PMC:3585731 / 15366-15762
Annnotations
testone
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5142 | 304-314 | Positive_regulation | denotes | activation |
T5141 | 241-249 | Positive_regulation | denotes | increase |
T5140 | 219-226 | Negative_regulation | denotes | blocked |
T5139 | 109-118 | Positive_regulation | denotes | triggered |
T5138 | 93-108 | Phosphorylation | denotes | phosphorylation |
T5137 | 58-66 | Positive_regulation | denotes | increase |
T5136 | 38-44 | Regulation | denotes | effect |
T5087 | 375-379 | Protein | denotes | RIP1 |
T5086 | 231-235 | Protein | denotes | bFGF |
T5085 | 136-140 | Protein | denotes | bFGF |
T5084 | 127-131 | Protein | denotes | bFGF |
T5083 | 87-92 | Protein | denotes | c-Jun |
R3511 | T5083 | T5138 | themeOf | c-Jun,phosphorylation |
R3512 | T5084 | T5139 | causeOf | bFGF,triggered |
R3513 | T5085 | T5139 | causeOf | bFGF,triggered |
R3514 | T5086 | T5141 | themeOf | bFGF,increase |
R3530 | T5137 | T5136 | themeOf | increase,effect |
R3531 | T5138 | T5139 | themeOf | phosphorylation,triggered |
R3532 | T5138 | T5137 | themeOf | phosphorylation,increase |
R3533 | T5141 | T5140 | themeOf | increase,blocked |
bionlp-st-ge-2016-test-proteins
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5398 | 375-379 | Protein | denotes | RIP1 |
T5397 | 231-235 | Protein | denotes | bFGF |
T5396 | 136-140 | Protein | denotes | bFGF |
T5395 | 127-131 | Protein | denotes | bFGF |
T5394 | 87-92 | Protein | denotes | c-Jun |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6487 | 318-321 | http://www.uniprot.org/uniprot/P31751 | denotes | Akt |
T6486 | 75-78 | http://www.uniprot.org/uniprot/P31751 | denotes | Akt |
T6433 | 375-379 | http://www.uniprot.org/uniprot/Q13546 | denotes | RIP1 |
T6526 | 231-235 | http://www.uniprot.org/uniprot/Q788Q8 | denotes | bFGF |
T6525 | 136-140 | http://www.uniprot.org/uniprot/Q788Q8 | denotes | bFGF |
T6524 | 127-131 | http://www.uniprot.org/uniprot/Q788Q8 | denotes | bFGF |
T6515 | 318-321 | http://www.uniprot.org/uniprot/Q9Y243 | denotes | Akt |
T6514 | 75-78 | http://www.uniprot.org/uniprot/Q9Y243 | denotes | Akt |
T6459 | 318-321 | http://www.uniprot.org/uniprot/P31749 | denotes | Akt |
T6458 | 75-78 | http://www.uniprot.org/uniprot/P31749 | denotes | Akt |
T6539 | 87-92 | http://www.uniprot.org/uniprot/P05412 | denotes | c-Jun |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5488 | 380-395 | http://purl.obolibrary.org/obo/GO_0016301 | denotes | kinase activity |
T5476 | 93-108 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T5459 | 326-329 | http://purl.obolibrary.org/obo/GO_0004705 | denotes | JNK |
T5458 | 83-86 | http://purl.obolibrary.org/obo/GO_0004705 | denotes | JNK |
T5419 | 346-357 | http://purl.obolibrary.org/obo/GO_0097528 | denotes | necroptosis |
T5409 | 346-357 | http://purl.obolibrary.org/obo/GO_0070266 | denotes | necroptosis |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5509 | 380-395 | http://purl.obolibrary.org/obo/GO_0016301 | denotes | kinase activity |
T5507 | 326-329 | http://purl.obolibrary.org/obo/GO_0004705 | denotes | JNK |
T5506 | 83-86 | http://purl.obolibrary.org/obo/GO_0004705 | denotes | JNK |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T98 | 0-396 | Sentence | denotes | Furthermore, Nec-1 had no significant effect on the early increase in both Akt and JNK/c-Jun phosphorylation triggered by both bFGF and bFGF/zVAD, while Nec-1, but not its inactive analog Nec-1i (Fig. S1E), efficiently blocked the bFGF/zVAD increase at 6–9 hr (Fig. 3D), suggesting that only the delayed activation of Akt and JNK is specific for necroptosis and dependent on RIP1 kinase activity. |
simple1
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5551 | 375-379 | Protein | denotes | RIP1 |
T5550 | 231-235 | Protein | denotes | bFGF |
T5549 | 136-140 | Protein | denotes | bFGF |
T5548 | 127-131 | Protein | denotes | bFGF |
T5547 | 87-92 | Protein | denotes | c-Jun |
BioNLP16_DUT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6428 | 219-226 | Negative_regulation | denotes | blocked |
T6427 | 58-66 | Positive_regulation | denotes | increase |
T6426 | 362-371 | Positive_regulation | denotes | dependent |
T6425 | 241-249 | Positive_regulation | denotes | increase |
T6424 | 93-108 | Phosphorylation | denotes | phosphorylation |
T6410 | 375-379 | Protein | denotes | RIP1 |
T6409 | 231-235 | Protein | denotes | bFGF |
T6408 | 136-140 | Protein | denotes | bFGF |
T6407 | 127-131 | Protein | denotes | bFGF |
T6406 | 87-92 | Protein | denotes | c-Jun |
R4412 | T6406 | T6424 | themeOf | c-Jun,phosphorylation |
R4413 | T6409 | T6425 | themeOf | bFGF,increase |
R4414 | T6410 | T6426 | themeOf | RIP1,dependent |
R4420 | T6424 | T6427 | themeOf | phosphorylation,increase |
R4421 | T6425 | T6428 | themeOf | increase,blocked |
BioNLP16_Messiy
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6708 | 241-249 | Positive_regulation | denotes | increase |
T6707 | 219-226 | Negative_regulation | denotes | blocked |
T6691 | 375-379 | Protein | denotes | RIP1 |
T6690 | 231-235 | Protein | denotes | bFGF |
T6689 | 136-140 | Protein | denotes | bFGF |
T6688 | 127-131 | Protein | denotes | bFGF |
T6687 | 87-92 | Protein | denotes | c-Jun |
R4491 | T6690 | T6708 | themeOf | bFGF,increase |
R4498 | T6708 | T6707 | themeOf | increase,blocked |
DLUT931
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6593 | 219-226 | Negative_regulation | denotes | blocked |
T6592 | 241-249 | Positive_regulation | denotes | increase |
T6591 | 109-118 | Positive_regulation | denotes | triggered |
T6590 | 93-108 | Phosphorylation | denotes | phosphorylation |
T6571 | 375-379 | Protein | denotes | RIP1 |
T6570 | 231-235 | Protein | denotes | bFGF |
T6569 | 136-140 | Protein | denotes | bFGF |
T6568 | 127-131 | Protein | denotes | bFGF |
T6567 | 87-92 | Protein | denotes | c-Jun |
R4438 | T6567 | T6590 | themeOf | c-Jun,phosphorylation |
R4439 | T6568 | T6591 | themeOf | bFGF,triggered |
R4440 | T6569 | T6591 | causeOf | bFGF,triggered |
R4441 | T6570 | T6592 | themeOf | bFGF,increase |
R4452 | T6592 | T6593 | themeOf | increase,blocked |
bionlp-st-ge-2016-test-ihmc
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T7285 | 292-329 | Positive_regulation | denotes | the delayed activation of Akt and JNK |
T7284 | 292-329 | Positive_regulation | denotes | the delayed activation of Akt and JNK |
T7278 | 292-329 | Negative_regulation | denotes | the delayed activation of Akt and JNK |
T7277 | 292-329 | Negative_regulation | denotes | the delayed activation of Akt and JNK |
T7246 | 362-395 | Protein | denotes | dependent on RIP1 kinase activity |
T7227 | 318-321 | Protein | denotes | Akt |
T7192 | 375-379 | Protein | denotes | RIP1 |
T7174 | 326-329 | Protein | denotes | JNK |
R4714 | T7174 | T7285 | themeOf | JNK,the delayed activation of Akt and JNK |
R4746 | T7227 | T7284 | themeOf | Akt,the delayed activation of Akt and JNK |
R4772 | T7284 | T7277 | themeOf | the delayed activation of Akt and JNK,the delayed activation of Akt and JNK |
R4773 | T7285 | T7278 | themeOf | the delayed activation of Akt and JNK,the delayed activation of Akt and JNK |
bionlp-st-ge-2016-test-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6897 | 219-226 | Negative_regulation | denotes | blocked |
T6896 | 219-226 | Negative_regulation | denotes | blocked |
T6895 | 58-66 | Positive_regulation | denotes | increase |
T6894 | 58-66 | Positive_regulation | denotes | increase |
T6893 | 58-66 | Positive_regulation | denotes | increase |
T6892 | 304-314 | Positive_regulation | denotes | activation |
T6891 | 304-314 | Positive_regulation | denotes | activation |
T6890 | 241-249 | Positive_regulation | denotes | increase |
T6889 | 93-108 | Phosphorylation | denotes | phosphorylation |
T6888 | 93-108 | Phosphorylation | denotes | phosphorylation |
T6887 | 93-108 | Phosphorylation | denotes | phosphorylation |
T6886 | 58-66 | Positive_regulation | denotes | increase |
T6885 | 375-386 | Protein | denotes | RIP1 kinase |
T6884 | 326-329 | Protein | denotes | JNK |
T6883 | 318-321 | Protein | denotes | Akt |
T6882 | 231-240 | Protein | denotes | bFGF/zVAD |
T6881 | 201-204 | Protein | denotes | S1E |
T6880 | 196-199 | Protein | denotes | Fig |
T6879 | 181-194 | Protein | denotes | analog Nec-1i |
T6878 | 153-158 | Protein | denotes | Nec-1 |
T6877 | 141-145 | Protein | denotes | zVAD |
T6876 | 136-140 | Protein | denotes | bFGF |
T6875 | 127-131 | Protein | denotes | bFGF |
T6874 | 87-92 | Protein | denotes | c-Jun |
T6873 | 83-86 | Protein | denotes | JNK |
T6872 | 75-78 | Protein | denotes | Akt |
T6871 | 13-18 | Protein | denotes | Nec-1 |
R4574 | T6871 | T6886 | causeOf | Nec-1,increase |
R4575 | T6871 | T6893 | causeOf | Nec-1,increase |
R4576 | T6871 | T6894 | causeOf | Nec-1,increase |
R4577 | T6871 | T6895 | causeOf | Nec-1,increase |
R4578 | T6872 | T6886 | themeOf | Akt,increase |
R4579 | T6872 | T6887 | themeOf | Akt,phosphorylation |
R4581 | T6873 | T6888 | themeOf | JNK,phosphorylation |
R4584 | T6874 | T6889 | themeOf | c-Jun,phosphorylation |
R4586 | T6878 | T6896 | causeOf | Nec-1,blocked |
R4588 | T6879 | T6897 | causeOf | analog Nec-1i,blocked |
R4590 | T6882 | T6890 | themeOf | bFGF/zVAD,increase |
R4592 | T6883 | T6891 | themeOf | Akt,activation |
R4594 | T6884 | T6892 | themeOf | JNK,activation |
R4597 | T6887 | T6893 | themeOf | phosphorylation,increase |
R4598 | T6888 | T6894 | themeOf | phosphorylation,increase |
R4599 | T6889 | T6895 | themeOf | phosphorylation,increase |
R4600 | T6890 | T6896 | themeOf | increase,blocked |
R4601 | T6890 | T6897 | themeOf | increase,blocked |
test3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5266 | 375-379 | Protein | denotes | RIP1 |
T5265 | 304-314 | Positive_regulation | denotes | activation |
T5264 | 241-249 | Positive_regulation | denotes | increase |
T5263 | 231-235 | Protein | denotes | bFGF |
T5262 | 136-140 | Protein | denotes | bFGF |
T5261 | 127-131 | Protein | denotes | bFGF |
T5260 | 109-118 | Positive_regulation | denotes | triggered |
T5259 | 93-108 | Phosphorylation | denotes | phosphorylation |
T5258 | 87-92 | Protein | denotes | c-Jun |
T5257 | 58-66 | Positive_regulation | denotes | increase |
T5256 | 38-44 | Regulation | denotes | effect |
T5183 | 375-379 | Protein | denotes | RIP1 |
T5182 | 231-235 | Protein | denotes | bFGF |
T5181 | 136-140 | Protein | denotes | bFGF |
T5180 | 127-131 | Protein | denotes | bFGF |
T5179 | 87-92 | Protein | denotes | c-Jun |
R3569 | T5258 | T5259 | themeOf | c-Jun,phosphorylation |
R3570 | T5259 | T5257 | themeOf | phosphorylation,increase |
R3571 | T5260 | T5257 | themeOf | triggered,increase |
R3572 | T5261 | T5260 | causeOf | bFGF,triggered |
R3573 | T5262 | T5260 | causeOf | bFGF,triggered |
R3574 | T5263 | T5264 | causeOf | bFGF,increase |