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PMC:3359311 / 28196-29480 JSONTXT

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bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T10860 904-917 Protein denotes complete RPMI

GO-CC

Id Subject Object Predicate Lexical cue
T10858 995-999 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T10859 1162-1167 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T10856 508-530 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T10857 603-606 http://purl.obolibrary.org/obo/GO_0007568 denotes age

UBERON-AE

Id Subject Object Predicate Lexical cue
T10409 105-110 http://purl.obolibrary.org/obo/UBERON_0001089 denotes sweat
T10410 248-253 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T10411 662-667 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T10412 700-705 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tubes
T10413 1266-1271 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T10630 0-2 NNP denotes CF
T10631 3-6 CC denotes and
T10632 7-14 VB denotes control
T10633 15-22 JJ denotes subject
T10634 23-28 NNP denotes PBMCs
T10635 29-32 DT denotes The
T10636 33-42 NN denotes diagnosis
T10637 43-45 IN denotes of
T10638 46-48 NNP denotes CF
T10639 49-52 VBD denotes was
T10640 53-64 VBN denotes established
T10641 65-67 IN denotes by
T10642 68-75 JJ denotes typical
T10643 76-84 JJ denotes clinical
T10644 85-93 NNS denotes features
T10645 93-94 , denotes ,
T10646 95-104 VBD denotes increased
T10647 105-110 NN denotes sweat
T10648 111-119 NN denotes chloride
T10649 120-134 NNS denotes concentrations
T10650 135-136 -LRB- denotes (
T10651 136-137 CD denotes >
T10652 137-139 CD denotes 60
T10653 140-146 NN denotes mmol/l
T10654 146-147 -RRB- denotes )
T10655 147-148 , denotes ,
T10656 149-152 CC denotes and
T10657 153-162 NN denotes detection
T10658 163-165 IN denotes of
T10659 166-177 VBG denotes CF-inducing
T10660 178-187 NNS denotes mutations
T10661 187-188 . denotes .
T10662 189-192 DT denotes All
T10663 193-201 NNS denotes patients
T10664 202-206 IN denotes with
T10665 207-209 NNP denotes CF
T10666 210-214 VBD denotes were
T10667 215-225 RB denotes clinically
T10668 226-232 JJ denotes stable
T10669 233-235 IN denotes at
T10670 236-239 DT denotes the
T10671 240-244 NN denotes time
T10672 245-247 IN denotes of
T10673 248-253 NN denotes blood
T10674 254-262 NN denotes donation
T10675 262-263 , denotes ,
T10676 264-267 CC denotes and
T10677 268-270 PRP denotes we
T10678 271-279 VBD denotes excluded
T10679 280-283 DT denotes any
T10680 284-292 NNS denotes subjects
T10681 293-296 WP denotes who
T10682 297-301 VBD denotes were
T10683 302-311 VBG denotes receiving
T10684 312-320 JJ denotes systemic
T10685 321-336 NNS denotes corticosteroids
T10686 337-340 JJ denotes due
T10687 341-343 TO denotes to
T10688 344-353 JJ denotes potential
T10689 354-370 JJ denotes immunomodulatory
T10690 371-379 NN denotes activity
T10691 379-380 . denotes .
T10692 381-388 NNP denotes Control
T10693 389-396 NNS denotes samples
T10694 397-401 VBD denotes were
T10695 402-410 VBN denotes provided
T10696 411-413 IN denotes by
T10697 414-421 JJ denotes healthy
T10698 422-427 NN denotes adult
T10699 428-438 NNS denotes volunteers
T10700 438-439 . denotes .
T10701 440-442 IN denotes In
T10702 443-453 RB denotes previously
T10703 454-463 VBN denotes published
T10704 464-468 NN denotes work
T10705 469-471 PRP denotes we
T10706 472-476 VBP denotes have
T10707 477-489 VBN denotes demonstrated
T10708 490-494 IN denotes that
T10709 495-507 JJ denotes TLR-mediated
T10710 508-520 JJ denotes inflammatory
T10711 521-530 NNS denotes responses
T10712 531-534 VBP denotes are
T10713 535-541 JJ denotes stable
T10714 542-544 IN denotes in
T10715 545-551 NNS denotes humans
T10716 552-556 IN denotes from
T10717 557-562 NN denotes birth
T10718 563-565 TO denotes to
T10719 566-568 CD denotes 60
T10720 569-574 NNS denotes years
T10721 575-578 JJ denotes old
T10722 579-580 NNP denotes [
T10723 580-582 CD denotes 63
T10724 582-583 NNP denotes ]
T10725 583-584 , denotes ,
T10726 585-594 RB denotes therefore
T10727 595-598 VBD denotes did
T10728 599-602 RB denotes not
T10729 603-612 JJ denotes age-match
T10730 613-616 DT denotes the
T10731 617-619 NNP denotes CF
T10732 620-628 NNS denotes patients
T10733 629-632 CC denotes and
T10734 633-640 NN denotes control
T10735 641-649 NNS denotes subjects
T10736 649-650 . denotes .
T10737 651-661 JJ denotes Peripheral
T10738 662-667 NN denotes blood
T10739 668-671 VBD denotes was
T10740 672-681 VBN denotes collected
T10741 682-684 IN denotes in
T10742 685-691 NN denotes sodium
T10743 692-699 NN denotes heparin
T10744 700-705 NNS denotes tubes
T10745 706-707 -LRB- denotes (
T10746 707-709 NNP denotes BD
T10747 710-721 NNPS denotes Biosciences
T10748 721-722 -RRB- denotes )
T10749 723-726 CC denotes and
T10750 727-732 NNS denotes PBMCs
T10751 733-737 VBD denotes were
T10752 738-746 VBN denotes isolated
T10753 747-752 VBG denotes using
T10754 753-760 NN denotes density
T10755 761-769 NN denotes gradient
T10756 770-784 NN denotes centrifugation
T10757 785-787 IN denotes on
T10758 788-800 NNP denotes Ficoll-Paque
T10759 800-801 NNP denotes ™
T10760 802-806 NNP denotes Plus
T10761 807-808 -LRB- denotes (
T10762 808-810 NNP denotes GE
T10763 811-821 NNP denotes Healthcare
T10764 821-822 -RRB- denotes )
T10765 822-823 . denotes .
T10766 824-827 DT denotes The
T10767 828-833 NN denotes layer
T10768 834-844 VBG denotes containing
T10769 845-850 NNP denotes PBMCs
T10770 851-854 VBD denotes was
T10771 855-863 VBN denotes isolated
T10772 863-864 , denotes ,
T10773 865-871 VBN denotes washed
T10774 872-877 RB denotes twice
T10775 878-880 IN denotes in
T10776 881-884 NNP denotes PBS
T10777 885-888 CC denotes and
T10778 889-900 VBD denotes resuspended
T10779 901-903 IN denotes in
T10780 904-912 JJ denotes complete
T10781 913-917 NNP denotes RPMI
T10782 917-918 . denotes .
T10783 919-924 NNS denotes Cells
T10784 925-929 VBD denotes were
T10785 930-940 VBN denotes enumerated
T10786 941-943 IN denotes by
T10787 944-950 NN denotes trypan
T10788 951-955 JJ denotes blue
T10789 956-965 NN denotes exclusion
T10790 966-971 VBG denotes using
T10791 972-975 DT denotes the
T10792 976-984 NNP denotes Countess
T10793 985-994 VBN denotes automated
T10794 995-999 NN denotes cell
T10795 1000-1007 NN denotes counter
T10796 1008-1009 -LRB- denotes (
T10797 1009-1019 NNP denotes Invitrogen
T10798 1019-1020 -RRB- denotes )
T10799 1020-1021 . denotes .
T10800 1022-1025 IN denotes For
T10801 1026-1036 NN denotes derivation
T10802 1037-1039 IN denotes of
T10803 1040-1051 NNS denotes macrophages
T10804 1052-1056 IN denotes from
T10805 1057-1066 NNS denotes monocytes
T10806 1066-1067 , denotes ,
T10807 1068-1077 NNS denotes monocytes
T10808 1078-1082 VBD denotes were
T10809 1083-1090 VBN denotes allowed
T10810 1091-1093 TO denotes to
T10811 1094-1100 VB denotes adhere
T10812 1101-1103 TO denotes to
T10813 1104-1111 NN denotes plastic
T10814 1112-1115 IN denotes for
T10815 1116-1117 CD denotes 2
T10816 1118-1123 NNS denotes hours
T10817 1124-1126 IN denotes in
T10818 1127-1131 NNP denotes RPMI
T10819 1132-1136 CD denotes 1640
T10820 1137-1142 IN denotes after
T10821 1143-1148 WDT denotes which
T10822 1149-1161 JJ denotes non-adherent
T10823 1162-1167 NNS denotes cells
T10824 1168-1172 VBD denotes were
T10825 1173-1180 VBN denotes removed
T10826 1180-1181 . denotes .
T10827 1182-1191 NNS denotes Monocytes
T10828 1192-1196 VBD denotes were
T10829 1197-1204 VBN denotes allowed
T10830 1205-1207 TO denotes to
T10831 1208-1221 VB denotes differentiate
T10832 1222-1224 IN denotes in
T10833 1225-1229 NNP denotes RPMI
T10834 1230-1234 CD denotes 1640
T10835 1235-1247 VBN denotes supplemented
T10836 1248-1252 IN denotes with
T10837 1253-1255 CD denotes 10
T10838 1255-1256 NN denotes %
T10839 1257-1262 JJ denotes human
T10840 1263-1265 NNP denotes AB
T10841 1266-1271 NN denotes serum
T10842 1272-1275 IN denotes for
T10843 1276-1278 CD denotes 10
T10844 1279-1283 NNS denotes days
T10845 1283-1284 . denotes .
R9348 T10630 T10640 nsubjpass CF,established
R9349 T10631 T10630 cc and,CF
R9350 T10632 T10633 nsubj control,subject
R9351 T10633 T10640 advcl subject,established
R9352 T10634 T10633 dobj PBMCs,subject
R9353 T10635 T10636 det The,diagnosis
R9354 T10636 T10640 nsubjpass diagnosis,established
R9355 T10637 T10636 prep of,diagnosis
R9356 T10638 T10637 pobj CF,of
R9357 T10639 T10640 auxpass was,established
R9358 T10640 T10640 ROOT established,established
R9359 T10641 T10640 agent by,established
R9360 T10642 T10644 amod typical,features
R9361 T10643 T10644 amod clinical,features
R9362 T10644 T10641 pobj features,by
R9363 T10645 T10640 punct ",",established
R9364 T10646 T10640 dep increased,established
R9365 T10647 T10648 compound sweat,chloride
R9366 T10648 T10649 compound chloride,concentrations
R9367 T10649 T10646 dobj concentrations,increased
R9368 T10650 T10649 punct (,concentrations
R9369 T10651 T10649 appos >,concentrations
R9370 T10652 T10653 nummod 60,mmol/l
R9371 T10653 T10651 appos mmol/l,>
R9372 T10654 T10653 punct ),mmol/l
R9373 T10655 T10651 punct ",",>
R9374 T10656 T10651 cc and,>
R9375 T10657 T10651 conj detection,>
R9376 T10658 T10657 prep of,detection
R9377 T10659 T10660 amod CF-inducing,mutations
R9378 T10660 T10658 pobj mutations,of
R9379 T10661 T10640 punct .,established
R9380 T10662 T10663 det All,patients
R9381 T10663 T10666 nsubj patients,were
R9382 T10664 T10663 prep with,patients
R9383 T10665 T10664 pobj CF,with
R9384 T10666 T10666 ROOT were,were
R9385 T10667 T10668 advmod clinically,stable
R9386 T10668 T10666 acomp stable,were
R9387 T10669 T10666 prep at,were
R9388 T10670 T10671 det the,time
R9389 T10671 T10669 pobj time,at
R9390 T10672 T10671 prep of,time
R9391 T10673 T10674 compound blood,donation
R9392 T10674 T10672 pobj donation,of
R9393 T10675 T10666 punct ",",were
R9394 T10676 T10666 cc and,were
R9395 T10677 T10678 nsubj we,excluded
R9396 T10678 T10666 conj excluded,were
R9397 T10679 T10680 det any,subjects
R9398 T10680 T10678 dobj subjects,excluded
R9399 T10681 T10683 nsubj who,receiving
R9400 T10682 T10683 aux were,receiving
R9401 T10683 T10680 relcl receiving,subjects
R9402 T10684 T10685 amod systemic,corticosteroids
R9403 T10685 T10683 dobj corticosteroids,receiving
R9404 T10686 T10680 amod due,subjects
R9405 T10687 T10686 prep to,due
R9406 T10688 T10690 amod potential,activity
R9407 T10689 T10690 amod immunomodulatory,activity
R9408 T10690 T10687 pobj activity,to
R9409 T10691 T10678 punct .,excluded
R9410 T10692 T10693 compound Control,samples
R9411 T10693 T10695 nsubjpass samples,provided
R9412 T10694 T10695 auxpass were,provided
R9413 T10695 T10695 ROOT provided,provided
R9414 T10696 T10695 agent by,provided
R9415 T10697 T10699 amod healthy,volunteers
R9416 T10698 T10699 compound adult,volunteers
R9417 T10699 T10696 pobj volunteers,by
R9418 T10700 T10695 punct .,provided
R9419 T10701 T10707 prep In,demonstrated
R9420 T10702 T10703 advmod previously,published
R9421 T10703 T10704 amod published,work
R9422 T10704 T10701 pobj work,In
R9423 T10705 T10707 nsubj we,demonstrated
R9424 T10706 T10707 aux have,demonstrated
R9425 T10707 T10729 ccomp demonstrated,age-match
R9426 T10708 T10712 mark that,are
R9427 T10709 T10711 amod TLR-mediated,responses
R9428 T10710 T10711 amod inflammatory,responses
R9429 T10711 T10712 nsubj responses,are
R9430 T10712 T10707 ccomp are,demonstrated
R9431 T10713 T10712 acomp stable,are
R9432 T10714 T10713 prep in,stable
R9433 T10715 T10714 pobj humans,in
R9434 T10716 T10712 prep from,are
R9435 T10717 T10716 pobj birth,from
R9436 T10718 T10712 prep to,are
R9437 T10719 T10720 nummod 60,years
R9438 T10720 T10721 npadvmod years,old
R9439 T10721 T10718 amod old,to
R9440 T10722 T10724 nmod [,]
R9441 T10723 T10724 nummod 63,]
R9442 T10724 T10718 pobj ],to
R9443 T10725 T10729 punct ",",age-match
R9444 T10726 T10729 advmod therefore,age-match
R9445 T10727 T10729 aux did,age-match
R9446 T10728 T10729 neg not,age-match
R9447 T10729 T10729 ROOT age-match,age-match
R9448 T10730 T10732 det the,patients
R9449 T10731 T10732 compound CF,patients
R9450 T10732 T10729 dobj patients,age-match
R9451 T10733 T10732 cc and,patients
R9452 T10734 T10735 compound control,subjects
R9453 T10735 T10732 conj subjects,patients
R9454 T10736 T10729 punct .,age-match
R9455 T10737 T10738 amod Peripheral,blood
R9456 T10738 T10740 nsubjpass blood,collected
R9457 T10739 T10740 auxpass was,collected
R9458 T10740 T10740 ROOT collected,collected
R9459 T10741 T10740 prep in,collected
R9460 T10742 T10743 compound sodium,heparin
R9461 T10743 T10744 compound heparin,tubes
R9462 T10744 T10741 pobj tubes,in
R9463 T10745 T10747 punct (,Biosciences
R9464 T10746 T10747 compound BD,Biosciences
R9465 T10747 T10744 appos Biosciences,tubes
R9466 T10748 T10747 punct ),Biosciences
R9467 T10749 T10747 cc and,Biosciences
R9468 T10750 T10747 conj PBMCs,Biosciences
R9469 T10751 T10740 auxpass were,collected
R9470 T10752 T10751 acomp isolated,were
R9471 T10753 T10752 advcl using,isolated
R9472 T10754 T10756 nmod density,centrifugation
R9473 T10755 T10756 compound gradient,centrifugation
R9474 T10756 T10753 dobj centrifugation,using
R9475 T10757 T10756 prep on,centrifugation
R9476 T10758 T10760 compound Ficoll-Paque,Plus
R9477 T10759 T10760 compound ™,Plus
R9478 T10760 T10757 pobj Plus,on
R9479 T10761 T10760 punct (,Plus
R9480 T10762 T10763 compound GE,Healthcare
R9481 T10763 T10760 appos Healthcare,Plus
R9482 T10764 T10760 punct ),Plus
R9483 T10765 T10740 punct .,collected
R9484 T10766 T10767 det The,layer
R9485 T10767 T10770 nsubj layer,was
R9486 T10768 T10767 acl containing,layer
R9487 T10769 T10768 dobj PBMCs,containing
R9488 T10770 T10770 ROOT was,was
R9489 T10771 T10770 acomp isolated,was
R9490 T10772 T10771 punct ",",isolated
R9491 T10773 T10771 conj washed,isolated
R9492 T10774 T10773 advmod twice,washed
R9493 T10775 T10773 prep in,washed
R9494 T10776 T10775 pobj PBS,in
R9495 T10777 T10773 cc and,washed
R9496 T10778 T10773 conj resuspended,washed
R9497 T10779 T10778 prep in,resuspended
R9498 T10780 T10781 amod complete,RPMI
R9499 T10781 T10779 pobj RPMI,in
R9500 T10782 T10770 punct .,was
R9501 T10783 T10785 nsubjpass Cells,enumerated
R9502 T10784 T10785 auxpass were,enumerated
R9503 T10785 T10785 ROOT enumerated,enumerated
R9504 T10786 T10785 agent by,enumerated
R9505 T10787 T10789 amod trypan,exclusion
R9506 T10788 T10789 amod blue,exclusion
R9507 T10789 T10786 pobj exclusion,by
R9508 T10790 T10785 advcl using,enumerated
R9509 T10791 T10795 det the,counter
R9510 T10792 T10795 nmod Countess,counter
R9511 T10793 T10795 amod automated,counter
R9512 T10794 T10795 compound cell,counter
R9513 T10795 T10790 dobj counter,using
R9514 T10796 T10795 punct (,counter
R9515 T10797 T10795 appos Invitrogen,counter
R9516 T10798 T10795 punct ),counter
R9517 T10799 T10785 punct .,enumerated
R9518 T10800 T10809 prep For,allowed
R9519 T10801 T10800 pobj derivation,For
R9520 T10802 T10801 prep of,derivation
R9521 T10803 T10802 pobj macrophages,of
R9522 T10804 T10801 prep from,derivation
R9523 T10805 T10804 pobj monocytes,from
R9524 T10806 T10809 punct ",",allowed
R9525 T10807 T10809 nsubjpass monocytes,allowed
R9526 T10808 T10809 auxpass were,allowed
R9527 T10809 T10809 ROOT allowed,allowed
R9528 T10810 T10811 aux to,adhere
R9529 T10811 T10809 xcomp adhere,allowed
R9530 T10812 T10811 prep to,adhere
R9531 T10813 T10812 pobj plastic,to
R9532 T10814 T10811 prep for,adhere
R9533 T10815 T10816 nummod 2,hours
R9534 T10816 T10814 pobj hours,for
R9535 T10817 T10811 prep in,adhere
R9536 T10818 T10817 pobj RPMI,in
R9537 T10819 T10825 dep 1640,removed
R9538 T10820 T10825 prep after,removed
R9539 T10821 T10820 pobj which,after
R9540 T10822 T10823 amod non-adherent,cells
R9541 T10823 T10825 nsubjpass cells,removed
R9542 T10824 T10825 auxpass were,removed
R9543 T10825 T10809 advcl removed,allowed
R9544 T10826 T10809 punct .,allowed
R9545 T10827 T10829 nsubjpass Monocytes,allowed
R9546 T10828 T10829 auxpass were,allowed
R9547 T10829 T10829 ROOT allowed,allowed
R9548 T10830 T10831 aux to,differentiate
R9549 T10831 T10829 xcomp differentiate,allowed
R9550 T10832 T10831 prep in,differentiate
R9551 T10833 T10834 compound RPMI,1640
R9552 T10834 T10832 pobj 1640,in
R9553 T10835 T10829 conj supplemented,allowed
R9554 T10836 T10835 prep with,supplemented
R9555 T10837 T10838 nummod 10,%
R9556 T10838 T10841 compound %,serum
R9557 T10839 T10840 compound human,AB
R9558 T10840 T10841 compound AB,serum
R9559 T10841 T10836 pobj serum,with
R9560 T10842 T10835 prep for,supplemented
R9561 T10843 T10844 nummod 10,days
R9562 T10844 T10842 pobj days,for
R9563 T10845 T10829 punct .,allowed

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T10424 0-2 NN denotes CF
T10425 3-6 CC denotes and
T10426 7-14 NN denotes control
T10427 15-22 NN denotes subject
T10428 23-28 NN denotes PBMCs
T10429 29-32 DT denotes The
T10430 33-42 NN denotes diagnosis
T10431 43-45 IN denotes of
T10432 46-48 NN denotes CF
T10433 49-52 VB denotes was
T10434 53-64 VB denotes established
T10435 65-67 IN denotes by
T10436 68-75 JJ denotes typical
T10437 76-84 JJ denotes clinical
T10438 85-93 NN denotes features
T10439 93-94 -COMMA- denotes ,
T10440 95-104 VB denotes increased
T10441 105-110 NN denotes sweat
T10442 111-119 NN denotes chloride
T10443 120-134 NN denotes concentrations
T10444 135-136 -LRB- denotes (
T10445 136-137 SYM denotes >
T10446 137-139 CD denotes 60
T10447 140-146 NN denotes mmol/l
T10448 146-147 -RRB- denotes )
T10449 147-148 -COMMA- denotes ,
T10450 149-152 CC denotes and
T10451 153-162 NN denotes detection
T10452 163-165 IN denotes of
T10453 166-177 JJ denotes CF-inducing
T10454 178-187 NN denotes mutations
T10455 189-192 DT denotes All
T10456 193-201 NN denotes patients
T10457 202-206 IN denotes with
T10458 207-209 NN denotes CF
T10459 210-214 VB denotes were
T10460 215-225 RB denotes clinically
T10461 226-232 JJ denotes stable
T10462 233-235 IN denotes at
T10463 236-239 DT denotes the
T10464 240-244 NN denotes time
T10465 245-247 IN denotes of
T10466 248-253 NN denotes blood
T10467 254-262 NN denotes donation
T10468 262-263 -COMMA- denotes ,
T10469 264-267 CC denotes and
T10470 268-270 PRP denotes we
T10471 271-279 VB denotes excluded
T10472 280-283 DT denotes any
T10473 284-292 NN denotes subjects
T10474 293-296 WP denotes who
T10475 297-301 VB denotes were
T10476 302-311 VB denotes receiving
T10477 312-320 JJ denotes systemic
T10478 321-336 NN denotes corticosteroids
T10479 337-340 JJ denotes due
T10480 341-343 TO denotes to
T10481 344-353 JJ denotes potential
T10482 354-370 JJ denotes immunomodulatory
T10483 371-379 NN denotes activity
T10484 381-388 NN denotes Control
T10485 389-396 NN denotes samples
T10486 397-401 VB denotes were
T10487 402-410 VB denotes provided
T10488 411-413 IN denotes by
T10489 414-421 JJ denotes healthy
T10490 422-427 JJ denotes adult
T10491 428-438 NN denotes volunteers
T10492 440-442 IN denotes In
T10493 443-453 RB denotes previously
T10494 454-463 VB denotes published
T10495 464-468 NN denotes work
T10496 469-471 PRP denotes we
T10497 472-476 VB denotes have
T10498 477-489 VB denotes demonstrated
T10499 490-494 IN denotes that
T10500 495-507 JJ denotes TLR-mediated
T10501 508-520 JJ denotes inflammatory
T10502 521-530 NN denotes responses
T10503 531-534 VB denotes are
T10504 535-541 JJ denotes stable
T10505 542-544 IN denotes in
T10506 545-551 NN denotes humans
T10507 552-556 IN denotes from
T10508 557-562 NN denotes birth
T10509 563-565 TO denotes to
T10510 566-568 CD denotes 60
T10511 569-574 NN denotes years
T10512 575-578 JJ denotes old
T10513 579-580 -LRB- denotes [
T10514 580-582 CD denotes 63
T10515 582-583 -RRB- denotes ]
T10516 583-584 -COMMA- denotes ,
T10517 585-594 RB denotes therefore
T10518 595-598 VB denotes did
T10519 599-602 RB denotes not
T10520 603-612 VB denotes age-match
T10521 613-616 DT denotes the
T10522 617-619 NN denotes CF
T10523 620-628 NN denotes patients
T10524 629-632 CC denotes and
T10525 633-640 JJ denotes control
T10526 641-649 NN denotes subjects
T10527 651-661 JJ denotes Peripheral
T10528 662-667 NN denotes blood
T10529 668-671 VB denotes was
T10530 672-681 VB denotes collected
T10531 682-684 IN denotes in
T10532 685-691 NN denotes sodium
T10533 692-699 NN denotes heparin
T10534 700-705 NN denotes tubes
T10535 706-707 -LRB- denotes (
T10536 707-709 NN denotes BD
T10537 710-721 NNP denotes Biosciences
T10538 721-722 -RRB- denotes )
T10539 723-726 CC denotes and
T10540 727-732 NN denotes PBMCs
T10541 733-737 VB denotes were
T10542 738-746 VB denotes isolated
T10543 747-752 VB denotes using
T10544 753-760 NN denotes density
T10545 761-769 NN denotes gradient
T10546 770-784 NN denotes centrifugation
T10547 785-787 IN denotes on
T10548 788-801 JJ denotes Ficoll-Paque™
T10549 802-806 NN denotes Plus
T10550 807-808 -LRB- denotes (
T10551 808-810 NNP denotes GE
T10552 811-821 NNP denotes Healthcare
T10553 821-822 -RRB- denotes )
T10554 824-827 DT denotes The
T10555 828-833 NN denotes layer
T10556 834-844 VB denotes containing
T10557 845-850 NN denotes PBMCs
T10558 851-854 VB denotes was
T10559 855-863 VB denotes isolated
T10560 863-864 -COMMA- denotes ,
T10561 865-871 VB denotes washed
T10562 872-877 RB denotes twice
T10563 878-880 IN denotes in
T10564 881-884 NNP denotes PBS
T10565 885-888 CC denotes and
T10566 889-900 VB denotes resuspended
T10567 901-903 IN denotes in
T10568 904-912 JJ denotes complete
T10569 913-917 NN denotes RPMI
T10570 919-924 NN denotes Cells
T10571 925-929 VB denotes were
T10572 930-940 VB denotes enumerated
T10573 941-943 IN denotes by
T10574 944-950 NN denotes trypan
T10575 951-955 JJ denotes blue
T10576 956-965 NN denotes exclusion
T10577 966-971 VB denotes using
T10578 972-975 DT denotes the
T10579 976-984 NNP denotes Countess
T10580 985-994 VB denotes automated
T10581 995-999 NN denotes cell
T10582 1000-1007 NN denotes counter
T10583 1008-1009 -LRB- denotes (
T10584 1009-1019 NN denotes Invitrogen
T10585 1019-1020 -RRB- denotes )
T10586 1022-1025 IN denotes For
T10587 1026-1036 NN denotes derivation
T10588 1037-1039 IN denotes of
T10589 1040-1051 NN denotes macrophages
T10590 1052-1056 IN denotes from
T10591 1057-1066 NN denotes monocytes
T10592 1066-1067 -COMMA- denotes ,
T10593 1068-1077 NN denotes monocytes
T10594 1078-1082 VB denotes were
T10595 1083-1090 VB denotes allowed
T10596 1091-1093 TO denotes to
T10597 1094-1100 VB denotes adhere
T10598 1101-1103 TO denotes to
T10599 1104-1111 NN denotes plastic
T10600 1112-1115 IN denotes for
T10601 1116-1117 CD denotes 2
T10602 1118-1123 NN denotes hours
T10603 1124-1126 IN denotes in
T10604 1127-1131 NN denotes RPMI
T10605 1132-1136 CD denotes 1640
T10606 1137-1142 IN denotes after
T10607 1143-1148 WDT denotes which
T10608 1149-1161 JJ denotes non-adherent
T10609 1162-1167 NN denotes cells
T10610 1168-1172 VB denotes were
T10611 1173-1180 VB denotes removed
T10612 1182-1191 NN denotes Monocytes
T10613 1192-1196 VB denotes were
T10614 1197-1204 VB denotes allowed
T10615 1205-1207 TO denotes to
T10616 1208-1221 VB denotes differentiate
T10617 1222-1224 IN denotes in
T10618 1225-1229 NN denotes RPMI
T10619 1230-1234 CD denotes 1640
T10620 1235-1247 VB denotes supplemented
T10621 1248-1252 IN denotes with
T10622 1253-1255 CD denotes 10
T10623 1255-1256 NN denotes %
T10624 1257-1262 JJ denotes human
T10625 1263-1265 NN denotes AB
T10626 1266-1271 NN denotes serum
T10627 1272-1275 IN denotes for
T10628 1276-1278 CD denotes 10
T10629 1279-1283 NN denotes days
R9132 T10424 T10425 arg1Of CF,and
R9133 T10426 T10425 arg2Of control,and
R9134 T10428 T10424 arg1Of PBMCs,CF
R9135 T10428 T10426 arg1Of PBMCs,control
R9136 T10428 T10427 arg1Of PBMCs,subject
R9137 T10430 T10429 arg1Of diagnosis,The
R9138 T10430 T10431 arg1Of diagnosis,of
R9139 T10430 T10433 arg1Of diagnosis,was
R9140 T10430 T10434 arg2Of diagnosis,established
R9141 T10432 T10431 arg2Of CF,of
R9142 T10434 T10433 arg2Of established,was
R9143 T10438 T10436 arg1Of features,typical
R9144 T10438 T10437 arg1Of features,clinical
R9145 T10438 T10439 arg1Of features,","
R9146 T10439 T10450 arg1Of ",",and
R9147 T10443 T10439 arg2Of concentrations,","
R9148 T10443 T10440 arg2Of concentrations,increased
R9149 T10443 T10441 arg1Of concentrations,sweat
R9150 T10443 T10442 arg1Of concentrations,chloride
R9151 T10443 T10444 arg1Of concentrations,(
R9152 T10446 T10445 arg1Of 60,>
R9153 T10447 T10444 arg2Of mmol/l,(
R9154 T10447 T10446 arg1Of mmol/l,60
R9155 T10448 T10444 arg3Of ),(
R9156 T10450 T10434 arg1Of and,established
R9157 T10450 T10435 arg2Of and,by
R9158 T10450 T10449 arg1Of and,","
R9159 T10451 T10450 arg2Of detection,and
R9160 T10451 T10452 arg1Of detection,of
R9161 T10454 T10452 arg2Of mutations,of
R9162 T10454 T10453 arg1Of mutations,CF-inducing
R9163 T10456 T10455 arg1Of patients,All
R9164 T10456 T10457 arg1Of patients,with
R9165 T10456 T10459 arg1Of patients,were
R9166 T10456 T10461 arg1Of patients,stable
R9167 T10458 T10457 arg2Of CF,with
R9168 T10459 T10469 arg1Of were,and
R9169 T10461 T10459 arg2Of stable,were
R9170 T10461 T10460 arg1Of stable,clinically
R9171 T10461 T10462 arg1Of stable,at
R9172 T10464 T10462 arg2Of time,at
R9173 T10464 T10463 arg1Of time,the
R9174 T10464 T10465 arg1Of time,of
R9175 T10467 T10465 arg2Of donation,of
R9176 T10467 T10466 arg1Of donation,blood
R9177 T10469 T10468 arg1Of and,","
R9178 T10470 T10471 arg1Of we,excluded
R9179 T10471 T10469 arg2Of excluded,and
R9180 T10473 T10471 arg2Of subjects,excluded
R9181 T10473 T10472 arg1Of subjects,any
R9182 T10473 T10474 arg1Of subjects,who
R9183 T10473 T10475 arg1Of subjects,were
R9184 T10473 T10476 arg1Of subjects,receiving
R9185 T10476 T10475 arg2Of receiving,were
R9186 T10478 T10476 arg2Of corticosteroids,receiving
R9187 T10478 T10477 arg1Of corticosteroids,systemic
R9188 T10478 T10479 arg1Of corticosteroids,due
R9189 T10479 T10480 arg1Of due,to
R9190 T10483 T10480 arg2Of activity,to
R9191 T10483 T10481 arg1Of activity,potential
R9192 T10483 T10482 arg1Of activity,immunomodulatory
R9193 T10485 T10484 arg1Of samples,Control
R9194 T10485 T10486 arg1Of samples,were
R9195 T10485 T10487 arg2Of samples,provided
R9196 T10487 T10486 arg2Of provided,were
R9197 T10490 T10489 arg1Of adult,healthy
R9198 T10491 T10487 arg1Of volunteers,provided
R9199 T10491 T10488 arg2Of volunteers,by
R9200 T10491 T10490 arg1Of volunteers,adult
R9201 T10494 T10493 arg1Of published,previously
R9202 T10495 T10492 arg2Of work,In
R9203 T10495 T10494 arg1Of work,published
R9204 T10496 T10497 arg1Of we,have
R9205 T10496 T10498 arg1Of we,demonstrated
R9206 T10498 T10492 arg1Of demonstrated,In
R9207 T10498 T10497 arg2Of demonstrated,have
R9208 T10502 T10500 arg1Of responses,TLR-mediated
R9209 T10502 T10501 arg1Of responses,inflammatory
R9210 T10502 T10503 arg1Of responses,are
R9211 T10502 T10504 arg1Of responses,stable
R9212 T10502 T10518 arg1Of responses,did
R9213 T10502 T10520 arg1Of responses,age-match
R9214 T10503 T10516 arg1Of are,","
R9215 T10504 T10503 arg2Of stable,are
R9216 T10504 T10505 arg1Of stable,in
R9217 T10506 T10505 arg2Of humans,in
R9218 T10506 T10507 arg1Of humans,from
R9219 T10508 T10507 arg2Of birth,from
R9220 T10508 T10512 arg1Of birth,old
R9221 T10508 T10513 arg1Of birth,[
R9222 T10511 T10510 arg1Of years,60
R9223 T10512 T10509 arg1Of old,to
R9224 T10512 T10511 arg1Of old,years
R9225 T10514 T10513 arg2Of 63,[
R9226 T10515 T10513 arg3Of ],[
R9227 T10516 T10498 arg2Of ",",demonstrated
R9228 T10516 T10499 arg1Of ",",that
R9229 T10520 T10516 arg2Of age-match,","
R9230 T10520 T10517 arg1Of age-match,therefore
R9231 T10520 T10518 arg2Of age-match,did
R9232 T10520 T10519 arg1Of age-match,not
R9233 T10523 T10522 arg1Of patients,CF
R9234 T10523 T10524 arg1Of patients,and
R9235 T10524 T10520 arg2Of and,age-match
R9236 T10524 T10521 arg1Of and,the
R9237 T10526 T10524 arg2Of subjects,and
R9238 T10526 T10525 arg1Of subjects,control
R9239 T10528 T10527 arg1Of blood,Peripheral
R9240 T10528 T10529 arg1Of blood,was
R9241 T10528 T10530 arg2Of blood,collected
R9242 T10530 T10529 arg2Of collected,was
R9243 T10530 T10531 arg1Of collected,in
R9244 T10530 T10539 arg1Of collected,and
R9245 T10534 T10531 arg2Of tubes,in
R9246 T10534 T10532 arg1Of tubes,sodium
R9247 T10534 T10533 arg1Of tubes,heparin
R9248 T10534 T10535 arg1Of tubes,(
R9249 T10537 T10535 arg2Of Biosciences,(
R9250 T10537 T10536 arg1Of Biosciences,BD
R9251 T10538 T10535 arg3Of ),(
R9252 T10540 T10541 arg1Of PBMCs,were
R9253 T10540 T10542 arg2Of PBMCs,isolated
R9254 T10542 T10539 arg2Of isolated,and
R9255 T10542 T10541 arg2Of isolated,were
R9256 T10542 T10543 modOf isolated,using
R9257 T10546 T10543 arg2Of centrifugation,using
R9258 T10546 T10544 arg1Of centrifugation,density
R9259 T10546 T10545 arg1Of centrifugation,gradient
R9260 T10546 T10547 arg1Of centrifugation,on
R9261 T10549 T10547 arg2Of Plus,on
R9262 T10549 T10548 arg1Of Plus,Ficoll-Paque™
R9263 T10549 T10550 arg1Of Plus,(
R9264 T10552 T10550 arg2Of Healthcare,(
R9265 T10552 T10551 arg1Of Healthcare,GE
R9266 T10553 T10550 arg3Of ),(
R9267 T10557 T10554 arg1Of PBMCs,The
R9268 T10557 T10555 arg1Of PBMCs,layer
R9269 T10557 T10556 arg1Of PBMCs,containing
R9270 T10557 T10558 arg1Of PBMCs,was
R9271 T10557 T10559 arg2Of PBMCs,isolated
R9272 T10557 T10561 arg2Of PBMCs,washed
R9273 T10557 T10566 arg1Of PBMCs,resuspended
R9274 T10559 T10560 arg1Of isolated,","
R9275 T10560 T10565 arg1Of ",",and
R9276 T10561 T10560 arg2Of washed,","
R9277 T10561 T10562 arg1Of washed,twice
R9278 T10561 T10563 arg1Of washed,in
R9279 T10564 T10563 arg2Of PBS,in
R9280 T10565 T10558 arg2Of and,was
R9281 T10566 T10565 arg2Of resuspended,and
R9282 T10566 T10567 arg1Of resuspended,in
R9283 T10569 T10567 arg2Of RPMI,in
R9284 T10569 T10568 arg1Of RPMI,complete
R9285 T10570 T10571 arg1Of Cells,were
R9286 T10570 T10572 arg2Of Cells,enumerated
R9287 T10572 T10571 arg2Of enumerated,were
R9288 T10576 T10572 arg1Of exclusion,enumerated
R9289 T10576 T10573 arg2Of exclusion,by
R9290 T10576 T10574 arg1Of exclusion,trypan
R9291 T10576 T10575 arg1Of exclusion,blue
R9292 T10576 T10577 arg1Of exclusion,using
R9293 T10582 T10577 arg2Of counter,using
R9294 T10582 T10578 arg1Of counter,the
R9295 T10582 T10579 arg1Of counter,Countess
R9296 T10582 T10580 arg2Of counter,automated
R9297 T10582 T10581 arg1Of counter,cell
R9298 T10582 T10583 arg1Of counter,(
R9299 T10584 T10583 arg2Of Invitrogen,(
R9300 T10585 T10583 arg3Of ),(
R9301 T10587 T10586 arg2Of derivation,For
R9302 T10587 T10588 arg1Of derivation,of
R9303 T10587 T10590 arg1Of derivation,from
R9304 T10589 T10588 arg2Of macrophages,of
R9305 T10591 T10590 arg2Of monocytes,from
R9306 T10593 T10594 arg1Of monocytes,were
R9307 T10593 T10595 arg2Of monocytes,allowed
R9308 T10593 T10597 arg1Of monocytes,adhere
R9309 T10595 T10586 arg1Of allowed,For
R9310 T10595 T10592 arg1Of allowed,","
R9311 T10595 T10594 arg2Of allowed,were
R9312 T10597 T10595 arg3Of adhere,allowed
R9313 T10597 T10596 arg1Of adhere,to
R9314 T10597 T10598 arg1Of adhere,to
R9315 T10597 T10600 arg1Of adhere,for
R9316 T10599 T10598 arg2Of plastic,to
R9317 T10602 T10600 arg2Of hours,for
R9318 T10602 T10601 arg1Of hours,2
R9319 T10602 T10603 arg1Of hours,in
R9320 T10602 T10606 arg2Of hours,after
R9321 T10602 T10607 arg1Of hours,which
R9322 T10604 T10603 arg2Of RPMI,in
R9323 T10604 T10605 arg1Of RPMI,1640
R9324 T10609 T10608 arg1Of cells,non-adherent
R9325 T10609 T10610 arg1Of cells,were
R9326 T10609 T10611 arg2Of cells,removed
R9327 T10611 T10606 arg1Of removed,after
R9328 T10611 T10610 arg2Of removed,were
R9329 T10612 T10613 arg1Of Monocytes,were
R9330 T10612 T10614 arg2Of Monocytes,allowed
R9331 T10612 T10616 arg1Of Monocytes,differentiate
R9332 T10614 T10613 arg2Of allowed,were
R9333 T10616 T10614 arg3Of differentiate,allowed
R9334 T10616 T10615 arg1Of differentiate,to
R9335 T10616 T10617 arg1Of differentiate,in
R9336 T10616 T10627 arg1Of differentiate,for
R9337 T10618 T10617 arg2Of RPMI,in
R9338 T10618 T10619 arg1Of RPMI,1640
R9339 T10618 T10620 arg2Of RPMI,supplemented
R9340 T10620 T10621 arg1Of supplemented,with
R9341 T10622 T10623 arg1Of 10,%
R9342 T10626 T10621 arg2Of serum,with
R9343 T10626 T10622 arg1Of serum,10
R9344 T10626 T10624 arg1Of serum,human
R9345 T10626 T10625 arg1Of serum,AB
R9346 T10629 T10627 arg2Of days,for
R9347 T10629 T10628 arg1Of days,10

sentences

Id Subject Object Predicate Lexical cue
T10414 0-28 Sentence denotes CF and control subject PBMCs
T10415 29-188 Sentence denotes The diagnosis of CF was established by typical clinical features, increased sweat chloride concentrations (>60 mmol/l), and detection of CF-inducing mutations.
T10416 189-380 Sentence denotes All patients with CF were clinically stable at the time of blood donation, and we excluded any subjects who were receiving systemic corticosteroids due to potential immunomodulatory activity.
T10417 381-439 Sentence denotes Control samples were provided by healthy adult volunteers.
T10418 440-650 Sentence denotes In previously published work we have demonstrated that TLR-mediated inflammatory responses are stable in humans from birth to 60 years old [63], therefore did not age-match the CF patients and control subjects.
T10419 651-823 Sentence denotes Peripheral blood was collected in sodium heparin tubes (BD Biosciences) and PBMCs were isolated using density gradient centrifugation on Ficoll-Paque™ Plus (GE Healthcare).
T10420 824-918 Sentence denotes The layer containing PBMCs was isolated, washed twice in PBS and resuspended in complete RPMI.
T10421 919-1021 Sentence denotes Cells were enumerated by trypan blue exclusion using the Countess automated cell counter (Invitrogen).
T10422 1022-1181 Sentence denotes For derivation of macrophages from monocytes, monocytes were allowed to adhere to plastic for 2 hours in RPMI 1640 after which non-adherent cells were removed.
T10423 1182-1284 Sentence denotes Monocytes were allowed to differentiate in RPMI 1640 supplemented with 10% human AB serum for 10 days.
T188 0-28 Sentence denotes CF and control subject PBMCs
T189 29-188 Sentence denotes The diagnosis of CF was established by typical clinical features, increased sweat chloride concentrations (>60 mmol/l), and detection of CF-inducing mutations.
T190 189-380 Sentence denotes All patients with CF were clinically stable at the time of blood donation, and we excluded any subjects who were receiving systemic corticosteroids due to potential immunomodulatory activity.
T191 381-439 Sentence denotes Control samples were provided by healthy adult volunteers.
T192 440-650 Sentence denotes In previously published work we have demonstrated that TLR-mediated inflammatory responses are stable in humans from birth to 60 years old [63], therefore did not age-match the CF patients and control subjects.
T193 651-823 Sentence denotes Peripheral blood was collected in sodium heparin tubes (BD Biosciences) and PBMCs were isolated using density gradient centrifugation on Ficoll-Paque™ Plus (GE Healthcare).
T194 824-918 Sentence denotes The layer containing PBMCs was isolated, washed twice in PBS and resuspended in complete RPMI.
T195 919-1021 Sentence denotes Cells were enumerated by trypan blue exclusion using the Countess automated cell counter (Invitrogen).
T196 1022-1181 Sentence denotes For derivation of macrophages from monocytes, monocytes were allowed to adhere to plastic for 2 hours in RPMI 1640 after which non-adherent cells were removed.
T197 1182-1284 Sentence denotes Monocytes were allowed to differentiate in RPMI 1640 supplemented with 10% human AB serum for 10 days.

2_test

Id Subject Object Predicate Lexical cue
22649552-17157070-88306747 580-582 17157070 denotes 63
T28787 580-582 17157070 denotes 63