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PMC:3359311 / 9900-10426 JSONTXT

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bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T13623 106-115 Protein denotes caspase-1
T13624 93-102 Positive_regulation denotes increases
R12095 T13623 T13624 themeOf caspase-1,increases

GO-CC

Id Subject Object Predicate Lexical cue
T13622 464-469 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T13509 44-49 NNS denotes PBMCs
T13510 50-54 IN denotes from
T13511 55-57 NNP denotes CF
T13512 58-66 NNS denotes patients
T13513 67-70 CC denotes and
T13514 71-79 NNS denotes controls
T13515 80-84 VBP denotes show
T13516 85-92 JJ denotes similar
T13517 93-102 NNS denotes increases
T13518 103-105 IN denotes in
T13519 106-115 JJ denotes caspase-1
T13520 116-124 NN denotes activity
T13521 125-129 IN denotes upon
T13522 130-142 JJ denotes inflammasome
T13523 143-153 NN denotes activation
T13524 153-154 . denotes .
T13525 155-160 NNS denotes PBMCs
T13526 161-165 IN denotes from
T13527 166-168 NNP denotes CF
T13528 169-177 NNS denotes patients
T13529 178-179 -LRB- denotes (
T13530 179-180 FW denotes n
T13531 181-182 SYM denotes =
T13532 183-184 CD denotes 6
T13533 184-185 -RRB- denotes )
T13534 186-189 CC denotes and
T13535 190-197 JJ denotes healthy
T13536 198-206 NNS denotes controls
T13537 207-208 -LRB- denotes (
T13538 208-209 FW denotes n
T13539 210-211 SYM denotes =
T13540 212-213 CD denotes 6
T13541 213-214 -RRB- denotes )
T13542 215-219 VBD denotes were
T13543 220-226 VBN denotes primed
T13544 227-231 IN denotes with
T13545 232-235 NNP denotes LPS
T13546 236-237 -LRB- denotes (
T13547 237-239 CD denotes 10
T13548 240-245 NN denotes ng/ml
T13549 245-246 -RRB- denotes )
T13550 247-250 IN denotes for
T13551 251-252 CD denotes 5
T13552 253-258 NNS denotes hours
T13553 259-264 RB denotes prior
T13554 265-267 TO denotes to
T13555 268-279 NN denotes stimulation
T13556 280-284 IN denotes with
T13557 285-288 NNP denotes ATP
T13558 289-290 -LRB- denotes (
T13559 290-291 CD denotes 5
T13560 292-294 NNP denotes mM
T13561 294-295 -RRB- denotes )
T13562 296-299 IN denotes for
T13563 300-301 CD denotes 1
T13564 302-306 NN denotes hour
T13565 307-309 CC denotes or
T13566 310-314 NNP denotes Poly
T13567 314-315 -LRB- denotes (
T13568 315-317 NNP denotes dA
T13569 317-318 : denotes :
T13570 318-320 NN denotes dT
T13571 320-321 -RRB- denotes )
T13572 322-323 -LRB- denotes (
T13573 323-324 CD denotes 1
T13574 325-327 NN denotes µg
T13575 327-328 NN denotes /
T13576 328-330 NN denotes ml
T13577 330-331 -RRB- denotes )
T13578 332-335 IN denotes for
T13579 336-337 CD denotes 3
T13580 338-343 NNS denotes hours
T13581 343-344 . denotes .
T13582 345-350 NNS denotes PBMCs
T13583 351-355 VBD denotes were
T13584 356-366 VBN denotes stimulated
T13585 367-371 IN denotes with
T13586 372-374 NNP denotes P.
T13587 375-385 NN denotes aeruginosa
T13588 386-392 NN denotes strain
T13589 393-397 NNP denotes PAO1
T13590 398-401 IN denotes for
T13591 402-403 CD denotes 3
T13592 404-409 NNS denotes hours
T13593 409-410 . denotes .
T13594 411-412 DT denotes A
T13595 413-427 JJ denotes representative
T13596 428-437 NN denotes histogram
T13597 438-440 IN denotes of
T13598 441-444 DT denotes the
T13599 445-446 NN denotes %
T13600 447-463 JJ denotes caspase-1-active
T13601 464-469 NNS denotes cells
T13602 470-472 VBZ denotes is
T13603 473-478 VBN denotes shown
T13604 479-481 IN denotes in
T13605 482-483 -LRB- denotes (
T13606 483-484 NN denotes A
T13607 484-485 -RRB- denotes )
T13608 486-490 IN denotes with
T13609 491-494 DT denotes the
T13610 495-503 VBN denotes averaged
T13611 504-510 NNS denotes values
T13612 511-516 VBN denotes shown
T13613 517-519 IN denotes in
T13614 520-521 -LRB- denotes (
T13615 521-522 NNP denotes B
T13616 522-523 -RRB- denotes )
T13617 523-524 . denotes .
R11986 T13509 T13515 nsubj PBMCs,show
R11987 T13510 T13509 prep from,PBMCs
R11988 T13511 T13512 compound CF,patients
R11989 T13512 T13510 pobj patients,from
R11990 T13513 T13512 cc and,patients
R11991 T13514 T13512 conj controls,patients
R11992 T13515 T13515 ROOT show,show
R11993 T13516 T13517 amod similar,increases
R11994 T13517 T13515 dobj increases,show
R11995 T13518 T13517 prep in,increases
R11996 T13519 T13520 amod caspase-1,activity
R11997 T13520 T13518 pobj activity,in
R11998 T13521 T13517 prep upon,increases
R11999 T13522 T13523 amod inflammasome,activation
R12000 T13523 T13521 pobj activation,upon
R12001 T13524 T13515 punct .,show
R12002 T13525 T13543 nsubjpass PBMCs,primed
R12003 T13526 T13525 prep from,PBMCs
R12004 T13527 T13528 compound CF,patients
R12005 T13528 T13526 pobj patients,from
R12006 T13529 T13528 punct (,patients
R12007 T13530 T13543 nsubjpass n,primed
R12008 T13531 T13532 punct =,6
R12009 T13532 T13530 prep 6,n
R12010 T13533 T13530 punct ),n
R12011 T13534 T13530 cc and,n
R12012 T13535 T13536 amod healthy,controls
R12013 T13536 T13530 conj controls,n
R12014 T13537 T13540 punct (,6
R12015 T13538 T13540 advmod n,6
R12016 T13539 T13540 punct =,6
R12017 T13540 T13536 appos 6,controls
R12018 T13541 T13536 punct ),controls
R12019 T13542 T13543 auxpass were,primed
R12020 T13543 T13543 ROOT primed,primed
R12021 T13544 T13543 prep with,primed
R12022 T13545 T13544 pobj LPS,with
R12023 T13546 T13545 punct (,LPS
R12024 T13547 T13548 nummod 10,ng/ml
R12025 T13548 T13545 appos ng/ml,LPS
R12026 T13549 T13545 punct ),LPS
R12027 T13550 T13543 prep for,primed
R12028 T13551 T13552 nummod 5,hours
R12029 T13552 T13550 pobj hours,for
R12030 T13553 T13543 advmod prior,primed
R12031 T13554 T13553 prep to,prior
R12032 T13555 T13554 pobj stimulation,to
R12033 T13556 T13543 prep with,primed
R12034 T13557 T13556 pobj ATP,with
R12035 T13558 T13557 punct (,ATP
R12036 T13559 T13560 nummod 5,mM
R12037 T13560 T13557 appos mM,ATP
R12038 T13561 T13557 punct ),ATP
R12039 T13562 T13543 prep for,primed
R12040 T13563 T13564 nummod 1,hour
R12041 T13564 T13562 pobj hour,for
R12042 T13565 T13564 cc or,hour
R12043 T13566 T13564 conj Poly,hour
R12044 T13567 T13566 punct (,Poly
R12045 T13568 T13566 nmod dA,Poly
R12046 T13569 T13566 punct :,Poly
R12047 T13570 T13566 appos dT,Poly
R12048 T13571 T13566 punct ),Poly
R12049 T13572 T13576 punct (,ml
R12050 T13573 T13574 nummod 1,µg
R12051 T13574 T13576 nmod µg,ml
R12052 T13575 T13576 compound /,ml
R12053 T13576 T13566 appos ml,Poly
R12054 T13577 T13543 punct ),primed
R12055 T13578 T13543 prep for,primed
R12056 T13579 T13580 nummod 3,hours
R12057 T13580 T13578 pobj hours,for
R12058 T13581 T13543 punct .,primed
R12059 T13582 T13584 nsubjpass PBMCs,stimulated
R12060 T13583 T13584 auxpass were,stimulated
R12061 T13584 T13584 ROOT stimulated,stimulated
R12062 T13585 T13584 prep with,stimulated
R12063 T13586 T13588 nsubj P.,strain
R12064 T13587 T13588 compound aeruginosa,strain
R12065 T13588 T13585 pobj strain,with
R12066 T13589 T13588 appos PAO1,strain
R12067 T13590 T13584 prep for,stimulated
R12068 T13591 T13592 nummod 3,hours
R12069 T13592 T13590 pobj hours,for
R12070 T13593 T13584 punct .,stimulated
R12071 T13594 T13596 det A,histogram
R12072 T13595 T13596 amod representative,histogram
R12073 T13596 T13603 nsubjpass histogram,shown
R12074 T13597 T13596 prep of,histogram
R12075 T13598 T13601 det the,cells
R12076 T13599 T13601 nmod %,cells
R12077 T13600 T13601 amod caspase-1-active,cells
R12078 T13601 T13597 pobj cells,of
R12079 T13602 T13603 auxpass is,shown
R12080 T13603 T13603 ROOT shown,shown
R12081 T13604 T13603 prep in,shown
R12082 T13605 T13606 punct (,A
R12083 T13606 T13604 pobj A,in
R12084 T13607 T13606 punct ),A
R12085 T13608 T13603 prep with,shown
R12086 T13609 T13611 det the,values
R12087 T13610 T13611 amod averaged,values
R12088 T13611 T13608 pobj values,with
R12089 T13612 T13611 acl shown,values
R12090 T13613 T13612 prep in,shown
R12091 T13614 T13615 punct (,B
R12092 T13615 T13613 pobj B,in
R12093 T13616 T13603 punct ),shown
R12094 T13617 T13603 punct .,shown

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T13410 44-49 NN denotes PBMCs
T13411 50-54 IN denotes from
T13412 55-57 NN denotes CF
T13413 58-66 NN denotes patients
T13414 67-70 CC denotes and
T13415 71-79 NN denotes controls
T13416 80-84 VB denotes show
T13417 85-92 JJ denotes similar
T13418 93-102 NN denotes increases
T13419 103-105 IN denotes in
T13420 106-115 NN denotes caspase-1
T13421 116-124 NN denotes activity
T13422 125-129 IN denotes upon
T13423 130-142 JJ denotes inflammasome
T13424 143-153 NN denotes activation
T13425 155-160 NN denotes PBMCs
T13426 161-165 IN denotes from
T13427 166-168 NN denotes CF
T13428 169-177 NN denotes patients
T13429 178-179 -LRB- denotes (
T13430 179-184 NN denotes n = 6
T13431 184-185 -RRB- denotes )
T13432 186-189 CC denotes and
T13433 190-197 JJ denotes healthy
T13434 198-206 NN denotes controls
T13435 207-208 -LRB- denotes (
T13436 208-213 NN denotes n = 6
T13437 213-214 -RRB- denotes )
T13438 215-219 VB denotes were
T13439 220-226 VB denotes primed
T13440 227-231 IN denotes with
T13441 232-235 NN denotes LPS
T13442 236-237 -LRB- denotes (
T13443 237-239 CD denotes 10
T13444 240-245 NN denotes ng/ml
T13445 245-246 -RRB- denotes )
T13446 247-250 IN denotes for
T13447 251-252 CD denotes 5
T13448 253-258 NN denotes hours
T13449 259-264 RB denotes prior
T13450 265-267 TO denotes to
T13451 268-279 NN denotes stimulation
T13452 280-284 IN denotes with
T13453 285-288 NN denotes ATP
T13454 289-290 -LRB- denotes (
T13455 290-291 CD denotes 5
T13456 292-294 NN denotes mM
T13457 294-295 -RRB- denotes )
T13458 296-299 IN denotes for
T13459 300-301 CD denotes 1
T13460 302-306 NN denotes hour
T13461 307-309 CC denotes or
T13462 310-314 NN denotes Poly
T13463 314-315 -LRB- denotes (
T13464 315-317 NN denotes dA
T13465 317-318 -COLON- denotes :
T13466 318-320 NN denotes dT
T13467 320-321 -RRB- denotes )
T13468 322-323 -LRB- denotes (
T13469 323-324 CD denotes 1
T13470 325-330 NN denotes µg/ml
T13471 330-331 -RRB- denotes )
T13472 332-335 IN denotes for
T13473 336-337 CD denotes 3
T13474 338-343 NN denotes hours
T13475 345-350 NN denotes PBMCs
T13476 351-355 VB denotes were
T13477 356-366 VB denotes stimulated
T13478 367-371 IN denotes with
T13479 372-374 NNP denotes P.
T13480 375-385 NN denotes aeruginosa
T13481 386-392 NN denotes strain
T13482 393-397 NN denotes PAO1
T13483 398-401 IN denotes for
T13484 402-403 CD denotes 3
T13485 404-409 NN denotes hours
T13486 411-412 DT denotes A
T13487 413-427 JJ denotes representative
T13488 428-437 NN denotes histogram
T13489 438-440 IN denotes of
T13490 441-444 DT denotes the
T13491 445-446 NN denotes %
T13492 447-463 JJ denotes caspase-1-active
T13493 464-469 NN denotes cells
T13494 470-472 VB denotes is
T13495 473-478 VB denotes shown
T13496 479-481 IN denotes in
T13497 482-483 -LRB- denotes (
T13498 483-484 NN denotes A
T13499 484-485 -RRB- denotes )
T13500 486-490 IN denotes with
T13501 491-494 DT denotes the
T13502 495-503 JJ denotes averaged
T13503 504-510 NN denotes values
T13504 511-516 VB denotes shown
T13505 517-519 IN denotes in
T13506 520-521 -LRB- denotes (
T13507 521-522 NN denotes B
T13508 522-523 -RRB- denotes )
R11888 T13410 T13411 arg1Of PBMCs,from
R11889 T13410 T13416 arg1Of PBMCs,show
R11890 T13413 T13412 arg1Of patients,CF
R11891 T13413 T13414 arg1Of patients,and
R11892 T13414 T13411 arg2Of and,from
R11893 T13415 T13414 arg2Of controls,and
R11894 T13418 T13416 arg2Of increases,show
R11895 T13418 T13417 arg1Of increases,similar
R11896 T13418 T13419 arg1Of increases,in
R11897 T13421 T13419 arg2Of activity,in
R11898 T13421 T13420 arg1Of activity,caspase-1
R11899 T13421 T13422 arg1Of activity,upon
R11900 T13424 T13422 arg2Of activation,upon
R11901 T13424 T13423 arg1Of activation,inflammasome
R11902 T13425 T13426 arg1Of PBMCs,from
R11903 T13425 T13438 arg1Of PBMCs,were
R11904 T13425 T13439 arg2Of PBMCs,primed
R11905 T13428 T13427 arg1Of patients,CF
R11906 T13428 T13429 arg1Of patients,(
R11907 T13428 T13432 arg1Of patients,and
R11908 T13430 T13429 arg2Of n = 6,(
R11909 T13431 T13429 arg3Of ),(
R11910 T13432 T13426 arg2Of and,from
R11911 T13434 T13432 arg2Of controls,and
R11912 T13434 T13433 arg1Of controls,healthy
R11913 T13434 T13435 arg1Of controls,(
R11914 T13436 T13435 arg2Of n = 6,(
R11915 T13437 T13435 arg3Of ),(
R11916 T13439 T13438 arg2Of primed,were
R11917 T13439 T13440 arg1Of primed,with
R11918 T13439 T13446 arg1Of primed,for
R11919 T13439 T13472 arg1Of primed,for
R11920 T13441 T13440 arg2Of LPS,with
R11921 T13441 T13442 arg1Of LPS,(
R11922 T13444 T13442 arg2Of ng/ml,(
R11923 T13444 T13443 arg1Of ng/ml,10
R11924 T13445 T13442 arg3Of ),(
R11925 T13448 T13446 arg2Of hours,for
R11926 T13448 T13447 arg1Of hours,5
R11927 T13449 T13450 arg1Of prior,to
R11928 T13451 T13452 arg1Of stimulation,with
R11929 T13451 T13461 arg1Of stimulation,or
R11930 T13453 T13452 arg2Of ATP,with
R11931 T13453 T13454 arg1Of ATP,(
R11932 T13453 T13458 arg1Of ATP,for
R11933 T13456 T13454 arg2Of mM,(
R11934 T13456 T13455 arg1Of mM,5
R11935 T13457 T13454 arg3Of ),(
R11936 T13460 T13458 arg2Of hour,for
R11937 T13460 T13459 arg1Of hour,1
R11938 T13461 T13450 arg2Of or,to
R11939 T13462 T13461 arg2Of Poly,or
R11940 T13462 T13463 arg1Of Poly,(
R11941 T13462 T13468 arg1Of Poly,(
R11942 T13464 T13463 arg2Of dA,(
R11943 T13464 T13465 arg1Of dA,:
R11944 T13464 T13466 arg1Of dA,dT
R11945 T13467 T13463 arg3Of ),(
R11946 T13470 T13468 arg2Of µg/ml,(
R11947 T13470 T13469 arg1Of µg/ml,1
R11948 T13471 T13468 arg3Of ),(
R11949 T13472 T13449 arg1Of for,prior
R11950 T13474 T13472 arg2Of hours,for
R11951 T13474 T13473 arg1Of hours,3
R11952 T13475 T13476 arg1Of PBMCs,were
R11953 T13475 T13477 arg2Of PBMCs,stimulated
R11954 T13477 T13476 arg2Of stimulated,were
R11955 T13477 T13478 arg1Of stimulated,with
R11956 T13482 T13478 arg2Of PAO1,with
R11957 T13482 T13479 arg1Of PAO1,P.
R11958 T13482 T13480 arg1Of PAO1,aeruginosa
R11959 T13482 T13481 arg1Of PAO1,strain
R11960 T13482 T13483 arg1Of PAO1,for
R11961 T13485 T13483 arg2Of hours,for
R11962 T13485 T13484 arg1Of hours,3
R11963 T13488 T13486 arg1Of histogram,A
R11964 T13488 T13487 arg1Of histogram,representative
R11965 T13488 T13489 arg1Of histogram,of
R11966 T13488 T13494 arg1Of histogram,is
R11967 T13488 T13495 arg2Of histogram,shown
R11968 T13493 T13489 arg2Of cells,of
R11969 T13493 T13490 arg1Of cells,the
R11970 T13493 T13491 arg1Of cells,%
R11971 T13493 T13492 arg1Of cells,caspase-1-active
R11972 T13495 T13494 arg2Of shown,is
R11973 T13495 T13496 arg1Of shown,in
R11974 T13498 T13496 arg2Of A,in
R11975 T13498 T13497 arg2Of A,(
R11976 T13498 T13500 arg1Of A,with
R11977 T13499 T13497 arg3Of ),(
R11978 T13503 T13500 arg2Of values,with
R11979 T13503 T13501 arg1Of values,the
R11980 T13503 T13502 arg1Of values,averaged
R11981 T13503 T13504 arg2Of values,shown
R11982 T13504 T13505 arg1Of shown,in
R11983 T13507 T13505 arg2Of B,in
R11984 T13507 T13506 arg2Of B,(
R11985 T13508 T13506 arg3Of ),(

sentences

Id Subject Object Predicate Lexical cue
T13406 44-154 Sentence denotes PBMCs from CF patients and controls show similar increases in caspase-1 activity upon inflammasome activation.
T13407 155-344 Sentence denotes PBMCs from CF patients (n = 6) and healthy controls (n = 6) were primed with LPS (10 ng/ml) for 5 hours prior to stimulation with ATP (5 mM) for 1 hour or Poly(dA:dT) (1 µg/ml) for 3 hours.
T13408 345-410 Sentence denotes PBMCs were stimulated with P. aeruginosa strain PAO1 for 3 hours.
T13409 411-524 Sentence denotes A representative histogram of the % caspase-1-active cells is shown in (A) with the averaged values shown in (B).
T72 0-154 Sentence denotes 10.1371/journal.pone.0037689.g004 Figure 4 PBMCs from CF patients and controls show similar increases in caspase-1 activity upon inflammasome activation.
T73 155-344 Sentence denotes PBMCs from CF patients (n = 6) and healthy controls (n = 6) were primed with LPS (10 ng/ml) for 5 hours prior to stimulation with ATP (5 mM) for 1 hour or Poly(dA:dT) (1 µg/ml) for 3 hours.
T74 345-410 Sentence denotes PBMCs were stimulated with P. aeruginosa strain PAO1 for 3 hours.
T75 411-524 Sentence denotes A representative histogram of the % caspase-1-active cells is shown in (A) with the averaged values shown in (B).