PMC:3396637 / 8840-10039 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3396637","sourcedb":"PMC","sourceid":"3396637","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3396637","text":"We further identified abundant TE families in each species and have several significant observations (Fig. 2). First, there are near-linear distributions of MIR in introns with a length range of 150 bp–10,000 bp and rapid accumulations of introns over 10,000 bp in the primate and large mammal lineages. In contrast, there is a drastic slowing-down in the rodents, particularly mouse and rat. Aside from this, slowing gains of MIR are also seen in the two primitive mammals. Second, the trends of L1 and L2 insertions over intron sizes are also interesting; the two curves intersect in the large mammals and primates but do not in opossum, where we observe L1 \u003c L2 before and L1 \u003e L2 after the intersections. Third, the distribution of primate-specific Alu repeats has an up-convex curvature, an indication of early saturation and preferred insertions in relatively small introns as compared to LINEs and other SINEs. The rodent-specific B1, in contrast, has a near-linear distribution and is more prevalent than B2 and B4. SINE:ID, unique to mouse and rat, seems more active in rat than in mouse. Fourth, distinctly different from what in other mammals, L2 in platypus behaves similarly to its MIR.","tracks":[]}