PMC:3333881 / 4974-5106 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
22187158-8676466-77584431	33-35	8676466	denotes	48

Id	Subject	Object	Predicate	Lexical cue
T2091	11-22	NN	denotes	degradation
T2092	23-25	IN	denotes	of
T2093	26-31	NN	denotes	IκB-α
T2094	32-33	-LRB-	denotes	(
T2095	33-35	CD	denotes	48
T2096	35-36	-RRB-	denotes	)
T2097	36-37	-COMMA-	denotes	,
T2098	38-41	CC	denotes	and
T2099	42-51	VB	denotes	increased
T2100	52-55	DT	denotes	the
T2101	56-59	NN	denotes	p65
T2102	60-75	JJ	denotes	transcriptional
T2103	76-84	NN	denotes	activity
T2104	85-87	IN	denotes	by
T2105	88-98	VB	denotes	inhibiting
T2106	99-102	DT	denotes	the
T2107	103-118	JJ	denotes	SIRT-1-mediated
T2108	119-132	NN	denotes	deacetylation
R1891	T2093	T2092	arg2Of	IκB-α,of
R1892	T2093	T2094	arg1Of	IκB-α,(
R1893	T2095	T2094	arg2Of	48,(
R1894	T2096	T2094	arg3Of	),(
R1897	T2098	T2097	arg1Of	and,","
R1898	T2099	T2098	arg2Of	increased,and
R1899	T2099	T2104	arg1Of	increased,by
R1902	T2103	T2099	arg2Of	activity,increased
R1903	T2103	T2100	arg1Of	activity,the
R1904	T2103	T2101	arg1Of	activity,p65
R1905	T2103	T2102	arg1Of	activity,transcriptional
R1906	T2105	T2104	arg2Of	inhibiting,by
R1909	T2108	T2105	arg2Of	deacetylation,inhibiting
R1910	T2108	T2106	arg1Of	deacetylation,the
R1911	T2108	T2107	arg1Of	deacetylation,SIRT-1-mediated

Id	Subject	Object	Predicate	Lexical cue
T2994	11-22	NN	denotes	degradation
T2995	23-25	IN	denotes	of
T2996	26-31	NNP	denotes	IκB-α
T2997	32-33	-LRB-	denotes	(
T2998	33-35	CD	denotes	48
T2999	35-36	-RRB-	denotes	)
T3000	36-37	,	denotes	,
T3001	38-41	CC	denotes	and
T3002	42-51	VBD	denotes	increased
T3003	52-55	DT	denotes	the
T3004	56-59	NNS	denotes	p65
T3005	60-75	JJ	denotes	transcriptional
T3006	76-84	NN	denotes	activity
T3007	85-87	IN	denotes	by
T3008	88-98	VBG	denotes	inhibiting
T3009	99-102	DT	denotes	the
T3010	103-118	JJ	denotes	SIRT-1-mediated
T3011	119-132	NN	denotes	deacetylation
R2814	T2995	T2994	prep	of,degradation
R2815	T2996	T2995	pobj	IκB-α,of
R2816	T2997	T2996	punct	(,IκB-α
R2817	T2998	T2996	appos	48,IκB-α
R2818	T2999	T2996	punct	),IκB-α
R2822	T3003	T3006	det	the,activity
R2823	T3004	T3006	nmod	p65,activity
R2824	T3005	T3006	compound	transcriptional,activity
R2825	T3006	T3002	dobj	activity,increased
R2826	T3007	T3002	prep	by,increased
R2827	T3008	T3007	pcomp	inhibiting,by
R2828	T3009	T3011	det	the,deacetylation
R2829	T3010	T3011	amod	SIRT-1-mediated,deacetylation
R2830	T3011	T3008	dobj	deacetylation,inhibiting

Id	Subject	Object	Predicate	Lexical cue
T3168	60-75	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcriptional
T3181	11-22	http://purl.obolibrary.org/obo/GO_0009056	denotes	degradation

Id	Subject	Object	Predicate	Lexical cue
T4164	11-22	Protein_catabolism	denotes	degradation
T4165	26-31	Protein	denotes	IκB-α
T4166	56-59	Protein	denotes	p65
T4167	88-98	Negative_regulation	denotes	inhibiting
T4168	103-109	Protein	denotes	SIRT-1
T4169	110-118	Positive_regulation	denotes	mediated
T4170	119-132	Deacetylation	denotes	deacetylation
R3742	T4165	T4164	themeOf	IκB-α,degradation
R3744	T4168	T4169	causeOf	SIRT-1,mediated
R3746	T4169	T4167	themeOf	mediated,inhibiting
R3747	T4170	T4169	themeOf	deacetylation,mediated

Id	Subject	Object	Predicate	Lexical cue
T4327	26-31	Protein	denotes	IκB-α
T4328	56-59	Protein	denotes	p65
T4329	103-109	Protein	denotes	SIRT-1
T4332	11-22	Protein_catabolism	denotes	degradation
T4333	11-22	Protein_catabolism	denotes	degradation
T4334	42-51	Positive_regulation	denotes	increased
R3966	T4327	T4333	themeOf	IκB-α,degradation
R3968	T4328	T4334	themeOf	p65,increased

Id	Subject	Object	Predicate	Lexical cue
T1217	11-22	Protein_catabolism	denotes	degradation
T1218	26-31	Protein	denotes	IκB-α
T1219	42-51	Positive_regulation	denotes	increased
T1220	56-59	Protein	denotes	p65
T1221	60-75	Transcription	denotes	transcriptional
T1222	88-98	Negative_regulation	denotes	inhibiting
T1223	103-109	Protein	denotes	SIRT-1
T1224	110-118	Positive_regulation	denotes	mediated
T1225	119-132	Negative_regulation	denotes	deacetylation
R1039	T1218	T1217	themeOf	IκB-α,degradation
R1040	T1220	T1221	themeOf	p65,transcriptional
R1041	T1221	T1219	themeOf	transcriptional,increased
R1042	T1222	T1219	causeOf	inhibiting,increased
R1043	T1223	T1224	causeOf	SIRT-1,mediated
R1044	T1224	T1222	themeOf	mediated,inhibiting
R1045	T1225	T1224	themeOf	deacetylation,mediated

Id	Subject	Object	Predicate	Lexical cue
T1409	11-22	Protein_catabolism	denotes	degradation
T1410	26-31	Protein	denotes	IκB-α
T1411	56-59	Protein	denotes	p65
T1412	88-98	Negative_regulation	denotes	inhibiting
T1413	103-109	Protein	denotes	SIRT-1
T1414	110-118	Positive_regulation	denotes	mediated
T1415	119-132	Deacetylation	denotes	deacetylation
R1264	T1410	T1409	themeOf	IκB-α,degradation
R1265	T1413	T1414	causeOf	SIRT-1,mediated
R1266	T1414	T1412	themeOf	mediated,inhibiting
R1267	T1415	T1414	themeOf	deacetylation,mediated

Id	Subject	Object	Predicate	Lexical cue
T2307	56-59	Q04206	denotes	p65
T2308	56-59	P21579	denotes	p65