PMC:3359311 / 117-651
Annnotations
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T364 | 171-189 | P01584 | denotes | Interleukin-1 beta |
| T365 | 191-196 | P01584 | denotes | IL-1β |
| T366 | 263-268 | P01584 | denotes | IL-1β |
| T367 | 354-359 | P01584 | denotes | IL-1β |
| T368 | 452-457 | P01584 | denotes | IL-1β |
bionlp-st-ge-2016-reference
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T40 | 171-189 | Protein | denotes | Interleukin-1 beta | |
| T41 | 191-196 | Protein | denotes | IL-1β | |
| T42 | 230-239 | Localization | denotes | Secretion | |
| T43 | 263-268 | Protein | denotes | IL-1β | |
| T44 | 269-277 | Regulation | denotes | involves | |
| T45 | 354-359 | Protein | denotes | IL-1β | |
| T46 | 443-451 | Positive_regulation | denotes | mediated | true |
| T47 | 452-457 | Protein | denotes | IL-1β | |
| T48 | 458-468 | Gene_expression | denotes | production | |
| R25 | T41 | T40 | equivalentTo | IL-1β,Interleukin-1 beta | |
| R26 | T42 | T44 | themeOf | Secretion,involves | |
| R27 | T43 | T42 | themeOf | IL-1β,Secretion | |
| R28 | T47 | T48 | themeOf | IL-1β,production | |
| R29 | T48 | T46 | themeOf | production,mediated |
bionlp-st-ge-2016-reference-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T802 | 171-189 | Protein | denotes | Interleukin-1 beta |
| T803 | 191-196 | Protein | denotes | IL-1β |
| T804 | 220-228 | Positive_regulation | denotes | mediator |
| T805 | 220-228 | Positive_regulation | denotes | mediator |
| T806 | 263-268 | Protein | denotes | IL-1β |
| T807 | 230-239 | Localization | denotes | Secretion |
| T808 | 354-359 | Protein | denotes | IL-1β |
| R667 | T802 | T804 | themeOf | Interleukin-1 beta,mediator |
| R668 | T803 | T805 | themeOf | IL-1β,mediator |
| R669 | T806 | T807 | themeOf | IL-1β,Secretion |
events-check-again
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T770 | 171-189 | Protein | denotes | Interleukin-1 beta | |
| T771 | 191-196 | Protein | denotes | IL-1β | |
| T772 | 230-239 | Localization | denotes | Secretion | |
| T773 | 263-268 | Protein | denotes | IL-1β | |
| T774 | 269-277 | Regulation | denotes | involves | |
| T775 | 354-359 | Protein | denotes | IL-1β | |
| T776 | 443-451 | Positive_regulation | denotes | mediated | true |
| T777 | 452-457 | Protein | denotes | IL-1β | |
| T778 | 458-468 | Gene_expression | denotes | production | |
| R647 | T771 | T770 | equivalentTo | IL-1β,Interleukin-1 beta | |
| R648 | T772 | T774 | themeOf | Secretion,involves | |
| R649 | T773 | T772 | themeOf | IL-1β,Secretion | |
| R650 | T777 | T778 | themeOf | IL-1β,production | |
| R651 | T778 | T776 | themeOf | production,mediated |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T694 | 149-164 | http://purl.bioontology.org/ontology/ICD10/E84 | denotes | cystic fibrosis |
| T695 | 149-164 | http://purl.bioontology.org/ontology/ICD10/E84.9 | denotes | cystic fibrosis |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T688 | 496-500 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T680 | 11-23 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | Inflammation |
| T681 | 171-189 | http://purl.obolibrary.org/obo/GO_0050720 | denotes | Interleukin-1 beta |
| T682 | 171-189 | http://purl.obolibrary.org/obo/GO_0050702 | denotes | Interleukin-1 beta |
| T683 | 183-193 | http://purl.obolibrary.org/obo/GO_0032611 | denotes | 1 beta (IL |
| T684 | 230-239 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | Secretion |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T386 | 0-10 | NNP | denotes | Background |
| T387 | 11-23 | NNP | denotes | Inflammation |
| T388 | 24-27 | CC | denotes | and |
| T389 | 28-37 | NN | denotes | infection |
| T390 | 38-41 | VBP | denotes | are |
| T391 | 42-47 | JJ | denotes | major |
| T392 | 48-60 | NNS | denotes | determinants |
| T393 | 61-63 | IN | denotes | of |
| T394 | 64-71 | NN | denotes | disease |
| T395 | 72-80 | NN | denotes | severity |
| T396 | 81-84 | CC | denotes | and |
| T397 | 85-97 | RB | denotes | consequently |
| T398 | 97-98 | , | denotes | , |
| T399 | 99-102 | DT | denotes | the |
| T400 | 103-110 | NN | denotes | quality |
| T401 | 111-113 | IN | denotes | of |
| T402 | 114-118 | NN | denotes | life |
| T403 | 119-122 | CC | denotes | and |
| T404 | 123-130 | NN | denotes | outcome |
| T405 | 131-134 | IN | denotes | for |
| T406 | 135-143 | NNS | denotes | patients |
| T407 | 144-148 | IN | denotes | with |
| T408 | 149-155 | JJ | denotes | cystic |
| T409 | 156-164 | NN | denotes | fibrosis |
| T410 | 165-166 | -LRB- | denotes | ( |
| T411 | 166-168 | NNP | denotes | CF |
| T412 | 168-169 | -RRB- | denotes | ) |
| T413 | 169-170 | . | denotes | . |
| T414 | 171-184 | NN | denotes | Interleukin-1 |
| T415 | 185-189 | NN | denotes | beta |
| T416 | 190-191 | -LRB- | denotes | ( |
| T417 | 191-196 | NN | denotes | IL-1β |
| T418 | 196-197 | -RRB- | denotes | ) |
| T419 | 198-200 | VBZ | denotes | is |
| T420 | 201-202 | DT | denotes | a |
| T421 | 203-206 | JJ | denotes | key |
| T422 | 207-219 | JJ | denotes | inflammatory |
| T423 | 220-228 | NN | denotes | mediator |
| T424 | 228-229 | . | denotes | . |
| T425 | 230-239 | NNP | denotes | Secretion |
| T426 | 240-242 | IN | denotes | of |
| T427 | 243-255 | RB | denotes | biologically |
| T428 | 256-262 | JJ | denotes | active |
| T429 | 263-268 | JJ | denotes | IL-1β |
| T430 | 269-277 | VBZ | denotes | involves |
| T431 | 278-299 | JJ | denotes | inflammasome-mediated |
| T432 | 300-310 | NN | denotes | processing |
| T433 | 310-311 | . | denotes | . |
| T434 | 312-318 | NNP | denotes | Little |
| T435 | 319-321 | VBZ | denotes | is |
| T436 | 322-327 | VBN | denotes | known |
| T437 | 328-333 | IN | denotes | about |
| T438 | 334-337 | DT | denotes | the |
| T439 | 338-350 | NN | denotes | contribution |
| T440 | 351-353 | IN | denotes | of |
| T441 | 354-359 | NN | denotes | IL-1β |
| T442 | 360-363 | CC | denotes | and |
| T443 | 364-367 | DT | denotes | the |
| T444 | 368-381 | NNS | denotes | inflammasomes |
| T445 | 382-384 | IN | denotes | in |
| T446 | 385-387 | NNP | denotes | CF |
| T447 | 388-400 | JJ | denotes | inflammatory |
| T448 | 401-408 | NN | denotes | disease |
| T449 | 408-409 | . | denotes | . |
| T450 | 410-414 | DT | denotes | This |
| T451 | 415-420 | NN | denotes | study |
| T452 | 421-429 | VBZ | denotes | examines |
| T453 | 430-451 | JJ | denotes | inflammasome-mediated |
| T454 | 452-457 | JJ | denotes | IL-1β |
| T455 | 458-468 | NN | denotes | production |
| T456 | 469-471 | IN | denotes | in |
| T457 | 472-474 | NNP | denotes | CF |
| T458 | 475-484 | JJ | denotes | bronchial |
| T459 | 485-495 | JJ | denotes | epithelial |
| T460 | 496-500 | NN | denotes | cell |
| T461 | 501-506 | NNS | denotes | lines |
| T462 | 507-510 | CC | denotes | and |
| T463 | 511-516 | JJ | denotes | human |
| T464 | 517-525 | NNS | denotes | patients |
| T465 | 526-530 | IN | denotes | with |
| T466 | 531-534 | NNP | denotes | CF. |
| R324 | T386 | T387 | compound | Background,Inflammation |
| R326 | T388 | T387 | cc | and,Inflammation |
| R327 | T389 | T387 | conj | infection,Inflammation |
| R328 | T390 | T390 | ROOT | are,are |
| R329 | T391 | T392 | amod | major,determinants |
| R330 | T392 | T390 | attr | determinants,are |
| R331 | T393 | T392 | prep | of,determinants |
| R332 | T394 | T395 | compound | disease,severity |
| R333 | T395 | T393 | pobj | severity,of |
| R334 | T396 | T390 | cc | and,are |
| R335 | T397 | T400 | advmod | consequently,quality |
| R336 | T398 | T400 | punct | ",",quality |
| R337 | T399 | T400 | det | the,quality |
| R338 | T400 | T390 | conj | quality,are |
| R339 | T401 | T400 | prep | of,quality |
| R340 | T402 | T401 | pobj | life,of |
| R341 | T403 | T402 | cc | and,life |
| R342 | T404 | T400 | conj | outcome,quality |
| R343 | T405 | T400 | prep | for,quality |
| R344 | T406 | T405 | pobj | patients,for |
| R345 | T407 | T406 | prep | with,patients |
| R346 | T408 | T409 | compound | cystic,fibrosis |
| R347 | T409 | T407 | pobj | fibrosis,with |
| R348 | T410 | T411 | punct | (,CF |
| R349 | T411 | T409 | appos | CF,fibrosis |
| R350 | T412 | T400 | punct | ),quality |
| R351 | T413 | T390 | punct | .,are |
| R352 | T414 | T415 | compound | Interleukin-1,beta |
| R353 | T415 | T419 | nsubj | beta,is |
| R354 | T416 | T417 | punct | (,IL-1β |
| R355 | T417 | T415 | appos | IL-1β,beta |
| R356 | T418 | T417 | punct | ),IL-1β |
| R357 | T419 | T419 | ROOT | is,is |
| R358 | T420 | T423 | det | a,mediator |
| R359 | T421 | T423 | amod | key,mediator |
| R360 | T422 | T423 | amod | inflammatory,mediator |
| R361 | T423 | T419 | attr | mediator,is |
| R362 | T424 | T419 | punct | .,is |
| R363 | T425 | T430 | nsubj | Secretion,involves |
| R364 | T426 | T425 | prep | of,Secretion |
| R365 | T427 | T428 | advmod | biologically,active |
| R366 | T428 | T429 | amod | active,IL-1β |
| R367 | T429 | T426 | pobj | IL-1β,of |
| R368 | T430 | T430 | ROOT | involves,involves |
| R369 | T431 | T432 | amod | inflammasome-mediated,processing |
| R370 | T432 | T430 | dobj | processing,involves |
| R371 | T433 | T430 | punct | .,involves |
| R372 | T434 | T436 | nsubjpass | Little,known |
| R373 | T435 | T436 | auxpass | is,known |
| R374 | T436 | T436 | ROOT | known,known |
| R375 | T437 | T436 | prep | about,known |
| R376 | T438 | T439 | det | the,contribution |
| R377 | T439 | T437 | pobj | contribution,about |
| R378 | T440 | T439 | prep | of,contribution |
| R379 | T441 | T440 | pobj | IL-1β,of |
| R380 | T442 | T441 | cc | and,IL-1β |
| R381 | T443 | T444 | det | the,inflammasomes |
| R382 | T444 | T441 | conj | inflammasomes,IL-1β |
| R383 | T445 | T444 | prep | in,inflammasomes |
| R384 | T446 | T448 | nmod | CF,disease |
| R385 | T447 | T448 | amod | inflammatory,disease |
| R386 | T448 | T445 | pobj | disease,in |
| R387 | T449 | T436 | punct | .,known |
| R388 | T450 | T451 | det | This,study |
| R389 | T451 | T452 | nsubj | study,examines |
| R390 | T452 | T452 | ROOT | examines,examines |
| R391 | T453 | T455 | amod | inflammasome-mediated,production |
| R392 | T454 | T455 | compound | IL-1β,production |
| R393 | T455 | T452 | dobj | production,examines |
| R394 | T456 | T455 | prep | in,production |
| R395 | T457 | T461 | nmod | CF,lines |
| R396 | T458 | T461 | amod | bronchial,lines |
| R397 | T459 | T461 | amod | epithelial,lines |
| R398 | T460 | T461 | compound | cell,lines |
| R399 | T461 | T456 | pobj | lines,in |
| R400 | T462 | T461 | cc | and,lines |
| R401 | T463 | T464 | amod | human,patients |
| R402 | T464 | T461 | conj | patients,lines |
| R403 | T465 | T455 | prep | with,production |
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T97 | 0-10 | NN | denotes | Background |
| T98 | 11-23 | NN | denotes | Inflammation |
| T99 | 24-27 | CC | denotes | and |
| T100 | 28-37 | NN | denotes | infection |
| T101 | 38-41 | VB | denotes | are |
| T102 | 42-47 | JJ | denotes | major |
| T103 | 48-60 | NN | denotes | determinants |
| T104 | 61-63 | IN | denotes | of |
| T105 | 64-71 | NN | denotes | disease |
| T106 | 72-80 | NN | denotes | severity |
| T107 | 81-84 | CC | denotes | and |
| T108 | 85-97 | RB | denotes | consequently |
| T109 | 97-98 | -COMMA- | denotes | , |
| T110 | 99-102 | DT | denotes | the |
| T111 | 103-110 | NN | denotes | quality |
| T112 | 111-113 | IN | denotes | of |
| T113 | 114-118 | NN | denotes | life |
| T114 | 119-122 | CC | denotes | and |
| T115 | 123-130 | NN | denotes | outcome |
| T116 | 131-134 | IN | denotes | for |
| T117 | 135-143 | NN | denotes | patients |
| T118 | 144-148 | IN | denotes | with |
| T119 | 149-155 | JJ | denotes | cystic |
| T120 | 156-164 | NN | denotes | fibrosis |
| T121 | 165-166 | -LRB- | denotes | ( |
| T122 | 166-168 | NN | denotes | CF |
| T123 | 168-169 | -RRB- | denotes | ) |
| T124 | 171-184 | NN | denotes | Interleukin-1 |
| T125 | 185-189 | NN | denotes | beta |
| T126 | 190-191 | -LRB- | denotes | ( |
| T127 | 191-196 | NN | denotes | IL-1β |
| T128 | 196-197 | -RRB- | denotes | ) |
| T129 | 198-200 | VB | denotes | is |
| T130 | 201-202 | DT | denotes | a |
| T131 | 203-206 | JJ | denotes | key |
| T132 | 207-219 | JJ | denotes | inflammatory |
| T133 | 220-228 | NN | denotes | mediator |
| T134 | 230-239 | NN | denotes | Secretion |
| T135 | 240-242 | IN | denotes | of |
| T136 | 243-255 | RB | denotes | biologically |
| T137 | 256-262 | JJ | denotes | active |
| T138 | 263-268 | NN | denotes | IL-1β |
| T139 | 269-277 | VB | denotes | involves |
| T140 | 278-299 | JJ | denotes | inflammasome-mediated |
| T141 | 300-310 | NN | denotes | processing |
| T142 | 312-318 | JJ | denotes | Little |
| T143 | 319-321 | VB | denotes | is |
| T144 | 322-327 | VB | denotes | known |
| T145 | 328-333 | IN | denotes | about |
| T146 | 334-337 | DT | denotes | the |
| T147 | 338-350 | NN | denotes | contribution |
| T148 | 351-353 | IN | denotes | of |
| T149 | 354-359 | NN | denotes | IL-1β |
| T150 | 360-363 | CC | denotes | and |
| T151 | 364-367 | DT | denotes | the |
| T152 | 368-381 | NN | denotes | inflammasomes |
| T153 | 382-384 | IN | denotes | in |
| T154 | 385-387 | NN | denotes | CF |
| T155 | 388-400 | JJ | denotes | inflammatory |
| T156 | 401-408 | NN | denotes | disease |
| T157 | 410-414 | DT | denotes | This |
| T158 | 415-420 | NN | denotes | study |
| T159 | 421-429 | VB | denotes | examines |
| T160 | 430-451 | JJ | denotes | inflammasome-mediated |
| T161 | 452-457 | NN | denotes | IL-1β |
| T162 | 458-468 | NN | denotes | production |
| T163 | 469-471 | IN | denotes | in |
| T164 | 472-474 | NN | denotes | CF |
| T165 | 475-484 | JJ | denotes | bronchial |
| T166 | 485-495 | JJ | denotes | epithelial |
| T167 | 496-500 | NN | denotes | cell |
| T168 | 501-506 | NN | denotes | lines |
| T169 | 507-510 | CC | denotes | and |
| T170 | 511-516 | JJ | denotes | human |
| T171 | 517-525 | NN | denotes | patients |
| T172 | 526-530 | IN | denotes | with |
| T173 | 531-533 | NN | denotes | CF |
| R52 | T98 | T99 | arg1Of | Inflammation,and |
| R53 | T99 | T101 | arg1Of | and,are |
| R54 | T100 | T99 | arg2Of | infection,and |
| R55 | T103 | T101 | arg2Of | determinants,are |
| R56 | T103 | T102 | arg1Of | determinants,major |
| R57 | T103 | T104 | arg1Of | determinants,of |
| R58 | T103 | T108 | arg1Of | determinants,consequently |
| R59 | T103 | T109 | arg1Of | determinants,"," |
| R60 | T104 | T107 | arg1Of | of,and |
| R61 | T106 | T104 | arg2Of | severity,of |
| R62 | T106 | T105 | arg1Of | severity,disease |
| R63 | T108 | T107 | arg2Of | consequently,and |
| R64 | T111 | T109 | arg2Of | quality,"," |
| R65 | T111 | T110 | arg1Of | quality,the |
| R66 | T111 | T112 | arg1Of | quality,of |
| R67 | T111 | T116 | arg1Of | quality,for |
| R68 | T113 | T114 | arg1Of | life,and |
| R69 | T114 | T112 | arg2Of | and,of |
| R70 | T115 | T114 | arg2Of | outcome,and |
| R71 | T117 | T116 | arg2Of | patients,for |
| R72 | T117 | T118 | arg1Of | patients,with |
| R73 | T120 | T118 | arg2Of | fibrosis,with |
| R74 | T120 | T119 | arg1Of | fibrosis,cystic |
| R75 | T120 | T121 | arg1Of | fibrosis,( |
| R76 | T122 | T121 | arg2Of | CF,( |
| R77 | T123 | T121 | arg3Of | ),( |
| R78 | T125 | T124 | arg1Of | beta,Interleukin-1 |
| R79 | T125 | T126 | arg1Of | beta,( |
| R80 | T125 | T129 | arg1Of | beta,is |
| R81 | T127 | T126 | arg2Of | IL-1β,( |
| R82 | T128 | T126 | arg3Of | ),( |
| R83 | T133 | T129 | arg2Of | mediator,is |
| R84 | T133 | T130 | arg1Of | mediator,a |
| R85 | T133 | T131 | arg1Of | mediator,key |
| R86 | T133 | T132 | arg1Of | mediator,inflammatory |
| R87 | T134 | T135 | arg1Of | Secretion,of |
| R88 | T134 | T139 | arg1Of | Secretion,involves |
| R89 | T137 | T136 | arg1Of | active,biologically |
| R90 | T138 | T135 | arg2Of | IL-1β,of |
| R91 | T138 | T137 | arg1Of | IL-1β,active |
| R92 | T141 | T139 | arg2Of | processing,involves |
| R93 | T141 | T140 | arg1Of | processing,inflammasome-mediated |
| R94 | T142 | T143 | arg1Of | Little,is |
| R95 | T142 | T144 | arg2Of | Little,known |
| R96 | T144 | T143 | arg2Of | known,is |
| R97 | T144 | T145 | arg1Of | known,about |
| R98 | T147 | T145 | arg2Of | contribution,about |
| R99 | T147 | T146 | arg1Of | contribution,the |
| R100 | T147 | T148 | arg1Of | contribution,of |
| R101 | T147 | T153 | arg1Of | contribution,in |
| R102 | T149 | T150 | arg1Of | IL-1β,and |
| R103 | T150 | T148 | arg2Of | and,of |
| R104 | T152 | T150 | arg2Of | inflammasomes,and |
| R105 | T152 | T151 | arg1Of | inflammasomes,the |
| R106 | T156 | T153 | arg2Of | disease,in |
| R107 | T156 | T154 | arg1Of | disease,CF |
| R108 | T156 | T155 | arg1Of | disease,inflammatory |
| R109 | T158 | T157 | arg1Of | study,This |
| R110 | T158 | T159 | arg1Of | study,examines |
| R111 | T162 | T159 | arg2Of | production,examines |
| R112 | T162 | T160 | arg1Of | production,inflammasome-mediated |
| R113 | T162 | T161 | arg1Of | production,IL-1β |
| R114 | T162 | T163 | arg1Of | production,in |
| R115 | T168 | T164 | arg1Of | lines,CF |
| R116 | T168 | T165 | arg1Of | lines,bronchial |
| R117 | T168 | T166 | arg1Of | lines,epithelial |
| R118 | T168 | T167 | arg1Of | lines,cell |
| R119 | T168 | T169 | arg1Of | lines,and |
| R120 | T169 | T163 | arg2Of | and,in |
| R121 | T171 | T169 | arg2Of | patients,and |
| R122 | T171 | T170 | arg1Of | patients,human |
| R123 | T171 | T172 | arg1Of | patients,with |
| R124 | T173 | T172 | arg2Of | CF,with |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T73 | 0-10 | Sentence | denotes | Background |
| T74 | 11-170 | Sentence | denotes | Inflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). |
| T75 | 171-229 | Sentence | denotes | Interleukin-1 beta (IL-1β) is a key inflammatory mediator. |
| T76 | 230-311 | Sentence | denotes | Secretion of biologically active IL-1β involves inflammasome-mediated processing. |
| T77 | 312-409 | Sentence | denotes | Little is known about the contribution of IL-1β and the inflammasomes in CF inflammatory disease. |
| T78 | 410-534 | Sentence | denotes | This study examines inflammasome-mediated IL-1β production in CF bronchial epithelial cell lines and human patients with CF. |
| T3 | 0-10 | Sentence | denotes | Background |
| T4 | 11-170 | Sentence | denotes | Inflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). |
| T5 | 171-229 | Sentence | denotes | Interleukin-1 beta (IL-1β) is a key inflammatory mediator. |
| T6 | 230-311 | Sentence | denotes | Secretion of biologically active IL-1β involves inflammasome-mediated processing. |
| T7 | 312-409 | Sentence | denotes | Little is known about the contribution of IL-1β and the inflammasomes in CF inflammatory disease. |
| T8 | 410-534 | Sentence | denotes | This study examines inflammasome-mediated IL-1β production in CF bronchial epithelial cell lines and human patients with CF. |