PMC:3333881 / 1133-1579
Annnotations
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
22187158-18927578-77584393 | 380-381 | 18927578 | denotes | 1 |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T320 | 6-9 | CC | denotes | and |
T321 | 10-14 | NN | denotes | TLR2 |
T322 | 16-19 | PRP-DOLLAR- | denotes | Our |
T323 | 20-27 | NN | denotes | results |
T324 | 28-35 | VB | denotes | support |
T325 | 36-37 | DT | denotes | a |
T326 | 38-43 | JJ | denotes | novel |
T327 | 44-53 | NN | denotes | mechanism |
T328 | 54-56 | IN | denotes | of |
T329 | 57-62 | NN | denotes | NF-κB |
T330 | 63-73 | NN | denotes | activation |
T331 | 74-77 | IN | denotes | via |
T332 | 78-86 | JJ | denotes | physical |
T333 | 87-98 | NN | denotes | interaction |
T334 | 99-101 | IN | denotes | of |
T335 | 102-105 | NN | denotes | Tat |
T336 | 106-110 | IN | denotes | with |
T337 | 111-116 | NN | denotes | IκB-α |
T338 | 117-120 | CC | denotes | and |
T339 | 121-124 | NN | denotes | p65 |
T340 | 124-125 | -COMMA- | denotes | , |
T341 | 126-129 | CC | denotes | and |
T342 | 130-133 | MD | denotes | may |
T343 | 134-144 | VB | denotes | contribute |
T344 | 145-147 | TO | denotes | to |
T345 | 148-155 | JJ | denotes | further |
T346 | 156-164 | NN | denotes | insights |
T347 | 165-169 | IN | denotes | into |
T348 | 170-173 | DT | denotes | the |
T349 | 174-186 | NN | denotes | deregulation |
T350 | 187-189 | IN | denotes | of |
T351 | 190-193 | DT | denotes | the |
T352 | 194-206 | JJ | denotes | inflammatory |
T353 | 207-215 | NN | denotes | response |
T354 | 216-218 | IN | denotes | by |
T355 | 219-224 | NN | denotes | HIV-1 |
T1454 | 240-247 | JJ | denotes | Nuclear |
T1455 | 248-254 | NN | denotes | factor |
T1456 | 255-256 | -LRB- | denotes | ( |
T1457 | 256-258 | NN | denotes | NF |
T1458 | 258-259 | -RRB- | denotes | ) |
T1459 | 259-262 | NN | denotes | -κB |
T1460 | 263-276 | NN | denotes | transcription |
T1461 | 277-284 | NN | denotes | factors |
T1462 | 285-293 | VB | denotes | regulate |
T1463 | 294-297 | DT | denotes | the |
T1464 | 298-311 | NN | denotes | transcription |
T1465 | 312-314 | IN | denotes | of |
T1466 | 315-320 | NN | denotes | genes |
T1467 | 321-325 | WDT | denotes | that |
T1468 | 326-329 | VB | denotes | are |
T1469 | 330-338 | VB | denotes | involved |
T1470 | 339-341 | IN | denotes | in |
T1471 | 342-345 | DT | denotes | the |
T1472 | 346-352 | JJ | denotes | immune |
T1473 | 353-356 | CC | denotes | and |
T1474 | 357-369 | JJ | denotes | inflammatory |
T1475 | 370-378 | NN | denotes | response |
T1476 | 379-380 | -LRB- | denotes | ( |
T1477 | 380-381 | CD | denotes | 1 |
T1478 | 381-382 | -RRB- | denotes | ) |
T1479 | 384-387 | DT | denotes | The |
T1480 | 388-393 | NN | denotes | NF-κB |
T1481 | 394-400 | NN | denotes | family |
T1482 | 401-409 | VB | denotes | includes |
T1483 | 410-418 | NN | denotes | RelA/p65 |
T1484 | 418-419 | -COMMA- | denotes | , |
T1485 | 420-425 | NN | denotes | c-Rel |
T1486 | 425-426 | -COMMA- | denotes | , |
T1487 | 427-431 | NN | denotes | RelB |
T1488 | 431-432 | -COMMA- | denotes | , |
T1489 | 433-436 | NN | denotes | p50 |
T1490 | 437-440 | CC | denotes | and |
T1491 | 441-444 | NN | denotes | p52 |
R257 | T321 | T320 | arg2Of | TLR2,and |
R258 | T323 | T322 | arg1Of | results,Our |
R259 | T323 | T324 | arg1Of | results,support |
R260 | T323 | T342 | arg1Of | results,may |
R261 | T323 | T343 | arg1Of | results,contribute |
R262 | T324 | T341 | arg1Of | support,and |
R263 | T327 | T324 | arg2Of | mechanism,support |
R264 | T327 | T325 | arg1Of | mechanism,a |
R265 | T327 | T326 | arg1Of | mechanism,novel |
R266 | T327 | T328 | arg1Of | mechanism,of |
R267 | T327 | T331 | arg1Of | mechanism,via |
R268 | T330 | T328 | arg2Of | activation,of |
R269 | T330 | T329 | arg1Of | activation,NF-κB |
R270 | T333 | T331 | arg2Of | interaction,via |
R271 | T333 | T332 | arg1Of | interaction,physical |
R272 | T333 | T334 | arg1Of | interaction,of |
R273 | T333 | T336 | arg1Of | interaction,with |
R274 | T335 | T334 | arg2Of | Tat,of |
R275 | T337 | T338 | arg1Of | IκB-α,and |
R276 | T338 | T336 | arg2Of | and,with |
R277 | T339 | T338 | arg2Of | p65,and |
R278 | T341 | T340 | arg1Of | and,"," |
R279 | T343 | T341 | arg2Of | contribute,and |
R280 | T343 | T342 | arg2Of | contribute,may |
R281 | T343 | T344 | arg1Of | contribute,to |
R282 | T346 | T344 | arg2Of | insights,to |
R283 | T346 | T345 | arg1Of | insights,further |
R284 | T346 | T347 | arg1Of | insights,into |
R285 | T349 | T347 | arg2Of | deregulation,into |
R286 | T349 | T348 | arg1Of | deregulation,the |
R287 | T349 | T350 | arg1Of | deregulation,of |
R288 | T349 | T354 | arg1Of | deregulation,by |
R289 | T353 | T350 | arg2Of | response,of |
R290 | T353 | T351 | arg1Of | response,the |
R291 | T353 | T352 | arg1Of | response,inflammatory |
R292 | T355 | T354 | arg2Of | HIV-1,by |
R1275 | T1457 | T1456 | arg2Of | NF,( |
R1276 | T1458 | T1456 | arg3Of | ),( |
R1279 | T1461 | T1454 | arg1Of | factors,Nuclear |
R1280 | T1461 | T1455 | arg1Of | factors,factor |
R1281 | T1461 | T1456 | arg1Of | factors,( |
R1282 | T1461 | T1459 | arg1Of | factors,-κB |
R1285 | T1464 | T1465 | arg1Of | transcription,of |
R1286 | T1466 | T1465 | arg2Of | genes,of |
R1287 | T1466 | T1467 | arg1Of | genes,that |
R1288 | T1466 | T1468 | arg1Of | genes,are |
R1289 | T1466 | T1469 | arg2Of | genes,involved |
R1290 | T1469 | T1468 | arg2Of | involved,are |
R1291 | T1469 | T1470 | arg1Of | involved,in |
R1292 | T1472 | T1473 | arg1Of | immune,and |
R1293 | T1474 | T1473 | arg2Of | inflammatory,and |
R1294 | T1475 | T1470 | arg2Of | response,in |
R1295 | T1475 | T1471 | arg1Of | response,the |
R1296 | T1475 | T1472 | arg1Of | response,immune |
R1297 | T1475 | T1474 | arg1Of | response,inflammatory |
R1298 | T1475 | T1476 | arg1Of | response,( |
R1299 | T1477 | T1476 | arg2Of | 1,( |
R1300 | T1478 | T1476 | arg3Of | ),( |
R1301 | T1481 | T1479 | arg1Of | family,The |
R1302 | T1481 | T1480 | arg1Of | family,NF-κB |
R1303 | T1481 | T1482 | arg1Of | family,includes |
R1304 | T1483 | T1484 | arg1Of | RelA/p65,"," |
R1305 | T1484 | T1486 | arg1Of | ",","," |
R1306 | T1485 | T1484 | arg2Of | c-Rel,"," |
R1307 | T1486 | T1488 | arg1Of | ",","," |
R1308 | T1487 | T1486 | arg2Of | RelB,"," |
R1309 | T1488 | T1482 | arg2Of | ",",includes |
R1312 | T1489 | T1490 | arg1Of | p50,and |
R1313 | T1490 | T1488 | arg2Of | and,"," |
R1314 | T1491 | T1490 | arg2Of | p52,and |
R1277 | T1461 | T1460 | arg1Of | factors,transcription |
R1278 | T1461 | T1462 | arg1Of | factors,regulate |
R1283 | T1464 | T1462 | arg2Of | transcription,regulate |
R1284 | T1464 | T1463 | arg1Of | transcription,the |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T587 | 6-9 | CC | denotes | and |
T588 | 10-14 | NNP | denotes | TLR2 |
T589 | 14-15 | . | denotes | . |
T590 | 16-19 | PRP$ | denotes | Our |
T591 | 20-27 | NNS | denotes | results |
T592 | 28-35 | VBP | denotes | support |
T593 | 36-37 | DT | denotes | a |
T594 | 38-43 | NN | denotes | novel |
T595 | 44-53 | NN | denotes | mechanism |
T596 | 54-56 | IN | denotes | of |
T597 | 57-62 | JJ | denotes | NF-κB |
T598 | 63-73 | NN | denotes | activation |
T599 | 74-77 | IN | denotes | via |
T600 | 78-86 | JJ | denotes | physical |
T601 | 87-98 | NN | denotes | interaction |
T602 | 99-101 | IN | denotes | of |
T603 | 102-105 | NNP | denotes | Tat |
T604 | 106-110 | IN | denotes | with |
T605 | 111-116 | NNP | denotes | IκB-α |
T606 | 117-120 | CC | denotes | and |
T607 | 121-124 | CD | denotes | p65 |
T608 | 124-125 | , | denotes | , |
T609 | 126-129 | CC | denotes | and |
T610 | 130-133 | MD | denotes | may |
T611 | 134-144 | VB | denotes | contribute |
T612 | 145-147 | TO | denotes | to |
T613 | 148-155 | JJ | denotes | further |
T614 | 156-164 | NNS | denotes | insights |
T615 | 165-169 | IN | denotes | into |
T616 | 170-173 | DT | denotes | the |
T617 | 174-186 | NN | denotes | deregulation |
T618 | 187-189 | IN | denotes | of |
T619 | 190-193 | DT | denotes | the |
T620 | 194-206 | JJ | denotes | inflammatory |
T621 | 207-215 | NN | denotes | response |
T622 | 216-218 | IN | denotes | by |
T623 | 219-224 | NNP | denotes | HIV-1 |
T624 | 224-225 | . | denotes | . |
T2329 | 240-247 | NNP | denotes | Nuclear |
T2330 | 248-254 | NN | denotes | factor |
T2331 | 255-256 | -LRB- | denotes | ( |
T2332 | 256-258 | NNP | denotes | NF |
T2333 | 258-259 | -RRB- | denotes | ) |
T2334 | 259-260 | : | denotes | - |
T2335 | 260-262 | NN | denotes | κB |
T2336 | 263-276 | NN | denotes | transcription |
T2337 | 277-284 | NNS | denotes | factors |
T2338 | 285-293 | VB | denotes | regulate |
T2339 | 294-297 | DT | denotes | the |
T2340 | 298-311 | NN | denotes | transcription |
T2341 | 312-314 | IN | denotes | of |
T2342 | 315-320 | NNS | denotes | genes |
T2343 | 321-325 | WDT | denotes | that |
T2344 | 326-329 | VBP | denotes | are |
T2345 | 330-338 | VBN | denotes | involved |
T2346 | 339-341 | IN | denotes | in |
T2347 | 342-345 | DT | denotes | the |
T2348 | 346-352 | JJ | denotes | immune |
T2349 | 353-356 | CC | denotes | and |
T2350 | 357-369 | JJ | denotes | inflammatory |
T2351 | 370-378 | NN | denotes | response |
T2352 | 379-380 | -LRB- | denotes | ( |
T2353 | 380-381 | CD | denotes | 1 |
T2354 | 381-382 | -RRB- | denotes | ) |
T2355 | 382-383 | . | denotes | . |
T2356 | 384-387 | DT | denotes | The |
T2357 | 388-393 | NNP | denotes | NF-κB |
T2358 | 394-400 | NN | denotes | family |
T2359 | 401-409 | VBZ | denotes | includes |
T2360 | 410-418 | NNS | denotes | RelA/p65 |
T2361 | 418-419 | , | denotes | , |
T2362 | 420-425 | NNP | denotes | c-Rel |
T2363 | 425-426 | , | denotes | , |
T2364 | 427-431 | NNP | denotes | RelB |
T2365 | 431-432 | , | denotes | , |
T2366 | 433-436 | CD | denotes | p50 |
T2367 | 437-440 | CC | denotes | and |
T2368 | 441-444 | CD | denotes | p52 |
R481 | T590 | T591 | poss | Our,results |
R482 | T591 | T592 | nsubj | results,support |
R483 | T592 | T592 | ROOT | support,support |
R484 | T593 | T595 | det | a,mechanism |
R485 | T594 | T595 | amod | novel,mechanism |
R486 | T595 | T592 | dobj | mechanism,support |
R487 | T596 | T595 | prep | of,mechanism |
R488 | T597 | T598 | amod | NF-κB,activation |
R489 | T598 | T596 | pobj | activation,of |
R490 | T599 | T592 | prep | via,support |
R491 | T600 | T601 | amod | physical,interaction |
R492 | T601 | T599 | pobj | interaction,via |
R493 | T602 | T601 | prep | of,interaction |
R494 | T603 | T602 | pobj | Tat,of |
R495 | T604 | T601 | prep | with,interaction |
R496 | T605 | T604 | pobj | IκB-α,with |
R497 | T606 | T605 | cc | and,IκB-α |
R498 | T607 | T605 | conj | p65,IκB-α |
R499 | T608 | T592 | punct | ",",support |
R500 | T609 | T592 | cc | and,support |
R501 | T610 | T611 | aux | may,contribute |
R502 | T611 | T592 | conj | contribute,support |
R503 | T612 | T611 | prep | to,contribute |
R504 | T613 | T614 | amod | further,insights |
R505 | T614 | T612 | pobj | insights,to |
R506 | T615 | T614 | prep | into,insights |
R507 | T616 | T617 | det | the,deregulation |
R508 | T617 | T615 | pobj | deregulation,into |
R509 | T618 | T617 | prep | of,deregulation |
R510 | T619 | T621 | det | the,response |
R511 | T620 | T621 | amod | inflammatory,response |
R512 | T621 | T618 | pobj | response,of |
R513 | T622 | T621 | prep | by,response |
R514 | T623 | T622 | pobj | HIV-1,by |
R515 | T624 | T592 | punct | .,support |
R2065 | T2329 | T2330 | compound | Nuclear,factor |
R2066 | T2330 | T2337 | nmod | factor,factors |
R2067 | T2331 | T2332 | punct | (,NF |
R2068 | T2332 | T2330 | appos | NF,factor |
R2069 | T2333 | T2332 | punct | ),NF |
R2070 | T2334 | T2335 | punct | -,κB |
R2071 | T2335 | T2337 | amod | κB,factors |
R2072 | T2336 | T2337 | compound | transcription,factors |
R2073 | T2337 | T2338 | nsubj | factors,regulate |
R2074 | T2338 | T2338 | ROOT | regulate,regulate |
R2075 | T2339 | T2340 | det | the,transcription |
R2076 | T2340 | T2338 | dobj | transcription,regulate |
R2077 | T2341 | T2340 | prep | of,transcription |
R2078 | T2342 | T2341 | pobj | genes,of |
R2079 | T2343 | T2345 | nsubjpass | that,involved |
R2080 | T2344 | T2345 | auxpass | are,involved |
R2082 | T2345 | T2342 | relcl | involved,genes |
R2083 | T2346 | T2345 | prep | in,involved |
R2085 | T2347 | T2351 | det | the,response |
R2086 | T2348 | T2351 | amod | immune,response |
R2089 | T2349 | T2348 | cc | and,immune |
R2091 | T2350 | T2348 | conj | inflammatory,immune |
R2092 | T2351 | T2346 | pobj | response,in |
R2093 | T2352 | T2353 | punct | (,1 |
R2094 | T2353 | T2342 | appos | 1,genes |
R2096 | T2354 | T2353 | punct | ),1 |
R2097 | T2355 | T2338 | punct | .,regulate |
R2098 | T2356 | T2358 | det | The,family |
R2099 | T2357 | T2358 | compound | NF-κB,family |
R2100 | T2358 | T2359 | nsubj | family,includes |
R2101 | T2359 | T2359 | ROOT | includes,includes |
R2103 | T2360 | T2359 | dobj | RelA/p65,includes |
R2104 | T2361 | T2360 | punct | ",",RelA/p65 |
R2105 | T2362 | T2360 | conj | c-Rel,RelA/p65 |
R2106 | T2363 | T2362 | punct | ",",c-Rel |
R2108 | T2364 | T2362 | conj | RelB,c-Rel |
R2109 | T2365 | T2364 | punct | ",",RelB |
R2110 | T2366 | T2364 | conj | p50,RelB |
R2112 | T2367 | T2366 | cc | and,p50 |
R2113 | T2368 | T2366 | conj | p52,p50 |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T635 | 57-73 | http://purl.obolibrary.org/obo/GO_0051092 | denotes | NF-κB activation |
T637 | 194-215 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
T3164 | 263-276 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T3165 | 298-311 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T3170 | 357-378 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T96 | 16-225 | Sentence | denotes | Our results support a novel mechanism of NF-κB activation via physical interaction of Tat with IκB-α and p65, and may contribute to further insights into the deregulation of the inflammatory response by HIV-1. |
T1429 | 240-383 | Sentence | denotes | Nuclear factor (NF)-κB transcription factors regulate the transcription of genes that are involved in the immune and inflammatory response (1). |
T9 | 16-225 | Sentence | denotes | Our results support a novel mechanism of NF-κB activation via physical interaction of Tat with IκB-α and p65, and may contribute to further insights into the deregulation of the inflammatory response by HIV-1. |
T10 | 227-239 | Sentence | denotes | INTRODUCTION |
T11 | 240-383 | Sentence | denotes | Nuclear factor (NF)-κB transcription factors regulate the transcription of genes that are involved in the immune and inflammatory response (1). |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T898 | 10-14 | Protein | denotes | TLR2 |
T899 | 87-98 | Binding | denotes | interaction |
T900 | 102-105 | Protein | denotes | Tat |
T901 | 111-116 | Protein | denotes | IκB-α |
T902 | 121-124 | Protein | denotes | p65 |
T3998 | 410-414 | Protein | denotes | RelA |
T3999 | 415-418 | Protein | denotes | p65 |
T4000 | 420-425 | Protein | denotes | c-Rel |
T4001 | 427-431 | Protein | denotes | RelB |
T4002 | 433-436 | Protein | denotes | p50 |
T4003 | 441-444 | Protein | denotes | p52 |
R629 | T900 | T899 | themeOf | Tat,interaction |
R630 | T901 | T899 | themeOf | IκB-α,interaction |
R3639 | T3999 | T3998 | equivalentTo | p65,RelA |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T941 | 10-14 | Protein | denotes | TLR2 |
T946 | 57-62 | Protein | denotes | NF-κB |
T947 | 102-105 | Protein | denotes | Tat |
T948 | 111-116 | Protein | denotes | IκB-α |
T949 | 121-124 | Protein | denotes | p65 |
T950 | 63-73 | Positive_regulation | denotes | activation |
T951 | 87-98 | Binding | denotes | interaction |
T4184 | 260-262 | Protein | denotes | κB |
T4185 | 285-293 | Regulation | denotes | regulate |
T4186 | 388-400 | Protein | denotes | NF-κB family |
T4187 | 410-414 | Protein | denotes | RelA |
T4188 | 415-418 | Protein | denotes | p65 |
T4189 | 420-425 | Protein | denotes | c-Rel |
T4190 | 427-431 | Protein | denotes | RelB |
T4191 | 433-436 | Protein | denotes | p50 |
T4192 | 441-444 | Protein | denotes | p52 |
R651 | T946 | T950 | themeOf | NF-κB,activation |
R652 | T947 | T951 | themeOf | Tat,interaction |
R653 | T948 | T951 | themeOf | IκB-α,interaction |
R3776 | T4184 | T4185 | themeOf | κB,regulate |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T84 | 10-14 | Protein | denotes | TLR2 |
T85 | 87-98 | Binding | denotes | interaction |
T86 | 102-105 | Protein | denotes | Tat |
T87 | 111-116 | Protein | denotes | IκB-α |
T88 | 121-124 | Protein | denotes | p65 |
T1138 | 410-414 | Protein | denotes | RelA |
T1139 | 415-418 | Protein | denotes | p65 |
T1140 | 420-425 | Protein | denotes | c-Rel |
T1141 | 427-431 | Protein | denotes | RelB |
T1142 | 433-436 | Protein | denotes | p50 |
T1143 | 441-444 | Protein | denotes | p52 |
R40 | T86 | T85 | themeOf | Tat,interaction |
R41 | T87 | T85 | themeOf | IκB-α,interaction |
R42 | T88 | T85 | themeOf | p65,interaction |
R976 | T1139 | T1138 | equivalentTo | p65,RelA |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T109 | 87-98 | Binding | denotes | interaction |
T1243 | 410-414 | Protein | denotes | RelA |
T1244 | 415-418 | Protein | denotes | p65 |
T1245 | 420-425 | Protein | denotes | c-Rel |
T1246 | 427-431 | Protein | denotes | RelB |
T1247 | 433-436 | Protein | denotes | p50 |
T1248 | 441-444 | Protein | denotes | p52 |
T129 | 10-14 | Protein | denotes | TLR2 |
T130 | 102-105 | Protein | denotes | Tat |
T131 | 111-116 | Protein | denotes | IκB-α |
T132 | 121-124 | Protein | denotes | p65 |
R681 | T130 | T109 | themeOf | Tat,interaction |
R682 | T131 | T109 | themeOf | IκB-α,interaction |
R1064 | T1244 | T1243 | equivalentTo | p65,RelA |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T395 | 10-14 | O60603 | denotes | TLR2 |
T396 | 102-105 | Q8UMQ1 | denotes | Tat |
T397 | 102-105 | P04608 | denotes | Tat |
T398 | 102-105 | P04610 | denotes | Tat |
T399 | 102-105 | P04605 | denotes | Tat |
T400 | 121-124 | Q04206 | denotes | p65 |
T401 | 121-124 | P21579 | denotes | p65 |
T2244 | 410-414 | Q04206-3 | denotes | RelA |
T2245 | 410-414 | Q04206 | denotes | RelA |
T2246 | 415-418 | Q04206 | denotes | p65 |
T2247 | 415-418 | P21579 | denotes | p65 |
T2248 | 420-425 | Q04864 | denotes | c-Rel |
T2249 | 422-425 | Q04864 | denotes | Rel |
T2250 | 427-431 | Q01201 | denotes | RelB |
T2251 | 433-436 | P19838 | denotes | p50 |
T2252 | 441-444 | Q00653 | denotes | p52 |