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PMC:3585731 / 27517-27736
Annnotations
testone
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12716 | 189-199 | Positive_regulation | denotes | activation |
T12715 | 158-166 | Positive_regulation | denotes | required |
T12714 | 86-101 | Phosphorylation | denotes | phosphorylation |
T12713 | 65-74 | Negative_regulation | denotes | inhibited |
T12712 | 16-25 | Negative_regulation | denotes | knockdown |
T12696 | 135-139 | Protein | denotes | PDK1 |
T12695 | 29-33 | Protein | denotes | PDK1 |
R8395 | T12695 | T12712 | themeOf | PDK1,knockdown |
R8396 | T12696 | T12715 | causeOf | PDK1,required |
R8403 | T12712 | T12713 | causeOf | knockdown,inhibited |
R8404 | T12714 | T12713 | themeOf | phosphorylation,inhibited |
R8405 | T12716 | T12715 | themeOf | activation,required |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13002 | 207-218 | NN | denotes | necroptosis |
T13001 | 200-206 | IN | denotes | during |
T13000 | 189-199 | NN | denotes | activation |
T12999 | 185-188 | NN | denotes | Akt |
T12998 | 171-184 | JJ | denotes | non-canonical |
T12997 | 167-170 | IN | denotes | for |
T12996 | 158-166 | VB | denotes | required |
T12995 | 152-157 | RB | denotes | still |
T12994 | 149-151 | VB | denotes | is |
T12993 | 140-148 | NN | denotes | activity |
T12992 | 135-139 | NN | denotes | PDK1 |
T12991 | 131-134 | CC | denotes | and |
T12990 | 126-130 | NN | denotes | PI3K |
T12989 | 124-125 | -COMMA- | denotes | , |
T12988 | 115-124 | RB | denotes | Therefore |
T12987 | 113-114 | -RRB- | denotes | ) |
T12986 | 112-113 | NN | denotes | F |
T12985 | 111-112 | -COMMA- | denotes | , |
T12984 | 108-111 | NN | denotes | S7E |
T12983 | 103-107 | NNP | denotes | Fig. |
T12982 | 102-103 | -LRB- | denotes | ( |
T12981 | 86-101 | NN | denotes | phosphorylation |
T12980 | 79-85 | NN | denotes | Thr308 |
T12979 | 75-78 | NN | denotes | Akt |
T12978 | 65-74 | VB | denotes | inhibited |
T12977 | 61-64 | CC | denotes | and |
T12976 | 55-60 | NN | denotes | death |
T12975 | 50-54 | IN | denotes | from |
T12974 | 44-49 | NN | denotes | cells |
T12973 | 34-43 | VB | denotes | protected |
T12972 | 29-33 | NN | denotes | PDK1 |
T12971 | 26-28 | IN | denotes | of |
T12970 | 16-25 | NN | denotes | knockdown |
T12969 | 10-15 | NN | denotes | siRNA |
T12968 | 8-9 | -COMMA- | denotes | , |
T12967 | 0-8 | RB | denotes | Likewise |
R8560 | T12970 | T12969 | arg1Of | knockdown,siRNA |
R8561 | T12970 | T12971 | arg1Of | knockdown,of |
R8562 | T12970 | T12973 | arg1Of | knockdown,protected |
R8563 | T12970 | T12978 | arg1Of | knockdown,inhibited |
R8564 | T12972 | T12971 | arg2Of | PDK1,of |
R8565 | T12973 | T12975 | arg1Of | protected,from |
R8566 | T12973 | T12977 | arg1Of | protected,and |
R8567 | T12974 | T12973 | arg2Of | cells,protected |
R8568 | T12976 | T12975 | arg2Of | death,from |
R8569 | T12977 | T12989 | arg1Of | and,"," |
R8570 | T12978 | T12977 | arg2Of | inhibited,and |
R8571 | T12978 | T12988 | arg1Of | inhibited,Therefore |
R8572 | T12981 | T12978 | arg2Of | phosphorylation,inhibited |
R8573 | T12981 | T12979 | arg1Of | phosphorylation,Akt |
R8574 | T12981 | T12980 | arg1Of | phosphorylation,Thr308 |
R8575 | T12981 | T12982 | arg1Of | phosphorylation,( |
R8576 | T12984 | T12982 | arg2Of | S7E,( |
R8577 | T12984 | T12983 | arg1Of | S7E,Fig. |
R8578 | T12984 | T12985 | arg1Of | S7E,"," |
R8579 | T12986 | T12985 | arg2Of | F,"," |
R8580 | T12987 | T12982 | arg3Of | ),( |
R8581 | T12989 | T12967 | arg1Of | ",",Likewise |
R8582 | T12989 | T12968 | arg1Of | ",","," |
R8583 | T12990 | T12991 | arg1Of | PI3K,and |
R8584 | T12991 | T12994 | arg1Of | and,is |
R8585 | T12991 | T12996 | arg2Of | and,required |
R8586 | T12993 | T12991 | arg2Of | activity,and |
R8587 | T12993 | T12992 | arg1Of | activity,PDK1 |
R8588 | T12996 | T12989 | arg2Of | required,"," |
R8589 | T12996 | T12994 | arg2Of | required,is |
R8590 | T12996 | T12995 | arg1Of | required,still |
R8591 | T12996 | T12997 | arg1Of | required,for |
R8592 | T13000 | T12997 | arg2Of | activation,for |
R8593 | T13000 | T12998 | arg1Of | activation,non-canonical |
R8594 | T13000 | T12999 | arg1Of | activation,Akt |
R8595 | T13000 | T13001 | arg1Of | activation,during |
R8596 | T13002 | T13001 | arg2Of | necroptosis,during |
bionlp-st-ge-2016-test-proteins
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12768 | 135-139 | Protein | denotes | PDK1 |
T12767 | 29-33 | Protein | denotes | PDK1 |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13216 | 75-78 | http://www.uniprot.org/uniprot/P31751 | denotes | Akt |
T13209 | 185-188 | http://www.uniprot.org/uniprot/P31749 | denotes | Akt |
T13208 | 75-78 | http://www.uniprot.org/uniprot/P31749 | denotes | Akt |
T13225 | 185-188 | http://www.uniprot.org/uniprot/Q9Y243 | denotes | Akt |
T13224 | 75-78 | http://www.uniprot.org/uniprot/Q9Y243 | denotes | Akt |
T13217 | 185-188 | http://www.uniprot.org/uniprot/P31751 | denotes | Akt |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12794 | 55-60 | http://purl.obolibrary.org/obo/GO_0016265 | denotes | death |
T12788 | 207-218 | http://purl.obolibrary.org/obo/GO_0097528 | denotes | necroptosis |
T12786 | 207-218 | http://purl.obolibrary.org/obo/GO_0070266 | denotes | necroptosis |
T12784 | 126-130 | http://purl.obolibrary.org/obo/GO_0016303 | denotes | PI3K |
T12778 | 86-101 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T12774 | 135-139 | http://purl.obolibrary.org/obo/GO_0004740 | denotes | PDK1 |
T12773 | 29-33 | http://purl.obolibrary.org/obo/GO_0004740 | denotes | PDK1 |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12805 | 126-130 | http://purl.obolibrary.org/obo/GO_0016303 | denotes | PI3K |
T12800 | 135-139 | http://purl.obolibrary.org/obo/GO_0004740 | denotes | PDK1 |
T12799 | 29-33 | http://purl.obolibrary.org/obo/GO_0004740 | denotes | PDK1 |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12811 | 44-49 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12752 | 0-219 | Sentence | denotes | Likewise, siRNA knockdown of PDK1 protected cells from death and inhibited Akt Thr308 phosphorylation (Fig. S7E,F) Therefore, PI3K and PDK1 activity is still required for non-canonical Akt activation during necroptosis. |
T175 | 0-219 | Sentence | denotes | Likewise, siRNA knockdown of PDK1 protected cells from death and inhibited Akt Thr308 phosphorylation (Fig. S7E,F) Therefore, PI3K and PDK1 activity is still required for non-canonical Akt activation during necroptosis. |
simple1
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12825 | 135-139 | Protein | denotes | PDK1 |
T12824 | 29-33 | Protein | denotes | PDK1 |
BioNLP16_DUT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13168 | 16-25 | Negative_regulation | denotes | knockdown |
T13167 | 158-166 | Positive_regulation | denotes | required |
T13164 | 135-139 | Protein | denotes | PDK1 |
T13163 | 29-33 | Protein | denotes | PDK1 |
R8754 | T13163 | T13168 | themeOf | PDK1,knockdown |
R8755 | T13164 | T13167 | themeOf | PDK1,required |
BioNLP16_Messiy
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13264 | 16-25 | Negative_regulation | denotes | knockdown |
T13260 | 135-139 | Protein | denotes | PDK1 |
T13259 | 29-33 | Protein | denotes | PDK1 |
R8805 | T13259 | T13264 | themeOf | PDK1,knockdown |
DLUT931
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13237 | 158-166 | Positive_regulation | denotes | required |
T13236 | 16-25 | Negative_regulation | denotes | knockdown |
T13232 | 135-139 | Protein | denotes | PDK1 |
T13231 | 29-33 | Protein | denotes | PDK1 |
R8792 | T13231 | T13236 | themeOf | PDK1,knockdown |
R8793 | T13232 | T13237 | themeOf | PDK1,required |
bionlp-st-ge-2016-test-ihmc
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13401 | 171-218 | Positive_regulation | denotes | non-canonical Akt activation during necroptosis |
T13395 | 65-101 | Phosphorylation | denotes | inhibited Akt Thr308 phosphorylation |
T13394 | 65-101 | Negative_regulation | denotes | inhibited Akt Thr308 phosphorylation |
T13390 | 75-85 | Entity | denotes | Akt Thr308 |
T13389 | 10-12 | Entity | denotes | si |
T13387 | 135-139 | Protein | denotes | PDK1 |
T13380 | 29-33 | Protein | denotes | PDK1 |
T13375 | 103-106 | Protein | denotes | Fig |
T13374 | 75-78 | Protein | denotes | Akt |
T13363 | 26-101 | Entity | denotes | of PDK1 protected cells from death and inhibited Akt Thr308 phosphorylation |
T13360 | 185-188 | Protein | denotes | Akt |
T13359 | 12-15 | Protein | denotes | RNA |
R8868 | T13360 | T13401 | themeOf | Akt,non-canonical Akt activation during necroptosis |
R8874 | T13374 | T13395 | themeOf | Akt,inhibited Akt Thr308 phosphorylation |
R8882 | T13390 | T13374 | partOf | Akt Thr308,Akt |
R8883 | T13390 | T13395 | siteOf | Akt Thr308,inhibited Akt Thr308 phosphorylation |
R8888 | T13395 | T13394 | themeOf | inhibited Akt Thr308 phosphorylation,inhibited Akt Thr308 phosphorylation |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13201 | 218-219 | . | denotes | . |
T13200 | 207-218 | NN | denotes | necroptosis |
T13199 | 200-206 | IN | denotes | during |
T13198 | 189-199 | NN | denotes | activation |
T13197 | 185-188 | NNP | denotes | Akt |
T13196 | 171-184 | JJ | denotes | non-canonical |
T13195 | 167-170 | IN | denotes | for |
T13194 | 158-166 | VBN | denotes | required |
T13193 | 152-157 | RB | denotes | still |
T13192 | 149-151 | VBZ | denotes | is |
T13191 | 140-148 | NN | denotes | activity |
T13157 | 26-28 | IN | denotes | of |
T13156 | 16-25 | NN | denotes | knockdown |
T13155 | 10-15 | NNP | denotes | siRNA |
T13154 | 8-9 | , | denotes | , |
T13153 | 0-8 | RB | denotes | Likewise |
T13190 | 135-139 | NNP | denotes | PDK1 |
T13189 | 131-134 | CC | denotes | and |
T13188 | 126-130 | NNP | denotes | PI3K |
T13187 | 124-125 | , | denotes | , |
T13186 | 115-124 | RB | denotes | Therefore |
T13185 | 113-114 | -RRB- | denotes | ) |
T13184 | 112-113 | NN | denotes | F |
T13183 | 111-112 | , | denotes | , |
T13182 | 108-111 | CD | denotes | S7E |
T13181 | 106-107 | . | denotes | . |
T13180 | 103-106 | NNP | denotes | Fig |
T13179 | 102-103 | -LRB- | denotes | ( |
T13178 | 86-101 | NN | denotes | phosphorylation |
T13177 | 79-85 | NNP | denotes | Thr308 |
T13176 | 75-78 | NNP | denotes | Akt |
T13175 | 65-74 | VBD | denotes | inhibited |
T13174 | 61-64 | CC | denotes | and |
T13173 | 55-60 | NN | denotes | death |
T13172 | 50-54 | IN | denotes | from |
T13171 | 44-49 | NNS | denotes | cells |
T13170 | 34-43 | JJ | denotes | protected |
T13169 | 29-33 | CD | denotes | PDK1 |
R8747 | T13153 | T13175 | advmod | Likewise,inhibited |
R8748 | T13154 | T13175 | punct | ",",inhibited |
R8749 | T13155 | T13156 | compound | siRNA,knockdown |
R8750 | T13156 | T13175 | nsubj | knockdown,inhibited |
R8751 | T13157 | T13156 | prep | of,knockdown |
R8756 | T13169 | T13171 | nummod | PDK1,cells |
R8757 | T13170 | T13171 | amod | protected,cells |
R8758 | T13171 | T13157 | pobj | cells,of |
R8759 | T13172 | T13156 | prep | from,knockdown |
R8760 | T13173 | T13172 | pobj | death,from |
R8761 | T13174 | T13156 | cc | and,knockdown |
R8762 | T13175 | T13175 | ROOT | inhibited,inhibited |
R8763 | T13176 | T13178 | compound | Akt,phosphorylation |
R8764 | T13177 | T13178 | compound | Thr308,phosphorylation |
R8765 | T13178 | T13175 | dobj | phosphorylation,inhibited |
R8766 | T13179 | T13180 | punct | (,Fig |
R8767 | T13180 | T13178 | appos | Fig,phosphorylation |
R8768 | T13181 | T13175 | punct | .,inhibited |
R8769 | T13182 | T13182 | ROOT | S7E,S7E |
R8770 | T13183 | T13184 | punct | ",",F |
R8771 | T13184 | T13182 | appos | F,S7E |
R8772 | T13185 | T13182 | punct | ),S7E |
R8773 | T13186 | T13194 | advmod | Therefore,required |
R8774 | T13187 | T13194 | punct | ",",required |
R8775 | T13188 | T13194 | nsubjpass | PI3K,required |
R8776 | T13189 | T13188 | cc | and,PI3K |
R8777 | T13190 | T13191 | compound | PDK1,activity |
R8778 | T13191 | T13188 | conj | activity,PI3K |
R8779 | T13192 | T13194 | auxpass | is,required |
R8780 | T13193 | T13194 | advmod | still,required |
R8781 | T13194 | T13194 | ROOT | required,required |
R8782 | T13195 | T13194 | prep | for,required |
R8783 | T13196 | T13198 | amod | non-canonical,activation |
R8784 | T13197 | T13198 | compound | Akt,activation |
R8785 | T13198 | T13195 | pobj | activation,for |
R8786 | T13199 | T13194 | prep | during,required |
R8787 | T13200 | T13199 | pobj | necroptosis,during |
R8788 | T13201 | T13194 | punct | .,required |
bionlp-st-ge-2016-test-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13311 | 65-74 | Negative_regulation | denotes | inhibited |
T13310 | 158-166 | Positive_regulation | denotes | required |
T13309 | 158-166 | Positive_regulation | denotes | required |
T13308 | 86-101 | Phosphorylation | denotes | phosphorylation |
T13307 | 16-25 | Negative_regulation | denotes | knockdown |
T13306 | 135-139 | Protein | denotes | PDK1 |
T13305 | 126-130 | Protein | denotes | PI3K |
T13304 | 75-85 | Protein | denotes | Akt Thr308 |
T13303 | 29-33 | Protein | denotes | PDK1 |
R8829 | T13303 | T13307 | themeOf | PDK1,knockdown |
R8830 | T13304 | T13308 | themeOf | Akt Thr308,phosphorylation |
R8831 | T13305 | T13309 | themeOf | PI3K,required |
R8832 | T13306 | T13310 | themeOf | PDK1,required |
R8833 | T13307 | T13309 | causeOf | knockdown,required |
R8834 | T13307 | T13310 | causeOf | knockdown,required |
R8835 | T13307 | T13311 | causeOf | knockdown,inhibited |
R8836 | T13308 | T13311 | themeOf | phosphorylation,inhibited |
test3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12746 | 189-199 | Positive_regulation | denotes | activation |
T12745 | 135-139 | Protein | denotes | PDK1 |
T12744 | 86-101 | Phosphorylation | denotes | phosphorylation |
T12743 | 65-74 | Negative_regulation | denotes | inhibited |
T12742 | 29-33 | Protein | denotes | PDK1 |
T12723 | 135-139 | Protein | denotes | PDK1 |
T12722 | 29-33 | Protein | denotes | PDK1 |
R8416 | T12744 | T12743 | themeOf | phosphorylation,inhibited |