PMC:3585731 / 185-559 JSONTXT

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    testone

    {"project":"testone","denotations":[{"id":"T14","span":{"begin":290,"end":294},"obj":"Protein"},{"id":"T13","span":{"begin":258,"end":288},"obj":"Protein"}],"relations":[{"id":"R1","pred":"equivalentTo","subj":"T14","obj":"T13"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    pmc-enju-pas

    {"project":"pmc-enju-pas","denotations":[{"id":"T226","span":{"begin":368,"end":372},"obj":"NN"},{"id":"T225","span":{"begin":365,"end":367},"obj":"IN"},{"id":"T224","span":{"begin":353,"end":364},"obj":"NN"},{"id":"T223","span":{"begin":349,"end":352},"obj":"IN"},{"id":"T222","span":{"begin":340,"end":348},"obj":"JJ"},{"id":"T221","span":{"begin":337,"end":339},"obj":"VB"},{"id":"T220","span":{"begin":328,"end":336},"obj":"NN"},{"id":"T219","span":{"begin":321,"end":327},"obj":"NN"},{"id":"T218","span":{"begin":317,"end":320},"obj":"NN"},{"id":"T217","span":{"begin":312,"end":316},"obj":"IN"},{"id":"T216","span":{"begin":307,"end":311},"obj":"VB"},{"id":"T215","span":{"begin":304,"end":306},"obj":"PRP"},{"id":"T214","span":{"begin":296,"end":302},"obj":"NN"},{"id":"T213","span":{"begin":294,"end":295},"obj":"-RRB-"},{"id":"T212","span":{"begin":290,"end":294},"obj":"NN"},{"id":"T211","span":{"begin":289,"end":290},"obj":"-LRB-"},{"id":"T210","span":{"begin":279,"end":288},"obj":"NN"},{"id":"T209","span":{"begin":267,"end":278},"obj":"NN"},{"id":"T208","span":{"begin":258,"end":266},"obj":"NN"},{"id":"T207","span":{"begin":249,"end":257},"obj":"NN"},{"id":"T206","span":{"begin":237,"end":248},"obj":"NN"},{"id":"T205","span":{"begin":233,"end":236},"obj":"DT"},{"id":"T204","span":{"begin":230,"end":232},"obj":"IN"},{"id":"T203","span":{"begin":219,"end":229},"obj":"VB"},{"id":"T202","span":{"begin":208,"end":218},"obj":"NN"},{"id":"T201","span":{"begin":198,"end":207},"obj":"NN"},{"id":"T200","span":{"begin":194,"end":197},"obj":"DT"},{"id":"T199","span":{"begin":181,"end":193},"obj":"VB"},{"id":"T198","span":{"begin":178,"end":180},"obj":"PRP"},{"id":"T197","span":{"begin":176,"end":177},"obj":"-COMMA-"},{"id":"T196","span":{"begin":172,"end":176},"obj":"NN"},{"id":"T195","span":{"begin":167,"end":171},"obj":"DT"},{"id":"T194","span":{"begin":164,"end":166},"obj":"IN"},{"id":"T193","span":{"begin":161,"end":162},"obj":"-RRB-"},{"id":"T192","span":{"begin":157,"end":161},"obj":"NN"},{"id":"T191","span":{"begin":156,"end":157},"obj":"-LRB-"},{"id":"T190","span":{"begin":147,"end":155},"obj":"NN"},{"id":"T189","span":{"begin":138,"end":146},"obj":"NN"},{"id":"T188","span":{"begin":125,"end":137},"obj":"JJ"},{"id":"T187","span":{"begin":116,"end":124},"obj":"JJ"},{"id":"T186","span":{"begin":112,"end":115},"obj":"CC"},{"id":"T185","span":{"begin":99,"end":111},"obj":"NN"},{"id":"T184","span":{"begin":88,"end":98},"obj":"JJ"},{"id":"T183","span":{"begin":78,"end":87},"obj":"VB"},{"id":"T182","span":{"begin":69,"end":77},"obj":"NN"},{"id":"T181","span":{"begin":61,"end":68},"obj":"JJ"},{"id":"T180","span":{"begin":58,"end":60},"obj":"IN"},{"id":"T179","span":{"begin":45,"end":57},"obj":"NN"},{"id":"T178","span":{"begin":41,"end":44},"obj":"DT"},{"id":"T177","span":{"begin":38,"end":40},"obj":"IN"},{"id":"T176","span":{"begin":27,"end":37},"obj":"VB"},{"id":"T175","span":{"begin":22,"end":26},"obj":"VB"},{"id":"T174","span":{"begin":18,"end":21},"obj":"VB"},{"id":"T173","span":{"begin":13,"end":17},"obj":"WDT"},{"id":"T172","span":{"begin":7,"end":12},"obj":"NN"},{"id":"T171","span":{"begin":2,"end":6},"obj":"NN"}],"relations":[{"id":"R36","pred":"arg1Of","subj":"T172","obj":"T171"},{"id":"R37","pred":"arg2Of","subj":"T176","obj":"T174"},{"id":"R38","pred":"arg2Of","subj":"T176","obj":"T175"},{"id":"R39","pred":"arg1Of","subj":"T176","obj":"T177"},{"id":"R40","pred":"arg2Of","subj":"T179","obj":"T177"},{"id":"R41","pred":"arg1Of","subj":"T179","obj":"T178"},{"id":"R42","pred":"arg1Of","subj":"T179","obj":"T180"},{"id":"R43","pred":"arg2Of","subj":"T182","obj":"T180"},{"id":"R44","pred":"arg1Of","subj":"T182","obj":"T181"},{"id":"R45","pred":"arg1Of","subj":"T182","obj":"T183"},{"id":"R46","pred":"arg1Of","subj":"T185","obj":"T184"},{"id":"R47","pred":"arg1Of","subj":"T185","obj":"T186"},{"id":"R48","pred":"arg2Of","subj":"T186","obj":"T183"},{"id":"R49","pred":"arg2Of","subj":"T190","obj":"T186"},{"id":"R50","pred":"arg1Of","subj":"T190","obj":"T187"},{"id":"R51","pred":"arg1Of","subj":"T190","obj":"T188"},{"id":"R52","pred":"arg1Of","subj":"T190","obj":"T189"},{"id":"R53","pred":"arg1Of","subj":"T190","obj":"T191"},{"id":"R54","pred":"arg2Of","subj":"T192","obj":"T191"},{"id":"R55","pred":"arg3Of","subj":"T193","obj":"T191"},{"id":"R56","pred":"arg2Of","subj":"T196","obj":"T194"},{"id":"R57","pred":"arg1Of","subj":"T196","obj":"T195"},{"id":"R58","pred":"arg1Of","subj":"T198","obj":"T199"},{"id":"R59","pred":"arg1Of","subj":"T199","obj":"T194"},{"id":"R60","pred":"arg1Of","subj":"T199","obj":"T197"},{"id":"R61","pred":"arg2Of","subj":"T202","obj":"T199"},{"id":"R62","pred":"arg1Of","subj":"T202","obj":"T200"},{"id":"R63","pred":"arg1Of","subj":"T202","obj":"T201"},{"id":"R64","pred":"arg2Of","subj":"T202","obj":"T203"},{"id":"R65","pred":"arg2Of","subj":"T212","obj":"T211"},{"id":"R66","pred":"arg3Of","subj":"T213","obj":"T211"},{"id":"R67","pred":"arg1Of","subj":"T214","obj":"T203"},{"id":"R68","pred":"arg2Of","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cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T90","span":{"begin":258,"end":288},"obj":"Protein"},{"id":"T91","span":{"begin":290,"end":294},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T406","span":{"begin":290,"end":294},"obj":"http://www.uniprot.org/uniprot/Q13546"},{"id":"T395","span":{"begin":317,"end":320},"obj":"http://www.uniprot.org/uniprot/Q9Y243"},{"id":"T388","span":{"begin":317,"end":320},"obj":"http://www.uniprot.org/uniprot/P31751"},{"id":"T381","span":{"begin":317,"end":320},"obj":"http://www.uniprot.org/uniprot/P31749"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    UBERON-AE

    {"project":"UBERON-AE","denotations":[{"id":"T58","span":{"begin":88,"end":98},"obj":"http://purl.obolibrary.org/obo/UBERON_0000160"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T129","span":{"begin":321,"end":336},"obj":"http://purl.obolibrary.org/obo/GO_0016301"},{"id":"T127","span":{"begin":198,"end":207},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T126","span":{"begin":125,"end":146},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T125","span":{"begin":99,"end":111},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T124","span":{"begin":45,"end":57},"obj":"http://purl.obolibrary.org/obo/GO_0009405"},{"id":"T121","span":{"begin":7,"end":12},"obj":"http://purl.obolibrary.org/obo/GO_0016265"},{"id":"T118","span":{"begin":2,"end":12},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T110","span":{"begin":353,"end":364},"obj":"http://purl.obolibrary.org/obo/GO_0097528"},{"id":"T109","span":{"begin":237,"end":248},"obj":"http://purl.obolibrary.org/obo/GO_0097528"},{"id":"T102","span":{"begin":353,"end":364},"obj":"http://purl.obolibrary.org/obo/GO_0070266"},{"id":"T101","span":{"begin":237,"end":248},"obj":"http://purl.obolibrary.org/obo/GO_0070266"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    GO-MF

    {"project":"GO-MF","denotations":[{"id":"T135","span":{"begin":321,"end":336},"obj":"http://purl.obolibrary.org/obo/GO_0016301"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T137","span":{"begin":2,"end":6},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    sentences

    {"project":"sentences","denotations":[{"id":"T62","span":{"begin":164,"end":303},"obj":"Sentence"},{"id":"T5","span":{"begin":164,"end":303},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    simple1

    {"project":"simple1","denotations":[{"id":"T145","span":{"begin":258,"end":288},"obj":"Protein"},{"id":"T146","span":{"begin":290,"end":294},"obj":"Protein"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T355","span":{"begin":258,"end":288},"obj":"Protein"},{"id":"T356","span":{"begin":290,"end":294},"obj":"Protein"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T443","span":{"begin":258,"end":288},"obj":"Protein"},{"id":"T444","span":{"begin":290,"end":294},"obj":"Protein"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    DLUT931

    {"project":"DLUT931","denotations":[{"id":"T412","span":{"begin":258,"end":288},"obj":"Protein"},{"id":"T413","span":{"begin":290,"end":294},"obj":"Protein"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    bionlp-st-ge-2016-test-ihmc

    {"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T748","span":{"begin":230,"end":302},"obj":"Protein"},{"id":"T746","span":{"begin":290,"end":294},"obj":"Protein"},{"id":"T743","span":{"begin":317,"end":320},"obj":"Protein"},{"id":"T742","span":{"begin":317,"end":327},"obj":"Protein"},{"id":"T736","span":{"begin":258,"end":295},"obj":"Protein"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    bionlp-st-ge-2016-spacy-parsed

    {"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T533","span":{"begin":178,"end":180},"obj":"PRP"},{"id":"T532","span":{"begin":176,"end":177},"obj":","},{"id":"T531","span":{"begin":172,"end":176},"obj":"NN"},{"id":"T530","span":{"begin":167,"end":171},"obj":"DT"},{"id":"T529","span":{"begin":164,"end":166},"obj":"IN"},{"id":"T528","span":{"begin":162,"end":163},"obj":"."},{"id":"T527","span":{"begin":161,"end":162},"obj":"-RRB-"},{"id":"T526","span":{"begin":157,"end":161},"obj":"NNP"},{"id":"T525","span":{"begin":156,"end":157},"obj":"-LRB-"},{"id":"T524","span":{"begin":147,"end":155},"obj":"NN"},{"id":"T523","span":{"begin":138,"end":146},"obj":"NN"},{"id":"T522","span":{"begin":125,"end":137},"obj":"JJ"},{"id":"T521","span":{"begin":116,"end":124},"obj":"JJ"},{"id":"T520","span":{"begin":112,"end":115},"obj":"CC"},{"id":"T519","span":{"begin":99,"end":111},"obj":"NN"},{"id":"T518","span":{"begin":88,"end":98},"obj":"JJ"},{"id":"T517","span":{"begin":78,"end":87},"obj":"VBG"},{"id":"T516","span":{"begin":69,"end":77},"obj":"NNS"},{"id":"T515","span":{"begin":61,"end":68},"obj":"JJ"},{"id":"T514","span":{"begin":58,"end":60},"obj":"IN"},{"id":"T513","span":{"begin":45,"end":57},"obj":"NN"},{"id":"T512","span":{"begin":41,"end":44},"obj":"DT"},{"id":"T511","span":{"begin":38,"end":40},"obj":"IN"},{"id":"T510","span":{"begin":27,"end":37},"obj":"VBN"},{"id":"T509","span":{"begin":22,"end":26},"obj":"VBN"},{"id":"T508","span":{"begin":18,"end":21},"obj":"VBZ"},{"id":"T507","span":{"begin":13,"end":17},"obj":"WDT"},{"id":"T506","span":{"begin":7,"end":12},"obj":"NN"},{"id":"T505","span":{"begin":2,"end":6},"obj":"NN"},{"id":"T562","span":{"begin":368,"end":372},"obj":"CD"},{"id":"T561","span":{"begin":365,"end":367},"obj":"IN"},{"id":"T560","span":{"begin":353,"end":364},"obj":"NN"},{"id":"T559","span":{"begin":349,"end":352},"obj":"IN"},{"id":"T558","span":{"begin":340,"end":348},"obj":"JJ"},{"id":"T557","span":{"begin":337,"end":339},"obj":"VBZ"},{"id":"T556","span":{"begin":328,"end":336},"obj":"NN"},{"id":"T555","span":{"begin":321,"end":327},"obj":"NN"},{"id":"T554","span":{"begin":317,"end":320},"obj":"NNP"},{"id":"T553","span":{"begin":312,"end":316},"obj":"IN"},{"id":"T552","span":{"begin":307,"end":311},"obj":"VBP"},{"id":"T551","span":{"begin":304,"end":306},"obj":"PRP"},{"id":"T550","span":{"begin":302,"end":303},"obj":"."},{"id":"T549","span":{"begin":296,"end":302},"obj":"NN"},{"id":"T548","span":{"begin":294,"end":295},"obj":"-RRB-"},{"id":"T547","span":{"begin":290,"end":294},"obj":"CD"},{"id":"T546","span":{"begin":289,"end":290},"obj":"-LRB-"},{"id":"T545","span":{"begin":279,"end":288},"obj":"NN"},{"id":"T544","span":{"begin":267,"end":278},"obj":"VBG"},{"id":"T543","span":{"begin":258,"end":266},"obj":"NN"},{"id":"T542","span":{"begin":249,"end":257},"obj":"NN"},{"id":"T541","span":{"begin":237,"end":248},"obj":"NN"},{"id":"T540","span":{"begin":233,"end":236},"obj":"DT"},{"id":"T539","span":{"begin":230,"end":232},"obj":"IN"},{"id":"T538","span":{"begin":219,"end":229},"obj":"VBN"},{"id":"T537","span":{"begin":208,"end":218},"obj":"NNS"},{"id":"T536","span":{"begin":198,"end":207},"obj":"VBG"},{"id":"T535","span":{"begin":194,"end":197},"obj":"DT"},{"id":"T534","span":{"begin":181,"end":193},"obj":"VBD"}],"relations":[{"id":"R245","pred":"compound","subj":"T505","obj":"T506"},{"id":"R247","pred":"nsubjpass","subj":"T507","obj":"T510"},{"id":"R248","pred":"aux","subj":"T508","obj":"T510"},{"id":"R249","pred":"auxpass","subj":"T509","obj":"T510"},{"id":"R250","pred":"relcl","subj":"T510","obj":"T506"},{"id":"R251","pred":"prep","subj":"T511","obj":"T510"},{"id":"R252","pred":"det","subj":"T512","obj":"T513"},{"id":"R253","pred":"pobj","subj":"T513","obj":"T511"},{"id":"R254","pred":"prep","subj":"T514","obj":"T513"},{"id":"R255","pred":"amod","subj":"T515","obj":"T516"},{"id":"R256","pred":"pobj","subj":"T516","obj":"T514"},{"id":"R257","pred":"prep","subj":"T517","obj":"T516"},{"id":"R258","pred":"amod","subj":"T518","obj":"T519"},{"id":"R259","pred":"pobj","subj":"T519","obj":"T517"},{"id":"R260","pred":"cc","subj":"T520","obj":"T519"},{"id":"R261","pred":"amod","subj":"T521","obj":"T524"},{"id":"R262","pred":"amod","subj":"T522","obj":"T523"},{"id":"R263","pred":"compound","subj":"T523","obj":"T524"},{"id":"R264","pred":"conj","subj":"T524","obj":"T519"},{"id":"R265","pred":"punct","subj":"T525","obj":"T524"},{"id":"R266","pred":"appos","subj":"T526","obj":"T524"},{"id":"R267","pred":"punct","subj":"T527","obj":"T524"},{"id":"R269","pred":"prep","subj":"T529","obj":"T534"},{"id":"R270","pred":"det","subj":"T530","obj":"T531"},{"id":"R271","pred":"pobj","subj":"T531","obj":"T529"},{"id":"R272","pred":"punct","subj":"T532","obj":"T534"},{"id":"R273","pred":"nsubj","subj":"T533","obj":"T534"},{"id":"R274","pred":"ROOT","subj":"T534","obj":"T534"},{"id":"R275","pred":"det","subj":"T535","obj":"T537"},{"id":"R276","pred":"amod","subj":"T536","obj":"T537"},{"id":"R277","pred"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cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    bionlp-st-ge-2016-test-tees

    {"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T466","span":{"begin":317,"end":327},"obj":"Protein"},{"id":"T465","span":{"begin":219,"end":229},"obj":"Regulation"},{"id":"T464","span":{"begin":219,"end":229},"obj":"Regulation"},{"id":"T463","span":{"begin":290,"end":294},"obj":"Protein"},{"id":"T462","span":{"begin":249,"end":288},"obj":"Protein"}],"relations":[{"id":"R216","pred":"themeOf","subj":"T462","obj":"T464"},{"id":"R217","pred":"themeOf","subj":"T463","obj":"T465"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}

    test3

    {"project":"test3","denotations":[{"id":"T45","span":{"begin":290,"end":294},"obj":"Protein"},{"id":"T44","span":{"begin":258,"end":288},"obj":"Protein"},{"id":"T43","span":{"begin":219,"end":229},"obj":"Regulation"},{"id":"T32","span":{"begin":290,"end":294},"obj":"Protein"},{"id":"T31","span":{"begin":258,"end":288},"obj":"Protein"}],"relations":[{"id":"R8","pred":"causeOf","subj":"T44","obj":"T43"},{"id":"R9","pred":"equivalentTo","subj":"T45","obj":"T44"}],"text":"c cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase. We show that Akt kinase activity is critical for necroptosis in L929 c"}