PMC:3567831 / 21028-22511 JSONTXT

{"project":"0_colil","denotations":[{"id":"22761504-15573275-6884","span":{"begin":213,"end":215},"obj":"15573275"},{"id":"22761504-18442532-6885","span":{"begin":730,"end":732},"obj":"18442532"},{"id":"22761504-15152297-6886","span":{"begin":953,"end":955},"obj":"15152297"}],"text":"As mitral valve leaflets and subvalvular apparatus abnormalities play an important role in the pathologies of obstructive HCM, surgical management of the mitral valve has been considered a vital part of myectomy [22]. According to the analysis of preoperative echocardiography in this study, SAM was accessed in all and MR in 73 patients (78.5%), of whom 41 were more than moderate level. For many patients, SAM and MR could disappear or diminish automatically after myectomy. However, some patients had mitral valve abnormities, which also need special surgical treatment during the operations, or it would negatively influence the surgical outcome. For them, mitral valve repair or plasty is recommended as the priority choice [23]. According to our practice, MVR can be avoided in most patients with degenerative MR and HCM, and it is indicated only if the mitral valve cannot be repaired because of severe pathological changes such as endocarditis [24] or of other procedures have failed to relieve the LVOT gradient. In this group, SAM disappeared postoperatively including those who had MVP, except only one still had mild SAM but without mitral-septal contact. In this group, MVR was carried out in 10 cases (10 of 93). Six of them had severely damaged mitral valve, which could not be repaired. While for the other four cases, intraoperative TEE showed that the LVOT gradient and SAM had not been resolved perfectly after initial myectomy and MVP, so they had MVR thereafter."}

{"project":"TEST0","denotations":[{"id":"22761504-213-219-6884","span":{"begin":213,"end":215},"obj":"[\"15573275\"]"},{"id":"22761504-79-85-6885","span":{"begin":730,"end":732},"obj":"[\"18442532\"]"},{"id":"22761504-218-224-6886","span":{"begin":953,"end":955},"obj":"[\"15152297\"]"}],"text":"As mitral valve leaflets and subvalvular apparatus abnormalities play an important role in the pathologies of obstructive HCM, surgical management of the mitral valve has been considered a vital part of myectomy [22]. According to the analysis of preoperative echocardiography in this study, SAM was accessed in all and MR in 73 patients (78.5%), of whom 41 were more than moderate level. For many patients, SAM and MR could disappear or diminish automatically after myectomy. However, some patients had mitral valve abnormities, which also need special surgical treatment during the operations, or it would negatively influence the surgical outcome. For them, mitral valve repair or plasty is recommended as the priority choice [23]. According to our practice, MVR can be avoided in most patients with degenerative MR and HCM, and it is indicated only if the mitral valve cannot be repaired because of severe pathological changes such as endocarditis [24] or of other procedures have failed to relieve the LVOT gradient. In this group, SAM disappeared postoperatively including those who had MVP, except only one still had mild SAM but without mitral-septal contact. In this group, MVR was carried out in 10 cases (10 of 93). Six of them had severely damaged mitral valve, which could not be repaired. While for the other four cases, intraoperative TEE showed that the LVOT gradient and SAM had not been resolved perfectly after initial myectomy and MVP, so they had MVR thereafter."}

{"project":"2_test","denotations":[{"id":"22761504-15573275-28905050","span":{"begin":213,"end":215},"obj":"15573275"},{"id":"22761504-18442532-28905051","span":{"begin":730,"end":732},"obj":"18442532"},{"id":"22761504-15152297-28905052","span":{"begin":953,"end":955},"obj":"15152297"}],"text":"As mitral valve leaflets and subvalvular apparatus abnormalities play an important role in the pathologies of obstructive HCM, surgical management of the mitral valve has been considered a vital part of myectomy [22]. According to the analysis of preoperative echocardiography in this study, SAM was accessed in all and MR in 73 patients (78.5%), of whom 41 were more than moderate level. For many patients, SAM and MR could disappear or diminish automatically after myectomy. However, some patients had mitral valve abnormities, which also need special surgical treatment during the operations, or it would negatively influence the surgical outcome. For them, mitral valve repair or plasty is recommended as the priority choice [23]. According to our practice, MVR can be avoided in most patients with degenerative MR and HCM, and it is indicated only if the mitral valve cannot be repaired because of severe pathological changes such as endocarditis [24] or of other procedures have failed to relieve the LVOT gradient. In this group, SAM disappeared postoperatively including those who had MVP, except only one still had mild SAM but without mitral-septal contact. In this group, MVR was carried out in 10 cases (10 of 93). Six of them had severely damaged mitral valve, which could not be repaired. While for the other four cases, intraoperative TEE showed that the LVOT gradient and SAM had not been resolved perfectly after initial myectomy and MVP, so they had MVR thereafter."}

{"project":"MyTest","denotations":[{"id":"22761504-15573275-28905050","span":{"begin":213,"end":215},"obj":"15573275"},{"id":"22761504-18442532-28905051","span":{"begin":730,"end":732},"obj":"18442532"},{"id":"22761504-15152297-28905052","span":{"begin":953,"end":955},"obj":"15152297"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"As mitral valve leaflets and subvalvular apparatus abnormalities play an important role in the pathologies of obstructive HCM, surgical management of the mitral valve has been considered a vital part of myectomy [22]. According to the analysis of preoperative echocardiography in this study, SAM was accessed in all and MR in 73 patients (78.5%), of whom 41 were more than moderate level. For many patients, SAM and MR could disappear or diminish automatically after myectomy. However, some patients had mitral valve abnormities, which also need special surgical treatment during the operations, or it would negatively influence the surgical outcome. For them, mitral valve repair or plasty is recommended as the priority choice [23]. According to our practice, MVR can be avoided in most patients with degenerative MR and HCM, and it is indicated only if the mitral valve cannot be repaired because of severe pathological changes such as endocarditis [24] or of other procedures have failed to relieve the LVOT gradient. In this group, SAM disappeared postoperatively including those who had MVP, except only one still had mild SAM but without mitral-septal contact. In this group, MVR was carried out in 10 cases (10 of 93). Six of them had severely damaged mitral valve, which could not be repaired. While for the other four cases, intraoperative TEE showed that the LVOT gradient and SAM had not been resolved perfectly after initial myectomy and MVP, so they had MVR thereafter."}

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