PMC:3359311 / 7936-9426
Annnotations
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3212 | 562-566 | P05231 | denotes | IL-6 |
| T3213 | 691-695 | P05231 | denotes | IL-6 |
| T13245 | 1465-1469 | P05231 | denotes | IL-6 |
bionlp-st-ge-2016-reference
| Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
|---|---|---|---|---|---|---|
| T3082 | 538-545 | Regulation | denotes | altered | true | |
| T3083 | 552-561 | Regulation | denotes | dependent | ||
| T3084 | 562-566 | Protein | denotes | IL-6 | ||
| T3085 | 567-577 | Gene_expression | denotes | production | ||
| T3086 | 578-592 | Positive_regulation | denotes | in response to | ||
| T3087 | 682-690 | Negative_regulation | denotes | decrease | true | |
| T3088 | 691-695 | Protein | denotes | IL-6 | ||
| T3089 | 696-705 | Localization | denotes | secretion | ||
| T13115 | 1465-1469 | Protein | denotes | IL-6 | ||
| R2665 | T3083 | T3086 | themeOf | dependent,in response to | ||
| R2666 | T3084 | T3085 | themeOf | IL-6,production | ||
| R2667 | T3085 | T3083 | themeOf | production,dependent | ||
| R2668 | T3086 | T3082 | themeOf | in response to,altered | ||
| R2669 | T3088 | T3089 | themeOf | IL-6,secretion | ||
| R2670 | T3089 | T3087 | themeOf | secretion,decrease |
bionlp-st-ge-2016-reference-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3378 | 56-65 | Protein | denotes | caspase-1 |
| T3379 | 45-55 | Positive_regulation | denotes | upregulate |
| T3380 | 183-192 | Protein | denotes | caspase-1 |
| T3381 | 399-408 | Protein | denotes | caspase-1 |
| T3382 | 430-435 | Protein | denotes | NF-κB |
| T3383 | 444-462 | Protein | denotes | Toll-like receptor |
| T3384 | 464-467 | Protein | denotes | TLR |
| T3385 | 528-537 | Protein | denotes | caspase-1 |
| T3386 | 546-551 | Protein | denotes | NF-κB |
| T3387 | 562-566 | Protein | denotes | IL-6 |
| T3388 | 416-426 | Positive_regulation | denotes | activation |
| T3389 | 514-524 | Negative_regulation | denotes | inhibition |
| T3390 | 567-577 | Gene_expression | denotes | production |
| T3391 | 390-394 | Regulation | denotes | role |
| T3392 | 538-545 | Positive_regulation | denotes | altered |
| T3393 | 552-561 | Positive_regulation | denotes | dependent |
| T3394 | 636-645 | Protein | denotes | caspase-1 |
| T3395 | 691-695 | Protein | denotes | IL-6 |
| T3396 | 734-741 | Protein | denotes | Fig. 3c |
| T3397 | 696-705 | Localization | denotes | secretion |
| T3398 | 682-690 | Negative_regulation | denotes | decrease |
| T13403 | 828-837 | Protein | denotes | caspase-1 |
| T13404 | 817-827 | Positive_regulation | denotes | upregulate |
| T13405 | 1465-1469 | Protein | denotes | IL-6 |
| R2927 | T3378 | T3379 | themeOf | caspase-1,upregulate |
| R2928 | T3381 | T3391 | causeOf | caspase-1,role |
| R2929 | T3382 | T3388 | themeOf | NF-κB,activation |
| R2930 | T3385 | T3389 | themeOf | caspase-1,inhibition |
| R2931 | T3386 | T3393 | causeOf | NF-κB,dependent |
| R2932 | T3387 | T3390 | themeOf | IL-6,production |
| R2933 | T3388 | T3391 | themeOf | activation,role |
| R2934 | T3390 | T3392 | themeOf | production,altered |
| R2935 | T3390 | T3393 | themeOf | production,dependent |
| R2936 | T3395 | T3397 | themeOf | IL-6,secretion |
| R2937 | T3397 | T3398 | themeOf | secretion,decrease |
| R11887 | T13403 | T13404 | themeOf | caspase-1,upregulate |
events-check-again
| Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
|---|---|---|---|---|---|---|
| T3370 | 538-545 | Regulation | denotes | altered | true | |
| T3371 | 552-561 | Regulation | denotes | dependent | ||
| T3372 | 562-566 | Protein | denotes | IL-6 | ||
| T3373 | 567-577 | Gene_expression | denotes | production | ||
| T3374 | 578-592 | Positive_regulation | denotes | in response to | ||
| T3375 | 682-690 | Negative_regulation | denotes | decrease | true | |
| T3376 | 691-695 | Protein | denotes | IL-6 | ||
| T3377 | 696-705 | Localization | denotes | secretion | ||
| T13402 | 1465-1469 | Protein | denotes | IL-6 | ||
| R2921 | T3371 | T3374 | themeOf | dependent,in response to | ||
| R2922 | T3372 | T3373 | themeOf | IL-6,production | ||
| R2923 | T3373 | T3371 | themeOf | production,dependent | ||
| R2924 | T3374 | T3370 | themeOf | in response to,altered | ||
| R2925 | T3376 | T3377 | themeOf | IL-6,secretion | ||
| R2926 | T3377 | T3375 | themeOf | secretion,decrease |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3349 | 18-23 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3350 | 176-181 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3351 | 727-732 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T13394 | 795-800 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T13395 | 897-902 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T13396 | 1130-1135 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T13397 | 1233-1238 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T13398 | 1246-1251 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T13399 | 1394-1398 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cell |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3352 | 562-566 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T3353 | 691-695 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T13393 | 1465-1469 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3341 | 66-86 | http://purl.obolibrary.org/obo/GO_0014823 | denotes | activity in response |
| T3342 | 416-435 | http://purl.obolibrary.org/obo/GO_0051092 | denotes | activation of NF-κB |
| T3343 | 469-478 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T3344 | 562-577 | http://purl.obolibrary.org/obo/GO_0032635 | denotes | IL-6 production |
| T3345 | 562-577 | http://purl.obolibrary.org/obo/GO_0032675 | denotes | IL-6 production |
| T3346 | 691-705 | http://purl.obolibrary.org/obo/GO_1900165 | denotes | IL-6 secretion |
| T3347 | 691-705 | http://purl.obolibrary.org/obo/GO_0072604 | denotes | IL-6 secretion |
| T3348 | 696-705 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T13392 | 838-858 | http://purl.obolibrary.org/obo/GO_0014823 | denotes | activity in response |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3214 | 0-6 | NNP | denotes | Airway |
| T3215 | 7-17 | JJ | denotes | epithelial |
| T3216 | 18-23 | NNS | denotes | cells |
| T3217 | 24-26 | VBP | denotes | do |
| T3218 | 27-30 | RB | denotes | not |
| T3219 | 31-44 | RB | denotes | significantly |
| T3220 | 45-55 | VB | denotes | upregulate |
| T3221 | 56-65 | JJ | denotes | caspase-1 |
| T3222 | 66-74 | NN | denotes | activity |
| T3223 | 75-77 | IN | denotes | in |
| T3224 | 78-86 | NN | denotes | response |
| T3225 | 87-89 | TO | denotes | to |
| T3226 | 90-102 | JJ | denotes | inflammasome |
| T3227 | 103-114 | NN | denotes | stimulation |
| T3228 | 115-117 | TO | denotes | To |
| T3229 | 118-125 | VB | denotes | examine |
| T3230 | 126-128 | IN | denotes | if |
| T3231 | 129-141 | JJ | denotes | inflammasome |
| T3232 | 142-152 | NN | denotes | activation |
| T3233 | 153-159 | VBZ | denotes | occurs |
| T3234 | 160-162 | IN | denotes | in |
| T3235 | 163-168 | DT | denotes | these |
| T3236 | 169-175 | NN | denotes | airway |
| T3237 | 176-181 | NNS | denotes | cells |
| T3238 | 181-182 | , | denotes | , |
| T3239 | 183-192 | JJ | denotes | caspase-1 |
| T3240 | 193-201 | NN | denotes | activity |
| T3241 | 202-205 | VBD | denotes | was |
| T3242 | 206-216 | VBN | denotes | quantified |
| T3243 | 217-219 | IN | denotes | by |
| T3244 | 220-224 | NN | denotes | flow |
| T3245 | 225-234 | NN | denotes | cytometry |
| T3246 | 234-235 | . | denotes | . |
| T3247 | 236-241 | EX | denotes | There |
| T3248 | 242-245 | VBD | denotes | was |
| T3249 | 246-248 | DT | denotes | no |
| T3250 | 249-260 | JJ | denotes | significant |
| T3251 | 261-269 | NN | denotes | increase |
| T3252 | 270-274 | IN | denotes | upon |
| T3253 | 275-286 | NN | denotes | stimulation |
| T3254 | 287-291 | IN | denotes | with |
| T3255 | 292-296 | JJ | denotes | live |
| T3256 | 297-301 | CD | denotes | PAO1 |
| T3257 | 302-304 | CC | denotes | or |
| T3258 | 305-312 | NNP | denotes | LPS+ATP |
| T3259 | 313-315 | IN | denotes | at |
| T3260 | 316-319 | DT | denotes | the |
| T3261 | 320-325 | NNS | denotes | times |
| T3262 | 326-334 | VBD | denotes | examined |
| T3263 | 335-336 | -LRB- | denotes | ( |
| T3264 | 336-340 | NNP | denotes | Fig. |
| T3265 | 341-343 | CD | denotes | 3a |
| T3266 | 344-345 | NN | denotes | b |
| T3267 | 345-346 | -RRB- | denotes | ) |
| T3268 | 346-347 | . | denotes | . |
| T3269 | 348-355 | IN | denotes | Because |
| T3270 | 356-364 | JJ | denotes | previous |
| T3271 | 365-372 | NNS | denotes | studies |
| T3272 | 373-377 | VBP | denotes | have |
| T3273 | 378-387 | VBN | denotes | indicated |
| T3274 | 388-389 | DT | denotes | a |
| T3275 | 390-394 | NN | denotes | role |
| T3276 | 395-398 | IN | denotes | for |
| T3277 | 399-408 | JJ | denotes | caspase-1 |
| T3278 | 409-411 | IN | denotes | in |
| T3279 | 412-415 | DT | denotes | the |
| T3280 | 416-426 | NN | denotes | activation |
| T3281 | 427-429 | IN | denotes | of |
| T3282 | 430-435 | NN | denotes | NF-κB |
| T3283 | 436-443 | IN | denotes | through |
| T3284 | 444-453 | JJ | denotes | Toll-like |
| T3285 | 454-462 | NN | denotes | receptor |
| T3286 | 463-464 | -LRB- | denotes | ( |
| T3287 | 464-467 | NNP | denotes | TLR |
| T3288 | 467-468 | -RRB- | denotes | ) |
| T3289 | 469-478 | VBG | denotes | signaling |
| T3290 | 479-480 | NNP | denotes | [ |
| T3291 | 480-482 | CD | denotes | 35 |
| T3292 | 482-483 | NNP | denotes | ] |
| T3293 | 483-484 | , | denotes | , |
| T3294 | 485-487 | PRP | denotes | we |
| T3295 | 488-496 | VBD | denotes | examined |
| T3296 | 497-504 | IN | denotes | whether |
| T3297 | 505-513 | NN | denotes | chemical |
| T3298 | 514-524 | NN | denotes | inhibition |
| T3299 | 525-527 | IN | denotes | of |
| T3300 | 528-537 | JJ | denotes | caspase-1 |
| T3301 | 538-545 | JJ | denotes | altered |
| T3302 | 546-561 | JJ | denotes | NF-κB-dependent |
| T3303 | 562-566 | NN | denotes | IL-6 |
| T3304 | 567-577 | NN | denotes | production |
| T3305 | 578-580 | IN | denotes | in |
| T3306 | 581-589 | NN | denotes | response |
| T3307 | 590-592 | TO | denotes | to |
| T3308 | 593-595 | NNP | denotes | P. |
| T3309 | 596-606 | NN | denotes | aeruginosa |
| T3310 | 606-607 | . | denotes | . |
| T3311 | 608-615 | RB | denotes | However |
| T3312 | 615-616 | , | denotes | , |
| T3313 | 617-626 | NN | denotes | treatment |
| T3314 | 627-631 | IN | denotes | with |
| T3315 | 632-635 | DT | denotes | the |
| T3316 | 636-645 | JJ | denotes | caspase-1 |
| T3317 | 646-655 | NN | denotes | inhibitor |
| T3318 | 656-666 | NNP | denotes | z-YVAD-fmk |
| T3319 | 667-668 | -LRB- | denotes | ( |
| T3320 | 668-672 | NNP | denotes | YVAD |
| T3321 | 672-673 | -RRB- | denotes | ) |
| T3322 | 674-677 | VBD | denotes | did |
| T3323 | 678-681 | RB | denotes | not |
| T3324 | 682-690 | VB | denotes | decrease |
| T3325 | 691-695 | NNP | denotes | IL-6 |
| T3326 | 696-705 | NN | denotes | secretion |
| T3327 | 706-708 | IN | denotes | by |
| T3328 | 709-715 | NN | denotes | airway |
| T3329 | 716-726 | JJ | denotes | epithelial |
| T3330 | 727-732 | NNS | denotes | cells |
| T3331 | 733-734 | -LRB- | denotes | ( |
| T3332 | 734-738 | NNP | denotes | Fig. |
| T3333 | 739-741 | CD | denotes | 3c |
| T3334 | 741-742 | -RRB- | denotes | ) |
| T3335 | 742-743 | . | denotes | . |
| T13246 | 788-794 | NNP | denotes | Airway |
| T13247 | 795-800 | NNS | denotes | cells |
| T13248 | 801-803 | VBP | denotes | do |
| T13249 | 804-807 | RB | denotes | not |
| T13250 | 808-816 | RB | denotes | strongly |
| T13251 | 817-827 | VB | denotes | upregulate |
| T13252 | 828-837 | JJ | denotes | caspase-1 |
| T13253 | 838-846 | NN | denotes | activity |
| T13254 | 847-849 | IN | denotes | in |
| T13255 | 850-858 | NN | denotes | response |
| T13256 | 859-861 | TO | denotes | to |
| T13257 | 862-874 | JJ | denotes | inflammasome |
| T13258 | 875-882 | NNS | denotes | stimuli |
| T13259 | 882-883 | . | denotes | . |
| T13260 | 884-886 | CD | denotes | S9 |
| T13261 | 887-890 | CC | denotes | and |
| T13262 | 891-896 | CD | denotes | IB3-1 |
| T13263 | 897-902 | NNS | denotes | cells |
| T13264 | 903-907 | VBD | denotes | were |
| T13265 | 908-916 | VBN | denotes | examined |
| T13266 | 917-920 | IN | denotes | for |
| T13267 | 921-930 | JJ | denotes | caspase-1 |
| T13268 | 931-941 | NN | denotes | activation |
| T13269 | 942-951 | VBG | denotes | following |
| T13270 | 952-964 | JJ | denotes | inflammasome |
| T13271 | 965-976 | NN | denotes | stimulation |
| T13272 | 977-981 | IN | denotes | with |
| T13273 | 982-984 | NNP | denotes | P. |
| T13274 | 985-995 | NN | denotes | aeruginosa |
| T13275 | 996-997 | -LRB- | denotes | ( |
| T13276 | 997-1000 | NNP | denotes | MOI |
| T13277 | 1001-1002 | SYM | denotes | = |
| T13278 | 1003-1005 | CD | denotes | 10 |
| T13279 | 1005-1006 | -RRB- | denotes | ) |
| T13280 | 1007-1010 | CC | denotes | and |
| T13281 | 1011-1014 | NNP | denotes | ATP |
| T13282 | 1015-1016 | -LRB- | denotes | ( |
| T13283 | 1016-1017 | CD | denotes | 5 |
| T13284 | 1018-1020 | NNP | denotes | mM |
| T13285 | 1020-1021 | -RRB- | denotes | ) |
| T13286 | 1021-1022 | . | denotes | . |
| T13287 | 1023-1028 | NNS | denotes | Cells |
| T13288 | 1029-1033 | VBD | denotes | were |
| T13289 | 1034-1040 | VBN | denotes | primed |
| T13290 | 1041-1045 | IN | denotes | with |
| T13291 | 1046-1049 | NNP | denotes | LPS |
| T13292 | 1050-1053 | IN | denotes | for |
| T13293 | 1054-1055 | CD | denotes | 5 |
| T13294 | 1056-1061 | NNS | denotes | hours |
| T13295 | 1062-1067 | WRB | denotes | where |
| T13296 | 1068-1079 | JJ | denotes | appropriate |
| T13297 | 1079-1080 | . | denotes | . |
| T13298 | 1081-1082 | DT | denotes | A |
| T13299 | 1083-1097 | JJ | denotes | representative |
| T13300 | 1098-1107 | NN | denotes | histogram |
| T13301 | 1108-1110 | IN | denotes | of |
| T13302 | 1111-1112 | NN | denotes | % |
| T13303 | 1113-1129 | JJ | denotes | caspase-1-active |
| T13304 | 1130-1135 | NNS | denotes | cells |
| T13305 | 1136-1138 | VBZ | denotes | is |
| T13306 | 1139-1144 | VBN | denotes | shown |
| T13307 | 1145-1147 | IN | denotes | in |
| T13308 | 1148-1149 | -LRB- | denotes | ( |
| T13309 | 1149-1150 | NN | denotes | A |
| T13310 | 1150-1151 | -RRB- | denotes | ) |
| T13311 | 1152-1155 | CC | denotes | and |
| T13312 | 1156-1159 | DT | denotes | the |
| T13313 | 1160-1168 | VBD | denotes | averaged |
| T13314 | 1169-1175 | NNS | denotes | values |
| T13315 | 1176-1179 | VBP | denotes | are |
| T13316 | 1180-1185 | VBN | denotes | shown |
| T13317 | 1186-1188 | IN | denotes | in |
| T13318 | 1189-1190 | -LRB- | denotes | ( |
| T13319 | 1190-1191 | NNP | denotes | B |
| T13320 | 1191-1192 | -RRB- | denotes | ) |
| T13321 | 1193-1194 | -LRB- | denotes | ( |
| T13322 | 1194-1195 | FW | denotes | n |
| T13323 | 1196-1197 | SYM | denotes | = |
| T13324 | 1198-1199 | CD | denotes | 3 |
| T13325 | 1200-1208 | JJ | denotes | separate |
| T13326 | 1209-1220 | NNS | denotes | experiments |
| T13327 | 1220-1221 | -RRB- | denotes | ) |
| T13328 | 1221-1222 | . | denotes | . |
| T13329 | 1223-1224 | -LRB- | denotes | ( |
| T13330 | 1224-1225 | $ | denotes | C |
| T13331 | 1225-1226 | -RRB- | denotes | ) |
| T13332 | 1227-1232 | JJ | denotes | IB3-1 |
| T13333 | 1233-1238 | NNS | denotes | cells |
| T13334 | 1239-1240 | -LRB- | denotes | ( |
| T13335 | 1240-1241 | CD | denotes | 5 |
| T13336 | 1241-1242 | CD | denotes | × |
| T13337 | 1242-1245 | CD | denotes | 104 |
| T13338 | 1246-1256 | NN | denotes | cells/well |
| T13339 | 1256-1257 | -RRB- | denotes | ) |
| T13340 | 1258-1262 | VBD | denotes | were |
| T13341 | 1263-1274 | JJ | denotes | pre-treated |
| T13342 | 1275-1278 | IN | denotes | for |
| T13343 | 1279-1280 | CD | denotes | 1 |
| T13344 | 1281-1285 | NN | denotes | hour |
| T13345 | 1286-1290 | IN | denotes | with |
| T13346 | 1291-1301 | VBG | denotes | increasing |
| T13347 | 1302-1316 | NNS | denotes | concentrations |
| T13348 | 1317-1319 | IN | denotes | of |
| T13349 | 1320-1330 | NNP | denotes | z-YVAD-fmk |
| T13350 | 1331-1332 | -LRB- | denotes | ( |
| T13351 | 1332-1334 | CD | denotes | 10 |
| T13352 | 1335-1337 | CD | denotes | 30 |
| T13353 | 1338-1340 | NNP | denotes | µM |
| T13354 | 1340-1341 | -RRB- | denotes | ) |
| T13355 | 1342-1347 | RB | denotes | prior |
| T13356 | 1348-1350 | TO | denotes | to |
| T13357 | 1351-1362 | NN | denotes | stimulation |
| T13358 | 1363-1367 | IN | denotes | with |
| T13359 | 1368-1370 | NNP | denotes | P. |
| T13360 | 1371-1381 | NN | denotes | aeruginosa |
| T13361 | 1382-1383 | -LRB- | denotes | ( |
| T13362 | 1383-1386 | NNP | denotes | MOI |
| T13363 | 1387-1388 | SYM | denotes | = |
| T13364 | 1389-1391 | CD | denotes | 50 |
| T13365 | 1391-1392 | -RRB- | denotes | ) |
| T13366 | 1392-1393 | . | denotes | . |
| T13367 | 1394-1398 | NNP | denotes | Cell |
| T13368 | 1399-1406 | NN | denotes | culture |
| T13369 | 1407-1419 | NNS | denotes | supernatants |
| T13370 | 1420-1424 | VBD | denotes | were |
| T13371 | 1425-1434 | VBN | denotes | collected |
| T13372 | 1435-1440 | IN | denotes | after |
| T13373 | 1441-1442 | CD | denotes | 6 |
| T13374 | 1443-1448 | NNS | denotes | hours |
| T13375 | 1449-1452 | CC | denotes | and |
| T13376 | 1453-1460 | VBN | denotes | assayed |
| T13377 | 1461-1464 | IN | denotes | for |
| T13378 | 1465-1469 | NN | denotes | IL-6 |
| T13379 | 1470-1472 | IN | denotes | by |
| T13380 | 1473-1478 | NNP | denotes | ELISA |
| T13381 | 1479-1480 | -LRB- | denotes | ( |
| T13382 | 1480-1481 | FW | denotes | n |
| T13383 | 1482-1483 | SYM | denotes | = |
| T13384 | 1484-1485 | LS | denotes | 3 |
| T13385 | 1485-1486 | -RRB- | denotes | ) |
| T13386 | 1486-1487 | . | denotes | . |
| R2787 | T3214 | T3216 | nmod | Airway,cells |
| R2788 | T3215 | T3216 | amod | epithelial,cells |
| R2789 | T3216 | T3220 | nsubj | cells,upregulate |
| R2790 | T3217 | T3220 | aux | do,upregulate |
| R2791 | T3218 | T3220 | neg | not,upregulate |
| R2792 | T3219 | T3220 | advmod | significantly,upregulate |
| R2793 | T3220 | T3220 | ROOT | upregulate,upregulate |
| R2794 | T3221 | T3222 | compound | caspase-1,activity |
| R2795 | T3222 | T3220 | dobj | activity,upregulate |
| R2796 | T3223 | T3220 | prep | in,upregulate |
| R2797 | T3224 | T3223 | pobj | response,in |
| R2798 | T3225 | T3224 | prep | to,response |
| R2799 | T3226 | T3227 | amod | inflammasome,stimulation |
| R2800 | T3227 | T3225 | pobj | stimulation,to |
| R2801 | T3228 | T3229 | aux | To,examine |
| R2802 | T3229 | T3220 | advcl | examine,upregulate |
| R2803 | T3230 | T3233 | mark | if,occurs |
| R2804 | T3231 | T3232 | amod | inflammasome,activation |
| R2805 | T3232 | T3233 | nsubj | activation,occurs |
| R2806 | T3233 | T3242 | advcl | occurs,quantified |
| R2807 | T3234 | T3233 | prep | in,occurs |
| R2808 | T3235 | T3237 | det | these,cells |
| R2809 | T3236 | T3237 | compound | airway,cells |
| R2810 | T3237 | T3234 | pobj | cells,in |
| R2811 | T3238 | T3242 | punct | ",",quantified |
| R2812 | T3239 | T3240 | amod | caspase-1,activity |
| R2813 | T3240 | T3242 | nsubjpass | activity,quantified |
| R2814 | T3241 | T3242 | auxpass | was,quantified |
| R2815 | T3242 | T3220 | advcl | quantified,upregulate |
| R2816 | T3243 | T3242 | agent | by,quantified |
| R2817 | T3244 | T3245 | compound | flow,cytometry |
| R2818 | T3245 | T3243 | pobj | cytometry,by |
| R2819 | T3246 | T3242 | punct | .,quantified |
| R2820 | T3247 | T3248 | expl | There,was |
| R2821 | T3248 | T3248 | ROOT | was,was |
| R2822 | T3249 | T3251 | det | no,increase |
| R2823 | T3250 | T3251 | amod | significant,increase |
| R2824 | T3251 | T3248 | attr | increase,was |
| R2825 | T3252 | T3251 | prep | upon,increase |
| R2826 | T3253 | T3252 | pobj | stimulation,upon |
| R2827 | T3254 | T3251 | prep | with,increase |
| R2828 | T3255 | T3256 | amod | live,PAO1 |
| R2829 | T3256 | T3254 | pobj | PAO1,with |
| R2830 | T3257 | T3256 | cc | or,PAO1 |
| R2831 | T3258 | T3256 | conj | LPS+ATP,PAO1 |
| R2832 | T3259 | T3248 | prep | at,was |
| R2833 | T3260 | T3261 | det | the,times |
| R2834 | T3261 | T3259 | pobj | times,at |
| R2835 | T3262 | T3248 | conj | examined,was |
| R2836 | T3263 | T3266 | punct | (,b |
| R2837 | T3264 | T3265 | compound | Fig.,3a |
| R2838 | T3265 | T3266 | nummod | 3a,b |
| R2839 | T3266 | T3262 | parataxis | b,examined |
| R2840 | T3267 | T3266 | punct | ),b |
| R2841 | T3268 | T3248 | punct | .,was |
| R2842 | T3269 | T3273 | mark | Because,indicated |
| R2843 | T3270 | T3271 | amod | previous,studies |
| R2844 | T3271 | T3273 | nsubj | studies,indicated |
| R2845 | T3272 | T3273 | aux | have,indicated |
| R2846 | T3273 | T3295 | advcl | indicated,examined |
| R2847 | T3274 | T3275 | det | a,role |
| R2848 | T3275 | T3273 | dobj | role,indicated |
| R2849 | T3276 | T3275 | prep | for,role |
| R2850 | T3277 | T3276 | pobj | caspase-1,for |
| R2851 | T3278 | T3277 | prep | in,caspase-1 |
| R2852 | T3279 | T3280 | det | the,activation |
| R2853 | T3280 | T3278 | pobj | activation,in |
| R2854 | T3281 | T3280 | prep | of,activation |
| R2855 | T3282 | T3281 | pobj | NF-κB,of |
| R2856 | T3283 | T3275 | prep | through,role |
| R2857 | T3284 | T3285 | amod | Toll-like,receptor |
| R2858 | T3285 | T3283 | pobj | receptor,through |
| R2859 | T3286 | T3287 | punct | (,TLR |
| R2860 | T3287 | T3285 | appos | TLR,receptor |
| R2861 | T3288 | T3273 | punct | ),indicated |
| R2862 | T3289 | T3273 | advcl | signaling,indicated |
| R2863 | T3290 | T3292 | nmod | [,] |
| R2864 | T3291 | T3292 | nummod | 35,] |
| R2865 | T3292 | T3289 | dobj | ],signaling |
| R2866 | T3293 | T3295 | punct | ",",examined |
| R2867 | T3294 | T3295 | nsubj | we,examined |
| R2868 | T3295 | T3295 | ROOT | examined,examined |
| R2869 | T3296 | T3305 | mark | whether,in |
| R2870 | T3297 | T3298 | compound | chemical,inhibition |
| R2871 | T3298 | T3305 | nsubj | inhibition,in |
| R2872 | T3299 | T3298 | prep | of,inhibition |
| R2873 | T3300 | T3304 | amod | caspase-1,production |
| R2874 | T3301 | T3304 | amod | altered,production |
| R2875 | T3302 | T3304 | nmod | NF-κB-dependent,production |
| R2876 | T3303 | T3304 | compound | IL-6,production |
| R2877 | T3304 | T3299 | pobj | production,of |
| R2878 | T3305 | T3295 | prt | in,examined |
| R2879 | T3306 | T3305 | pobj | response,in |
| R2880 | T3307 | T3306 | prep | to,response |
| R2881 | T3308 | T3309 | compound | P.,aeruginosa |
| R2882 | T3309 | T3307 | pobj | aeruginosa,to |
| R2883 | T3310 | T3295 | punct | .,examined |
| R2884 | T3311 | T3324 | advmod | However,decrease |
| R2885 | T3312 | T3324 | punct | ",",decrease |
| R2886 | T3313 | T3324 | nsubj | treatment,decrease |
| R2887 | T3314 | T3313 | prep | with,treatment |
| R2888 | T3315 | T3317 | det | the,inhibitor |
| R2889 | T3316 | T3317 | amod | caspase-1,inhibitor |
| R2890 | T3317 | T3314 | pobj | inhibitor,with |
| R2891 | T3318 | T3317 | appos | z-YVAD-fmk,inhibitor |
| R2892 | T3319 | T3320 | punct | (,YVAD |
| R2893 | T3320 | T3318 | appos | YVAD,z-YVAD-fmk |
| R2894 | T3321 | T3318 | punct | ),z-YVAD-fmk |
| R2895 | T3322 | T3324 | aux | did,decrease |
| R2896 | T3323 | T3324 | neg | not,decrease |
| R2897 | T3324 | T3324 | ROOT | decrease,decrease |
| R2898 | T3325 | T3326 | compound | IL-6,secretion |
| R2899 | T3326 | T3324 | dobj | secretion,decrease |
| R2900 | T3327 | T3324 | prep | by,decrease |
| R2901 | T3328 | T3330 | nmod | airway,cells |
| R2902 | T3329 | T3330 | amod | epithelial,cells |
| R2903 | T3330 | T3327 | pobj | cells,by |
| R2904 | T3331 | T3324 | punct | (,decrease |
| R2905 | T3332 | T3324 | npadvmod | Fig.,decrease |
| R2906 | T3333 | T3332 | nummod | 3c,Fig. |
| R2907 | T3334 | T3324 | punct | ),decrease |
| R2908 | T3335 | T3324 | punct | .,decrease |
| R11746 | T13246 | T13247 | compound | Airway,cells |
| R11747 | T13247 | T13251 | nsubj | cells,upregulate |
| R11748 | T13248 | T13251 | aux | do,upregulate |
| R11749 | T13249 | T13251 | neg | not,upregulate |
| R11750 | T13250 | T13251 | advmod | strongly,upregulate |
| R11751 | T13251 | T13251 | ROOT | upregulate,upregulate |
| R11752 | T13252 | T13253 | amod | caspase-1,activity |
| R11753 | T13253 | T13251 | dobj | activity,upregulate |
| R11754 | T13254 | T13251 | prep | in,upregulate |
| R11755 | T13255 | T13254 | pobj | response,in |
| R11756 | T13256 | T13255 | prep | to,response |
| R11757 | T13257 | T13258 | amod | inflammasome,stimuli |
| R11758 | T13258 | T13256 | pobj | stimuli,to |
| R11759 | T13259 | T13251 | punct | .,upregulate |
| R11760 | T13260 | T13263 | nummod | S9,cells |
| R11761 | T13261 | T13260 | cc | and,S9 |
| R11762 | T13262 | T13260 | conj | IB3-1,S9 |
| R11763 | T13263 | T13265 | nsubjpass | cells,examined |
| R11764 | T13264 | T13265 | auxpass | were,examined |
| R11765 | T13265 | T13265 | ROOT | examined,examined |
| R11766 | T13266 | T13265 | prep | for,examined |
| R11767 | T13267 | T13268 | amod | caspase-1,activation |
| R11768 | T13268 | T13266 | pobj | activation,for |
| R11769 | T13269 | T13265 | prep | following,examined |
| R11770 | T13270 | T13271 | amod | inflammasome,stimulation |
| R11771 | T13271 | T13269 | pobj | stimulation,following |
| R11772 | T13272 | T13271 | prep | with,stimulation |
| R11773 | T13273 | T13274 | compound | P.,aeruginosa |
| R11774 | T13274 | T13272 | pobj | aeruginosa,with |
| R11775 | T13275 | T13278 | punct | (,10 |
| R11776 | T13276 | T13278 | dep | MOI,10 |
| R11777 | T13277 | T13278 | punct | =,10 |
| R11778 | T13278 | T13274 | appos | 10,aeruginosa |
| R11779 | T13279 | T13274 | punct | ),aeruginosa |
| R11780 | T13280 | T13274 | cc | and,aeruginosa |
| R11781 | T13281 | T13274 | conj | ATP,aeruginosa |
| R11782 | T13282 | T13283 | punct | (,5 |
| R11783 | T13283 | T13284 | nummod | 5,mM |
| R11784 | T13284 | T13281 | appos | mM,ATP |
| R11785 | T13285 | T13281 | punct | ),ATP |
| R11786 | T13286 | T13265 | punct | .,examined |
| R11787 | T13287 | T13289 | nsubjpass | Cells,primed |
| R11788 | T13288 | T13289 | auxpass | were,primed |
| R11789 | T13289 | T13289 | ROOT | primed,primed |
| R11790 | T13290 | T13289 | prep | with,primed |
| R11791 | T13291 | T13290 | pobj | LPS,with |
| R11792 | T13292 | T13289 | prep | for,primed |
| R11793 | T13293 | T13294 | nummod | 5,hours |
| R11794 | T13294 | T13292 | pobj | hours,for |
| R11795 | T13295 | T13296 | advmod | where,appropriate |
| R11796 | T13296 | T13294 | relcl | appropriate,hours |
| R11797 | T13297 | T13289 | punct | .,primed |
| R11798 | T13298 | T13300 | det | A,histogram |
| R11799 | T13299 | T13300 | amod | representative,histogram |
| R11800 | T13300 | T13306 | nsubjpass | histogram,shown |
| R11801 | T13301 | T13300 | prep | of,histogram |
| R11802 | T13302 | T13304 | nmod | %,cells |
| R11803 | T13303 | T13304 | amod | caspase-1-active,cells |
| R11804 | T13304 | T13301 | pobj | cells,of |
| R11805 | T13305 | T13306 | auxpass | is,shown |
| R11806 | T13306 | T13306 | ROOT | shown,shown |
| R11807 | T13307 | T13306 | prep | in,shown |
| R11808 | T13308 | T13309 | punct | (,A |
| R11809 | T13309 | T13307 | pobj | A,in |
| R11810 | T13310 | T13306 | punct | ),shown |
| R11811 | T13311 | T13306 | cc | and,shown |
| R11812 | T13312 | T13314 | det | the,values |
| R11813 | T13313 | T13314 | amod | averaged,values |
| R11814 | T13314 | T13316 | nsubjpass | values,shown |
| R11815 | T13315 | T13316 | auxpass | are,shown |
| R11816 | T13316 | T13306 | conj | shown,shown |
| R11817 | T13317 | T13316 | prep | in,shown |
| R11818 | T13318 | T13319 | punct | (,B |
| R11819 | T13319 | T13317 | pobj | B,in |
| R11820 | T13320 | T13319 | punct | ),B |
| R11821 | T13321 | T13316 | punct | (,shown |
| R11822 | T13322 | T13326 | advmod | n,experiments |
| R11823 | T13323 | T13326 | punct | =,experiments |
| R11824 | T13324 | T13326 | nummod | 3,experiments |
| R11825 | T13325 | T13326 | amod | separate,experiments |
| R11826 | T13326 | T13316 | appos | experiments,shown |
| R11827 | T13327 | T13316 | punct | ),shown |
| R11828 | T13328 | T13316 | punct | .,shown |
| R11829 | T13329 | T13330 | punct | (,C |
| R11830 | T13330 | T13333 | nmod | C,cells |
| R11831 | T13331 | T13330 | punct | ),C |
| R11832 | T13332 | T13333 | amod | IB3-1,cells |
| R11833 | T13333 | T13340 | nsubj | cells,were |
| R11834 | T13334 | T13333 | punct | (,cells |
| R11835 | T13335 | T13338 | nummod | 5,cells/well |
| R11836 | T13336 | T13338 | nummod | ×,cells/well |
| R11837 | T13337 | T13338 | nummod | 104,cells/well |
| R11838 | T13338 | T13333 | appos | cells/well,cells |
| R11839 | T13339 | T13333 | punct | ),cells |
| R11840 | T13340 | T13340 | ROOT | were,were |
| R11841 | T13341 | T13340 | acomp | pre-treated,were |
| R11842 | T13342 | T13341 | prep | for,pre-treated |
| R11843 | T13343 | T13344 | nummod | 1,hour |
| R11844 | T13344 | T13342 | pobj | hour,for |
| R11845 | T13345 | T13344 | prep | with,hour |
| R11846 | T13346 | T13347 | amod | increasing,concentrations |
| R11847 | T13347 | T13345 | pobj | concentrations,with |
| R11848 | T13348 | T13347 | prep | of,concentrations |
| R11849 | T13349 | T13348 | pobj | z-YVAD-fmk,of |
| R11850 | T13350 | T13349 | punct | (,z-YVAD-fmk |
| R11851 | T13351 | T13349 | npadvmod | 10,z-YVAD-fmk |
| R11852 | T13352 | T13353 | nummod | 30,µM |
| R11853 | T13353 | T13349 | appos | µM,z-YVAD-fmk |
| R11854 | T13354 | T13349 | punct | ),z-YVAD-fmk |
| R11855 | T13355 | T13340 | advmod | prior,were |
| R11856 | T13356 | T13355 | prep | to,prior |
| R11857 | T13357 | T13356 | pobj | stimulation,to |
| R11858 | T13358 | T13355 | prep | with,prior |
| R11859 | T13359 | T13360 | compound | P.,aeruginosa |
| R11860 | T13360 | T13358 | pobj | aeruginosa,with |
| R11861 | T13361 | T13362 | punct | (,MOI |
| R11862 | T13362 | T13360 | appos | MOI,aeruginosa |
| R11863 | T13363 | T13364 | punct | =,50 |
| R11864 | T13364 | T13362 | nummod | 50,MOI |
| R11865 | T13365 | T13362 | punct | ),MOI |
| R11866 | T13366 | T13340 | punct | .,were |
| R11867 | T13367 | T13369 | compound | Cell,supernatants |
| R11868 | T13368 | T13369 | compound | culture,supernatants |
| R11869 | T13369 | T13371 | nsubjpass | supernatants,collected |
| R11870 | T13370 | T13371 | auxpass | were,collected |
| R11871 | T13371 | T13371 | ROOT | collected,collected |
| R11872 | T13372 | T13371 | prep | after,collected |
| R11873 | T13373 | T13374 | nummod | 6,hours |
| R11874 | T13374 | T13372 | pobj | hours,after |
| R11875 | T13375 | T13371 | cc | and,collected |
| R11876 | T13376 | T13371 | conj | assayed,collected |
| R11877 | T13377 | T13376 | prep | for,assayed |
| R11878 | T13378 | T13377 | pobj | IL-6,for |
| R11879 | T13379 | T13376 | agent | by,assayed |
| R11880 | T13380 | T13379 | pobj | ELISA,by |
| R11881 | T13381 | T13384 | punct | (,3 |
| R11882 | T13382 | T13384 | advmod | n,3 |
| R11883 | T13383 | T13384 | punct | =,3 |
| R11884 | T13384 | T13384 | ROOT | 3,3 |
| R11885 | T13385 | T13384 | punct | ),3 |
| R11886 | T13386 | T13371 | punct | .,collected |
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3095 | 0-6 | RB | denotes | Airway |
| T3096 | 7-17 | JJ | denotes | epithelial |
| T3097 | 18-23 | NN | denotes | cells |
| T3098 | 24-26 | VB | denotes | do |
| T3099 | 27-30 | RB | denotes | not |
| T3100 | 31-44 | RB | denotes | significantly |
| T3101 | 45-55 | VB | denotes | upregulate |
| T3102 | 56-65 | NN | denotes | caspase-1 |
| T3103 | 66-74 | NN | denotes | activity |
| T3104 | 75-77 | IN | denotes | in |
| T3105 | 78-86 | NN | denotes | response |
| T3106 | 87-89 | TO | denotes | to |
| T3107 | 90-102 | JJ | denotes | inflammasome |
| T3108 | 103-114 | NN | denotes | stimulation |
| T3109 | 115-117 | TO | denotes | To |
| T3110 | 118-125 | VB | denotes | examine |
| T3111 | 126-128 | IN | denotes | if |
| T3112 | 129-141 | JJ | denotes | inflammasome |
| T3113 | 142-152 | NN | denotes | activation |
| T3114 | 153-159 | VB | denotes | occurs |
| T3115 | 160-162 | IN | denotes | in |
| T3116 | 163-168 | DT | denotes | these |
| T3117 | 169-175 | NN | denotes | airway |
| T3118 | 176-181 | NN | denotes | cells |
| T3119 | 181-182 | -COMMA- | denotes | , |
| T3120 | 183-192 | NN | denotes | caspase-1 |
| T3121 | 193-201 | NN | denotes | activity |
| T3122 | 202-205 | VB | denotes | was |
| T3123 | 206-216 | VB | denotes | quantified |
| T3124 | 217-219 | IN | denotes | by |
| T3125 | 220-224 | NN | denotes | flow |
| T3126 | 225-234 | NN | denotes | cytometry |
| T3127 | 236-241 | EX | denotes | There |
| T3128 | 242-245 | VB | denotes | was |
| T3129 | 246-248 | DT | denotes | no |
| T3130 | 249-260 | JJ | denotes | significant |
| T3131 | 261-269 | NN | denotes | increase |
| T3132 | 270-274 | IN | denotes | upon |
| T3133 | 275-286 | NN | denotes | stimulation |
| T3134 | 287-291 | IN | denotes | with |
| T3135 | 292-296 | JJ | denotes | live |
| T3136 | 297-301 | NN | denotes | PAO1 |
| T3137 | 302-304 | CC | denotes | or |
| T3138 | 305-312 | NN | denotes | LPS+ATP |
| T3139 | 313-315 | IN | denotes | at |
| T3140 | 316-319 | DT | denotes | the |
| T3141 | 320-325 | NN | denotes | times |
| T3142 | 326-334 | VB | denotes | examined |
| T3143 | 335-336 | -LRB- | denotes | ( |
| T3144 | 336-340 | NNP | denotes | Fig. |
| T3145 | 341-345 | NN | denotes | 3a–b |
| T3146 | 345-346 | -RRB- | denotes | ) |
| T3147 | 348-355 | IN | denotes | Because |
| T3148 | 356-364 | JJ | denotes | previous |
| T3149 | 365-372 | NN | denotes | studies |
| T3150 | 373-377 | VB | denotes | have |
| T3151 | 378-387 | VB | denotes | indicated |
| T3152 | 388-389 | DT | denotes | a |
| T3153 | 390-394 | NN | denotes | role |
| T3154 | 395-398 | IN | denotes | for |
| T3155 | 399-408 | NN | denotes | caspase-1 |
| T3156 | 409-411 | IN | denotes | in |
| T3157 | 412-415 | DT | denotes | the |
| T3158 | 416-426 | NN | denotes | activation |
| T3159 | 427-429 | IN | denotes | of |
| T3160 | 430-435 | NN | denotes | NF-κB |
| T3161 | 436-443 | IN | denotes | through |
| T3162 | 444-453 | JJ | denotes | Toll-like |
| T3163 | 454-462 | NN | denotes | receptor |
| T3164 | 463-464 | -LRB- | denotes | ( |
| T3165 | 464-467 | NN | denotes | TLR |
| T3166 | 467-468 | -RRB- | denotes | ) |
| T3167 | 469-478 | NN | denotes | signaling |
| T3168 | 479-480 | -LRB- | denotes | [ |
| T3169 | 480-482 | CD | denotes | 35 |
| T3170 | 482-483 | -RRB- | denotes | ] |
| T3171 | 483-484 | -COMMA- | denotes | , |
| T3172 | 485-487 | PRP | denotes | we |
| T3173 | 488-496 | VB | denotes | examined |
| T3174 | 497-504 | IN | denotes | whether |
| T3175 | 505-513 | JJ | denotes | chemical |
| T3176 | 514-524 | NN | denotes | inhibition |
| T3177 | 525-527 | IN | denotes | of |
| T3178 | 528-537 | NN | denotes | caspase-1 |
| T3179 | 538-545 | VB | denotes | altered |
| T3180 | 546-561 | JJ | denotes | NF-κB-dependent |
| T3181 | 562-566 | NN | denotes | IL-6 |
| T3182 | 567-577 | NN | denotes | production |
| T3183 | 578-580 | IN | denotes | in |
| T3184 | 581-589 | NN | denotes | response |
| T3185 | 590-592 | TO | denotes | to |
| T3186 | 593-595 | NNP | denotes | P. |
| T3187 | 596-606 | NN | denotes | aeruginosa |
| T3188 | 608-615 | RB | denotes | However |
| T3189 | 615-616 | -COMMA- | denotes | , |
| T3190 | 617-626 | NN | denotes | treatment |
| T3191 | 627-631 | IN | denotes | with |
| T3192 | 632-635 | DT | denotes | the |
| T3193 | 636-645 | NN | denotes | caspase-1 |
| T3194 | 646-655 | NN | denotes | inhibitor |
| T3195 | 656-666 | NN | denotes | z-YVAD-fmk |
| T3196 | 667-668 | -LRB- | denotes | ( |
| T3197 | 668-672 | NN | denotes | YVAD |
| T3198 | 672-673 | -RRB- | denotes | ) |
| T3199 | 674-677 | VB | denotes | did |
| T3200 | 678-681 | RB | denotes | not |
| T3201 | 682-690 | VB | denotes | decrease |
| T3202 | 691-695 | NN | denotes | IL-6 |
| T3203 | 696-705 | NN | denotes | secretion |
| T3204 | 706-708 | IN | denotes | by |
| T3205 | 709-715 | NN | denotes | airway |
| T3206 | 716-726 | JJ | denotes | epithelial |
| T3207 | 727-732 | NN | denotes | cells |
| T3208 | 733-734 | -LRB- | denotes | ( |
| T3209 | 734-738 | NN | denotes | Fig. |
| T3210 | 739-741 | NN | denotes | 3c |
| T3211 | 741-742 | -RRB- | denotes | ) |
| T13121 | 788-794 | NN | denotes | Airway |
| T13122 | 795-800 | NN | denotes | cells |
| T13123 | 801-803 | VB | denotes | do |
| T13124 | 804-807 | RB | denotes | not |
| T13125 | 808-816 | RB | denotes | strongly |
| T13126 | 817-827 | VB | denotes | upregulate |
| T13127 | 828-837 | NN | denotes | caspase-1 |
| T13128 | 838-846 | NN | denotes | activity |
| T13129 | 847-849 | IN | denotes | in |
| T13130 | 850-858 | NN | denotes | response |
| T13131 | 859-861 | TO | denotes | to |
| T13132 | 862-874 | JJ | denotes | inflammasome |
| T13133 | 875-882 | NN | denotes | stimuli |
| T13134 | 884-886 | NN | denotes | S9 |
| T13135 | 887-890 | CC | denotes | and |
| T13136 | 891-896 | NN | denotes | IB3-1 |
| T13137 | 897-902 | NN | denotes | cells |
| T13138 | 903-907 | VB | denotes | were |
| T13139 | 908-916 | VB | denotes | examined |
| T13140 | 917-920 | IN | denotes | for |
| T13141 | 921-930 | NN | denotes | caspase-1 |
| T13142 | 931-941 | NN | denotes | activation |
| T13143 | 942-951 | VB | denotes | following |
| T13144 | 952-964 | JJ | denotes | inflammasome |
| T13145 | 965-976 | NN | denotes | stimulation |
| T13146 | 977-981 | IN | denotes | with |
| T13147 | 982-984 | NNP | denotes | P. |
| T13148 | 985-995 | NN | denotes | aeruginosa |
| T13149 | 996-997 | -LRB- | denotes | ( |
| T13150 | 997-1005 | NN | denotes | MOI = 10 |
| T13151 | 1005-1006 | -RRB- | denotes | ) |
| T13152 | 1007-1010 | CC | denotes | and |
| T13153 | 1011-1014 | NN | denotes | ATP |
| T13154 | 1015-1016 | -LRB- | denotes | ( |
| T13155 | 1016-1017 | CD | denotes | 5 |
| T13156 | 1018-1020 | NN | denotes | mM |
| T13157 | 1020-1021 | -RRB- | denotes | ) |
| T13158 | 1023-1028 | NN | denotes | Cells |
| T13159 | 1029-1033 | VB | denotes | were |
| T13160 | 1034-1040 | VB | denotes | primed |
| T13161 | 1041-1045 | IN | denotes | with |
| T13162 | 1046-1049 | NN | denotes | LPS |
| T13163 | 1050-1053 | IN | denotes | for |
| T13164 | 1054-1055 | CD | denotes | 5 |
| T13165 | 1056-1061 | NN | denotes | hours |
| T13166 | 1062-1067 | WRB | denotes | where |
| T13167 | 1068-1079 | JJ | denotes | appropriate |
| T13168 | 1081-1082 | DT | denotes | A |
| T13169 | 1083-1097 | JJ | denotes | representative |
| T13170 | 1098-1107 | NN | denotes | histogram |
| T13171 | 1108-1110 | IN | denotes | of |
| T13172 | 1111-1112 | NN | denotes | % |
| T13173 | 1113-1129 | JJ | denotes | caspase-1-active |
| T13174 | 1130-1135 | NN | denotes | cells |
| T13175 | 1136-1138 | VB | denotes | is |
| T13176 | 1139-1144 | VB | denotes | shown |
| T13177 | 1145-1147 | IN | denotes | in |
| T13178 | 1148-1149 | -LRB- | denotes | ( |
| T13179 | 1149-1150 | NN | denotes | A |
| T13180 | 1150-1151 | -RRB- | denotes | ) |
| T13181 | 1152-1155 | CC | denotes | and |
| T13182 | 1156-1159 | DT | denotes | the |
| T13183 | 1160-1168 | JJ | denotes | averaged |
| T13184 | 1169-1175 | NN | denotes | values |
| T13185 | 1176-1179 | VB | denotes | are |
| T13186 | 1180-1185 | VB | denotes | shown |
| T13187 | 1186-1188 | IN | denotes | in |
| T13188 | 1189-1190 | -LRB- | denotes | ( |
| T13189 | 1190-1191 | NN | denotes | B |
| T13190 | 1191-1192 | -RRB- | denotes | ) |
| T13191 | 1193-1194 | -LRB- | denotes | ( |
| T13192 | 1194-1199 | NN | denotes | n = 3 |
| T13193 | 1200-1208 | JJ | denotes | separate |
| T13194 | 1209-1220 | NN | denotes | experiments |
| T13195 | 1220-1221 | -RRB- | denotes | ) |
| T13196 | 1221-1222 | -LRB- | denotes | . |
| T13197 | 1223-1224 | NN | denotes | ( |
| T13198 | 1224-1225 | -RRB- | denotes | C |
| T13199 | 1225-1230 | NN | denotes | ) IB3 |
| T13200 | 1230-1235 | NN | denotes | -1 ce |
| T13201 | 1235-1236 | -LRB- | denotes | l |
| T13202 | 1236-1241 | CD | denotes | ls (5 |
| T13203 | 1241-1251 | NN | denotes | ×104 cells |
| T13204 | 1251-1252 | -RRB- | denotes | / |
| T13205 | 1252-1256 | VB | denotes | well |
| T13206 | 1256-1267 | VB | denotes | ) were pre- |
| T13207 | 1267-1270 | IN | denotes | tre |
| T13208 | 1270-1271 | CD | denotes | a |
| T13209 | 1271-1275 | NN | denotes | ted |
| T13210 | 1275-1279 | IN | denotes | for |
| T13211 | 1279-1289 | VB | denotes | 1 hour wit |
| T13212 | 1289-1303 | NN | denotes | h increasing c |
| T13213 | 1303-1305 | IN | denotes | on |
| T13214 | 1305-1315 | NN | denotes | centration |
| T13215 | 1315-1316 | -LRB- | denotes | s |
| T13216 | 1317-1322 | CD | denotes | of z- |
| T13217 | 1322-1324 | NN | denotes | YV |
| T13218 | 1324-1325 | -RRB- | denotes | A |
| T13219 | 1325-1330 | JJ | denotes | D-fmk |
| T13220 | 1331-1333 | TO | denotes | (1 |
| T13221 | 1333-1344 | NN | denotes | 0–30 µM) pr |
| T13222 | 1344-1348 | IN | denotes | ior |
| T13223 | 1348-1350 | NNP | denotes | to |
| T13224 | 1351-1361 | NN | denotes | stimulatio |
| T13225 | 1361-1362 | -LRB- | denotes | n |
| T13226 | 1363-1371 | NN | denotes | with P. |
| T13227 | 1371-1372 | -RRB- | denotes | a |
| T13228 | 1394-1398 | NN | denotes | Cell |
| T13229 | 1399-1406 | NN | denotes | culture |
| T13230 | 1407-1419 | NN | denotes | supernatants |
| T13231 | 1420-1424 | VB | denotes | were |
| T13232 | 1425-1434 | VB | denotes | collected |
| T13233 | 1435-1440 | IN | denotes | after |
| T13234 | 1441-1442 | CD | denotes | 6 |
| T13235 | 1443-1448 | NN | denotes | hours |
| T13236 | 1449-1452 | CC | denotes | and |
| T13237 | 1453-1460 | VB | denotes | assayed |
| T13238 | 1461-1464 | IN | denotes | for |
| T13239 | 1465-1469 | NN | denotes | IL-6 |
| T13240 | 1470-1472 | IN | denotes | by |
| T13241 | 1473-1478 | NN | denotes | ELISA |
| T13242 | 1479-1480 | -LRB- | denotes | ( |
| T13243 | 1480-1485 | NN | denotes | n = 3 |
| T13244 | 1485-1486 | -RRB- | denotes | ) |
| R2671 | T3097 | T3096 | arg1Of | cells,epithelial |
| R2672 | T3097 | T3098 | arg1Of | cells,do |
| R2673 | T3097 | T3101 | arg1Of | cells,upregulate |
| R2674 | T3101 | T3095 | arg1Of | upregulate,Airway |
| R2675 | T3101 | T3098 | arg2Of | upregulate,do |
| R2676 | T3101 | T3099 | arg1Of | upregulate,not |
| R2677 | T3101 | T3100 | arg1Of | upregulate,significantly |
| R2678 | T3101 | T3104 | arg1Of | upregulate,in |
| R2679 | T3103 | T3101 | arg2Of | activity,upregulate |
| R2680 | T3103 | T3102 | arg1Of | activity,caspase-1 |
| R2681 | T3105 | T3104 | arg2Of | response,in |
| R2682 | T3105 | T3106 | arg1Of | response,to |
| R2683 | T3108 | T3106 | arg2Of | stimulation,to |
| R2684 | T3108 | T3107 | arg1Of | stimulation,inflammasome |
| R2685 | T3110 | T3109 | arg1Of | examine,To |
| R2686 | T3113 | T3112 | arg1Of | activation,inflammasome |
| R2687 | T3113 | T3114 | arg1Of | activation,occurs |
| R2688 | T3114 | T3110 | arg2Of | occurs,examine |
| R2689 | T3114 | T3111 | arg1Of | occurs,if |
| R2690 | T3114 | T3115 | arg1Of | occurs,in |
| R2691 | T3118 | T3115 | arg2Of | cells,in |
| R2692 | T3118 | T3116 | arg1Of | cells,these |
| R2693 | T3118 | T3117 | arg1Of | cells,airway |
| R2694 | T3121 | T3120 | arg1Of | activity,caspase-1 |
| R2695 | T3121 | T3122 | arg1Of | activity,was |
| R2696 | T3121 | T3123 | arg2Of | activity,quantified |
| R2697 | T3123 | T3109 | modOf | quantified,To |
| R2698 | T3123 | T3119 | arg1Of | quantified,"," |
| R2699 | T3123 | T3122 | arg2Of | quantified,was |
| R2700 | T3126 | T3123 | arg1Of | cytometry,quantified |
| R2701 | T3126 | T3124 | arg2Of | cytometry,by |
| R2702 | T3126 | T3125 | arg1Of | cytometry,flow |
| R2703 | T3127 | T3128 | arg1Of | There,was |
| R2704 | T3128 | T3132 | arg1Of | was,upon |
| R2705 | T3131 | T3128 | arg2Of | increase,was |
| R2706 | T3131 | T3129 | arg1Of | increase,no |
| R2707 | T3131 | T3130 | arg1Of | increase,significant |
| R2708 | T3133 | T3132 | arg2Of | stimulation,upon |
| R2709 | T3133 | T3134 | arg1Of | stimulation,with |
| R2710 | T3133 | T3139 | arg1Of | stimulation,at |
| R2711 | T3136 | T3137 | arg1Of | PAO1,or |
| R2712 | T3137 | T3134 | arg2Of | or,with |
| R2713 | T3137 | T3135 | arg1Of | or,live |
| R2714 | T3138 | T3137 | arg2Of | LPS+ATP,or |
| R2715 | T3141 | T3139 | arg2Of | times,at |
| R2716 | T3141 | T3140 | arg1Of | times,the |
| R2717 | T3141 | T3142 | arg2Of | times,examined |
| R2718 | T3142 | T3143 | arg1Of | examined,( |
| R2719 | T3145 | T3143 | arg2Of | 3a–b,( |
| R2720 | T3145 | T3144 | arg1Of | 3a–b,Fig. |
| R2721 | T3146 | T3143 | arg3Of | ),( |
| R2722 | T3149 | T3148 | arg1Of | studies,previous |
| R2723 | T3149 | T3150 | arg1Of | studies,have |
| R2724 | T3149 | T3151 | arg1Of | studies,indicated |
| R2725 | T3151 | T3147 | arg2Of | indicated,Because |
| R2726 | T3151 | T3150 | arg2Of | indicated,have |
| R2727 | T3153 | T3151 | arg2Of | role,indicated |
| R2728 | T3153 | T3152 | arg1Of | role,a |
| R2729 | T3153 | T3154 | arg1Of | role,for |
| R2730 | T3153 | T3156 | arg1Of | role,in |
| R2731 | T3155 | T3154 | arg2Of | caspase-1,for |
| R2732 | T3158 | T3156 | arg2Of | activation,in |
| R2733 | T3158 | T3157 | arg1Of | activation,the |
| R2734 | T3158 | T3159 | arg1Of | activation,of |
| R2735 | T3158 | T3161 | arg1Of | activation,through |
| R2736 | T3160 | T3159 | arg2Of | NF-κB,of |
| R2737 | T3163 | T3162 | arg1Of | receptor,Toll-like |
| R2738 | T3163 | T3164 | arg1Of | receptor,( |
| R2739 | T3165 | T3164 | arg2Of | TLR,( |
| R2740 | T3166 | T3164 | arg3Of | ),( |
| R2741 | T3167 | T3161 | arg2Of | signaling,through |
| R2742 | T3167 | T3163 | arg1Of | signaling,receptor |
| R2743 | T3167 | T3168 | arg1Of | signaling,[ |
| R2744 | T3169 | T3168 | arg2Of | 35,[ |
| R2745 | T3170 | T3168 | arg3Of | ],[ |
| R2746 | T3172 | T3173 | arg1Of | we,examined |
| R2747 | T3173 | T3147 | arg1Of | examined,Because |
| R2748 | T3173 | T3171 | arg1Of | examined,"," |
| R2749 | T3176 | T3175 | arg1Of | inhibition,chemical |
| R2750 | T3176 | T3177 | arg1Of | inhibition,of |
| R2751 | T3176 | T3179 | arg1Of | inhibition,altered |
| R2752 | T3178 | T3177 | arg2Of | caspase-1,of |
| R2753 | T3179 | T3173 | arg2Of | altered,examined |
| R2754 | T3179 | T3174 | arg1Of | altered,whether |
| R2755 | T3179 | T3183 | arg1Of | altered,in |
| R2756 | T3182 | T3179 | arg2Of | production,altered |
| R2757 | T3182 | T3180 | arg1Of | production,NF-κB-dependent |
| R2758 | T3182 | T3181 | arg1Of | production,IL-6 |
| R2759 | T3184 | T3183 | arg2Of | response,in |
| R2760 | T3184 | T3185 | arg1Of | response,to |
| R2761 | T3187 | T3185 | arg2Of | aeruginosa,to |
| R2762 | T3187 | T3186 | arg1Of | aeruginosa,P. |
| R2763 | T3190 | T3191 | arg1Of | treatment,with |
| R2764 | T3190 | T3199 | arg1Of | treatment,did |
| R2765 | T3190 | T3201 | arg1Of | treatment,decrease |
| R2766 | T3195 | T3191 | arg2Of | z-YVAD-fmk,with |
| R2767 | T3195 | T3192 | arg1Of | z-YVAD-fmk,the |
| R2768 | T3195 | T3193 | arg1Of | z-YVAD-fmk,caspase-1 |
| R2769 | T3195 | T3194 | arg1Of | z-YVAD-fmk,inhibitor |
| R2770 | T3195 | T3196 | arg1Of | z-YVAD-fmk,( |
| R2771 | T3197 | T3196 | arg2Of | YVAD,( |
| R2772 | T3198 | T3196 | arg3Of | ),( |
| R2773 | T3201 | T3188 | arg1Of | decrease,However |
| R2774 | T3201 | T3189 | arg1Of | decrease,"," |
| R2775 | T3201 | T3199 | arg2Of | decrease,did |
| R2776 | T3201 | T3200 | arg1Of | decrease,not |
| R2777 | T3201 | T3204 | arg1Of | decrease,by |
| R2778 | T3203 | T3201 | arg2Of | secretion,decrease |
| R2779 | T3203 | T3202 | arg1Of | secretion,IL-6 |
| R2780 | T3207 | T3204 | arg2Of | cells,by |
| R2781 | T3207 | T3205 | arg1Of | cells,airway |
| R2782 | T3207 | T3206 | arg1Of | cells,epithelial |
| R2783 | T3207 | T3208 | arg1Of | cells,( |
| R2784 | T3210 | T3208 | arg2Of | 3c,( |
| R2785 | T3210 | T3209 | arg1Of | 3c,Fig. |
| R2786 | T3211 | T3208 | arg3Of | ),( |
| R11618 | T13122 | T13121 | arg1Of | cells,Airway |
| R11619 | T13122 | T13123 | arg1Of | cells,do |
| R11620 | T13122 | T13126 | arg1Of | cells,upregulate |
| R11621 | T13126 | T13123 | arg2Of | upregulate,do |
| R11622 | T13126 | T13124 | arg1Of | upregulate,not |
| R11623 | T13126 | T13125 | arg1Of | upregulate,strongly |
| R11624 | T13126 | T13129 | arg1Of | upregulate,in |
| R11625 | T13128 | T13126 | arg2Of | activity,upregulate |
| R11626 | T13128 | T13127 | arg1Of | activity,caspase-1 |
| R11627 | T13130 | T13129 | arg2Of | response,in |
| R11628 | T13130 | T13131 | arg1Of | response,to |
| R11629 | T13133 | T13131 | arg2Of | stimuli,to |
| R11630 | T13133 | T13132 | arg1Of | stimuli,inflammasome |
| R11631 | T13134 | T13135 | arg1Of | S9,and |
| R11632 | T13136 | T13135 | arg2Of | IB3-1,and |
| R11633 | T13137 | T13134 | arg1Of | cells,S9 |
| R11634 | T13137 | T13136 | arg1Of | cells,IB3-1 |
| R11635 | T13137 | T13138 | arg1Of | cells,were |
| R11636 | T13137 | T13139 | arg2Of | cells,examined |
| R11637 | T13139 | T13138 | arg2Of | examined,were |
| R11638 | T13139 | T13140 | arg1Of | examined,for |
| R11639 | T13139 | T13143 | arg1Of | examined,following |
| R11640 | T13142 | T13140 | arg2Of | activation,for |
| R11641 | T13142 | T13141 | arg1Of | activation,caspase-1 |
| R11642 | T13145 | T13143 | arg2Of | stimulation,following |
| R11643 | T13145 | T13144 | arg1Of | stimulation,inflammasome |
| R11644 | T13145 | T13146 | arg1Of | stimulation,with |
| R11645 | T13148 | T13147 | arg1Of | aeruginosa,P. |
| R11646 | T13148 | T13149 | arg1Of | aeruginosa,( |
| R11647 | T13148 | T13152 | arg1Of | aeruginosa,and |
| R11648 | T13150 | T13149 | arg2Of | MOI = 10,( |
| R11649 | T13151 | T13149 | arg3Of | ),( |
| R11650 | T13152 | T13146 | arg2Of | and,with |
| R11651 | T13153 | T13152 | arg2Of | ATP,and |
| R11652 | T13153 | T13154 | arg1Of | ATP,( |
| R11653 | T13156 | T13154 | arg2Of | mM,( |
| R11654 | T13156 | T13155 | arg1Of | mM,5 |
| R11655 | T13157 | T13154 | arg3Of | ),( |
| R11656 | T13158 | T13159 | arg1Of | Cells,were |
| R11657 | T13158 | T13160 | arg2Of | Cells,primed |
| R11658 | T13160 | T13159 | arg2Of | primed,were |
| R11659 | T13160 | T13161 | arg1Of | primed,with |
| R11660 | T13160 | T13163 | arg1Of | primed,for |
| R11737 | T13236 | T13231 | arg2Of | and,were |
| R11661 | T13160 | T13166 | arg1Of | primed,where |
| R11662 | T13162 | T13161 | arg2Of | LPS,with |
| R11663 | T13165 | T13163 | arg2Of | hours,for |
| R11664 | T13165 | T13164 | arg1Of | hours,5 |
| R11665 | T13167 | T13166 | arg2Of | appropriate,where |
| R11666 | T13170 | T13168 | arg1Of | histogram,A |
| R11667 | T13170 | T13169 | arg1Of | histogram,representative |
| R11668 | T13170 | T13171 | arg1Of | histogram,of |
| R11669 | T13170 | T13175 | arg1Of | histogram,is |
| R11670 | T13170 | T13176 | arg2Of | histogram,shown |
| R11671 | T13174 | T13171 | arg2Of | cells,of |
| R11672 | T13174 | T13172 | arg1Of | cells,% |
| R11673 | T13174 | T13173 | arg1Of | cells,caspase-1-active |
| R11674 | T13176 | T13175 | arg2Of | shown,is |
| R11675 | T13176 | T13177 | arg1Of | shown,in |
| R11676 | T13176 | T13181 | arg1Of | shown,and |
| R11677 | T13179 | T13177 | arg2Of | A,in |
| R11678 | T13179 | T13178 | arg2Of | A,( |
| R11679 | T13180 | T13178 | arg3Of | ),( |
| R11680 | T13184 | T13182 | arg1Of | values,the |
| R11681 | T13184 | T13183 | arg1Of | values,averaged |
| R11682 | T13184 | T13185 | arg1Of | values,are |
| R11683 | T13184 | T13186 | arg2Of | values,shown |
| R11684 | T13186 | T13181 | arg2Of | shown,and |
| R11685 | T13186 | T13185 | arg2Of | shown,are |
| R11686 | T13186 | T13187 | arg1Of | shown,in |
| R11687 | T13189 | T13187 | arg2Of | B,in |
| R11688 | T13189 | T13188 | arg2Of | B,( |
| R11689 | T13189 | T13191 | arg1Of | B,( |
| R11690 | T13189 | T13205 | modOf | B,well |
| R11691 | T13189 | T13219 | arg1Of | B,D-fmk |
| R11692 | T13190 | T13188 | arg3Of | ),( |
| R11693 | T13194 | T13191 | arg2Of | experiments,( |
| R11694 | T13194 | T13192 | arg1Of | experiments,n = 3 |
| R11695 | T13194 | T13193 | arg1Of | experiments,separate |
| R11696 | T13195 | T13191 | arg3Of | ),( |
| R11697 | T13197 | T13196 | arg2Of | (,. |
| R11698 | T13198 | T13196 | arg3Of | C,. |
| R11699 | T13200 | T13196 | arg1Of | -1 ce,. |
| R11700 | T13200 | T13199 | arg1Of | -1 ce,) IB3 |
| R11701 | T13200 | T13201 | arg1Of | -1 ce,l |
| R11702 | T13200 | T13205 | arg1Of | -1 ce,well |
| R11703 | T13200 | T13206 | arg2Of | -1 ce,) were pre- |
| R11704 | T13203 | T13201 | arg2Of | ×104 cells,l |
| R11705 | T13203 | T13202 | arg1Of | ×104 cells,ls (5 |
| R11706 | T13204 | T13201 | arg3Of | /,l |
| R11707 | T13206 | T13205 | arg2Of | ) were pre-,well |
| R11708 | T13206 | T13207 | arg1Of | ) were pre-,tre |
| R11709 | T13209 | T13207 | arg2Of | ted ,tre |
| R11710 | T13209 | T13208 | arg1Of | ted ,a |
| R11711 | T13209 | T13210 | arg1Of | ted ,for |
| R11712 | T13212 | T13210 | arg2Of | h increasing c,for |
| R11713 | T13212 | T13211 | arg1Of | h increasing c,1 hour wit |
| R11714 | T13212 | T13213 | arg1Of | h increasing c,on |
| R11715 | T13214 | T13213 | arg2Of | centration,on |
| R11716 | T13214 | T13215 | arg1Of | centration,s |
| R11717 | T13217 | T13215 | arg2Of | YV,s |
| R11718 | T13217 | T13216 | arg1Of | YV,of z- |
| R11719 | T13218 | T13215 | arg3Of | A,s |
| R11720 | T13219 | T13220 | arg1Of | D-fmk,(1 |
| R11721 | T13221 | T13220 | arg2Of | 0–30 µM) pr,(1 |
| R11722 | T13221 | T13222 | arg1Of | 0–30 µM) pr,ior |
| R11723 | T13224 | T13222 | arg2Of | stimulatio,ior |
| R11724 | T13224 | T13223 | arg1Of | stimulatio,to |
| R11725 | T13224 | T13225 | arg1Of | stimulatio,n |
| R11726 | T13226 | T13225 | arg2Of | with P. ,n |
| R11727 | T13227 | T13225 | arg3Of | a,n |
| R11728 | T13230 | T13228 | arg1Of | supernatants,Cell |
| R11729 | T13230 | T13229 | arg1Of | supernatants,culture |
| R11730 | T13230 | T13231 | arg1Of | supernatants,were |
| R11731 | T13230 | T13232 | arg2Of | supernatants,collected |
| R11732 | T13230 | T13237 | arg2Of | supernatants,assayed |
| R11733 | T13232 | T13233 | arg1Of | collected,after |
| R11734 | T13232 | T13236 | arg1Of | collected,and |
| R11735 | T13235 | T13233 | arg2Of | hours,after |
| R11736 | T13235 | T13234 | arg1Of | hours,6 |
| R11738 | T13237 | T13236 | arg2Of | assayed,and |
| R11739 | T13237 | T13238 | arg1Of | assayed,for |
| R11740 | T13239 | T13238 | arg2Of | IL-6,for |
| R11741 | T13241 | T13237 | arg1Of | ELISA,assayed |
| R11742 | T13241 | T13240 | arg2Of | ELISA,by |
| R11743 | T13241 | T13242 | arg1Of | ELISA,( |
| R11744 | T13243 | T13242 | arg2Of | n = 3,( |
| R11745 | T13244 | T13242 | arg3Of | ),( |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3090 | 0-114 | Sentence | denotes | Airway epithelial cells do not significantly upregulate caspase-1 activity in response to inflammasome stimulation |
| T3091 | 115-235 | Sentence | denotes | To examine if inflammasome activation occurs in these airway cells, caspase-1 activity was quantified by flow cytometry. |
| T3092 | 236-347 | Sentence | denotes | There was no significant increase upon stimulation with live PAO1 or LPS+ATP at the times examined (Fig. 3a–b). |
| T3093 | 348-607 | Sentence | denotes | Because previous studies have indicated a role for caspase-1 in the activation of NF-κB through Toll-like receptor (TLR) signaling [35], we examined whether chemical inhibition of caspase-1 altered NF-κB-dependent IL-6 production in response to P. aeruginosa. |
| T3094 | 608-743 | Sentence | denotes | However, treatment with the caspase-1 inhibitor z-YVAD-fmk (YVAD) did not decrease IL-6 secretion by airway epithelial cells (Fig. 3c). |
| T13116 | 788-883 | Sentence | denotes | Airway cells do not strongly upregulate caspase-1 activity in response to inflammasome stimuli. |
| T13117 | 884-1022 | Sentence | denotes | S9 and IB3-1 cells were examined for caspase-1 activation following inflammasome stimulation with P. aeruginosa (MOI = 10) and ATP (5 mM). |
| T13118 | 1023-1080 | Sentence | denotes | Cells were primed with LPS for 5 hours where appropriate. |
| T13119 | 1081-1393 | Sentence | denotes | A representative histogram of % caspase-1-active cells is shown in (A) and the averaged values are shown in (B) (n = 3 separate experiments). (C) IB3-1 cells (5×104 cells/well) were pre-treated for 1 hour with increasing concentrations of z-YVAD-fmk (10–30 µM) prior to stimulation with P. aeruginosa (MOI = 50). |
| T13120 | 1394-1487 | Sentence | denotes | Cell culture supernatants were collected after 6 hours and assayed for IL-6 by ELISA (n = 3). |
| T59 | 0-114 | Sentence | denotes | Airway epithelial cells do not significantly upregulate caspase-1 activity in response to inflammasome stimulation |
| T60 | 115-235 | Sentence | denotes | To examine if inflammasome activation occurs in these airway cells, caspase-1 activity was quantified by flow cytometry. |
| T61 | 236-347 | Sentence | denotes | There was no significant increase upon stimulation with live PAO1 or LPS+ATP at the times examined (Fig. 3a–b). |
| T62 | 348-607 | Sentence | denotes | Because previous studies have indicated a role for caspase-1 in the activation of NF-κB through Toll-like receptor (TLR) signaling [35], we examined whether chemical inhibition of caspase-1 altered NF-κB-dependent IL-6 production in response to P. aeruginosa. |
| T63 | 608-743 | Sentence | denotes | However, treatment with the caspase-1 inhibitor z-YVAD-fmk (YVAD) did not decrease IL-6 secretion by airway epithelial cells (Fig. 3c). |
| T64 | 744-883 | Sentence | denotes | 10.1371/journal.pone.0037689.g003 Figure 3 Airway cells do not strongly upregulate caspase-1 activity in response to inflammasome stimuli. |
| T65 | 884-1022 | Sentence | denotes | S9 and IB3-1 cells were examined for caspase-1 activation following inflammasome stimulation with P. aeruginosa (MOI = 10) and ATP (5 mM). |
| T66 | 1023-1080 | Sentence | denotes | Cells were primed with LPS for 5 hours where appropriate. |
| T67 | 1081-1393 | Sentence | denotes | A representative histogram of % caspase-1-active cells is shown in (A) and the averaged values are shown in (B) (n = 3 separate experiments). (C) IB3-1 cells (5×104 cells/well) were pre-treated for 1 hour with increasing concentrations of z-YVAD-fmk (10–30 µM) prior to stimulation with P. aeruginosa (MOI = 50). |
| T68 | 1394-1487 | Sentence | denotes | Cell culture supernatants were collected after 6 hours and assayed for IL-6 by ELISA (n = 3). |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 22649552-17360653-88306708 | 480-482 | 17360653 | denotes | 35 |
| T60341 | 480-482 | 17360653 | denotes | 35 |