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PMC:3585731 / 143-1351 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T28 1011-1021 Gene_expression denotes production
T27 867-877 Gene_expression denotes production
T26 539-554 Phosphorylation denotes phosphorylation
T25 509-518 Regulation denotes dependent
T24 489-498 Positive_regulation denotes activated
T23 450-460 Gene_expression denotes production
T22 437-441 Regulation denotes role
T20 1006-1010 Protein denotes TNFα
T19 881-885 Protein denotes TNFα
T18 830-834 Protein denotes RIP1
T17 664-668 Protein denotes RIP1
T16 504-508 Protein denotes RIP1
T15 445-449 Protein denotes TNFα
T14 332-336 Protein denotes RIP1
T13 300-330 Protein denotes receptor interacting protein-1
R3 T19 T27 themeOf TNFα,production
R4 T20 T28 themeOf TNFα,production
R5 T23 T22 themeOf production,role
R1 T14 T13 equivalentTo RIP1,receptor interacting protein-1
R2 T15 T23 themeOf TNFα,production

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T352 1197-1207 NN denotes regulation
T351 1184-1196 JJ denotes inflammatory
T350 1180-1183 CC denotes and
T349 1174-1179 NN denotes death
T348 1169-1173 NN denotes cell
T347 1164-1168 DT denotes both
T346 1161-1163 IN denotes in
T345 1154-1160 NN denotes kinase
T344 1150-1153 NN denotes Akt
T343 1147-1149 IN denotes of
T342 1142-1146 NN denotes role
T341 1138-1141 DT denotes the
T340 1134-1137 CC denotes and
T339 1122-1133 NN denotes necroptosis
T338 1119-1121 IN denotes of
T337 1109-1118 NN denotes mechanism
T336 1105-1108 DT denotes the
T335 1100-1104 IN denotes into
T334 1091-1099 NN denotes insights
T333 1087-1090 JJ denotes new
T332 1079-1086 VB denotes provide
T331 1071-1078 NN denotes results
T330 1067-1070 PRP-DOLLAR- denotes our
T329 1065-1066 -COMMA- denotes ,
T328 1058-1065 RB denotes Overall
T327 1051-1056 NN denotes death
T326 1046-1050 NN denotes cell
T325 1043-1045 TO denotes to
T324 1030-1042 VB denotes contributing
T323 1022-1029 IN denotes without
T322 1011-1021 NN denotes production
T321 1006-1010 NN denotes TNFα
T320 983-1005 JJ denotes necroptosis-associated
T319 978-982 IN denotes over
T318 970-977 NN denotes control
T317 960-969 VB denotes exhibited
T316 956-959 NN denotes Akt
T315 954-955 -COMMA- denotes ,
T314 943-954 NN denotes macrophages
T313 939-942 CC denotes and
T312 927-938 NN denotes fibroblasts
T311 922-926 NN denotes lung
T310 916-921 NN denotes mouse
T309 913-915 IN denotes as
T308 908-912 JJ denotes such
T307 906-907 -COMMA- denotes ,
T306 901-906 NN denotes types
T305 896-900 NN denotes cell
T304 890-895 JJ denotes other
T303 887-889 IN denotes In
T302 881-885 NN denotes TNFα
T301 878-880 IN denotes of
T300 867-877 NN denotes production
T299 857-866 JJ denotes autocrine
T298 853-856 CC denotes and
T297 842-852 NN denotes activation
T296 838-841 NN denotes JNK
T295 835-837 TO denotes to
T294 830-834 NN denotes RIP1
T293 824-829 VB denotes links
T292 822-823 -COMMA- denotes ,
T291 816-822 NN denotes mTORC1
T290 808-815 IN denotes through
T289 803-807 NN denotes part
T288 800-802 IN denotes in
T287 791-799 VB denotes mediated
T286 789-790 -COMMA- denotes ,
T285 781-789 NN denotes activity
T284 777-780 NN denotes Akt
T283 774-775 -RRB- denotes )
T282 768-774 NN denotes mTORC1
T281 767-768 -LRB- denotes (
T280 765-766 CD denotes 1
T279 757-764 NN denotes complex
T278 747-756 NN denotes Rapamycin
T277 744-746 IN denotes of
T276 737-743 NN denotes Target
T275 727-736 JJ denotes mammalian
T274 724-726 IN denotes of
T273 714-723 NN denotes targeting
T272 703-713 JJ denotes downstream
T271 695-702 IN denotes through
T270 683-694 NN denotes necroptosis
T269 674-682 VB denotes controls
T268 670-673 NN denotes Akt
T267 664-668 NN denotes RIP1
T266 660-663 CC denotes and
T265 652-659 NN denotes factors
T264 645-651 NN denotes growth
T263 640-644 DT denotes both
T262 635-639 IN denotes from
T261 628-634 NN denotes inputs
T260 618-627 NN denotes signaling
T259 606-617 JJ denotes independent
T258 597-605 VB denotes requires
T257 586-596 NN denotes activation
T256 581-585 DT denotes this
T255 579-580 -COMMA- denotes ,
T254 574-579 NN denotes cells
T253 569-573 NN denotes L929
T252 566-568 IN denotes In
T251 558-564 NN denotes Thr308
T250 555-557 IN denotes on
T249 539-554 NN denotes phosphorylation
T248 535-538 PRP-DOLLAR- denotes its
T247 527-534 IN denotes through
T246 519-526 NN denotes fashion
T245 509-518 JJ denotes dependent
T244 504-508 NN denotes RIP1
T243 502-503 DT denotes a
T242 499-501 IN denotes in
T241 489-498 VB denotes activated
T240 486-488 VB denotes is
T239 482-485 NN denotes Akt
T238 480-481 -COMMA- denotes ,
T237 469-480 NN denotes necroptosis
T236 462-468 IN denotes During
T235 450-460 NN denotes production
T234 445-449 NN denotes TNFα
T233 442-444 IN denotes in
T232 437-441 NN denotes role
T231 433-436 JJ denotes key
T230 431-432 DT denotes a
T229 425-430 VB denotes plays
T228 421-424 CC denotes and
T227 415-420 NN denotes cells
T226 410-414 NN denotes L929
T225 407-409 IN denotes in
T224 395-406 NN denotes necroptosis
T223 391-394 IN denotes for
T222 382-390 JJ denotes critical
T221 379-381 VB denotes is
T220 370-378 NN denotes activity
T219 363-369 NN denotes kinase
T218 359-362 NN denotes Akt
T217 354-358 IN denotes that
T216 349-353 VB denotes show
T215 346-348 PRP denotes We
T214 338-344 NN denotes kinase
T213 336-337 -RRB- denotes )
T212 332-336 NN denotes RIP1
T211 331-332 -LRB- denotes (
T210 321-330 NN denotes protein-1
T209 309-320 NN denotes interacting
T208 300-308 NN denotes receptor
T207 291-299 NN denotes mediator
T206 279-290 NN denotes necroptosis
T205 275-278 DT denotes the
T204 272-274 IN denotes by
T203 261-271 VB denotes controlled
T202 250-260 NN denotes mechanisms
T201 240-249 NN denotes signaling
T200 236-239 DT denotes the
T199 223-235 VB denotes investigated
T198 220-222 PRP denotes we
T197 218-219 -COMMA- denotes ,
T196 214-218 NN denotes work
T195 209-213 DT denotes this
T194 206-208 IN denotes In
T193 203-204 -RRB- denotes )
T192 199-203 NN denotes SIRS
T191 198-199 -LRB- denotes (
T190 189-197 NN denotes syndrome
T189 180-188 NN denotes response
T188 167-179 JJ denotes inflammatory
T187 158-166 JJ denotes systemic
T186 154-157 CC denotes and
T185 141-153 NN denotes inflammation
T184 130-140 JJ denotes intestinal
T183 120-129 VB denotes including
T182 111-119 NN denotes diseases
T181 103-110 JJ denotes various
T180 100-102 IN denotes of
T179 87-99 NN denotes pathogenesis
T178 83-86 DT denotes the
T177 80-82 IN denotes in
T176 69-79 VB denotes implicated
T175 64-68 VB denotes been
T174 60-63 VB denotes has
T173 55-59 WDT denotes that
T172 49-54 NN denotes death
T171 44-48 NN denotes cell
T170 35-43 JJ denotes necrotic
T169 32-34 IN denotes of
T168 27-31 NN denotes form
T167 17-26 VB denotes regulated
T166 15-16 DT denotes a
T165 12-14 VB denotes is
T164 0-11 NN denotes Necroptosis
R25 T164 T165 arg1Of Necroptosis,is
R26 T168 T165 arg2Of form,is
R27 T168 T166 arg1Of form,a
R28 T168 T167 arg2Of form,regulated
R29 T168 T169 arg1Of form,of
R30 T168 T173 arg1Of form,that
R31 T168 T174 arg1Of form,has
R32 T168 T175 arg1Of form,been
R33 T168 T176 arg2Of form,implicated
R34 T172 T169 arg2Of death,of
R35 T172 T170 arg1Of death,necrotic
R36 T172 T171 arg1Of death,cell
R37 T176 T174 arg2Of implicated,has
R38 T176 T175 arg2Of implicated,been
R39 T176 T177 arg1Of implicated,in
R40 T179 T177 arg2Of pathogenesis,in
R41 T179 T178 arg1Of pathogenesis,the
R42 T179 T180 arg1Of pathogenesis,of
R43 T182 T180 arg2Of diseases,of
R44 T182 T181 arg1Of diseases,various
R45 T182 T183 arg1Of diseases,including
R46 T185 T184 arg1Of inflammation,intestinal
R47 T185 T186 arg1Of inflammation,and
R48 T186 T183 arg2Of and,including
R49 T190 T186 arg2Of syndrome,and
R50 T190 T187 arg1Of syndrome,systemic
R51 T190 T188 arg1Of syndrome,inflammatory
R52 T190 T189 arg1Of syndrome,response
R53 T190 T191 arg1Of syndrome,(
R54 T192 T191 arg2Of SIRS,(
R55 T193 T191 arg3Of ),(
R56 T196 T194 arg2Of work,In
R57 T196 T195 arg1Of work,this
R58 T198 T199 arg1Of we,investigated
R59 T199 T194 arg1Of investigated,In
R60 T199 T197 arg1Of investigated,","
R61 T202 T199 arg2Of mechanisms,investigated
R62 T202 T200 arg1Of mechanisms,the
R63 T202 T201 arg1Of mechanisms,signaling
R64 T202 T203 arg2Of mechanisms,controlled
R65 T212 T211 arg2Of RIP1,(
R66 T213 T211 arg3Of ),(
R67 T214 T203 arg1Of kinase,controlled
R68 T214 T204 arg2Of kinase,by
R69 T214 T205 arg1Of kinase,the
R70 T214 T206 arg1Of kinase,necroptosis
R71 T214 T207 arg1Of kinase,mediator
R72 T214 T208 arg1Of kinase,receptor
R73 T214 T209 arg1Of kinase,interacting
R74 T214 T210 arg1Of kinase,protein-1
R75 T214 T211 arg1Of kinase,(
R76 T215 T216 arg1Of We,show
R77 T220 T218 arg1Of activity,Akt
R78 T220 T219 arg1Of activity,kinase
R79 T220 T221 arg1Of activity,is
R80 T220 T222 arg1Of activity,critical
R81 T220 T229 arg1Of activity,plays
R82 T221 T225 arg1Of is,in
R83 T221 T228 arg1Of is,and
R84 T222 T221 arg2Of critical,is
R85 T222 T223 arg1Of critical,for
R86 T224 T223 arg2Of necroptosis,for
R87 T227 T225 arg2Of cells,in
R88 T227 T226 arg1Of cells,L929
R89 T228 T216 arg2Of and,show
R90 T228 T217 arg1Of and,that
R91 T229 T228 arg2Of plays,and
R92 T229 T233 arg1Of plays,in
R93 T232 T229 arg2Of role,plays
R94 T232 T230 arg1Of role,a
R95 T232 T231 arg1Of role,key
R96 T235 T233 arg2Of production,in
R97 T235 T234 arg1Of production,TNFα
R98 T237 T236 arg2Of necroptosis,During
R99 T239 T240 arg1Of Akt,is
R100 T239 T241 arg2Of Akt,activated
R101 T241 T236 arg1Of activated,During
R102 T241 T238 arg1Of activated,","
R103 T241 T240 arg2Of activated,is
R104 T241 T242 arg1Of activated,in
R105 T241 T247 arg1Of activated,through
R106 T245 T244 arg1Of dependent,RIP1
R107 T246 T242 arg2Of fashion,in
R108 T246 T243 arg1Of fashion,a
R109 T246 T245 arg1Of fashion,dependent
R110 T249 T247 arg2Of phosphorylation,through
R111 T249 T248 arg1Of phosphorylation,its
R112 T249 T250 arg1Of phosphorylation,on
R113 T251 T250 arg2Of Thr308,on
R114 T254 T252 arg2Of cells,In
R115 T254 T253 arg1Of cells,L929
R116 T257 T256 arg1Of activation,this
R117 T257 T258 arg1Of activation,requires
R118 T258 T252 arg1Of requires,In
R119 T258 T255 arg1Of requires,","
R120 T261 T258 arg2Of inputs,requires
R121 T261 T259 arg1Of inputs,independent
R122 T261 T260 arg1Of inputs,signaling
R123 T261 T262 arg1Of inputs,from
R124 T265 T264 arg1Of factors,growth
R125 T265 T266 arg1Of factors,and
R126 T266 T262 arg2Of and,from
R127 T266 T263 arg1Of and,both
R128 T267 T266 arg2Of RIP1,and
R129 T268 T269 arg1Of Akt,controls
R130 T269 T271 arg1Of controls,through
R131 T270 T269 arg2Of necroptosis,controls
R132 T273 T271 arg2Of targeting,through
R133 T273 T272 arg1Of targeting,downstream
R134 T273 T274 arg1Of targeting,of
R135 T276 T274 arg2Of Target,of
R136 T276 T275 arg1Of Target,mammalian
R137 T276 T277 arg1Of Target,of
R138 T279 T277 arg2Of complex,of
R139 T279 T278 arg1Of complex,Rapamycin
R140 T279 T280 arg1Of complex,1
R141 T279 T281 arg1Of complex,(
R142 T282 T281 arg2Of mTORC1,(
R143 T283 T281 arg3Of ),(
R144 T285 T284 arg1Of activity,Akt
R145 T285 T286 arg1Of activity,","
R146 T285 T287 arg2Of activity,mediated
R147 T285 T293 arg1Of activity,links
R148 T287 T288 arg1Of mediated,in
R149 T287 T290 arg1Of mediated,through
R150 T289 T288 arg2Of part,in
R151 T291 T290 arg2Of mTORC1,through
R152 T293 T292 arg1Of links,","
R153 T294 T293 arg2Of RIP1,links
R154 T294 T295 arg1Of RIP1,to
R155 T297 T296 arg1Of activation,JNK
R156 T297 T298 arg1Of activation,and
R157 T298 T295 arg2Of and,to
R158 T300 T298 arg2Of production,and
R159 T300 T299 arg1Of production,autocrine
R160 T300 T301 arg1Of production,of
R161 T302 T301 arg2Of TNFα,of
R162 T306 T303 arg2Of types,In
R163 T306 T304 arg1Of types,other
R164 T306 T305 arg1Of types,cell
R165 T306 T307 arg1Of types,","
R166 T306 T309 arg1Of types,as
R167 T309 T308 arg1Of as,such
R168 T312 T310 arg1Of fibroblasts,mouse
R169 T312 T311 arg1Of fibroblasts,lung
R170 T312 T313 arg1Of fibroblasts,and
R171 T313 T309 arg2Of and,as
R172 T314 T313 arg2Of macrophages,and
R173 T316 T317 arg1Of Akt,exhibited
R174 T316 T324 arg1Of Akt,contributing
R175 T317 T303 arg1Of exhibited,In
R176 T317 T315 arg1Of exhibited,","
R177 T317 T319 arg1Of exhibited,over
R178 T317 T323 arg1Of exhibited,without
R179 T318 T317 arg2Of control,exhibited
R180 T322 T319 arg2Of production,over
R181 T322 T320 arg1Of production,necroptosis-associated
R182 T322 T321 arg1Of production,TNFα
R183 T324 T323 arg2Of contributing,without
R184 T324 T325 arg1Of contributing,to
R185 T327 T325 arg2Of death,to
R186 T327 T326 arg1Of death,cell
R187 T331 T330 arg1Of results,our
R188 T331 T332 arg1Of results,provide
R189 T332 T328 arg1Of provide,Overall
R190 T332 T329 arg1Of provide,","
R191 T332 T346 arg1Of provide,in
R192 T334 T332 arg2Of insights,provide
R193 T334 T333 arg1Of insights,new
R194 T334 T335 arg1Of insights,into
R195 T337 T336 arg1Of mechanism,the
R196 T337 T338 arg1Of mechanism,of
R197 T337 T340 arg1Of mechanism,and
R198 T339 T338 arg2Of necroptosis,of
R199 T340 T335 arg2Of and,into
R200 T342 T340 arg2Of role,and
R201 T342 T341 arg1Of role,the
R202 T342 T343 arg1Of role,of
R203 T345 T343 arg2Of kinase,of
R204 T345 T344 arg1Of kinase,Akt
R205 T349 T348 arg1Of death,cell
R206 T349 T350 arg1Of death,and
R207 T350 T346 arg2Of and,in
R208 T350 T347 arg1Of and,both
R209 T352 T350 arg2Of regulation,and
R210 T352 T351 arg1Of regulation,inflammatory

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T94 664-668 Protein denotes RIP1
T95 830-834 Protein denotes RIP1
T96 881-885 Protein denotes TNFα
T97 1006-1010 Protein denotes TNFα
T90 300-330 Protein denotes receptor interacting protein-1
T91 332-336 Protein denotes RIP1
T92 445-449 Protein denotes TNFα
T93 504-508 Protein denotes RIP1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T409 830-834 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T408 664-668 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T407 504-508 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T406 332-336 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T404 1006-1010 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T403 881-885 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T402 445-449 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T400 1150-1153 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T399 956-959 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T398 777-780 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T397 670-673 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T396 482-485 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T395 359-362 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T393 1150-1153 http://www.uniprot.org/uniprot/P31751 denotes Akt
T392 956-959 http://www.uniprot.org/uniprot/P31751 denotes Akt
T391 777-780 http://www.uniprot.org/uniprot/P31751 denotes Akt
T390 670-673 http://www.uniprot.org/uniprot/P31751 denotes Akt
T389 482-485 http://www.uniprot.org/uniprot/P31751 denotes Akt
T388 359-362 http://www.uniprot.org/uniprot/P31751 denotes Akt
T381 359-362 http://www.uniprot.org/uniprot/P31749 denotes Akt
T382 482-485 http://www.uniprot.org/uniprot/P31749 denotes Akt
T383 670-673 http://www.uniprot.org/uniprot/P31749 denotes Akt
T384 777-780 http://www.uniprot.org/uniprot/P31749 denotes Akt
T385 956-959 http://www.uniprot.org/uniprot/P31749 denotes Akt
T386 1150-1153 http://www.uniprot.org/uniprot/P31749 denotes Akt

UBERON-AE

Id Subject Object Predicate Lexical cue
T59 922-926 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T58 130-140 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal

GO-BP

Id Subject Object Predicate Lexical cue
T134 1197-1207 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T133 838-841 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK
T132 645-651 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T131 574-596 http://purl.obolibrary.org/obo/GO_0001775 denotes cells, this activation
T130 539-554 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T129 363-378 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T128 618-627 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T127 240-249 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T126 167-188 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T125 141-153 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T124 87-99 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T123 1174-1179 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T122 1051-1056 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T121 49-54 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T120 1169-1179 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T119 1046-1056 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T118 44-54 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T117 35-54 http://purl.obolibrary.org/obo/GO_0097300 denotes necrotic cell death
T116 35-54 http://purl.obolibrary.org/obo/GO_0070265 denotes necrotic cell death
T115 35-54 http://purl.obolibrary.org/obo/GO_0010939 denotes necrotic cell death
T114 1122-1133 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T113 983-994 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T112 683-694 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T111 469-480 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T110 395-406 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T109 279-290 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T108 0-11 http://purl.obolibrary.org/obo/GO_0097528 denotes Necroptosis
T106 1122-1133 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T105 983-994 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T104 683-694 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T103 469-480 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T102 395-406 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T101 279-290 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T100 0-11 http://purl.obolibrary.org/obo/GO_0070266 denotes Necroptosis

GO-MF

Id Subject Object Predicate Lexical cue
T135 363-378 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T136 838-841 http://purl.obolibrary.org/obo/GO_0004705 denotes JNK

GO-CC

Id Subject Object Predicate Lexical cue
T142 816-822 http://purl.obolibrary.org/obo/GO_0031931 denotes mTORC1
T141 768-774 http://purl.obolibrary.org/obo/GO_0031931 denotes mTORC1
T140 1169-1173 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T139 1046-1050 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T138 896-900 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T137 44-48 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

sentences

Id Subject Object Predicate Lexical cue
T61 0-205 Sentence denotes Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS).
T62 206-345 Sentence denotes In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase.
T63 346-461 Sentence denotes We show that Akt kinase activity is critical for necroptosis in L929 cells and plays a key role in TNFα production.
T64 462-565 Sentence denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308.
T65 566-669 Sentence denotes In L929 cells, this activation requires independent signaling inputs from both growth factors and RIP1.
T66 670-776 Sentence denotes Akt controls necroptosis through downstream targeting of mammalian Target of Rapamycin complex 1 (mTORC1).
T67 777-886 Sentence denotes Akt activity, mediated in part through mTORC1, links RIP1 to JNK activation and autocrine production of TNFα.
T68 887-1057 Sentence denotes In other cell types, such as mouse lung fibroblasts and macrophages, Akt exhibited control over necroptosis-associated TNFα production without contributing to cell death.
T69 1058-1208 Sentence denotes Overall, our results provide new insights into the mechanism of necroptosis and the role of Akt kinase in both cell death and inflammatory regulation.
T4 0-205 Sentence denotes Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS).
T5 206-345 Sentence denotes In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase.
T6 346-461 Sentence denotes We show that Akt kinase activity is critical for necroptosis in L929 cells and plays a key role in TNFα production.
T7 462-565 Sentence denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308.
T8 566-669 Sentence denotes In L929 cells, this activation requires independent signaling inputs from both growth factors and RIP1.
T9 670-776 Sentence denotes Akt controls necroptosis through downstream targeting of mammalian Target of Rapamycin complex 1 (mTORC1).
T10 777-886 Sentence denotes Akt activity, mediated in part through mTORC1, links RIP1 to JNK activation and autocrine production of TNFα.
T11 887-1057 Sentence denotes In other cell types, such as mouse lung fibroblasts and macrophages, Akt exhibited control over necroptosis-associated TNFα production without contributing to cell death.
T12 1058-1208 Sentence denotes Overall, our results provide new insights into the mechanism of necroptosis and the role of Akt kinase in both cell death and inflammatory regulation.

simple1

Id Subject Object Predicate Lexical cue
T145 300-330 Protein denotes receptor interacting protein-1
T146 332-336 Protein denotes RIP1
T147 445-449 Protein denotes TNFα
T148 504-508 Protein denotes RIP1
T149 664-668 Protein denotes RIP1
T150 830-834 Protein denotes RIP1
T151 881-885 Protein denotes TNFα
T152 1006-1010 Protein denotes TNFα

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T355 300-330 Protein denotes receptor interacting protein-1
T356 332-336 Protein denotes RIP1
T357 445-449 Protein denotes TNFα
T358 504-508 Protein denotes RIP1
T359 664-668 Protein denotes RIP1
T360 830-834 Protein denotes RIP1
T361 881-885 Protein denotes TNFα
T362 1006-1010 Protein denotes TNFα
T366 437-441 Regulation denotes role
T367 450-460 Gene_expression denotes production
T368 824-829 Positive_regulation denotes links
T369 1011-1021 Gene_expression denotes production
R452 T357 T367 themeOf TNFα,production
R453 T360 T368 themeOf RIP1,links
R454 T362 T369 themeOf TNFα,production
R456 T367 T366 themeOf production,role

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T443 300-330 Protein denotes receptor interacting protein-1
T444 332-336 Protein denotes RIP1
T445 445-449 Protein denotes TNFα
T446 504-508 Protein denotes RIP1
T447 664-668 Protein denotes RIP1
T448 830-834 Protein denotes RIP1
T449 881-885 Protein denotes TNFα
T450 1006-1010 Protein denotes TNFα
T454 450-460 Gene_expression denotes production
T455 1011-1021 Gene_expression denotes production
R471 T445 T454 themeOf TNFα,production
R472 T450 T455 themeOf TNFα,production

DLUT931

Id Subject Object Predicate Lexical cue
T427 983-1005 Positive_regulation denotes necroptosis-associated
T426 1011-1021 Gene_expression denotes production
T425 597-605 Positive_regulation denotes requires
T424 437-441 Regulation denotes role
T412 300-330 Protein denotes receptor interacting protein-1
T413 332-336 Protein denotes RIP1
T414 445-449 Protein denotes TNFα
T415 504-508 Protein denotes RIP1
T416 664-668 Protein denotes RIP1
T417 830-834 Protein denotes RIP1
T418 881-885 Protein denotes TNFα
T419 1006-1010 Protein denotes TNFα
T423 450-460 Gene_expression denotes production
R211 T426 T427 themeOf production,necroptosis-associated
R459 T414 T423 themeOf TNFα,production
R460 T416 T425 themeOf RIP1,requires
R461 T419 T426 themeOf TNFα,production
R463 T423 T424 themeOf production,role

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T764 445-460 Gene_expression denotes TNFα production
T763 816-885 Binding denotes mTORC1, links RIP1 to JNK activation and autocrine production of TNFα
T762 838-852 Positive_regulation denotes JNK activation
T761 857-885 Gene_expression denotes autocrine production of TNFα
T760 566-668 Regulation denotes In L929 cells, this activation requires independent signaling inputs from both growth factors and RIP1
T759 983-1021 Gene_expression denotes necroptosis-associated TNFα production
T758 462-564 Phosphorylation denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308
T757 462-564 Positive_regulation denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308
T756 878-885 Protein denotes of TNFα
T755 943-955 Entity denotes macrophages,
T754 1147-1160 Protein denotes of Akt kinase
T752 830-834 Protein denotes RIP1
T751 816-822 Entity denotes mTORC1
T750 777-780 Protein denotes Akt
T749 956-959 Protein denotes Akt
T748 272-344 Protein denotes by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase
T747 1006-1010 Protein denotes TNFα
T746 332-336 Protein denotes RIP1
T745 504-518 Protein denotes RIP1 dependent
T743 359-362 Protein denotes Akt
T742 359-369 Protein denotes Akt kinase
T740 838-841 Protein denotes JNK
T739 890-938 Entity denotes other cell types, such as mouse lung fibroblasts
T738 768-774 Entity denotes mTORC1
T737 555-564 Entity denotes on Thr308
T736 300-337 Protein denotes receptor interacting protein-1 (RIP1)
T735 727-756 Protein denotes mammalian Target of Rapamycin
T734 445-449 Protein denotes TNFα
T733 670-673 Protein denotes Akt
T732 664-668 Protein denotes RIP1
T731 890-915 Entity denotes other cell types, such as
T730 757-775 Entity denotes complex 1 (mTORC1)
T729 482-485 Protein denotes Akt
T727 1150-1153 Protein denotes Akt
R433 T737 T758 siteOf on Thr308,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R434 T740 T762 themeOf JNK,JNK activation
R436 T747 T759 themeOf TNFα,necroptosis-associated TNFα production
R437 T751 T763 themeOf mTORC1,"mTORC1, links RIP1 to JNK activation and autocrine production of TNFα"
R438 T752 T763 themeOf RIP1,"mTORC1, links RIP1 to JNK activation and autocrine production of TNFα"
R439 T756 T761 themeOf of TNFα,autocrine production of TNFα
R429 T729 T757 themeOf Akt,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R430 T729 T758 themeOf Akt,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R431 T734 T764 themeOf TNFα,TNFα production
R432 T737 T729 partOf on Thr308,Akt

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T674 1079-1086 VB denotes provide
T673 1071-1078 NNS denotes results
T672 1067-1070 PRP$ denotes our
T671 1065-1066 , denotes ,
T670 1058-1065 RB denotes Overall
T669 1056-1057 . denotes .
T668 1051-1056 NN denotes death
T667 1046-1050 NN denotes cell
T666 1043-1045 TO denotes to
T665 1030-1042 VBG denotes contributing
T664 1022-1029 IN denotes without
T663 1011-1021 NN denotes production
T662 1006-1010 JJ denotes TNFα
T661 983-1005 JJ denotes necroptosis-associated
T660 978-982 IN denotes over
T659 970-977 NN denotes control
T658 960-969 VBD denotes exhibited
T657 956-959 NNP denotes Akt
T656 954-955 , denotes ,
T655 943-954 NNS denotes macrophages
T654 939-942 CC denotes and
T653 927-938 NNS denotes fibroblasts
T652 922-926 NN denotes lung
T651 916-921 NN denotes mouse
T650 913-915 IN denotes as
T649 908-912 JJ denotes such
T648 906-907 , denotes ,
T647 901-906 NNS denotes types
T646 896-900 NN denotes cell
T645 890-895 JJ denotes other
T644 887-889 IN denotes In
T643 885-886 . denotes .
T642 881-885 NNP denotes TNFα
T641 878-880 IN denotes of
T640 867-877 NN denotes production
T639 857-866 NN denotes autocrine
T638 853-856 CC denotes and
T637 842-852 NN denotes activation
T636 838-841 NNP denotes JNK
T635 835-837 TO denotes to
T634 830-834 VBP denotes RIP1
T633 824-829 NNS denotes links
T632 822-823 , denotes ,
T631 816-822 NNP denotes mTORC1
T630 808-815 IN denotes through
T629 803-807 NN denotes part
T628 800-802 IN denotes in
T627 791-799 VBN denotes mediated
T626 789-790 , denotes ,
T625 781-789 NN denotes activity
T624 777-780 JJ denotes Akt
T623 775-776 . denotes .
T622 774-775 -RRB- denotes )
T621 768-774 NN denotes mTORC1
T620 767-768 -LRB- denotes (
T619 765-766 CD denotes 1
T618 757-764 JJ denotes complex
T617 747-756 NNP denotes Rapamycin
T616 744-746 IN denotes of
T615 737-743 NNP denotes Target
T614 727-736 JJ denotes mammalian
T613 724-726 IN denotes of
T612 714-723 VBG denotes targeting
T611 703-713 JJ denotes downstream
T610 695-702 IN denotes through
T609 683-694 NN denotes necroptosis
T608 674-682 VBZ denotes controls
T607 670-673 NNP denotes Akt
T606 668-669 . denotes .
T605 664-668 NNP denotes RIP1
T604 660-663 CC denotes and
T603 652-659 NNS denotes factors
T602 645-651 NN denotes growth
T601 640-644 DT denotes both
T600 635-639 IN denotes from
T599 628-634 NNS denotes inputs
T598 618-627 VBG denotes signaling
T597 606-617 JJ denotes independent
T596 597-605 VBZ denotes requires
T595 586-596 NN denotes activation
T594 581-585 DT denotes this
T533 220-222 PRP denotes we
T532 218-219 , denotes ,
T531 214-218 NN denotes work
T530 209-213 DT denotes this
T529 206-208 IN denotes In
T528 204-205 . denotes .
T527 203-204 -RRB- denotes )
T526 199-203 NNP denotes SIRS
T525 198-199 -LRB- denotes (
T524 189-197 NN denotes syndrome
T523 180-188 NN denotes response
T522 167-179 JJ denotes inflammatory
T521 158-166 JJ denotes systemic
T520 154-157 CC denotes and
T519 141-153 NN denotes inflammation
T518 130-140 JJ denotes intestinal
T517 120-129 VBG denotes including
T516 111-119 NNS denotes diseases
T515 103-110 JJ denotes various
T514 100-102 IN denotes of
T513 87-99 NN denotes pathogenesis
T512 83-86 DT denotes the
T511 80-82 IN denotes in
T510 69-79 VBN denotes implicated
T509 64-68 VBN denotes been
T508 60-63 VBZ denotes has
T507 55-59 WDT denotes that
T506 49-54 NN denotes death
T505 44-48 NN denotes cell
T504 35-43 JJ denotes necrotic
T503 32-34 IN denotes of
T502 27-31 NN denotes form
T501 17-26 JJ denotes regulated
T500 15-16 DT denotes a
T499 12-14 VBZ denotes is
T498 0-11 NNP denotes Necroptosis
T573 462-468 IN denotes During
T572 460-461 . denotes .
T571 450-460 NN denotes production
T570 445-449 JJ denotes TNFα
T569 442-444 IN denotes in
T568 437-441 NN denotes role
T567 433-436 JJ denotes key
T566 431-432 DT denotes a
T565 425-430 VBZ denotes plays
T564 421-424 CC denotes and
T563 415-420 NNS denotes cells
T562 410-414 CD denotes L929
T561 407-409 IN denotes in
T560 395-406 NN denotes necroptosis
T559 391-394 IN denotes for
T558 382-390 JJ denotes critical
T557 379-381 VBZ denotes is
T556 370-378 NN denotes activity
T555 363-369 NN denotes kinase
T554 359-362 NNP denotes Akt
T553 354-358 IN denotes that
T552 349-353 VBP denotes show
T551 346-348 PRP denotes We
T550 344-345 . denotes .
T549 338-344 NN denotes kinase
T548 336-337 -RRB- denotes )
T547 332-336 CD denotes RIP1
T546 331-332 -LRB- denotes (
T545 321-330 NN denotes protein-1
T544 309-320 VBG denotes interacting
T543 300-308 NN denotes receptor
T542 291-299 NN denotes mediator
T541 279-290 NN denotes necroptosis
T540 275-278 DT denotes the
T539 272-274 IN denotes by
T538 261-271 VBN denotes controlled
T537 250-260 NNS denotes mechanisms
T536 240-249 VBG denotes signaling
T535 236-239 DT denotes the
T534 223-235 VBD denotes investigated
T593 579-580 , denotes ,
T592 574-579 NNS denotes cells
T591 569-573 CD denotes L929
T590 566-568 IN denotes In
T589 564-565 . denotes .
T588 558-564 NNP denotes Thr308
T587 555-557 IN denotes on
T586 539-554 NN denotes phosphorylation
T585 535-538 PRP$ denotes its
T584 527-534 IN denotes through
T583 519-526 NN denotes fashion
T582 509-518 JJ denotes dependent
T581 504-508 NNP denotes RIP1
T580 502-503 DT denotes a
T579 499-501 IN denotes in
T578 489-498 VBN denotes activated
T577 486-488 VBZ denotes is
T576 482-485 NNP denotes Akt
T575 480-481 , denotes ,
T574 469-480 NN denotes necroptosis
T694 1197-1207 NN denotes regulation
T695 1207-1208 . denotes .
T675 1087-1090 JJ denotes new
T676 1091-1099 NNS denotes insights
T677 1100-1104 IN denotes into
T678 1105-1108 DT denotes the
T679 1109-1118 NN denotes mechanism
T680 1119-1121 IN denotes of
T681 1122-1133 NN denotes necroptosis
T682 1134-1137 CC denotes and
T683 1138-1141 DT denotes the
T684 1142-1146 NN denotes role
T685 1147-1149 IN denotes of
T686 1150-1153 NNP denotes Akt
T687 1154-1160 NN denotes kinase
T688 1161-1163 IN denotes in
T689 1164-1168 DT denotes both
T690 1169-1173 NN denotes cell
T691 1174-1179 NN denotes death
T692 1180-1183 CC denotes and
T693 1184-1196 JJ denotes inflammatory
R240 T500 T502 det a,form
R241 T501 T502 amod regulated,form
R242 T502 T499 attr form,is
R243 T503 T502 prep of,form
R244 T504 T506 amod necrotic,death
R245 T505 T506 compound cell,death
R246 T506 T503 pobj death,of
R247 T507 T510 nsubjpass that,implicated
R248 T508 T510 aux has,implicated
R249 T509 T510 auxpass been,implicated
R250 T510 T506 relcl implicated,death
R251 T511 T510 prep in,implicated
R252 T512 T513 det the,pathogenesis
R253 T513 T511 pobj pathogenesis,in
R254 T514 T513 prep of,pathogenesis
R255 T515 T516 amod various,diseases
R256 T516 T514 pobj diseases,of
R257 T517 T516 prep including,diseases
R258 T518 T519 amod intestinal,inflammation
R259 T519 T517 pobj inflammation,including
R260 T520 T519 cc and,inflammation
R261 T521 T524 amod systemic,syndrome
R262 T522 T523 amod inflammatory,response
R263 T523 T524 compound response,syndrome
R264 T524 T519 conj syndrome,inflammation
R265 T525 T524 punct (,syndrome
R266 T526 T524 appos SIRS,syndrome
R267 T527 T524 punct ),syndrome
R269 T529 T534 prep In,investigated
R270 T530 T531 det this,work
R271 T531 T529 pobj work,In
R272 T532 T534 punct ",",investigated
R273 T533 T534 nsubj we,investigated
R274 T534 T534 ROOT investigated,investigated
R275 T535 T537 det the,mechanisms
R276 T536 T537 amod signaling,mechanisms
R277 T537 T534 dobj mechanisms,investigated
R278 T538 T537 acl controlled,mechanisms
R279 T539 T538 agent by,controlled
R280 T540 T543 det the,receptor
R281 T541 T542 amod necroptosis,mediator
R282 T542 T543 compound mediator,receptor
R283 T543 T539 pobj receptor,by
R284 T544 T543 acl interacting,receptor
R285 T545 T544 dobj protein-1,interacting
R286 T546 T545 punct (,protein-1
R287 T547 T545 appos RIP1,protein-1
R288 T548 T545 punct ),protein-1
R289 T549 T543 conj kinase,receptor
R290 T550 T534 punct .,investigated
R291 T551 T552 nsubj We,show
R292 T552 T552 ROOT show,show
R293 T553 T557 mark that,is
R294 T554 T556 compound Akt,activity
R295 T555 T556 compound kinase,activity
R296 T556 T557 nsubj activity,is
R297 T557 T552 ccomp is,show
R298 T558 T557 acomp critical,is
R299 T559 T558 prep for,critical
R300 T560 T559 pobj necroptosis,for
R301 T561 T557 prep in,is
R302 T562 T563 nummod L929,cells
R303 T563 T561 pobj cells,in
R304 T564 T557 cc and,is
R305 T565 T557 conj plays,is
R306 T566 T568 det a,role
R307 T567 T568 amod key,role
R308 T568 T565 dobj role,plays
R309 T569 T568 prep in,role
R310 T570 T571 amod TNFα,production
R311 T571 T569 pobj production,in
R312 T572 T552 punct .,show
R313 T573 T578 prep During,activated
R314 T574 T573 pobj necroptosis,During
R315 T575 T578 punct ",",activated
R316 T576 T578 nsubjpass Akt,activated
R317 T577 T578 auxpass is,activated
R318 T578 T578 ROOT activated,activated
R319 T579 T578 prep in,activated
R320 T580 T583 det a,fashion
R321 T581 T583 nmod RIP1,fashion
R322 T582 T583 amod dependent,fashion
R323 T583 T579 pobj fashion,in
R324 T584 T578 prep through,activated
R325 T585 T586 poss its,phosphorylation
R326 T586 T584 pobj phosphorylation,through
R327 T587 T586 prep on,phosphorylation
R328 T588 T587 pobj Thr308,on
R329 T589 T578 punct .,activated
R330 T590 T596 prep In,requires
R331 T591 T592 nummod L929,cells
R332 T592 T590 pobj cells,In
R333 T593 T596 punct ",",requires
R334 T594 T595 det this,activation
R335 T595 T596 nsubj activation,requires
R336 T596 T596 ROOT requires,requires
R337 T597 T599 amod independent,inputs
R338 T598 T599 amod signaling,inputs
R339 T599 T596 dobj inputs,requires
R340 T600 T599 prep from,inputs
R341 T601 T603 det both,factors
R342 T602 T603 compound growth,factors
R343 T603 T600 pobj factors,from
R344 T604 T603 cc and,factors
R345 T605 T603 conj RIP1,factors
R346 T606 T596 punct .,requires
R347 T607 T608 nsubj Akt,controls
R348 T608 T608 ROOT controls,controls
R349 T609 T608 dobj necroptosis,controls
R350 T610 T608 prep through,controls
R351 T611 T612 amod downstream,targeting
R352 T612 T610 pobj targeting,through
R353 T613 T612 prep of,targeting
R354 T614 T615 amod mammalian,Target
R355 T615 T613 pobj Target,of
R356 T616 T615 prep of,Target
R357 T617 T616 pobj Rapamycin,of
R358 T618 T621 nmod complex,mTORC1
R359 T619 T618 nummod 1,complex
R360 T620 T621 punct (,mTORC1
R361 T621 T612 conj mTORC1,targeting
R362 T622 T621 punct ),mTORC1
R363 T623 T608 punct .,controls
R364 T624 T625 amod Akt,activity
R365 T625 T625 ROOT activity,activity
R366 T626 T625 punct ",",activity
R367 T627 T625 acl mediated,activity
R368 T628 T627 prep in,mediated
R369 T629 T628 pobj part,in
R370 T630 T627 prep through,mediated
R371 T631 T630 pobj mTORC1,through
R372 T632 T634 punct ",",RIP1
R373 T633 T634 nsubj links,RIP1
R374 T634 T625 conj RIP1,activity
R375 T635 T634 prep to,RIP1
R376 T636 T637 compound JNK,activation
R377 T637 T640 nmod activation,production
R378 T638 T637 cc and,activation
R379 T639 T637 conj autocrine,activation
R380 T640 T635 pobj production,to
R381 T641 T640 prep of,production
R382 T642 T641 pobj TNFα,of
R383 T643 T634 punct .,RIP1
R384 T644 T658 prep In,exhibited
R385 T645 T647 amod other,types
R386 T646 T647 compound cell,types
R387 T647 T644 pobj types,In
R388 T648 T647 punct ",",types
R389 T649 T650 amod such,as
R390 T650 T647 prep as,types
R391 T651 T653 compound mouse,fibroblasts
R392 T652 T653 compound lung,fibroblasts
R393 T653 T650 pobj fibroblasts,as
R483 T684 T676 conj role,insights
R484 T685 T684 prep of,role
R485 T686 T687 compound Akt,kinase
R486 T687 T685 pobj kinase,of
R487 T688 T684 prep in,role
R488 T689 T691 det both,death
R489 T690 T691 compound cell,death
R490 T691 T688 pobj death,in
R491 T692 T691 cc and,death
R492 T693 T694 amod inflammatory,regulation
R493 T694 T691 conj regulation,death
R494 T695 T674 punct .,provide
R394 T654 T653 cc and,fibroblasts
R395 T655 T653 conj macrophages,fibroblasts
R396 T656 T658 punct ",",exhibited
R397 T657 T658 nsubj Akt,exhibited
R398 T658 T658 ROOT exhibited,exhibited
R399 T659 T658 dobj control,exhibited
R400 T660 T659 prep over,control
R401 T661 T663 amod necroptosis-associated,production
R402 T662 T663 compound TNFα,production
R403 T663 T660 pobj production,over
R404 T664 T658 prep without,exhibited
R405 T665 T664 pcomp contributing,without
R406 T666 T665 prep to,contributing
R407 T667 T668 compound cell,death
R408 T668 T666 pobj death,to
R409 T669 T658 punct .,exhibited
R410 T670 T674 advmod Overall,provide
R411 T671 T674 punct ",",provide
R412 T672 T673 poss our,results
R413 T673 T674 nsubj results,provide
R414 T674 T674 ROOT provide,provide
R474 T675 T676 amod new,insights
R475 T676 T674 dobj insights,provide
R476 T677 T676 prep into,insights
R477 T678 T679 det the,mechanism
R478 T679 T677 pobj mechanism,into
R479 T680 T679 prep of,mechanism
R480 T681 T680 pobj necroptosis,of
R481 T682 T676 cc and,insights
R482 T683 T684 det the,role

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T486 1197-1207 Regulation denotes regulation
T485 1150-1160 Protein denotes Akt kinase
T484 970-977 Regulation denotes control
T483 1011-1021 Gene_expression denotes production
T482 1006-1010 Protein denotes TNFα
T481 842-852 Positive_regulation denotes activation
T480 842-852 Positive_regulation denotes activation
T479 881-885 Protein denotes TNFα
T478 838-841 Protein denotes JNK
T477 830-834 Protein denotes RIP1
T476 777-780 Protein denotes Akt
T475 664-668 Protein denotes RIP1
T474 489-498 Positive_regulation denotes activated
T473 539-554 Phosphorylation denotes phosphorylation
T472 489-498 Positive_regulation denotes activated
T471 558-564 Protein denotes Thr308
T470 504-508 Protein denotes RIP1
T469 482-485 Protein denotes Akt
T468 450-460 Gene_expression denotes production
T467 445-449 Protein denotes TNFα
T466 359-369 Protein denotes Akt kinase
T465 261-271 Regulation denotes controlled
T464 261-271 Regulation denotes controlled
T463 332-336 Protein denotes RIP1
T462 291-330 Protein denotes mediator receptor interacting protein-1
R216 T462 T464 themeOf mediator receptor interacting protein-1,controlled
R217 T463 T465 themeOf RIP1,controlled
R218 T467 T468 themeOf TNFα,production
R219 T469 T472 themeOf Akt,activated
R220 T471 T473 themeOf Thr308,phosphorylation
R221 T473 T474 themeOf phosphorylation,activated
R222 T478 T480 themeOf JNK,activation
R223 T479 T481 themeOf TNFα,activation
R224 T482 T483 themeOf TNFα,production
R225 T483 T484 themeOf production,control
R226 T485 T486 themeOf Akt kinase,regulation

test3

Id Subject Object Predicate Lexical cue
T57 1011-1021 Gene_expression denotes production
T56 1006-1010 Protein denotes TNFα
T55 881-885 Protein denotes TNFα
T54 867-877 Gene_expression denotes production
T53 830-834 Protein denotes RIP1
T52 664-668 Protein denotes RIP1
T51 539-554 Phosphorylation denotes phosphorylation
T50 504-508 Protein denotes RIP1
T49 489-498 Positive_regulation denotes activated
T48 450-460 Gene_expression denotes production
T47 445-449 Protein denotes TNFα
T46 437-441 Regulation denotes role
T45 332-336 Protein denotes RIP1
T44 300-330 Protein denotes receptor interacting protein-1
T43 261-271 Regulation denotes controlled
T38 1006-1010 Protein denotes TNFα
T37 881-885 Protein denotes TNFα
T36 830-834 Protein denotes RIP1
T35 664-668 Protein denotes RIP1
T34 504-508 Protein denotes RIP1
T33 445-449 Protein denotes TNFα
T32 332-336 Protein denotes RIP1
T31 300-330 Protein denotes receptor interacting protein-1
R8 T44 T43 causeOf receptor interacting protein-1,controlled
R9 T45 T44 equivalentTo RIP1,receptor interacting protein-1
R10 T47 T48 themeOf TNFα,production
R11 T48 T46 themeOf production,role
R12 T50 T49 themeOf RIP1,activated
R13 T55 T54 themeOf TNFα,production
R14 T56 T57 themeOf TNFα,production