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PMC:3585731 / 14418-16461 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T5151 1906-1921 Phosphorylation denotes phosphorylation
T5150 1881-1890 Positive_regulation denotes increases
T5149 1785-1800 Phosphorylation denotes phosphorylation
T5148 1762-1770 Positive_regulation denotes increase
T5147 1633-1648 Phosphorylation denotes phosphorylation
T5146 1550-1565 Phosphorylation denotes phosphorylation
T5145 1538-1546 Positive_regulation denotes increase
T5144 1464-1479 Phosphorylation denotes phosphorylation
T5143 1445-1453 Positive_regulation denotes increase
T5142 1252-1262 Positive_regulation denotes activation
T5141 1189-1197 Positive_regulation denotes increase
T5140 1167-1174 Negative_regulation denotes blocked
T5139 1057-1066 Positive_regulation denotes triggered
T5138 1041-1056 Phosphorylation denotes phosphorylation
T5137 1006-1014 Positive_regulation denotes increase
T5136 986-992 Regulation denotes effect
T5135 900-908 Positive_regulation denotes increase
T5134 829-844 Phosphorylation denotes phosphorylation
T5133 813-821 Positive_regulation denotes increase
T5132 780-786 Positive_regulation denotes caused
T5131 570-585 Phosphorylation denotes phosphorylation
T5130 535-543 Positive_regulation denotes increase
T5129 307-317 Regulation denotes regulation
T5128 97-106 Positive_regulation denotes following
T5127 38-53 Phosphorylation denotes phosphorylation
T5089 2031-2035 Protein denotes RIP1
T5088 1747-1751 Protein denotes RIP1
T5087 1323-1327 Protein denotes RIP1
T5086 1179-1183 Protein denotes bFGF
T5085 1084-1088 Protein denotes bFGF
T5084 1075-1079 Protein denotes bFGF
T5083 1035-1040 Protein denotes c-Jun
T5082 763-767 Protein denotes bFGF
T5081 740-744 Protein denotes bFGF
T5080 612-617 Protein denotes c-Jun
T5079 451-455 Protein denotes bFGF
T5078 280-284 Protein denotes RIP1
R3510 T5080 T5131 themeOf c-Jun,phosphorylation
R3511 T5083 T5138 themeOf c-Jun,phosphorylation
R3512 T5084 T5139 causeOf bFGF,triggered
R3513 T5085 T5139 causeOf bFGF,triggered
R3514 T5086 T5141 themeOf bFGF,increase
R3515 T5088 T5148 causeOf RIP1,increase
R3527 T5127 T5128 themeOf phosphorylation,following
R3528 T5131 T5130 themeOf phosphorylation,increase
R3529 T5134 T5133 themeOf phosphorylation,increase
R3530 T5137 T5136 themeOf increase,effect
R3531 T5138 T5139 themeOf phosphorylation,triggered
R3532 T5138 T5137 themeOf phosphorylation,increase
R3533 T5141 T5140 themeOf increase,blocked
R3534 T5144 T5143 themeOf phosphorylation,increase
R3535 T5146 T5145 themeOf phosphorylation,increase
R3536 T5149 T5148 themeOf phosphorylation,increase
R3537 T5151 T5150 themeOf phosphorylation,increases

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T6320 1873-1880 VB denotes delayed
T6319 1864-1872 VB denotes observed
T6318 1860-1863 DT denotes the
T6317 1855-1859 IN denotes that
T6316 1846-1854 VB denotes indicate
T6315 1838-1845 NN denotes results
T6314 1832-1837 DT denotes these
T6313 1830-1831 -COMMA- denotes ,
T6312 1822-1830 RB denotes together
T6311 1816-1821 VB denotes Taken
T6310 1813-1814 -RRB- denotes )
T6309 1812-1813 NN denotes E
T6308 1810-1811 -COMMA- denotes ,
T6307 1807-1810 NN denotes S3D
T6306 1802-1806 NNP denotes Fig.
T6305 1801-1802 -LRB- denotes (
T6304 1785-1800 NN denotes phosphorylation
T6303 1778-1784 NN denotes Thr308
T6302 1774-1777 NN denotes Akt
T6301 1771-1773 IN denotes in
T6300 1762-1770 NN denotes increase
T6299 1747-1761 JJ denotes RIP1-dependent
T6298 1726-1746 JJ denotes necroptosis-specific
T6297 1718-1725 VB denotes delayed
T6296 1711-1717 JJ denotes robust
T6295 1709-1710 DT denotes a
T6294 1702-1708 VB denotes showed
T6293 1697-1701 RB denotes also
T6292 1691-1696 WDT denotes which
T6291 1689-1690 -COMMA- denotes ,
T6290 1684-1689 NN denotes assay
T6289 1678-1683 NN denotes ELISA
T6288 1665-1677 JJ denotes quantitative
T6287 1663-1664 DT denotes a
T6286 1657-1662 VB denotes using
T6285 1649-1656 NN denotes changes
T6284 1633-1648 NN denotes phosphorylation
T6283 1626-1632 NN denotes Ser473
T6282 1622-1625 CC denotes and
T6281 1615-1621 NN denotes Thr308
T6280 1611-1614 NN denotes Akt
T6279 1607-1610 DT denotes the
T6278 1604-1606 IN denotes of
T6277 1595-1603 NN denotes kinetics
T6276 1591-1594 DT denotes the
T6275 1581-1590 VB denotes confirmed
T6274 1578-1580 PRP denotes We
T6273 1575-1576 -RRB- denotes )
T6272 1572-1575 NN denotes S3C
T6271 1567-1571 NN denotes Fig.
T6270 1566-1567 -LRB- denotes (
T6269 1550-1565 NN denotes phosphorylation
T6268 1547-1549 IN denotes in
T6267 1538-1546 NN denotes increase
T6266 1528-1537 JJ denotes transient
T6265 1526-1527 -COMMA- denotes ,
T6264 1521-1526 JJ denotes early
T6263 1518-1520 DT denotes an
T6262 1511-1517 RB denotes solely
T6261 1504-1510 VB denotes caused
T6260 1498-1503 RB denotes alone
T6259 1494-1497 NN denotes IGF
T6258 1488-1493 IN denotes while
T6257 1486-1487 -COMMA- denotes ,
T6256 1483-1486 NNP denotes Akt
T6255 1480-1482 IN denotes on
T6254 1464-1479 NN denotes phosphorylation
T6253 1457-1463 NN denotes Thr308
T6252 1454-1456 IN denotes in
T6251 1445-1453 NN denotes increase
T6250 1437-1444 VB denotes delayed
T6249 1435-1436 DT denotes a
T6248 1426-1434 VB denotes produced
T6247 1424-1425 -COMMA- denotes ,
T6246 1414-1424 NN denotes conditions
T6245 1409-1413 JJ denotes free
T6244 1403-1408 NN denotes serum
T6243 1397-1402 IN denotes under
T6242 1391-1396 NN denotes death
T6241 1386-1390 NN denotes cell
T6240 1377-1385 VB denotes promoted
T6239 1372-1376 RB denotes also
T6238 1366-1371 WDT denotes which
T6237 1364-1365 -COMMA- denotes ,
T6236 1356-1364 NN denotes IGF/zVAD
T6235 1354-1355 -COMMA- denotes ,
T6234 1345-1354 RB denotes Similarly
T6233 703-704 -RRB- denotes )
T6232 701-703 NN denotes 3C
T6231 696-700 NN denotes Fig.
T6230 695-696 -LRB- denotes (
T6229 683-694 NN denotes stimulation
T6228 676-682 NN denotes factor
T6227 669-675 NN denotes growth
T6226 666-668 TO denotes to
T6225 657-665 NN denotes response
T6224 648-656 JJ denotes expected
T6223 644-647 DT denotes the
T6222 633-643 VB denotes reflecting
T6221 631-632 -COMMA- denotes ,
T6220 624-631 NN denotes minutes
T6219 621-623 CD denotes 15
T6218 618-620 IN denotes at
T6217 612-617 NN denotes c-Jun
T6216 608-611 CC denotes and
T6215 604-607 NN denotes JNK
T6214 601-603 IN denotes as
T6213 596-600 RB denotes well
T6212 593-595 RB denotes as
T6211 589-592 NN denotes Akt
T6210 586-588 IN denotes of
T6209 570-585 NN denotes phosphorylation
T6208 563-569 NN denotes Ser473
T6207 559-562 CC denotes and
T6206 552-558 NN denotes Thr308
T6205 547-551 CC denotes both
T6204 544-546 IN denotes in
T6203 535-543 NN denotes increase
T6202 525-534 JJ denotes transient
T6201 521-524 CC denotes and
T6200 515-520 JJ denotes rapid
T6199 503-514 JJ denotes substantial
T6198 501-502 DT denotes a
T6197 498-500 TO denotes to
T6196 494-497 VB denotes led
T6195 485-493 NN denotes zVAD.fmk
T6194 480-484 IN denotes with
T6193 468-479 NN denotes combination
T6192 465-467 IN denotes in
T6191 462-464 CC denotes or
T6190 456-461 RB denotes alone
T6189 451-455 NN denotes bFGF
T6188 448-450 IN denotes of
T6187 439-447 NN denotes addition
T6186 435-438 DT denotes the
T6185 430-434 IN denotes that
T6184 424-429 VB denotes found
T6183 421-423 PRP denotes We
T6182 409-419 NN denotes conditions
T6181 404-408 JJ denotes free
T6180 398-403 NN denotes serum
T6179 392-397 IN denotes under
T6178 384-391 NN denotes changes
T6177 368-383 NN denotes phosphorylation
T6176 362-367 DT denotes these
T6175 359-361 IN denotes of
T6174 352-358 NN denotes course
T6173 347-351 NN denotes time
T6172 343-346 DT denotes the
T6171 334-342 VB denotes analyzed
T6170 329-333 RB denotes next
T6169 326-328 PRP denotes we
T6168 324-325 -COMMA- denotes ,
T6167 321-324 NN denotes Akt
T6166 318-320 IN denotes of
T6165 307-317 NN denotes regulation
T6164 295-306 JJ denotes necroptotic
T6163 292-294 TO denotes to
T6162 285-291 NN denotes kinase
T6161 280-284 NN denotes RIP1
T6160 276-279 CC denotes and
T6159 268-275 NN denotes factors
T6158 261-267 NN denotes growth
T6157 258-260 IN denotes of
T6156 244-257 NN denotes contributions
T6155 240-243 DT denotes the
T6154 229-239 VB denotes understand
T6153 222-228 RB denotes better
T6152 219-221 TO denotes To
T6151 216-217 -RRB- denotes )
T6150 213-216 NN denotes S3A
T6149 208-212 NNP denotes Fig.
T6148 207-208 -LRB- denotes (
T6147 190-206 NN denotes post-stimulation
T6146 187-189 NN denotes hr
T6145 185-186 CD denotes 6
T6144 182-184 IN denotes at
T6143 170-181 NN denotes necroptosis
T6142 167-169 IN denotes of
T6141 161-166 NN denotes onset
T6140 157-160 DT denotes the
T6139 152-156 IN denotes with
T6138 143-151 VB denotes coincide
T6137 138-142 WDT denotes that
T6136 136-137 -RRB- denotes )
T6135 134-136 NN denotes 3B
T6134 129-133 NN denotes Fig.
T6133 128-129 -LRB- denotes (
T6132 116-127 NN denotes stimulation
T6131 107-115 NN denotes zVAD.fmk
T6130 97-106 VB denotes following
T6129 90-96 NN denotes events
T6128 85-89 JJ denotes late
T6127 81-84 VB denotes are
T6126 77-80 NN denotes Jun
T6125 73-76 CC denotes and
T6124 69-72 NN denotes JNK
T6123 67-68 -COMMA- denotes ,
T6122 61-67 NN denotes Thr308
T6121 57-60 NNP denotes Akt
T6120 54-56 IN denotes of
T6119 38-53 NN denotes phosphorylation
T6118 34-37 DT denotes the
T6117 29-33 IN denotes that
T6116 18-28 VB denotes discovered
T6115 15-17 PRP denotes we
T6114 13-14 -COMMA- denotes ,
T6113 0-13 RB denotes Interestingly
T6344 2036-2042 NN denotes kinase
T6343 2031-2035 NN denotes RIP1
T6342 2026-2030 IN denotes from
T6341 2015-2025 RB denotes downstream
T6340 2005-2014 NN denotes signaling
T6339 1993-2004 JJ denotes necroptotic
T6338 1990-1992 IN denotes of
T6337 1977-1989 NN denotes consequences
T6336 1968-1976 JJ denotes specific
T6335 1958-1967 VB denotes represent
T6334 1956-1957 -COMMA- denotes ,
T6333 1951-1956 NN denotes death
T6332 1946-1950 NN denotes cell
T6331 1943-1945 IN denotes of
T6330 1937-1942 NN denotes onset
T6329 1933-1936 DT denotes the
T6328 1923-1932 VB denotes preceding
T6327 1921-1922 -COMMA- denotes ,
T6326 1906-1921 NN denotes phosphorylation
T6325 1902-1905 NN denotes JNK
T6324 1898-1901 CC denotes and
T6323 1894-1897 NN denotes Akt
T6322 1891-1893 IN denotes in
T6321 1881-1890 NN denotes increases
R4163 T6115 T6116 arg1Of we,discovered
R4164 T6116 T6113 arg1Of discovered,Interestingly
R4165 T6116 T6114 arg1Of discovered,","
R4166 T6119 T6118 arg1Of phosphorylation,the
R4167 T6119 T6120 arg1Of phosphorylation,of
R4168 T6119 T6127 arg1Of phosphorylation,are
R4169 T6122 T6121 arg1Of Thr308,Akt
R4170 T6122 T6123 arg1Of Thr308,","
R4171 T6123 T6125 arg1Of ",",and
R4172 T6124 T6123 arg2Of JNK,","
R4173 T6125 T6120 arg2Of and,of
R4174 T6126 T6125 arg2Of Jun,and
R4175 T6127 T6116 arg2Of are,discovered
R4176 T6127 T6117 arg1Of are,that
R4177 T6129 T6127 arg2Of events,are
R4178 T6129 T6128 arg1Of events,late
R4179 T6129 T6130 arg1Of events,following
R4180 T6129 T6137 arg1Of events,that
R4181 T6129 T6138 arg1Of events,coincide
R4182 T6132 T6130 arg2Of stimulation,following
R4183 T6132 T6131 arg1Of stimulation,zVAD.fmk
R4184 T6132 T6133 arg1Of stimulation,(
R4185 T6135 T6133 arg2Of 3B,(
R4186 T6135 T6134 arg1Of 3B,Fig.
R4187 T6136 T6133 arg3Of ),(
R4188 T6138 T6139 arg1Of coincide,with
R4189 T6141 T6139 arg2Of onset,with
R4190 T6141 T6140 arg1Of onset,the
R4191 T6141 T6142 arg1Of onset,of
R4192 T6141 T6144 arg1Of onset,at
R4193 T6143 T6142 arg2Of necroptosis,of
R4194 T6147 T6144 arg2Of post-stimulation,at
R4195 T6147 T6145 arg1Of post-stimulation,6
R4196 T6147 T6146 arg1Of post-stimulation,hr
R4197 T6147 T6148 arg1Of post-stimulation,(
R4198 T6150 T6148 arg2Of S3A,(
R4199 T6150 T6149 arg1Of S3A,Fig.
R4200 T6151 T6148 arg3Of ),(
R4201 T6154 T6152 arg1Of understand,To
R4202 T6154 T6153 arg1Of understand,better
R4203 T6154 T6163 arg1Of understand,to
R4204 T6156 T6154 arg2Of contributions,understand
R4205 T6156 T6155 arg1Of contributions,the
R4206 T6156 T6157 arg1Of contributions,of
R4207 T6159 T6158 arg1Of factors,growth
R4208 T6159 T6160 arg1Of factors,and
R4209 T6160 T6157 arg2Of and,of
R4210 T6162 T6160 arg2Of kinase,and
R4211 T6162 T6161 arg1Of kinase,RIP1
R4212 T6165 T6163 arg2Of regulation,to
R4213 T6165 T6164 arg1Of regulation,necroptotic
R4214 T6165 T6166 arg1Of regulation,of
R4215 T6167 T6166 arg2Of Akt,of
R4216 T6169 T6154 arg1Of we,understand
R4217 T6169 T6171 arg1Of we,analyzed
R4218 T6171 T6152 modOf analyzed,To
R4219 T6171 T6168 arg1Of analyzed,","
R4220 T6171 T6170 arg1Of analyzed,next
R4221 T6174 T6171 arg2Of course,analyzed
R4222 T6174 T6172 arg1Of course,the
R4223 T6174 T6173 arg1Of course,time
R4224 T6174 T6175 arg1Of course,of
R4225 T6178 T6175 arg2Of changes,of
R4226 T6178 T6176 arg1Of changes,these
R4227 T6178 T6177 arg1Of changes,phosphorylation
R4228 T6178 T6179 arg1Of changes,under
R4229 T6182 T6179 arg2Of conditions,under
R4230 T6182 T6180 arg1Of conditions,serum
R4231 T6182 T6181 arg1Of conditions,free
R4232 T6183 T6184 arg1Of We,found
R4233 T6187 T6186 arg1Of addition,the
R4234 T6187 T6188 arg1Of addition,of
R4235 T6187 T6196 arg1Of addition,led
R4236 T6189 T6188 arg2Of bFGF,of
R4237 T6189 T6190 arg1Of bFGF,alone
R4238 T6189 T6192 arg1Of bFGF,in
R4239 T6190 T6191 arg1Of alone,or
R4240 T6192 T6191 arg2Of in,or
R4241 T6193 T6192 arg2Of combination,in
R4242 T6193 T6194 arg1Of combination,with
R4243 T6195 T6194 arg2Of zVAD.fmk,with
R4244 T6196 T6184 arg2Of led,found
R4245 T6196 T6185 arg1Of led,that
R4246 T6196 T6197 arg1Of led,to
R4247 T6196 T6221 arg1Of led,","
R4248 T6196 T6222 modOf led,reflecting
R4249 T6200 T6201 arg1Of rapid,and
R4250 T6202 T6201 arg2Of transient,and
R4251 T6203 T6197 arg2Of increase,to
R4252 T6203 T6198 arg1Of increase,a
R4253 T6203 T6199 arg1Of increase,substantial
R4254 T6203 T6200 arg1Of increase,rapid
R4255 T6203 T6202 arg1Of increase,transient
R4256 T6203 T6204 arg1Of increase,in
R4257 T6206 T6207 arg1Of Thr308,and
R4258 T6207 T6205 arg1Of and,both
R4259 T6208 T6207 arg2Of Ser473,and
R4260 T6209 T6206 arg1Of phosphorylation,Thr308
R4261 T6209 T6208 arg1Of phosphorylation,Ser473
R4262 T6209 T6210 arg1Of phosphorylation,of
R4263 T6209 T6214 arg1Of phosphorylation,as
R4264 T6211 T6210 arg2Of Akt,of
R4265 T6214 T6204 arg2Of as,in
R4266 T6214 T6212 arg1Of as,as
R4267 T6214 T6213 arg1Of as,well
R4268 T6215 T6216 arg1Of JNK,and
R4269 T6216 T6214 arg2Of and,as
R4270 T6216 T6218 arg1Of and,at
R4271 T6217 T6216 arg2Of c-Jun,and
R4272 T6220 T6218 arg2Of minutes,at
R4273 T6220 T6219 arg1Of minutes,15
R4274 T6225 T6222 arg2Of response,reflecting
R4275 T6225 T6223 arg1Of response,the
R4276 T6225 T6224 arg1Of response,expected
R4277 T6225 T6226 arg1Of response,to
R4278 T6229 T6226 arg2Of stimulation,to
R4279 T6229 T6227 arg1Of stimulation,growth
R4280 T6229 T6228 arg1Of stimulation,factor
R4281 T6229 T6230 arg1Of stimulation,(
R4282 T6232 T6230 arg2Of 3C,(
R4283 T6232 T6231 arg1Of 3C,Fig.
R4284 T6233 T6230 arg3Of ),(
R4285 T6236 T6237 arg1Of IGF/zVAD,","
R4286 T6236 T6238 arg1Of IGF/zVAD,which
R4287 T6236 T6240 arg1Of IGF/zVAD,promoted
R4288 T6236 T6248 arg1Of IGF/zVAD,produced
R4289 T6240 T6239 arg1Of promoted,also
R4290 T6240 T6243 arg1Of promoted,under
R4291 T6242 T6240 arg2Of death,promoted
R4292 T6242 T6241 arg1Of death,cell
R4293 T6246 T6243 arg2Of conditions,under
R4294 T6246 T6244 arg1Of conditions,serum
R4295 T6246 T6245 arg1Of conditions,free
R4296 T6248 T6234 arg1Of produced,Similarly
R4297 T6248 T6235 arg1Of produced,","
R4298 T6248 T6247 arg1Of produced,","
R4299 T6248 T6255 arg1Of produced,on
R4300 T6248 T6257 arg1Of produced,","
R4301 T6248 T6258 arg1Of produced,while
R4302 T6251 T6248 arg2Of increase,produced
R4303 T6251 T6249 arg1Of increase,a
R4304 T6251 T6250 arg2Of increase,delayed
R4305 T6251 T6252 arg1Of increase,in
R4306 T6254 T6252 arg2Of phosphorylation,in
R4307 T6254 T6253 arg1Of phosphorylation,Thr308
R4308 T6256 T6255 arg2Of Akt,on
R4309 T6259 T6260 arg1Of IGF,alone
R4310 T6259 T6261 arg1Of IGF,caused
R4311 T6261 T6258 arg2Of caused,while
R4312 T6261 T6262 arg1Of caused,solely
R4313 T6264 T6265 arg1Of early,","
R4314 T6266 T6265 arg2Of transient,","
R4315 T6267 T6261 arg2Of increase,caused
R4316 T6267 T6263 arg1Of increase,an
R4317 T6267 T6264 arg1Of increase,early
R4318 T6267 T6266 arg1Of increase,transient
R4319 T6267 T6268 arg1Of increase,in
R4320 T6269 T6268 arg2Of phosphorylation,in
R4321 T6269 T6270 arg1Of phosphorylation,(
R4322 T6272 T6270 arg2Of S3C,(
R4323 T6272 T6271 arg1Of S3C,Fig.
R4324 T6273 T6270 arg3Of ),(
R4325 T6274 T6275 arg1Of We,confirmed
R4326 T6274 T6286 arg1Of We,using
R4327 T6275 T6286 modOf confirmed,using
R4328 T6277 T6275 arg2Of kinetics,confirmed
R4329 T6277 T6276 arg1Of kinetics,the
R4330 T6277 T6278 arg1Of kinetics,of
R4331 T6281 T6282 arg1Of Thr308,and
R4332 T6283 T6282 arg2Of Ser473,and
R4333 T6285 T6278 arg2Of changes,of
R4334 T6285 T6279 arg1Of changes,the
R4335 T6285 T6280 arg1Of changes,Akt
R4336 T6285 T6281 arg1Of changes,Thr308
R4337 T6285 T6283 arg1Of changes,Ser473
R4338 T6285 T6284 arg1Of changes,phosphorylation
R4339 T6290 T6286 arg2Of assay,using
R4340 T6290 T6287 arg1Of assay,a
R4341 T6290 T6288 arg1Of assay,quantitative
R4342 T6290 T6289 arg1Of assay,ELISA
R4343 T6290 T6291 arg1Of assay,","
R4344 T6290 T6292 arg1Of assay,which
R4345 T6290 T6294 arg1Of assay,showed
R4346 T6294 T6293 arg1Of showed,also
R4347 T6294 T6305 arg1Of showed,(
R4348 T6300 T6294 arg2Of increase,showed
R4349 T6300 T6295 arg1Of increase,a
R4350 T6300 T6296 arg1Of increase,robust
R4351 T6300 T6297 arg2Of increase,delayed
R4352 T6300 T6298 arg1Of increase,necroptosis-specific
R4353 T6300 T6299 arg1Of increase,RIP1-dependent
R4354 T6300 T6301 arg1Of increase,in
R4355 T6304 T6301 arg2Of phosphorylation,in
R4356 T6304 T6302 arg1Of phosphorylation,Akt
R4357 T6304 T6303 arg1Of phosphorylation,Thr308
R4358 T6307 T6305 arg2Of S3D,(
R4359 T6307 T6306 arg1Of S3D,Fig.
R4360 T6307 T6308 arg1Of S3D,","
R4361 T6309 T6308 arg2Of E,","
R4362 T6310 T6305 arg3Of ),(
R4363 T6311 T6312 arg1Of Taken,together
R4364 T6315 T6314 arg1Of results,these
R4365 T6315 T6316 arg1Of results,indicate
R4366 T6316 T6311 modOf indicate,Taken
R4367 T6316 T6313 arg1Of indicate,","
R4368 T6321 T6318 arg1Of increases,the
R4369 T6321 T6319 arg2Of increases,observed
R4370 T6321 T6320 arg2Of increases,delayed
R4371 T6321 T6322 arg1Of increases,in
R4372 T6321 T6327 arg1Of increases,","
R4373 T6321 T6335 arg1Of increases,represent
R4374 T6323 T6324 arg1Of Akt,and
R4375 T6325 T6324 arg2Of JNK,and
R4376 T6326 T6322 arg2Of phosphorylation,in
R4377 T6326 T6323 arg1Of phosphorylation,Akt
R4378 T6326 T6325 arg1Of phosphorylation,JNK
R4379 T6328 T6327 arg2Of preceding,","
R4380 T6330 T6328 arg2Of onset,preceding
R4381 T6330 T6329 arg1Of onset,the
R4382 T6330 T6331 arg1Of onset,of
R4383 T6333 T6331 arg2Of death,of
R4384 T6333 T6332 arg1Of death,cell
R4385 T6335 T6316 arg2Of represent,indicate
R4386 T6335 T6317 arg1Of represent,that
R4387 T6335 T6334 arg1Of represent,","
R4388 T6335 T6342 arg1Of represent,from
R4389 T6337 T6335 arg2Of consequences,represent
R4390 T6337 T6336 arg1Of consequences,specific
R4391 T6337 T6338 arg1Of consequences,of
R4392 T6337 T6341 arg1Of consequences,downstream
R4393 T6340 T6338 arg2Of signaling,of
R4394 T6340 T6339 arg1Of signaling,necroptotic
R4395 T6344 T6342 arg2Of kinase,from
R4396 T6344 T6343 arg1Of kinase,RIP1

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T5400 2031-2035 Protein denotes RIP1
T5399 1747-1751 Protein denotes RIP1
T5398 1323-1327 Protein denotes RIP1
T5397 1179-1183 Protein denotes bFGF
T5396 1084-1088 Protein denotes bFGF
T5395 1075-1079 Protein denotes bFGF
T5394 1035-1040 Protein denotes c-Jun
T5393 763-767 Protein denotes bFGF
T5392 740-744 Protein denotes bFGF
T5391 612-617 Protein denotes c-Jun
T5390 451-455 Protein denotes bFGF
T5389 280-284 Protein denotes RIP1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T6510 57-60 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6491 1894-1897 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6490 1774-1777 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6489 1611-1614 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6488 1483-1486 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6487 1266-1269 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6486 1023-1026 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6485 875-878 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6484 589-592 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6483 321-324 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6482 57-60 http://www.uniprot.org/uniprot/P31751 denotes Akt
T6435 2031-2035 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T6434 1747-1751 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T6433 1323-1327 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T6432 280-284 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T6526 1179-1183 http://www.uniprot.org/uniprot/Q788Q8 denotes bFGF
T6525 1084-1088 http://www.uniprot.org/uniprot/Q788Q8 denotes bFGF
T6524 1075-1079 http://www.uniprot.org/uniprot/Q788Q8 denotes bFGF
T6523 763-767 http://www.uniprot.org/uniprot/Q788Q8 denotes bFGF
T6522 740-744 http://www.uniprot.org/uniprot/Q788Q8 denotes bFGF
T6521 451-455 http://www.uniprot.org/uniprot/Q788Q8 denotes bFGF
T6519 1894-1897 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6518 1774-1777 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6517 1611-1614 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6516 1483-1486 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6515 1266-1269 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6514 1023-1026 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6513 875-878 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6512 589-592 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6511 321-324 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T6459 1266-1269 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6458 1023-1026 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6457 875-878 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6456 589-592 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6455 321-324 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6454 57-60 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6463 1894-1897 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6462 1774-1777 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6461 1611-1614 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6460 1483-1486 http://www.uniprot.org/uniprot/P31749 denotes Akt
T6539 1035-1040 http://www.uniprot.org/uniprot/P05412 denotes c-Jun
T6538 612-617 http://www.uniprot.org/uniprot/P05412 denotes c-Jun

UBERON-AE

Id Subject Object Predicate Lexical cue
T5279 1403-1408 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T5278 398-403 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

GO-BP

Id Subject Object Predicate Lexical cue
T5489 2005-2014 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T5488 1328-1343 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T5487 657-682 http://purl.obolibrary.org/obo/GO_1990089 denotes response to growth factor
T5486 657-682 http://purl.obolibrary.org/obo/GO_0071774 denotes response to growth factor
T5485 657-682 http://purl.obolibrary.org/obo/GO_0070848 denotes response to growth factor
T5484 657-682 http://purl.obolibrary.org/obo/GO_0035728 denotes response to growth factor
T5483 657-682 http://purl.obolibrary.org/obo/GO_0070849 denotes response to growth factor
T5482 307-317 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T5481 1906-1921 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5480 1785-1800 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5479 1633-1648 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5478 1550-1565 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5477 1464-1479 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5476 1041-1056 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5475 916-931 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5474 829-844 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5473 570-585 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5472 368-383 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5471 38-53 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5460 1902-1905 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5459 1274-1277 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5458 1031-1034 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5457 935-938 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5456 604-607 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5455 69-72 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5445 1946-1956 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T5444 1386-1396 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T5436 1951-1956 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T5435 1391-1396 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T5426 669-675 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T5425 261-267 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T5420 1726-1737 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T5419 1294-1305 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T5418 170-181 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T5410 1726-1737 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T5409 1294-1305 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T5408 170-181 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis

GO-MF

Id Subject Object Predicate Lexical cue
T5509 1328-1343 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T5508 1902-1905 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5507 1274-1277 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5506 1031-1034 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5505 935-938 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5504 604-607 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T5503 69-72 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK

GO-CC

Id Subject Object Predicate Lexical cue
T5518 1946-1950 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T5517 1386-1390 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

sentences

Id Subject Object Predicate Lexical cue
T5303 0-218 Sentence denotes Interestingly, we discovered that the phosphorylation of Akt Thr308, JNK and Jun are late events following zVAD.fmk stimulation (Fig. 3B) that coincide with the onset of necroptosis at 6 hr post-stimulation (Fig. S3A).
T5309 1816-2043 Sentence denotes Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase.
T5308 1578-1815 Sentence denotes We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E).
T5307 1345-1577 Sentence denotes Similarly, IGF/zVAD, which also promoted cell death under serum free conditions, produced a delayed increase in Thr308 phosphorylation on Akt, while IGF alone caused solely an early, transient increase in phosphorylation (Fig. S3C).
T5306 706-1344 Sentence denotes Significantly, the combination of bFGF/zVAD.fmk, but not bFGF alone, also caused a robust, second, delayed increase in the phosphorylation of Thr308, but not Ser473, of Akt as well as a delayed increase in the phosphorylation of JNK and Jun. Furthermore, Nec-1 had no significant effect on the early increase in both Akt and JNK/c-Jun phosphorylation triggered by both bFGF and bFGF/zVAD, while Nec-1, but not its inactive analog Nec-1i (Fig. S1E), efficiently blocked the bFGF/zVAD increase at 6–9 hr (Fig. 3D), suggesting that only the delayed activation of Akt and JNK is specific for necroptosis and dependent on RIP1 kinase activity.
T5305 421-705 Sentence denotes We found that the addition of bFGF alone or in combination with zVAD.fmk led to a substantial rapid and transient increase in both Thr308 and Ser473 phosphorylation of Akt as well as JNK and c-Jun at 15 minutes, reflecting the expected response to growth factor stimulation (Fig. 3C).
T5304 219-420 Sentence denotes To better understand the contributions of growth factors and RIP1 kinase to necroptotic regulation of Akt, we next analyzed the time course of these phosphorylation changes under serum free conditions.
T94 0-218 Sentence denotes Interestingly, we discovered that the phosphorylation of Akt Thr308, JNK and Jun are late events following zVAD.fmk stimulation (Fig. 3B) that coincide with the onset of necroptosis at 6 hr post-stimulation (Fig. S3A).
T95 219-420 Sentence denotes To better understand the contributions of growth factors and RIP1 kinase to necroptotic regulation of Akt, we next analyzed the time course of these phosphorylation changes under serum free conditions.
T96 421-705 Sentence denotes We found that the addition of bFGF alone or in combination with zVAD.fmk led to a substantial rapid and transient increase in both Thr308 and Ser473 phosphorylation of Akt as well as JNK and c-Jun at 15 minutes, reflecting the expected response to growth factor stimulation (Fig. 3C).
T97 706-947 Sentence denotes Significantly, the combination of bFGF/zVAD.fmk, but not bFGF alone, also caused a robust, second, delayed increase in the phosphorylation of Thr308, but not Ser473, of Akt as well as a delayed increase in the phosphorylation of JNK and Jun.
T98 948-1344 Sentence denotes Furthermore, Nec-1 had no significant effect on the early increase in both Akt and JNK/c-Jun phosphorylation triggered by both bFGF and bFGF/zVAD, while Nec-1, but not its inactive analog Nec-1i (Fig. S1E), efficiently blocked the bFGF/zVAD increase at 6–9 hr (Fig. 3D), suggesting that only the delayed activation of Akt and JNK is specific for necroptosis and dependent on RIP1 kinase activity.
T99 1345-1577 Sentence denotes Similarly, IGF/zVAD, which also promoted cell death under serum free conditions, produced a delayed increase in Thr308 phosphorylation on Akt, while IGF alone caused solely an early, transient increase in phosphorylation (Fig. S3C).
T100 1578-1815 Sentence denotes We confirmed the kinetics of the Akt Thr308 and Ser473 phosphorylation changes using a quantitative ELISA assay, which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation (Fig. S3D, E).
T101 1816-2043 Sentence denotes Taken together, these results indicate that the observed delayed increases in Akt and JNK phosphorylation, preceding the onset of cell death, represent specific consequences of necroptotic signaling downstream from RIP1 kinase.

simple1

Id Subject Object Predicate Lexical cue
T5553 2031-2035 Protein denotes RIP1
T5552 1747-1751 Protein denotes RIP1
T5551 1323-1327 Protein denotes RIP1
T5550 1179-1183 Protein denotes bFGF
T5549 1084-1088 Protein denotes bFGF
T5548 1075-1079 Protein denotes bFGF
T5547 1035-1040 Protein denotes c-Jun
T5546 763-767 Protein denotes bFGF
T5545 740-744 Protein denotes bFGF
T5544 612-617 Protein denotes c-Jun
T5543 451-455 Protein denotes bFGF
T5542 280-284 Protein denotes RIP1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T6428 1167-1174 Negative_regulation denotes blocked
T6427 1006-1014 Positive_regulation denotes increase
T6426 1310-1319 Positive_regulation denotes dependent
T6425 1189-1197 Positive_regulation denotes increase
T6424 1041-1056 Phosphorylation denotes phosphorylation
T6423 535-543 Positive_regulation denotes increase
T6412 2031-2035 Protein denotes RIP1
T6410 1323-1327 Protein denotes RIP1
T6409 1179-1183 Protein denotes bFGF
T6408 1084-1088 Protein denotes bFGF
T6407 1075-1079 Protein denotes bFGF
T6406 1035-1040 Protein denotes c-Jun
T6405 763-767 Protein denotes bFGF
T6404 740-744 Protein denotes bFGF
T6403 612-617 Protein denotes c-Jun
T6402 451-455 Protein denotes bFGF
T6401 280-284 Protein denotes RIP1
T6411 1747-1751 Protein denotes RIP1
R4411 T6403 T6423 themeOf c-Jun,increase
R4412 T6406 T6424 themeOf c-Jun,phosphorylation
R4413 T6409 T6425 themeOf bFGF,increase
R4414 T6410 T6426 themeOf RIP1,dependent
R4420 T6424 T6427 themeOf phosphorylation,increase
R4421 T6425 T6428 themeOf increase,blocked

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T6708 1189-1197 Positive_regulation denotes increase
T6707 1167-1174 Negative_regulation denotes blocked
T6693 2031-2035 Protein denotes RIP1
T6692 1747-1751 Protein denotes RIP1
T6691 1323-1327 Protein denotes RIP1
T6690 1179-1183 Protein denotes bFGF
T6689 1084-1088 Protein denotes bFGF
T6688 1075-1079 Protein denotes bFGF
T6687 1035-1040 Protein denotes c-Jun
T6686 763-767 Protein denotes bFGF
T6685 740-744 Protein denotes bFGF
T6684 612-617 Protein denotes c-Jun
T6683 451-455 Protein denotes bFGF
T6682 280-284 Protein denotes RIP1
R4491 T6690 T6708 themeOf bFGF,increase
R4498 T6708 T6707 themeOf increase,blocked

DLUT931

Id Subject Object Predicate Lexical cue
T6593 1167-1174 Negative_regulation denotes blocked
T6592 1189-1197 Positive_regulation denotes increase
T6591 1057-1066 Positive_regulation denotes triggered
T6590 1041-1056 Phosphorylation denotes phosphorylation
T6589 535-543 Positive_regulation denotes increase
T6588 439-447 Negative_regulation denotes addition
T6573 2031-2035 Protein denotes RIP1
T6572 1747-1751 Protein denotes RIP1
T6571 1323-1327 Protein denotes RIP1
T6570 1179-1183 Protein denotes bFGF
T6564 612-617 Protein denotes c-Jun
T6563 451-455 Protein denotes bFGF
T6562 280-284 Protein denotes RIP1
T6569 1084-1088 Protein denotes bFGF
T6568 1075-1079 Protein denotes bFGF
T6567 1035-1040 Protein denotes c-Jun
T6566 763-767 Protein denotes bFGF
T6565 740-744 Protein denotes bFGF
R4436 T6563 T6588 themeOf bFGF,addition
R4437 T6564 T6589 themeOf c-Jun,increase
R4438 T6567 T6590 themeOf c-Jun,phosphorylation
R4439 T6568 T6591 themeOf bFGF,triggered
R4440 T6569 T6591 causeOf bFGF,triggered
R4441 T6570 T6592 themeOf bFGF,increase
R4452 T6592 T6593 themeOf increase,blocked

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T7309 1902-1922 Phosphorylation denotes JNK phosphorylation,
T7308 34-89 Phosphorylation denotes the phosphorylation of Akt Thr308, JNK and Jun are late
T7304 295-324 Regulation denotes necroptotic regulation of Akt
T7300 1691-1800 Positive_regulation denotes which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation
T7295 1709-1800 Regulation denotes a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation
T7290 1435-1487 Negative_regulation denotes a delayed increase in Thr308 phosphorylation on Akt,
T7288 1771-1800 Phosphorylation denotes in Akt Thr308 phosphorylation
T7285 1240-1277 Positive_regulation denotes the delayed activation of Akt and JNK
T7284 1240-1277 Positive_regulation denotes the delayed activation of Akt and JNK
T7283 1709-1800 Negative_regulation denotes a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation
T7280 1435-1487 Positive_regulation denotes a delayed increase in Thr308 phosphorylation on Akt,
T7278 1240-1277 Negative_regulation denotes the delayed activation of Akt and JNK
T7277 1240-1277 Negative_regulation denotes the delayed activation of Akt and JNK
T7270 1457-1463 Entity denotes Thr308
T7266 1611-1614 Protein denotes Akt
T7261 280-284 Protein denotes RIP1
T7254 318-324 Protein denotes of Akt
T7248 552-558 Entity denotes Thr308
T7246 1310-1343 Protein denotes dependent on RIP1 kinase activity
T7244 448-455 Protein denotes of bFGF
T7243 1902-1905 Protein denotes JNK
T7242 1626-1632 Entity denotes Ser473
T7236 1774-1784 Entity denotes Akt Thr308
T7235 69-72 Protein denotes JNK
T7230 604-607 Protein denotes JNK
T7229 563-569 Entity denotes Ser473
T7227 1266-1269 Protein denotes Akt
T7222 1604-1621 Entity denotes of the Akt Thr308
T7212 1483-1487 Protein denotes Akt,
T7208 485-493 Entity denotes zVAD.fmk
T7206 1802-1805 Protein denotes Fig
T7205 1774-1777 Protein denotes Akt
T7192 1323-1327 Protein denotes RIP1
T7189 57-60 Protein denotes Akt
T7188 589-592 Protein denotes Akt
T7174 1274-1277 Protein denotes JNK
T7172 612-632 Protein denotes c-Jun at 15 minutes,
T7171 1488-1497 Protein denotes while IGF
T7168 2031-2042 Protein denotes RIP1 kinase
T7167 2031-2035 Protein denotes RIP1
T7164 1747-1761 Protein denotes RIP1-dependent
T7163 1943-1950 Entity denotes of cell
T7157 77-80 Protein denotes Jun
T7152 107-115 Entity denotes zVAD.fmk
T7149 1894-1897 Protein denotes Akt
T7148 280-291 Protein denotes RIP1 kinase
T7147 54-68 Entity denotes of Akt Thr308,
R4700 T7147 T7189 partOf "of Akt Thr308,",Akt
R4701 T7147 T7308 siteOf "of Akt Thr308,","the phosphorylation of Akt Thr308, JNK and Jun are late"
R4707 T7164 T7295 causeOf RIP1-dependent,a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation
R4714 T7174 T7285 themeOf JNK,the delayed activation of Akt and JNK
R4727 T7189 T7308 themeOf Akt,"the phosphorylation of Akt Thr308, JNK and Jun are late"
R4733 T7205 T7288 themeOf Akt,in Akt Thr308 phosphorylation
R4746 T7227 T7284 themeOf Akt,the delayed activation of Akt and JNK
R4749 T7236 T7205 partOf Akt Thr308,Akt
R4750 T7236 T7288 siteOf Akt Thr308,in Akt Thr308 phosphorylation
R4755 T7243 T7309 themeOf JNK,"JNK phosphorylation,"
R4760 T7254 T7304 themeOf of Akt,necroptotic regulation of Akt
R4770 T7280 T7290 themeOf "a delayed increase in Thr308 phosphorylation on Akt,","a delayed increase in Thr308 phosphorylation on Akt,"
R4772 T7284 T7277 themeOf the delayed activation of Akt and JNK,the delayed activation of Akt and JNK
R4773 T7285 T7278 themeOf the delayed activation of Akt and JNK,the delayed activation of Akt and JNK
R4775 T7288 T7300 themeOf in Akt Thr308 phosphorylation,which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation
R4776 T7300 T7283 themeOf which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation,a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation
R4777 T7300 T7295 themeOf which also showed a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation,a robust delayed necroptosis-specific RIP1-dependent increase in Akt Thr308 phosphorylation

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T6917 1633-1648 Phosphorylation denotes phosphorylation
T6916 1807-1810 Protein denotes S3D
T6915 1802-1805 Protein denotes Fig
T6914 1774-1777 Protein denotes Akt
T6913 1747-1751 Protein denotes RIP1
T6912 1611-1621 Protein denotes Akt Thr308
T6911 1538-1546 Positive_regulation denotes increase
T6910 1538-1546 Positive_regulation denotes increase
T6909 1445-1453 Positive_regulation denotes increase
T6908 1445-1453 Positive_regulation denotes increase
T6907 1550-1565 Phosphorylation denotes phosphorylation
T6906 1550-1565 Phosphorylation denotes phosphorylation
T6905 1464-1479 Phosphorylation denotes phosphorylation
T6904 1572-1575 Protein denotes S3C
T6903 1567-1570 Protein denotes Fig
T6902 1494-1497 Protein denotes IGF
T6901 1483-1486 Protein denotes Akt
T6900 1457-1463 Protein denotes Thr308
T6899 1360-1364 Protein denotes zVAD
T6898 1356-1359 Protein denotes IGF
T6897 1167-1174 Negative_regulation denotes blocked
T6896 1167-1174 Negative_regulation denotes blocked
T6895 1006-1014 Positive_regulation denotes increase
T6894 1006-1014 Positive_regulation denotes increase
T6893 1006-1014 Positive_regulation denotes increase
T6892 1252-1262 Positive_regulation denotes activation
T6891 1252-1262 Positive_regulation denotes activation
T6890 1189-1197 Positive_regulation denotes increase
T6889 1041-1056 Phosphorylation denotes phosphorylation
T6888 1041-1056 Phosphorylation denotes phosphorylation
T6887 1041-1056 Phosphorylation denotes phosphorylation
T6886 1006-1014 Positive_regulation denotes increase
T6885 1323-1334 Protein denotes RIP1 kinase
T6884 1274-1277 Protein denotes JNK
T6850 604-607 Protein denotes JNK
T6849 589-592 Protein denotes Akt
T6848 485-493 Protein denotes zVAD.fmk
T6847 451-455 Protein denotes bFGF
T6846 244-257 Regulation denotes contributions
T6845 307-317 Regulation denotes regulation
T6844 244-257 Regulation denotes contributions
T6843 321-324 Protein denotes Akt
T6842 280-291 Protein denotes RIP1 kinase
T6841 38-53 Phosphorylation denotes phosphorylation
T6840 38-53 Phosphorylation denotes phosphorylation
T6839 38-53 Phosphorylation denotes phosphorylation
T6838 213-216 Protein denotes S3A
T6837 208-211 Protein denotes Fig
T6836 112-115 Protein denotes fmk
T6835 77-80 Protein denotes Jun
T6834 69-72 Protein denotes JNK
T6833 57-67 Protein denotes Akt Thr308
T6883 1266-1269 Protein denotes Akt
T6882 1179-1188 Protein denotes bFGF/zVAD
T6881 1149-1152 Protein denotes S1E
T6880 1144-1147 Protein denotes Fig
T6879 1129-1142 Protein denotes analog Nec-1i
T6878 1101-1106 Protein denotes Nec-1
T6877 1089-1093 Protein denotes zVAD
T6876 1084-1088 Protein denotes bFGF
T6875 1075-1079 Protein denotes bFGF
T6874 1035-1040 Protein denotes c-Jun
T6873 1031-1034 Protein denotes JNK
T6872 1023-1026 Protein denotes Akt
T6871 961-966 Protein denotes Nec-1
T6870 900-908 Positive_regulation denotes increase
T6867 916-931 Phosphorylation denotes phosphorylation
T6866 916-931 Phosphorylation denotes phosphorylation
T6865 829-844 Phosphorylation denotes phosphorylation
T6864 943-946 Protein denotes Jun
T6863 935-938 Protein denotes JNK
T6862 875-878 Protein denotes Akt
T6861 763-767 Protein denotes bFGF
T6860 740-753 Protein denotes bFGF/zVAD.fmk
T6859 535-543 Positive_regulation denotes increase
T6858 535-543 Positive_regulation denotes increase
T6857 570-585 Phosphorylation denotes phosphorylation
T6856 570-585 Phosphorylation denotes phosphorylation
T6855 563-569 Entity denotes Ser473
T6854 552-558 Entity denotes Thr308
T6853 535-543 Positive_regulation denotes increase
T6852 439-447 Positive_regulation denotes addition
T6851 612-617 Protein denotes c-Jun
T6869 900-908 Positive_regulation denotes increase
T6868 813-821 Positive_regulation denotes increase
T6927 1881-1890 Positive_regulation denotes increases
T6926 1881-1890 Positive_regulation denotes increases
T6925 1906-1921 Phosphorylation denotes phosphorylation
T6924 1906-1921 Phosphorylation denotes phosphorylation
T6923 1881-1890 Positive_regulation denotes increases
T6922 2031-2042 Protein denotes RIP1 kinase
T6921 1902-1905 Protein denotes JNK
T6920 1894-1897 Protein denotes Akt
T6919 1762-1770 Positive_regulation denotes increase
T6918 1785-1800 Phosphorylation denotes phosphorylation
R4541 T6834 T6840 themeOf JNK,phosphorylation
R4543 T6835 T6841 themeOf Jun,phosphorylation
R4545 T6842 T6844 themeOf RIP1 kinase,contributions
R4547 T6843 T6845 themeOf Akt,regulation
R4549 T6845 T6846 themeOf regulation,contributions
R4550 T6847 T6852 themeOf bFGF,addition
R4552 T6849 T6856 themeOf Akt,phosphorylation
R4553 T6849 T6857 themeOf Akt,phosphorylation
R4554 T6849 T6854 partOf Akt,Thr308
R4555 T6849 T6855 partOf Akt,Ser473
R4556 T6850 T6853 themeOf JNK,increase
R4560 T6854 T6856 Site Thr308,phosphorylation
R4561 T6855 T6857 Site Ser473,phosphorylation
R4562 T6856 T6858 themeOf phosphorylation,increase
R4563 T6857 T6859 themeOf phosphorylation,increase
R4565 T6862 T6865 themeOf Akt,phosphorylation
R4567 T6863 T6866 themeOf JNK,phosphorylation
R4568 T6864 T6867 themeOf Jun,phosphorylation
R4569 T6865 T6868 themeOf phosphorylation,increase
R4571 T6866 T6869 themeOf phosphorylation,increase
R4572 T6867 T6870 themeOf phosphorylation,increase
R4574 T6871 T6886 causeOf Nec-1,increase
R4575 T6871 T6893 causeOf Nec-1,increase
R4576 T6871 T6894 causeOf Nec-1,increase
R4577 T6871 T6895 causeOf Nec-1,increase
R4578 T6872 T6886 themeOf Akt,increase
R4579 T6872 T6887 themeOf Akt,phosphorylation
R4581 T6873 T6888 themeOf JNK,phosphorylation
R4584 T6874 T6889 themeOf c-Jun,phosphorylation
R4586 T6878 T6896 causeOf Nec-1,blocked
R4588 T6879 T6897 causeOf analog Nec-1i,blocked
R4590 T6882 T6890 themeOf bFGF/zVAD,increase
R4592 T6883 T6891 themeOf Akt,activation
R4594 T6884 T6892 themeOf JNK,activation
R4596 T6833 T6839 themeOf Akt Thr308,phosphorylation
R4597 T6887 T6893 themeOf phosphorylation,increase
R4598 T6888 T6894 themeOf phosphorylation,increase
R4599 T6889 T6895 themeOf phosphorylation,increase
R4600 T6890 T6896 themeOf increase,blocked
R4601 T6890 T6897 themeOf increase,blocked
R4602 T6918 T6919 themeOf phosphorylation,increase
R4603 T6920 T6923 themeOf Akt,increases
R4604 T6898 T6908 causeOf IGF,increase
R4605 T6920 T6924 themeOf Akt,phosphorylation
R4606 T6900 T6905 themeOf Thr308,phosphorylation
R4607 T6901 T6909 causeOf Akt,increase
R4608 T6921 T6925 themeOf JNK,phosphorylation
R4609 T6903 T6906 themeOf Fig,phosphorylation
R4610 T6904 T6907 themeOf S3C,phosphorylation
R4611 T6905 T6908 themeOf phosphorylation,increase
R4612 T6905 T6909 themeOf phosphorylation,increase
R4613 T6906 T6910 themeOf phosphorylation,increase
R4614 T6924 T6926 themeOf phosphorylation,increases
R4615 T6907 T6911 themeOf phosphorylation,increase
R4616 T6925 T6927 themeOf phosphorylation,increases
R4617 T6912 T6917 themeOf Akt Thr308,phosphorylation
R4618 T6913 T6919 causeOf RIP1,increase
R4620 T6914 T6918 themeOf Akt,phosphorylation

test3

Id Subject Object Predicate Lexical cue
T5276 2031-2035 Protein denotes RIP1
T5275 1881-1890 Positive_regulation denotes increases
T5274 1785-1800 Phosphorylation denotes phosphorylation
T5273 1762-1770 Positive_regulation denotes increase
T5272 1752-1761 Regulation denotes dependent
T5271 1747-1751 Protein denotes RIP1
T5270 1550-1565 Phosphorylation denotes phosphorylation
T5269 1538-1546 Positive_regulation denotes increase
T5268 1464-1479 Phosphorylation denotes phosphorylation
T5267 1445-1453 Positive_regulation denotes increase
T5266 1323-1327 Protein denotes RIP1
T5265 1252-1262 Positive_regulation denotes activation
T5264 1189-1197 Positive_regulation denotes increase
T5263 1179-1183 Protein denotes bFGF
T5262 1084-1088 Protein denotes bFGF
T5261 1075-1079 Protein denotes bFGF
T5260 1057-1066 Positive_regulation denotes triggered
T5259 1041-1056 Phosphorylation denotes phosphorylation
T5258 1035-1040 Protein denotes c-Jun
T5257 1006-1014 Positive_regulation denotes increase
T5256 986-992 Regulation denotes effect
T5255 900-908 Positive_regulation denotes increase
T5254 829-844 Phosphorylation denotes phosphorylation
T5253 813-821 Positive_regulation denotes increase
T5252 763-767 Protein denotes bFGF
T5251 740-744 Protein denotes bFGF
T5250 612-617 Protein denotes c-Jun
T5249 570-585 Phosphorylation denotes phosphorylation
T5248 535-543 Positive_regulation denotes increase
T5247 451-455 Protein denotes bFGF
T5246 368-383 Phosphorylation denotes phosphorylation
T5245 307-317 Regulation denotes regulation
T5244 280-284 Protein denotes RIP1
T5243 97-106 Positive_regulation denotes following
T5242 38-53 Phosphorylation denotes phosphorylation
T5185 2031-2035 Protein denotes RIP1
T5184 1747-1751 Protein denotes RIP1
T5183 1323-1327 Protein denotes RIP1
T5182 1179-1183 Protein denotes bFGF
T5181 1084-1088 Protein denotes bFGF
T5180 1075-1079 Protein denotes bFGF
T5179 1035-1040 Protein denotes c-Jun
T5178 763-767 Protein denotes bFGF
T5177 740-744 Protein denotes bFGF
T5176 612-617 Protein denotes c-Jun
T5175 451-455 Protein denotes bFGF
T5174 280-284 Protein denotes RIP1
R3564 T5242 T5243 themeOf phosphorylation,following
R3565 T5249 T5248 themeOf phosphorylation,increase
R3566 T5250 T5249 themeOf c-Jun,phosphorylation
R3567 T5252 T5253 causeOf bFGF,increase
R3568 T5254 T5253 themeOf phosphorylation,increase
R3569 T5258 T5259 themeOf c-Jun,phosphorylation
R3570 T5259 T5257 themeOf phosphorylation,increase
R3571 T5260 T5257 themeOf triggered,increase
R3572 T5261 T5260 causeOf bFGF,triggered
R3573 T5262 T5260 causeOf bFGF,triggered
R3574 T5263 T5264 causeOf bFGF,increase
R3575 T5268 T5267 themeOf phosphorylation,increase
R3576 T5270 T5269 themeOf phosphorylation,increase
R3577 T5271 T5272 causeOf RIP1,dependent
R3578 T5273 T5272 themeOf increase,dependent
R3579 T5274 T5273 themeOf phosphorylation,increase