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PMC:3585731 / 0-934 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T11 14-18 Protein denotes TNFα
T12 43-47 Protein denotes RIP1
T21 4-13 Regulation denotes Regulates
T26 682-697 Phosphorylation denotes phosphorylation
T25 652-661 Regulation denotes dependent
T24 632-641 Positive_regulation denotes activated
T23 593-603 Gene_expression denotes production
T22 580-584 Regulation denotes role
T17 807-811 Protein denotes RIP1
T16 647-651 Protein denotes RIP1
T15 588-592 Protein denotes TNFα
T14 475-479 Protein denotes RIP1
T13 443-473 Protein denotes receptor interacting protein-1
R5 T23 T22 themeOf production,role
R1 T14 T13 equivalentTo RIP1,receptor interacting protein-1
R2 T15 T23 themeOf TNFα,production

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T153 0-3 NN denotes Akt
T154 4-13 VB denotes Regulates
T155 14-18 NNP denotes TNFα
T156 19-28 NNP denotes Synthesis
T157 29-39 NNP denotes Downstream
T158 40-42 IN denotes of
T159 43-47 NN denotes RIP1
T160 48-54 NN denotes Kinase
T161 55-65 NN denotes Activation
T162 66-72 IN denotes during
T163 73-84 NN denotes Necroptosis
T286 932-933 -COMMA- denotes ,
T285 924-932 NN denotes activity
T284 920-923 NN denotes Akt
T283 917-918 -RRB- denotes )
T282 911-917 NN denotes mTORC1
T281 910-911 -LRB- denotes (
T280 908-909 CD denotes 1
T279 900-907 NN denotes complex
T278 890-899 NN denotes Rapamycin
T277 887-889 IN denotes of
T276 880-886 NN denotes Target
T275 870-879 JJ denotes mammalian
T274 867-869 IN denotes of
T273 857-866 NN denotes targeting
T272 846-856 JJ denotes downstream
T271 838-845 IN denotes through
T270 826-837 NN denotes necroptosis
T269 817-825 VB denotes controls
T268 813-816 NN denotes Akt
T267 807-811 NN denotes RIP1
T266 803-806 CC denotes and
T265 795-802 NN denotes factors
T264 788-794 NN denotes growth
T263 783-787 DT denotes both
T262 778-782 IN denotes from
T261 771-777 NN denotes inputs
T260 761-770 NN denotes signaling
T259 749-760 JJ denotes independent
T258 740-748 VB denotes requires
T257 729-739 NN denotes activation
T256 724-728 DT denotes this
T255 722-723 -COMMA- denotes ,
T254 717-722 NN denotes cells
T253 712-716 NN denotes L929
T252 709-711 IN denotes In
T251 701-707 NN denotes Thr308
T250 698-700 IN denotes on
T249 682-697 NN denotes phosphorylation
T248 678-681 PRP-DOLLAR- denotes its
T247 670-677 IN denotes through
T246 662-669 NN denotes fashion
T245 652-661 JJ denotes dependent
T244 647-651 NN denotes RIP1
T243 645-646 DT denotes a
T242 642-644 IN denotes in
T241 632-641 VB denotes activated
T240 629-631 VB denotes is
T239 625-628 NN denotes Akt
T238 623-624 -COMMA- denotes ,
T237 612-623 NN denotes necroptosis
T236 605-611 IN denotes During
T235 593-603 NN denotes production
T234 588-592 NN denotes TNFα
T233 585-587 IN denotes in
T232 580-584 NN denotes role
T231 576-579 JJ denotes key
T230 574-575 DT denotes a
T229 568-573 VB denotes plays
T228 564-567 CC denotes and
T227 558-563 NN denotes cells
T226 553-557 NN denotes L929
T225 550-552 IN denotes in
T224 538-549 NN denotes necroptosis
T223 534-537 IN denotes for
T222 525-533 JJ denotes critical
T221 522-524 VB denotes is
T220 513-521 NN denotes activity
T219 506-512 NN denotes kinase
T218 502-505 NN denotes Akt
T217 497-501 IN denotes that
T216 492-496 VB denotes show
T215 489-491 PRP denotes We
T214 481-487 NN denotes kinase
T213 479-480 -RRB- denotes )
T212 475-479 NN denotes RIP1
T211 474-475 -LRB- denotes (
T210 464-473 NN denotes protein-1
T209 452-463 NN denotes interacting
T208 443-451 NN denotes receptor
T207 434-442 NN denotes mediator
T206 422-433 NN denotes necroptosis
T205 418-421 DT denotes the
T204 415-417 IN denotes by
T203 404-414 VB denotes controlled
T202 393-403 NN denotes mechanisms
T201 383-392 NN denotes signaling
T200 379-382 DT denotes the
T199 366-378 VB denotes investigated
T198 363-365 PRP denotes we
T197 361-362 -COMMA- denotes ,
T196 357-361 NN denotes work
T195 352-356 DT denotes this
T194 349-351 IN denotes In
T193 346-347 -RRB- denotes )
T192 342-346 NN denotes SIRS
T191 341-342 -LRB- denotes (
T190 332-340 NN denotes syndrome
T189 323-331 NN denotes response
T188 310-322 JJ denotes inflammatory
T187 301-309 JJ denotes systemic
T186 297-300 CC denotes and
T185 284-296 NN denotes inflammation
T184 273-283 JJ denotes intestinal
T183 263-272 VB denotes including
T182 254-262 NN denotes diseases
T181 246-253 JJ denotes various
T180 243-245 IN denotes of
T179 230-242 NN denotes pathogenesis
T178 226-229 DT denotes the
T177 223-225 IN denotes in
T176 212-222 VB denotes implicated
T175 207-211 VB denotes been
T174 203-206 VB denotes has
T173 198-202 WDT denotes that
T172 192-197 NN denotes death
T171 187-191 NN denotes cell
T170 178-186 JJ denotes necrotic
T169 175-177 IN denotes of
T168 170-174 NN denotes form
T167 160-169 VB denotes regulated
T166 158-159 DT denotes a
T165 155-157 VB denotes is
T164 143-154 NN denotes Necroptosis
R15 T153 T154 arg1Of Akt,Regulates
R16 T154 T162 arg1Of Regulates,during
R17 T157 T154 arg2Of Downstream,Regulates
R18 T157 T155 arg1Of Downstream,TNFα
R19 T157 T156 arg1Of Downstream,Synthesis
R20 T157 T158 arg1Of Downstream,of
R21 T161 T158 arg2Of Activation,of
R22 T161 T159 arg1Of Activation,RIP1
R23 T161 T160 arg1Of Activation,Kinase
R24 T163 T162 arg2Of Necroptosis,during
R25 T164 T165 arg1Of Necroptosis,is
R26 T168 T165 arg2Of form,is
R27 T168 T166 arg1Of form,a
R28 T168 T167 arg2Of form,regulated
R29 T168 T169 arg1Of form,of
R30 T168 T173 arg1Of form,that
R31 T168 T174 arg1Of form,has
R32 T168 T175 arg1Of form,been
R33 T168 T176 arg2Of form,implicated
R34 T172 T169 arg2Of death,of
R35 T172 T170 arg1Of death,necrotic
R36 T172 T171 arg1Of death,cell
R37 T176 T174 arg2Of implicated,has
R38 T176 T175 arg2Of implicated,been
R39 T176 T177 arg1Of implicated,in
R40 T179 T177 arg2Of pathogenesis,in
R41 T179 T178 arg1Of pathogenesis,the
R42 T179 T180 arg1Of pathogenesis,of
R43 T182 T180 arg2Of diseases,of
R44 T182 T181 arg1Of diseases,various
R45 T182 T183 arg1Of diseases,including
R46 T185 T184 arg1Of inflammation,intestinal
R47 T185 T186 arg1Of inflammation,and
R48 T186 T183 arg2Of and,including
R49 T190 T186 arg2Of syndrome,and
R50 T190 T187 arg1Of syndrome,systemic
R51 T190 T188 arg1Of syndrome,inflammatory
R52 T190 T189 arg1Of syndrome,response
R53 T190 T191 arg1Of syndrome,(
R54 T192 T191 arg2Of SIRS,(
R55 T193 T191 arg3Of ),(
R56 T196 T194 arg2Of work,In
R57 T196 T195 arg1Of work,this
R58 T198 T199 arg1Of we,investigated
R59 T199 T194 arg1Of investigated,In
R60 T199 T197 arg1Of investigated,","
R61 T202 T199 arg2Of mechanisms,investigated
R62 T202 T200 arg1Of mechanisms,the
R63 T202 T201 arg1Of mechanisms,signaling
R64 T202 T203 arg2Of mechanisms,controlled
R65 T212 T211 arg2Of RIP1,(
R66 T213 T211 arg3Of ),(
R67 T214 T203 arg1Of kinase,controlled
R68 T214 T204 arg2Of kinase,by
R69 T214 T205 arg1Of kinase,the
R70 T214 T206 arg1Of kinase,necroptosis
R71 T214 T207 arg1Of kinase,mediator
R72 T214 T208 arg1Of kinase,receptor
R73 T214 T209 arg1Of kinase,interacting
R74 T214 T210 arg1Of kinase,protein-1
R75 T214 T211 arg1Of kinase,(
R76 T215 T216 arg1Of We,show
R77 T220 T218 arg1Of activity,Akt
R78 T220 T219 arg1Of activity,kinase
R79 T220 T221 arg1Of activity,is
R80 T220 T222 arg1Of activity,critical
R81 T220 T229 arg1Of activity,plays
R82 T221 T225 arg1Of is,in
R83 T221 T228 arg1Of is,and
R84 T222 T221 arg2Of critical,is
R85 T222 T223 arg1Of critical,for
R86 T224 T223 arg2Of necroptosis,for
R87 T227 T225 arg2Of cells,in
R88 T227 T226 arg1Of cells,L929
R89 T228 T216 arg2Of and,show
R90 T228 T217 arg1Of and,that
R91 T229 T228 arg2Of plays,and
R92 T229 T233 arg1Of plays,in
R93 T232 T229 arg2Of role,plays
R94 T232 T230 arg1Of role,a
R95 T232 T231 arg1Of role,key
R96 T235 T233 arg2Of production,in
R97 T235 T234 arg1Of production,TNFα
R98 T237 T236 arg2Of necroptosis,During
R99 T239 T240 arg1Of Akt,is
R100 T239 T241 arg2Of Akt,activated
R101 T241 T236 arg1Of activated,During
R102 T241 T238 arg1Of activated,","
R103 T241 T240 arg2Of activated,is
R104 T241 T242 arg1Of activated,in
R105 T241 T247 arg1Of activated,through
R106 T245 T244 arg1Of dependent,RIP1
R107 T246 T242 arg2Of fashion,in
R108 T246 T243 arg1Of fashion,a
R109 T246 T245 arg1Of fashion,dependent
R110 T249 T247 arg2Of phosphorylation,through
R111 T249 T248 arg1Of phosphorylation,its
R112 T249 T250 arg1Of phosphorylation,on
R113 T251 T250 arg2Of Thr308,on
R114 T254 T252 arg2Of cells,In
R115 T254 T253 arg1Of cells,L929
R116 T257 T256 arg1Of activation,this
R117 T257 T258 arg1Of activation,requires
R118 T258 T252 arg1Of requires,In
R119 T258 T255 arg1Of requires,","
R120 T261 T258 arg2Of inputs,requires
R121 T261 T259 arg1Of inputs,independent
R122 T261 T260 arg1Of inputs,signaling
R123 T261 T262 arg1Of inputs,from
R124 T265 T264 arg1Of factors,growth
R125 T265 T266 arg1Of factors,and
R126 T266 T262 arg2Of and,from
R127 T266 T263 arg1Of and,both
R128 T267 T266 arg2Of RIP1,and
R129 T268 T269 arg1Of Akt,controls
R130 T269 T271 arg1Of controls,through
R131 T270 T269 arg2Of necroptosis,controls
R132 T273 T271 arg2Of targeting,through
R133 T273 T272 arg1Of targeting,downstream
R134 T273 T274 arg1Of targeting,of
R135 T276 T274 arg2Of Target,of
R136 T276 T275 arg1Of Target,mammalian
R137 T276 T277 arg1Of Target,of
R138 T279 T277 arg2Of complex,of
R139 T279 T278 arg1Of complex,Rapamycin
R140 T279 T280 arg1Of complex,1
R141 T279 T281 arg1Of complex,(
R142 T282 T281 arg2Of mTORC1,(
R143 T283 T281 arg3Of ),(
R144 T285 T284 arg1Of activity,Akt
R145 T285 T286 arg1Of activity,","

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T94 807-811 Protein denotes RIP1
T88 14-18 Protein denotes TNFα
T89 43-47 Protein denotes RIP1
T90 443-473 Protein denotes receptor interacting protein-1
T91 475-479 Protein denotes RIP1
T92 588-592 Protein denotes TNFα
T93 647-651 Protein denotes RIP1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T387 0-3 http://www.uniprot.org/uniprot/P31751 denotes Akt
T394 0-3 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T401 14-18 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T405 43-47 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T408 807-811 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T407 647-651 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T406 475-479 http://www.uniprot.org/uniprot/Q13546 denotes RIP1
T402 588-592 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T398 920-923 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T397 813-816 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T396 625-628 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T395 502-505 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T391 920-923 http://www.uniprot.org/uniprot/P31751 denotes Akt
T390 813-816 http://www.uniprot.org/uniprot/P31751 denotes Akt
T389 625-628 http://www.uniprot.org/uniprot/P31751 denotes Akt
T388 502-505 http://www.uniprot.org/uniprot/P31751 denotes Akt
T380 0-3 http://www.uniprot.org/uniprot/P31749 denotes Akt
T381 502-505 http://www.uniprot.org/uniprot/P31749 denotes Akt
T382 625-628 http://www.uniprot.org/uniprot/P31749 denotes Akt
T383 813-816 http://www.uniprot.org/uniprot/P31749 denotes Akt
T384 920-923 http://www.uniprot.org/uniprot/P31749 denotes Akt

UBERON-AE

Id Subject Object Predicate Lexical cue
T58 273-283 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal

GO-BP

Id Subject Object Predicate Lexical cue
T98 19-28 http://purl.obolibrary.org/obo/GO_0009058 denotes Synthesis
T99 73-84 http://purl.obolibrary.org/obo/GO_0070266 denotes Necroptosis
T107 73-84 http://purl.obolibrary.org/obo/GO_0097528 denotes Necroptosis
T132 788-794 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T131 717-739 http://purl.obolibrary.org/obo/GO_0001775 denotes cells, this activation
T130 682-697 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T129 506-521 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T128 761-770 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T127 383-392 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T126 310-331 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T125 284-296 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T124 230-242 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T121 192-197 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T118 187-197 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T117 178-197 http://purl.obolibrary.org/obo/GO_0097300 denotes necrotic cell death
T116 178-197 http://purl.obolibrary.org/obo/GO_0070265 denotes necrotic cell death
T115 178-197 http://purl.obolibrary.org/obo/GO_0010939 denotes necrotic cell death
T112 826-837 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T111 612-623 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T110 538-549 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T109 422-433 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T108 143-154 http://purl.obolibrary.org/obo/GO_0097528 denotes Necroptosis
T104 826-837 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T103 612-623 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T102 538-549 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T101 422-433 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T100 143-154 http://purl.obolibrary.org/obo/GO_0070266 denotes Necroptosis

GO-MF

Id Subject Object Predicate Lexical cue
T135 506-521 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity

GO-CC

Id Subject Object Predicate Lexical cue
T141 911-917 http://purl.obolibrary.org/obo/GO_0031931 denotes mTORC1
T137 187-191 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

sentences

Id Subject Object Predicate Lexical cue
T60 0-84 Sentence denotes Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis
T61 143-348 Sentence denotes Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS).
T62 349-488 Sentence denotes In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase.
T63 489-604 Sentence denotes We show that Akt kinase activity is critical for necroptosis in L929 cells and plays a key role in TNFα production.
T64 605-708 Sentence denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308.
T65 709-812 Sentence denotes In L929 cells, this activation requires independent signaling inputs from both growth factors and RIP1.
T66 813-919 Sentence denotes Akt controls necroptosis through downstream targeting of mammalian Target of Rapamycin complex 1 (mTORC1).
T1 0-84 Sentence denotes Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis
T2 85-132 Sentence denotes Interplay of Akt and JNK in Necroptosis Control
T3 134-142 Sentence denotes Abstract
T4 143-348 Sentence denotes Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS).
T5 349-488 Sentence denotes In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase.
T6 489-604 Sentence denotes We show that Akt kinase activity is critical for necroptosis in L929 cells and plays a key role in TNFα production.
T7 605-708 Sentence denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308.
T8 709-812 Sentence denotes In L929 cells, this activation requires independent signaling inputs from both growth factors and RIP1.
T9 813-919 Sentence denotes Akt controls necroptosis through downstream targeting of mammalian Target of Rapamycin complex 1 (mTORC1).

simple1

Id Subject Object Predicate Lexical cue
T145 443-473 Protein denotes receptor interacting protein-1
T146 475-479 Protein denotes RIP1
T147 588-592 Protein denotes TNFα
T148 647-651 Protein denotes RIP1
T149 807-811 Protein denotes RIP1
T143 14-18 Protein denotes TNFα
T144 43-47 Protein denotes RIP1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T353 14-18 Protein denotes TNFα
T354 43-47 Protein denotes RIP1
T363 4-13 Regulation denotes Regulates
T364 19-28 Gene_expression denotes Synthesis
T355 443-473 Protein denotes receptor interacting protein-1
T356 475-479 Protein denotes RIP1
T357 588-592 Protein denotes TNFα
T358 647-651 Protein denotes RIP1
T359 807-811 Protein denotes RIP1
T365 55-65 Positive_regulation denotes Activation
T366 580-584 Regulation denotes role
T367 593-603 Gene_expression denotes production
R450 T353 T364 themeOf TNFα,Synthesis
R451 T354 T365 themeOf RIP1,Activation
R452 T357 T367 themeOf TNFα,production
R455 T364 T363 themeOf Synthesis,Regulates
R456 T367 T366 themeOf production,role

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T441 14-18 Protein denotes TNFα
T442 43-47 Protein denotes RIP1
T451 19-28 Gene_expression denotes Synthesis
T452 4-13 Regulation denotes Regulates
T453 55-65 Positive_regulation denotes Activation
T443 443-473 Protein denotes receptor interacting protein-1
T444 475-479 Protein denotes RIP1
T445 588-592 Protein denotes TNFα
T446 647-651 Protein denotes RIP1
T447 807-811 Protein denotes RIP1
T454 593-603 Gene_expression denotes production
R469 T441 T451 themeOf TNFα,Synthesis
R470 T442 T453 themeOf RIP1,Activation
R471 T445 T454 themeOf TNFα,production
R473 T451 T452 themeOf Synthesis,Regulates

DLUT931

Id Subject Object Predicate Lexical cue
T425 740-748 Positive_regulation denotes requires
T424 580-584 Regulation denotes role
T410 14-18 Protein denotes TNFα
T411 43-47 Protein denotes RIP1
T420 19-28 Gene_expression denotes Synthesis
T421 55-65 Positive_regulation denotes Activation
T422 4-13 Regulation denotes Regulates
T412 443-473 Protein denotes receptor interacting protein-1
T413 475-479 Protein denotes RIP1
T414 588-592 Protein denotes TNFα
T415 647-651 Protein denotes RIP1
T416 807-811 Protein denotes RIP1
T423 593-603 Gene_expression denotes production
R457 T410 T420 themeOf TNFα,Synthesis
R458 T411 T421 themeOf RIP1,Activation
R459 T414 T423 themeOf TNFα,production
R460 T416 T425 themeOf RIP1,requires
R462 T420 T422 themeOf Synthesis,Regulates
R463 T423 T424 themeOf production,role

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T728 0-3 Protein denotes Akt
T741 43-54 Protein denotes RIP1 Kinase
T744 14-17 Protein denotes TNF
T753 43-47 Protein denotes RIP1
T765 43-84 Positive_regulation denotes RIP1 Kinase Activation during Necroptosis
T764 588-603 Gene_expression denotes TNFα production
T760 709-811 Regulation denotes In L929 cells, this activation requires independent signaling inputs from both growth factors and RIP1
T758 605-707 Phosphorylation denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308
T757 605-707 Positive_regulation denotes During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308
T750 920-923 Protein denotes Akt
T748 415-487 Protein denotes by the necroptosis mediator receptor interacting protein-1 (RIP1) kinase
T746 475-479 Protein denotes RIP1
T745 647-661 Protein denotes RIP1 dependent
T743 502-505 Protein denotes Akt
T742 502-512 Protein denotes Akt kinase
T738 911-917 Entity denotes mTORC1
T737 698-707 Entity denotes on Thr308
T736 443-480 Protein denotes receptor interacting protein-1 (RIP1)
T735 870-899 Protein denotes mammalian Target of Rapamycin
T734 588-592 Protein denotes TNFα
T733 813-816 Protein denotes Akt
T732 807-811 Protein denotes RIP1
T730 900-918 Entity denotes complex 1 (mTORC1)
T729 625-628 Protein denotes Akt
R433 T737 T758 siteOf on Thr308,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R435 T741 T765 themeOf RIP1 Kinase,RIP1 Kinase Activation during Necroptosis
R429 T729 T757 themeOf Akt,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R430 T729 T758 themeOf Akt,"During necroptosis, Akt is activated in a RIP1 dependent fashion through its phosphorylation on Thr308"
R431 T734 T764 themeOf TNFα,TNFα production
R432 T737 T729 partOf on Thr308,Akt

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T487 0-3 NNP denotes Akt
T488 4-13 VBZ denotes Regulates
T489 14-18 NNP denotes TNFα
T490 19-28 NNP denotes Synthesis
T491 29-39 NNP denotes Downstream
T492 40-42 IN denotes of
T493 43-47 NNP denotes RIP1
T494 48-54 NNP denotes Kinase
T495 55-65 NNP denotes Activation
T496 66-72 IN denotes during
T497 73-84 NNP denotes Necroptosis
T626 932-933 , denotes ,
T625 924-932 NN denotes activity
T624 920-923 JJ denotes Akt
T623 918-919 . denotes .
T622 917-918 -RRB- denotes )
T621 911-917 NN denotes mTORC1
T620 910-911 -LRB- denotes (
T619 908-909 CD denotes 1
T618 900-907 JJ denotes complex
T617 890-899 NNP denotes Rapamycin
T616 887-889 IN denotes of
T615 880-886 NNP denotes Target
T614 870-879 JJ denotes mammalian
T613 867-869 IN denotes of
T612 857-866 VBG denotes targeting
T611 846-856 JJ denotes downstream
T610 838-845 IN denotes through
T609 826-837 NN denotes necroptosis
T608 817-825 VBZ denotes controls
T607 813-816 NNP denotes Akt
T606 811-812 . denotes .
T605 807-811 NNP denotes RIP1
T604 803-806 CC denotes and
T603 795-802 NNS denotes factors
T602 788-794 NN denotes growth
T601 783-787 DT denotes both
T600 778-782 IN denotes from
T599 771-777 NNS denotes inputs
T598 761-770 VBG denotes signaling
T597 749-760 JJ denotes independent
T596 740-748 VBZ denotes requires
T595 729-739 NN denotes activation
T594 724-728 DT denotes this
T533 363-365 PRP denotes we
T532 361-362 , denotes ,
T531 357-361 NN denotes work
T530 352-356 DT denotes this
T529 349-351 IN denotes In
T528 347-348 . denotes .
T527 346-347 -RRB- denotes )
T526 342-346 NNP denotes SIRS
T525 341-342 -LRB- denotes (
T524 332-340 NN denotes syndrome
T523 323-331 NN denotes response
T522 310-322 JJ denotes inflammatory
T521 301-309 JJ denotes systemic
T520 297-300 CC denotes and
T519 284-296 NN denotes inflammation
T518 273-283 JJ denotes intestinal
T517 263-272 VBG denotes including
T516 254-262 NNS denotes diseases
T515 246-253 JJ denotes various
T514 243-245 IN denotes of
T513 230-242 NN denotes pathogenesis
T512 226-229 DT denotes the
T511 223-225 IN denotes in
T510 212-222 VBN denotes implicated
T509 207-211 VBN denotes been
T508 203-206 VBZ denotes has
T507 198-202 WDT denotes that
T506 192-197 NN denotes death
T505 187-191 NN denotes cell
T504 178-186 JJ denotes necrotic
T503 175-177 IN denotes of
T502 170-174 NN denotes form
T501 160-169 JJ denotes regulated
T500 158-159 DT denotes a
T499 155-157 VBZ denotes is
T498 143-154 NNP denotes Necroptosis
T573 605-611 IN denotes During
T572 603-604 . denotes .
T571 593-603 NN denotes production
T570 588-592 JJ denotes TNFα
T569 585-587 IN denotes in
T568 580-584 NN denotes role
T567 576-579 JJ denotes key
T566 574-575 DT denotes a
T565 568-573 VBZ denotes plays
T564 564-567 CC denotes and
T563 558-563 NNS denotes cells
T562 553-557 CD denotes L929
T561 550-552 IN denotes in
T560 538-549 NN denotes necroptosis
T559 534-537 IN denotes for
T558 525-533 JJ denotes critical
T557 522-524 VBZ denotes is
T556 513-521 NN denotes activity
T555 506-512 NN denotes kinase
T554 502-505 NNP denotes Akt
T553 497-501 IN denotes that
T552 492-496 VBP denotes show
T551 489-491 PRP denotes We
T550 487-488 . denotes .
T549 481-487 NN denotes kinase
T548 479-480 -RRB- denotes )
T547 475-479 CD denotes RIP1
T546 474-475 -LRB- denotes (
T545 464-473 NN denotes protein-1
T544 452-463 VBG denotes interacting
T543 443-451 NN denotes receptor
T542 434-442 NN denotes mediator
T541 422-433 NN denotes necroptosis
T540 418-421 DT denotes the
T539 415-417 IN denotes by
T538 404-414 VBN denotes controlled
T537 393-403 NNS denotes mechanisms
T536 383-392 VBG denotes signaling
T535 379-382 DT denotes the
T534 366-378 VBD denotes investigated
T593 722-723 , denotes ,
T592 717-722 NNS denotes cells
T591 712-716 CD denotes L929
T590 709-711 IN denotes In
T589 707-708 . denotes .
T588 701-707 NNP denotes Thr308
T587 698-700 IN denotes on
T586 682-697 NN denotes phosphorylation
T585 678-681 PRP$ denotes its
T584 670-677 IN denotes through
T583 662-669 NN denotes fashion
T582 652-661 JJ denotes dependent
T581 647-651 NNP denotes RIP1
T580 645-646 DT denotes a
T579 642-644 IN denotes in
T578 632-641 VBN denotes activated
T577 629-631 VBZ denotes is
T576 625-628 NNP denotes Akt
T575 623-624 , denotes ,
T574 612-623 NN denotes necroptosis
R228 T488 T488 ROOT Regulates,Regulates
R229 T489 T491 compound TNFα,Downstream
R230 T490 T491 compound Synthesis,Downstream
R231 T491 T488 dobj Downstream,Regulates
R232 T492 T491 prep of,Downstream
R233 T493 T494 compound RIP1,Kinase
R234 T494 T495 compound Kinase,Activation
R235 T495 T492 pobj Activation,of
R236 T496 T488 prep during,Regulates
R237 T497 T498 compound Necroptosis,Necroptosis
R238 T498 T496 pobj Necroptosis,during
R239 T499 T488 conj is,Regulates
R240 T500 T502 det a,form
R241 T501 T502 amod regulated,form
R242 T502 T499 attr form,is
R243 T503 T502 prep of,form
R244 T504 T506 amod necrotic,death
R245 T505 T506 compound cell,death
R246 T506 T503 pobj death,of
R247 T507 T510 nsubjpass that,implicated
R248 T508 T510 aux has,implicated
R249 T509 T510 auxpass been,implicated
R250 T510 T506 relcl implicated,death
R251 T511 T510 prep in,implicated
R252 T512 T513 det the,pathogenesis
R253 T513 T511 pobj pathogenesis,in
R254 T514 T513 prep of,pathogenesis
R255 T515 T516 amod various,diseases
R256 T516 T514 pobj diseases,of
R257 T517 T516 prep including,diseases
R258 T518 T519 amod intestinal,inflammation
R259 T519 T517 pobj inflammation,including
R260 T520 T519 cc and,inflammation
R261 T521 T524 amod systemic,syndrome
R262 T522 T523 amod inflammatory,response
R263 T523 T524 compound response,syndrome
R264 T524 T519 conj syndrome,inflammation
R265 T525 T524 punct (,syndrome
R266 T526 T524 appos SIRS,syndrome
R267 T527 T524 punct ),syndrome
R268 T528 T488 punct .,Regulates
R269 T529 T534 prep In,investigated
R270 T530 T531 det this,work
R271 T531 T529 pobj work,In
R272 T532 T534 punct ",",investigated
R273 T533 T534 nsubj we,investigated
R274 T534 T534 ROOT investigated,investigated
R275 T535 T537 det the,mechanisms
R276 T536 T537 amod signaling,mechanisms
R277 T537 T534 dobj mechanisms,investigated
R278 T538 T537 acl controlled,mechanisms
R279 T539 T538 agent by,controlled
R280 T540 T543 det the,receptor
R281 T541 T542 amod necroptosis,mediator
R282 T542 T543 compound mediator,receptor
R283 T543 T539 pobj receptor,by
R284 T544 T543 acl interacting,receptor
R285 T545 T544 dobj protein-1,interacting
R286 T546 T545 punct (,protein-1
R287 T547 T545 appos RIP1,protein-1
R288 T548 T545 punct ),protein-1
R289 T549 T543 conj kinase,receptor
R290 T550 T534 punct .,investigated
R291 T551 T552 nsubj We,show
R292 T552 T552 ROOT show,show
R293 T553 T557 mark that,is
R294 T554 T556 compound Akt,activity
R295 T555 T556 compound kinase,activity
R296 T556 T557 nsubj activity,is
R297 T557 T552 ccomp is,show
R298 T558 T557 acomp critical,is
R299 T559 T558 prep for,critical
R300 T560 T559 pobj necroptosis,for
R301 T561 T557 prep in,is
R302 T562 T563 nummod L929,cells
R303 T563 T561 pobj cells,in
R304 T564 T557 cc and,is
R305 T565 T557 conj plays,is
R306 T566 T568 det a,role
R307 T567 T568 amod key,role
R308 T568 T565 dobj role,plays
R309 T569 T568 prep in,role
R310 T570 T571 amod TNFα,production
R311 T571 T569 pobj production,in
R312 T572 T552 punct .,show
R313 T573 T578 prep During,activated
R314 T574 T573 pobj necroptosis,During
R315 T575 T578 punct ",",activated
R316 T576 T578 nsubjpass Akt,activated
R317 T577 T578 auxpass is,activated
R318 T578 T578 ROOT activated,activated
R319 T579 T578 prep in,activated
R320 T580 T583 det a,fashion
R321 T581 T583 nmod RIP1,fashion
R322 T582 T583 amod dependent,fashion
R323 T583 T579 pobj fashion,in
R324 T584 T578 prep through,activated
R325 T585 T586 poss its,phosphorylation
R326 T586 T584 pobj phosphorylation,through
R327 T587 T586 prep on,phosphorylation
R328 T588 T587 pobj Thr308,on
R329 T589 T578 punct .,activated
R330 T590 T596 prep In,requires
R331 T591 T592 nummod L929,cells
R332 T592 T590 pobj cells,In
R333 T593 T596 punct ",",requires
R334 T594 T595 det this,activation
R335 T595 T596 nsubj activation,requires
R336 T596 T596 ROOT requires,requires
R337 T597 T599 amod independent,inputs
R338 T598 T599 amod signaling,inputs
R339 T599 T596 dobj inputs,requires
R340 T600 T599 prep from,inputs
R341 T601 T603 det both,factors
R342 T602 T603 compound growth,factors
R343 T603 T600 pobj factors,from
R344 T604 T603 cc and,factors
R345 T605 T603 conj RIP1,factors
R346 T606 T596 punct .,requires
R347 T607 T608 nsubj Akt,controls
R348 T608 T608 ROOT controls,controls
R349 T609 T608 dobj necroptosis,controls
R350 T610 T608 prep through,controls
R351 T611 T612 amod downstream,targeting
R352 T612 T610 pobj targeting,through
R353 T613 T612 prep of,targeting
R354 T614 T615 amod mammalian,Target
R355 T615 T613 pobj Target,of
R356 T616 T615 prep of,Target
R357 T617 T616 pobj Rapamycin,of
R358 T618 T621 nmod complex,mTORC1
R359 T619 T618 nummod 1,complex
R360 T620 T621 punct (,mTORC1
R361 T621 T612 conj mTORC1,targeting
R362 T622 T621 punct ),mTORC1
R363 T623 T608 punct .,controls
R364 T624 T625 amod Akt,activity
R365 T625 T625 ROOT activity,activity
R366 T626 T625 punct ",",activity
R227 T487 T488 nsubj Akt,Regulates

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T456 0-3 Protein denotes Akt
T457 14-18 Protein denotes TNFα
T458 43-54 Protein denotes RIP1 Kinase
T459 19-28 Gene_expression denotes Synthesis
T460 55-65 Positive_regulation denotes Activation
T461 4-13 Regulation denotes Regulates
T476 920-923 Protein denotes Akt
T475 807-811 Protein denotes RIP1
T474 632-641 Positive_regulation denotes activated
T473 682-697 Phosphorylation denotes phosphorylation
T472 632-641 Positive_regulation denotes activated
T471 701-707 Protein denotes Thr308
T470 647-651 Protein denotes RIP1
T469 625-628 Protein denotes Akt
T468 593-603 Gene_expression denotes production
T467 588-592 Protein denotes TNFα
T466 502-512 Protein denotes Akt kinase
T465 404-414 Regulation denotes controlled
T464 404-414 Regulation denotes controlled
T463 475-479 Protein denotes RIP1
T462 434-473 Protein denotes mediator receptor interacting protein-1
R212 T456 T461 causeOf Akt,Regulates
R213 T457 T459 themeOf TNFα,Synthesis
R214 T458 T460 themeOf RIP1 Kinase,Activation
R215 T459 T461 themeOf Synthesis,Regulates
R216 T462 T464 themeOf mediator receptor interacting protein-1,controlled
R217 T463 T465 themeOf RIP1,controlled
R218 T467 T468 themeOf TNFα,production
R219 T469 T472 themeOf Akt,activated
R220 T471 T473 themeOf Thr308,phosphorylation
R221 T473 T474 themeOf phosphorylation,activated

test3

Id Subject Object Predicate Lexical cue
T29 14-18 Protein denotes TNFα
T30 43-47 Protein denotes RIP1
T39 4-13 Regulation denotes Regulates
T40 14-18 Protein denotes TNFα
T41 19-28 Gene_expression denotes Synthesis
T42 43-47 Protein denotes RIP1
T52 807-811 Protein denotes RIP1
T51 682-697 Phosphorylation denotes phosphorylation
T50 647-651 Protein denotes RIP1
T49 632-641 Positive_regulation denotes activated
T48 593-603 Gene_expression denotes production
T47 588-592 Protein denotes TNFα
T46 580-584 Regulation denotes role
T45 475-479 Protein denotes RIP1
T44 443-473 Protein denotes receptor interacting protein-1
T43 404-414 Regulation denotes controlled
T35 807-811 Protein denotes RIP1
T34 647-651 Protein denotes RIP1
T33 588-592 Protein denotes TNFα
T32 475-479 Protein denotes RIP1
T31 443-473 Protein denotes receptor interacting protein-1
R6 T40 T41 themeOf TNFα,Synthesis
R7 T41 T39 themeOf Synthesis,Regulates
R8 T44 T43 causeOf receptor interacting protein-1,controlled
R9 T45 T44 equivalentTo RIP1,receptor interacting protein-1
R10 T47 T48 themeOf TNFα,production
R11 T48 T46 themeOf production,role
R12 T50 T49 themeOf RIP1,activated