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PMC:3333881 / 4887-5126
Annnotations
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
22187158-8676466-77584431 | 120-122 | 8676466 | denotes | 48 |
22187158-18329615-77584432 | 235-237 | 18329615 | denotes | 49 |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2077 | 0-9 | VB | denotes | Following |
T2078 | 10-14 | NN | denotes | gene |
T2079 | 15-27 | NN | denotes | transfection |
T2080 | 28-30 | CC | denotes | or |
T2081 | 31-38 | NN | denotes | protein |
T2082 | 39-51 | NN | denotes | transduction |
T2083 | 51-52 | -COMMA- | denotes | , |
T2084 | 53-56 | NN | denotes | Tat |
T2085 | 57-64 | VB | denotes | induced |
T2086 | 65-68 | DT | denotes | the |
T2087 | 69-72 | NN | denotes | IKK |
T2088 | 73-81 | NN | denotes | activity |
T2089 | 82-85 | CC | denotes | and |
T2090 | 86-97 | JJ | denotes | proteasomal |
T2091 | 98-109 | NN | denotes | degradation |
T2092 | 110-112 | IN | denotes | of |
T2093 | 113-118 | NN | denotes | IκB-α |
T2094 | 119-120 | -LRB- | denotes | ( |
T2095 | 120-122 | CD | denotes | 48 |
T2096 | 122-123 | -RRB- | denotes | ) |
T2097 | 123-124 | -COMMA- | denotes | , |
T2098 | 125-128 | CC | denotes | and |
T2099 | 129-138 | VB | denotes | increased |
T2100 | 139-142 | DT | denotes | the |
T2101 | 143-146 | NN | denotes | p65 |
T2102 | 147-162 | JJ | denotes | transcriptional |
T2103 | 163-171 | NN | denotes | activity |
T2104 | 172-174 | IN | denotes | by |
T2105 | 175-185 | VB | denotes | inhibiting |
T2106 | 186-189 | DT | denotes | the |
T2107 | 190-205 | JJ | denotes | SIRT-1-mediated |
T2108 | 206-219 | NN | denotes | deacetylation |
T2109 | 220-222 | IN | denotes | of |
T2110 | 223-226 | NN | denotes | p65 |
T2111 | 227-233 | NN | denotes | Lys310 |
T2112 | 234-235 | -LRB- | denotes | ( |
T2113 | 235-237 | CD | denotes | 49 |
T2114 | 237-238 | -RRB- | denotes | ) |
R1868 | T2079 | T2078 | arg1Of | transfection,gene |
R1869 | T2079 | T2080 | arg1Of | transfection,or |
R1870 | T2080 | T2077 | arg2Of | or,Following |
R1872 | T2082 | T2080 | arg2Of | transduction,or |
R1873 | T2082 | T2081 | arg1Of | transduction,protein |
R1874 | T2084 | T2085 | arg1Of | Tat,induced |
R1876 | T2084 | T2099 | arg1Of | Tat,increased |
R1877 | T2084 | T2105 | arg1Of | Tat,inhibiting |
R1878 | T2085 | T2098 | arg1Of | induced,and |
R1880 | T2088 | T2087 | arg1Of | activity,IKK |
R1881 | T2088 | T2089 | arg1Of | activity,and |
R1884 | T2089 | T2085 | arg2Of | and,induced |
R1885 | T2089 | T2086 | arg1Of | and,the |
R1886 | T2089 | T2092 | arg1Of | and,of |
R1888 | T2091 | T2089 | arg2Of | degradation,and |
R1889 | T2091 | T2090 | arg1Of | degradation,proteasomal |
R1891 | T2093 | T2092 | arg2Of | IκB-α,of |
R1892 | T2093 | T2094 | arg1Of | IκB-α,( |
R1893 | T2095 | T2094 | arg2Of | 48,( |
R1894 | T2096 | T2094 | arg3Of | ),( |
R1895 | T2098 | T2077 | arg1Of | and,Following |
R1896 | T2098 | T2083 | arg1Of | and,"," |
R1897 | T2098 | T2097 | arg1Of | and,"," |
R1898 | T2099 | T2098 | arg2Of | increased,and |
R1899 | T2099 | T2104 | arg1Of | increased,by |
R1902 | T2103 | T2099 | arg2Of | activity,increased |
R1903 | T2103 | T2100 | arg1Of | activity,the |
R1904 | T2103 | T2101 | arg1Of | activity,p65 |
R1905 | T2103 | T2102 | arg1Of | activity,transcriptional |
R1906 | T2105 | T2104 | arg2Of | inhibiting,by |
R1909 | T2108 | T2105 | arg2Of | deacetylation,inhibiting |
R1910 | T2108 | T2106 | arg1Of | deacetylation,the |
R1911 | T2108 | T2107 | arg1Of | deacetylation,SIRT-1-mediated |
R1912 | T2108 | T2109 | arg1Of | deacetylation,of |
R1914 | T2111 | T2109 | arg2Of | Lys310,of |
R1915 | T2111 | T2110 | arg1Of | Lys310,p65 |
R1916 | T2111 | T2112 | arg1Of | Lys310,( |
R1917 | T2113 | T2112 | arg2Of | 49,( |
R1918 | T2114 | T2112 | arg3Of | ),( |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2980 | 0-9 | VBG | denotes | Following |
T2981 | 10-14 | NN | denotes | gene |
T2982 | 15-27 | NN | denotes | transfection |
T2983 | 28-30 | CC | denotes | or |
T2984 | 31-38 | NN | denotes | protein |
T2985 | 39-51 | NN | denotes | transduction |
T2986 | 51-52 | , | denotes | , |
T2987 | 53-56 | NNP | denotes | Tat |
T2988 | 57-64 | VBD | denotes | induced |
T2989 | 65-68 | DT | denotes | the |
T2990 | 69-72 | NNP | denotes | IKK |
T2991 | 73-81 | NN | denotes | activity |
T2992 | 82-85 | CC | denotes | and |
T2993 | 86-97 | JJ | denotes | proteasomal |
T2994 | 98-109 | NN | denotes | degradation |
T2995 | 110-112 | IN | denotes | of |
T2996 | 113-118 | NNP | denotes | IκB-α |
T2997 | 119-120 | -LRB- | denotes | ( |
T2998 | 120-122 | CD | denotes | 48 |
T2999 | 122-123 | -RRB- | denotes | ) |
T3000 | 123-124 | , | denotes | , |
T3001 | 125-128 | CC | denotes | and |
T3002 | 129-138 | VBD | denotes | increased |
T3003 | 139-142 | DT | denotes | the |
T3004 | 143-146 | NNS | denotes | p65 |
T3005 | 147-162 | JJ | denotes | transcriptional |
T3006 | 163-171 | NN | denotes | activity |
T3007 | 172-174 | IN | denotes | by |
T3008 | 175-185 | VBG | denotes | inhibiting |
T3009 | 186-189 | DT | denotes | the |
T3010 | 190-205 | JJ | denotes | SIRT-1-mediated |
T3011 | 206-219 | NN | denotes | deacetylation |
T3012 | 220-222 | IN | denotes | of |
T3013 | 223-226 | CD | denotes | p65 |
T3014 | 227-233 | NNP | denotes | Lys310 |
T3015 | 234-235 | -LRB- | denotes | ( |
T3016 | 235-237 | CD | denotes | 49 |
T3017 | 237-238 | -RRB- | denotes | ) |
T3018 | 238-239 | . | denotes | . |
R2766 | T2980 | T2988 | prep | Following,induced |
R2770 | T2981 | T2982 | compound | gene,transfection |
R2771 | T2982 | T2980 | pobj | transfection,Following |
R2773 | T2983 | T2982 | cc | or,transfection |
R2777 | T2984 | T2985 | compound | protein,transduction |
R2782 | T2985 | T2982 | conj | transduction,transfection |
R2786 | T2986 | T2988 | punct | ",",induced |
R2789 | T2987 | T2988 | nsubj | Tat,induced |
R2791 | T2988 | T2988 | ROOT | induced,induced |
R2795 | T2989 | T2991 | det | the,activity |
R2798 | T2990 | T2991 | compound | IKK,activity |
R2802 | T2991 | T2988 | dobj | activity,induced |
R2809 | T2992 | T2991 | cc | and,activity |
R2812 | T2993 | T2994 | amod | proteasomal,degradation |
R2813 | T2994 | T2991 | conj | degradation,activity |
R2814 | T2995 | T2994 | prep | of,degradation |
R2815 | T2996 | T2995 | pobj | IκB-α,of |
R2816 | T2997 | T2996 | punct | (,IκB-α |
R2817 | T2998 | T2996 | appos | 48,IκB-α |
R2818 | T2999 | T2996 | punct | ),IκB-α |
R2819 | T3000 | T2988 | punct | ",",induced |
R2820 | T3001 | T2988 | cc | and,induced |
R2821 | T3002 | T2988 | conj | increased,induced |
R2822 | T3003 | T3006 | det | the,activity |
R2823 | T3004 | T3006 | nmod | p65,activity |
R2824 | T3005 | T3006 | compound | transcriptional,activity |
R2825 | T3006 | T3002 | dobj | activity,increased |
R2826 | T3007 | T3002 | prep | by,increased |
R2827 | T3008 | T3007 | pcomp | inhibiting,by |
R2828 | T3009 | T3011 | det | the,deacetylation |
R2829 | T3010 | T3011 | amod | SIRT-1-mediated,deacetylation |
R2830 | T3011 | T3008 | dobj | deacetylation,inhibiting |
R2831 | T3012 | T3011 | prep | of,deacetylation |
R2832 | T3013 | T3014 | compound | p65,Lys310 |
R2833 | T3014 | T3012 | pobj | Lys310,of |
R2834 | T3015 | T3014 | punct | (,Lys310 |
R2835 | T3016 | T3014 | appos | 49,Lys310 |
R2836 | T3017 | T3014 | punct | ),Lys310 |
R2837 | T3018 | T2988 | punct | .,induced |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3168 | 147-162 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptional |
T3178 | 69-72 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | IKK |
T3181 | 98-109 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
T3201 | 39-51 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3237 | 69-72 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | IKK |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1449 | 0-239 | Sentence | denotes | Following gene transfection or protein transduction, Tat induced the IKK activity and proteasomal degradation of IκB-α (48), and increased the p65 transcriptional activity by inhibiting the SIRT-1-mediated deacetylation of p65 Lys310 (49). |
T31 | 0-239 | Sentence | denotes | Following gene transfection or protein transduction, Tat induced the IKK activity and proteasomal degradation of IκB-α (48), and increased the p65 transcriptional activity by inhibiting the SIRT-1-mediated deacetylation of p65 Lys310 (49). |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4162 | 53-56 | Protein | denotes | Tat |
T4163 | 57-64 | Positive_regulation | denotes | induced |
T4164 | 98-109 | Protein_catabolism | denotes | degradation |
T4165 | 113-118 | Protein | denotes | IκB-α |
T4166 | 143-146 | Protein | denotes | p65 |
T4167 | 175-185 | Negative_regulation | denotes | inhibiting |
T4168 | 190-196 | Protein | denotes | SIRT-1 |
T4169 | 197-205 | Positive_regulation | denotes | mediated |
T4170 | 206-219 | Deacetylation | denotes | deacetylation |
T4171 | 223-226 | Protein | denotes | p65 |
T4172 | 227-233 | Entity | denotes | Lys310 |
R3737 | T4162 | T4163 | causeOf | Tat,induced |
R3738 | T4162 | T4167 | causeOf | Tat,inhibiting |
R3740 | T4164 | T4163 | themeOf | degradation,induced |
R3742 | T4165 | T4164 | themeOf | IκB-α,degradation |
R3744 | T4168 | T4169 | causeOf | SIRT-1,mediated |
R3746 | T4169 | T4167 | themeOf | mediated,inhibiting |
R3747 | T4170 | T4169 | themeOf | deacetylation,mediated |
R3750 | T4172 | T4170 | themeOf | Lys310,deacetylation |
R3751 | T4172 | T4171 | partOf | Lys310,p65 |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4325 | 53-56 | Protein | denotes | Tat |
T4326 | 69-72 | Protein | denotes | IKK |
T4327 | 113-118 | Protein | denotes | IκB-α |
T4328 | 143-146 | Protein | denotes | p65 |
T4329 | 190-196 | Protein | denotes | SIRT-1 |
T4330 | 223-233 | Protein | denotes | p65 Lys310 |
T4331 | 57-64 | Positive_regulation | denotes | induced |
T4332 | 98-109 | Protein_catabolism | denotes | degradation |
T4333 | 98-109 | Protein_catabolism | denotes | degradation |
T4334 | 129-138 | Positive_regulation | denotes | increased |
T4335 | 57-64 | Positive_regulation | denotes | induced |
T4336 | 57-64 | Positive_regulation | denotes | induced |
R3960 | T4325 | T4331 | causeOf | Tat,induced |
R3961 | T4325 | T4334 | causeOf | Tat,increased |
R3962 | T4325 | T4335 | causeOf | Tat,induced |
R3963 | T4325 | T4336 | causeOf | Tat,induced |
R3964 | T4326 | T4331 | themeOf | IKK,induced |
R3965 | T4326 | T4332 | themeOf | IKK,degradation |
R3966 | T4327 | T4333 | themeOf | IκB-α,degradation |
R3968 | T4328 | T4334 | themeOf | p65,increased |
R3971 | T4332 | T4335 | themeOf | degradation,induced |
R3972 | T4333 | T4336 | themeOf | degradation,induced |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1215 | 53-56 | Protein | denotes | Tat |
T1216 | 57-64 | Positive_regulation | denotes | induced |
T1217 | 98-109 | Protein_catabolism | denotes | degradation |
T1218 | 113-118 | Protein | denotes | IκB-α |
T1219 | 129-138 | Positive_regulation | denotes | increased |
T1220 | 143-146 | Protein | denotes | p65 |
T1221 | 147-162 | Transcription | denotes | transcriptional |
T1222 | 175-185 | Negative_regulation | denotes | inhibiting |
T1223 | 190-196 | Protein | denotes | SIRT-1 |
T1224 | 197-205 | Positive_regulation | denotes | mediated |
T1225 | 206-219 | Negative_regulation | denotes | deacetylation |
T1226 | 223-226 | Protein | denotes | p65 |
R1035 | T1215 | T1219 | causeOf | Tat,increased |
R1036 | T1215 | T1216 | causeOf | Tat,induced |
R1037 | T1215 | T1222 | causeOf | Tat,inhibiting |
R1038 | T1217 | T1216 | themeOf | degradation,induced |
R1039 | T1218 | T1217 | themeOf | IκB-α,degradation |
R1040 | T1220 | T1221 | themeOf | p65,transcriptional |
R1041 | T1221 | T1219 | themeOf | transcriptional,increased |
R1042 | T1222 | T1219 | causeOf | inhibiting,increased |
R1043 | T1223 | T1224 | causeOf | SIRT-1,mediated |
R1044 | T1224 | T1222 | themeOf | mediated,inhibiting |
R1045 | T1225 | T1224 | themeOf | deacetylation,mediated |
R1046 | T1226 | T1225 | themeOf | p65,deacetylation |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1407 | 53-56 | Protein | denotes | Tat |
T1408 | 57-64 | Positive_regulation | denotes | induced |
T1409 | 98-109 | Protein_catabolism | denotes | degradation |
T1410 | 113-118 | Protein | denotes | IκB-α |
T1411 | 143-146 | Protein | denotes | p65 |
T1412 | 175-185 | Negative_regulation | denotes | inhibiting |
T1413 | 190-196 | Protein | denotes | SIRT-1 |
T1414 | 197-205 | Positive_regulation | denotes | mediated |
T1415 | 206-219 | Deacetylation | denotes | deacetylation |
T1416 | 223-226 | Protein | denotes | p65 |
T1417 | 227-233 | Entity | denotes | Lys310 |
R1261 | T1407 | T1408 | causeOf | Tat,induced |
R1262 | T1407 | T1412 | causeOf | Tat,inhibiting |
R1263 | T1409 | T1408 | themeOf | degradation,induced |
R1264 | T1410 | T1409 | themeOf | IκB-α,degradation |
R1265 | T1413 | T1414 | causeOf | SIRT-1,mediated |
R1266 | T1414 | T1412 | themeOf | mediated,inhibiting |
R1267 | T1415 | T1414 | themeOf | deacetylation,mediated |
R1268 | T1417 | T1415 | themeOf | Lys310,deacetylation |
R1269 | T1417 | T1416 | partOf | Lys310,p65 |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2303 | 53-56 | P04605 | denotes | Tat |
T2304 | 53-56 | P04608 | denotes | Tat |
T2305 | 53-56 | P04610 | denotes | Tat |
T2306 | 53-56 | Q8UMQ1 | denotes | Tat |
T2307 | 143-146 | Q04206 | denotes | p65 |
T2308 | 143-146 | P21579 | denotes | p65 |
T2309 | 223-226 | Q04206 | denotes | p65 |
T2310 | 223-226 | P21579 | denotes | p65 |