PMC:3585731 / 25094-25597
Annnotations
testone
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8963 | 476-484 | Positive_regulation | denotes | increase |
T8962 | 353-363 | Positive_regulation | denotes | stimulated |
T8961 | 286-292 | Regulation | denotes | effect |
T8960 | 268-278 | Negative_regulation | denotes | inhibitors |
T8959 | 185-192 | Negative_regulation | denotes | reduced |
T8958 | 159-168 | Negative_regulation | denotes | knockdown |
T8957 | 153-158 | Negative_regulation | denotes | siRNA |
T8956 | 70-82 | Positive_regulation | denotes | upregulation |
T8955 | 52-62 | Positive_regulation | denotes | contribute |
T8924 | 488-492 | Protein | denotes | TNFα |
T8923 | 369-373 | Protein | denotes | bFGF |
T8922 | 310-314 | Protein | denotes | TNFα |
T8921 | 255-259 | Protein | denotes | RIP1 |
T8920 | 193-197 | Protein | denotes | TNFα |
T8919 | 86-90 | Protein | denotes | TNFα |
R5812 | T8919 | T8956 | themeOf | TNFα,upregulation |
R5813 | T8921 | T8960 | themeOf | RIP1,inhibitors |
R5814 | T8923 | T8962 | themeOf | bFGF,stimulated |
R5824 | T8956 | T8955 | themeOf | upregulation,contribute |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10143 | 493-502 | NN | denotes | synthesis |
T10142 | 488-492 | NN | denotes | TNFα |
T10141 | 485-487 | IN | denotes | in |
T10140 | 476-484 | NN | denotes | increase |
T10139 | 454-475 | JJ | denotes | necroptosis-dependent |
T10138 | 446-453 | VB | denotes | mediate |
T10137 | 433-445 | RB | denotes | specifically |
T10136 | 425-432 | NN | denotes | kinases |
T10135 | 419-424 | DT | denotes | these |
T10134 | 414-418 | IN | denotes | that |
T10133 | 403-413 | VB | denotes | suggesting |
T10132 | 401-402 | -COMMA- | denotes | , |
T10131 | 400-401 | -RRB- | denotes | ) |
T10130 | 397-400 | NN | denotes | S6C |
T10129 | 392-396 | NNP | denotes | Fig. |
T10128 | 390-391 | -COMMA- | denotes | , |
T10127 | 389-390 | NN | denotes | B |
T10126 | 388-389 | -COMMA- | denotes | , |
T10125 | 386-388 | NN | denotes | 6A |
T10124 | 381-385 | NNP | denotes | Fig. |
T10123 | 380-381 | -LRB- | denotes | ( |
T10122 | 374-379 | RB | denotes | alone |
T10121 | 369-373 | NN | denotes | bFGF |
T10120 | 364-368 | IN | denotes | with |
T10119 | 353-363 | VB | denotes | stimulated |
T10118 | 347-352 | NN | denotes | cells |
T10117 | 343-346 | DT | denotes | the |
T10116 | 340-342 | IN | denotes | in |
T10115 | 337-339 | CC | denotes | or |
T10114 | 331-336 | NN | denotes | cells |
T10113 | 323-330 | NN | denotes | control |
T10112 | 320-322 | IN | denotes | in |
T10111 | 315-319 | NN | denotes | mRNA |
T10110 | 310-314 | NN | denotes | TNFα |
T10109 | 307-309 | IN | denotes | of |
T10108 | 300-306 | NN | denotes | levels |
T10107 | 296-299 | DT | denotes | the |
T10106 | 293-295 | IN | denotes | on |
T10105 | 286-292 | NN | denotes | effect |
T10104 | 283-285 | DT | denotes | no |
T10103 | 279-282 | VB | denotes | had |
T10102 | 268-278 | NN | denotes | inhibitors |
T10101 | 264-267 | NN | denotes | Akt |
T10100 | 260-263 | CC | denotes | and |
T10099 | 255-259 | NN | denotes | RIP1 |
T10098 | 253-254 | -COMMA- | denotes | , |
T10097 | 246-253 | RB | denotes | Notably |
T10096 | 243-244 | -RRB- | denotes | ) |
T10095 | 242-243 | NN | denotes | D |
T10094 | 241-242 | -COMMA- | denotes | , |
T10093 | 240-241 | NN | denotes | C |
T10092 | 239-240 | -COMMA- | denotes | , |
T10091 | 237-239 | NN | denotes | 6B |
T10090 | 232-236 | NN | denotes | Fig. |
T10089 | 231-232 | -LRB- | denotes | ( |
T10088 | 225-230 | NN | denotes | cells |
T10087 | 213-224 | JJ | denotes | necroptotic |
T10086 | 210-212 | IN | denotes | in |
T10085 | 203-209 | NN | denotes | levels |
T10084 | 198-202 | NN | denotes | mRNA |
T10083 | 193-197 | NN | denotes | TNFα |
T10082 | 185-192 | VB | denotes | reduced |
T10081 | 180-184 | NN | denotes | mTOR |
T10080 | 176-179 | CC | denotes | and |
T10079 | 172-175 | NN | denotes | Akt |
T10078 | 169-171 | IN | denotes | of |
T10077 | 159-168 | NN | denotes | knockdown |
T10076 | 153-158 | NN | denotes | siRNA |
T10075 | 149-152 | CC | denotes | and |
T10074 | 138-148 | NN | denotes | inhibition |
T10073 | 123-137 | JJ | denotes | small-molecule |
T10072 | 118-122 | DT | denotes | both |
T10071 | 115-117 | IN | denotes | as |
T10070 | 103-114 | NN | denotes | necroptosis |
T10069 | 96-102 | IN | denotes | during |
T10068 | 91-95 | NN | denotes | mRNA |
T10067 | 86-90 | NN | denotes | TNFα |
T10066 | 83-85 | IN | denotes | of |
T10065 | 70-82 | NN | denotes | upregulation |
T10064 | 66-69 | DT | denotes | the |
T10063 | 63-65 | TO | denotes | to |
T10062 | 52-62 | VB | denotes | contribute |
T10061 | 45-51 | NN | denotes | mTORC1 |
T10060 | 41-44 | CC | denotes | and |
T10059 | 37-40 | NN | denotes | Akt |
T10058 | 32-36 | CC | denotes | both |
T10057 | 27-31 | IN | denotes | that |
T10056 | 17-26 | VB | denotes | suggested |
T10055 | 8-16 | NN | denotes | analysis |
T10054 | 0-7 | JJ | denotes | Further |
R6568 | T10055 | T10054 | arg1Of | analysis,Further |
R6569 | T10055 | T10056 | arg1Of | analysis,suggested |
R6570 | T10059 | T10060 | arg1Of | Akt,and |
R6571 | T10060 | T10058 | arg1Of | and,both |
R6572 | T10060 | T10062 | arg1Of | and,contribute |
R6573 | T10061 | T10060 | arg2Of | mTORC1,and |
R6574 | T10062 | T10056 | arg2Of | contribute,suggested |
R6575 | T10062 | T10057 | arg1Of | contribute,that |
R6576 | T10062 | T10063 | arg1Of | contribute,to |
R6577 | T10062 | T10069 | arg1Of | contribute,during |
R6578 | T10062 | T10071 | arg1Of | contribute,as |
R6579 | T10065 | T10063 | arg2Of | upregulation,to |
R6580 | T10065 | T10064 | arg1Of | upregulation,the |
R6581 | T10065 | T10066 | arg1Of | upregulation,of |
R6582 | T10068 | T10066 | arg2Of | mRNA,of |
R6583 | T10068 | T10067 | arg1Of | mRNA,TNFα |
R6584 | T10070 | T10069 | arg2Of | necroptosis,during |
R6585 | T10074 | T10072 | arg1Of | inhibition,both |
R6586 | T10074 | T10073 | arg1Of | inhibition,small-molecule |
R6587 | T10074 | T10075 | arg1Of | inhibition,and |
R6588 | T10075 | T10082 | arg1Of | and,reduced |
R6589 | T10077 | T10075 | arg2Of | knockdown,and |
R6590 | T10077 | T10076 | arg1Of | knockdown,siRNA |
R6591 | T10077 | T10078 | arg1Of | knockdown,of |
R6592 | T10079 | T10080 | arg1Of | Akt,and |
R6593 | T10080 | T10078 | arg2Of | and,of |
R6594 | T10081 | T10080 | arg2Of | mTOR,and |
R6595 | T10082 | T10071 | arg2Of | reduced,as |
R6596 | T10085 | T10082 | arg2Of | levels,reduced |
R6597 | T10085 | T10083 | arg1Of | levels,TNFα |
R6598 | T10085 | T10084 | arg1Of | levels,mRNA |
R6599 | T10085 | T10086 | arg1Of | levels,in |
R6600 | T10085 | T10089 | arg1Of | levels,( |
R6601 | T10088 | T10086 | arg2Of | cells,in |
R6602 | T10088 | T10087 | arg1Of | cells,necroptotic |
R6603 | T10091 | T10089 | arg2Of | 6B,( |
R6604 | T10091 | T10090 | arg1Of | 6B,Fig. |
R6605 | T10091 | T10092 | arg1Of | 6B,"," |
R6606 | T10091 | T10094 | arg1Of | 6B,"," |
R6607 | T10093 | T10092 | arg2Of | C,"," |
R6608 | T10095 | T10094 | arg2Of | D,"," |
R6609 | T10096 | T10089 | arg3Of | ),( |
R6610 | T10099 | T10100 | arg1Of | RIP1,and |
R6611 | T10101 | T10100 | arg2Of | Akt,and |
R6612 | T10102 | T10099 | arg1Of | inhibitors,RIP1 |
R6613 | T10102 | T10101 | arg1Of | inhibitors,Akt |
R6614 | T10102 | T10103 | arg1Of | inhibitors,had |
R6615 | T10103 | T10097 | arg1Of | had,Notably |
R6616 | T10103 | T10098 | arg1Of | had,"," |
R6617 | T10103 | T10106 | arg1Of | had,on |
R6618 | T10103 | T10132 | arg1Of | had,"," |
R6619 | T10103 | T10133 | modOf | had,suggesting |
R6620 | T10105 | T10103 | arg2Of | effect,had |
R6621 | T10105 | T10104 | arg1Of | effect,no |
R6622 | T10108 | T10106 | arg2Of | levels,on |
R6623 | T10108 | T10107 | arg1Of | levels,the |
R6624 | T10108 | T10109 | arg1Of | levels,of |
R6625 | T10108 | T10112 | arg1Of | levels,in |
R6626 | T10108 | T10116 | arg1Of | levels,in |
R6627 | T10108 | T10123 | arg1Of | levels,( |
R6628 | T10111 | T10109 | arg2Of | mRNA,of |
R6629 | T10111 | T10110 | arg1Of | mRNA,TNFα |
R6630 | T10112 | T10115 | arg1Of | in,or |
R6631 | T10114 | T10112 | arg2Of | cells,in |
R6632 | T10114 | T10113 | arg1Of | cells,control |
R6633 | T10116 | T10115 | arg2Of | in,or |
R6634 | T10118 | T10116 | arg2Of | cells,in |
R6635 | T10118 | T10117 | arg1Of | cells,the |
R6636 | T10118 | T10119 | arg2Of | cells,stimulated |
R6637 | T10119 | T10120 | arg1Of | stimulated,with |
R6638 | T10121 | T10120 | arg2Of | bFGF,with |
R6639 | T10121 | T10122 | arg1Of | bFGF,alone |
R6640 | T10125 | T10123 | arg2Of | 6A,( |
R6641 | T10125 | T10124 | arg1Of | 6A,Fig. |
R6642 | T10125 | T10126 | arg1Of | 6A,"," |
R6643 | T10125 | T10128 | arg1Of | 6A,"," |
R6644 | T10127 | T10126 | arg2Of | B,"," |
R6645 | T10130 | T10128 | arg2Of | S6C,"," |
R6646 | T10130 | T10129 | arg1Of | S6C,Fig. |
R6647 | T10131 | T10123 | arg3Of | ),( |
R6648 | T10136 | T10135 | arg1Of | kinases,these |
R6649 | T10136 | T10138 | arg1Of | kinases,mediate |
R6650 | T10138 | T10133 | arg2Of | mediate,suggesting |
R6651 | T10138 | T10134 | arg1Of | mediate,that |
R6652 | T10138 | T10137 | arg1Of | mediate,specifically |
R6653 | T10140 | T10138 | arg2Of | increase,mediate |
R6654 | T10140 | T10139 | arg1Of | increase,necroptosis-dependent |
R6655 | T10140 | T10141 | arg1Of | increase,in |
R6656 | T10143 | T10141 | arg2Of | synthesis,in |
R6657 | T10143 | T10142 | arg1Of | synthesis,TNFα |
bionlp-st-ge-2016-coref
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9197 | 255-259 | Antecedent | denotes | RIP1 |
T9196 | 419-432 | Anaphor | denotes | these kinases |
R5908 | T9196 | T9197 | boundBy | these kinases,RIP1 |
bionlp-st-ge-2016-test-proteins
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9239 | 488-492 | Protein | denotes | TNFα |
T9238 | 369-373 | Protein | denotes | bFGF |
T9237 | 310-314 | Protein | denotes | TNFα |
T9236 | 255-259 | Protein | denotes | RIP1 |
T9235 | 193-197 | Protein | denotes | TNFα |
T9234 | 86-90 | Protein | denotes | TNFα |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10314 | 369-373 | http://www.uniprot.org/uniprot/Q788Q8 | denotes | bFGF |
T10312 | 488-492 | http://www.uniprot.org/uniprot/P01375 | denotes | TNFα |
T10311 | 310-314 | http://www.uniprot.org/uniprot/P01375 | denotes | TNFα |
T10310 | 193-197 | http://www.uniprot.org/uniprot/P01375 | denotes | TNFα |
T10309 | 86-90 | http://www.uniprot.org/uniprot/P01375 | denotes | TNFα |
T10273 | 172-175 | http://www.uniprot.org/uniprot/P31751 | denotes | Akt |
T10272 | 37-40 | http://www.uniprot.org/uniprot/P31751 | denotes | Akt |
T10260 | 264-267 | http://www.uniprot.org/uniprot/P31749 | denotes | Akt |
T10259 | 172-175 | http://www.uniprot.org/uniprot/P31749 | denotes | Akt |
T10258 | 37-40 | http://www.uniprot.org/uniprot/P31749 | denotes | Akt |
T10293 | 255-259 | http://www.uniprot.org/uniprot/Q13546 | denotes | RIP1 |
T10288 | 264-267 | http://www.uniprot.org/uniprot/Q9Y243 | denotes | Akt |
T10287 | 172-175 | http://www.uniprot.org/uniprot/Q9Y243 | denotes | Akt |
T10286 | 37-40 | http://www.uniprot.org/uniprot/Q9Y243 | denotes | Akt |
T10274 | 264-267 | http://www.uniprot.org/uniprot/P31751 | denotes | Akt |
T10299 | 180-184 | http://www.uniprot.org/uniprot/P42345 | denotes | mTOR |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9312 | 493-502 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
T9282 | 454-465 | http://purl.obolibrary.org/obo/GO_0097528 | denotes | necroptosis |
T9281 | 103-114 | http://purl.obolibrary.org/obo/GO_0097528 | denotes | necroptosis |
T9260 | 103-114 | http://purl.obolibrary.org/obo/GO_0070266 | denotes | necroptosis |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9332 | 45-51 | http://purl.obolibrary.org/obo/GO_0031931 | denotes | mTORC1 |
T9327 | 347-352 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T9326 | 331-336 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T9325 | 225-230 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9111 | 246-503 | Sentence | denotes | Notably, RIP1 and Akt inhibitors had no effect on the levels of TNFα mRNA in control cells or in the cells stimulated with bFGF alone (Fig. 6A,B, Fig. S6C), suggesting that these kinases specifically mediate necroptosis-dependent increase in TNFα synthesis. |
T9110 | 0-245 | Sentence | denotes | Further analysis suggested that both Akt and mTORC1 contribute to the upregulation of TNFα mRNA during necroptosis as both small-molecule inhibition and siRNA knockdown of Akt and mTOR reduced TNFα mRNA levels in necroptotic cells (Fig. 6B,C,D). |
T161 | 0-245 | Sentence | denotes | Further analysis suggested that both Akt and mTORC1 contribute to the upregulation of TNFα mRNA during necroptosis as both small-molecule inhibition and siRNA knockdown of Akt and mTOR reduced TNFα mRNA levels in necroptotic cells (Fig. 6B,C,D). |
T162 | 246-503 | Sentence | denotes | Notably, RIP1 and Akt inhibitors had no effect on the levels of TNFα mRNA in control cells or in the cells stimulated with bFGF alone (Fig. 6A,B, Fig. S6C), suggesting that these kinases specifically mediate necroptosis-dependent increase in TNFα synthesis. |
simple1
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9375 | 488-492 | Protein | denotes | TNFα |
T9374 | 369-373 | Protein | denotes | bFGF |
T9373 | 310-314 | Protein | denotes | TNFα |
T9372 | 255-259 | Protein | denotes | RIP1 |
T9371 | 193-197 | Protein | denotes | TNFα |
T9370 | 86-90 | Protein | denotes | TNFα |
BioNLP16_DUT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10238 | 52-62 | Positive_regulation | denotes | contribute |
T10213 | 488-492 | Protein | denotes | TNFα |
T10212 | 369-373 | Protein | denotes | bFGF |
T10211 | 310-314 | Protein | denotes | TNFα |
T10210 | 255-259 | Protein | denotes | RIP1 |
T10209 | 193-197 | Protein | denotes | TNFα |
T10208 | 86-90 | Protein | denotes | TNFα |
T10246 | 476-484 | Positive_regulation | denotes | increase |
T10245 | 493-502 | Gene_expression | denotes | synthesis |
T10244 | 268-278 | Negative_regulation | denotes | inhibitors |
T10243 | 446-453 | Positive_regulation | denotes | mediate |
T10242 | 286-292 | Regulation | denotes | effect |
T10241 | 203-209 | Transcription | denotes | levels |
T10240 | 70-82 | Positive_regulation | denotes | upregulation |
T10239 | 185-192 | Negative_regulation | denotes | reduced |
R6681 | T10208 | T10240 | themeOf | TNFα,upregulation |
R6682 | T10209 | T10239 | themeOf | TNFα,reduced |
R6683 | T10209 | T10241 | themeOf | TNFα,levels |
R6684 | T10210 | T10244 | themeOf | RIP1,inhibitors |
R6685 | T10211 | T10242 | themeOf | TNFα,effect |
R6686 | T10213 | T10245 | themeOf | TNFα,synthesis |
R6698 | T10240 | T10238 | themeOf | upregulation,contribute |
R6699 | T10245 | T10246 | themeOf | synthesis,increase |
R6700 | T10246 | T10243 | themeOf | increase,mediate |
BioNLP16_Messiy
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10530 | 476-484 | Positive_regulation | denotes | increase |
T10529 | 268-278 | Negative_regulation | denotes | inhibitors |
T10528 | 286-292 | Regulation | denotes | effect |
T10527 | 493-502 | Gene_expression | denotes | synthesis |
T10526 | 70-82 | Positive_regulation | denotes | upregulation |
T10525 | 185-192 | Negative_regulation | denotes | reduced |
T10524 | 52-62 | Positive_regulation | denotes | contribute |
T10500 | 488-492 | Protein | denotes | TNFα |
T10499 | 369-373 | Protein | denotes | bFGF |
T10498 | 310-314 | Protein | denotes | TNFα |
T10497 | 255-259 | Protein | denotes | RIP1 |
T10496 | 193-197 | Protein | denotes | TNFα |
T10495 | 86-90 | Protein | denotes | TNFα |
R6797 | T10495 | T10526 | themeOf | TNFα,upregulation |
R6798 | T10496 | T10525 | themeOf | TNFα,reduced |
R6799 | T10497 | T10529 | themeOf | RIP1,inhibitors |
R6800 | T10498 | T10528 | themeOf | TNFα,effect |
R6801 | T10500 | T10527 | themeOf | TNFα,synthesis |
R6814 | T10526 | T10524 | themeOf | upregulation,contribute |
R6815 | T10527 | T10530 | themeOf | synthesis,increase |
DLUT931
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10397 | 454-475 | Regulation | denotes | necroptosis-dependent |
T10396 | 446-453 | Positive_regulation | denotes | mediate |
T10395 | 476-484 | Positive_regulation | denotes | increase |
T10394 | 286-292 | Regulation | denotes | effect |
T10393 | 493-502 | Gene_expression | denotes | synthesis |
T10392 | 353-363 | Positive_regulation | denotes | stimulated |
T10353 | 255-259 | Protein | denotes | RIP1 |
T10352 | 193-197 | Protein | denotes | TNFα |
T10351 | 86-90 | Protein | denotes | TNFα |
T10356 | 488-492 | Protein | denotes | TNFα |
T10391 | 315-319 | Transcription | denotes | mRNA |
T10390 | 268-278 | Negative_regulation | denotes | inhibitors |
T10389 | 52-62 | Positive_regulation | denotes | contribute |
T10388 | 203-209 | Transcription | denotes | levels |
T10387 | 70-82 | Positive_regulation | denotes | upregulation |
T10355 | 369-373 | Protein | denotes | bFGF |
T10354 | 310-314 | Protein | denotes | TNFα |
R6730 | T10351 | T10387 | themeOf | TNFα,upregulation |
R6731 | T10352 | T10388 | themeOf | TNFα,levels |
R6732 | T10353 | T10390 | themeOf | RIP1,inhibitors |
R6733 | T10354 | T10391 | themeOf | TNFα,mRNA |
R6734 | T10355 | T10392 | themeOf | bFGF,stimulated |
R6735 | T10356 | T10393 | themeOf | TNFα,synthesis |
R6753 | T10387 | T10389 | themeOf | upregulation,contribute |
R6754 | T10390 | T10394 | causeOf | inhibitors,effect |
R6755 | T10391 | T10394 | themeOf | mRNA,effect |
R6756 | T10393 | T10395 | themeOf | synthesis,increase |
R6757 | T10395 | T10396 | themeOf | increase,mediate |
R6758 | T10395 | T10397 | themeOf | increase,necroptosis-dependent |
bionlp-st-ge-2016-test-ihmc
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10938 | 414-502 | Regulation | denotes | that these kinases specifically mediate necroptosis-dependent increase in TNFα synthesis |
T10936 | 454-502 | Regulation | denotes | necroptosis-dependent increase in TNFα synthesis |
T10934 | 66-114 | Positive_regulation | denotes | the upregulation of TNFα mRNA during necroptosis |
T10913 | 381-384 | Protein | denotes | Fig |
T10912 | 172-175 | Protein | denotes | Akt |
T10900 | 485-502 | Protein | denotes | in TNFα synthesis |
T10891 | 323-336 | Entity | denotes | control cells |
T10890 | 369-373 | Protein | denotes | bFGF |
T10885 | 419-432 | Protein | denotes | these kinases |
T10873 | 310-314 | Protein | denotes | TNFα |
T10872 | 180-184 | Protein | denotes | mTOR |
T10869 | 343-363 | Entity | denotes | the cells stimulated |
T10864 | 255-259 | Protein | denotes | RIP1 |
T10858 | 86-90 | Protein | denotes | TNFα |
T10851 | 193-209 | Protein | denotes | TNFα mRNA levels |
T10849 | 264-267 | Protein | denotes | Akt |
T10846 | 37-40 | Protein | denotes | Akt |
T10843 | 232-235 | Protein | denotes | Fig |
T10842 | 83-95 | Protein | denotes | of TNFα mRNA |
T10832 | 193-197 | Protein | denotes | TNFα |
T10819 | 213-230 | Entity | denotes | necroptotic cells |
T10809 | 264-278 | Entity | denotes | Akt inhibitors |
T10806 | 123-137 | Entity | denotes | small-molecule |
T10801 | 307-319 | Protein | denotes | of TNFα mRNA |
T10800 | 392-395 | Protein | denotes | Fig |
T10793 | 46-51 | Entity | denotes | TORC1 |
R6966 | T10842 | T10934 | themeOf | of TNFα mRNA,the upregulation of TNFα mRNA during necroptosis |
R6971 | T10885 | T10938 | causeOf | these kinases,that these kinases specifically mediate necroptosis-dependent increase in TNFα synthesis |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11727 | 502-503 | . | denotes | . |
T11726 | 493-502 | NN | denotes | synthesis |
T11725 | 488-492 | NNP | denotes | TNFα |
T11724 | 485-487 | IN | denotes | in |
T11723 | 476-484 | NN | denotes | increase |
T11722 | 454-475 | JJ | denotes | necroptosis-dependent |
T11721 | 446-453 | VBP | denotes | mediate |
T11720 | 433-445 | RB | denotes | specifically |
T11719 | 425-432 | NNS | denotes | kinases |
T11718 | 419-424 | DT | denotes | these |
T11717 | 414-418 | IN | denotes | that |
T11716 | 403-413 | VBG | denotes | suggesting |
T11715 | 401-402 | , | denotes | , |
T11714 | 400-401 | -RRB- | denotes | ) |
T11713 | 397-400 | CD | denotes | S6C |
T11712 | 395-396 | . | denotes | . |
T11711 | 392-395 | NNP | denotes | Fig |
T11710 | 390-391 | , | denotes | , |
T11709 | 389-390 | NNP | denotes | B |
T11708 | 388-389 | , | denotes | , |
T11707 | 386-388 | NNP | denotes | 6A |
T11706 | 381-385 | NNP | denotes | Fig. |
T11705 | 380-381 | -LRB- | denotes | ( |
T11704 | 374-379 | RB | denotes | alone |
T11703 | 369-373 | NNP | denotes | bFGF |
T11702 | 364-368 | IN | denotes | with |
T11701 | 353-363 | VBN | denotes | stimulated |
T11700 | 347-352 | NNS | denotes | cells |
T11699 | 343-346 | DT | denotes | the |
T11698 | 340-342 | IN | denotes | in |
T11697 | 337-339 | CC | denotes | or |
T11696 | 331-336 | NNS | denotes | cells |
T11695 | 323-330 | NN | denotes | control |
T11694 | 320-322 | IN | denotes | in |
T11693 | 315-319 | NNP | denotes | mRNA |
T11692 | 310-314 | NNP | denotes | TNFα |
T11691 | 307-309 | IN | denotes | of |
T11690 | 300-306 | NNS | denotes | levels |
T11689 | 296-299 | DT | denotes | the |
T11688 | 293-295 | IN | denotes | on |
T11687 | 286-292 | NN | denotes | effect |
T11686 | 283-285 | DT | denotes | no |
T11685 | 279-282 | VBD | denotes | had |
T11684 | 268-278 | NNS | denotes | inhibitors |
T11683 | 264-267 | NNP | denotes | Akt |
T11682 | 260-263 | CC | denotes | and |
T11681 | 255-259 | NNP | denotes | RIP1 |
T11680 | 253-254 | , | denotes | , |
T11679 | 246-253 | RB | denotes | Notably |
T11678 | 244-245 | . | denotes | . |
T11677 | 243-244 | -RRB- | denotes | ) |
T11676 | 242-243 | NNP | denotes | D |
T11675 | 241-242 | , | denotes | , |
T11674 | 240-241 | NNP | denotes | C |
T11673 | 239-240 | , | denotes | , |
T11672 | 237-239 | NNP | denotes | 6B |
T11671 | 232-236 | NNP | denotes | Fig. |
T11670 | 231-232 | -LRB- | denotes | ( |
T11669 | 225-230 | NNS | denotes | cells |
T11668 | 213-224 | JJ | denotes | necroptotic |
T11667 | 210-212 | IN | denotes | in |
T11666 | 203-209 | NNS | denotes | levels |
T11665 | 198-202 | NNP | denotes | mRNA |
T11664 | 193-197 | NNP | denotes | TNFα |
T11663 | 185-192 | VBD | denotes | reduced |
T11662 | 180-184 | NNP | denotes | mTOR |
T11661 | 176-179 | CC | denotes | and |
T11660 | 172-175 | NNP | denotes | Akt |
T11659 | 169-171 | IN | denotes | of |
T11658 | 159-168 | NN | denotes | knockdown |
T11657 | 153-158 | NN | denotes | siRNA |
T11656 | 149-152 | CC | denotes | and |
T11655 | 138-148 | NN | denotes | inhibition |
T11654 | 123-137 | JJ | denotes | small-molecule |
T11653 | 118-122 | DT | denotes | both |
T11652 | 115-117 | IN | denotes | as |
T11651 | 103-114 | NN | denotes | necroptosis |
T11650 | 96-102 | IN | denotes | during |
T11639 | 32-36 | DT | denotes | both |
T11638 | 27-31 | IN | denotes | that |
T11637 | 17-26 | VBD | denotes | suggested |
T11636 | 8-16 | NN | denotes | analysis |
T11635 | 0-7 | JJ | denotes | Further |
T11649 | 91-95 | NNP | denotes | mRNA |
T11648 | 86-90 | NNP | denotes | TNFα |
T11647 | 83-85 | IN | denotes | of |
T11646 | 70-82 | NN | denotes | upregulation |
T11645 | 66-69 | DT | denotes | the |
T11644 | 63-65 | TO | denotes | to |
T11643 | 52-62 | VBP | denotes | contribute |
T11642 | 45-51 | NNP | denotes | mTORC1 |
T11641 | 41-44 | CC | denotes | and |
T11640 | 37-40 | NNP | denotes | Akt |
R7629 | T11640 | T11643 | nsubj | Akt,contribute |
R7633 | T11641 | T11640 | cc | and,Akt |
R7637 | T11642 | T11640 | conj | mTORC1,Akt |
R7640 | T11643 | T11637 | ccomp | contribute,suggested |
R7644 | T11644 | T11643 | prep | to,contribute |
R7648 | T11645 | T11646 | det | the,upregulation |
R7652 | T11646 | T11644 | pobj | upregulation,to |
R7657 | T11647 | T11646 | prep | of,upregulation |
R7660 | T11648 | T11649 | compound | TNFα,mRNA |
R7664 | T11649 | T11647 | pobj | mRNA,of |
R7671 | T11650 | T11643 | prep | during,contribute |
R7675 | T11651 | T11650 | pobj | necroptosis,during |
R7678 | T11652 | T11663 | mark | as,reduced |
R7682 | T11653 | T11655 | det | both,inhibition |
R7686 | T11654 | T11655 | amod | small-molecule,inhibition |
R7687 | T11635 | T11636 | amod | Further,analysis |
R7688 | T11636 | T11637 | nsubj | analysis,suggested |
R7689 | T11637 | T11637 | ROOT | suggested,suggested |
R7690 | T11655 | T11652 | pobj | inhibition,as |
R7691 | T11638 | T11643 | mark | that,contribute |
R7692 | T11639 | T11640 | preconj | both,Akt |
R7693 | T11656 | T11655 | cc | and,inhibition |
R7694 | T11657 | T11655 | conj | siRNA,inhibition |
R7696 | T11659 | T11658 | prep | of,knockdown |
R7697 | T11660 | T11659 | pobj | Akt,of |
R7698 | T11661 | T11660 | cc | and,Akt |
R7699 | T11662 | T11660 | conj | mTOR,Akt |
R7700 | T11663 | T11643 | advcl | reduced,contribute |
R7701 | T11664 | T11665 | compound | TNFα,mRNA |
R7702 | T11665 | T11666 | compound | mRNA,levels |
R7703 | T11666 | T11663 | dobj | levels,reduced |
R7704 | T11667 | T11663 | prep | in,reduced |
R7705 | T11668 | T11669 | amod | necroptotic,cells |
R7706 | T11669 | T11667 | pobj | cells,in |
R7707 | T11670 | T11672 | punct | (,6B |
R7708 | T11671 | T11672 | compound | Fig.,6B |
R7709 | T11672 | T11643 | npadvmod | 6B,contribute |
R7710 | T11673 | T11672 | punct | ",",6B |
R7711 | T11674 | T11672 | conj | C,6B |
R7712 | T11675 | T11674 | punct | ",",C |
R7713 | T11676 | T11674 | conj | D,C |
R7714 | T11677 | T11672 | punct | ),6B |
R7715 | T11678 | T11637 | punct | .,suggested |
R7716 | T11679 | T11685 | advmod | Notably,had |
R7717 | T11680 | T11685 | punct | ",",had |
R7718 | T11681 | T11684 | nmod | RIP1,inhibitors |
R7719 | T11682 | T11681 | cc | and,RIP1 |
R7720 | T11683 | T11681 | conj | Akt,RIP1 |
R7721 | T11684 | T11685 | nsubj | inhibitors,had |
R7722 | T11685 | T11685 | ROOT | had,had |
R7723 | T11686 | T11687 | det | no,effect |
R7724 | T11687 | T11685 | dobj | effect,had |
R7725 | T11688 | T11687 | prep | on,effect |
R7726 | T11689 | T11690 | det | the,levels |
R7727 | T11690 | T11688 | pobj | levels,on |
R7728 | T11691 | T11690 | prep | of,levels |
R7729 | T11692 | T11693 | compound | TNFα,mRNA |
R7730 | T11693 | T11691 | pobj | mRNA,of |
R7731 | T11694 | T11690 | prep | in,levels |
R7732 | T11695 | T11696 | compound | control,cells |
R7733 | T11696 | T11694 | pobj | cells,in |
R7734 | T11697 | T11694 | cc | or,in |
R7735 | T11698 | T11694 | conj | in,in |
R7736 | T11699 | T11700 | det | the,cells |
R7737 | T11700 | T11698 | pobj | cells,in |
R7738 | T11701 | T11700 | acl | stimulated,cells |
R7739 | T11702 | T11701 | prep | with,stimulated |
R7740 | T11703 | T11702 | pobj | bFGF,with |
R7741 | T11704 | T11703 | advmod | alone,bFGF |
R7742 | T11705 | T11707 | punct | (,6A |
R7743 | T11706 | T11707 | compound | Fig.,6A |
R7744 | T11707 | T11703 | appos | 6A,bFGF |
R7745 | T11708 | T11707 | punct | ",",6A |
R7746 | T11709 | T11707 | conj | B,6A |
R7747 | T11710 | T11709 | punct | ",",B |
R7748 | T11711 | T11709 | conj | Fig,B |
R7749 | T11712 | T11685 | punct | .,had |
R7750 | T11713 | T11713 | ROOT | S6C,S6C |
R7751 | T11714 | T11713 | punct | ),S6C |
R7752 | T11715 | T11713 | punct | ",",S6C |
R7753 | T11716 | T11713 | acl | suggesting,S6C |
R7754 | T11717 | T11721 | mark | that,mediate |
R7755 | T11718 | T11719 | det | these,kinases |
R7756 | T11719 | T11721 | nsubj | kinases,mediate |
R7757 | T11720 | T11721 | advmod | specifically,mediate |
R7758 | T11721 | T11716 | ccomp | mediate,suggesting |
R7759 | T11722 | T11723 | amod | necroptosis-dependent,increase |
R7760 | T11723 | T11721 | dobj | increase,mediate |
R7761 | T11724 | T11723 | prep | in,increase |
R7762 | T11725 | T11726 | compound | TNFα,synthesis |
R7763 | T11726 | T11724 | pobj | synthesis,in |
R7764 | T11727 | T11713 | punct | .,S6C |
R7695 | T11658 | T11655 | conj | knockdown,inhibition |
bionlp-st-ge-2016-test-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10661 | 476-484 | Positive_regulation | denotes | increase |
T10660 | 493-502 | Gene_expression | denotes | synthesis |
T10659 | 286-292 | Regulation | denotes | effect |
T10658 | 286-292 | Regulation | denotes | effect |
T10657 | 268-278 | Negative_regulation | denotes | inhibitors |
T10656 | 268-278 | Negative_regulation | denotes | inhibitors |
T10655 | 488-492 | Protein | denotes | TNFα |
T10654 | 369-373 | Protein | denotes | bFGF |
T10653 | 310-319 | Protein | denotes | TNFα mRNA |
T10652 | 264-267 | Protein | denotes | Akt |
T10651 | 255-259 | Protein | denotes | RIP1 |
T10650 | 153-158 | Negative_regulation | denotes | siRNA |
T10649 | 153-158 | Negative_regulation | denotes | siRNA |
T10648 | 138-148 | Negative_regulation | denotes | inhibition |
T10647 | 138-148 | Negative_regulation | denotes | inhibition |
T10646 | 52-62 | Positive_regulation | denotes | contribute |
T10645 | 52-62 | Positive_regulation | denotes | contribute |
T10644 | 203-209 | Positive_regulation | denotes | levels |
T10643 | 159-168 | Negative_regulation | denotes | knockdown |
T10642 | 159-168 | Negative_regulation | denotes | knockdown |
T10641 | 153-158 | Negative_regulation | denotes | siRNA |
T10640 | 70-82 | Positive_regulation | denotes | upregulation |
T10639 | 180-202 | Protein | denotes | mTOR reduced TNFα mRNA |
T10638 | 172-175 | Protein | denotes | Akt |
T10637 | 86-95 | Protein | denotes | TNFα mRNA |
T10636 | 45-51 | Protein | denotes | mTORC1 |
T10635 | 37-40 | Protein | denotes | Akt |
R6869 | T10636 | T10646 | causeOf | mTORC1,contribute |
R6874 | T10640 | T10645 | themeOf | upregulation,contribute |
R6875 | T10640 | T10646 | themeOf | upregulation,contribute |
R6877 | T10642 | T10647 | themeOf | knockdown,inhibition |
R6878 | T10642 | T10649 | themeOf | knockdown,siRNA |
R6879 | T10643 | T10648 | themeOf | knockdown,inhibition |
R6880 | T10643 | T10650 | themeOf | knockdown,siRNA |
R6881 | T10651 | T10656 | themeOf | RIP1,inhibitors |
R6882 | T10652 | T10657 | themeOf | Akt,inhibitors |
R6883 | T10653 | T10658 | themeOf | TNFα mRNA,effect |
R6884 | T10653 | T10659 | themeOf | TNFα mRNA,effect |
R6885 | T10655 | T10660 | themeOf | TNFα,synthesis |
R6886 | T10656 | T10658 | causeOf | inhibitors,effect |
R6887 | T10657 | T10659 | causeOf | inhibitors,effect |
R6888 | T10660 | T10661 | themeOf | synthesis,increase |
R6868 | T10635 | T10645 | causeOf | Akt,contribute |
R6870 | T10637 | T10640 | themeOf | TNFα mRNA,upregulation |
R6871 | T10638 | T10641 | themeOf | Akt,siRNA |
R6872 | T10638 | T10642 | themeOf | Akt,knockdown |
R6873 | T10639 | T10644 | themeOf | mTOR reduced TNFα mRNA,levels |
R6876 | T10641 | T10643 | themeOf | siRNA,knockdown |
test3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9005 | 488-492 | Protein | denotes | TNFα |
T9004 | 369-373 | Protein | denotes | bFGF |
T9003 | 310-314 | Protein | denotes | TNFα |
T9002 | 255-259 | Protein | denotes | RIP1 |
T9001 | 193-197 | Protein | denotes | TNFα |
T9000 | 86-90 | Protein | denotes | TNFα |
T9083 | 493-502 | Gene_expression | denotes | synthesis |
T9082 | 488-492 | Protein | denotes | TNFα |
T9081 | 476-484 | Positive_regulation | denotes | increase |
T9080 | 369-373 | Protein | denotes | bFGF |
T9079 | 310-314 | Protein | denotes | TNFα |
T9078 | 286-292 | Regulation | denotes | effect |
T9077 | 268-278 | Negative_regulation | denotes | inhibitors |
T9076 | 255-259 | Protein | denotes | RIP1 |
T9075 | 193-197 | Protein | denotes | TNFα |
T9074 | 185-192 | Negative_regulation | denotes | reduced |
T9073 | 159-168 | Negative_regulation | denotes | knockdown |
T9072 | 86-90 | Protein | denotes | TNFα |
T9071 | 70-82 | Positive_regulation | denotes | upregulation |
T9070 | 52-62 | Positive_regulation | denotes | contribute |
R5853 | T9071 | T9070 | themeOf | upregulation,contribute |
R5854 | T9072 | T9071 | themeOf | TNFα,upregulation |
R5855 | T9073 | T9074 | causeOf | knockdown,reduced |
R5856 | T9076 | T9077 | themeOf | RIP1,inhibitors |
R5857 | T9077 | T9078 | causeOf | inhibitors,effect |
R5858 | T9080 | T9078 | causeOf | bFGF,effect |
R5859 | T9082 | T9083 | themeOf | TNFα,synthesis |
R5860 | T9083 | T9081 | themeOf | synthesis,increase |