PMC:3333881 / 981-1579 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3333881","sourcedb":"PMC","sourceid":"3333881","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3333881","text":"κB enhancer thus promoting the recruitment of p65 with displacement of IκB-α; similar findings were obtained for the NF-κB-responsive genes CSF3, LTA, NFKBIA and TLR2. Our results support a novel mechanism of NF-κB activation via physical interaction of Tat with IκB-α and p65, and may contribute to further insights into the deregulation of the inflammatory response by HIV-1.\n\nINTRODUCTION\nNuclear factor (NF)-κB transcription factors regulate the transcription of genes that are involved in the immune and inflammatory response (1). 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