PMC:3500718 / 627-1677 JSONTXT

{"project":"2_test","denotations":[{"id":"23039908-20073618-145186972","span":{"begin":241,"end":242},"obj":"20073618"},{"id":"23039908-22096700-145186973","span":{"begin":369,"end":370},"obj":"22096700"},{"id":"23039908-15761716-145186974","span":{"begin":660,"end":661},"obj":"15761716"},{"id":"23039908-16439005-145186975","span":{"begin":817,"end":818},"obj":"16439005"}],"text":"Gastrointestinal stromal tumors (GISTs) are nonepithelial, mesenchymal tumors that arise from the intestinal cells of Cajal (ICC) or their stem cell precursors, and constitute approximately 2% of all neoplasms of the gastrointestinal tract [1]. These tumors very rarely occur in children and young adults, who account for approximately 1.4% of all patients with GISTs [2]. The tumors arise in the stomach in 40% to 70% of cases and in the small intestine in 20% to 40% of cases, while less than 10% of tumors occur in the esophagus, colon, or rectum; they usually present in adults over 40 years of age, with a peak incidence in the sixth and seventh decades [3]. They may also originate from extragastrointestinal tract sites, such as the omentum, mesentery, retroperitoneum, pancreas, fallopian tubes, or uterus [4,5]. These are termed extragastrointestinal stromal tumors (eGISTs), and usually behave more aggressively. In this report, we present the case of a GIST of the mesoappendix, and focus on the CT findings and a review of the literature."}