PMC:340383 / 333-961 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T275","span":{"begin":0,"end":3},"obj":"DT"},{"id":"T276","span":{"begin":20,"end":26},"obj":"NN"},{"id":"T277","span":{"begin":4,"end":9},"obj":"JJ"},{"id":"T278","span":{"begin":10,"end":14},"obj":"NN"},{"id":"T279","span":{"begin":15,"end":19},"obj":"NN"},{"id":"T280","span":{"begin":26,"end":27},"obj":"."},{"id":"T281","span":{"begin":27,"end":36},"obj":"sentence"},{"id":"T282","span":{"begin":29,"end":36},"obj":"NNS"},{"id":"T283","span":{"begin":36,"end":237},"obj":"sentence"},{"id":"T284","span":{"begin":37,"end":40},"obj":"DT"},{"id":"T285","span":{"begin":51,"end":56},"obj":"NNS"},{"id":"T286","span":{"begin":41,"end":45},"obj":"CD"},{"id":"T287","span":{"begin":46,"end":50},"obj":"NN"},{"id":"T288","span":{"begin":89,"end":96},"obj":"VBP"},{"id":"T289","span":{"begin":57,"end":58},"obj":"-LRB-"},{"id":"T290","span":{"begin":58,"end":63},"obj":"NN"},{"id":"T291","span":{"begin":63,"end":65},"obj":","},{"id":"T292","span":{"begin":65,"end":70},"obj":"NN"},{"id":"T293","span":{"begin":70,"end":72},"obj":","},{"id":"T294","span":{"begin":72,"end":77},"obj":"NN"},{"id":"T295","span":{"begin":78,"end":81},"obj":"CC"},{"id":"T296","span":{"begin":82,"end":87},"obj":"NN"},{"id":"T297","span":{"begin":87,"end":88},"obj":"-RRB-"},{"id":"T298","span":{"begin":97,"end":102},"obj":"CD"},{"id":"T299","span":{"begin":103,"end":105},"obj":"NNS"},{"id":"T300","span":{"begin":105,"end":107},"obj":","},{"id":"T301","span":{"begin":107,"end":112},"obj":"CD"},{"id":"T302","span":{"begin":113,"end":115},"obj":"NNS"},{"id":"T303","span":{"begin":115,"end":117},"obj":","},{"id":"T304","span":{"begin":117,"end":122},"obj":"CD"},{"id":"T305","span":{"begin":123,"end":125},"obj":"NNS"},{"id":"T306","span":{"begin":126,"end":129},"obj":"CC"},{"id":"T307","span":{"begin":130,"end":135},"obj":"CD"},{"id":"T308","span":{"begin":136,"end":138},"obj":"NNS"},{"id":"T309","span":{"begin":139,"end":141},"obj":"IN"},{"id":"T310","span":{"begin":142,"end":146},"obj":"NN"},{"id":"T311","span":{"begin":147,"end":156},"obj":"NNS"},{"id":"T312","span":{"begin":156,"end":158},"obj":","},{"id":"T313","span":{"begin":158,"end":161},"obj":"CC"},{"id":"T314","span":{"begin":162,"end":168},"obj":"VBP"},{"id":"T315","span":{"begin":169,"end":176},"obj":"VBN"},{"id":"T316","span":{"begin":177,"end":185},"obj":"NN"},{"id":"T317","span":{"begin":186,"end":188},"obj":"IN"},{"id":"T318","span":{"begin":189,"end":192},"obj":"CD"},{"id":"T319","span":{"begin":217,"end":222},"obj":"NNS"},{"id":"T320","span":{"begin":192,"end":194},"obj":","},{"id":"T321","span":{"begin":194,"end":197},"obj":"CD"},{"id":"T322","span":{"begin":197,"end":199},"obj":","},{"id":"T323","span":{"begin":199,"end":202},"obj":"CD"},{"id":"T324","span":{"begin":203,"end":206},"obj":"CC"},{"id":"T325","span":{"begin":207,"end":210},"obj":"CD"},{"id":"T326","span":{"begin":211,"end":216},"obj":"NN"},{"id":"T327","span":{"begin":222,"end":224},"obj":","},{"id":"T328","span":{"begin":224,"end":236},"obj":"RB"},{"id":"T329","span":{"begin":236,"end":237},"obj":"."},{"id":"T330","span":{"begin":237,"end":368},"obj":"sentence"},{"id":"T331","span":{"begin":238,"end":241},"obj":"DT"},{"id":"T332","span":{"begin":253,"end":258},"obj":"NNS"},{"id":"T333","span":{"begin":242,"end":247},"obj":"NN"},{"id":"T334","span":{"begin":248,"end":252},"obj":"NN"},{"id":"T335","span":{"begin":259,"end":265},"obj":"VBD"},{"id":"T336","span":{"begin":266,"end":270},"obj":"RB"},{"id":"T337","span":{"begin":271,"end":277},"obj":"JJ"},{"id":"T338","span":{"begin":278,"end":288},"obj":"NNS"},{"id":"T339","span":{"begin":289,"end":290},"obj":"-LRB-"},{"id":"T340","span":{"begin":293,"end":294},"obj":"NN"},{"id":"T341","span":{"begin":290,"end":291},"obj":"SYM"},{"id":"T342","span":{"begin":291,"end":293},"obj":"CD"},{"id":"T343","span":{"begin":294,"end":295},"obj":"-RRB-"},{"id":"T344","span":{"begin":296,"end":298},"obj":"IN"},{"id":"T345","span":{"begin":299,"end":303},"obj":"CC"},{"id":"T346","span":{"begin":304,"end":314},"obj":"NN"},{"id":"T347","span":{"begin":330,"end":339},"obj":"NNS"},{"id":"T348","span":{"begin":315,"end":318},"obj":"CC"},{"id":"T349","span":{"begin":319,"end":324},"obj":"NN"},{"id":"T350","span":{"begin":325,"end":329},"obj":"NN"},{"id":"T351","span":{"begin":340,"end":342},"obj":"IN"},{"id":"T352","span":{"begin":343,"end":348},"obj":"PRP$"},{"id":"T353","span":{"begin":355,"end":367},"obj":"NNS"},{"id":"T354","span":{"begin":349,"end":354},"obj":"JJ"},{"id":"T355","span":{"begin":367,"end":368},"obj":"."},{"id":"T356","span":{"begin":368,"end":522},"obj":"sentence"},{"id":"T357","span":{"begin":369,"end":371},"obj":"IN"},{"id":"T358","span":{"begin":476,"end":485},"obj":"VBN"},{"id":"T359","span":{"begin":372,"end":380},"obj":"NN"},{"id":"T360","span":{"begin":380,"end":382},"obj":","},{"id":"T361","span":{"begin":382,"end":386},"obj":"CC"},{"id":"T362","span":{"begin":387,"end":397},"obj":"NN"},{"id":"T363","span":{"begin":413,"end":422},"obj":"NNS"},{"id":"T364","span":{"begin":398,"end":401},"obj":"CC"},{"id":"T365","span":{"begin":402,"end":407},"obj":"NN"},{"id":"T366","span":{"begin":408,"end":412},"obj":"NN"},{"id":"T367","span":{"begin":423,"end":429},"obj":"IN"},{"id":"T368","span":{"begin":430,"end":433},"obj":"DT"},{"id":"T369","span":{"begin":452,"end":458},"obj":"NN"},{"id":"T370","span":{"begin":434,"end":441},"obj":"JJ"},{"id":"T371","span":{"begin":442,"end":451},"obj":"VBN"},{"id":"T372","span":{"begin":459,"end":460},"obj":"-LRB-"},{"id":"T373","span":{"begin":460,"end":463},"obj":"NN"},{"id":"T374","span":{"begin":463,"end":464},"obj":"-RRB-"},{"id":"T375","span":{"begin":465,"end":468},"obj":"VBP"},{"id":"T376","span":{"begin":469,"end":475},"obj":"RB"},{"id":"T377","span":{"begin":486,"end":488},"obj":"IN"},{"id":"T378","span":{"begin":489,"end":493},"obj":"JJ"},{"id":"T379","span":{"begin":514,"end":521},"obj":"NNS"},{"id":"T380","span":{"begin":494,"end":503},"obj":"JJ"},{"id":"T381","span":{"begin":504,"end":513},"obj":"JJ"},{"id":"T382","span":{"begin":521,"end":522},"obj":"."},{"id":"T384","span":{"begin":523,"end":535},"obj":"RB"},{"id":"T385","span":{"begin":551,"end":557},"obj":"VBD"},{"id":"T386","span":{"begin":535,"end":537},"obj":","},{"id":"T387","span":{"begin":537,"end":541},"obj":"NN"},{"id":"T388","span":{"begin":542,"end":550},"obj":"NN"},{"id":"T389","span":{"begin":558,"end":562},"obj":"RB"},{"id":"T390","span":{"begin":563,"end":569},"obj":"JJ"},{"id":"T391","span":{"begin":573,"end":583},"obj":"NNS"},{"id":"T392","span":{"begin":570,"end":572},"obj":"NN"},{"id":"T393","span":{"begin":584,"end":586},"obj":"IN"},{"id":"T394","span":{"begin":587,"end":590},"obj":"DT"},{"id":"T395","span":{"begin":605,"end":612},"obj":"NN"},{"id":"T396","span":{"begin":591,"end":599},"obj":"NNS"},{"id":"T397","span":{"begin":600,"end":604},"obj":"NN"},{"id":"T398","span":{"begin":613,"end":614},"obj":"-LRB-"},{"id":"T400","span":{"begin":614,"end":616},"obj":"CD"},{"id":"T401","span":{"begin":616,"end":617},"obj":"NN"},{"id":"T402","span":{"begin":618,"end":620},"obj":"NN"}],"relations":[{"id":"R52","pred":"det","subj":"T275","obj":"T276"},{"id":"R54","pred":"amod","subj":"T277","obj":"T276"},{"id":"R55","pred":"compound","subj":"T278","obj":"T276"},{"id":"R56","pred":"compound","subj":"T279","obj":"T276"},{"id":"R58","pred":"det","subj":"T284","obj":"T285"},{"id":"R59","pred":"nsubj","subj":"T285","obj":"T288"},{"id":"R60","pred":"nummod","subj":"T286","obj":"T285"},{"id":"R61","pred":"compound","subj":"T287","obj":"T285"},{"id":"R62","pred":"punct","subj":"T289","obj":"T285"},{"id":"R63","pred":"appos","subj":"T290","obj":"T285"},{"id":"R64","pred":"punct","subj":"T291","obj":"T290"},{"id":"R65","pred":"conj","subj":"T292","obj":"T290"},{"id":"R66","pred":"punct","subj":"T293","obj":"T292"},{"id":"R67","pred":"conj","subj":"T294","obj":"T292"},{"id":"R68","pred":"cc","subj":"T295","obj":"T294"},{"id":"R69","pred":"conj","subj":"T296","obj":"T294"},{"id":"R70","pred":"punct","subj":"T297","obj":"T288"},{"id":"R71","pred":"nummod","subj":"T298","obj":"T299"},{"id":"R72","pred":"dobj","subj":"T299","obj":"T288"},{"id":"R73","pred":"punct","subj":"T300","obj":"T299"},{"id":"R74","pred":"nummod","subj":"T301","obj":"T302"},{"id":"R75","pred":"conj","subj":"T302","obj":"T299"},{"id":"R76","pred":"punct","subj":"T303","obj":"T302"},{"id":"R77","pred":"nummod","subj":"T304","obj":"T305"},{"id":"R78","pred":"conj","subj":"T305","obj":"T302"},{"id":"R79","pred":"cc","subj":"T306","obj":"T305"},{"id":"R80","pred":"nummod","subj":"T307","obj":"T308"},{"id":"R81","pred":"conj","subj":"T308","obj":"T305"},{"id":"R82","pred":"prep","subj":"T309","obj":"T299"},{"id":"R83","pred":"compound","subj":"T310","obj":"T311"},{"id":"R84","pred":"pobj","subj":"T311","obj":"T309"},{"id":"R85","pred":"punct","subj":"T312","obj":"T288"},{"id":"R86","pred":"cc","subj":"T313","obj":"T288"},{"id":"R87","pred":"conj","subj":"T314","obj":"T288"},{"id":"R88","pred":"amod","subj":"T315","obj":"T316"},{"id":"R89","pred":"dobj","subj":"T316","obj":"T314"},{"id":"R90","pred":"prep","subj":"T317","obj":"T316"},{"id":"R91","pred":"nummod","subj":"T318","obj":"T319"},{"id":"R92","pred":"pobj","subj":"T319","obj":"T317"},{"id":"R93","pred":"punct","subj":"T320","obj":"T318"},{"id":"R94","pred":"conj","subj":"T321","obj":"T318"},{"id":"R95","pred":"punct","subj":"T322","obj":"T321"},{"id":"R96","pred":"conj","subj":"T323","obj":"T321"},{"id":"R97","pred":"cc","subj":"T324","obj":"T323"},{"id":"R98","pred":"conj","subj":"T325","obj":"T323"},{"id":"R99","pred":"compound","subj":"T326","obj":"T319"},{"id":"R100","pred":"punct","subj":"T327","obj":"T314"},{"id":"R101","pred":"advmod","subj":"T328","obj":"T314"},{"id":"R102","pred":"punct","subj":"T329","obj":"T288"},{"id":"R103","pred":"det","subj":"T331","obj":"T332"},{"id":"R104","pred":"nsubj","subj":"T332","obj":"T335"},{"id":"R105","pred":"compound","subj":"T333","obj":"T332"},{"id":"R106","pred":"compound","subj":"T334","obj":"T332"},{"id":"R107","pred":"advmod","subj":"T336","obj":"T337"},{"id":"R108","pred":"amod","subj":"T337","obj":"T338"},{"id":"R109","pred":"dobj","subj":"T338","obj":"T335"},{"id":"R110","pred":"punct","subj":"T339","obj":"T340"},{"id":"R111","pred":"parataxis","subj":"T340","obj":"T338"},{"id":"R112","pred":"punct","subj":"T341","obj":"T342"},{"id":"R113","pred":"nummod","subj":"T342","obj":"T340"},{"id":"R114","pred":"punct","subj":"T343","obj":"T340"},{"id":"R115","pred":"prep","subj":"T344","obj":"T338"},{"id":"R116","pred":"preconj","subj":"T345","obj":"T346"},{"id":"R117","pred":"nmod","subj":"T346","obj":"T347"},{"id":"R118","pred":"pobj","subj":"T347","obj":"T344"},{"id":"R119","pred":"cc","subj":"T348","obj":"T346"},{"id":"R120","pred":"compound","subj":"T349","obj":"T350"},{"id":"R121","pred":"conj","subj":"T350","obj":"T346"},{"id":"R122","pred":"prep","subj":"T351","obj":"T338"},{"id":"R123","pred":"poss","subj":"T352","obj":"T353"},{"id":"R125","pred":"amod","subj":"T354","obj":"T353"},{"id":"R126","pred":"punct","subj":"T355","obj":"T335"},{"id":"R127","pred":"prep","subj":"T357","obj":"T358"},{"id":"R128","pred":"pobj","subj":"T359","obj":"T357"},{"id":"R129","pred":"punct","subj":"T360","obj":"T358"},{"id":"R130","pred":"preconj","subj":"T361","obj":"T362"},{"id":"R131","pred":"nmod","subj":"T362","obj":"T363"},{"id":"R132","pred":"nsubjpass","subj":"T363","obj":"T358"},{"id":"R133","pred":"cc","subj":"T364","obj":"T362"},{"id":"R134","pred":"compound","subj":"T365","obj":"T366"},{"id":"R135","pred":"conj","subj":"T366","obj":"T362"},{"id":"R136","pred":"prep","subj":"T367","obj":"T363"},{"id":"R137","pred":"det","subj":"T368","obj":"T369"},{"id":"R138","pred":"pobj","subj":"T369","obj":"T367"},{"id":"R139","pred":"amod","subj":"T370","obj":"T369"},{"id":"R140","pred":"amod","subj":"T371","obj":"T369"},{"id":"R141","pred":"punct","subj":"T372","obj":"T369"},{"id":"R142","pred":"appos","subj":"T373","obj":"T369"},{"id":"R143","pred":"punct","subj":"T374","obj":"T358"},{"id":"R144","pred":"auxpass","subj":"T375","obj":"T358"},{"id":"R145","pred":"advmod","subj":"T376","obj":"T358"},{"id":"R146","pred":"prep","subj":"T377","obj":"T358"},{"id":"R147","pred":"amod","subj":"T378","obj":"T379"},{"id":"R148","pred":"pobj","subj":"T379","obj":"T377"},{"id":"R149","pred":"amod","subj":"T380","obj":"T379"},{"id":"R150","pred":"amod","subj":"T381","obj":"T379"},{"id":"R151","pred":"punct","subj":"T382","obj":"T358"},{"id":"R152","pred":"advmod","subj":"T384","obj":"T385"},{"id":"R153","pred":"punct","subj":"T386","obj":"T385"},{"id":"R154","pred":"compound","subj":"T387","obj":"T388"},{"id":"R155","pred":"nsubj","subj":"T388","obj":"T385"},{"id":"R156","pred":"advmod","subj":"T389","obj":"T390"},{"id":"R157","pred":"amod","subj":"T390","obj":"T391"},{"id":"R159","pred":"compound","subj":"T392","obj":"T391"},{"id":"R160","pred":"prep","subj":"T393","obj":"T391"},{"id":"R161","pred":"det","subj":"T394","obj":"T395"},{"id":"R162","pred":"pobj","subj":"T395","obj":"T393"},{"id":"R163","pred":"compound","subj":"T396","obj":"T395"},{"id":"R164","pred":"compound","subj":"T397","obj":"T395"},{"id":"R167","pred":"nummod","subj":"T400","obj":"T401"},{"id":"R124","pred":"pobj","subj":"T353","obj":"T351"},{"id":"R158","pred":"dobj","subj":"T391","obj":"T385"}],"text":"the human ACDP gene family.\n\nResults\nThe four Acdp genes (Acdp1, Acdp2, Acdp3 and Acdp4) contain 3,631 bp, 3,244 bp, 2,684 bp and 2,743 bp of cDNA sequences, and encode deduced proteins of 951, 874, 713 and 771 amino acids, respectively. The mouse Acdp genes showed very strong homologies (\u003e90%) in both nucleotide and amino acid sequences to their human counterparts. In addition, both nucleotide and amino acid sequences within the Ancient Conserved Domain (ACD) are highly conserved in many different taxonomic species. Particularly, Acdp proteins showed very strong AA homologies to the bacteria CorC protein (35% AA identit"}

{"project":"craft-ca-core-dev","denotations":[{"id":"T67","span":{"begin":4,"end":9},"obj":"NCBITaxon:9606"},{"id":"T68","span":{"begin":15,"end":19},"obj":"SO:0000704"},{"id":"T69","span":{"begin":51,"end":56},"obj":"SO:0000704"},{"id":"T70","span":{"begin":58,"end":63},"obj":"PR:000005643"},{"id":"T71","span":{"begin":65,"end":70},"obj":"PR:000005644"},{"id":"T72","span":{"begin":72,"end":77},"obj":"PR:000005645"},{"id":"T73","span":{"begin":82,"end":87},"obj":"PR:000005646"},{"id":"T74","span":{"begin":103,"end":105},"obj":"SO:0000028"},{"id":"T75","span":{"begin":113,"end":115},"obj":"SO:0000028"},{"id":"T76","span":{"begin":123,"end":125},"obj":"SO:0000028"},{"id":"T77","span":{"begin":136,"end":138},"obj":"SO:0000028"},{"id":"T78","span":{"begin":242,"end":247},"obj":"NCBITaxon:10088"},{"id":"T79","span":{"begin":253,"end":258},"obj":"SO:0000704"},{"id":"T80","span":{"begin":278,"end":288},"obj":"SO:0000857"},{"id":"T81","span":{"begin":349,"end":354},"obj":"NCBITaxon:9606"},{"id":"T82","span":{"begin":452,"end":458},"obj":"SO:0000417"},{"id":"T83","span":{"begin":504,"end":521},"obj":"NCBITaxon:species"},{"id":"T84","span":{"begin":573,"end":583},"obj":"SO:0000857"},{"id":"T85","span":{"begin":591,"end":599},"obj":"NCBITaxon:2"},{"id":"T86","span":{"begin":600,"end":604},"obj":"PR:000022321"}],"text":"the human ACDP gene family.\n\nResults\nThe four Acdp genes (Acdp1, Acdp2, Acdp3 and Acdp4) contain 3,631 bp, 3,244 bp, 2,684 bp and 2,743 bp of cDNA sequences, and encode deduced proteins of 951, 874, 713 and 771 amino acids, respectively. The mouse Acdp genes showed very strong homologies (\u003e90%) in both nucleotide and amino acid sequences to their human counterparts. In addition, both nucleotide and amino acid sequences within the Ancient Conserved Domain (ACD) are highly conserved in many different taxonomic species. Particularly, Acdp proteins showed very strong AA homologies to the bacteria CorC protein (35% AA identit"}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T133","span":{"begin":4,"end":9},"obj":"NCBITaxon:9606"},{"id":"T134","span":{"begin":10,"end":14},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T135","span":{"begin":15,"end":19},"obj":"SO_EXT:0000704"},{"id":"T136","span":{"begin":46,"end":50},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T137","span":{"begin":51,"end":56},"obj":"SO_EXT:0000704"},{"id":"T138","span":{"begin":58,"end":63},"obj":"PR_EXT:000005643"},{"id":"T139","span":{"begin":65,"end":70},"obj":"PR_EXT:000005644"},{"id":"T140","span":{"begin":72,"end":77},"obj":"PR_EXT:000005645"},{"id":"T141","span":{"begin":82,"end":87},"obj":"PR_EXT:000005646"},{"id":"T142","span":{"begin":103,"end":105},"obj":"SO_EXT:0000028"},{"id":"T143","span":{"begin":113,"end":115},"obj":"SO_EXT:0000028"},{"id":"T144","span":{"begin":123,"end":125},"obj":"SO_EXT:0000028"},{"id":"T145","span":{"begin":136,"end":138},"obj":"SO_EXT:0000028"},{"id":"T146","span":{"begin":142,"end":146},"obj":"SO_EXT:cDNA"},{"id":"T147","span":{"begin":147,"end":156},"obj":"SO_EXT:biological_sequence"},{"id":"T148","span":{"begin":162,"end":168},"obj":"SO_EXT:sequence_coding_function"},{"id":"T149","span":{"begin":177,"end":185},"obj":"CHEBI_PR_EXT:protein"},{"id":"T150","span":{"begin":211,"end":222},"obj":"CHEBI_SO_EXT:amino_acid"},{"id":"T151","span":{"begin":242,"end":247},"obj":"NCBITaxon:10088"},{"id":"T152","span":{"begin":248,"end":252},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T153","span":{"begin":253,"end":258},"obj":"SO_EXT:0000704"},{"id":"T154","span":{"begin":278,"end":288},"obj":"SO:0000857"},{"id":"T155","span":{"begin":304,"end":314},"obj":"CHEBI_SO_EXT:nucleotide"},{"id":"T156","span":{"begin":319,"end":329},"obj":"CHEBI_SO_EXT:amino_acid"},{"id":"T157","span":{"begin":330,"end":339},"obj":"SO_EXT:biological_sequence"},{"id":"T158","span":{"begin":349,"end":354},"obj":"NCBITaxon:9606"},{"id":"T159","span":{"begin":387,"end":397},"obj":"CHEBI_SO_EXT:nucleotide"},{"id":"T160","span":{"begin":402,"end":412},"obj":"CHEBI_SO_EXT:amino_acid"},{"id":"T161","span":{"begin":413,"end":422},"obj":"SO_EXT:biological_sequence"},{"id":"T162","span":{"begin":442,"end":451},"obj":"SO_EXT:biological_conservation_process_or_quality"},{"id":"T163","span":{"begin":452,"end":458},"obj":"SO_EXT:0000417"},{"id":"T164","span":{"begin":476,"end":485},"obj":"SO_EXT:biological_conservation_process_or_quality"},{"id":"T165","span":{"begin":504,"end":521},"obj":"NCBITaxon:species"},{"id":"T166","span":{"begin":537,"end":541},"obj":"PR_EXT:ACDP_or_CNNM"},{"id":"T167","span":{"begin":542,"end":550},"obj":"CHEBI_PR_EXT:protein"},{"id":"T168","span":{"begin":570,"end":572},"obj":"CHEBI_SO_EXT:amino_acid"},{"id":"T169","span":{"begin":573,"end":583},"obj":"SO:0000857"},{"id":"T170","span":{"begin":591,"end":599},"obj":"NCBITaxon:2"},{"id":"T171","span":{"begin":600,"end":604},"obj":"PR_EXT:000022321"},{"id":"T172","span":{"begin":605,"end":612},"obj":"CHEBI_PR_EXT:protein"},{"id":"T173","span":{"begin":618,"end":620},"obj":"CHEBI_SO_EXT:amino_acid"}],"text":"the human ACDP gene family.\n\nResults\nThe four Acdp genes (Acdp1, Acdp2, Acdp3 and Acdp4) contain 3,631 bp, 3,244 bp, 2,684 bp and 2,743 bp of cDNA sequences, and encode deduced proteins of 951, 874, 713 and 771 amino acids, respectively. The mouse Acdp genes showed very strong homologies (\u003e90%) in both nucleotide and amino acid sequences to their human counterparts. In addition, both nucleotide and amino acid sequences within the Ancient Conserved Domain (ACD) are highly conserved in many different taxonomic species. Particularly, Acdp proteins showed very strong AA homologies to the bacteria CorC protein (35% AA identit"}