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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3480681","sourcedb":"PMC","sourceid":"3480681","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3480681","text":"Fig. 2 Roles of alternative splicing in cancer. Dysfunctional proteins are generated by alternative splicing in cancer-related genes (oncogenic and tumor suppressor genes), increasing genomic instability. These aberrant proteins help cancerous cells to promote their growth, proliferation, and metastasis continuously (tumorigenesis). Variants of cancer-related genes expressed specifically or differently with their crucial roles for tumorigenesis could be potential biomarkers to distinguish between normal and cancer cells.","tracks":[]}