role for Akt at the apex of necroptotic signaling.
T184 1388-1556 Sentence denotes These data demonstrated that the presence of active and membrane localized Akt is sufficient to uncouple Akt activation during necroptosis from growth factor signaling.
T185 1557-1753 Sentence denotes RIP1 kinase was still able to regulate Akt activation during necroptosis, suggesting that growth factors and RIP1 kinase provide two independent inputs required for Akt changes during necroptosis.

simple1

Id Subject Object Predicate Lexical cue
T14031 1666-1670 Protein denotes RIP1
T14030 1557-1561 Protein denotes RIP1
T14029 1255-1259 Protein denotes TNFα
T14028 1203-1208 Protein denotes c-Jun
T14027 999-1006 Protein denotes Myr-Akt
T14026 907-912 Protein denotes K179M
T14025 886-893 Protein denotes Myr-Akt
T14024 600-607 Protein denotes Myr-Akt
T14023 275-282 Protein denotes Myr-Akt
T14022 269-273 Protein denotes Akt1
T14021 197-201 Protein denotes RIP1
T14020 121-126 Protein denotes K179M
T14019 75-82 Protein denotes Myr-Akt
T14018 69-73 Protein denotes Akt1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T14960 1239-1251 Positive_regulation denotes upregulation
T14959 1209-1224 Phosphorylation denotes phosphorylation
T14958 589-599 Gene_expression denotes expressing
T14957 26-36 Gene_expression denotes expressing
T14927 1666-1670 Protein denotes RIP1
T14926 1557-1561 Protein denotes RIP1
T14925 1255-1259 Protein denotes TNFα
T14924 1203-1208 Protein denotes c-Jun
T14923 999-1006 Protein denotes Myr-Akt
T14922 907-912 Protein denotes K179M
T14921 886-893 Protein denotes Myr-Akt
T14920 600-607 Protein denotes Myr-Akt
T14919 275-282 Protein denotes Myr-Akt
T14918 269-273 Protein denotes Akt1
T14917 197-201 Protein denotes RIP1
T14916 121-126 Protein denotes K179M
T14915 75-82 Protein denotes Myr-Akt
T14914 69-73 Protein denotes Akt1
R9911 T14914 T14957 themeOf Akt1,expressing
R9912 T14915 T14957 themeOf Myr-Akt,expressing
R9913 T14916 T14957 themeOf K179M,expressing
R9914 T14920 T14958 themeOf Myr-Akt,expressing
R9915 T14924 T14959 themeOf c-Jun,phosphorylation
R9916 T14925 T14960 themeOf TNFα,upregulation

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T15274 1239-1251 Positive_regulation denotes upregulation
T15273 1209-1224 Phosphorylation denotes phosphorylation
T15272 589-599 Gene_expression denotes expressing
T15241 1666-1670 Protein denotes RIP1
T15240 1557-1561 Protein denotes RIP1
T15239 1255-1259 Protein denotes TNFα
T15238 1203-1208 Protein denotes c-Jun
T15237 999-1006 Protein denotes Myr-Akt
T15236 907-912 Protein denotes K179M
T15235 886-893 Protein denotes Myr-Akt
T15234 600-607 Protein denotes Myr-Akt
T15233 275-282 Protein denotes Myr-Akt
T15232 269-273 Protein denotes Akt1
T15231 197-201 Protein denotes RIP1
T15230 121-126 Protein denotes K179M
T15229 75-82 Protein denotes Myr-Akt
T15228 69-73 Protein denotes Akt1
T15271 26-36 Gene_expression denotes expressing
R10009 T15228 T15271 themeOf Akt1,expressing
R10010 T15229 T15271 themeOf Myr-Akt,expressing
R10011 T15230 T15271 themeOf K179M,expressing
R10012 T15234 T15272 themeOf Myr-Akt,expressing
R10013 T15238 T15273 themeOf c-Jun,phosphorylation
R10014 T15239 T15274 themeOf TNFα,upregulation

DLUT931

Id Subject Object Predicate Lexical cue
T15148 1181-1191 Positive_regulation denotes activation
T15147 1239-1251 Positive_regulation denotes upregulation
T15146 1209-1224 Phosphorylation denotes phosphorylation
T15145 589-599 Gene_expression denotes expressing
T15144 26-36 Gene_expression denotes expressing
T15114 1666-1670 Protein denotes RIP1
T15113 1557-1561 Protein denotes RIP1
T15112 1255-1259 Protein denotes TNFα
T15111 1203-1208 Protein denotes c-Jun
T15110 999-1006 Protein denotes Myr-Akt
T15109 907-912 Protein denotes K179M
T15108 886-893 Protein denotes Myr-Akt
T15107 600-607 Protein denotes Myr-Akt
T15106 275-282 Protein denotes Myr-Akt
T15105 269-273 Protein denotes Akt1
T15104 197-201 Protein denotes RIP1
T15103 121-126 Protein denotes K179M
T15102 75-82 Protein denotes Myr-Akt
T15101 69-73 Protein denotes Akt1
R9949 T15101 T15144 themeOf Akt1,expressing
R9950 T15102 T15144 themeOf Myr-Akt,expressing
R9951 T15103 T15144 themeOf K179M,expressing
R9952 T15107 T15145 themeOf Myr-Akt,expressing
R9953 T15111 T15146 themeOf c-Jun,phosphorylation
R9954 T15112 T15147 themeOf TNFα,upregulation
R9981 T15146 T15148 themeOf phosphorylation,activation
R9982 T15146 T15147 themeOf phosphorylation,upregulation
R9983 T15147 T15148 themeOf upregulation,activation
R9984 T15147 T15148 themeOf upregulation,activation

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T15767 330-362 Positive_regulation denotes the addition of a myristoylation
T15766 1239-1264 Positive_regulation denotes upregulation of TNFα mRNA
T15765 1493-1507 Positive_regulation denotes Akt activation
T15759 579-607 Gene_expression denotes the cells expressing Myr-Akt
T15758 1596-1610 Positive_regulation denotes Akt activation
T15757 212-226 Positive_regulation denotes Akt activation
T15752 1074-1103 Phosphorylation denotes in Akt Thr308 phosphorylation
T15749 1532-1555 Positive_regulation denotes growth factor signaling
T15748 247-297 Gene_expression denotes Constitutively active Akt1 (Myr-Akt) was generated
T15746 1584-1629 Regulation denotes to regulate Akt activation during necroptosis
T15745 1138-1208 Positive_regulation denotes other zVAD.fmk-dependent events, including activation of JNK and c-Jun
T15744 1138-1208 Positive_regulation denotes other zVAD.fmk-dependent events, including activation of JNK and c-Jun
T15743 414-433 Entity denotes the plasma membrane
T15740 1117-1124 Protein denotes Myr-Akt
T15735 1444-1462 Entity denotes membrane localized
T15702 212-215 Protein denotes Akt
T15699 1144-1162 Entity denotes zVAD.fmk-dependent
T15697 1252-1264 Protein denotes of TNFα mRNA
T15694 1532-1545 Protein denotes growth factor
T15693 441-479 Protein denotes the deletion of the auto-inhibitory PH
T15690 1557-1561 Protein denotes RIP1
T15683 1255-1259 Protein denotes TNFα
T15682 999-1016 Protein denotes Myr-Akt dependent
T15681 52-83 Protein denotes active wild type Akt1 (Myr-Akt)
T15672 600-607 Protein denotes Myr-Akt
T15668 1203-1208 Protein denotes c-Jun
T15667 886-920 Entity denotes Myr-Akt, but not the K179M mutant,
T15660 1195-1198 Protein denotes JNK
T15659 661-691 Entity denotes the empty vector control cells
T15657 936-952 Entity denotes zVAD.fmk-induced
T15655 1353-1386 Entity denotes the apex of necroptotic signaling
T15653 105-126 Protein denotes inactive mutant K179M
T15651 1226-1229 Protein denotes Fig
T15649 1722-1725 Protein denotes Akt
T15643 1077-1080 Protein denotes Akt
T15641 1557-1568 Protein denotes RIP1 kinase
T15640 1077-1087 Entity denotes Akt Thr308
T15637 197-208 Protein denotes RIP1 kinase
T15634 262-283 Protein denotes active Akt1 (Myr-Akt)
T15633 75-82 Protein denotes Myr-Akt
T15627 1105-1108 Protein denotes Fig
T15624 197-201 Protein denotes RIP1
T15619 1346-1349 Protein denotes Akt
T15616 275-282 Protein denotes Myr-Akt
T15613 513-548 Protein denotes Akt that is active under serum free
T15606 1596-1599 Protein denotes Akt
T15730 579-607 Entity denotes the cells expressing Myr-Akt
T15729 784-799 Protein denotes that active Akt
T15725 1493-1496 Protein denotes Akt
T15724 1266-1269 Protein denotes Fig
T15722 480-496 Entity denotes domain (Fig. 7A)
T15721 1666-1677 Protein denotes RIP1 kinase
T15717 890-893 Protein denotes Akt
T15715 886-920 Entity denotes Myr-Akt, but not the K179M mutant,
T15712 1430-1466 Protein denotes of active and membrane localized Akt
T15710 1666-1670 Protein denotes RIP1
T15704 903-919 Protein denotes the K179M mutant
R10210 T15606 T15758 themeOf Akt,Akt activation
R10217 T15634 T15748 themeOf active Akt1 (Myr-Akt),Constitutively active Akt1 (Myr-Akt) was generated
R10218 T15640 T15643 partOf Akt Thr308,Akt
R10219 T15640 T15752 siteOf Akt Thr308,in Akt Thr308 phosphorylation
R10220 T15643 T15752 themeOf Akt,in Akt Thr308 phosphorylation
R10224 T15660 T15744 themeOf JNK,"other zVAD.fmk-dependent events, including activation of JNK and c-Jun"
R10226 T15668 T15745 themeOf c-Jun,"other zVAD.fmk-dependent events, including activation of JNK and c-Jun"
R10227 T15672 T15759 themeOf Myr-Akt,the cells expressing Myr-Akt
R10231 T15694 T15749 causeOf growth factor,growth factor signaling
R10232 T15697 T15766 themeOf of TNFα mRNA,upregulation of TNFα mRNA
R10233 T15702 T15757 themeOf Akt,Akt activation
R10238 T15725 T15765 themeOf Akt,Akt activation
R10243 T15758 T15746 themeOf Akt activation,to regulate Akt activation during necroptosis

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T16078 1752-1753 . denotes .
T16077 1741-1752 NN denotes necroptosis
T16076 1734-1740 IN denotes during
T16075 1726-1733 NNS denotes changes
T16074 1722-1725 NNP denotes Akt
T16073 1718-1721 IN denotes for
T16072 1709-1717 VBN denotes required
T16071 1702-1708 NNS denotes inputs
T16070 1690-1701 JJ denotes independent
T16069 1686-1689 CD denotes two
T16068 1678-1685 VBP denotes provide
T16067 1671-1677 NN denotes kinase
T16066 1666-1670 CD denotes RIP1
T16065 1662-1665 CC denotes and
T16064 1654-1661 NNS denotes factors
T16063 1647-1653 NN denotes growth
T16062 1642-1646 IN denotes that
T16061 1631-1641 VBG denotes suggesting
T16060 1629-1630 , denotes ,
T16059 1618-1629 NN denotes necroptosis
T16058 1611-1617 IN denotes during
T16057 1600-1610 NN denotes activation
T16056 1596-1599 NNP denotes Akt
T16055 1587-1595 VB denotes regulate
T16054 1584-1586 TO denotes to
T16053 1579-1583 JJ denotes able
T16052 1573-1578 RB denotes still
T16051 1569-1572 VBD denotes was
T16050 1562-1568 NN denotes kinase
T16049 1557-1561 CD denotes RIP1
T16048 1555-1556 . denotes .
T16047 1546-1555 VBG denotes signaling
T16046 1539-1545 NN denotes factor
T16045 1532-1538 NN denotes growth
T16044 1527-1531 IN denotes from
T16043 1515-1526 NN denotes necroptosis
T16042 1508-1514 IN denotes during
T16041 1497-1507 NN denotes activation
T16040 1493-1496 NNP denotes Akt
T16039 1484-1492 VB denotes uncouple
T16038 1481-1483 TO denotes to
T16037 1470-1480 JJ denotes sufficient
T16036 1467-1469 VBZ denotes is
T16035 1463-1466 NNP denotes Akt
T16034 1453-1462 VBN denotes localized
T16033 1444-1452 JJ denotes membrane
T16032 1440-1443 CC denotes and
T16031 1433-1439 JJ denotes active
T16030 1430-1432 IN denotes of
T16029 1421-1429 NN denotes presence
T16028 1417-1420 DT denotes the
T16027 1412-1416 IN denotes that
T16026 1399-1411 VBD denotes demonstrated
T16025 1394-1398 NNS denotes data
T16024 1388-1393 DT denotes These
T16023 1386-1387 . denotes .
T16022 1377-1386 VBG denotes signaling
T16021 1365-1376 JJ denotes necroptotic
T16020 1362-1364 IN denotes of
T16019 1357-1361 NN denotes apex
T16018 1353-1356 DT denotes the
T16017 1350-1352 IN denotes at
T16016 1346-1349 NNP denotes Akt
T16015 1342-1345 IN denotes for
T16014 1337-1341 NN denotes role
T16013 1327-1336 JJ denotes important
T16012 1324-1326 DT denotes an
T16011 1313-1323 VBG denotes confirming
T16010 1311-1312 , denotes ,
T16009 1301-1311 NNS denotes conditions
T16008 1296-1300 JJ denotes free
T16007 1290-1295 NN denotes serum
T16006 1284-1289 IN denotes under
T16005 1278-1283 VB denotes occur
T16004 1275-1277 TO denotes to
T16003 1273-1274 -RRB- denotes )
T16002 1271-1273 NNP denotes 7D
T16001 1266-1270 NNP denotes Fig.
T16000 1265-1266 -LRB- denotes (
T15999 1260-1264 NNP denotes mRNA
T15998 1255-1259 NNP denotes TNFα
T15997 1252-1254 IN denotes of
T15996 1239-1251 NN denotes upregulation
T15995 1235-1238 CC denotes and
T15994 1233-1234 -RRB- denotes )
T15993 1231-1233 NNP denotes 7C
T15992 1226-1230 NNP denotes Fig.
T15991 1225-1226 -LRB- denotes (
T15990 1209-1224 NN denotes phosphorylation
T15989 1203-1208 JJ denotes c-Jun
T15988 1199-1202 CC denotes and
T15987 1195-1198 NNP denotes JNK
T15986 1192-1194 IN denotes of
T15985 1181-1191 NN denotes activation
T15984 1171-1180 VBG denotes including
T15983 1169-1170 , denotes ,
T15982 1163-1169 NNS denotes events
T15981 1144-1162 JJ denotes zVAD.fmk-dependent
T15980 1138-1143 JJ denotes other
T15979 1130-1137 VBD denotes allowed
T15978 1125-1129 RB denotes also
T15977 1117-1124 NNP denotes Myr-Akt
T15976 1115-1116 . denotes .
T15975 1114-1115 -RRB- denotes )
T15974 1113-1114 NNP denotes C
T15973 1112-1113 , denotes ,
T15972 1110-1112 NN denotes 7B
T15971 1105-1109 NNP denotes Fig.
T15970 1104-1105 -LRB- denotes (
T15969 1088-1103 NN denotes phosphorylation
T15968 1081-1087 NNP denotes Thr308
T15967 1077-1080 NNP denotes Akt
T15966 1074-1076 IN denotes in
T15965 1065-1073 NN denotes increase
T15964 1057-1064 JJ denotes delayed
T15963 1036-1056 JJ denotes necroptosis-specific
T15962 1032-1035 DT denotes the
T15961 1028-1031 CC denotes and
T15960 1022-1027 NN denotes death
T15959 1017-1021 NN denotes cell
T15958 1007-1016 JJ denotes dependent
T15957 999-1006 NNP denotes Myr-Akt
T15956 994-998 DT denotes both
T15955 984-993 VBN denotes prevented
T15954 978-983 JJ denotes Nec-1
T15953 976-977 . denotes .
T15952 975-976 -RRB- denotes )
T15951 974-975 NNP denotes B
T15950 973-974 , denotes ,
T15949 971-973 NN denotes 7A
T15948 966-970 NNP denotes Fig.
T15947 965-966 -LRB- denotes (
T15946 953-964 NN denotes necroptosis
T15945 936-952 JJ denotes zVAD.fmk-induced
T15944 927-935 VBN denotes restored
T15943 921-926 RB denotes fully
T15942 919-920 , denotes ,
T15941 913-919 JJ denotes mutant
T15940 907-912 NNP denotes K179M
T15939 903-906 DT denotes the
T15938 899-902 RB denotes not
T15937 895-898 CC denotes but
T15936 893-894 , denotes ,
T15935 886-893 NNP denotes Myr-Akt
T15934 875-885 NNS denotes conditions
T15933 870-874 JJ denotes free
T15932 864-869 NN denotes serum
T15931 858-863 IN denotes Under
T15930 856-857 . denotes .
T15929 851-856 NN denotes death
T15928 846-850 NN denotes cell
T15927 834-845 JJ denotes necroptotic
T15926 827-833 VB denotes induce
T15925 824-826 TO denotes to
T15924 813-823 JJ denotes sufficient
T15923 809-812 RB denotes not
T15922 806-808 VBZ denotes is
T15921 800-805 RB denotes alone
T15920 796-799 NNP denotes Akt
T15919 789-795 JJ denotes active
T15918 784-788 IN denotes that
T15917 774-783 VBZ denotes indicates
T15916 769-773 DT denotes This
T15915 767-768 . denotes .
T15914 766-767 -RRB- denotes )
T15913 764-766 NN denotes 7B
T15912 759-763 NNP denotes Fig.
T15911 758-759 -LRB- denotes (
T15910 747-757 NN denotes starvation
T15909 741-746 NN denotes serum
T15908 738-740 IN denotes by
T15907 726-737 NN denotes necroptosis
T15906 719-725 VB denotes induce
T15905 716-718 TO denotes to
T15904 706-715 VBN denotes triggered
T15903 702-705 RB denotes not
T15902 697-701 VBD denotes were
T15901 693-696 CC denotes and
T15900 691-692 , denotes ,
T15899 686-691 NNS denotes cells
T15898 678-685 NN denotes control
T15897 671-677 NN denotes vector
T15896 665-670 JJ denotes empty
T15895 661-664 DT denotes the
T15894 656-660 IN denotes from
T15893 638-655 JJ denotes indistinguishable
T15892 631-637 NN denotes manner
T15891 629-630 DT denotes a
T15890 626-628 IN denotes in
T15889 621-625 VBD denotes grew
T15852 434-437 CC denotes and
T15851 425-433 NN denotes membrane
T15850 418-424 NN denotes plasma
T15849 414-417 DT denotes the
T15848 411-413 TO denotes to
T15847 398-410 NN denotes localization
T15846 385-397 JJ denotes constitutive
T15845 376-384 VBZ denotes provides
T15844 370-375 WDT denotes which
T15843 363-369 NN denotes signal
T15842 348-362 NN denotes myristoylation
T15841 346-347 DT denotes a
T15840 343-345 IN denotes of
T15839 334-342 NN denotes addition
T15838 330-333 DT denotes the
T15837 327-329 IN denotes by
T15836 325-326 NNP denotes ]
T15835 323-325 CD denotes 37
T15834 322-323 NNP denotes [
T15833 312-321 VBN denotes described
T15832 301-311 RB denotes previously
T15831 298-300 IN denotes as
T15830 288-297 VBN denotes generated
T15829 284-287 VBD denotes was
T15828 282-283 -RRB- denotes )
T15827 275-282 NNP denotes Myr-Akt
T15826 274-275 -LRB- denotes (
T15825 269-273 NNP denotes Akt1
T15824 262-268 JJ denotes active
T15823 247-261 RB denotes Constitutively
T15822 245-246 . denotes .
T15821 234-245 NN denotes necroptosis
T15820 227-233 IN denotes during
T15819 216-226 NN denotes activation
T15818 212-215 NNP denotes Akt
T15817 209-211 TO denotes to
T15816 202-208 NN denotes kinase
T15815 197-201 CD denotes RIP1
T15814 193-196 CC denotes and
T15813 185-192 NNS denotes factors
T15812 178-184 NN denotes growth
T15811 175-177 IN denotes of
T15810 162-174 NN denotes contribution
T15809 158-161 DT denotes the
T15808 147-157 VBP denotes understand
T15807 139-146 JJ denotes further
T15806 136-138 TO denotes to
T15805 130-135 NN denotes order
T15804 127-129 IN denotes in
T15803 121-126 NNP denotes K179M
T15802 114-120 JJ denotes mutant
T15801 105-113 JJ denotes inactive
T15800 91-104 RB denotes catalytically
T15799 87-90 DT denotes the
T15798 84-86 CC denotes or
T15797 82-83 -RRB- denotes )
T15796 75-82 NNP denotes Myr-Akt
T15795 74-75 -LRB- denotes (
T15794 69-73 NNP denotes Akt1
T15793 64-68 NN denotes type
T15792 59-63 JJ denotes wild
T15791 52-58 JJ denotes active
T15790 37-51 RB denotes constitutively
T15789 26-36 VBG denotes expressing
T15788 19-25 RB denotes stably
T15787 13-18 NNS denotes cells
T15786 8-12 CD denotes L929
T15785 3-7 VBD denotes used
T15784 0-2 PRP denotes We
T15888 619-620 , denotes ,
T15887 613-619 JJ denotes viable
T15886 608-612 VBD denotes were
T15885 600-607 NNP denotes Myr-Akt
T15884 589-599 VBG denotes expressing
T15883 583-588 NNS denotes cells
T15882 579-582 DT denotes the
T15881 574-578 IN denotes that
T15880 569-573 VB denotes note
T15879 566-568 TO denotes to
T15878 556-565 JJ denotes important
T15877 553-555 VBZ denotes is
T15876 550-552 PRP denotes It
T15875 548-549 . denotes .
T15874 544-548 JJ denotes free
T15873 538-543 NN denotes serum
T15872 532-537 IN denotes under
T15871 525-531 JJ denotes active
T15870 522-524 VBZ denotes is
T15869 517-521 WDT denotes that
T15868 513-516 NNP denotes Akt
T15867 510-512 DT denotes an
T15866 507-509 IN denotes in
T15865 497-506 VBG denotes resulting
T15864 495-496 -RRB- denotes )
T15863 493-495 NN denotes 7A
T15862 488-492 NNP denotes Fig.
T15861 487-488 -LRB- denotes (
T15860 480-486 NN denotes domain
T15859 477-479 NNP denotes PH
T15858 461-476 JJ denotes auto-inhibitory
T15857 457-460 DT denotes the
T15856 454-456 IN denotes of
T15855 445-453 NN denotes deletion
T15854 441-444 DT denotes the
T15853 438-440 IN denotes by
R10256 T15784 T15785 nsubj We,used
R10257 T15785 T15785 ROOT used,used
R10258 T15786 T15787 nummod L929,cells
R10259 T15787 T15785 dobj cells,used
R10260 T15788 T15789 advmod stably,expressing
R10261 T15789 T15785 advcl expressing,used
R10262 T15790 T15791 advmod constitutively,active
R10263 T15791 T15793 amod active,type
R10264 T15792 T15793 amod wild,type
R10265 T15793 T15789 dobj type,expressing
R10266 T15794 T15793 appos Akt1,type
R10267 T15795 T15796 punct (,Myr-Akt
R10268 T15796 T15794 appos Myr-Akt,Akt1
R10269 T15797 T15796 punct ),Myr-Akt
R10270 T15798 T15794 cc or,Akt1
R10271 T15799 T15803 det the,K179M
R10272 T15800 T15801 advmod catalytically,inactive
R10273 T15801 T15803 amod inactive,K179M
R10274 T15802 T15803 compound mutant,K179M
R10275 T15803 T15794 conj K179M,Akt1
R10276 T15804 T15789 prep in,expressing
R10277 T15805 T15804 pobj order,in
R10278 T15806 T15808 aux to,understand
R10279 T15807 T15808 advmod further,understand
R10280 T15808 T15805 acl understand,order
R10281 T15809 T15810 det the,contribution
R10282 T15810 T15808 dobj contribution,understand
R10283 T15811 T15810 prep of,contribution
R10284 T15812 T15813 compound growth,factors
R10285 T15813 T15811 pobj factors,of
R10286 T15814 T15813 cc and,factors
R10287 T15815 T15816 nummod RIP1,kinase
R10288 T15816 T15813 conj kinase,factors
R10289 T15817 T15816 prep to,kinase
R10290 T15818 T15819 compound Akt,activation
R10291 T15819 T15817 pobj activation,to
R10292 T15820 T15816 prep during,kinase
R10293 T15821 T15820 pobj necroptosis,during
R10294 T15822 T15785 punct .,used
R10295 T15823 T15824 advmod Constitutively,active
R10296 T15824 T15825 amod active,Akt1
R10297 T15825 T15830 nsubjpass Akt1,generated
R10298 T15826 T15827 punct (,Myr-Akt
R10299 T15827 T15825 appos Myr-Akt,Akt1
R10300 T15828 T15825 punct ),Akt1
R10301 T15829 T15830 auxpass was,generated
R10302 T15830 T15830 ROOT generated,generated
R10303 T15831 T15833 mark as,described
R10304 T15832 T15833 advmod previously,described
R10305 T15833 T15830 advcl described,generated
R10306 T15834 T15836 nmod [,]
R10307 T15835 T15836 nummod 37,]
R10308 T15836 T15833 dobj ],described
R10309 T15837 T15833 prep by,described
R10310 T15838 T15839 det the,addition
R10311 T15839 T15837 pobj addition,by
R10312 T15840 T15839 prep of,addition
R10313 T15841 T15843 det a,signal
R10314 T15842 T15843 compound myristoylation,signal
R10315 T15843 T15840 pobj signal,of
R10316 T15844 T15845 nsubj which,provides
R10317 T15845 T15843 relcl provides,signal
R10318 T15846 T15847 amod constitutive,localization
R10319 T15847 T15845 dobj localization,provides
R10320 T15848 T15845 dative to,provides
R10321 T15849 T15851 det the,membrane
R10322 T15850 T15851 compound plasma,membrane
R10323 T15851 T15848 pobj membrane,to
R10324 T15852 T15845 cc and,provides
R10325 T15853 T15843 prep by,signal
R10326 T15854 T15855 det the,deletion
R10327 T15855 T15853 pobj deletion,by
R10328 T15856 T15855 prep of,deletion
R10329 T15857 T15860 det the,domain
R10330 T15858 T15860 amod auto-inhibitory,domain
R10331 T15859 T15860 compound PH,domain
R10332 T15860 T15856 pobj domain,of
R10333 T15861 T15860 punct (,domain
R10334 T15862 T15863 compound Fig.,7A
R10335 T15863 T15860 appos 7A,domain
R10336 T15864 T15860 punct ),domain
R10337 T15865 T15833 advcl resulting,described
R10338 T15866 T15865 prep in,resulting
R10339 T15867 T15868 det an,Akt
R10340 T15868 T15866 pobj Akt,in
R10341 T15869 T15870 nsubj that,is
R10342 T15870 T15868 relcl is,Akt
R10343 T15871 T15870 acomp active,is
R10344 T15872 T15870 prep under,is
R10345 T15873 T15874 npadvmod serum,free
R10346 T15874 T15870 acomp free,is
R10347 T15875 T15830 punct .,generated
R10348 T15876 T15877 nsubj It,is
R10349 T15877 T15877 ROOT is,is
R10350 T15878 T15877 acomp important,is
R10351 T15879 T15880 aux to,note
R10352 T15880 T15877 xcomp note,is
R10353 T15881 T15886 mark that,were
R10354 T15882 T15883 det the,cells
R10355 T15883 T15886 nsubj cells,were
R10356 T15884 T15883 acl expressing,cells
R10357 T15885 T15884 dobj Myr-Akt,expressing
R10358 T15886 T15880 ccomp were,note
R10359 T15887 T15886 acomp viable,were
R10360 T15888 T15889 punct ",",grew
R10361 T15889 T15886 conj grew,were
R10362 T15890 T15889 prep in,grew
R10363 T15891 T15892 det a,manner
R10364 T15892 T15890 pobj manner,in
R10365 T15893 T15892 amod indistinguishable,manner
R10366 T15894 T15893 prep from,indistinguishable
R10367 T15895 T15899 det the,cells
R10368 T15896 T15899 amod empty,cells
R10369 T15897 T15898 compound vector,control
R10370 T15898 T15899 compound control,cells
R10371 T15899 T15894 pobj cells,from
R10372 T15900 T15889 punct ",",grew
R10373 T15901 T15889 cc and,grew
R10374 T15902 T15904 auxpass were,triggered
R10375 T15903 T15904 neg not,triggered
R10376 T15904 T15889 conj triggered,grew
R10377 T15905 T15906 aux to,induce
R10378 T15906 T15904 xcomp induce,triggered
R10379 T15907 T15906 dobj necroptosis,induce
R10380 T15908 T15906 prep by,induce
R10381 T15909 T15910 compound serum,starvation
R10382 T15910 T15908 pobj starvation,by
R10383 T15911 T15910 punct (,starvation
R10384 T15912 T15913 compound Fig.,7B
R10385 T15913 T15910 appos 7B,starvation
R10386 T15914 T15910 punct ),starvation
R10387 T15915 T15877 punct .,is
R10388 T15916 T15917 nsubj This,indicates
R10389 T15917 T15917 ROOT indicates,indicates
R10390 T15918 T15922 mark that,is
R10391 T15919 T15920 amod active,Akt
R10392 T15920 T15922 nsubj Akt,is
R10393 T15921 T15920 advmod alone,Akt
R10394 T15922 T15917 ccomp is,indicates
R10395 T15923 T15922 neg not,is
R10396 T15924 T15922 acomp sufficient,is
R10397 T15925 T15926 aux to,induce
R10398 T15926 T15924 xcomp induce,sufficient
R10399 T15927 T15929 amod necroptotic,death
R10400 T15928 T15929 compound cell,death
R10401 T15929 T15926 dobj death,induce
R10402 T15930 T15917 punct .,indicates
R10403 T15931 T15941 prep Under,mutant
R10404 T15932 T15934 amod serum,conditions
R10405 T15933 T15934 amod free,conditions
R10406 T15934 T15931 pobj conditions,Under
R10407 T15935 T15941 dep Myr-Akt,mutant
R10408 T15936 T15941 punct ",",mutant
R10409 T15937 T15941 cc but,mutant
R10410 T15938 T15941 neg not,mutant
R10411 T15939 T15941 det the,mutant
R10412 T15940 T15941 compound K179M,mutant
R10413 T15941 T15941 ROOT mutant,mutant
R10414 T15942 T15946 punct ",",necroptosis
R10415 T15943 T15944 advmod fully,restored
R10416 T15944 T15946 amod restored,necroptosis
R10417 T15945 T15946 amod zVAD.fmk-induced,necroptosis
R10418 T15946 T15941 appos necroptosis,mutant
R10419 T15947 T15949 punct (,7A
R10420 T15948 T15949 compound Fig.,7A
R10421 T15949 T15946 appos 7A,necroptosis
R10422 T15950 T15949 punct ",",7A
R10423 T15951 T15949 appos B,7A
R10424 T15952 T15949 punct ),7A
R10425 T15953 T15941 punct .,mutant
R10426 T15954 T15955 nsubj Nec-1,prevented
R10427 T15955 T15955 ROOT prevented,prevented
R10428 T15956 T15960 det both,death
R10429 T15957 T15960 nmod Myr-Akt,death
R10430 T15958 T15960 amod dependent,death
R10431 T15959 T15960 compound cell,death
R10432 T15960 T15955 dobj death,prevented
R10433 T15961 T15960 cc and,death
R10434 T15962 T15965 det the,increase
R10435 T15963 T15965 amod necroptosis-specific,increase
R10436 T15964 T15965 amod delayed,increase
R10437 T15965 T15960 conj increase,death
R10438 T15966 T15965 prep in,increase
R10439 T15967 T15969 compound Akt,phosphorylation
R10440 T15968 T15969 compound Thr308,phosphorylation
R10441 T15969 T15966 pobj phosphorylation,in
R10442 T15970 T15972 punct (,7B
R10443 T15971 T15972 compound Fig.,7B
R10444 T15972 T15969 appos 7B,phosphorylation
R10445 T15973 T15972 punct ",",7B
R10446 T15974 T15972 appos C,7B
R10447 T15975 T15972 punct ),7B
R10448 T15976 T15955 punct .,prevented
R10449 T15977 T15979 nsubj Myr-Akt,allowed
R10450 T15978 T15979 advmod also,allowed
R10451 T15979 T15979 ROOT allowed,allowed
R10452 T15980 T15982 amod other,events
R10453 T15981 T15982 amod zVAD.fmk-dependent,events
R10454 T15982 T16005 nsubj events,occur
R10455 T15983 T15982 punct ",",events
R10456 T15984 T15982 prep including,events
R10457 T15985 T15984 pobj activation,including
R10458 T15986 T15985 prep of,activation
R10459 T15987 T15990 nmod JNK,phosphorylation
R10460 T15988 T15987 cc and,JNK
R10461 T15989 T15990 amod c-Jun,phosphorylation
R10462 T15990 T15986 pobj phosphorylation,of
R10463 T15991 T15993 punct (,7C
R10464 T15992 T15993 compound Fig.,7C
R10465 T15993 T15990 appos 7C,phosphorylation
R10466 T15994 T15993 punct ),7C
R10467 T15995 T15990 cc and,phosphorylation
R10468 T15996 T15990 conj upregulation,phosphorylation
R10469 T15997 T15990 prep of,phosphorylation
R10470 T15998 T15999 compound TNFα,mRNA
R10471 T15999 T15997 pobj mRNA,of
R10472 T16000 T15999 punct (,mRNA
R10473 T16001 T16002 compound Fig.,7D
R10474 T16002 T15999 appos 7D,mRNA
R10475 T16003 T15999 punct ),mRNA
R10476 T16004 T16005 aux to,occur
R10477 T16005 T15979 ccomp occur,allowed
R10478 T16006 T16005 prep under,occur
R10479 T16007 T16009 amod serum,conditions
R10480 T16008 T16009 amod free,conditions
R10481 T16009 T16006 pobj conditions,under
R10482 T16010 T15979 punct ",",allowed
R10483 T16011 T15979 advcl confirming,allowed
R10484 T16012 T16014 det an,role
R10485 T16013 T16014 amod important,role
R10486 T16014 T16011 dobj role,confirming
R10487 T16015 T16014 prep for,role
R10488 T16016 T16015 pobj Akt,for
R10489 T16017 T16014 prep at,role
R10490 T16018 T16019 det the,apex
R10491 T16019 T16017 pobj apex,at
R10492 T16020 T16019 prep of,apex
R10493 T16021 T16022 amod necroptotic,signaling
R10494 T16022 T16020 pobj signaling,of
R10495 T16023 T15979 punct .,allowed
R10496 T16024 T16025 det These,data
R10497 T16025 T16026 nsubj data,demonstrated
R10498 T16026 T16026 ROOT demonstrated,demonstrated
R10499 T16027 T16036 mark that,is
R10500 T16028 T16029 det the,presence
R10501 T16029 T16036 nsubj presence,is
R10502 T16030 T16029 prep of,presence
R10503 T16031 T16035 amod active,Akt
R10504 T16032 T16031 cc and,active
R10505 T16033 T16031 conj membrane,active
R10506 T16034 T16035 amod localized,Akt
R10507 T16035 T16030 pobj Akt,of
R10508 T16036 T16026 ccomp is,demonstrated
R10509 T16037 T16036 acomp sufficient,is
R10510 T16038 T16039 aux to,uncouple
R10511 T16039 T16037 xcomp uncouple,sufficient
R10512 T16040 T16041 compound Akt,activation
R10513 T16041 T16039 dobj activation,uncouple
R10514 T16042 T16039 prep during,uncouple
R10515 T16043 T16042 pobj necroptosis,during
R10516 T16044 T16043 prep from,necroptosis
R10517 T16045 T16046 compound growth,factor
R10518 T16046 T16044 pobj factor,from
R10519 T16047 T16036 advcl signaling,is
R10520 T16048 T16026 punct .,demonstrated
R10521 T16049 T16050 nummod RIP1,kinase
R10522 T16050 T16051 nsubj kinase,was
R10523 T16051 T16051 ROOT was,was
R10524 T16052 T16051 advmod still,was
R10525 T16053 T16051 acomp able,was
R10526 T16054 T16055 aux to,regulate
R10527 T16055 T16053 xcomp regulate,able
R10528 T16056 T16057 compound Akt,activation
R10529 T16057 T16055 dobj activation,regulate
R10530 T16058 T16055 prep during,regulate
R10531 T16059 T16058 pobj necroptosis,during
R10532 T16060 T16051 punct ",",was
R10533 T16061 T16051 advcl suggesting,was
R10534 T16062 T16068 mark that,provide
R10535 T16063 T16064 compound growth,factors
R10536 T16064 T16068 nsubj factors,provide
R10537 T16065 T16064 cc and,factors
R10538 T16066 T16067 nummod RIP1,kinase
R10539 T16067 T16064 conj kinase,factors
R10540 T16068 T16061 ccomp provide,suggesting
R10541 T16069 T16071 nummod two,inputs
R10542 T16070 T16071 amod independent,inputs
R10543 T16071 T16068 dobj inputs,provide
R10544 T16072 T16071 acl required,inputs
R10545 T16073 T16072 prep for,required
R10546 T16074 T16075 compound Akt,changes
R10547 T16075 T16073 pobj changes,for
R10548 T16076 T16075 prep during,changes
R10549 T16077 T16076 pobj necroptosis,during
R10550 T16078 T16051 punct .,was

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T15343 1587-1595 Regulation denotes regulate
T15342 1600-1610 Positive_regulation denotes activation
T15341 1666-1677 Protein denotes RIP1 kinase
T15340 1596-1599 Protein denotes Akt
T15339 1557-1568 Protein denotes RIP1 kinase
T15338 1484-1492 Positive_regulation denotes uncouple
T15337 1497-1507 Positive_regulation denotes activation
T15336 1493-1496 Protein denotes Akt
T15313 604-607 Protein denotes Akt
T15312 600-603 Protein denotes Myr
T15311 398-410 Localization denotes localization
T15310 262-268 Positive_regulation denotes active
T15309 262-268 Positive_regulation denotes active
T15308 279-282 Protein denotes Akt
T15307 275-278 Protein denotes Myr
T15306 269-273 Protein denotes Akt1
T15305 162-174 Positive_regulation denotes contribution
T15304 216-226 Positive_regulation denotes activation
T15303 52-58 Positive_regulation denotes active
T15302 52-58 Positive_regulation denotes active
T15301 26-36 Gene_expression denotes expressing
T15300 26-36 Gene_expression denotes expressing
T15299 26-36 Gene_expression denotes expressing
T15298 212-215 Protein denotes Akt
T15297 197-208 Protein denotes RIP1 kinase
T15296 79-82 Protein denotes Akt
T15295 75-78 Protein denotes Myr
T15294 59-73 Protein denotes wild type Akt1
T15335 1463-1466 Protein denotes Akt
T15334 1181-1191 Positive_regulation denotes activation
T15333 1239-1251 Positive_regulation denotes upregulation
T15332 1209-1224 Phosphorylation denotes phosphorylation
T15331 1181-1191 Positive_regulation denotes activation
T15330 1346-1349 Protein denotes Akt
T15329 1266-1269 Protein denotes Fig
T15328 1255-1264 Protein denotes TNFα mRNA
T15327 1203-1208 Protein denotes c-Jun
T15326 1195-1198 Protein denotes JNK
T15325 1121-1124 Protein denotes Akt
T15324 1117-1120 Protein denotes Myr
T15323 984-993 Negative_regulation denotes prevented
T15322 1065-1073 Positive_regulation denotes increase
T15321 1088-1103 Phosphorylation denotes phosphorylation
T15320 1077-1080 Protein denotes Akt
T15319 1003-1006 Protein denotes Akt
T15318 999-1002 Protein denotes Myr
T15317 978-983 Protein denotes Nec-1
T15316 796-799 Protein denotes Akt
T15315 589-599 Gene_expression denotes expressing
T15314 589-599 Gene_expression denotes expressing
R10042 T15294 T15299 themeOf wild type Akt1,expressing
R10043 T15294 T15302 themeOf wild type Akt1,active
R10044 T15295 T15300 themeOf Myr,expressing
R10045 T15296 T15301 themeOf Akt,expressing
R10046 T15296 T15303 themeOf Akt,active
R10047 T15298 T15304 themeOf Akt,activation
R10048 T15304 T15305 themeOf activation,contribution
R10049 T15306 T15309 themeOf Akt1,active
R10050 T15308 T15310 themeOf Akt,active
R10051 T15308 T15311 themeOf Akt,localization
R10052 T15312 T15314 themeOf Myr,expressing
R10053 T15313 T15315 themeOf Akt,expressing
R10054 T15317 T15323 causeOf Nec-1,prevented
R10055 T15320 T15321 themeOf Akt,phosphorylation
R10056 T15321 T15322 themeOf phosphorylation,increase
R10057 T15322 T15323 themeOf increase,prevented
R10058 T15326 T15331 themeOf JNK,activation
R10059 T15327 T15332 themeOf c-Jun,phosphorylation
R10060 T15328 T15333 themeOf TNFα mRNA,upregulation
R10061 T15329 T15333 causeOf Fig,upregulation
R10062 T15332 T15334 themeOf phosphorylation,activation
R10063 T15336 T15337 themeOf Akt,activation
R10064 T15337 T15338 themeOf activation,uncouple
R10065 T15339 T15343 causeOf RIP1 kinase,regulate
R10066 T15340 T15342 themeOf Akt,activation
R10067 T15342 T15343 themeOf activation,regulate

test3

Id Subject Object Predicate Lexical cue
T13623 1709-1717 Positive_regulation denotes required
T13622 1666-1670 Protein denotes RIP1
T13621 1600-1610 Positive_regulation denotes activation
T13620 1587-1595 Regulation denotes regulate
T13619 1557-1561 Protein denotes RIP1
T13618 1497-1507 Positive_regulation denotes activation
T13617 1337-1341 Regulation denotes role
T13616 1255-1259 Protein denotes TNFα
T13615 1239-1251 Positive_regulation denotes upregulation
T13614 1209-1224 Phosphorylation denotes phosphorylation
T13613 1203-1208 Protein denotes c-Jun
T13612 1088-1103 Phosphorylation denotes phosphorylation
T13611 1065-1073 Positive_regulation denotes increase
T13610 999-1006 Protein denotes Myr-Akt
T13609 907-912 Protein denotes K179M
T13608 886-893 Protein denotes Myr-Akt
T13607 600-607 Protein denotes Myr-Akt
T13606 589-599 Gene_expression denotes expressing
T13605 497-506 Positive_regulation denotes resulting
T13604 275-282 Protein denotes Myr-Akt
T13603 269-273 Protein denotes Akt1
T13602 216-226 Positive_regulation denotes activation
T13601 197-201 Protein denotes RIP1
T13600 121-126 Protein denotes K179M
T13599 75-82 Protein denotes Myr-Akt
T13598 69-73 Protein denotes Akt1
T13597 26-36 Gene_expression denotes expressing
T13565 1666-1670 Protein denotes RIP1
T13564 1557-1561 Protein denotes RIP1
T13563 1255-1259 Protein denotes TNFα
T13562 1203-1208 Protein denotes c-Jun
T13561 999-1006 Protein denotes Myr-Akt
T13560 907-912 Protein denotes K179M
T13559 886-893 Protein denotes Myr-Akt
T13558 600-607 Protein denotes Myr-Akt
T13557 275-282 Protein denotes Myr-Akt
T13556 269-273 Protein denotes Akt1
T13555 197-201 Protein denotes RIP1
T13554 121-126 Protein denotes K179M
T13553 75-82 Protein denotes Myr-Akt
T13552 69-73 Protein denotes Akt1
R8933 T13616 T13615 themeOf TNFα,upregulation
R8934 T13621 T13620 themeOf activation,regulate
R8927 T13598 T13597 themeOf Akt1,expressing
R8928 T13599 T13598 equivalentTo Myr-Akt,Akt1
R8929 T13604 T13603 equivalentTo Myr-Akt,Akt1
R8930 T13607 T13606 themeOf Myr-Akt,expressing
R8931 T13612 T13611 themeOf phosphorylation,increase
R8932 T13613 T13614 themeOf c-Jun,phosphorylation