
PMC:3333881 / 10-422
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T144 | 13-20 | NN | denotes | virus-1 |
T145 | 21-24 | NN | denotes | Tat |
T146 | 25-34 | VB | denotes | activates |
T147 | 35-40 | NN | denotes | NF-κB |
T148 | 41-44 | IN | denotes | via |
T149 | 45-53 | JJ | denotes | physical |
T150 | 54-65 | NN | denotes | interaction |
T151 | 66-70 | IN | denotes | with |
T152 | 71-76 | NN | denotes | IκB-α |
T153 | 77-80 | CC | denotes | and |
T154 | 81-84 | NN | denotes | p65 |
T155 | 96-103 | JJ | denotes | Nuclear |
T156 | 104-110 | NN | denotes | factor |
T157 | 111-112 | -LRB- | denotes | ( |
T158 | 112-114 | NN | denotes | NF |
T159 | 114-115 | -RRB- | denotes | ) |
T160 | 115-118 | NN | denotes | -κB |
T161 | 119-121 | VB | denotes | is |
T162 | 122-123 | DT | denotes | a |
T163 | 124-130 | NN | denotes | master |
T164 | 131-140 | NN | denotes | regulator |
T165 | 141-143 | IN | denotes | of |
T166 | 144-160 | JJ | denotes | pro-inflammatory |
T167 | 161-166 | NN | denotes | genes |
T168 | 167-170 | CC | denotes | and |
T169 | 171-173 | VB | denotes | is |
T170 | 174-185 | VB | denotes | upregulated |
T171 | 186-188 | IN | denotes | in |
T172 | 189-194 | JJ | denotes | human |
T173 | 195-211 | NN | denotes | immunodeficiency |
T174 | 212-217 | NN | denotes | virus |
T175 | 218-219 | CD | denotes | 1 |
T176 | 220-221 | -LRB- | denotes | ( |
T177 | 221-226 | NN | denotes | HIV-1 |
T178 | 226-227 | -RRB- | denotes | ) |
T179 | 228-237 | NN | denotes | infection |
T180 | 239-249 | NN | denotes | Mechanisms |
T181 | 250-260 | VB | denotes | underlying |
T182 | 261-264 | DT | denotes | the |
T183 | 265-270 | NN | denotes | NF-κB |
T184 | 271-283 | NN | denotes | deregulation |
T185 | 284-286 | IN | denotes | by |
T186 | 287-292 | NN | denotes | HIV-1 |
T187 | 293-296 | VB | denotes | are |
T188 | 297-305 | JJ | denotes | relevant |
T189 | 306-309 | IN | denotes | for |
T190 | 310-316 | JJ | denotes | immune |
T191 | 317-328 | NN | denotes | dysfunction |
T192 | 329-331 | IN | denotes | in |
T193 | 332-336 | NN | denotes | AIDS |
T194 | 338-340 | PRP | denotes | We |
T195 | 341-347 | VB | denotes | report |
T196 | 348-352 | IN | denotes | that |
T197 | 353-355 | IN | denotes | in |
T198 | 356-362 | JJ | denotes | single |
T199 | 363-368 | JJ | denotes | round |
T200 | 369-374 | NN | denotes | HIV-1 |
T201 | 375-384 | NN | denotes | infection |
T202 | 384-385 | -COMMA- | denotes | , |
T203 | 386-388 | CC | denotes | or |
T204 | 389-401 | JJ | denotes | single-pulse |
T205 | 402-405 | NN | denotes | PMA |
R76 | T145 | T144 | arg1Of | Tat,virus-1 |
R77 | T145 | T146 | arg1Of | Tat,activates |
R78 | T146 | T148 | arg1Of | activates,via |
R79 | T147 | T146 | arg2Of | NF-κB,activates |
R80 | T150 | T148 | arg2Of | interaction,via |
R81 | T150 | T149 | arg1Of | interaction,physical |
R82 | T150 | T151 | arg1Of | interaction,with |
R83 | T152 | T153 | arg1Of | IκB-α,and |
R84 | T153 | T151 | arg2Of | and,with |
R85 | T154 | T153 | arg2Of | p65,and |
R86 | T156 | T155 | arg1Of | factor,Nuclear |
R87 | T156 | T157 | arg1Of | factor,( |
R88 | T158 | T157 | arg2Of | NF,( |
R89 | T159 | T157 | arg3Of | ),( |
R90 | T160 | T156 | arg1Of | -κB,factor |
R91 | T160 | T161 | arg1Of | -κB,is |
R92 | T160 | T169 | arg1Of | -κB,is |
R93 | T160 | T170 | arg2Of | -κB,upregulated |
R94 | T161 | T168 | arg1Of | is,and |
R95 | T164 | T161 | arg2Of | regulator,is |
R96 | T164 | T162 | arg1Of | regulator,a |
R97 | T164 | T163 | arg1Of | regulator,master |
R98 | T164 | T165 | arg1Of | regulator,of |
R99 | T167 | T165 | arg2Of | genes,of |
R100 | T167 | T166 | arg1Of | genes,pro-inflammatory |
R101 | T170 | T168 | arg2Of | upregulated,and |
R102 | T170 | T169 | arg2Of | upregulated,is |
R103 | T170 | T171 | arg1Of | upregulated,in |
R104 | T174 | T172 | arg1Of | virus,human |
R105 | T174 | T173 | arg1Of | virus,immunodeficiency |
R106 | T174 | T175 | arg1Of | virus,1 |
R107 | T174 | T176 | arg1Of | virus,( |
R108 | T177 | T176 | arg2Of | HIV-1,( |
R109 | T178 | T176 | arg3Of | ),( |
R110 | T179 | T171 | arg2Of | infection,in |
R111 | T179 | T174 | arg1Of | infection,virus |
R112 | T180 | T181 | arg1Of | Mechanisms,underlying |
R113 | T180 | T187 | arg1Of | Mechanisms,are |
R114 | T180 | T188 | arg1Of | Mechanisms,relevant |
R115 | T184 | T181 | arg2Of | deregulation,underlying |
R116 | T184 | T182 | arg1Of | deregulation,the |
R117 | T184 | T183 | arg1Of | deregulation,NF-κB |
R118 | T184 | T185 | arg1Of | deregulation,by |
R119 | T186 | T185 | arg2Of | HIV-1,by |
R120 | T188 | T187 | arg2Of | relevant,are |
R121 | T188 | T189 | arg1Of | relevant,for |
R122 | T191 | T189 | arg2Of | dysfunction,for |
R123 | T191 | T190 | arg1Of | dysfunction,immune |
R124 | T191 | T192 | arg1Of | dysfunction,in |
R125 | T193 | T192 | arg2Of | AIDS,in |
R126 | T194 | T195 | arg1Of | We,report |
R127 | T201 | T198 | arg1Of | infection,single |
R128 | T201 | T199 | arg1Of | infection,round |
R129 | T201 | T200 | arg1Of | infection,HIV-1 |
R130 | T201 | T203 | arg1Of | infection,or |
R131 | T203 | T197 | arg2Of | or,in |
R132 | T203 | T202 | arg1Of | or,"," |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T404 | 13-20 | JJ | denotes | virus-1 |
T405 | 21-24 | NNP | denotes | Tat |
T406 | 25-34 | VBZ | denotes | activates |
T407 | 35-40 | NNP | denotes | NF-κB |
T408 | 41-44 | IN | denotes | via |
T409 | 45-53 | JJ | denotes | physical |
T410 | 54-65 | NN | denotes | interaction |
T411 | 66-70 | IN | denotes | with |
T412 | 71-76 | NNP | denotes | IκB-α |
T413 | 77-80 | CC | denotes | and |
T414 | 81-84 | CD | denotes | p65 |
T415 | 96-103 | JJ | denotes | Nuclear |
T416 | 104-110 | NN | denotes | factor |
T417 | 111-112 | -LRB- | denotes | ( |
T418 | 112-114 | NNP | denotes | NF |
T419 | 114-115 | -RRB- | denotes | ) |
T420 | 115-116 | : | denotes | - |
T421 | 116-118 | NN | denotes | κB |
T422 | 119-121 | VBZ | denotes | is |
T423 | 122-123 | DT | denotes | a |
T424 | 124-130 | NN | denotes | master |
T425 | 131-140 | NN | denotes | regulator |
T426 | 141-143 | IN | denotes | of |
T427 | 144-160 | JJ | denotes | pro-inflammatory |
T428 | 161-166 | NNS | denotes | genes |
T429 | 167-170 | CC | denotes | and |
T430 | 171-173 | VBZ | denotes | is |
T431 | 174-185 | VBN | denotes | upregulated |
T432 | 186-188 | IN | denotes | in |
T433 | 189-194 | JJ | denotes | human |
T434 | 195-211 | NN | denotes | immunodeficiency |
T435 | 212-217 | NN | denotes | virus |
T436 | 218-219 | CD | denotes | 1 |
T437 | 220-221 | -LRB- | denotes | ( |
T438 | 221-226 | NN | denotes | HIV-1 |
T439 | 226-227 | -RRB- | denotes | ) |
T440 | 228-237 | NN | denotes | infection |
T441 | 237-238 | . | denotes | . |
T442 | 239-249 | NNPS | denotes | Mechanisms |
T443 | 250-260 | VBG | denotes | underlying |
T444 | 261-264 | DT | denotes | the |
T445 | 265-270 | JJ | denotes | NF-κB |
T446 | 271-283 | NN | denotes | deregulation |
T447 | 284-286 | IN | denotes | by |
T448 | 287-292 | NNP | denotes | HIV-1 |
T449 | 293-296 | VBP | denotes | are |
T450 | 297-305 | JJ | denotes | relevant |
T451 | 306-309 | IN | denotes | for |
T452 | 310-316 | JJ | denotes | immune |
T453 | 317-328 | NN | denotes | dysfunction |
T454 | 329-331 | IN | denotes | in |
T455 | 332-336 | NNP | denotes | AIDS |
T456 | 336-337 | . | denotes | . |
T457 | 338-340 | PRP | denotes | We |
T458 | 341-347 | VBP | denotes | report |
T459 | 348-352 | IN | denotes | that |
T460 | 353-355 | IN | denotes | in |
T461 | 356-362 | JJ | denotes | single |
T462 | 363-368 | NN | denotes | round |
T463 | 369-374 | NN | denotes | HIV-1 |
T464 | 375-384 | NN | denotes | infection |
T465 | 384-385 | , | denotes | , |
T466 | 386-388 | CC | denotes | or |
T467 | 389-401 | JJ | denotes | single-pulse |
T468 | 402-405 | NNP | denotes | PMA |
R295 | T404 | T405 | compound | virus-1,Tat |
R296 | T405 | T406 | nsubj | Tat,activates |
R297 | T406 | T422 | ccomp | activates,is |
R298 | T407 | T406 | dobj | NF-κB,activates |
R299 | T408 | T406 | prep | via,activates |
R300 | T409 | T410 | amod | physical,interaction |
R301 | T410 | T408 | pobj | interaction,via |
R302 | T411 | T410 | prep | with,interaction |
R303 | T412 | T411 | pobj | IκB-α,with |
R304 | T413 | T412 | cc | and,IκB-α |
R305 | T414 | T416 | nummod | p65,factor |
R306 | T415 | T416 | amod | Nuclear,factor |
R307 | T416 | T410 | conj | factor,interaction |
R308 | T417 | T410 | punct | (,interaction |
R309 | T418 | T406 | npadvmod | NF,activates |
R310 | T419 | T418 | punct | ),NF |
R311 | T420 | T422 | punct | -,is |
R312 | T421 | T422 | nsubj | κB,is |
R313 | T422 | T422 | ROOT | is,is |
R314 | T423 | T425 | det | a,regulator |
R315 | T424 | T425 | compound | master,regulator |
R316 | T425 | T422 | attr | regulator,is |
R317 | T426 | T425 | prep | of,regulator |
R318 | T427 | T428 | amod | pro-inflammatory,genes |
R319 | T428 | T426 | pobj | genes,of |
R320 | T429 | T422 | cc | and,is |
R321 | T430 | T431 | auxpass | is,upregulated |
R322 | T431 | T422 | conj | upregulated,is |
R323 | T432 | T431 | prep | in,upregulated |
R324 | T433 | T434 | amod | human,immunodeficiency |
R325 | T434 | T435 | compound | immunodeficiency,virus |
R326 | T435 | T432 | pobj | virus,in |
R327 | T436 | T435 | nummod | 1,virus |
R328 | T437 | T440 | punct | (,infection |
R329 | T438 | T440 | nmod | HIV-1,infection |
R330 | T439 | T440 | punct | ),infection |
R331 | T440 | T435 | appos | infection,virus |
R332 | T441 | T422 | punct | .,is |
R333 | T442 | T449 | nsubj | Mechanisms,are |
R334 | T443 | T442 | acl | underlying,Mechanisms |
R335 | T444 | T446 | det | the,deregulation |
R336 | T445 | T446 | amod | NF-κB,deregulation |
R337 | T446 | T443 | dobj | deregulation,underlying |
R338 | T447 | T446 | prep | by,deregulation |
R339 | T448 | T447 | pobj | HIV-1,by |
R340 | T449 | T449 | ROOT | are,are |
R341 | T450 | T449 | acomp | relevant,are |
R342 | T451 | T450 | prep | for,relevant |
R343 | T452 | T453 | amod | immune,dysfunction |
R344 | T453 | T451 | pobj | dysfunction,for |
R345 | T454 | T453 | prep | in,dysfunction |
R346 | T455 | T454 | pobj | AIDS,in |
R347 | T456 | T449 | punct | .,are |
R348 | T457 | T458 | nsubj | We,report |
R349 | T458 | T458 | ROOT | report,report |
R352 | T461 | T464 | amod | single,infection |
R353 | T462 | T464 | compound | round,infection |
R354 | T463 | T464 | compound | HIV-1,infection |
R355 | T464 | T460 | pobj | infection,in |
R356 | T465 | T460 | punct | ",",in |
R357 | T466 | T460 | cc | or,in |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T633 | 25-40 | http://purl.obolibrary.org/obo/GO_0051092 | denotes | activates NF-κB |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T90 | 96-238 | Sentence | denotes | Nuclear factor (NF)-κB is a master regulator of pro-inflammatory genes and is upregulated in human immunodeficiency virus 1 (HIV-1) infection. |
T91 | 239-337 | Sentence | denotes | Mechanisms underlying the NF-κB deregulation by HIV-1 are relevant for immune dysfunction in AIDS. |
T2 | 87-95 | Sentence | denotes | Abstract |
T3 | 96-238 | Sentence | denotes | Nuclear factor (NF)-κB is a master regulator of pro-inflammatory genes and is upregulated in human immunodeficiency virus 1 (HIV-1) infection. |
T4 | 239-337 | Sentence | denotes | Mechanisms underlying the NF-κB deregulation by HIV-1 are relevant for immune dysfunction in AIDS. |
ICD10
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T639 | 195-211 | http://purl.bioontology.org/ontology/ICD10/D84.9 | denotes | immunodeficiency |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T858 | 21-24 | Protein | denotes | Tat |
T859 | 54-65 | Binding | denotes | interaction |
T860 | 71-76 | Protein | denotes | IκB-α |
T861 | 81-84 | Protein | denotes | p65 |
R741 | T858 | T859 | themeOf | Tat,interaction |
R742 | T860 | T859 | themeOf | IκB-α,interaction |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T903 | 21-24 | Protein | denotes | Tat |
T904 | 35-40 | Protein | denotes | NF-κB |
T905 | 71-76 | Protein | denotes | IκB-α |
T906 | 25-34 | Positive_regulation | denotes | activates |
T907 | 54-65 | Binding | denotes | interaction |
T908 | 25-34 | Positive_regulation | denotes | activates |
T909 | 116-118 | Protein | denotes | κB |
T910 | 174-185 | Positive_regulation | denotes | upregulated |
T911 | 265-270 | Protein | denotes | NF-κB |
T912 | 271-283 | Regulation | denotes | deregulation |
R631 | T903 | T906 | causeOf | Tat,activates |
R632 | T903 | T908 | causeOf | Tat,activates |
R633 | T904 | T906 | themeOf | NF-κB,activates |
R634 | T905 | T907 | themeOf | IκB-α,interaction |
R635 | T907 | T908 | themeOf | interaction,activates |
R636 | T909 | T910 | themeOf | κB,upregulated |
R637 | T911 | T912 | themeOf | NF-κB,deregulation |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T46 | 21-24 | Protein | denotes | Tat |
T47 | 54-65 | Binding | denotes | interaction |
T48 | 71-76 | Protein | denotes | IκB-α |
T49 | 81-84 | Protein | denotes | p65 |
R654 | T46 | T47 | themeOf | Tat,interaction |
R655 | T48 | T47 | themeOf | IκB-α,interaction |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T97 | 54-65 | Binding | denotes | interaction |
T117 | 21-24 | Protein | denotes | Tat |
T127 | 71-76 | Protein | denotes | IκB-α |
T133 | 81-84 | Protein | denotes | p65 |
R51 | T117 | T97 | themeOf | Tat,interaction |
R61 | T127 | T97 | themeOf | IκB-α,interaction |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T358 | 21-24 | P04608 | denotes | Tat |
T359 | 21-24 | P04605 | denotes | Tat |
T360 | 21-24 | P04610 | denotes | Tat |
T361 | 21-24 | Q8UMQ1 | denotes | Tat |
T362 | 81-84 | P21579 | denotes | p65 |
T363 | 81-84 | Q04206 | denotes | p65 |