PMC:3359311 / 10426-12381
Annnotations
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3907 | 59-64 | P01584 | denotes | IL-1β |
T3908 | 536-541 | P01584 | denotes | IL-1β |
T3909 | 555-559 | P10145 | denotes | IL-8 |
T3910 | 676-681 | P01584 | denotes | IL-1β |
T3911 | 806-810 | P26993 | denotes | exsA |
T3912 | 888-893 | P01584 | denotes | IL-1β |
T3913 | 1017-1022 | P01584 | denotes | IL-1β |
T3914 | 1183-1188 | P01584 | denotes | IL-1β |
T3915 | 1192-1196 | P10145 | denotes | IL-8 |
T13748 | 1526-1531 | P01584 | denotes | IL-1β |
T13749 | 1720-1724 | P26993 | denotes | exsA |
T13750 | 1809-1813 | P26993 | denotes | exsA |
T13751 | 1933-1938 | P01584 | denotes | IL-1β |
T13752 | 1947-1951 | P10145 | denotes | IL-8 |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T3606 | 30-37 | Gene_expression | denotes | produce | |
T3607 | 38-47 | Positive_regulation | denotes | increased | true |
T3608 | 59-64 | Protein | denotes | IL-1β | |
T3609 | 507-514 | Gene_expression | denotes | produce | |
T3610 | 515-524 | Positive_regulation | denotes | increased | true |
T3611 | 536-541 | Protein | denotes | IL-1β | |
T3612 | 640-648 | Negative_regulation | denotes | decrease | |
T3613 | 676-681 | Protein | denotes | IL-1β | |
T3614 | 682-690 | Gene_expression | denotes | produced | |
T3615 | 703-717 | Positive_regulation | denotes | in response to | |
T3616 | 806-810 | Protein | denotes | exsA | |
T3617 | 863-871 | Gene_expression | denotes | produced | |
T3618 | 883-887 | Negative_regulation | denotes | less | |
T3619 | 888-893 | Protein | denotes | IL-1β | |
T3620 | 1003-1009 | Positive_regulation | denotes | result | true |
T3621 | 1017-1022 | Protein | denotes | IL-1β | |
T3622 | 1023-1033 | Gene_expression | denotes | production | true |
T3623 | 1159-1168 | Positive_regulation | denotes | increased | true |
T3624 | 1159-1168 | Positive_regulation | denotes | increased | true |
T3625 | 1169-1179 | Gene_expression | denotes | production | |
T3626 | 1169-1179 | Gene_expression | denotes | production | |
T3627 | 1183-1188 | Protein | denotes | IL-1β | |
T3628 | 1192-1196 | Protein | denotes | IL-8 | |
T13633 | 1497-1504 | Gene_expression | denotes | produce | |
T13634 | 1505-1514 | Positive_regulation | denotes | increased | true |
T13635 | 1526-1531 | Protein | denotes | IL-1β | |
T13636 | 1712-1719 | Negative_regulation | denotes | lacking | |
T13637 | 1720-1724 | Protein | denotes | exsA | |
T13638 | 1801-1808 | Negative_regulation | denotes | lacking | |
T13639 | 1809-1813 | Protein | denotes | exsA | |
T13640 | 1933-1938 | Protein | denotes | IL-1β | |
R3115 | T3606 | T3607 | themeOf | produce,increased | |
R3116 | T3608 | T3606 | themeOf | IL-1β,produce | |
R3117 | T3609 | T3610 | themeOf | produce,increased | |
R3118 | T3611 | T3609 | themeOf | IL-1β,produce | |
R3119 | T3612 | T3615 | themeOf | decrease,in response to | |
R3120 | T3613 | T3614 | themeOf | IL-1β,produced | |
R3121 | T3614 | T3612 | themeOf | produced,decrease | |
R3122 | T3617 | T3618 | themeOf | produced,less | |
R3123 | T3619 | T3617 | themeOf | IL-1β,produced | |
R3124 | T3621 | T3622 | themeOf | IL-1β,production | |
R3125 | T3622 | T3620 | themeOf | production,result | |
R3126 | T3625 | T3623 | themeOf | production,increased | |
R3127 | T3626 | T3624 | themeOf | production,increased | |
R3128 | T3627 | T3625 | themeOf | IL-1β,production | |
R3129 | T3628 | T3626 | themeOf | IL-8,production | |
R12100 | T13633 | T13634 | themeOf | produce,increased | |
R12101 | T13635 | T13633 | themeOf | IL-1β,produce | |
R12102 | T13637 | T13636 | themeOf | exsA,lacking | |
R12103 | T13639 | T13638 | themeOf | exsA,lacking |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4279 | 59-64 | Protein | denotes | IL-1β |
T4280 | 30-37 | Gene_expression | denotes | produce |
T4281 | 38-47 | Positive_regulation | denotes | increased |
T4282 | 166-171 | Protein | denotes | NF-κB |
T4283 | 156-165 | Positive_regulation | denotes | increased |
T4284 | 211-220 | Localization | denotes | secretion |
T4285 | 156-165 | Positive_regulation | denotes | increased |
T4286 | 358-362 | Protein | denotes | PAO1 |
T4287 | 410-415 | Protein | denotes | NLRC4 |
T4288 | 417-422 | Protein | denotes | NLRP3 |
T4289 | 397-405 | Positive_regulation | denotes | activate |
T4290 | 397-405 | Positive_regulation | denotes | activate |
T4291 | 536-541 | Protein | denotes | IL-1β |
T4292 | 543-550 | Protein | denotes | Fig. 5a |
T4293 | 555-559 | Protein | denotes | IL-8 |
T4294 | 561-568 | Protein | denotes | Fig. 5b |
T4295 | 507-514 | Gene_expression | denotes | produce |
T4296 | 507-514 | Gene_expression | denotes | produce |
T4297 | 507-514 | Gene_expression | denotes | produce |
T4298 | 507-514 | Gene_expression | denotes | produce |
T4299 | 515-524 | Positive_regulation | denotes | increased |
T4300 | 515-524 | Positive_regulation | denotes | increased |
T4301 | 515-524 | Positive_regulation | denotes | increased |
T4302 | 515-524 | Positive_regulation | denotes | increased |
T4303 | 676-681 | Protein | denotes | IL-1β |
T4304 | 682-690 | Gene_expression | denotes | produced |
T4305 | 806-810 | Protein | denotes | exsA |
T4306 | 812-821 | Protein | denotes | PAO1ΔexsA |
T4307 | 888-893 | Protein | denotes | IL-1β |
T4308 | 919-923 | Protein | denotes | PAO1 |
T4309 | 800-805 | Negative_regulation | denotes | lacks |
T4310 | 800-805 | Negative_regulation | denotes | lacks |
T4311 | 863-871 | Gene_expression | denotes | produced |
T4312 | 1017-1022 | Protein | denotes | IL-1β |
T4313 | 1023-1033 | Gene_expression | denotes | production |
T4314 | 1003-1009 | Positive_regulation | denotes | result |
T4315 | 1183-1188 | Protein | denotes | IL-1β |
T4316 | 1192-1196 | Protein | denotes | IL-8 |
T4317 | 1277-1282 | Protein | denotes | NF-κB |
T4318 | 1169-1179 | Gene_expression | denotes | production |
T4319 | 1169-1179 | Gene_expression | denotes | production |
T4320 | 1159-1168 | Positive_regulation | denotes | increased |
T4321 | 1159-1168 | Positive_regulation | denotes | increased |
T4322 | 1348-1357 | Protein | denotes | caspase-1 |
T13902 | 1526-1531 | Protein | denotes | IL-1β |
T13903 | 1497-1504 | Gene_expression | denotes | produce |
T13904 | 1505-1514 | Positive_regulation | denotes | increased |
T13905 | 1696-1711 | Protein | denotes | aeruginosa PAO1 |
T13906 | 1720-1724 | Protein | denotes | exsA |
T13907 | 1712-1719 | Negative_regulation | denotes | lacking |
T13908 | 1712-1719 | Negative_regulation | denotes | lacking |
T13909 | 1809-1813 | Protein | denotes | exsA |
T13910 | 1801-1808 | Negative_regulation | denotes | lacking |
R3727 | T4279 | T4280 | themeOf | IL-1β,produce |
R3728 | T4279 | T4281 | themeOf | IL-1β,increased |
R3729 | T4282 | T4283 | themeOf | NF-κB,increased |
R3730 | T4282 | T4284 | themeOf | NF-κB,secretion |
R3731 | T4284 | T4285 | themeOf | secretion,increased |
R3732 | T4287 | T4289 | themeOf | NLRC4,activate |
R3733 | T4288 | T4290 | themeOf | NLRP3,activate |
R3734 | T4291 | T4295 | themeOf | IL-1β,produce |
R3735 | T4291 | T4299 | themeOf | IL-1β,increased |
R3736 | T4292 | T4296 | themeOf | Fig. 5a,produce |
R3737 | T4292 | T4300 | themeOf | Fig. 5a,increased |
R3738 | T4293 | T4297 | themeOf | IL-8,produce |
R3739 | T4293 | T4301 | themeOf | IL-8,increased |
R3740 | T4294 | T4298 | themeOf | Fig. 5b,produce |
R3741 | T4294 | T4302 | themeOf | Fig. 5b,increased |
R3742 | T4303 | T4304 | themeOf | IL-1β,produced |
R3743 | T4305 | T4309 | themeOf | exsA,lacks |
R3744 | T4306 | T4310 | themeOf | PAO1ΔexsA,lacks |
R3745 | T4307 | T4311 | themeOf | IL-1β,produced |
R3746 | T4312 | T4313 | themeOf | IL-1β,production |
R3747 | T4313 | T4314 | themeOf | production,result |
R3748 | T4315 | T4318 | themeOf | IL-1β,production |
R3749 | T4316 | T4319 | themeOf | IL-8,production |
R3750 | T4318 | T4320 | themeOf | production,increased |
R3751 | T4319 | T4321 | themeOf | production,increased |
R12339 | T13902 | T13903 | themeOf | IL-1β,produce |
R12340 | T13902 | T13904 | themeOf | IL-1β,increased |
R12341 | T13905 | T13907 | themeOf | aeruginosa PAO1,lacking |
R12342 | T13906 | T13908 | themeOf | exsA,lacking |
R12343 | T13909 | T13910 | themeOf | exsA,lacking |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T4256 | 30-37 | Gene_expression | denotes | produce | |
T4257 | 38-47 | Positive_regulation | denotes | increased | true |
T4258 | 59-64 | Protein | denotes | IL-1β | |
T4259 | 507-514 | Gene_expression | denotes | produce | |
T4260 | 515-524 | Positive_regulation | denotes | increased | true |
T4261 | 536-541 | Protein | denotes | IL-1β | |
T4262 | 640-648 | Negative_regulation | denotes | decrease | |
T4263 | 676-681 | Protein | denotes | IL-1β | |
T4264 | 682-690 | Gene_expression | denotes | produced | |
T4265 | 703-717 | Positive_regulation | denotes | in response to | |
T4266 | 806-810 | Protein | denotes | exsA | |
T4267 | 863-871 | Gene_expression | denotes | produced | |
T4268 | 883-887 | Negative_regulation | denotes | less | |
T4269 | 888-893 | Protein | denotes | IL-1β | |
T4270 | 1003-1009 | Positive_regulation | denotes | result | true |
T4271 | 1017-1022 | Protein | denotes | IL-1β | |
T4272 | 1023-1033 | Gene_expression | denotes | production | true |
T4273 | 1159-1168 | Positive_regulation | denotes | increased | true |
T4274 | 1159-1168 | Positive_regulation | denotes | increased | true |
T4275 | 1169-1179 | Gene_expression | denotes | production | |
T4276 | 1169-1179 | Gene_expression | denotes | production | |
T4277 | 1183-1188 | Protein | denotes | IL-1β | |
T4278 | 1192-1196 | Protein | denotes | IL-8 | |
T13894 | 1497-1504 | Gene_expression | denotes | produce | |
T13895 | 1505-1514 | Positive_regulation | denotes | increased | true |
T13896 | 1526-1531 | Protein | denotes | IL-1β | |
T13897 | 1712-1719 | Negative_regulation | denotes | lacking | |
T13898 | 1720-1724 | Protein | denotes | exsA | |
T13899 | 1801-1808 | Negative_regulation | denotes | lacking | |
T13900 | 1809-1813 | Protein | denotes | exsA | |
T13901 | 1933-1938 | Protein | denotes | IL-1β | |
R3712 | T4256 | T4257 | themeOf | produce,increased | |
R3713 | T4258 | T4256 | themeOf | IL-1β,produce | |
R3714 | T4259 | T4260 | themeOf | produce,increased | |
R3715 | T4261 | T4259 | themeOf | IL-1β,produce | |
R3716 | T4262 | T4265 | themeOf | decrease,in response to | |
R3717 | T4263 | T4264 | themeOf | IL-1β,produced | |
R3718 | T4264 | T4262 | themeOf | produced,decrease | |
R3719 | T4267 | T4268 | themeOf | produced,less | |
R3720 | T4269 | T4267 | themeOf | IL-1β,produced | |
R3721 | T4271 | T4272 | themeOf | IL-1β,production | |
R3722 | T4272 | T4270 | themeOf | production,result | |
R3723 | T4275 | T4273 | themeOf | production,increased | |
R3724 | T4276 | T4274 | themeOf | production,increased | |
R3725 | T4277 | T4275 | themeOf | IL-1β,production | |
R3726 | T4278 | T4276 | themeOf | IL-8,production | |
R12335 | T13894 | T13895 | themeOf | produce,increased | |
R12336 | T13896 | T13894 | themeOf | IL-1β,produce | |
R12337 | T13898 | T13897 | themeOf | exsA,lacking | |
R12338 | T13900 | T13899 | themeOf | exsA,lacking |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4207 | 697-702 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4208 | 555-559 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
T4209 | 1192-1196 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
T13877 | 1947-1951 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4203 | 202-220 | http://purl.obolibrary.org/obo/GO_0050663 | denotes | cytokine secretion |
T4204 | 211-220 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
T4205 | 852-861 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
T4206 | 706-721 | http://purl.obolibrary.org/obo/GO_0032496 | denotes | response to LPS |
T13876 | 1837-1846 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3916 | 0-5 | NNS | denotes | PBMCs |
T3917 | 6-10 | IN | denotes | from |
T3918 | 11-13 | NNP | denotes | CF |
T3919 | 14-22 | NNS | denotes | patients |
T3920 | 23-25 | VBP | denotes | do |
T3921 | 26-29 | RB | denotes | not |
T3922 | 30-37 | VB | denotes | produce |
T3923 | 38-47 | JJ | denotes | increased |
T3924 | 48-55 | NNS | denotes | amounts |
T3925 | 56-58 | IN | denotes | of |
T3926 | 59-64 | NN | denotes | IL-1β |
T3927 | 65-69 | IN | denotes | upon |
T3928 | 70-82 | JJ | denotes | inflammasome |
T3929 | 83-94 | NN | denotes | stimulation |
T3930 | 95-103 | JJ | denotes | Previous |
T3931 | 104-111 | NNS | denotes | studies |
T3932 | 112-116 | VBP | denotes | have |
T3933 | 117-122 | VBN | denotes | shown |
T3934 | 123-127 | IN | denotes | that |
T3935 | 128-131 | DT | denotes | the |
T3936 | 132-136 | NN | denotes | loss |
T3937 | 137-139 | IN | denotes | of |
T3938 | 140-144 | NNP | denotes | CFTR |
T3939 | 145-152 | NNS | denotes | results |
T3940 | 153-155 | IN | denotes | in |
T3941 | 156-165 | VBN | denotes | increased |
T3942 | 166-171 | NN | denotes | NF-κB |
T3943 | 172-180 | NN | denotes | activity |
T3944 | 181-184 | CC | denotes | and |
T3945 | 185-201 | JJ | denotes | pro-inflammatory |
T3946 | 202-210 | NN | denotes | cytokine |
T3947 | 211-220 | NN | denotes | secretion |
T3948 | 221-222 | NNP | denotes | [ |
T3949 | 222-223 | CD | denotes | 4 |
T3950 | 223-224 | NNP | denotes | ] |
T3951 | 224-225 | , | denotes | , |
T3952 | 226-227 | NNP | denotes | [ |
T3953 | 227-228 | CD | denotes | 5 |
T3954 | 228-229 | NNP | denotes | ] |
T3955 | 229-230 | , | denotes | , |
T3956 | 231-232 | NNP | denotes | [ |
T3957 | 232-234 | CD | denotes | 32 |
T3958 | 234-235 | NNP | denotes | ] |
T3959 | 235-236 | , | denotes | , |
T3960 | 237-238 | NNP | denotes | [ |
T3961 | 238-240 | CD | denotes | 36 |
T3962 | 240-241 | NNP | denotes | ] |
T3963 | 241-242 | , | denotes | , |
T3964 | 243-244 | NNP | denotes | [ |
T3965 | 244-246 | CD | denotes | 37 |
T3966 | 246-247 | NNP | denotes | ] |
T3967 | 247-248 | . | denotes | . |
T3968 | 249-251 | TO | denotes | To |
T3969 | 252-259 | RBR | denotes | further |
T3970 | 260-267 | VB | denotes | examine |
T3971 | 268-272 | DT | denotes | this |
T3972 | 273-285 | NN | denotes | relationship |
T3973 | 285-286 | , | denotes | , |
T3974 | 287-292 | NNP | denotes | PBMCs |
T3975 | 293-297 | IN | denotes | from |
T3976 | 298-300 | NNP | denotes | CF |
T3977 | 301-309 | NNS | denotes | patients |
T3978 | 310-313 | CC | denotes | and |
T3979 | 314-321 | JJ | denotes | healthy |
T3980 | 322-327 | NN | denotes | adult |
T3981 | 328-336 | NNS | denotes | controls |
T3982 | 337-341 | VBD | denotes | were |
T3983 | 342-352 | VBN | denotes | stimulated |
T3984 | 353-357 | IN | denotes | with |
T3985 | 358-362 | NNP | denotes | PAO1 |
T3986 | 362-363 | , | denotes | , |
T3987 | 364-371 | NNP | denotes | LPS+ATP |
T3988 | 371-372 | , | denotes | , |
T3989 | 373-376 | CC | denotes | and |
T3990 | 377-382 | NNP | denotes | LPS+P |
T3991 | 382-385 | NN | denotes | oly |
T3992 | 385-386 | -LRB- | denotes | ( |
T3993 | 386-388 | NN | denotes | dA |
T3994 | 388-389 | : | denotes | : |
T3995 | 389-391 | NN | denotes | dT |
T3996 | 391-392 | -RRB- | denotes | ) |
T3997 | 392-393 | , | denotes | , |
T3998 | 394-396 | TO | denotes | to |
T3999 | 397-405 | VB | denotes | activate |
T4000 | 406-409 | DT | denotes | the |
T4001 | 410-415 | NNP | denotes | NLRC4 |
T4002 | 415-416 | , | denotes | , |
T4003 | 417-422 | NNP | denotes | NLRP3 |
T4004 | 422-423 | , | denotes | , |
T4005 | 424-427 | CC | denotes | and |
T4006 | 428-432 | NNP | denotes | AIM2 |
T4007 | 433-446 | NNS | denotes | inflammasomes |
T4008 | 446-447 | , | denotes | , |
T4009 | 448-460 | RB | denotes | respectively |
T4010 | 460-461 | . | denotes | . |
T4011 | 462-464 | IN | denotes | By |
T4012 | 465-467 | CD | denotes | 24 |
T4013 | 468-473 | NNS | denotes | hours |
T4014 | 474-476 | IN | denotes | of |
T4015 | 477-488 | NN | denotes | stimulation |
T4016 | 488-489 | , | denotes | , |
T4017 | 490-492 | NNP | denotes | CF |
T4018 | 493-498 | NNP | denotes | PBMCs |
T4019 | 499-502 | VBD | denotes | did |
T4020 | 503-506 | RB | denotes | not |
T4021 | 507-514 | VB | denotes | produce |
T4022 | 515-524 | JJ | denotes | increased |
T4023 | 525-532 | NNS | denotes | amounts |
T4024 | 533-535 | IN | denotes | of |
T4025 | 536-541 | NN | denotes | IL-1β |
T4026 | 542-543 | -LRB- | denotes | ( |
T4027 | 543-547 | NNP | denotes | Fig. |
T4028 | 548-550 | CD | denotes | 5a |
T4029 | 550-551 | -RRB- | denotes | ) |
T4030 | 552-554 | CC | denotes | or |
T4031 | 555-559 | NN | denotes | IL-8 |
T4032 | 560-561 | -LRB- | denotes | ( |
T4033 | 561-565 | NNP | denotes | Fig. |
T4034 | 566-568 | CD | denotes | 5b |
T4035 | 568-569 | -RRB- | denotes | ) |
T4036 | 570-574 | WRB | denotes | when |
T4037 | 575-583 | VBN | denotes | compared |
T4038 | 584-586 | TO | denotes | to |
T4039 | 587-594 | JJ | denotes | healthy |
T4040 | 595-603 | NNS | denotes | controls |
T4041 | 603-604 | . | denotes | . |
T4042 | 605-612 | RB | denotes | However |
T4043 | 612-613 | , | denotes | , |
T4044 | 614-616 | PRP | denotes | we |
T4045 | 617-620 | VBD | denotes | did |
T4046 | 621-627 | VB | denotes | notice |
T4047 | 628-629 | DT | denotes | a |
T4048 | 630-639 | NN | denotes | transient |
T4049 | 640-648 | NN | denotes | decrease |
T4050 | 649-650 | -LRB- | denotes | ( |
T4051 | 650-651 | NNP | denotes | P |
T4052 | 651-652 | CD | denotes | < |
T4053 | 652-657 | CD | denotes | 0.001 |
T4054 | 657-658 | -RRB- | denotes | ) |
T4055 | 659-661 | IN | denotes | in |
T4056 | 662-665 | DT | denotes | the |
T4057 | 666-672 | NN | denotes | amount |
T4058 | 673-675 | IN | denotes | of |
T4059 | 676-681 | JJ | denotes | IL-1β |
T4060 | 682-690 | VBN | denotes | produced |
T4061 | 691-693 | IN | denotes | by |
T4062 | 694-696 | NNP | denotes | CF |
T4063 | 697-702 | NNS | denotes | cells |
T4064 | 703-705 | IN | denotes | in |
T4065 | 706-714 | NN | denotes | response |
T4066 | 715-717 | TO | denotes | to |
T4067 | 718-725 | NNP | denotes | LPS+ATP |
T4068 | 726-728 | IN | denotes | at |
T4069 | 729-730 | CD | denotes | 6 |
T4070 | 731-736 | NNS | denotes | hours |
T4071 | 737-738 | -LRB- | denotes | ( |
T4072 | 738-742 | NNS | denotes | data |
T4073 | 743-746 | RB | denotes | not |
T4074 | 747-752 | VBN | denotes | shown |
T4075 | 752-753 | -RRB- | denotes | ) |
T4076 | 753-754 | . | denotes | . |
T4077 | 755-766 | NN | denotes | Stimulation |
T4078 | 767-769 | IN | denotes | of |
T4079 | 770-775 | NNS | denotes | PBMCs |
T4080 | 776-780 | IN | denotes | with |
T4081 | 781-783 | NNP | denotes | P. |
T4082 | 784-794 | NN | denotes | aeruginosa |
T4083 | 795-799 | WDT | denotes | that |
T4084 | 800-805 | VBZ | denotes | lacks |
T4085 | 806-810 | NNP | denotes | exsA |
T4086 | 811-812 | -LRB- | denotes | ( |
T4087 | 812-821 | NNP | denotes | PAO1ΔexsA |
T4088 | 821-822 | -RRB- | denotes | ) |
T4089 | 822-823 | , | denotes | , |
T4090 | 824-825 | DT | denotes | a |
T4091 | 826-829 | JJ | denotes | key |
T4092 | 830-839 | NN | denotes | regulator |
T4093 | 840-842 | IN | denotes | of |
T4094 | 843-847 | NN | denotes | type |
T4095 | 848-851 | NNP | denotes | III |
T4096 | 852-861 | NN | denotes | secretion |
T4097 | 861-862 | , | denotes | , |
T4098 | 863-871 | VBD | denotes | produced |
T4099 | 872-882 | JJ | denotes | three-fold |
T4100 | 883-887 | RBR | denotes | less |
T4101 | 888-893 | JJ | denotes | IL-1β |
T4102 | 894-902 | VBN | denotes | compared |
T4103 | 903-905 | TO | denotes | to |
T4104 | 906-909 | DT | denotes | the |
T4105 | 910-918 | JJ | denotes | parental |
T4106 | 919-923 | NNP | denotes | PAO1 |
T4107 | 924-930 | NN | denotes | strain |
T4108 | 931-933 | IN | denotes | by |
T4109 | 934-936 | CD | denotes | 24 |
T4110 | 937-942 | NNS | denotes | hours |
T4111 | 943-944 | -LRB- | denotes | ( |
T4112 | 944-948 | NNP | denotes | Fig. |
T4113 | 949-951 | CD | denotes | 5a |
T4114 | 951-952 | -RRB- | denotes | ) |
T4115 | 952-953 | . | denotes | . |
T4116 | 954-966 | JJ | denotes | Inflammasome |
T4117 | 967-978 | NN | denotes | stimulation |
T4118 | 979-986 | IN | denotes | without |
T4119 | 987-994 | VBG | denotes | priming |
T4120 | 995-998 | VBD | denotes | did |
T4121 | 999-1002 | RB | denotes | not |
T4122 | 1003-1009 | VB | denotes | result |
T4123 | 1010-1012 | IN | denotes | in |
T4124 | 1013-1016 | DT | denotes | any |
T4125 | 1017-1022 | JJ | denotes | IL-1β |
T4126 | 1023-1033 | NN | denotes | production |
T4127 | 1034-1036 | IN | denotes | in |
T4128 | 1037-1043 | CC | denotes | either |
T4129 | 1044-1046 | NNP | denotes | CF |
T4130 | 1047-1049 | CC | denotes | or |
T4131 | 1050-1057 | NN | denotes | control |
T4132 | 1058-1063 | NNS | denotes | PBMCs |
T4133 | 1063-1064 | . | denotes | . |
T4134 | 1065-1073 | JJ | denotes | Contrary |
T4135 | 1074-1076 | TO | denotes | to |
T4136 | 1077-1080 | PRP$ | denotes | our |
T4137 | 1081-1091 | NN | denotes | hypothesis |
T4138 | 1091-1092 | , | denotes | , |
T4139 | 1093-1098 | DT | denotes | these |
T4140 | 1099-1106 | NNS | denotes | results |
T4141 | 1107-1115 | VBP | denotes | indicate |
T4142 | 1116-1120 | IN | denotes | that |
T4143 | 1121-1126 | NNS | denotes | PBMCs |
T4144 | 1127-1131 | IN | denotes | from |
T4145 | 1132-1134 | NNP | denotes | CF |
T4146 | 1135-1143 | NNS | denotes | patients |
T4147 | 1144-1146 | VBP | denotes | do |
T4148 | 1147-1150 | RB | denotes | not |
T4149 | 1151-1158 | VB | denotes | display |
T4150 | 1159-1168 | VBN | denotes | increased |
T4151 | 1169-1179 | NN | denotes | production |
T4152 | 1180-1182 | IN | denotes | of |
T4153 | 1183-1188 | NN | denotes | IL-1β |
T4154 | 1189-1191 | CC | denotes | or |
T4155 | 1192-1196 | NN | denotes | IL-8 |
T4156 | 1197-1201 | IN | denotes | with |
T4157 | 1202-1214 | JJ | denotes | inflammasome |
T4158 | 1215-1225 | NN | denotes | activation |
T4159 | 1226-1229 | CC | denotes | nor |
T4160 | 1230-1232 | VBP | denotes | do |
T4161 | 1233-1237 | PRP | denotes | they |
T4162 | 1238-1245 | VBP | denotes | suggest |
T4163 | 1246-1249 | DT | denotes | any |
T4164 | 1250-1259 | VBN | denotes | increased |
T4165 | 1260-1265 | NN | denotes | basal |
T4166 | 1266-1268 | CC | denotes | or |
T4167 | 1269-1276 | JJ | denotes | induced |
T4168 | 1277-1282 | NN | denotes | NF-κB |
T4169 | 1283-1291 | NN | denotes | activity |
T4170 | 1291-1292 | . | denotes | . |
T4171 | 1293-1298 | DT | denotes | These |
T4172 | 1299-1306 | NNS | denotes | results |
T4173 | 1307-1310 | VBP | denotes | are |
T4174 | 1311-1321 | JJ | denotes | consistent |
T4175 | 1322-1326 | IN | denotes | with |
T4176 | 1327-1330 | PRP$ | denotes | our |
T4177 | 1331-1342 | NN | denotes | observation |
T4178 | 1343-1347 | IN | denotes | that |
T4179 | 1348-1357 | JJ | denotes | caspase-1 |
T4180 | 1358-1366 | NN | denotes | activity |
T4181 | 1367-1369 | VBZ | denotes | is |
T4182 | 1370-1373 | RB | denotes | not |
T4183 | 1374-1383 | JJ | denotes | different |
T4184 | 1384-1391 | IN | denotes | between |
T4185 | 1392-1394 | NNP | denotes | CF |
T4186 | 1395-1398 | CC | denotes | and |
T4187 | 1399-1406 | VB | denotes | control |
T4188 | 1407-1412 | NNP | denotes | PBMCs |
T4189 | 1413-1414 | -LRB- | denotes | ( |
T4190 | 1414-1418 | NNP | denotes | Fig. |
T4191 | 1419-1420 | CD | denotes | 4 |
T4192 | 1420-1421 | -RRB- | denotes | ) |
T4193 | 1421-1422 | . | denotes | . |
T13753 | 1467-1472 | NNS | denotes | PBMCs |
T13754 | 1473-1477 | IN | denotes | from |
T13755 | 1478-1480 | NNP | denotes | CF |
T13756 | 1481-1489 | NNS | denotes | patients |
T13757 | 1490-1492 | VBP | denotes | do |
T13758 | 1493-1496 | RB | denotes | not |
T13759 | 1497-1504 | VB | denotes | produce |
T13760 | 1505-1514 | JJ | denotes | increased |
T13761 | 1515-1522 | NNS | denotes | amounts |
T13762 | 1523-1525 | IN | denotes | of |
T13763 | 1526-1531 | NN | denotes | IL-1β |
T13764 | 1531-1532 | . | denotes | . |
T13765 | 1533-1538 | NNS | denotes | PBMCs |
T13766 | 1539-1543 | IN | denotes | from |
T13767 | 1544-1546 | NNP | denotes | CF |
T13768 | 1547-1555 | NNS | denotes | patients |
T13769 | 1556-1557 | -LRB- | denotes | ( |
T13770 | 1557-1558 | FW | denotes | n |
T13771 | 1559-1560 | SYM | denotes | = |
T13772 | 1561-1563 | CD | denotes | 17 |
T13773 | 1564-1566 | CD | denotes | 20 |
T13774 | 1566-1567 | -RRB- | denotes | ) |
T13775 | 1568-1571 | CC | denotes | and |
T13776 | 1572-1579 | JJ | denotes | healthy |
T13777 | 1580-1588 | NNS | denotes | controls |
T13778 | 1589-1590 | -LRB- | denotes | ( |
T13779 | 1590-1591 | FW | denotes | n |
T13780 | 1592-1593 | SYM | denotes | = |
T13781 | 1594-1596 | CD | denotes | 15 |
T13782 | 1597-1599 | CD | denotes | 19 |
T13783 | 1599-1600 | -RRB- | denotes | ) |
T13784 | 1601-1605 | VBD | denotes | were |
T13785 | 1606-1612 | VBN | denotes | primed |
T13786 | 1613-1617 | IN | denotes | with |
T13787 | 1618-1621 | NNP | denotes | LPS |
T13788 | 1622-1623 | -LRB- | denotes | ( |
T13789 | 1623-1625 | CD | denotes | 10 |
T13790 | 1626-1631 | NN | denotes | ng/ml |
T13791 | 1631-1632 | -RRB- | denotes | ) |
T13792 | 1633-1642 | JJ | denotes | overnight |
T13793 | 1643-1646 | CC | denotes | and |
T13794 | 1647-1657 | VBN | denotes | stimulated |
T13795 | 1658-1662 | IN | denotes | with |
T13796 | 1663-1665 | NNP | denotes | P. |
T13797 | 1666-1676 | NN | denotes | aeruginosa |
T13798 | 1677-1681 | NNP | denotes | PAO1 |
T13799 | 1682-1683 | -LRB- | denotes | ( |
T13800 | 1683-1686 | NNP | denotes | MOI |
T13801 | 1687-1688 | SYM | denotes | = |
T13802 | 1689-1690 | LS | denotes | 1 |
T13803 | 1690-1691 | -RRB- | denotes | ) |
T13804 | 1691-1692 | , | denotes | , |
T13805 | 1693-1695 | NNP | denotes | P. |
T13806 | 1696-1706 | NNP | denotes | aeruginosa |
T13807 | 1707-1711 | NNP | denotes | PAO1 |
T13808 | 1712-1719 | VBG | denotes | lacking |
T13809 | 1720-1724 | NNP | denotes | exsA |
T13810 | 1725-1726 | -LRB- | denotes | ( |
T13811 | 1726-1729 | NNP | denotes | MOI |
T13812 | 1730-1731 | SYM | denotes | = |
T13813 | 1732-1733 | LS | denotes | 1 |
T13814 | 1733-1734 | -RRB- | denotes | ) |
T13815 | 1734-1735 | , | denotes | , |
T13816 | 1736-1739 | NNP | denotes | ATP |
T13817 | 1740-1741 | -LRB- | denotes | ( |
T13818 | 1741-1742 | CD | denotes | 5 |
T13819 | 1743-1745 | NNP | denotes | mM |
T13820 | 1745-1746 | -RRB- | denotes | ) |
T13821 | 1746-1747 | , | denotes | , |
T13822 | 1748-1750 | CC | denotes | or |
T13823 | 1751-1755 | NNP | denotes | Poly |
T13824 | 1755-1756 | -LRB- | denotes | ( |
T13825 | 1756-1758 | NNP | denotes | dA |
T13826 | 1758-1759 | : | denotes | : |
T13827 | 1759-1761 | NN | denotes | dT |
T13828 | 1761-1762 | -RRB- | denotes | ) |
T13829 | 1763-1764 | -LRB- | denotes | ( |
T13830 | 1764-1765 | CD | denotes | 1 |
T13831 | 1766-1768 | NN | denotes | µg |
T13832 | 1768-1769 | NN | denotes | / |
T13833 | 1769-1771 | NN | denotes | ml |
T13834 | 1771-1772 | -RRB- | denotes | ) |
T13835 | 1773-1776 | IN | denotes | for |
T13836 | 1777-1779 | CD | denotes | 24 |
T13837 | 1780-1785 | NNS | denotes | hours |
T13838 | 1785-1786 | . | denotes | . |
T13839 | 1787-1789 | NNP | denotes | P. |
T13840 | 1790-1800 | NN | denotes | aeruginosa |
T13841 | 1801-1808 | VBG | denotes | lacking |
T13842 | 1809-1813 | NNP | denotes | exsA |
T13843 | 1814-1817 | VBD | denotes | was |
T13844 | 1818-1822 | VBN | denotes | used |
T13845 | 1823-1825 | IN | denotes | as |
T13846 | 1826-1827 | DT | denotes | a |
T13847 | 1828-1832 | NN | denotes | type |
T13848 | 1833-1836 | NNP | denotes | III |
T13849 | 1837-1846 | NN | denotes | secretion |
T13850 | 1847-1854 | NN | denotes | control |
T13851 | 1855-1857 | IN | denotes | in |
T13852 | 1858-1868 | NN | denotes | comparison |
T13853 | 1869-1873 | IN | denotes | with |
T13854 | 1874-1883 | JJ | denotes | wild-type |
T13855 | 1884-1886 | NNP | denotes | P. |
T13856 | 1887-1897 | NN | denotes | aeruginosa |
T13857 | 1897-1898 | . | denotes | . |
T13858 | 1899-1911 | NNS | denotes | Supernatants |
T13859 | 1912-1916 | VBD | denotes | were |
T13860 | 1917-1924 | VBN | denotes | assayed |
T13861 | 1925-1928 | IN | denotes | for |
T13862 | 1929-1930 | -LRB- | denotes | ( |
T13863 | 1930-1931 | NN | denotes | A |
T13864 | 1931-1932 | -RRB- | denotes | ) |
T13865 | 1933-1938 | NN | denotes | IL-1β |
T13866 | 1939-1942 | CC | denotes | and |
T13867 | 1943-1944 | -LRB- | denotes | ( |
T13868 | 1944-1945 | NNP | denotes | B |
T13869 | 1945-1946 | -RRB- | denotes | ) |
T13870 | 1947-1951 | NN | denotes | IL-8 |
T13871 | 1951-1952 | . | denotes | . |
R3404 | T3916 | T3922 | nsubj | PBMCs,produce |
R3405 | T3917 | T3916 | prep | from,PBMCs |
R3406 | T3918 | T3919 | compound | CF,patients |
R3407 | T3919 | T3917 | pobj | patients,from |
R3408 | T3920 | T3922 | aux | do,produce |
R3409 | T3921 | T3922 | neg | not,produce |
R3410 | T3922 | T3922 | ROOT | produce,produce |
R3411 | T3923 | T3924 | amod | increased,amounts |
R3412 | T3924 | T3922 | dobj | amounts,produce |
R3413 | T3925 | T3924 | prep | of,amounts |
R3414 | T3926 | T3925 | pobj | IL-1β,of |
R3415 | T3927 | T3922 | prep | upon,produce |
R3416 | T3928 | T3929 | amod | inflammasome,stimulation |
R3417 | T3929 | T3931 | nmod | stimulation,studies |
R3418 | T3930 | T3931 | amod | Previous,studies |
R3419 | T3931 | T3927 | pobj | studies,upon |
R3420 | T3932 | T3933 | aux | have,shown |
R3421 | T3933 | T3922 | conj | shown,produce |
R3422 | T3934 | T3933 | dobj | that,shown |
R3423 | T3935 | T3936 | det | the,loss |
R3424 | T3936 | T3934 | nsubj | loss,that |
R3425 | T3937 | T3936 | prep | of,loss |
R3426 | T3938 | T3939 | compound | CFTR,results |
R3427 | T3939 | T3937 | pobj | results,of |
R3428 | T3940 | T3939 | prep | in,results |
R3429 | T3941 | T3943 | amod | increased,activity |
R3430 | T3942 | T3943 | compound | NF-κB,activity |
R3431 | T3943 | T3940 | pobj | activity,in |
R3432 | T3944 | T3943 | cc | and,activity |
R3433 | T3945 | T3947 | amod | pro-inflammatory,secretion |
R3434 | T3946 | T3947 | compound | cytokine,secretion |
R3435 | T3947 | T3943 | conj | secretion,activity |
R3436 | T3948 | T3950 | nmod | [,] |
R3437 | T3949 | T3950 | nummod | 4,] |
R3438 | T3950 | T3947 | nmod | ],secretion |
R3439 | T3951 | T3950 | punct | ",",] |
R3440 | T3952 | T3954 | nmod | [,] |
R3441 | T3953 | T3954 | nummod | 5,] |
R3442 | T3954 | T3950 | conj | ],] |
R3443 | T3955 | T3954 | punct | ",",] |
R3444 | T3956 | T3958 | nmod | [,] |
R3445 | T3957 | T3958 | nummod | 32,] |
R3446 | T3958 | T3954 | conj | ],] |
R3447 | T3959 | T3958 | punct | ",",] |
R3448 | T3960 | T3958 | conj | [,] |
R3449 | T3961 | T3962 | nummod | 36,] |
R3450 | T3962 | T3958 | conj | ],] |
R3451 | T3963 | T3962 | punct | ",",] |
R3452 | T3964 | T3962 | conj | [,] |
R3453 | T3965 | T3966 | nummod | 37,] |
R3454 | T3966 | T3962 | conj | ],] |
R3455 | T3967 | T3922 | punct | .,produce |
R3456 | T3968 | T3970 | aux | To,examine |
R3457 | T3969 | T3970 | advmod | further,examine |
R3458 | T3970 | T3983 | advcl | examine,stimulated |
R3459 | T3971 | T3972 | det | this,relationship |
R3460 | T3972 | T3970 | dobj | relationship,examine |
R3461 | T3973 | T3983 | punct | ",",stimulated |
R3462 | T3974 | T3983 | nsubjpass | PBMCs,stimulated |
R3463 | T3975 | T3974 | prep | from,PBMCs |
R3464 | T3976 | T3977 | compound | CF,patients |
R3465 | T3977 | T3975 | pobj | patients,from |
R3466 | T3978 | T3977 | cc | and,patients |
R3467 | T3979 | T3981 | amod | healthy,controls |
R3468 | T3980 | T3981 | compound | adult,controls |
R3469 | T3981 | T3977 | conj | controls,patients |
R3470 | T3982 | T3983 | auxpass | were,stimulated |
R3471 | T3983 | T3983 | ROOT | stimulated,stimulated |
R3472 | T3984 | T3983 | prep | with,stimulated |
R3473 | T3985 | T3984 | pobj | PAO1,with |
R3474 | T3986 | T3985 | punct | ",",PAO1 |
R3475 | T3987 | T3985 | conj | LPS+ATP,PAO1 |
R3476 | T3988 | T3987 | punct | ",",LPS+ATP |
R3477 | T3989 | T3987 | cc | and,LPS+ATP |
R3478 | T3990 | T3991 | compound | LPS+P,oly |
R3479 | T3991 | T3987 | conj | oly,LPS+ATP |
R3480 | T3992 | T3995 | punct | (,dT |
R3481 | T3993 | T3995 | nmod | dA,dT |
R3482 | T3994 | T3995 | punct | :,dT |
R3483 | T3995 | T3991 | appos | dT,oly |
R3484 | T3996 | T3995 | punct | ),dT |
R3485 | T3997 | T3983 | punct | ",",stimulated |
R3486 | T3998 | T3999 | aux | to,activate |
R3487 | T3999 | T3983 | advcl | activate,stimulated |
R3488 | T4000 | T4001 | det | the,NLRC4 |
R3489 | T4001 | T3999 | dobj | NLRC4,activate |
R3490 | T4002 | T4001 | punct | ",",NLRC4 |
R3491 | T4003 | T4001 | conj | NLRP3,NLRC4 |
R3492 | T4004 | T4003 | punct | ",",NLRP3 |
R3493 | T4005 | T4003 | cc | and,NLRP3 |
R3494 | T4006 | T4003 | conj | AIM2,NLRP3 |
R3495 | T4007 | T4001 | appos | inflammasomes,NLRC4 |
R3496 | T4008 | T4007 | punct | ",",inflammasomes |
R3497 | T4009 | T4007 | advmod | respectively,inflammasomes |
R3498 | T4010 | T3983 | punct | .,stimulated |
R3499 | T4011 | T4021 | prep | By,produce |
R3500 | T4012 | T4013 | nummod | 24,hours |
R3501 | T4013 | T4011 | pobj | hours,By |
R3502 | T4014 | T4013 | prep | of,hours |
R3503 | T4015 | T4014 | pobj | stimulation,of |
R3504 | T4016 | T4021 | punct | ",",produce |
R3505 | T4017 | T4018 | compound | CF,PBMCs |
R3506 | T4018 | T4021 | nsubj | PBMCs,produce |
R3507 | T4019 | T4021 | aux | did,produce |
R3508 | T4020 | T4021 | neg | not,produce |
R3509 | T4021 | T4021 | ROOT | produce,produce |
R3510 | T4022 | T4023 | amod | increased,amounts |
R3511 | T4023 | T4021 | dobj | amounts,produce |
R3512 | T4024 | T4023 | prep | of,amounts |
R3513 | T4025 | T4024 | pobj | IL-1β,of |
R3514 | T4026 | T4023 | punct | (,amounts |
R3515 | T4027 | T4023 | appos | Fig.,amounts |
R3516 | T4028 | T4027 | nummod | 5a,Fig. |
R3517 | T4029 | T4027 | punct | ),Fig. |
R3518 | T4030 | T4027 | cc | or,Fig. |
R3519 | T4031 | T4027 | conj | IL-8,Fig. |
R3520 | T4032 | T4033 | punct | (,Fig. |
R3521 | T4033 | T4031 | appos | Fig.,IL-8 |
R3522 | T4034 | T4033 | nummod | 5b,Fig. |
R3523 | T4035 | T4031 | punct | ),IL-8 |
R3524 | T4036 | T4037 | advmod | when,compared |
R3525 | T4037 | T4021 | advcl | compared,produce |
R3526 | T4038 | T4037 | prep | to,compared |
R3527 | T4039 | T4040 | amod | healthy,controls |
R3528 | T4040 | T4038 | pobj | controls,to |
R3529 | T4041 | T4021 | punct | .,produce |
R3530 | T4042 | T4046 | advmod | However,notice |
R3531 | T4043 | T4046 | punct | ",",notice |
R3532 | T4044 | T4046 | nsubj | we,notice |
R3533 | T4045 | T4046 | aux | did,notice |
R3534 | T4046 | T4046 | ROOT | notice,notice |
R3535 | T4047 | T4049 | det | a,decrease |
R3536 | T4048 | T4049 | amod | transient,decrease |
R3537 | T4049 | T4046 | dobj | decrease,notice |
R3538 | T4050 | T4051 | punct | (,P |
R3539 | T4051 | T4049 | appos | P,decrease |
R3540 | T4052 | T4051 | nummod | <,P |
R3541 | T4053 | T4051 | nummod | 0.001,P |
R3542 | T4054 | T4051 | punct | ),P |
R3543 | T4055 | T4049 | prep | in,decrease |
R3544 | T4056 | T4057 | det | the,amount |
R3545 | T4057 | T4055 | pobj | amount,in |
R3546 | T4058 | T4057 | prep | of,amount |
R3547 | T4059 | T4074 | dobj | IL-1β,shown |
R3548 | T4060 | T4059 | acl | produced,IL-1β |
R3549 | T4061 | T4060 | agent | by,produced |
R3550 | T4062 | T4063 | compound | CF,cells |
R3551 | T4063 | T4061 | pobj | cells,by |
R3552 | T4064 | T4060 | prep | in,produced |
R3553 | T4065 | T4064 | pobj | response,in |
R3554 | T4066 | T4065 | prep | to,response |
R3555 | T4067 | T4066 | pobj | LPS+ATP,to |
R3556 | T4068 | T4065 | prep | at,response |
R3557 | T4069 | T4070 | nummod | 6,hours |
R3558 | T4070 | T4068 | pobj | hours,at |
R3559 | T4071 | T4074 | punct | (,shown |
R3560 | T4072 | T4074 | nsubj | data,shown |
R3561 | T4073 | T4074 | neg | not,shown |
R3562 | T4074 | T4049 | relcl | shown,decrease |
R3563 | T4075 | T4049 | punct | ),decrease |
R3564 | T4076 | T4046 | punct | .,notice |
R3565 | T4077 | T4098 | nsubj | Stimulation,produced |
R3566 | T4078 | T4077 | prep | of,Stimulation |
R3567 | T4079 | T4078 | pobj | PBMCs,of |
R3568 | T4080 | T4079 | prep | with,PBMCs |
R3569 | T4081 | T4082 | compound | P.,aeruginosa |
R3570 | T4082 | T4080 | pobj | aeruginosa,with |
R3571 | T4083 | T4084 | nsubj | that,lacks |
R3572 | T4084 | T4082 | relcl | lacks,aeruginosa |
R3573 | T4085 | T4084 | dobj | exsA,lacks |
R3574 | T4086 | T4087 | punct | (,PAO1ΔexsA |
R3575 | T4087 | T4085 | appos | PAO1ΔexsA,exsA |
R3576 | T4088 | T4077 | punct | ),Stimulation |
R3577 | T4089 | T4077 | punct | ",",Stimulation |
R3578 | T4090 | T4092 | det | a,regulator |
R3579 | T4091 | T4092 | amod | key,regulator |
R3580 | T4092 | T4077 | appos | regulator,Stimulation |
R3581 | T4093 | T4092 | prep | of,regulator |
R3582 | T4094 | T4096 | compound | type,secretion |
R3583 | T4095 | T4096 | compound | III,secretion |
R3584 | T4096 | T4093 | pobj | secretion,of |
R3585 | T4097 | T4098 | punct | ",",produced |
R3586 | T4098 | T4098 | ROOT | produced,produced |
R3587 | T4099 | T4101 | amod | three-fold,IL-1β |
R3588 | T4100 | T4101 | advmod | less,IL-1β |
R3589 | T4101 | T4102 | amod | IL-1β,compared |
R3590 | T4102 | T4098 | prep | compared,produced |
R3591 | T4103 | T4102 | prep | to,compared |
R3592 | T4104 | T4107 | det | the,strain |
R3593 | T4105 | T4107 | amod | parental,strain |
R3594 | T4106 | T4107 | compound | PAO1,strain |
R3595 | T4107 | T4103 | pobj | strain,to |
R3596 | T4108 | T4107 | prep | by,strain |
R3597 | T4109 | T4110 | nummod | 24,hours |
R3598 | T4110 | T4108 | pobj | hours,by |
R3599 | T4111 | T4110 | punct | (,hours |
R3600 | T4112 | T4110 | appos | Fig.,hours |
R3601 | T4113 | T4112 | nummod | 5a,Fig. |
R3602 | T4114 | T4110 | punct | ),hours |
R3603 | T4115 | T4098 | punct | .,produced |
R3604 | T4116 | T4117 | amod | Inflammasome,stimulation |
R3605 | T4117 | T4122 | nsubj | stimulation,result |
R3606 | T4118 | T4117 | prep | without,stimulation |
R3607 | T4119 | T4118 | pcomp | priming,without |
R3608 | T4120 | T4122 | aux | did,result |
R3609 | T4121 | T4122 | neg | not,result |
R3610 | T4122 | T4122 | ROOT | result,result |
R3611 | T4123 | T4122 | prep | in,result |
R3612 | T4124 | T4126 | det | any,production |
R3613 | T4125 | T4126 | amod | IL-1β,production |
R3614 | T4126 | T4123 | pobj | production,in |
R3615 | T4127 | T4126 | prep | in,production |
R3616 | T4128 | T4129 | det | either,CF |
R3617 | T4129 | T4127 | pobj | CF,in |
R3618 | T4130 | T4129 | cc | or,CF |
R3619 | T4131 | T4132 | compound | control,PBMCs |
R3620 | T4132 | T4129 | conj | PBMCs,CF |
R3621 | T4133 | T4122 | punct | .,result |
R3622 | T4134 | T4141 | advcl | Contrary,indicate |
R3623 | T4135 | T4134 | prep | to,Contrary |
R3624 | T4136 | T4137 | poss | our,hypothesis |
R3625 | T4137 | T4135 | pobj | hypothesis,to |
R3626 | T4138 | T4141 | punct | ",",indicate |
R3627 | T4139 | T4140 | det | these,results |
R3628 | T4140 | T4141 | nsubj | results,indicate |
R3629 | T4141 | T4141 | ROOT | indicate,indicate |
R3630 | T4142 | T4149 | mark | that,display |
R3631 | T4143 | T4149 | nsubj | PBMCs,display |
R3632 | T4144 | T4143 | prep | from,PBMCs |
R3633 | T4145 | T4146 | compound | CF,patients |
R3634 | T4146 | T4144 | pobj | patients,from |
R3635 | T4147 | T4149 | aux | do,display |
R3636 | T4148 | T4149 | neg | not,display |
R3637 | T4149 | T4141 | ccomp | display,indicate |
R3638 | T4150 | T4151 | amod | increased,production |
R3639 | T4151 | T4149 | dobj | production,display |
R3640 | T4152 | T4151 | prep | of,production |
R3641 | T4153 | T4152 | pobj | IL-1β,of |
R3642 | T4154 | T4153 | cc | or,IL-1β |
R3643 | T4155 | T4153 | conj | IL-8,IL-1β |
R3644 | T4156 | T4149 | prep | with,display |
R3645 | T4157 | T4158 | amod | inflammasome,activation |
R3646 | T4158 | T4156 | pobj | activation,with |
R3647 | T4159 | T4149 | cc | nor,display |
R3648 | T4160 | T4162 | aux | do,suggest |
R3649 | T4161 | T4162 | nsubj | they,suggest |
R3650 | T4162 | T4149 | conj | suggest,display |
R3651 | T4163 | T4165 | det | any,basal |
R3652 | T4164 | T4165 | amod | increased,basal |
R3653 | T4165 | T4162 | dobj | basal,suggest |
R3654 | T4166 | T4165 | cc | or,basal |
R3655 | T4167 | T4169 | amod | induced,activity |
R3656 | T4168 | T4169 | compound | NF-κB,activity |
R3657 | T4169 | T4165 | conj | activity,basal |
R3658 | T4170 | T4141 | punct | .,indicate |
R3659 | T4171 | T4172 | det | These,results |
R3660 | T4172 | T4173 | nsubj | results,are |
R3661 | T4173 | T4173 | ROOT | are,are |
R3662 | T4174 | T4173 | acomp | consistent,are |
R3663 | T4175 | T4174 | prep | with,consistent |
R3664 | T4176 | T4177 | poss | our,observation |
R3665 | T4177 | T4175 | pobj | observation,with |
R3666 | T4178 | T4181 | mark | that,is |
R3667 | T4179 | T4180 | amod | caspase-1,activity |
R3668 | T4180 | T4181 | nsubj | activity,is |
R3669 | T4181 | T4173 | advcl | is,are |
R3670 | T4182 | T4181 | neg | not,is |
R3671 | T4183 | T4181 | acomp | different,is |
R3672 | T4184 | T4183 | prep | between,different |
R3673 | T4185 | T4184 | pobj | CF,between |
R3674 | T4186 | T4185 | cc | and,CF |
R3675 | T4187 | T4188 | compound | control,PBMCs |
R3676 | T4188 | T4185 | conj | PBMCs,CF |
R3677 | T4189 | T4190 | punct | (,Fig. |
R3678 | T4190 | T4188 | appos | Fig.,PBMCs |
R3679 | T4191 | T4190 | nummod | 4,Fig. |
R3680 | T4192 | T4188 | punct | ),PBMCs |
R3681 | T4193 | T4173 | punct | .,are |
R12214 | T13759 | T13759 | ROOT | produce,produce |
R12208 | T13753 | T13759 | nsubj | PBMCs,produce |
R12209 | T13754 | T13753 | prep | from,PBMCs |
R12210 | T13755 | T13756 | compound | CF,patients |
R12211 | T13756 | T13754 | pobj | patients,from |
R12212 | T13757 | T13759 | aux | do,produce |
R12213 | T13758 | T13759 | neg | not,produce |
R12215 | T13760 | T13761 | amod | increased,amounts |
R12216 | T13761 | T13759 | dobj | amounts,produce |
R12217 | T13762 | T13761 | prep | of,amounts |
R12218 | T13763 | T13762 | pobj | IL-1β,of |
R12219 | T13764 | T13759 | punct | .,produce |
R12220 | T13765 | T13770 | nsubj | PBMCs,n |
R12221 | T13766 | T13765 | prep | from,PBMCs |
R12222 | T13767 | T13768 | compound | CF,patients |
R12223 | T13768 | T13766 | pobj | patients,from |
R12224 | T13769 | T13768 | punct | (,patients |
R12225 | T13770 | T13770 | ROOT | n,n |
R12226 | T13771 | T13772 | punct | =,17 |
R12227 | T13772 | T13770 | nummod | 17,n |
R12228 | T13773 | T13772 | appos | 20,17 |
R12229 | T13774 | T13772 | punct | ),17 |
R12230 | T13775 | T13770 | cc | and,n |
R12231 | T13776 | T13777 | amod | healthy,controls |
R12232 | T13777 | T13770 | conj | controls,n |
R12233 | T13778 | T13777 | punct | (,controls |
R12234 | T13779 | T13785 | nsubjpass | n,primed |
R12235 | T13780 | T13781 | punct | =,15 |
R12236 | T13781 | T13779 | prep | 15,n |
R12237 | T13782 | T13781 | appos | 19,15 |
R12238 | T13783 | T13781 | punct | ),15 |
R12239 | T13784 | T13785 | auxpass | were,primed |
R12240 | T13785 | T13785 | ROOT | primed,primed |
R12241 | T13786 | T13785 | prep | with,primed |
R12242 | T13787 | T13786 | pobj | LPS,with |
R12243 | T13788 | T13787 | punct | (,LPS |
R12244 | T13789 | T13790 | nummod | 10,ng/ml |
R12245 | T13790 | T13787 | appos | ng/ml,LPS |
R12246 | T13791 | T13790 | punct | ),ng/ml |
R12247 | T13792 | T13787 | conj | overnight,LPS |
R12248 | T13793 | T13792 | cc | and,overnight |
R12249 | T13794 | T13792 | conj | stimulated,overnight |
R12250 | T13795 | T13794 | prep | with,stimulated |
R12251 | T13796 | T13798 | compound | P.,PAO1 |
R12252 | T13797 | T13798 | compound | aeruginosa,PAO1 |
R12253 | T13798 | T13795 | pobj | PAO1,with |
R12254 | T13799 | T13808 | punct | (,lacking |
R12255 | T13800 | T13808 | nsubj | MOI,lacking |
R12256 | T13801 | T13802 | punct | =,1 |
R12257 | T13802 | T13800 | nummod | 1,MOI |
R12258 | T13803 | T13802 | punct | ),1 |
R12259 | T13804 | T13800 | punct | ",",MOI |
R12260 | T13805 | T13807 | compound | P.,PAO1 |
R12261 | T13806 | T13807 | compound | aeruginosa,PAO1 |
R12262 | T13807 | T13808 | nsubj | PAO1,lacking |
R12263 | T13808 | T13808 | ROOT | lacking,lacking |
R12264 | T13809 | T13808 | dobj | exsA,lacking |
R12265 | T13810 | T13819 | punct | (,mM |
R12266 | T13811 | T13819 | nmod | MOI,mM |
R12267 | T13812 | T13813 | punct | =,1 |
R12268 | T13813 | T13811 | nummod | 1,MOI |
R12269 | T13814 | T13813 | punct | ),1 |
R12270 | T13815 | T13811 | punct | ",",MOI |
R12271 | T13816 | T13811 | conj | ATP,MOI |
R12272 | T13817 | T13818 | punct | (,5 |
R12273 | T13818 | T13819 | nummod | 5,mM |
R12274 | T13819 | T13809 | appos | mM,exsA |
R12275 | T13820 | T13819 | punct | ),mM |
R12276 | T13821 | T13809 | punct | ",",exsA |
R12277 | T13822 | T13809 | cc | or,exsA |
R12278 | T13823 | T13809 | conj | Poly,exsA |
R12279 | T13824 | T13823 | punct | (,Poly |
R12280 | T13825 | T13833 | nmod | dA,ml |
R12281 | T13826 | T13825 | punct | :,dA |
R12282 | T13827 | T13825 | appos | dT,dA |
R12283 | T13828 | T13825 | punct | ),dA |
R12284 | T13829 | T13833 | punct | (,ml |
R12285 | T13830 | T13831 | nummod | 1,µg |
R12286 | T13831 | T13833 | nmod | µg,ml |
R12287 | T13832 | T13833 | compound | /,ml |
R12288 | T13833 | T13823 | appos | ml,Poly |
R12289 | T13834 | T13823 | punct | ),Poly |
R12290 | T13835 | T13808 | prep | for,lacking |
R12291 | T13836 | T13837 | nummod | 24,hours |
R12292 | T13837 | T13835 | pobj | hours,for |
R12293 | T13838 | T13808 | punct | .,lacking |
R12294 | T13839 | T13840 | compound | P.,aeruginosa |
R12295 | T13840 | T13844 | nsubjpass | aeruginosa,used |
R12296 | T13841 | T13840 | acl | lacking,aeruginosa |
R12297 | T13842 | T13841 | dobj | exsA,lacking |
R12298 | T13843 | T13844 | auxpass | was,used |
R12299 | T13844 | T13844 | ROOT | used,used |
R12300 | T13845 | T13844 | prep | as,used |
R12301 | T13846 | T13850 | det | a,control |
R12302 | T13847 | T13850 | compound | type,control |
R12303 | T13848 | T13850 | compound | III,control |
R12304 | T13849 | T13850 | compound | secretion,control |
R12305 | T13850 | T13845 | pobj | control,as |
R12306 | T13851 | T13850 | prep | in,control |
R12307 | T13852 | T13851 | pobj | comparison,in |
R12308 | T13853 | T13852 | prep | with,comparison |
R12309 | T13854 | T13856 | amod | wild-type,aeruginosa |
R12310 | T13855 | T13856 | compound | P.,aeruginosa |
R12311 | T13856 | T13853 | pobj | aeruginosa,with |
R12312 | T13857 | T13844 | punct | .,used |
R12313 | T13858 | T13860 | nsubjpass | Supernatants,assayed |
R12314 | T13859 | T13860 | auxpass | were,assayed |
R12315 | T13860 | T13860 | ROOT | assayed,assayed |
R12316 | T13861 | T13860 | prep | for,assayed |
R12317 | T13862 | T13863 | punct | (,A |
R12318 | T13863 | T13861 | pobj | A,for |
R12319 | T13864 | T13863 | punct | ),A |
R12320 | T13865 | T13860 | advcl | IL-1β,assayed |
R12321 | T13866 | T13865 | cc | and,IL-1β |
R12322 | T13867 | T13868 | punct | (,B |
R12323 | T13868 | T13865 | conj | B,IL-1β |
R12324 | T13869 | T13868 | punct | ),B |
R12325 | T13870 | T13865 | conj | IL-8,IL-1β |
R12326 | T13871 | T13860 | punct | .,assayed |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3638 | 0-5 | NN | denotes | PBMCs |
T3639 | 6-10 | IN | denotes | from |
T3640 | 11-13 | NN | denotes | CF |
T3641 | 14-22 | NN | denotes | patients |
T3642 | 23-25 | VB | denotes | do |
T3643 | 26-29 | RB | denotes | not |
T3644 | 30-37 | VB | denotes | produce |
T3645 | 38-47 | VB | denotes | increased |
T3646 | 48-55 | NN | denotes | amounts |
T3647 | 56-58 | IN | denotes | of |
T3648 | 59-64 | NN | denotes | IL-1β |
T3649 | 65-69 | IN | denotes | upon |
T3650 | 70-82 | JJ | denotes | inflammasome |
T3651 | 83-94 | NN | denotes | stimulation |
T3652 | 95-103 | JJ | denotes | Previous |
T3653 | 104-111 | NN | denotes | studies |
T3654 | 112-116 | VB | denotes | have |
T3655 | 117-122 | VB | denotes | shown |
T3656 | 123-127 | IN | denotes | that |
T3657 | 128-131 | DT | denotes | the |
T3658 | 132-136 | NN | denotes | loss |
T3659 | 137-139 | IN | denotes | of |
T3660 | 140-144 | NN | denotes | CFTR |
T3661 | 145-152 | VB | denotes | results |
T3662 | 153-155 | IN | denotes | in |
T3663 | 156-165 | VB | denotes | increased |
T3664 | 166-171 | NN | denotes | NF-κB |
T3665 | 172-180 | NN | denotes | activity |
T3666 | 181-184 | CC | denotes | and |
T3667 | 185-201 | JJ | denotes | pro-inflammatory |
T3668 | 202-210 | NN | denotes | cytokine |
T3669 | 211-220 | NN | denotes | secretion |
T3670 | 221-222 | -LRB- | denotes | [ |
T3671 | 222-223 | CD | denotes | 4 |
T3672 | 223-224 | -RRB- | denotes | ] |
T3673 | 224-225 | -COMMA- | denotes | , |
T3674 | 226-227 | -LRB- | denotes | [ |
T3675 | 227-228 | CD | denotes | 5 |
T3676 | 228-229 | -RRB- | denotes | ] |
T3677 | 229-230 | -COMMA- | denotes | , |
T3678 | 231-232 | -LRB- | denotes | [ |
T3679 | 232-234 | CD | denotes | 32 |
T3680 | 234-235 | -RRB- | denotes | ] |
T3681 | 235-236 | -COMMA- | denotes | , |
T3682 | 237-238 | -LRB- | denotes | [ |
T3683 | 238-240 | CD | denotes | 36 |
T3684 | 240-241 | -RRB- | denotes | ] |
T3685 | 241-242 | -COMMA- | denotes | , |
T3686 | 243-244 | -LRB- | denotes | [ |
T3687 | 244-246 | CD | denotes | 37 |
T3688 | 246-247 | -RRB- | denotes | ] |
T3689 | 249-251 | TO | denotes | To |
T3690 | 252-259 | RB | denotes | further |
T3691 | 260-267 | VB | denotes | examine |
T3692 | 268-272 | DT | denotes | this |
T3693 | 273-285 | NN | denotes | relationship |
T3694 | 285-286 | -COMMA- | denotes | , |
T3695 | 287-292 | NN | denotes | PBMCs |
T3696 | 293-297 | IN | denotes | from |
T3697 | 298-300 | NN | denotes | CF |
T3698 | 301-309 | NN | denotes | patients |
T3699 | 310-313 | CC | denotes | and |
T3700 | 314-321 | JJ | denotes | healthy |
T3701 | 322-327 | JJ | denotes | adult |
T3702 | 328-336 | NN | denotes | controls |
T3703 | 337-341 | VB | denotes | were |
T3704 | 342-352 | VB | denotes | stimulated |
T3705 | 353-357 | IN | denotes | with |
T3706 | 358-362 | NN | denotes | PAO1 |
T3707 | 362-363 | -COMMA- | denotes | , |
T3708 | 364-371 | NN | denotes | LPS+ATP |
T3709 | 371-372 | -COMMA- | denotes | , |
T3710 | 373-376 | CC | denotes | and |
T3711 | 377-385 | NN | denotes | LPS+Poly |
T3712 | 385-386 | -LRB- | denotes | ( |
T3713 | 386-388 | NN | denotes | dA |
T3714 | 388-389 | -COLON- | denotes | : |
T3715 | 389-391 | NN | denotes | dT |
T3716 | 391-392 | -RRB- | denotes | ) |
T3717 | 392-393 | -COMMA- | denotes | , |
T3718 | 394-396 | TO | denotes | to |
T3719 | 397-405 | VB | denotes | activate |
T3720 | 406-409 | DT | denotes | the |
T3721 | 410-415 | NN | denotes | NLRC4 |
T3722 | 415-416 | -COMMA- | denotes | , |
T3723 | 417-422 | NN | denotes | NLRP3 |
T3724 | 422-423 | -COMMA- | denotes | , |
T3725 | 424-427 | CC | denotes | and |
T3726 | 428-432 | NN | denotes | AIM2 |
T3727 | 433-446 | NN | denotes | inflammasomes |
T3728 | 446-447 | -COMMA- | denotes | , |
T3729 | 448-460 | RB | denotes | respectively |
T3730 | 462-464 | IN | denotes | By |
T3731 | 465-467 | CD | denotes | 24 |
T3732 | 468-473 | NN | denotes | hours |
T3733 | 474-476 | IN | denotes | of |
T3734 | 477-488 | NN | denotes | stimulation |
T3735 | 488-489 | -COMMA- | denotes | , |
T3736 | 490-492 | NN | denotes | CF |
T3737 | 493-498 | NN | denotes | PBMCs |
T3738 | 499-502 | VB | denotes | did |
T3739 | 503-506 | RB | denotes | not |
T3740 | 507-514 | VB | denotes | produce |
T3741 | 515-524 | VB | denotes | increased |
T3742 | 525-532 | NN | denotes | amounts |
T3743 | 533-535 | IN | denotes | of |
T3744 | 536-541 | NN | denotes | IL-1β |
T3745 | 542-543 | -LRB- | denotes | ( |
T3746 | 543-547 | NN | denotes | Fig. |
T3747 | 548-550 | NN | denotes | 5a |
T3748 | 550-551 | -RRB- | denotes | ) |
T3749 | 552-554 | CC | denotes | or |
T3750 | 555-559 | NN | denotes | IL-8 |
T3751 | 560-561 | -LRB- | denotes | ( |
T3752 | 561-565 | NN | denotes | Fig. |
T3753 | 566-568 | NN | denotes | 5b |
T3754 | 568-569 | -RRB- | denotes | ) |
T3755 | 570-574 | WRB | denotes | when |
T3756 | 575-583 | VB | denotes | compared |
T3757 | 584-586 | TO | denotes | to |
T3758 | 587-594 | JJ | denotes | healthy |
T3759 | 595-603 | NN | denotes | controls |
T3760 | 605-612 | RB | denotes | However |
T3761 | 612-613 | -COMMA- | denotes | , |
T3762 | 614-616 | PRP | denotes | we |
T3763 | 617-620 | VB | denotes | did |
T3764 | 621-627 | VB | denotes | notice |
T3765 | 628-629 | DT | denotes | a |
T3766 | 630-639 | JJ | denotes | transient |
T3767 | 640-648 | NN | denotes | decrease |
T3768 | 649-650 | -LRB- | denotes | ( |
T3769 | 650-651 | NN | denotes | P |
T3770 | 651-652 | SYM | denotes | < |
T3771 | 652-657 | CD | denotes | 0.001 |
T3772 | 657-658 | -RRB- | denotes | ) |
T3773 | 659-661 | IN | denotes | in |
T3774 | 662-665 | DT | denotes | the |
T3775 | 666-672 | NN | denotes | amount |
T3776 | 673-675 | IN | denotes | of |
T3777 | 676-681 | NN | denotes | IL-1β |
T3778 | 682-690 | VB | denotes | produced |
T3779 | 691-693 | IN | denotes | by |
T3780 | 694-696 | NN | denotes | CF |
T3781 | 697-702 | NN | denotes | cells |
T3782 | 703-705 | IN | denotes | in |
T3783 | 706-714 | NN | denotes | response |
T3784 | 715-717 | TO | denotes | to |
T3785 | 718-725 | NN | denotes | LPS+ATP |
T3786 | 726-728 | IN | denotes | at |
T3787 | 729-730 | CD | denotes | 6 |
T3788 | 731-736 | NN | denotes | hours |
T3789 | 737-738 | -LRB- | denotes | ( |
T3790 | 738-742 | NN | denotes | data |
T3791 | 743-746 | RB | denotes | not |
T3792 | 747-752 | VB | denotes | shown |
T3793 | 752-753 | -RRB- | denotes | ) |
T3794 | 755-766 | NN | denotes | Stimulation |
T3795 | 767-769 | IN | denotes | of |
T3796 | 770-775 | NN | denotes | PBMCs |
T3797 | 776-780 | IN | denotes | with |
T3798 | 781-783 | NNP | denotes | P. |
T3799 | 784-794 | NN | denotes | aeruginosa |
T3800 | 795-799 | WDT | denotes | that |
T3801 | 800-805 | VB | denotes | lacks |
T3802 | 806-810 | NN | denotes | exsA |
T3803 | 811-812 | -LRB- | denotes | ( |
T3804 | 812-821 | NN | denotes | PAO1ΔexsA |
T3805 | 821-822 | -RRB- | denotes | ) |
T3806 | 822-823 | -COMMA- | denotes | , |
T3807 | 824-825 | DT | denotes | a |
T3808 | 826-829 | JJ | denotes | key |
T3809 | 830-839 | NN | denotes | regulator |
T3810 | 840-842 | IN | denotes | of |
T3811 | 843-847 | NN | denotes | type |
T3812 | 848-851 | CD | denotes | III |
T3813 | 852-861 | NN | denotes | secretion |
T3814 | 861-862 | -COMMA- | denotes | , |
T3815 | 863-871 | VB | denotes | produced |
T3816 | 872-882 | RB | denotes | three-fold |
T3817 | 883-887 | JJ | denotes | less |
T3818 | 888-893 | NN | denotes | IL-1β |
T3819 | 894-902 | VB | denotes | compared |
T3820 | 903-905 | TO | denotes | to |
T3821 | 906-909 | DT | denotes | the |
T3822 | 910-918 | JJ | denotes | parental |
T3823 | 919-923 | NN | denotes | PAO1 |
T3824 | 924-930 | NN | denotes | strain |
T3825 | 931-933 | IN | denotes | by |
T3826 | 934-936 | CD | denotes | 24 |
T3827 | 937-942 | NN | denotes | hours |
T3828 | 943-944 | -LRB- | denotes | ( |
T3829 | 944-948 | NNP | denotes | Fig. |
T3830 | 949-951 | NN | denotes | 5a |
T3831 | 951-952 | -RRB- | denotes | ) |
T3832 | 954-966 | JJ | denotes | Inflammasome |
T3833 | 967-978 | NN | denotes | stimulation |
T3834 | 979-986 | IN | denotes | without |
T3835 | 987-994 | NN | denotes | priming |
T3836 | 995-998 | VB | denotes | did |
T3837 | 999-1002 | RB | denotes | not |
T3838 | 1003-1009 | VB | denotes | result |
T3839 | 1010-1012 | IN | denotes | in |
T3840 | 1013-1016 | DT | denotes | any |
T3841 | 1017-1022 | NN | denotes | IL-1β |
T3842 | 1023-1033 | NN | denotes | production |
T3843 | 1034-1036 | IN | denotes | in |
T3844 | 1037-1043 | CC | denotes | either |
T3845 | 1044-1046 | NN | denotes | CF |
T3846 | 1047-1049 | CC | denotes | or |
T3847 | 1050-1057 | NN | denotes | control |
T3848 | 1058-1063 | NN | denotes | PBMCs |
T3849 | 1065-1073 | JJ | denotes | Contrary |
T3850 | 1074-1076 | TO | denotes | to |
T3851 | 1077-1080 | PRP-DOLLAR- | denotes | our |
T3852 | 1081-1091 | NN | denotes | hypothesis |
T3853 | 1091-1092 | -COMMA- | denotes | , |
T3854 | 1093-1098 | DT | denotes | these |
T3855 | 1099-1106 | NN | denotes | results |
T3856 | 1107-1115 | VB | denotes | indicate |
T3857 | 1116-1120 | IN | denotes | that |
T3858 | 1121-1126 | NN | denotes | PBMCs |
T3859 | 1127-1131 | IN | denotes | from |
T3860 | 1132-1134 | NN | denotes | CF |
T3861 | 1135-1143 | NN | denotes | patients |
T3862 | 1144-1146 | VB | denotes | do |
T3863 | 1147-1150 | RB | denotes | not |
T3864 | 1151-1158 | VB | denotes | display |
T3865 | 1159-1168 | VB | denotes | increased |
T3866 | 1169-1179 | NN | denotes | production |
T3867 | 1180-1182 | IN | denotes | of |
T3868 | 1183-1188 | NN | denotes | IL-1β |
T3869 | 1189-1191 | CC | denotes | or |
T3870 | 1192-1196 | NN | denotes | IL-8 |
T3871 | 1197-1201 | IN | denotes | with |
T3872 | 1202-1214 | JJ | denotes | inflammasome |
T3873 | 1215-1225 | NN | denotes | activation |
T3874 | 1226-1229 | CC | denotes | nor |
T3875 | 1230-1232 | VB | denotes | do |
T3876 | 1233-1237 | PRP | denotes | they |
T3877 | 1238-1245 | VB | denotes | suggest |
T3878 | 1246-1249 | DT | denotes | any |
T3879 | 1250-1259 | VB | denotes | increased |
T3880 | 1260-1265 | JJ | denotes | basal |
T3881 | 1266-1268 | CC | denotes | or |
T3882 | 1269-1276 | VB | denotes | induced |
T3883 | 1277-1282 | NN | denotes | NF-κB |
T3884 | 1283-1291 | NN | denotes | activity |
T3885 | 1293-1298 | DT | denotes | These |
T3886 | 1299-1306 | NN | denotes | results |
T3887 | 1307-1310 | VB | denotes | are |
T3888 | 1311-1321 | JJ | denotes | consistent |
T3889 | 1322-1326 | IN | denotes | with |
T3890 | 1327-1330 | PRP-DOLLAR- | denotes | our |
T3891 | 1331-1342 | NN | denotes | observation |
T3892 | 1343-1347 | IN | denotes | that |
T3893 | 1348-1357 | NN | denotes | caspase-1 |
T3894 | 1358-1366 | NN | denotes | activity |
T3895 | 1367-1369 | VB | denotes | is |
T3896 | 1370-1373 | RB | denotes | not |
T3897 | 1374-1383 | JJ | denotes | different |
T3898 | 1384-1391 | IN | denotes | between |
T3899 | 1392-1394 | NN | denotes | CF |
T3900 | 1395-1398 | CC | denotes | and |
T3901 | 1399-1406 | NN | denotes | control |
T3902 | 1407-1412 | NN | denotes | PBMCs |
T3903 | 1413-1414 | -LRB- | denotes | ( |
T3904 | 1414-1418 | NN | denotes | Fig. |
T3905 | 1419-1420 | CD | denotes | 4 |
T3906 | 1420-1421 | -RRB- | denotes | ) |
T13645 | 1467-1472 | NN | denotes | PBMCs |
T13646 | 1473-1477 | IN | denotes | from |
T13647 | 1478-1480 | NN | denotes | CF |
T13648 | 1481-1489 | NN | denotes | patients |
T13649 | 1490-1492 | VB | denotes | do |
T13650 | 1493-1496 | RB | denotes | not |
T13651 | 1497-1504 | VB | denotes | produce |
T13652 | 1505-1514 | VB | denotes | increased |
T13653 | 1515-1522 | NN | denotes | amounts |
T13654 | 1523-1525 | IN | denotes | of |
T13655 | 1526-1531 | NN | denotes | IL-1β |
T13656 | 1533-1538 | NN | denotes | PBMCs |
T13657 | 1539-1543 | IN | denotes | from |
T13658 | 1544-1546 | NN | denotes | CF |
T13659 | 1547-1555 | NN | denotes | patients |
T13660 | 1556-1557 | -LRB- | denotes | ( |
T13661 | 1557-1566 | NN | denotes | n = 17–20 |
T13662 | 1566-1567 | -RRB- | denotes | ) |
T13663 | 1568-1571 | CC | denotes | and |
T13664 | 1572-1579 | JJ | denotes | healthy |
T13665 | 1580-1588 | NN | denotes | controls |
T13666 | 1589-1590 | -LRB- | denotes | ( |
T13667 | 1590-1599 | NN | denotes | n = 15–19 |
T13668 | 1599-1600 | -RRB- | denotes | ) |
T13669 | 1601-1605 | VB | denotes | were |
T13670 | 1606-1612 | VB | denotes | primed |
T13671 | 1613-1617 | IN | denotes | with |
T13672 | 1618-1621 | NN | denotes | LPS |
T13673 | 1622-1623 | -LRB- | denotes | ( |
T13674 | 1623-1625 | CD | denotes | 10 |
T13675 | 1626-1631 | NN | denotes | ng/ml |
T13676 | 1631-1632 | -RRB- | denotes | ) |
T13677 | 1633-1642 | JJ | denotes | overnight |
T13678 | 1643-1646 | CC | denotes | and |
T13679 | 1647-1657 | VB | denotes | stimulated |
T13680 | 1658-1662 | IN | denotes | with |
T13681 | 1663-1665 | NNP | denotes | P. |
T13682 | 1666-1676 | NN | denotes | aeruginosa |
T13683 | 1677-1681 | NN | denotes | PAO1 |
T13684 | 1682-1683 | -LRB- | denotes | ( |
T13685 | 1683-1690 | NN | denotes | MOI = 1 |
T13686 | 1690-1691 | -RRB- | denotes | ) |
T13687 | 1691-1692 | -COMMA- | denotes | , |
T13688 | 1693-1695 | NNP | denotes | P. |
T13689 | 1696-1706 | NN | denotes | aeruginosa |
T13690 | 1707-1711 | NN | denotes | PAO1 |
T13691 | 1712-1719 | VB | denotes | lacking |
T13692 | 1720-1724 | NN | denotes | exsA |
T13693 | 1725-1726 | -LRB- | denotes | ( |
T13694 | 1726-1733 | NN | denotes | MOI = 1 |
T13695 | 1733-1734 | -RRB- | denotes | ) |
T13696 | 1734-1735 | -COMMA- | denotes | , |
T13697 | 1736-1739 | NN | denotes | ATP |
T13698 | 1740-1741 | -LRB- | denotes | ( |
T13699 | 1741-1742 | CD | denotes | 5 |
T13700 | 1743-1745 | NN | denotes | mM |
T13701 | 1745-1746 | -RRB- | denotes | ) |
T13702 | 1746-1747 | -COMMA- | denotes | , |
T13703 | 1748-1750 | CC | denotes | or |
T13704 | 1751-1755 | NNP | denotes | Poly |
T13705 | 1755-1756 | -LRB- | denotes | ( |
T13706 | 1756-1758 | NN | denotes | dA |
T13707 | 1758-1759 | -COLON- | denotes | : |
T13708 | 1759-1761 | NN | denotes | dT |
T13709 | 1761-1762 | -RRB- | denotes | ) |
T13710 | 1763-1764 | -LRB- | denotes | ( |
T13711 | 1764-1765 | CD | denotes | 1 |
T13712 | 1766-1771 | NN | denotes | µg/ml |
T13713 | 1771-1772 | -RRB- | denotes | ) |
T13714 | 1773-1776 | IN | denotes | for |
T13715 | 1777-1779 | CD | denotes | 24 |
T13716 | 1780-1785 | NN | denotes | hours |
T13717 | 1787-1789 | NN | denotes | P. |
T13718 | 1790-1800 | NN | denotes | aeruginosa |
T13719 | 1801-1808 | VB | denotes | lacking |
T13720 | 1809-1813 | NN | denotes | exsA |
T13721 | 1814-1817 | VB | denotes | was |
T13722 | 1818-1822 | VB | denotes | used |
T13723 | 1823-1825 | IN | denotes | as |
T13724 | 1826-1827 | DT | denotes | a |
T13725 | 1828-1832 | NN | denotes | type |
T13726 | 1833-1836 | CD | denotes | III |
T13727 | 1837-1846 | NN | denotes | secretion |
T13728 | 1847-1854 | NN | denotes | control |
T13729 | 1855-1857 | IN | denotes | in |
T13730 | 1858-1868 | NN | denotes | comparison |
T13731 | 1869-1873 | IN | denotes | with |
T13732 | 1874-1883 | JJ | denotes | wild-type |
T13733 | 1884-1886 | NNP | denotes | P. |
T13734 | 1887-1897 | NN | denotes | aeruginosa |
T13735 | 1899-1911 | NN | denotes | Supernatants |
T13736 | 1912-1916 | VB | denotes | were |
T13737 | 1917-1924 | VB | denotes | assayed |
T13738 | 1925-1928 | IN | denotes | for |
T13739 | 1929-1930 | -LRB- | denotes | ( |
T13740 | 1930-1931 | NN | denotes | A |
T13741 | 1931-1932 | -RRB- | denotes | ) |
T13742 | 1933-1938 | NN | denotes | IL-1β |
T13743 | 1939-1942 | CC | denotes | and |
T13744 | 1943-1944 | -LRB- | denotes | ( |
T13745 | 1944-1945 | NN | denotes | B |
T13746 | 1945-1946 | -RRB- | denotes | ) |
T13747 | 1947-1951 | NN | denotes | IL-8 |
R3130 | T3638 | T3639 | arg1Of | PBMCs,from |
R3131 | T3638 | T3642 | arg1Of | PBMCs,do |
R3132 | T3638 | T3644 | arg1Of | PBMCs,produce |
R3133 | T3641 | T3639 | arg2Of | patients,from |
R3134 | T3641 | T3640 | arg1Of | patients,CF |
R3135 | T3644 | T3642 | arg2Of | produce,do |
R3136 | T3644 | T3643 | arg1Of | produce,not |
R3137 | T3644 | T3649 | arg1Of | produce,upon |
R3138 | T3646 | T3644 | arg2Of | amounts,produce |
R3139 | T3646 | T3645 | arg2Of | amounts,increased |
R3140 | T3646 | T3647 | arg1Of | amounts,of |
R3141 | T3648 | T3647 | arg2Of | IL-1β,of |
R3142 | T3651 | T3649 | arg2Of | stimulation,upon |
R3143 | T3651 | T3650 | arg1Of | stimulation,inflammasome |
R3144 | T3653 | T3652 | arg1Of | studies,Previous |
R3145 | T3653 | T3654 | arg1Of | studies,have |
R3146 | T3653 | T3655 | arg1Of | studies,shown |
R3147 | T3655 | T3654 | arg2Of | shown,have |
R3148 | T3655 | T3681 | arg1Of | shown,"," |
R3149 | T3655 | T3682 | arg1Of | shown,[ |
R3150 | T3655 | T3685 | arg1Of | shown,"," |
R3151 | T3655 | T3686 | arg1Of | shown,[ |
R3152 | T3658 | T3657 | arg1Of | loss,the |
R3153 | T3658 | T3659 | arg1Of | loss,of |
R3154 | T3658 | T3661 | arg1Of | loss,results |
R3155 | T3660 | T3659 | arg2Of | CFTR,of |
R3156 | T3661 | T3655 | arg2Of | results,shown |
R3157 | T3661 | T3656 | arg1Of | results,that |
R3158 | T3661 | T3662 | arg1Of | results,in |
R3159 | T3661 | T3673 | arg1Of | results,"," |
R3160 | T3661 | T3674 | arg1Of | results,[ |
R3161 | T3661 | T3677 | arg1Of | results,"," |
R3162 | T3661 | T3678 | arg1Of | results,[ |
R3163 | T3665 | T3663 | arg2Of | activity,increased |
R3164 | T3665 | T3664 | arg1Of | activity,NF-κB |
R3165 | T3665 | T3666 | arg1Of | activity,and |
R3166 | T3666 | T3662 | arg2Of | and,in |
R3167 | T3669 | T3666 | arg2Of | secretion,and |
R3168 | T3669 | T3667 | arg1Of | secretion,pro-inflammatory |
R3169 | T3669 | T3668 | arg1Of | secretion,cytokine |
R3170 | T3669 | T3670 | arg1Of | secretion,[ |
R3171 | T3671 | T3670 | arg2Of | 4,[ |
R3172 | T3672 | T3670 | arg3Of | ],[ |
R3173 | T3675 | T3674 | arg2Of | 5,[ |
R3174 | T3676 | T3674 | arg3Of | ],[ |
R3175 | T3679 | T3678 | arg2Of | 32,[ |
R3176 | T3680 | T3678 | arg3Of | ],[ |
R3177 | T3683 | T3682 | arg2Of | 36,[ |
R3178 | T3684 | T3682 | arg3Of | ],[ |
R3179 | T3687 | T3686 | arg2Of | 37,[ |
R3180 | T3688 | T3686 | arg3Of | ],[ |
R3181 | T3691 | T3689 | arg1Of | examine,To |
R3182 | T3691 | T3690 | arg1Of | examine,further |
R3183 | T3693 | T3691 | arg2Of | relationship,examine |
R3184 | T3693 | T3692 | arg1Of | relationship,this |
R3185 | T3695 | T3691 | arg1Of | PBMCs,examine |
R3186 | T3695 | T3696 | arg1Of | PBMCs,from |
R3187 | T3695 | T3703 | arg1Of | PBMCs,were |
R3188 | T3695 | T3704 | arg2Of | PBMCs,stimulated |
R3189 | T3698 | T3697 | arg1Of | patients,CF |
R3190 | T3698 | T3699 | arg1Of | patients,and |
R3191 | T3699 | T3696 | arg2Of | and,from |
R3192 | T3701 | T3700 | arg1Of | adult,healthy |
R3193 | T3702 | T3699 | arg2Of | controls,and |
R3194 | T3702 | T3701 | arg1Of | controls,adult |
R3195 | T3704 | T3689 | modOf | stimulated,To |
R3196 | T3704 | T3694 | arg1Of | stimulated,"," |
R3197 | T3704 | T3703 | arg2Of | stimulated,were |
R3198 | T3704 | T3705 | arg1Of | stimulated,with |
R3199 | T3706 | T3707 | arg1Of | PAO1,"," |
R3200 | T3707 | T3710 | arg1Of | ",",and |
R3201 | T3708 | T3707 | arg2Of | LPS+ATP,"," |
R3202 | T3710 | T3705 | arg2Of | and,with |
R3203 | T3710 | T3709 | arg1Of | and,"," |
R3204 | T3710 | T3717 | arg1Of | and,"," |
R3205 | T3711 | T3710 | arg2Of | LPS+Poly,and |
R3206 | T3711 | T3712 | arg1Of | LPS+Poly,( |
R3207 | T3713 | T3712 | arg2Of | dA,( |
R3208 | T3713 | T3714 | arg1Of | dA,: |
R3209 | T3713 | T3715 | arg1Of | dA,dT |
R3210 | T3716 | T3712 | arg3Of | ),( |
R3211 | T3719 | T3717 | arg2Of | activate,"," |
R3212 | T3719 | T3718 | arg1Of | activate,to |
R3213 | T3719 | T3728 | arg1Of | activate,"," |
R3214 | T3719 | T3729 | arg1Of | activate,respectively |
R3215 | T3721 | T3722 | arg1Of | NLRC4,"," |
R3216 | T3722 | T3725 | arg1Of | ",",and |
R3217 | T3723 | T3722 | arg2Of | NLRP3,"," |
R3218 | T3725 | T3724 | arg1Of | and,"," |
R3219 | T3726 | T3725 | arg2Of | AIM2,and |
R3220 | T3727 | T3719 | arg2Of | inflammasomes,activate |
R3221 | T3727 | T3720 | arg1Of | inflammasomes,the |
R3222 | T3727 | T3721 | arg1Of | inflammasomes,NLRC4 |
R3223 | T3727 | T3723 | arg1Of | inflammasomes,NLRP3 |
R3224 | T3727 | T3726 | arg1Of | inflammasomes,AIM2 |
R3225 | T3732 | T3730 | arg2Of | hours,By |
R3226 | T3732 | T3731 | arg1Of | hours,24 |
R3227 | T3732 | T3733 | arg1Of | hours,of |
R3228 | T3734 | T3733 | arg2Of | stimulation,of |
R3229 | T3737 | T3736 | arg1Of | PBMCs,CF |
R3230 | T3737 | T3738 | arg1Of | PBMCs,did |
R3231 | T3737 | T3740 | arg1Of | PBMCs,produce |
R3232 | T3737 | T3756 | arg1Of | PBMCs,compared |
R3233 | T3740 | T3730 | arg1Of | produce,By |
R3234 | T3740 | T3735 | arg1Of | produce,"," |
R3235 | T3740 | T3738 | arg2Of | produce,did |
R3236 | T3740 | T3739 | arg1Of | produce,not |
R3237 | T3740 | T3755 | arg1Of | produce,when |
R3238 | T3742 | T3740 | arg2Of | amounts,produce |
R3239 | T3742 | T3741 | arg2Of | amounts,increased |
R3240 | T3742 | T3743 | arg1Of | amounts,of |
R3241 | T3744 | T3745 | arg1Of | IL-1β,( |
R3242 | T3744 | T3749 | arg1Of | IL-1β,or |
R3243 | T3747 | T3745 | arg2Of | 5a,( |
R3244 | T3747 | T3746 | arg1Of | 5a,Fig. |
R3245 | T3748 | T3745 | arg3Of | ),( |
R3246 | T3749 | T3743 | arg2Of | or,of |
R3247 | T3750 | T3749 | arg2Of | IL-8,or |
R3248 | T3750 | T3751 | arg1Of | IL-8,( |
R3249 | T3753 | T3751 | arg2Of | 5b,( |
R3250 | T3753 | T3752 | arg1Of | 5b,Fig. |
R3251 | T3754 | T3751 | arg3Of | ),( |
R3252 | T3756 | T3755 | arg2Of | compared,when |
R3253 | T3756 | T3757 | arg1Of | compared,to |
R3254 | T3759 | T3757 | arg2Of | controls,to |
R3255 | T3759 | T3758 | arg1Of | controls,healthy |
R3256 | T3762 | T3763 | arg1Of | we,did |
R3257 | T3762 | T3764 | arg1Of | we,notice |
R3258 | T3764 | T3760 | arg1Of | notice,However |
R3259 | T3764 | T3761 | arg1Of | notice,"," |
R3260 | T3764 | T3763 | arg2Of | notice,did |
R3261 | T3764 | T3773 | arg1Of | notice,in |
R3262 | T3767 | T3764 | arg2Of | decrease,notice |
R3263 | T3767 | T3765 | arg1Of | decrease,a |
R3264 | T3767 | T3766 | arg1Of | decrease,transient |
R3265 | T3767 | T3768 | arg1Of | decrease,( |
R3266 | T3769 | T3768 | arg2Of | P,( |
R3267 | T3769 | T3770 | arg1Of | P,< |
R3268 | T3769 | T3771 | arg1Of | P,0.001 |
R3269 | T3772 | T3768 | arg3Of | ),( |
R3270 | T3775 | T3773 | arg2Of | amount,in |
R3271 | T3775 | T3774 | arg1Of | amount,the |
R3272 | T3775 | T3776 | arg1Of | amount,of |
R3273 | T3775 | T3778 | arg2Of | amount,produced |
R3274 | T3777 | T3776 | arg2Of | IL-1β,of |
R3275 | T3778 | T3782 | arg1Of | produced,in |
R3276 | T3778 | T3786 | arg1Of | produced,at |
R3277 | T3781 | T3778 | arg1Of | cells,produced |
R3278 | T3781 | T3779 | arg2Of | cells,by |
R3279 | T3781 | T3780 | arg1Of | cells,CF |
R3280 | T3782 | T3784 | arg1Of | in,to |
R3281 | T3783 | T3782 | arg2Of | response,in |
R3282 | T3785 | T3782 | arg3Of | LPS+ATP,in |
R3283 | T3788 | T3786 | arg2Of | hours,at |
R3284 | T3788 | T3787 | arg1Of | hours,6 |
R3285 | T3788 | T3789 | arg1Of | hours,( |
R3286 | T3790 | T3789 | arg2Of | data,( |
R3287 | T3790 | T3792 | arg2Of | data,shown |
R3288 | T3792 | T3791 | arg1Of | shown,not |
R3289 | T3793 | T3789 | arg3Of | ),( |
R3290 | T3794 | T3795 | arg1Of | Stimulation,of |
R3291 | T3794 | T3797 | arg1Of | Stimulation,with |
R3292 | T3794 | T3800 | arg1Of | Stimulation,that |
R3293 | T3794 | T3801 | arg1Of | Stimulation,lacks |
R3294 | T3794 | T3815 | arg1Of | Stimulation,produced |
R3295 | T3796 | T3795 | arg2Of | PBMCs,of |
R3296 | T3799 | T3797 | arg2Of | aeruginosa,with |
R3297 | T3799 | T3798 | arg1Of | aeruginosa,P. |
R3298 | T3802 | T3801 | arg2Of | exsA,lacks |
R3299 | T3802 | T3803 | arg1Of | exsA,( |
R3300 | T3802 | T3806 | arg1Of | exsA,"," |
R3301 | T3804 | T3803 | arg2Of | PAO1ΔexsA,( |
R3302 | T3805 | T3803 | arg3Of | ),( |
R3303 | T3809 | T3806 | arg2Of | regulator,"," |
R3304 | T3809 | T3807 | arg1Of | regulator,a |
R3305 | T3809 | T3808 | arg1Of | regulator,key |
R3306 | T3809 | T3810 | arg1Of | regulator,of |
R3307 | T3813 | T3810 | arg2Of | secretion,of |
R3308 | T3813 | T3811 | arg1Of | secretion,type |
R3309 | T3813 | T3812 | arg1Of | secretion,III |
R3310 | T3815 | T3814 | arg1Of | produced,"," |
R3311 | T3815 | T3819 | arg1Of | produced,compared |
R3312 | T3815 | T3825 | arg1Of | produced,by |
R3313 | T3817 | T3816 | arg1Of | less,three-fold |
R3314 | T3818 | T3815 | arg2Of | IL-1β,produced |
R3315 | T3818 | T3817 | arg1Of | IL-1β,less |
R3316 | T3820 | T3819 | arg2Of | to,compared |
R3317 | T3824 | T3820 | arg2Of | strain,to |
R3318 | T3824 | T3821 | arg1Of | strain,the |
R3319 | T3824 | T3822 | arg1Of | strain,parental |
R3320 | T3824 | T3823 | arg1Of | strain,PAO1 |
R3321 | T3827 | T3825 | arg2Of | hours,by |
R3322 | T3827 | T3826 | arg1Of | hours,24 |
R3323 | T3827 | T3828 | arg1Of | hours,( |
R3324 | T3830 | T3828 | arg2Of | 5a,( |
R3325 | T3830 | T3829 | arg1Of | 5a,Fig. |
R3326 | T3831 | T3828 | arg3Of | ),( |
R3327 | T3833 | T3832 | arg1Of | stimulation,Inflammasome |
R3328 | T3833 | T3834 | arg1Of | stimulation,without |
R3329 | T3833 | T3836 | arg1Of | stimulation,did |
R3330 | T3833 | T3838 | arg1Of | stimulation,result |
R3331 | T3835 | T3834 | arg2Of | priming,without |
R3332 | T3838 | T3836 | arg2Of | result,did |
R3333 | T3838 | T3837 | arg1Of | result,not |
R3334 | T3838 | T3839 | arg1Of | result,in |
R3335 | T3842 | T3839 | arg2Of | production,in |
R3336 | T3842 | T3840 | arg1Of | production,any |
R3337 | T3842 | T3841 | arg1Of | production,IL-1β |
R3338 | T3842 | T3843 | arg1Of | production,in |
R3339 | T3845 | T3846 | arg1Of | CF,or |
R3340 | T3846 | T3843 | arg2Of | or,in |
R3341 | T3846 | T3844 | arg1Of | or,either |
R3342 | T3848 | T3846 | arg2Of | PBMCs,or |
R3343 | T3848 | T3847 | arg1Of | PBMCs,control |
R3344 | T3849 | T3850 | arg1Of | Contrary,to |
R3345 | T3852 | T3850 | arg2Of | hypothesis,to |
R3346 | T3852 | T3851 | arg1Of | hypothesis,our |
R3347 | T3855 | T3854 | arg1Of | results,these |
R3348 | T3855 | T3856 | arg1Of | results,indicate |
R3349 | T3856 | T3849 | arg1Of | indicate,Contrary |
R3350 | T3856 | T3853 | arg1Of | indicate,"," |
R3351 | T3858 | T3859 | arg1Of | PBMCs,from |
R3352 | T3858 | T3862 | arg1Of | PBMCs,do |
R3353 | T3858 | T3864 | arg1Of | PBMCs,display |
R3354 | T3861 | T3859 | arg2Of | patients,from |
R3355 | T3861 | T3860 | arg1Of | patients,CF |
R3356 | T3864 | T3862 | arg2Of | display,do |
R3357 | T3864 | T3863 | arg1Of | display,not |
R3358 | T3864 | T3874 | arg1Of | display,nor |
R3359 | T3866 | T3864 | arg2Of | production,display |
R3360 | T3866 | T3865 | arg2Of | production,increased |
R3361 | T3866 | T3867 | arg1Of | production,of |
R3362 | T3866 | T3871 | arg1Of | production,with |
R3363 | T3868 | T3869 | arg1Of | IL-1β,or |
R3364 | T3869 | T3867 | arg2Of | or,of |
R3365 | T3870 | T3869 | arg2Of | IL-8,or |
R3366 | T3873 | T3871 | arg2Of | activation,with |
R3367 | T3873 | T3872 | arg1Of | activation,inflammasome |
R3368 | T3874 | T3857 | arg1Of | nor,that |
R3369 | T3874 | T3877 | arg1Of | nor,suggest |
R3370 | T3875 | T3874 | arg2Of | do,nor |
R3371 | T3876 | T3875 | arg1Of | they,do |
R3372 | T3877 | T3856 | arg2Of | suggest,indicate |
R3373 | T3880 | T3881 | arg1Of | basal,or |
R3374 | T3880 | T3882 | arg2Of | basal,induced |
R3375 | T3884 | T3877 | arg2Of | activity,suggest |
R3376 | T3884 | T3878 | arg1Of | activity,any |
R3377 | T3884 | T3879 | arg2Of | activity,increased |
R3378 | T3884 | T3880 | arg1Of | activity,basal |
R3379 | T3884 | T3883 | arg1Of | activity,NF-κB |
R3380 | T3886 | T3885 | arg1Of | results,These |
R3381 | T3886 | T3887 | arg1Of | results,are |
R3382 | T3886 | T3888 | arg1Of | results,consistent |
R3383 | T3888 | T3887 | arg2Of | consistent,are |
R3384 | T3888 | T3889 | arg1Of | consistent,with |
R3385 | T3891 | T3889 | arg2Of | observation,with |
R3386 | T3891 | T3890 | arg1Of | observation,our |
R3387 | T3894 | T3893 | arg1Of | activity,caspase-1 |
R3388 | T3894 | T3895 | arg1Of | activity,is |
R3389 | T3894 | T3897 | arg1Of | activity,different |
R3390 | T3895 | T3891 | arg2Of | is,observation |
R3391 | T3895 | T3892 | arg1Of | is,that |
R3392 | T3895 | T3896 | arg1Of | is,not |
R3393 | T3897 | T3895 | arg2Of | different,is |
R3394 | T3897 | T3898 | arg1Of | different,between |
R3395 | T3899 | T3900 | arg1Of | CF,and |
R3396 | T3901 | T3900 | arg2Of | control,and |
R3397 | T3902 | T3898 | arg2Of | PBMCs,between |
R3398 | T3902 | T3899 | arg1Of | PBMCs,CF |
R3399 | T3902 | T3901 | arg1Of | PBMCs,control |
R3400 | T3902 | T3903 | arg1Of | PBMCs,( |
R3401 | T3904 | T3903 | arg2Of | Fig.,( |
R3402 | T3904 | T3905 | arg1Of | Fig.,4 |
R3403 | T3906 | T3903 | arg3Of | ),( |
R12104 | T13645 | T13651 | arg1Of | PBMCs,produce |
R12105 | T13645 | T13646 | arg1Of | PBMCs,from |
R12106 | T13645 | T13649 | arg1Of | PBMCs,do |
R12107 | T13648 | T13646 | arg2Of | patients,from |
R12108 | T13648 | T13647 | arg1Of | patients,CF |
R12109 | T13651 | T13650 | arg1Of | produce,not |
R12110 | T13651 | T13649 | arg2Of | produce,do |
R12111 | T13653 | T13651 | arg2Of | amounts,produce |
R12112 | T13653 | T13652 | arg2Of | amounts,increased |
R12113 | T13653 | T13654 | arg1Of | amounts,of |
R12114 | T13655 | T13654 | arg2Of | IL-1β,of |
R12115 | T13656 | T13657 | arg1Of | PBMCs,from |
R12116 | T13656 | T13703 | arg1Of | PBMCs,or |
R12117 | T13658 | T13669 | modOf | CF,were |
R12118 | T13659 | T13660 | arg1Of | patients,( |
R12119 | T13659 | T13663 | arg1Of | patients,and |
R12120 | T13661 | T13660 | arg2Of | n = 17–20,( |
R12121 | T13662 | T13660 | arg3Of | ),( |
R12122 | T13663 | T13669 | arg1Of | and,were |
R12123 | T13663 | T13670 | arg2Of | and,primed |
R12124 | T13665 | T13663 | arg2Of | controls,and |
R12125 | T13665 | T13664 | arg1Of | controls,healthy |
R12126 | T13665 | T13666 | arg1Of | controls,( |
R12127 | T13667 | T13666 | arg2Of | n = 15–19,( |
R12128 | T13668 | T13666 | arg3Of | ),( |
R12129 | T13670 | T13669 | arg2Of | primed,were |
R12130 | T13670 | T13671 | arg1Of | primed,with |
R12131 | T13672 | T13671 | arg2Of | LPS,with |
R12132 | T13672 | T13673 | arg1Of | LPS,( |
R12133 | T13675 | T13673 | arg2Of | ng/ml,( |
R12134 | T13675 | T13674 | arg1Of | ng/ml,10 |
R12135 | T13676 | T13673 | arg3Of | ),( |
R12136 | T13677 | T13678 | arg1Of | overnight,and |
R12137 | T13678 | T13687 | arg1Of | and,"," |
R12138 | T13679 | T13678 | arg2Of | stimulated,and |
R12139 | T13679 | T13680 | arg1Of | stimulated,with |
R12140 | T13683 | T13680 | arg2Of | PAO1,with |
R12141 | T13683 | T13681 | arg1Of | PAO1,P. |
R12142 | T13683 | T13682 | arg1Of | PAO1,aeruginosa |
R12143 | T13683 | T13684 | arg1Of | PAO1,( |
R12144 | T13685 | T13684 | arg2Of | MOI = 1,( |
R12145 | T13686 | T13684 | arg3Of | ),( |
R12146 | T13690 | T13658 | arg1Of | PAO1,CF |
R12147 | T13690 | T13677 | arg1Of | PAO1,overnight |
R12148 | T13690 | T13679 | arg2Of | PAO1,stimulated |
R12149 | T13690 | T13688 | arg1Of | PAO1,P. |
R12150 | T13690 | T13689 | arg1Of | PAO1,aeruginosa |
R12151 | T13690 | T13691 | arg1Of | PAO1,lacking |
R12152 | T13690 | T13696 | arg1Of | PAO1,"," |
R12153 | T13692 | T13691 | arg2Of | exsA,lacking |
R12154 | T13692 | T13693 | arg1Of | exsA,( |
R12155 | T13694 | T13693 | arg2Of | MOI = 1,( |
R12156 | T13695 | T13693 | arg3Of | ),( |
R12157 | T13696 | T13657 | arg2Of | ",",from |
R12158 | T13697 | T13696 | arg2Of | ATP,"," |
R12159 | T13697 | T13698 | arg1Of | ATP,( |
R12160 | T13700 | T13698 | arg2Of | mM,( |
R12161 | T13700 | T13699 | arg1Of | mM,5 |
R12162 | T13701 | T13698 | arg3Of | ),( |
R12163 | T13703 | T13702 | arg1Of | or,"," |
R12164 | T13703 | T13714 | arg1Of | or,for |
R12165 | T13704 | T13703 | arg2Of | Poly,or |
R12166 | T13704 | T13705 | arg1Of | Poly,( |
R12167 | T13704 | T13710 | arg1Of | Poly,( |
R12168 | T13706 | T13705 | arg2Of | dA,( |
R12169 | T13706 | T13707 | arg1Of | dA,: |
R12170 | T13706 | T13708 | arg1Of | dA,dT |
R12171 | T13709 | T13705 | arg3Of | ),( |
R12172 | T13712 | T13710 | arg2Of | µg/ml,( |
R12173 | T13712 | T13711 | arg1Of | µg/ml,1 |
R12174 | T13713 | T13710 | arg3Of | ),( |
R12175 | T13716 | T13714 | arg2Of | hours,for |
R12176 | T13716 | T13715 | arg1Of | hours,24 |
R12177 | T13718 | T13717 | arg1Of | aeruginosa,P. |
R12178 | T13718 | T13719 | arg1Of | aeruginosa,lacking |
R12179 | T13718 | T13721 | arg1Of | aeruginosa,was |
R12180 | T13718 | T13722 | arg2Of | aeruginosa,used |
R12181 | T13720 | T13719 | arg2Of | exsA,lacking |
R12182 | T13722 | T13721 | arg2Of | used,was |
R12183 | T13722 | T13723 | arg1Of | used,as |
R12184 | T13722 | T13729 | arg1Of | used,in |
R12185 | T13728 | T13723 | arg2Of | control,as |
R12186 | T13728 | T13724 | arg1Of | control,a |
R12187 | T13728 | T13725 | arg1Of | control,type |
R12188 | T13728 | T13726 | arg1Of | control,III |
R12189 | T13728 | T13727 | arg1Of | control,secretion |
R12190 | T13730 | T13729 | arg2Of | comparison,in |
R12191 | T13730 | T13731 | arg1Of | comparison,with |
R12192 | T13734 | T13731 | arg2Of | aeruginosa,with |
R12193 | T13734 | T13732 | arg1Of | aeruginosa,wild-type |
R12194 | T13734 | T13733 | arg1Of | aeruginosa,P. |
R12195 | T13735 | T13736 | arg1Of | Supernatants,were |
R12196 | T13735 | T13737 | arg2Of | Supernatants,assayed |
R12197 | T13737 | T13736 | arg2Of | assayed,were |
R12198 | T13737 | T13738 | arg1Of | assayed,for |
R12199 | T13740 | T13739 | arg2Of | A,( |
R12200 | T13741 | T13739 | arg3Of | ),( |
R12201 | T13742 | T13739 | arg1Of | IL-1β,( |
R12202 | T13742 | T13743 | arg1Of | IL-1β,and |
R12203 | T13743 | T13738 | arg2Of | and,for |
R12204 | T13745 | T13744 | arg2Of | B,( |
R12205 | T13746 | T13744 | arg3Of | ),( |
R12206 | T13747 | T13743 | arg2Of | IL-8,and |
R12207 | T13747 | T13744 | arg1Of | IL-8,( |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3629 | 0-94 | Sentence | denotes | PBMCs from CF patients do not produce increased amounts of IL-1β upon inflammasome stimulation |
T3630 | 95-248 | Sentence | denotes | Previous studies have shown that the loss of CFTR results in increased NF-κB activity and pro-inflammatory cytokine secretion [4], [5], [32], [36], [37]. |
T3631 | 249-461 | Sentence | denotes | To further examine this relationship, PBMCs from CF patients and healthy adult controls were stimulated with PAO1, LPS+ATP, and LPS+Poly(dA:dT), to activate the NLRC4, NLRP3, and AIM2 inflammasomes, respectively. |
T3632 | 462-604 | Sentence | denotes | By 24 hours of stimulation, CF PBMCs did not produce increased amounts of IL-1β (Fig. 5a) or IL-8 (Fig. 5b) when compared to healthy controls. |
T3633 | 605-754 | Sentence | denotes | However, we did notice a transient decrease (P<0.001) in the amount of IL-1β produced by CF cells in response to LPS+ATP at 6 hours (data not shown). |
T3634 | 755-953 | Sentence | denotes | Stimulation of PBMCs with P. aeruginosa that lacks exsA (PAO1ΔexsA), a key regulator of type III secretion, produced three-fold less IL-1β compared to the parental PAO1 strain by 24 hours (Fig. 5a). |
T3635 | 954-1064 | Sentence | denotes | Inflammasome stimulation without priming did not result in any IL-1β production in either CF or control PBMCs. |
T3636 | 1065-1292 | Sentence | denotes | Contrary to our hypothesis, these results indicate that PBMCs from CF patients do not display increased production of IL-1β or IL-8 with inflammasome activation nor do they suggest any increased basal or induced NF-κB activity. |
T3637 | 1293-1422 | Sentence | denotes | These results are consistent with our observation that caspase-1 activity is not different between CF and control PBMCs (Fig. 4). |
T13641 | 1467-1532 | Sentence | denotes | PBMCs from CF patients do not produce increased amounts of IL-1β. |
T13642 | 1533-1786 | Sentence | denotes | PBMCs from CF patients (n = 17–20) and healthy controls (n = 15–19) were primed with LPS (10 ng/ml) overnight and stimulated with P. aeruginosa PAO1 (MOI = 1), P. aeruginosa PAO1 lacking exsA (MOI = 1), ATP (5 mM), or Poly(dA:dT) (1 µg/ml) for 24 hours. |
T13643 | 1787-1898 | Sentence | denotes | P. aeruginosa lacking exsA was used as a type III secretion control in comparison with wild-type P. aeruginosa. |
T13644 | 1899-1952 | Sentence | denotes | Supernatants were assayed for (A) IL-1β and (B) IL-8. |
T76 | 0-94 | Sentence | denotes | PBMCs from CF patients do not produce increased amounts of IL-1β upon inflammasome stimulation |
T77 | 95-248 | Sentence | denotes | Previous studies have shown that the loss of CFTR results in increased NF-κB activity and pro-inflammatory cytokine secretion [4], [5], [32], [36], [37]. |
T78 | 249-461 | Sentence | denotes | To further examine this relationship, PBMCs from CF patients and healthy adult controls were stimulated with PAO1, LPS+ATP, and LPS+Poly(dA:dT), to activate the NLRC4, NLRP3, and AIM2 inflammasomes, respectively. |
T79 | 462-604 | Sentence | denotes | By 24 hours of stimulation, CF PBMCs did not produce increased amounts of IL-1β (Fig. 5a) or IL-8 (Fig. 5b) when compared to healthy controls. |
T80 | 605-754 | Sentence | denotes | However, we did notice a transient decrease (P<0.001) in the amount of IL-1β produced by CF cells in response to LPS+ATP at 6 hours (data not shown). |
T81 | 755-953 | Sentence | denotes | Stimulation of PBMCs with P. aeruginosa that lacks exsA (PAO1ΔexsA), a key regulator of type III secretion, produced three-fold less IL-1β compared to the parental PAO1 strain by 24 hours (Fig. 5a). |
T82 | 954-1064 | Sentence | denotes | Inflammasome stimulation without priming did not result in any IL-1β production in either CF or control PBMCs. |
T83 | 1065-1292 | Sentence | denotes | Contrary to our hypothesis, these results indicate that PBMCs from CF patients do not display increased production of IL-1β or IL-8 with inflammasome activation nor do they suggest any increased basal or induced NF-κB activity. |
T84 | 1293-1422 | Sentence | denotes | These results are consistent with our observation that caspase-1 activity is not different between CF and control PBMCs (Fig. 4). |
T85 | 1423-1532 | Sentence | denotes | 10.1371/journal.pone.0037689.g005 Figure 5 PBMCs from CF patients do not produce increased amounts of IL-1β. |
T86 | 1533-1786 | Sentence | denotes | PBMCs from CF patients (n = 17–20) and healthy controls (n = 15–19) were primed with LPS (10 ng/ml) overnight and stimulated with P. aeruginosa PAO1 (MOI = 1), P. aeruginosa PAO1 lacking exsA (MOI = 1), ATP (5 mM), or Poly(dA:dT) (1 µg/ml) for 24 hours. |
T87 | 1787-1898 | Sentence | denotes | P. aeruginosa lacking exsA was used as a type III secretion control in comparison with wild-type P. aeruginosa. |
T88 | 1899-1952 | Sentence | denotes | Supernatants were assayed for (A) IL-1β and (B) IL-8. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
22649552-10970832-88306709 | 222-223 | 10970832 | denotes | 4 |
22649552-11404248-88306710 | 227-228 | 11404248 | denotes | 5 |
22649552-20543983-88306711 | 232-234 | 20543983 | denotes | 32 |
22649552-19247502-88306712 | 238-240 | 19247502 | denotes | 36 |
22649552-20644644-88306713 | 244-246 | 20644644 | denotes | 37 |
T35806 | 222-223 | 10970832 | denotes | 4 |
T78747 | 227-228 | 11404248 | denotes | 5 |
T26859 | 232-234 | 20543983 | denotes | 32 |
T18939 | 238-240 | 19247502 | denotes | 36 |
T3744 | 244-246 | 20644644 | denotes | 37 |