PMC:3359311 / 14047-15230
Annnotations
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T14169 | 87-92 | P01584 | denotes | IL-1β |
| T14170 | 392-396 | P05412 | denotes | AP-1 |
| T14171 | 411-415 | P10145 | denotes | IL-8 |
| T14172 | 425-430 | P01584 | denotes | IL-1β |
| T14173 | 673-677 | P05412 | denotes | AP-1 |
| T14174 | 692-696 | P10145 | denotes | IL-8 |
| T14175 | 706-711 | P01584 | denotes | IL-1β |
| T14176 | 973-978 | P01584 | denotes | IL-1β |
| T14177 | 987-991 | P10145 | denotes | IL-8 |
bionlp-st-ge-2016-reference
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T13923 | 61-72 | Positive_regulation | denotes | potentiates | |
| T13924 | 61-72 | Positive_regulation | denotes | potentiates | |
| T13925 | 87-92 | Protein | denotes | IL-1β | |
| T13926 | 93-103 | Gene_expression | denotes | production | |
| T13927 | 108-117 | Localization | denotes | secretion | |
| T13928 | 118-122 | Positive_regulation | denotes | upon | |
| T13929 | 118-122 | Positive_regulation | denotes | upon | |
| T13930 | 425-430 | Protein | denotes | IL-1β | |
| T13931 | 431-440 | Localization | denotes | secretion | |
| T13932 | 706-711 | Protein | denotes | IL-1β | |
| T13933 | 712-721 | Localization | denotes | secretion | true |
| T13934 | 973-978 | Protein | denotes | IL-1β | |
| R12352 | T13923 | T13929 | themeOf | potentiates,upon | |
| R12353 | T13924 | T13928 | themeOf | potentiates,upon | |
| R12354 | T13925 | T13926 | themeOf | IL-1β,production | |
| R12355 | T13925 | T13927 | themeOf | IL-1β,secretion | |
| R12356 | T13926 | T13924 | themeOf | production,potentiates | |
| R12357 | T13927 | T13923 | themeOf | secretion,potentiates | |
| R12358 | T13930 | T13931 | themeOf | IL-1β,secretion | |
| R12359 | T13932 | T13933 | themeOf | IL-1β,secretion |
bionlp-st-ge-2016-reference-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T14485 | 44-49 | Protein | denotes | NF-κB |
| T14486 | 87-92 | Protein | denotes | IL-1β |
| T14487 | 50-60 | Positive_regulation | denotes | activation |
| T14488 | 93-103 | Gene_expression | denotes | production |
| T14489 | 77-83 | Negative_regulation | denotes | degree |
| T14490 | 61-72 | Positive_regulation | denotes | potentiates |
| T14491 | 389-391 | Protein | denotes | κB |
| T14492 | 392-396 | Protein | denotes | AP-1 |
| T14493 | 602-606 | Protein | denotes | PAO1 |
| T14494 | 615-619 | Protein | denotes | PAO1 |
| T14495 | 670-672 | Protein | denotes | κB |
| T14496 | 673-677 | Protein | denotes | AP-1 |
| T14497 | 706-711 | Protein | denotes | IL-1β |
| T14498 | 712-721 | Localization | denotes | secretion |
| T14499 | 712-721 | Localization | denotes | secretion |
| T14500 | 877-881 | Protein | denotes | PAO1 |
| T14501 | 973-978 | Protein | denotes | IL-1β |
| R12872 | T14485 | T14487 | themeOf | NF-κB,activation |
| R12873 | T14486 | T14488 | themeOf | IL-1β,production |
| R12874 | T14487 | T14490 | causeOf | activation,potentiates |
| R12875 | T14488 | T14489 | themeOf | production,degree |
| R12876 | T14489 | T14490 | themeOf | degree,potentiates |
| R12877 | T14495 | T14498 | themeOf | κB,secretion |
| R12878 | T14497 | T14499 | themeOf | IL-1β,secretion |
events-check-again
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T14473 | 61-72 | Positive_regulation | denotes | potentiates | |
| T14474 | 61-72 | Positive_regulation | denotes | potentiates | |
| T14475 | 87-92 | Protein | denotes | IL-1β | |
| T14476 | 93-103 | Gene_expression | denotes | production | |
| T14477 | 108-117 | Localization | denotes | secretion | |
| T14478 | 118-122 | Positive_regulation | denotes | upon | |
| T14479 | 118-122 | Positive_regulation | denotes | upon | |
| T14480 | 425-430 | Protein | denotes | IL-1β | |
| T14481 | 431-440 | Localization | denotes | secretion | |
| T14482 | 706-711 | Protein | denotes | IL-1β | |
| T14483 | 712-721 | Localization | denotes | secretion | true |
| T14484 | 973-978 | Protein | denotes | IL-1β | |
| R12864 | T14473 | T14479 | themeOf | potentiates,upon | |
| R12865 | T14474 | T14478 | themeOf | potentiates,upon | |
| R12866 | T14475 | T14476 | themeOf | IL-1β,production | |
| R12867 | T14475 | T14477 | themeOf | IL-1β,secretion | |
| R12868 | T14476 | T14474 | themeOf | production,potentiates | |
| R12869 | T14477 | T14473 | themeOf | secretion,potentiates | |
| R12870 | T14480 | T14481 | themeOf | IL-1β,secretion | |
| R12871 | T14482 | T14483 | themeOf | IL-1β,secretion |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T14444 | 163-168 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T14445 | 514-519 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T14446 | 411-415 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
| T14447 | 692-696 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
| T14448 | 987-991 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T14441 | 108-117 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T14442 | 431-440 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T14443 | 712-721 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T14178 | 44-49 | JJ | denotes | NF-κB |
| T14179 | 50-60 | NN | denotes | activation |
| T14180 | 61-72 | VBZ | denotes | potentiates |
| T14181 | 73-76 | DT | denotes | the |
| T14182 | 77-83 | NN | denotes | degree |
| T14183 | 84-86 | IN | denotes | of |
| T14184 | 87-92 | JJ | denotes | IL-1β |
| T14185 | 93-103 | NN | denotes | production |
| T14186 | 104-107 | CC | denotes | and |
| T14187 | 108-117 | NN | denotes | secretion |
| T14188 | 118-122 | IN | denotes | upon |
| T14189 | 123-135 | JJ | denotes | inflammasome |
| T14190 | 136-146 | NN | denotes | activation |
| T14191 | 146-147 | . | denotes | . |
| T14192 | 148-153 | CD | denotes | THP-1 |
| T14193 | 154-162 | NN | denotes | reporter |
| T14194 | 163-168 | NNS | denotes | cells |
| T14195 | 169-173 | VBD | denotes | were |
| T14196 | 174-180 | VBN | denotes | primed |
| T14197 | 181-190 | JJ | denotes | overnight |
| T14198 | 191-195 | IN | denotes | with |
| T14199 | 196-207 | JJ | denotes | heat-killed |
| T14200 | 208-210 | NNP | denotes | P. |
| T14201 | 211-221 | NN | denotes | aeruginosa |
| T14202 | 222-225 | CC | denotes | and |
| T14203 | 226-236 | VBD | denotes | stimulated |
| T14204 | 237-240 | DT | denotes | the |
| T14205 | 241-245 | JJ | denotes | next |
| T14206 | 246-249 | NN | denotes | day |
| T14207 | 250-254 | IN | denotes | with |
| T14208 | 255-259 | JJ | denotes | live |
| T14209 | 260-262 | NNP | denotes | P. |
| T14210 | 263-273 | NN | denotes | aeruginosa |
| T14211 | 274-276 | CC | denotes | or |
| T14212 | 277-287 | JJ | denotes | additional |
| T14213 | 288-299 | JJ | denotes | heat-killed |
| T14214 | 300-302 | NNP | denotes | P. |
| T14215 | 303-313 | NN | denotes | aeruginosa |
| T14216 | 314-317 | IN | denotes | for |
| T14217 | 318-321 | DT | denotes | the |
| T14218 | 322-327 | NNS | denotes | times |
| T14219 | 328-337 | VBD | denotes | indicated |
| T14220 | 337-338 | . | denotes | . |
| T14221 | 339-343 | NNP | denotes | Cell |
| T14222 | 344-351 | NN | denotes | culture |
| T14223 | 352-364 | NNS | denotes | supernatants |
| T14224 | 365-369 | VBD | denotes | were |
| T14225 | 370-377 | VBN | denotes | assayed |
| T14226 | 378-381 | IN | denotes | for |
| T14227 | 382-383 | -LRB- | denotes | ( |
| T14228 | 383-384 | NN | denotes | A |
| T14229 | 384-385 | -RRB- | denotes | ) |
| T14230 | 386-391 | NN | denotes | NF-κB |
| T14231 | 391-392 | NN | denotes | / |
| T14232 | 392-396 | NN | denotes | AP-1 |
| T14233 | 397-405 | NN | denotes | activity |
| T14234 | 405-406 | , | denotes | , |
| T14235 | 407-408 | -LRB- | denotes | ( |
| T14236 | 408-409 | NNP | denotes | B |
| T14237 | 409-410 | -RRB- | denotes | ) |
| T14238 | 411-415 | NN | denotes | IL-8 |
| T14239 | 415-416 | , | denotes | , |
| T14240 | 417-420 | CC | denotes | and |
| T14241 | 421-422 | -LRB- | denotes | ( |
| T14242 | 422-423 | NNP | denotes | C |
| T14243 | 423-424 | -RRB- | denotes | ) |
| T14244 | 425-430 | JJ | denotes | IL-1β |
| T14245 | 431-440 | NN | denotes | secretion |
| T14246 | 441-442 | -LRB- | denotes | ( |
| T14247 | 442-443 | FW | denotes | n |
| T14248 | 444-445 | SYM | denotes | = |
| T14249 | 446-447 | CD | denotes | 3 |
| T14250 | 448-449 | CD | denotes | 6 |
| T14251 | 450-461 | NNS | denotes | experiments |
| T14252 | 461-462 | -RRB- | denotes | ) |
| T14253 | 462-463 | . | denotes | . |
| T14254 | 464-469 | VBG | denotes | Using |
| T14255 | 470-473 | DT | denotes | the |
| T14256 | 474-478 | JJ | denotes | same |
| T14257 | 479-490 | NN | denotes | stimulation |
| T14258 | 491-497 | NN | denotes | method |
| T14259 | 497-498 | , | denotes | , |
| T14260 | 499-504 | CD | denotes | THP-1 |
| T14261 | 505-513 | NN | denotes | reporter |
| T14262 | 514-519 | NNS | denotes | cells |
| T14263 | 520-524 | VBD | denotes | were |
| T14264 | 525-532 | VBN | denotes | treated |
| T14265 | 533-537 | IN | denotes | with |
| T14266 | 538-548 | NN | denotes | Bay11-7082 |
| T14267 | 549-550 | -LRB- | denotes | ( |
| T14268 | 550-552 | CD | denotes | 20 |
| T14269 | 553-555 | NNP | denotes | µM |
| T14270 | 555-556 | -RRB- | denotes | ) |
| T14271 | 557-560 | IN | denotes | for |
| T14272 | 561-562 | CD | denotes | 1 |
| T14273 | 563-567 | NN | denotes | hour |
| T14274 | 568-573 | RB | denotes | prior |
| T14275 | 574-576 | TO | denotes | to |
| T14276 | 577-584 | VBG | denotes | priming |
| T14277 | 585-589 | IN | denotes | with |
| T14278 | 590-601 | JJ | denotes | heat-killed |
| T14279 | 602-606 | NNP | denotes | PAO1 |
| T14280 | 607-609 | CC | denotes | or |
| T14281 | 610-614 | JJ | denotes | live |
| T14282 | 615-619 | NN | denotes | PAO1 |
| T14283 | 619-620 | . | denotes | . |
| T14284 | 621-633 | NNS | denotes | Supernatants |
| T14285 | 634-638 | VBD | denotes | were |
| T14286 | 639-646 | VBN | denotes | assayed |
| T14287 | 647-649 | IN | denotes | at |
| T14288 | 650-652 | CD | denotes | 24 |
| T14289 | 653-658 | NNS | denotes | hours |
| T14290 | 659-662 | IN | denotes | for |
| T14291 | 663-664 | -LRB- | denotes | ( |
| T14292 | 664-665 | NNP | denotes | D |
| T14293 | 665-666 | -RRB- | denotes | ) |
| T14294 | 667-672 | NNP | denotes | NF-κB |
| T14295 | 672-673 | NNP | denotes | / |
| T14296 | 673-677 | NNP | denotes | AP-1 |
| T14297 | 678-686 | NN | denotes | activity |
| T14298 | 686-687 | , | denotes | , |
| T14299 | 688-689 | -LRB- | denotes | ( |
| T14300 | 689-690 | NNP | denotes | E |
| T14301 | 690-691 | -RRB- | denotes | ) |
| T14302 | 692-696 | NN | denotes | IL-8 |
| T14303 | 696-697 | , | denotes | , |
| T14304 | 698-701 | CC | denotes | and |
| T14305 | 702-703 | -LRB- | denotes | ( |
| T14306 | 703-704 | NN | denotes | F |
| T14307 | 704-705 | -RRB- | denotes | ) |
| T14308 | 706-711 | NN | denotes | IL-1β |
| T14309 | 712-721 | NN | denotes | secretion |
| T14310 | 722-723 | -LRB- | denotes | ( |
| T14311 | 723-724 | FW | denotes | n |
| T14312 | 725-726 | SYM | denotes | = |
| T14313 | 727-728 | CD | denotes | 3 |
| T14314 | 729-730 | LS | denotes | 5 |
| T14315 | 730-731 | -RRB- | denotes | ) |
| T14316 | 731-732 | . | denotes | . |
| T14317 | 733-738 | NNS | denotes | PBMCs |
| T14318 | 739-743 | IN | denotes | from |
| T14319 | 744-746 | NNP | denotes | CF |
| T14320 | 747-755 | NNS | denotes | patients |
| T14321 | 756-757 | -LRB- | denotes | ( |
| T14322 | 757-758 | FW | denotes | n |
| T14323 | 759-760 | SYM | denotes | = |
| T14324 | 761-763 | CD | denotes | 11 |
| T14325 | 764-766 | CD | denotes | 15 |
| T14326 | 766-767 | -RRB- | denotes | ) |
| T14327 | 768-771 | CC | denotes | and |
| T14328 | 772-780 | NNS | denotes | controls |
| T14329 | 781-782 | -LRB- | denotes | ( |
| T14330 | 782-783 | FW | denotes | n |
| T14331 | 784-785 | SYM | denotes | = |
| T14332 | 786-788 | CD | denotes | 10 |
| T14333 | 789-791 | CD | denotes | 13 |
| T14334 | 791-792 | -RRB- | denotes | ) |
| T14335 | 793-797 | VBD | denotes | were |
| T14336 | 798-805 | VBN | denotes | treated |
| T14337 | 806-810 | IN | denotes | with |
| T14338 | 811-821 | NNP | denotes | z-YVAD-fmk |
| T14339 | 822-823 | -LRB- | denotes | ( |
| T14340 | 823-825 | CD | denotes | 20 |
| T14341 | 826-828 | NNP | denotes | µM |
| T14342 | 828-829 | -RRB- | denotes | ) |
| T14343 | 830-832 | CC | denotes | or |
| T14344 | 833-843 | NN | denotes | Bay11-7082 |
| T14345 | 844-845 | -LRB- | denotes | ( |
| T14346 | 845-847 | CD | denotes | 10 |
| T14347 | 848-850 | NNP | denotes | µM |
| T14348 | 850-851 | -RRB- | denotes | ) |
| T14349 | 852-855 | CC | denotes | and |
| T14350 | 856-866 | VBN | denotes | stimulated |
| T14351 | 867-871 | IN | denotes | with |
| T14352 | 872-876 | JJ | denotes | live |
| T14353 | 877-881 | NNP | denotes | PAO1 |
| T14354 | 882-883 | -LRB- | denotes | ( |
| T14355 | 883-886 | NNP | denotes | MOI |
| T14356 | 887-888 | SYM | denotes | = |
| T14357 | 889-890 | LS | denotes | 1 |
| T14358 | 890-891 | -RRB- | denotes | ) |
| T14359 | 891-892 | , | denotes | , |
| T14360 | 893-896 | NNP | denotes | ATP |
| T14361 | 897-898 | -LRB- | denotes | ( |
| T14362 | 898-899 | CD | denotes | 5 |
| T14363 | 900-902 | NNP | denotes | mM |
| T14364 | 902-903 | -RRB- | denotes | ) |
| T14365 | 903-904 | , | denotes | , |
| T14366 | 905-907 | CC | denotes | or |
| T14367 | 908-912 | NNP | denotes | Poly |
| T14368 | 912-913 | -LRB- | denotes | ( |
| T14369 | 913-915 | NNP | denotes | dA |
| T14370 | 915-916 | : | denotes | : |
| T14371 | 916-918 | NN | denotes | dT |
| T14372 | 918-919 | -RRB- | denotes | ) |
| T14373 | 920-921 | -LRB- | denotes | ( |
| T14374 | 921-922 | CD | denotes | 1 |
| T14375 | 923-925 | NN | denotes | µg |
| T14376 | 925-926 | NN | denotes | / |
| T14377 | 926-928 | NN | denotes | ml |
| T14378 | 928-929 | -RRB- | denotes | ) |
| T14379 | 930-939 | VBG | denotes | according |
| T14380 | 940-942 | TO | denotes | to |
| T14381 | 943-946 | DT | denotes | the |
| T14382 | 947-955 | NN | denotes | schedule |
| T14383 | 956-958 | IN | denotes | in |
| T14384 | 959-965 | NN | denotes | Figure |
| T14385 | 966-967 | CD | denotes | 1 |
| T14386 | 967-968 | . | denotes | . |
| T14387 | 969-970 | -LRB- | denotes | ( |
| T14388 | 970-971 | NNP | denotes | G |
| T14389 | 971-972 | -RRB- | denotes | ) |
| T14390 | 973-978 | NN | denotes | IL-1β |
| T14391 | 979-982 | CC | denotes | and |
| T14392 | 983-984 | -LRB- | denotes | ( |
| T14393 | 984-985 | NNP | denotes | H |
| T14394 | 985-986 | -RRB- | denotes | ) |
| T14395 | 987-991 | NN | denotes | IL-8 |
| T14396 | 992-998 | NNS | denotes | levels |
| T14397 | 999-1003 | VBD | denotes | were |
| T14398 | 1004-1012 | VBN | denotes | measured |
| T14399 | 1013-1015 | IN | denotes | at |
| T14400 | 1016-1018 | CD | denotes | 24 |
| T14401 | 1019-1024 | NNS | denotes | hours |
| T14402 | 1024-1025 | . | denotes | . |
| T14403 | 1026-1037 | NNP | denotes | Statistical |
| T14404 | 1038-1046 | NN | denotes | analysis |
| T14405 | 1047-1050 | VBD | denotes | was |
| T14406 | 1051-1060 | VBN | denotes | performed |
| T14407 | 1061-1066 | VBG | denotes | using |
| T14408 | 1067-1070 | CD | denotes | two |
| T14409 | 1071-1074 | NN | denotes | way |
| T14410 | 1075-1080 | NNP | denotes | ANOVA |
| T14411 | 1081-1085 | IN | denotes | with |
| T14412 | 1086-1096 | NNP | denotes | Bonferroni |
| T14413 | 1097-1107 | NN | denotes | correction |
| T14414 | 1108-1111 | IN | denotes | for |
| T14415 | 1112-1120 | JJ | denotes | multiple |
| T14416 | 1121-1132 | NNS | denotes | comparisons |
| T14417 | 1132-1133 | . | denotes | . |
| T14418 | 1134-1135 | SYM | denotes | * |
| T14419 | 1135-1136 | , | denotes | , |
| T14420 | 1137-1139 | SYM | denotes | ** |
| T14421 | 1139-1140 | , | denotes | , |
| T14422 | 1141-1144 | CC | denotes | and |
| T14423 | 1145-1148 | RB | denotes | *** |
| T14424 | 1149-1156 | VB | denotes | signify |
| T14425 | 1157-1158 | NNP | denotes | P |
| T14426 | 1158-1159 | CD | denotes | < |
| T14427 | 1159-1163 | CD | denotes | 0.05 |
| T14428 | 1163-1164 | , | denotes | , |
| T14429 | 1165-1169 | CD | denotes | 0.01 |
| T14430 | 1169-1170 | , | denotes | , |
| T14431 | 1171-1174 | CC | denotes | and |
| T14432 | 1175-1180 | CD | denotes | 0.001 |
| T14433 | 1180-1181 | . | denotes | . |
| R12592 | T14178 | T14179 | amod | NF-κB,activation |
| R12593 | T14179 | T14180 | nsubj | activation,potentiates |
| R12594 | T14180 | T14180 | ROOT | potentiates,potentiates |
| R12595 | T14181 | T14182 | det | the,degree |
| R12596 | T14182 | T14180 | dobj | degree,potentiates |
| R12597 | T14183 | T14182 | prep | of,degree |
| R12598 | T14184 | T14185 | amod | IL-1β,production |
| R12599 | T14185 | T14183 | pobj | production,of |
| R12600 | T14186 | T14185 | cc | and,production |
| R12601 | T14187 | T14185 | conj | secretion,production |
| R12602 | T14188 | T14185 | prep | upon,production |
| R12603 | T14189 | T14190 | amod | inflammasome,activation |
| R12604 | T14190 | T14188 | pobj | activation,upon |
| R12605 | T14191 | T14180 | punct | .,potentiates |
| R12606 | T14192 | T14194 | nummod | THP-1,cells |
| R12607 | T14193 | T14194 | compound | reporter,cells |
| R12608 | T14194 | T14196 | nsubjpass | cells,primed |
| R12609 | T14195 | T14196 | auxpass | were,primed |
| R12610 | T14196 | T14196 | ROOT | primed,primed |
| R12611 | T14197 | T14196 | npadvmod | overnight,primed |
| R12612 | T14198 | T14197 | prep | with,overnight |
| R12613 | T14199 | T14201 | amod | heat-killed,aeruginosa |
| R12614 | T14200 | T14201 | compound | P.,aeruginosa |
| R12615 | T14201 | T14198 | pobj | aeruginosa,with |
| R12616 | T14202 | T14196 | cc | and,primed |
| R12617 | T14203 | T14196 | conj | stimulated,primed |
| R12618 | T14204 | T14206 | det | the,day |
| R12619 | T14205 | T14206 | amod | next,day |
| R12620 | T14206 | T14203 | dobj | day,stimulated |
| R12621 | T14207 | T14203 | prep | with,stimulated |
| R12622 | T14208 | T14210 | amod | live,aeruginosa |
| R12623 | T14209 | T14210 | compound | P.,aeruginosa |
| R12624 | T14210 | T14207 | pobj | aeruginosa,with |
| R12625 | T14211 | T14210 | cc | or,aeruginosa |
| R12626 | T14212 | T14215 | amod | additional,aeruginosa |
| R12627 | T14213 | T14215 | amod | heat-killed,aeruginosa |
| R12628 | T14214 | T14215 | compound | P.,aeruginosa |
| R12629 | T14215 | T14210 | conj | aeruginosa,aeruginosa |
| R12630 | T14216 | T14215 | prep | for,aeruginosa |
| R12631 | T14217 | T14218 | det | the,times |
| R12632 | T14218 | T14216 | pobj | times,for |
| R12633 | T14219 | T14203 | conj | indicated,stimulated |
| R12634 | T14220 | T14196 | punct | .,primed |
| R12635 | T14221 | T14223 | compound | Cell,supernatants |
| R12636 | T14222 | T14223 | compound | culture,supernatants |
| R12637 | T14223 | T14225 | nsubjpass | supernatants,assayed |
| R12638 | T14224 | T14225 | auxpass | were,assayed |
| R12639 | T14225 | T14225 | ROOT | assayed,assayed |
| R12640 | T14226 | T14225 | prep | for,assayed |
| R12641 | T14227 | T14228 | punct | (,A |
| R12642 | T14228 | T14233 | nmod | A,activity |
| R12643 | T14229 | T14228 | punct | ),A |
| R12644 | T14230 | T14233 | nmod | NF-κB,activity |
| R12645 | T14231 | T14233 | nmod | /,activity |
| R12646 | T14232 | T14233 | compound | AP-1,activity |
| R12647 | T14233 | T14226 | pobj | activity,for |
| R12648 | T14234 | T14233 | punct | ",",activity |
| R12649 | T14235 | T14238 | punct | (,IL-8 |
| R12650 | T14236 | T14238 | nmod | B,IL-8 |
| R12651 | T14237 | T14236 | punct | ),B |
| R12652 | T14238 | T14233 | appos | IL-8,activity |
| R12653 | T14239 | T14238 | punct | ",",IL-8 |
| R12654 | T14240 | T14238 | cc | and,IL-8 |
| R12655 | T14241 | T14242 | punct | (,C |
| R12656 | T14242 | T14245 | nmod | C,secretion |
| R12657 | T14243 | T14242 | punct | ),C |
| R12658 | T14244 | T14245 | amod | IL-1β,secretion |
| R12659 | T14245 | T14238 | conj | secretion,IL-8 |
| R12660 | T14246 | T14247 | punct | (,n |
| R12661 | T14247 | T14238 | conj | n,IL-8 |
| R12662 | T14248 | T14249 | punct | =,3 |
| R12663 | T14249 | T14247 | prep | 3,n |
| R12664 | T14250 | T14251 | nummod | 6,experiments |
| R12665 | T14251 | T14249 | appos | experiments,3 |
| R12701 | T14287 | T14286 | prep | at,assayed |
| R12666 | T14252 | T14249 | punct | ),3 |
| R12667 | T14253 | T14225 | punct | .,assayed |
| R12668 | T14254 | T14264 | advcl | Using,treated |
| R12669 | T14255 | T14258 | det | the,method |
| R12670 | T14256 | T14258 | amod | same,method |
| R12671 | T14257 | T14258 | compound | stimulation,method |
| R12672 | T14258 | T14254 | dobj | method,Using |
| R12673 | T14259 | T14264 | punct | ",",treated |
| R12674 | T14260 | T14262 | nummod | THP-1,cells |
| R12675 | T14261 | T14262 | compound | reporter,cells |
| R12676 | T14262 | T14264 | nsubjpass | cells,treated |
| R12677 | T14263 | T14264 | auxpass | were,treated |
| R12678 | T14264 | T14264 | ROOT | treated,treated |
| R12679 | T14265 | T14264 | prep | with,treated |
| R12680 | T14266 | T14265 | pobj | Bay11-7082,with |
| R12681 | T14267 | T14269 | punct | (,µM |
| R12682 | T14268 | T14269 | nummod | 20,µM |
| R12683 | T14269 | T14266 | appos | µM,Bay11-7082 |
| R12684 | T14270 | T14269 | punct | ),µM |
| R12685 | T14271 | T14264 | prep | for,treated |
| R12686 | T14272 | T14273 | nummod | 1,hour |
| R12687 | T14273 | T14271 | pobj | hour,for |
| R12688 | T14274 | T14264 | advmod | prior,treated |
| R12689 | T14275 | T14274 | prep | to,prior |
| R12690 | T14276 | T14275 | pobj | priming,to |
| R12691 | T14277 | T14276 | prep | with,priming |
| R12692 | T14278 | T14279 | compound | heat-killed,PAO1 |
| R12693 | T14279 | T14277 | pobj | PAO1,with |
| R12694 | T14280 | T14264 | cc | or,treated |
| R12695 | T14281 | T14264 | conj | live,treated |
| R12696 | T14282 | T14281 | npadvmod | PAO1,live |
| R12697 | T14283 | T14264 | punct | .,treated |
| R12698 | T14284 | T14286 | nsubjpass | Supernatants,assayed |
| R12699 | T14285 | T14286 | auxpass | were,assayed |
| R12700 | T14286 | T14286 | ROOT | assayed,assayed |
| R12702 | T14288 | T14289 | nummod | 24,hours |
| R12703 | T14289 | T14287 | pobj | hours,at |
| R12704 | T14290 | T14286 | prep | for,assayed |
| R12705 | T14291 | T14292 | punct | (,D |
| R12706 | T14292 | T14290 | pobj | D,for |
| R12707 | T14293 | T14292 | punct | ),D |
| R12708 | T14294 | T14296 | compound | NF-κB,AP-1 |
| R12709 | T14295 | T14296 | compound | /,AP-1 |
| R12710 | T14296 | T14297 | compound | AP-1,activity |
| R12711 | T14297 | T14297 | ROOT | activity,activity |
| R12712 | T14298 | T14297 | punct | ",",activity |
| R12713 | T14299 | T14302 | punct | (,IL-8 |
| R12714 | T14300 | T14302 | nmod | E,IL-8 |
| R12715 | T14301 | T14302 | punct | ),IL-8 |
| R12716 | T14302 | T14309 | nmod | IL-8,secretion |
| R12717 | T14303 | T14302 | punct | ",",IL-8 |
| R12718 | T14304 | T14302 | cc | and,IL-8 |
| R12719 | T14305 | T14306 | punct | (,F |
| R12720 | T14306 | T14302 | conj | F,IL-8 |
| R12721 | T14307 | T14306 | punct | ),F |
| R12722 | T14308 | T14309 | compound | IL-1β,secretion |
| R12723 | T14309 | T14297 | appos | secretion,activity |
| R12724 | T14310 | T14313 | punct | (,3 |
| R12725 | T14311 | T14313 | advmod | n,3 |
| R12726 | T14312 | T14313 | punct | =,3 |
| R12727 | T14313 | T14309 | nummod | 3,secretion |
| R12728 | T14314 | T14336 | meta | 5,treated |
| R12729 | T14315 | T14314 | punct | ),5 |
| R12730 | T14316 | T14314 | punct | .,5 |
| R12731 | T14317 | T14336 | nsubjpass | PBMCs,treated |
| R12732 | T14318 | T14317 | prep | from,PBMCs |
| R12733 | T14319 | T14320 | compound | CF,patients |
| R12734 | T14320 | T14318 | pobj | patients,from |
| R12735 | T14321 | T14320 | punct | (,patients |
| R12736 | T14322 | T14336 | nsubjpass | n,treated |
| R12737 | T14323 | T14324 | punct | =,11 |
| R12738 | T14324 | T14322 | prep | 11,n |
| R12739 | T14325 | T14324 | appos | 15,11 |
| R12740 | T14326 | T14324 | punct | ),11 |
| R12741 | T14327 | T14322 | cc | and,n |
| R12742 | T14328 | T14322 | conj | controls,n |
| R12743 | T14329 | T14332 | punct | (,10 |
| R12744 | T14330 | T14332 | advmod | n,10 |
| R12745 | T14331 | T14332 | punct | =,10 |
| R12746 | T14332 | T14322 | appos | 10,n |
| R12747 | T14333 | T14332 | appos | 13,10 |
| R12748 | T14334 | T14332 | punct | ),10 |
| R12749 | T14335 | T14336 | auxpass | were,treated |
| R12750 | T14336 | T14286 | advcl | treated,assayed |
| R12751 | T14337 | T14336 | prep | with,treated |
| R12752 | T14338 | T14337 | pobj | z-YVAD-fmk,with |
| R12753 | T14339 | T14341 | punct | (,µM |
| R12754 | T14340 | T14341 | nummod | 20,µM |
| R12755 | T14341 | T14338 | appos | µM,z-YVAD-fmk |
| R12756 | T14342 | T14341 | punct | ),µM |
| R12757 | T14343 | T14338 | cc | or,z-YVAD-fmk |
| R12758 | T14344 | T14338 | conj | Bay11-7082,z-YVAD-fmk |
| R12759 | T14345 | T14347 | punct | (,µM |
| R12760 | T14346 | T14347 | nummod | 10,µM |
| R12761 | T14347 | T14344 | appos | µM,Bay11-7082 |
| R12762 | T14348 | T14347 | punct | ),µM |
| R12763 | T14349 | T14336 | cc | and,treated |
| R12764 | T14350 | T14336 | conj | stimulated,treated |
| R12765 | T14351 | T14350 | prep | with,stimulated |
| R12766 | T14352 | T14353 | amod | live,PAO1 |
| R12767 | T14353 | T14351 | pobj | PAO1,with |
| R12768 | T14354 | T14377 | punct | (,ml |
| R12769 | T14355 | T14377 | nmod | MOI,ml |
| R12770 | T14356 | T14357 | punct | =,1 |
| R12771 | T14357 | T14355 | nummod | 1,MOI |
| R12772 | T14358 | T14357 | punct | ),1 |
| R12773 | T14359 | T14355 | punct | ",",MOI |
| R12774 | T14360 | T14355 | conj | ATP,MOI |
| R12775 | T14361 | T14362 | punct | (,5 |
| R12776 | T14362 | T14363 | nummod | 5,mM |
| R12777 | T14363 | T14355 | conj | mM,MOI |
| R12778 | T14364 | T14363 | punct | ),mM |
| R12779 | T14365 | T14355 | punct | ",",MOI |
| R12780 | T14366 | T14355 | cc | or,MOI |
| R12781 | T14367 | T14355 | conj | Poly,MOI |
| R12782 | T14368 | T14367 | punct | (,Poly |
| R12783 | T14369 | T14377 | nmod | dA,ml |
| R12784 | T14370 | T14369 | punct | :,dA |
| R12785 | T14371 | T14369 | appos | dT,dA |
| R12786 | T14372 | T14369 | punct | ),dA |
| R12787 | T14373 | T14377 | punct | (,ml |
| R12788 | T14374 | T14375 | nummod | 1,µg |
| R12789 | T14375 | T14377 | nmod | µg,ml |
| R12790 | T14376 | T14377 | compound | /,ml |
| R12791 | T14377 | T14353 | appos | ml,PAO1 |
| R12792 | T14378 | T14377 | punct | ),ml |
| R12793 | T14379 | T14286 | prep | according,assayed |
| R12794 | T14380 | T14379 | prep | to,according |
| R12795 | T14381 | T14382 | det | the,schedule |
| R12796 | T14382 | T14380 | pobj | schedule,to |
| R12797 | T14383 | T14382 | prep | in,schedule |
| R12798 | T14384 | T14383 | pobj | Figure,in |
| R12799 | T14385 | T14384 | nummod | 1,Figure |
| R12800 | T14386 | T14286 | punct | .,assayed |
| R12801 | T14387 | T14390 | punct | (,IL-1β |
| R12802 | T14388 | T14390 | nmod | G,IL-1β |
| R12803 | T14389 | T14390 | punct | ),IL-1β |
| R12804 | T14390 | T14396 | nmod | IL-1β,levels |
| R12805 | T14391 | T14390 | cc | and,IL-1β |
| R12806 | T14392 | T14393 | punct | (,H |
| R12807 | T14393 | T14390 | conj | H,IL-1β |
| R12808 | T14394 | T14393 | punct | ),H |
| R12809 | T14395 | T14396 | compound | IL-8,levels |
| R12810 | T14396 | T14398 | nsubjpass | levels,measured |
| R12811 | T14397 | T14398 | auxpass | were,measured |
| R12812 | T14398 | T14398 | ROOT | measured,measured |
| R12813 | T14399 | T14398 | prep | at,measured |
| R12814 | T14400 | T14401 | nummod | 24,hours |
| R12815 | T14401 | T14399 | pobj | hours,at |
| R12816 | T14402 | T14398 | punct | .,measured |
| R12817 | T14403 | T14404 | compound | Statistical,analysis |
| R12818 | T14404 | T14406 | nsubjpass | analysis,performed |
| R12819 | T14405 | T14406 | auxpass | was,performed |
| R12820 | T14406 | T14406 | ROOT | performed,performed |
| R12821 | T14407 | T14406 | advcl | using,performed |
| R12822 | T14408 | T14409 | nummod | two,way |
| R12823 | T14409 | T14410 | advmod | way,ANOVA |
| R12824 | T14410 | T14407 | dobj | ANOVA,using |
| R12825 | T14411 | T14410 | prep | with,ANOVA |
| R12826 | T14412 | T14413 | compound | Bonferroni,correction |
| R12827 | T14413 | T14411 | pobj | correction,with |
| R12828 | T14414 | T14413 | prep | for,correction |
| R12829 | T14415 | T14416 | amod | multiple,comparisons |
| R12830 | T14416 | T14414 | pobj | comparisons,for |
| R12831 | T14417 | T14406 | punct | .,performed |
| R12832 | T14418 | T14424 | punct | *,signify |
| R12833 | T14419 | T14424 | punct | ",",signify |
| R12834 | T14420 | T14424 | nsubj | **,signify |
| R12835 | T14421 | T14420 | punct | ",",** |
| R12836 | T14422 | T14420 | cc | and,** |
| R12837 | T14423 | T14424 | advmod | ***,signify |
| R12838 | T14424 | T14424 | ROOT | signify,signify |
| R12839 | T14425 | T14424 | dobj | P,signify |
| R12840 | T14426 | T14425 | nummod | <,P |
| R12841 | T14427 | T14425 | nummod | 0.05,P |
| R12842 | T14428 | T14425 | punct | ",",P |
| R12843 | T14429 | T14425 | appos | 0.01,P |
| R12844 | T14430 | T14425 | punct | ",",P |
| R12845 | T14431 | T14425 | cc | and,P |
| R12846 | T14432 | T14425 | conj | 0.001,P |
| R12847 | T14433 | T14424 | punct | .,signify |
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T13942 | 44-49 | NN | denotes | NF-κB |
| T13943 | 50-60 | NN | denotes | activation |
| T13944 | 61-72 | VB | denotes | potentiates |
| T13945 | 73-76 | DT | denotes | the |
| T13946 | 77-83 | NN | denotes | degree |
| T13947 | 84-86 | IN | denotes | of |
| T13948 | 87-92 | NN | denotes | IL-1β |
| T13949 | 93-103 | NN | denotes | production |
| T13950 | 104-107 | CC | denotes | and |
| T13951 | 108-117 | NN | denotes | secretion |
| T13952 | 118-122 | IN | denotes | upon |
| T13953 | 123-135 | JJ | denotes | inflammasome |
| T13954 | 136-146 | NN | denotes | activation |
| T13955 | 148-153 | NN | denotes | THP-1 |
| T13956 | 154-162 | NN | denotes | reporter |
| T13957 | 163-168 | NN | denotes | cells |
| T13958 | 169-173 | VB | denotes | were |
| T13959 | 174-180 | VB | denotes | primed |
| T13960 | 181-190 | RB | denotes | overnight |
| T13961 | 191-195 | IN | denotes | with |
| T13962 | 196-207 | JJ | denotes | heat-killed |
| T13963 | 208-210 | NNP | denotes | P. |
| T13964 | 211-221 | NN | denotes | aeruginosa |
| T13965 | 222-225 | CC | denotes | and |
| T13966 | 226-236 | VB | denotes | stimulated |
| T13967 | 237-240 | DT | denotes | the |
| T13968 | 241-245 | JJ | denotes | next |
| T13969 | 246-249 | NN | denotes | day |
| T13970 | 250-254 | IN | denotes | with |
| T13971 | 255-259 | JJ | denotes | live |
| T13972 | 260-262 | NNP | denotes | P. |
| T13973 | 263-273 | NN | denotes | aeruginosa |
| T13974 | 274-276 | CC | denotes | or |
| T13975 | 277-287 | JJ | denotes | additional |
| T13976 | 288-299 | JJ | denotes | heat-killed |
| T13977 | 300-302 | NNP | denotes | P. |
| T13978 | 303-313 | NN | denotes | aeruginosa |
| T13979 | 314-317 | IN | denotes | for |
| T13980 | 318-321 | DT | denotes | the |
| T13981 | 322-327 | NN | denotes | times |
| T13982 | 328-337 | VB | denotes | indicated |
| T13983 | 339-343 | NN | denotes | Cell |
| T13984 | 344-351 | NN | denotes | culture |
| T13985 | 352-364 | NN | denotes | supernatants |
| T13986 | 365-369 | VB | denotes | were |
| T13987 | 370-377 | VB | denotes | assayed |
| T13988 | 378-381 | IN | denotes | for |
| T13989 | 382-383 | -LRB- | denotes | ( |
| T13990 | 383-384 | NN | denotes | A |
| T13991 | 384-385 | -RRB- | denotes | ) |
| T13992 | 386-396 | NN | denotes | NF-κB/AP-1 |
| T13993 | 397-405 | NN | denotes | activity |
| T13994 | 405-406 | -COMMA- | denotes | , |
| T13995 | 407-408 | -LRB- | denotes | ( |
| T13996 | 408-409 | NN | denotes | B |
| T13997 | 409-410 | -RRB- | denotes | ) |
| T13998 | 411-415 | NN | denotes | IL-8 |
| T13999 | 415-416 | -COMMA- | denotes | , |
| T14000 | 417-420 | CC | denotes | and |
| T14001 | 421-422 | -LRB- | denotes | ( |
| T14002 | 422-423 | NN | denotes | C |
| T14003 | 423-424 | -RRB- | denotes | ) |
| T14004 | 425-430 | NN | denotes | IL-1β |
| T14005 | 431-440 | NN | denotes | secretion |
| T14006 | 441-442 | -LRB- | denotes | ( |
| T14007 | 442-449 | NN | denotes | n = 3–6 |
| T14008 | 450-461 | NN | denotes | experiments |
| T14009 | 461-462 | -RRB- | denotes | ) |
| T14010 | 464-469 | VB | denotes | Using |
| T14011 | 470-473 | DT | denotes | the |
| T14012 | 474-478 | JJ | denotes | same |
| T14013 | 479-490 | NN | denotes | stimulation |
| T14014 | 491-497 | NN | denotes | method |
| T14015 | 497-498 | -COMMA- | denotes | , |
| T14016 | 499-504 | NN | denotes | THP-1 |
| T14017 | 505-513 | NN | denotes | reporter |
| T14018 | 514-519 | NN | denotes | cells |
| T14019 | 520-524 | VB | denotes | were |
| T14020 | 525-532 | VB | denotes | treated |
| T14021 | 533-537 | IN | denotes | with |
| T14022 | 538-548 | NN | denotes | Bay11-7082 |
| T14023 | 549-550 | -LRB- | denotes | ( |
| T14024 | 550-552 | CD | denotes | 20 |
| T14025 | 553-555 | NN | denotes | µM |
| T14026 | 555-556 | -RRB- | denotes | ) |
| T14027 | 557-560 | IN | denotes | for |
| T14028 | 561-562 | CD | denotes | 1 |
| T14029 | 563-567 | NN | denotes | hour |
| T14030 | 568-573 | JJ | denotes | prior |
| T14031 | 574-576 | TO | denotes | to |
| T14032 | 577-584 | NN | denotes | priming |
| T14033 | 585-589 | IN | denotes | with |
| T14034 | 590-601 | JJ | denotes | heat-killed |
| T14035 | 602-606 | NN | denotes | PAO1 |
| T14036 | 607-609 | CC | denotes | or |
| T14037 | 610-614 | JJ | denotes | live |
| T14038 | 615-619 | NN | denotes | PAO1 |
| T14039 | 621-633 | NN | denotes | Supernatants |
| T14040 | 634-638 | VB | denotes | were |
| T14041 | 639-646 | VB | denotes | assayed |
| T14042 | 647-649 | IN | denotes | at |
| T14043 | 650-652 | CD | denotes | 24 |
| T14044 | 653-658 | NN | denotes | hours |
| T14045 | 659-662 | IN | denotes | for |
| T14046 | 663-664 | -LRB- | denotes | ( |
| T14047 | 664-665 | NN | denotes | D |
| T14048 | 665-666 | -RRB- | denotes | ) |
| T14049 | 667-677 | NN | denotes | NF-κB/AP-1 |
| T14050 | 678-686 | NN | denotes | activity |
| T14051 | 686-687 | -COMMA- | denotes | , |
| T14052 | 688-689 | -LRB- | denotes | ( |
| T14053 | 689-690 | NN | denotes | E |
| T14054 | 690-691 | -RRB- | denotes | ) |
| T14055 | 692-696 | NN | denotes | IL-8 |
| T14056 | 696-697 | -COMMA- | denotes | , |
| T14057 | 698-701 | CC | denotes | and |
| T14058 | 702-703 | -LRB- | denotes | ( |
| T14059 | 703-704 | NN | denotes | F |
| T14060 | 704-705 | -RRB- | denotes | ) |
| T14061 | 706-711 | NN | denotes | IL-1β |
| T14062 | 712-721 | NN | denotes | secretion |
| T14063 | 722-723 | -LRB- | denotes | ( |
| T14064 | 723-730 | NN | denotes | n = 3–5 |
| T14065 | 730-731 | -RRB- | denotes | ) |
| T14066 | 733-738 | NN | denotes | PBMCs |
| T14067 | 739-743 | IN | denotes | from |
| T14068 | 744-746 | NN | denotes | CF |
| T14069 | 747-755 | NN | denotes | patients |
| T14070 | 756-757 | -LRB- | denotes | ( |
| T14071 | 757-766 | NN | denotes | n = 11–15 |
| T14072 | 766-767 | -RRB- | denotes | ) |
| T14073 | 768-771 | CC | denotes | and |
| T14074 | 772-780 | NN | denotes | controls |
| T14075 | 781-782 | -LRB- | denotes | ( |
| T14076 | 782-791 | NN | denotes | n = 10–13 |
| T14077 | 791-792 | -RRB- | denotes | ) |
| T14078 | 793-797 | VB | denotes | were |
| T14079 | 798-805 | VB | denotes | treated |
| T14080 | 806-810 | IN | denotes | with |
| T14081 | 811-821 | NN | denotes | z-YVAD-fmk |
| T14082 | 822-823 | -LRB- | denotes | ( |
| T14083 | 823-825 | CD | denotes | 20 |
| T14084 | 826-828 | NN | denotes | µM |
| T14085 | 828-829 | -RRB- | denotes | ) |
| T14086 | 830-832 | CC | denotes | or |
| T14087 | 833-843 | NN | denotes | Bay11-7082 |
| T14088 | 844-845 | -LRB- | denotes | ( |
| T14089 | 845-847 | CD | denotes | 10 |
| T14090 | 848-850 | NN | denotes | µM |
| T14091 | 850-851 | -RRB- | denotes | ) |
| T14092 | 852-855 | CC | denotes | and |
| T14093 | 856-866 | VB | denotes | stimulated |
| T14094 | 867-871 | IN | denotes | with |
| T14095 | 872-876 | JJ | denotes | live |
| T14096 | 877-881 | NN | denotes | PAO1 |
| T14097 | 882-883 | -LRB- | denotes | ( |
| T14098 | 883-890 | NN | denotes | MOI = 1 |
| T14099 | 890-891 | -RRB- | denotes | ) |
| T14100 | 891-892 | -COMMA- | denotes | , |
| T14101 | 893-896 | NN | denotes | ATP |
| T14102 | 897-898 | -LRB- | denotes | ( |
| T14103 | 898-899 | CD | denotes | 5 |
| T14104 | 900-902 | NN | denotes | mM |
| T14105 | 902-903 | -RRB- | denotes | ) |
| T14106 | 903-904 | -COMMA- | denotes | , |
| T14107 | 905-907 | CC | denotes | or |
| T14108 | 908-912 | NNP | denotes | Poly |
| T14109 | 912-913 | -LRB- | denotes | ( |
| T14110 | 913-915 | NN | denotes | dA |
| T14111 | 915-916 | -COLON- | denotes | : |
| T14112 | 916-918 | NN | denotes | dT |
| T14113 | 918-919 | -RRB- | denotes | ) |
| T14114 | 920-921 | -LRB- | denotes | ( |
| T14115 | 921-922 | CD | denotes | 1 |
| T14116 | 923-928 | NN | denotes | µg/ml |
| T14117 | 928-929 | -RRB- | denotes | ) |
| T14118 | 930-939 | VB | denotes | according |
| T14119 | 940-942 | TO | denotes | to |
| T14120 | 943-946 | DT | denotes | the |
| T14121 | 947-955 | NN | denotes | schedule |
| T14122 | 956-958 | IN | denotes | in |
| T14123 | 959-965 | NN | denotes | Figure |
| T14124 | 966-968 | CD | denotes | 1. |
| T14125 | 969-970 | -LRB- | denotes | ( |
| T14126 | 970-971 | NN | denotes | G |
| T14127 | 971-972 | -RRB- | denotes | ) |
| T14128 | 973-978 | NN | denotes | IL-1β |
| T14129 | 979-982 | CC | denotes | and |
| T14130 | 983-984 | -LRB- | denotes | ( |
| T14131 | 984-985 | NN | denotes | H |
| T14132 | 985-986 | -RRB- | denotes | ) |
| T14133 | 987-991 | NN | denotes | IL-8 |
| T14134 | 992-998 | NN | denotes | levels |
| T14135 | 999-1003 | VB | denotes | were |
| T14136 | 1004-1012 | VB | denotes | measured |
| T14137 | 1013-1015 | IN | denotes | at |
| T14138 | 1016-1018 | CD | denotes | 24 |
| T14139 | 1019-1024 | NN | denotes | hours |
| T14140 | 1026-1037 | JJ | denotes | Statistical |
| T14141 | 1038-1046 | NN | denotes | analysis |
| T14142 | 1047-1050 | VB | denotes | was |
| T14143 | 1051-1060 | VB | denotes | performed |
| T14144 | 1061-1066 | VB | denotes | using |
| T14145 | 1067-1070 | CD | denotes | two |
| T14146 | 1071-1074 | NN | denotes | way |
| T14147 | 1075-1080 | NN | denotes | ANOVA |
| T14148 | 1081-1085 | IN | denotes | with |
| T14149 | 1086-1096 | NNP | denotes | Bonferroni |
| T14150 | 1097-1107 | NN | denotes | correction |
| T14151 | 1108-1111 | IN | denotes | for |
| T14152 | 1112-1120 | JJ | denotes | multiple |
| T14153 | 1121-1133 | NN | denotes | comparisons. |
| T14154 | 1134-1135 | SYM | denotes | * |
| T14155 | 1135-1136 | -COMMA- | denotes | , |
| T14156 | 1137-1139 | SYM | denotes | ** |
| T14157 | 1139-1140 | -COMMA- | denotes | , |
| T14158 | 1141-1144 | CC | denotes | and |
| T14159 | 1145-1148 | SYM | denotes | *** |
| T14160 | 1149-1156 | VB | denotes | signify |
| T14161 | 1157-1158 | NN | denotes | P |
| T14162 | 1158-1159 | SYM | denotes | < |
| T14163 | 1159-1163 | CD | denotes | 0.05 |
| T14164 | 1163-1164 | -COMMA- | denotes | , |
| T14165 | 1165-1169 | CD | denotes | 0.01 |
| T14166 | 1169-1170 | -COMMA- | denotes | , |
| T14167 | 1171-1174 | CC | denotes | and |
| T14168 | 1175-1180 | CD | denotes | 0.001 |
| R12360 | T13943 | T13942 | arg1Of | activation,NF-κB |
| R12361 | T13943 | T13944 | arg1Of | activation,potentiates |
| R12362 | T13946 | T13944 | arg2Of | degree,potentiates |
| R12363 | T13946 | T13945 | arg1Of | degree,the |
| R12364 | T13946 | T13947 | arg1Of | degree,of |
| R12365 | T13946 | T13952 | arg1Of | degree,upon |
| R12366 | T13949 | T13950 | arg1Of | production,and |
| R12367 | T13950 | T13947 | arg2Of | and,of |
| R12368 | T13950 | T13948 | arg1Of | and,IL-1β |
| R12369 | T13951 | T13950 | arg2Of | secretion,and |
| R12370 | T13954 | T13952 | arg2Of | activation,upon |
| R12371 | T13954 | T13953 | arg1Of | activation,inflammasome |
| R12372 | T13957 | T13955 | arg1Of | cells,THP-1 |
| R12373 | T13957 | T13956 | arg1Of | cells,reporter |
| R12374 | T13957 | T13958 | arg1Of | cells,were |
| R12375 | T13957 | T13959 | arg2Of | cells,primed |
| R12376 | T13957 | T13966 | arg1Of | cells,stimulated |
| R12377 | T13959 | T13958 | arg2Of | primed,were |
| R12378 | T13959 | T13960 | arg1Of | primed,overnight |
| R12379 | T13959 | T13961 | arg1Of | primed,with |
| R12380 | T13959 | T13965 | arg1Of | primed,and |
| R12381 | T13964 | T13961 | arg2Of | aeruginosa,with |
| R12382 | T13964 | T13962 | arg1Of | aeruginosa,heat-killed |
| R12383 | T13964 | T13963 | arg1Of | aeruginosa,P. |
| R12384 | T13965 | T13982 | arg2Of | and,indicated |
| R12385 | T13966 | T13965 | arg2Of | stimulated,and |
| R12386 | T13966 | T13970 | arg1Of | stimulated,with |
| R12387 | T13969 | T13966 | arg2Of | day,stimulated |
| R12388 | T13969 | T13967 | arg1Of | day,the |
| R12389 | T13969 | T13968 | arg1Of | day,next |
| R12390 | T13973 | T13970 | arg2Of | aeruginosa,with |
| R12391 | T13973 | T13971 | arg1Of | aeruginosa,live |
| R12392 | T13973 | T13972 | arg1Of | aeruginosa,P. |
| R12393 | T13978 | T13974 | arg1Of | aeruginosa,or |
| R12394 | T13978 | T13975 | arg1Of | aeruginosa,additional |
| R12395 | T13978 | T13976 | arg1Of | aeruginosa,heat-killed |
| R12396 | T13978 | T13977 | arg1Of | aeruginosa,P. |
| R12397 | T13978 | T13979 | arg1Of | aeruginosa,for |
| R12398 | T13978 | T13982 | arg1Of | aeruginosa,indicated |
| R12399 | T13981 | T13979 | arg2Of | times,for |
| R12400 | T13981 | T13980 | arg1Of | times,the |
| R12401 | T13985 | T13983 | arg1Of | supernatants,Cell |
| R12402 | T13985 | T13984 | arg1Of | supernatants,culture |
| R12403 | T13985 | T13986 | arg1Of | supernatants,were |
| R12404 | T13985 | T13987 | arg2Of | supernatants,assayed |
| R12405 | T13987 | T13986 | arg2Of | assayed,were |
| R12406 | T13987 | T13988 | arg1Of | assayed,for |
| R12407 | T13990 | T13989 | arg2Of | A,( |
| R12408 | T13991 | T13989 | arg3Of | ),( |
| R12409 | T13993 | T13989 | arg1Of | activity,( |
| R12410 | T13993 | T13992 | arg1Of | activity,NF-κB/AP-1 |
| R12411 | T13993 | T13994 | arg1Of | activity,"," |
| R12412 | T13994 | T14000 | arg1Of | ",",and |
| R12413 | T13996 | T13995 | arg2Of | B,( |
| R12414 | T13997 | T13995 | arg3Of | ),( |
| R12415 | T13998 | T13994 | arg2Of | IL-8,"," |
| R12416 | T13998 | T13995 | arg1Of | IL-8,( |
| R12417 | T14000 | T13988 | arg2Of | and,for |
| R12418 | T14000 | T13999 | arg1Of | and,"," |
| R12419 | T14002 | T14001 | arg2Of | C,( |
| R12420 | T14003 | T14001 | arg3Of | ),( |
| R12421 | T14005 | T14000 | arg2Of | secretion,and |
| R12422 | T14005 | T14001 | arg1Of | secretion,( |
| R12423 | T14005 | T14004 | arg1Of | secretion,IL-1β |
| R12424 | T14005 | T14006 | arg1Of | secretion,( |
| R12425 | T14008 | T14006 | arg2Of | experiments,( |
| R12426 | T14008 | T14007 | arg1Of | experiments,n = 3–6 |
| R12427 | T14009 | T14006 | arg3Of | ),( |
| R12428 | T14014 | T14010 | arg2Of | method,Using |
| R12429 | T14014 | T14011 | arg1Of | method,the |
| R12430 | T14014 | T14012 | arg1Of | method,same |
| R12431 | T14014 | T14013 | arg1Of | method,stimulation |
| R12432 | T14018 | T14016 | arg1Of | cells,THP-1 |
| R12433 | T14018 | T14017 | arg1Of | cells,reporter |
| R12434 | T14018 | T14019 | arg1Of | cells,were |
| R12435 | T14018 | T14020 | arg2Of | cells,treated |
| R12436 | T14020 | T14010 | modOf | treated,Using |
| R12437 | T14020 | T14015 | arg1Of | treated,"," |
| R12438 | T14020 | T14019 | arg2Of | treated,were |
| R12439 | T14020 | T14021 | arg1Of | treated,with |
| R12440 | T14020 | T14027 | arg1Of | treated,for |
| R12441 | T14022 | T14021 | arg2Of | Bay11-7082,with |
| R12442 | T14022 | T14023 | arg1Of | Bay11-7082,( |
| R12443 | T14025 | T14023 | arg2Of | µM,( |
| R12444 | T14025 | T14024 | arg1Of | µM,20 |
| R12445 | T14026 | T14023 | arg3Of | ),( |
| R12446 | T14029 | T14027 | arg2Of | hour,for |
| R12447 | T14029 | T14028 | arg1Of | hour,1 |
| R12448 | T14029 | T14030 | arg1Of | hour,prior |
| R12449 | T14030 | T14031 | arg1Of | prior,to |
| R12450 | T14032 | T14031 | arg2Of | priming,to |
| R12451 | T14032 | T14033 | arg1Of | priming,with |
| R12452 | T14035 | T14034 | arg1Of | PAO1,heat-killed |
| R12453 | T14035 | T14036 | arg1Of | PAO1,or |
| R12454 | T14036 | T14033 | arg2Of | or,with |
| R12455 | T14038 | T14036 | arg2Of | PAO1,or |
| R12456 | T14038 | T14037 | arg1Of | PAO1,live |
| R12457 | T14039 | T14040 | arg1Of | Supernatants,were |
| R12458 | T14039 | T14041 | arg2Of | Supernatants,assayed |
| R12459 | T14041 | T14040 | arg2Of | assayed,were |
| R12460 | T14041 | T14042 | arg1Of | assayed,at |
| R12461 | T14041 | T14045 | arg1Of | assayed,for |
| R12462 | T14044 | T14042 | arg2Of | hours,at |
| R12463 | T14044 | T14043 | arg1Of | hours,24 |
| R12464 | T14047 | T14046 | arg2Of | D,( |
| R12465 | T14048 | T14046 | arg3Of | ),( |
| R12466 | T14050 | T14046 | arg1Of | activity,( |
| R12467 | T14050 | T14049 | arg1Of | activity,NF-κB/AP-1 |
| R12468 | T14050 | T14051 | arg1Of | activity,"," |
| R12469 | T14051 | T14057 | arg1Of | ",",and |
| R12470 | T14053 | T14052 | arg2Of | E,( |
| R12471 | T14054 | T14052 | arg3Of | ),( |
| R12472 | T14055 | T14051 | arg2Of | IL-8,"," |
| R12473 | T14055 | T14052 | arg1Of | IL-8,( |
| R12474 | T14057 | T14045 | arg2Of | and,for |
| R12475 | T14057 | T14056 | arg1Of | and,"," |
| R12476 | T14059 | T14058 | arg2Of | F,( |
| R12477 | T14060 | T14058 | arg3Of | ),( |
| R12478 | T14062 | T14057 | arg2Of | secretion,and |
| R12479 | T14062 | T14058 | arg1Of | secretion,( |
| R12480 | T14062 | T14061 | arg1Of | secretion,IL-1β |
| R12481 | T14062 | T14063 | arg1Of | secretion,( |
| R12482 | T14064 | T14063 | arg2Of | n = 3–5,( |
| R12483 | T14065 | T14063 | arg3Of | ),( |
| R12484 | T14066 | T14067 | arg1Of | PBMCs,from |
| R12485 | T14066 | T14078 | arg1Of | PBMCs,were |
| R12486 | T14066 | T14079 | arg2Of | PBMCs,treated |
| R12487 | T14066 | T14093 | arg2Of | PBMCs,stimulated |
| R12488 | T14069 | T14068 | arg1Of | patients,CF |
| R12489 | T14069 | T14070 | arg1Of | patients,( |
| R12490 | T14069 | T14073 | arg1Of | patients,and |
| R12491 | T14071 | T14070 | arg2Of | n = 11–15,( |
| R12492 | T14072 | T14070 | arg3Of | ),( |
| R12493 | T14073 | T14067 | arg2Of | and,from |
| R12494 | T14074 | T14073 | arg2Of | controls,and |
| R12495 | T14074 | T14075 | arg1Of | controls,( |
| R12496 | T14076 | T14075 | arg2Of | n = 10–13,( |
| R12497 | T14077 | T14075 | arg3Of | ),( |
| R12498 | T14079 | T14080 | arg1Of | treated,with |
| R12499 | T14079 | T14092 | arg1Of | treated,and |
| R12500 | T14081 | T14082 | arg1Of | z-YVAD-fmk,( |
| R12501 | T14081 | T14086 | arg1Of | z-YVAD-fmk,or |
| R12502 | T14084 | T14082 | arg2Of | µM,( |
| R12503 | T14084 | T14083 | arg1Of | µM,20 |
| R12504 | T14085 | T14082 | arg3Of | ),( |
| R12505 | T14086 | T14080 | arg2Of | or,with |
| R12506 | T14087 | T14086 | arg2Of | Bay11-7082,or |
| R12507 | T14087 | T14088 | arg1Of | Bay11-7082,( |
| R12508 | T14090 | T14088 | arg2Of | µM,( |
| R12509 | T14090 | T14089 | arg1Of | µM,10 |
| R12510 | T14091 | T14088 | arg3Of | ),( |
| R12511 | T14092 | T14078 | arg2Of | and,were |
| R12512 | T14092 | T14118 | arg1Of | and,according |
| R12513 | T14092 | T14129 | arg1Of | and,and |
| R12514 | T14093 | T14092 | arg2Of | stimulated,and |
| R12515 | T14093 | T14094 | arg1Of | stimulated,with |
| R12516 | T14096 | T14095 | arg1Of | PAO1,live |
| R12517 | T14096 | T14097 | arg1Of | PAO1,( |
| R12518 | T14096 | T14100 | arg1Of | PAO1,"," |
| R12519 | T14098 | T14097 | arg2Of | MOI = 1,( |
| R12520 | T14099 | T14097 | arg3Of | ),( |
| R12521 | T14100 | T14107 | arg1Of | ",",or |
| R12522 | T14101 | T14100 | arg2Of | ATP,"," |
| R12523 | T14101 | T14102 | arg1Of | ATP,( |
| R12524 | T14104 | T14102 | arg2Of | mM,( |
| R12525 | T14104 | T14103 | arg1Of | mM,5 |
| R12526 | T14105 | T14102 | arg3Of | ),( |
| R12527 | T14107 | T14094 | arg2Of | or,with |
| R12528 | T14107 | T14106 | arg1Of | or,"," |
| R12529 | T14108 | T14107 | arg2Of | Poly,or |
| R12530 | T14108 | T14109 | arg1Of | Poly,( |
| R12531 | T14108 | T14114 | arg1Of | Poly,( |
| R12532 | T14110 | T14109 | arg2Of | dA,( |
| R12533 | T14110 | T14111 | arg1Of | dA,: |
| R12534 | T14110 | T14112 | arg1Of | dA,dT |
| R12535 | T14113 | T14109 | arg3Of | ),( |
| R12536 | T14116 | T14114 | arg2Of | µg/ml,( |
| R12537 | T14116 | T14115 | arg1Of | µg/ml,1 |
| R12538 | T14117 | T14114 | arg3Of | ),( |
| R12539 | T14119 | T14118 | arg2Of | to,according |
| R12540 | T14121 | T14119 | arg2Of | schedule,to |
| R12541 | T14121 | T14120 | arg1Of | schedule,the |
| R12542 | T14121 | T14122 | arg1Of | schedule,in |
| R12543 | T14123 | T14124 | arg1Of | Figure,1. |
| R12544 | T14123 | T14125 | arg1Of | Figure,( |
| R12545 | T14126 | T14125 | arg2Of | G,( |
| R12546 | T14127 | T14125 | arg3Of | ),( |
| R12547 | T14128 | T14122 | arg2Of | IL-1β,in |
| R12548 | T14128 | T14123 | arg1Of | IL-1β,Figure |
| R12549 | T14131 | T14130 | arg2Of | H,( |
| R12550 | T14132 | T14130 | arg3Of | ),( |
| R12551 | T14134 | T14130 | arg1Of | levels,( |
| R12552 | T14134 | T14133 | arg1Of | levels,IL-8 |
| R12553 | T14134 | T14135 | arg1Of | levels,were |
| R12554 | T14134 | T14136 | arg2Of | levels,measured |
| R12555 | T14136 | T14129 | arg2Of | measured,and |
| R12556 | T14136 | T14135 | arg2Of | measured,were |
| R12557 | T14136 | T14137 | arg1Of | measured,at |
| R12558 | T14139 | T14137 | arg2Of | hours,at |
| R12559 | T14139 | T14138 | arg1Of | hours,24 |
| R12560 | T14141 | T14140 | arg1Of | analysis,Statistical |
| R12561 | T14141 | T14142 | arg1Of | analysis,was |
| R12562 | T14141 | T14143 | arg2Of | analysis,performed |
| R12563 | T14143 | T14142 | arg2Of | performed,was |
| R12564 | T14143 | T14158 | arg1Of | performed,and |
| R12565 | T14144 | T14143 | arg3Of | using,performed |
| R12566 | T14147 | T14144 | arg2Of | ANOVA,using |
| R12567 | T14147 | T14145 | arg1Of | ANOVA,two |
| R12568 | T14147 | T14146 | arg1Of | ANOVA,way |
| R12569 | T14147 | T14148 | arg1Of | ANOVA,with |
| R12570 | T14147 | T14151 | arg1Of | ANOVA,for |
| R12571 | T14147 | T14154 | arg1Of | ANOVA,* |
| R12572 | T14147 | T14156 | arg1Of | ANOVA,** |
| R12573 | T14150 | T14148 | arg2Of | correction,with |
| R12574 | T14150 | T14149 | arg1Of | correction,Bonferroni |
| R12575 | T14153 | T14151 | arg2Of | comparisons.,for |
| R12576 | T14153 | T14152 | arg1Of | comparisons.,multiple |
| R12577 | T14154 | T14155 | arg1Of | *,"," |
| R12578 | T14156 | T14155 | arg2Of | **,"," |
| R12579 | T14158 | T14157 | arg1Of | and,"," |
| R12580 | T14158 | T14163 | arg1Of | and,0.05 |
| R12581 | T14158 | T14165 | arg1Of | and,0.01 |
| R12582 | T14158 | T14168 | arg1Of | and,0.001 |
| R12583 | T14159 | T14160 | arg1Of | ***,signify |
| R12584 | T14160 | T14158 | arg2Of | signify,and |
| R12585 | T14161 | T14160 | arg2Of | P,signify |
| R12586 | T14161 | T14162 | arg1Of | P,< |
| R12587 | T14163 | T14164 | arg1Of | 0.05,"," |
| R12588 | T14164 | T14167 | arg1Of | ",",and |
| R12589 | T14165 | T14164 | arg2Of | 0.01,"," |
| R12590 | T14167 | T14166 | arg1Of | and,"," |
| R12591 | T14168 | T14167 | arg2Of | 0.001,and |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T13935 | 44-147 | Sentence | denotes | NF-κB activation potentiates the degree of IL-1β production and secretion upon inflammasome activation. |
| T13936 | 148-338 | Sentence | denotes | THP-1 reporter cells were primed overnight with heat-killed P. aeruginosa and stimulated the next day with live P. aeruginosa or additional heat-killed P. aeruginosa for the times indicated. |
| T13937 | 339-463 | Sentence | denotes | Cell culture supernatants were assayed for (A) NF-κB/AP-1 activity, (B) IL-8, and (C) IL-1β secretion (n = 3–6 experiments). |
| T13938 | 464-620 | Sentence | denotes | Using the same stimulation method, THP-1 reporter cells were treated with Bay11-7082 (20 µM) for 1 hour prior to priming with heat-killed PAO1 or live PAO1. |
| T13939 | 621-732 | Sentence | denotes | Supernatants were assayed at 24 hours for (D) NF-κB/AP-1 activity, (E) IL-8, and (F) IL-1β secretion (n = 3–5). |
| T13940 | 733-1025 | Sentence | denotes | PBMCs from CF patients (n = 11–15) and controls (n = 10–13) were treated with z-YVAD-fmk (20 µM) or Bay11-7082 (10 µM) and stimulated with live PAO1 (MOI = 1), ATP (5 mM), or Poly(dA:dT) (1 µg/ml) according to the schedule in Figure 1. (G) IL-1β and (H) IL-8 levels were measured at 24 hours. |
| T13941 | 1026-1181 | Sentence | denotes | Statistical analysis was performed using two way ANOVA with Bonferroni correction for multiple comparisons. *, **, and *** signify P<0.05, 0.01, and 0.001. |
| T98 | 0-147 | Sentence | denotes | 10.1371/journal.pone.0037689.g006 Figure 6 NF-κB activation potentiates the degree of IL-1β production and secretion upon inflammasome activation. |
| T99 | 148-338 | Sentence | denotes | THP-1 reporter cells were primed overnight with heat-killed P. aeruginosa and stimulated the next day with live P. aeruginosa or additional heat-killed P. aeruginosa for the times indicated. |
| T100 | 339-463 | Sentence | denotes | Cell culture supernatants were assayed for (A) NF-κB/AP-1 activity, (B) IL-8, and (C) IL-1β secretion (n = 3–6 experiments). |
| T101 | 464-620 | Sentence | denotes | Using the same stimulation method, THP-1 reporter cells were treated with Bay11-7082 (20 µM) for 1 hour prior to priming with heat-killed PAO1 or live PAO1. |
| T102 | 621-732 | Sentence | denotes | Supernatants were assayed at 24 hours for (D) NF-κB/AP-1 activity, (E) IL-8, and (F) IL-1β secretion (n = 3–5). |
| T103 | 733-1025 | Sentence | denotes | PBMCs from CF patients (n = 11–15) and controls (n = 10–13) were treated with z-YVAD-fmk (20 µM) or Bay11-7082 (10 µM) and stimulated with live PAO1 (MOI = 1), ATP (5 mM), or Poly(dA:dT) (1 µg/ml) according to the schedule in Figure 1. (G) IL-1β and (H) IL-8 levels were measured at 24 hours. |
| T104 | 1026-1181 | Sentence | denotes | Statistical analysis was performed using two way ANOVA with Bonferroni correction for multiple comparisons. *, **, and *** signify P<0.05, 0.01, and 0.001. |